1XSZA

The structure of ralf
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
356
structure length
356
Chain Sequence
GASHPEIEKAQREIIEAFNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQVLKAFTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAAYLLAFQTIMLNTDLHNPSIPEKNKMTVDGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPFELNFVKTSPGYELTSTTLNKDSTFKKLDSFLHSTDVNINTVFPGIGDNVKTTVDQPKSWLSFFTGYKGTITLTDNKTSAQATIQVYTPNIFSKWLFGEQPRVIIQPGQTKESIDLAAKAAADFSSPVKNFKATYDYEVGDLIKAYDNQKKLITIERNLALKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site
pubmed doi rcsb
molecule tags Signaling protein
source organism Legionella pneumophila
molecule keywords guanine nucleotide exchange protein
total genus 129
structure length 356
sequence length 356
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-10-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01369 Sec7 Sec7 domain
A PF18248 RalF_SCD RalF C-terminal Sec-7 capping domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 1xszA01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 1xszA02
3.30.310.140 Alpha Beta 2-Layer Sandwich TATA-Binding Protein sec7 domains 1xszA03
3SWVA 1R8ME 1R8QE 1XSZA 4JMIA 4C0AA 1BC9A 4D7QA 1KU1A 1S9DE 4A4PA 1XT0B 3L8NA 4OIYA 1R8SE 2R09A 4L5MA 4C7PA 4JWLA 3LTLA 4D7RA 2R0DA 1RE0B 4JXHA 4Z21A 1PBVA 4JMOA
chains in the Genus database with same CATH superfamily
2VXGA 1A8BA 1PCMX 5BMPA 1UT4A 3OSTA 2QRCA 1LWVA 2NVMA 1QTSA 2IE7A 1C1KA 1R8SE 4WXAA 1BCWA 1N41A 4Q11A 1BCZA 2JHJA 4Q2SA 3PMGA 1LKVX 2EHBD 1AVHA 5IYCP 2HL8A 2HYWA 2YH5A 2II2A 5EPCA 1EUVA 1ANWA 2HKPA 2Y8QA 1R4AE 4EAKA 3I0XA 1PVSA 1AIIA 3OH6A 1M3HA 4OIYA 1QNCA 4FHRB 3ENCA 3CWUA 3RPJA 1N00A 1BC3A 1YQMA 1HU0A 1K35A 3ENOC 4C0AA 4EJZA 2V8QA 3CWSA 1G5NA 2V9JA 1B9KA 1M5Q1 2H5AX 4MRQA 2YA3A 3OC3C 2HL9A 1KO9A 1YTBA 1PBVA 1M3QA 2NOLA 2NLVA 2MZ8A 1QTPA 1NGMA 2ZHIA 2Z8UA 1QNEA 2OY9A 2D0BA 3F10A 1TBPA 1A8AA 1BC1A 3ABQA 1K2YX 2ZOCA 3HS9A 2FKFA 1DK5A 1P5GX 2Z0FA 5JMVD 1AISA 1LXTA 1BC0A 1WJWA 3SOHB 1QN4A 2FGTA 1KY7A 3OGDA 1R4XA 1R8QE 1EBMA 1YQRA 1QN6A 3SNSA 2OOXA 3H1ZA 1QN5A 2JHNA 1HVEA 3AO0A 2JOIA 4C7PA 4EAJA 2NOHA 4D7RA 3CWTA 1AVCA 1V5SA 3BKQX 1AOWA 1W7BA 2DKCA 2O3OA 3EIKA 2VJ0A 2HZSA 1VOLB 3ULXA 3RSMA 3TE5A 2H0KA 4EALA 3AJCA 1ANNA 4I8OA 2NOBA 3UW2A 2IV9A 1AXNA 1J3MA 2QEZA 3I0WA 1C9BB 1KFQA 2XO2A 1R8ME 2NOFA 1BO9A 4X9PA 4PY5A 1KY6A 1QN3A 4HJHA 3TDHA 3OLPA 4L5MA 5IYBP 1QNAA 1DIZA 2Q4CA 3OSMA 5KL0A 2R0DA 1XSZA 2IV8A 4HREA 2D0AA 3CW7A 2D0CA 1XJLA 2QRDA 1VTLE 1JFIC 2V92A 3L8NA 2MJ7A 4EAIA 3N89A 1YTFA 3USYA 3ABRA 5IYDP 3LTLA 1N3CA 1HVGA 1M9IA 1PCJX 2HYVA 1QN7A 5JN5A 3ABSA 1HM6A 3BRXA 1UT7A 4ROCB 3HJLA 1Q8DA 3OH9A 2DKDA 3USWA 2IICA 3KRMA 2NOZA 1PCZA 1N44A 3IH7A 1QN8A 1QN9A 5HSHA 1VTOA 3CVSA 2QLVA 4KN7X 1TGHA 4JMIA 3OCIA 1TUOA 1CDWA 3CWAA 1I4AA 2I5WA 4B0AA 4WX8A 1ANXA 3T4NA 1KFIA 1DM5A 2ZHJA 4JXHA 4RODB 2HSNA 3I3WA 3OSEA 2NOIA 2R5XA 2H4LX 2HZMA 2XHIA 1BCYA 2OOYA 4EAGA 3ANYA 1FN7A 1MCXA 1RE0B 1AVRA 2DKAA 2QR1A 3F0ZA 1YQLA 3DPUA 2IE6A 2JPIA 2HYUA 5F9CA 1T6AA 3D4VA 4EJYA 4TPSA 1N3AA 1NVPA 2RANA 4QG5A 1HAKA 2LAEA 1N42A 4EVFA 3KTUA 1C47A 2NWVA 1C4GA 1QNBA 4BJUA 4KMUX 4IL8A 4JK1X 2F7LA 1SAVA 3DPTA 1BC9A 1YJ0A 4ROEB 1S9DE 4A4PA 1LWWA 4MDUA 1N39A 3NA5A 4MDVA 3D7QA 4JWLA 1W3WA 4Z21A 2H0LA 3ASMA 1TBAB 1HVDA 1LWYA 1XT0B 2PWWA 1Q9UA 1P5DX 1MPGA 1KYUA 1YIIA 1JDYA 4D7QA 4JMOA 2H0MA 1E42A 1PZDA 4KN4X 4DULA 1YGMA 1KU1A 1VOKA 1WQAA 1W80A 1ALAA 2FUVA 3VN5A 5BMNA 2Y8LA 3C04A 2QREA 1YCNA 1UL7A 2K6XA 3ABOA 2NOEA 1QC7A 1VKLA 1KYDA 4WZSD 1YQKA 3SWVA 4EVHA 2ZFDB 1NH2A 5AN4A 3PDKA 4CFFA 2XO3A 3CVTA 1HVFA 3TW5A 1MP9A 4FQ0C 1W45A 2FKMX 2G30A 1UPTB 1RM1A 1D3UA 2R09A 3EAYA 3HS8A 1KYFA 1AEIA
chains in the Genus database with same CATH topology
2HSNA 4KMUX 3SWVA 1R8ME 4JK1X 1R8QE 4KN7X 3HJLA 1Q8DA 4JMIA 4KN4X 4C0AA 3TW5A 1BC9A 3USWA 4D7QA 1KU1A 4FQ0C 4JMOA 1S9DE 4A4PA 1XT0B 3L8NA 3AJCA 4OIYA 1R8SE 2R09A 4FHRB 4L5MA 4C7PA 3USYA 1LKVX 4JWLA 3LTLA 4D7RA 2K6XA 2R0DA 3SOHB 1RE0B 1QC7A 4JXHA 4Z21A 1PBVA 1XSZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SWV A;  1R8M E;  1R8Q E;  1XSZ A;  4JMI A;  4C0A A;  1BC9 A;  4D7Q A;  1KU1 A;  1S9D E;  4A4P A;  1XT0 B;  3L8N A;  4OIY A;  1R8S E;  2R09 A;  4L5M A;  4C7P A;  4JWL A;  3LTL A;  4D7R A;  2R0D A;  1RE0 B;  4JXH A;  4Z21 A;  1PBV A;  4JMO A; 
#chains in the Genus database with same CATH topology
 2VXG A;  1A8B A;  1PCM X;  5BMP A;  1UT4 A;  3OST A;  2QRC A;  1LWV A;  2NVM A;  1QTS A;  2IE7 A;  1C1K A;  1R8S E;  4WXA A;  1BCW A;  1N41 A;  4Q11 A;  1BCZ A;  2JHJ A;  4Q2S A;  3PMG A;  1LKV X;  2EHB D;  1AVH A;  5IYC P;  2HL8 A;  2HYW A;  2YH5 A;  2II2 A;  5EPC A;  1EUV A;  1ANW A;  2HKP A;  2Y8Q A;  1R4A E;  4EAK A;  3I0X A;  1PVS A;  1AII A;  3OH6 A;  1M3H A;  4OIY A;  1QNC A;  4FHR B;  3ENC A;  3CWU A;  3RPJ A;  1N00 A;  1BC3 A;  1YQM A;  1HU0 A;  1K35 A;  3ENO C;  4C0A A;  4EJZ A;  2V8Q A;  3CWS A;  1G5N A;  2V9J A;  1B9K A;  1M5Q 1;  2H5A X;  4MRQ A;  2YA3 A;  3OC3 C;  2HL9 A;  1KO9 A;  1YTB A;  1PBV A;  1M3Q A;  2NOL A;  2NLV A;  2MZ8 A;  1QTP A;  1NGM A;  2ZHI A;  2Z8U A;  1QNE A;  2OY9 A;  2D0B A;  3F10 A;  1TBP A;  1A8A A;  1BC1 A;  3ABQ A;  1K2Y X;  2ZOC A;  3HS9 A;  2FKF A;  1DK5 A;  1P5G X;  2Z0F A;  5JMV D;  1AIS A;  1LXT A;  1BC0 A;  1WJW A;  3SOH B;  1QN4 A;  2FGT A;  1KY7 A;  3OGD A;  1R4X A;  1R8Q E;  1EBM A;  1YQR A;  1QN6 A;  3SNS A;  2OOX A;  3H1Z A;  1QN5 A;  2JHN A;  1HVE A;  3AO0 A;  2JOI A;  4C7P A;  4EAJ A;  2NOH A;  4D7R A;  3CWT A;  1AVC A;  1V5S A;  3BKQ X;  1AOW A;  1W7B A;  2DKC A;  2O3O A;  3EIK A;  2VJ0 A;  2HZS A;  1VOL B;  3ULX A;  3RSM A;  3TE5 A;  2H0K A;  4EAL A;  3AJC A;  1ANN A;  4I8O A;  2NOB A;  3UW2 A;  2IV9 A;  1AXN A;  1J3M A;  2QEZ A;  3I0W A;  1C9B B;  1KFQ A;  2XO2 A;  1R8M E;  2NOF A;  1BO9 A;  4X9P A;  4PY5 A;  1KY6 A;  1QN3 A;  4HJH A;  3TDH A;  3OLP A;  4L5M A;  5IYB P;  1QNA A;  1DIZ A;  2Q4C A;  3OSM A;  5KL0 A;  2R0D A;  1XSZ A;  2IV8 A;  4HRE A;  2D0A A;  3CW7 A;  2D0C A;  1XJL A;  2QRD A;  1VTL E;  1JFI C;  2V92 A;  3L8N A;  2MJ7 A;  4EAI A;  3N89 A;  1YTF A;  3USY A;  3ABR A;  5IYD P;  3LTL A;  1N3C A;  1HVG A;  1M9I A;  1PCJ X;  2HYV A;  1QN7 A;  5JN5 A;  3ABS A;  1HM6 A;  3BRX A;  1UT7 A;  4ROC B;  3HJL A;  1Q8D A;  3OH9 A;  2DKD A;  3USW A;  2IIC A;  3KRM A;  2NOZ A;  1PCZ A;  1N44 A;  3IH7 A;  1QN8 A;  1QN9 A;  5HSH A;  1VTO A;  3CVS A;  2QLV A;  4KN7 X;  1TGH A;  4JMI A;  3OCI A;  1TUO A;  1CDW A;  3CWA A;  1I4A A;  2I5W A;  4B0A A;  4WX8 A;  1ANX A;  3T4N A;  1KFI A;  1DM5 A;  2ZHJ A;  4JXH A;  4ROD B;  2HSN A;  3I3W A;  3OSE A;  2NOI A;  2R5X A;  2H4L X;  2HZM A;  2XHI A;  1BCY A;  2OOY A;  4EAG A;  3ANY A;  1FN7 A;  1MCX A;  1RE0 B;  1AVR A;  2DKA A;  2QR1 A;  3F0Z A;  1YQL A;  3DPU A;  2IE6 A;  2JPI A;  2HYU A;  5F9C A;  1T6A A;  3D4V A;  4EJY A;  4TPS A;  1N3A A;  1NVP A;  2RAN A;  4QG5 A;  1HAK A;  2LAE A;  1N42 A;  4EVF A;  3KTU A;  1C47 A;  2NWV A;  1C4G A;  1QNB A;  4BJU A;  4KMU X;  4IL8 A;  4JK1 X;  2F7L A;  1SAV A;  3DPT A;  1BC9 A;  1YJ0 A;  4ROE B;  1S9D E;  4A4P A;  1LWW A;  4MDU A;  1N39 A;  3NA5 A;  4MDV A;  3D7Q A;  4JWL A;  1W3W A;  4Z21 A;  2H0L A;  3ASM A;  1TBA B;  1HVD A;  1LWY A;  1XT0 B;  2PWW A;  1Q9U A;  1P5D X;  1MPG A;  1KYU A;  1YII A;  1JDY A;  4D7Q A;  4JMO A;  2H0M A;  1E42 A;  1PZD A;  4KN4 X;  4DUL A;  1YGM A;  1KU1 A;  1VOK A;  1WQA A;  1W80 A;  1ALA A;  2FUV A;  3VN5 A;  5BMN A;  2Y8L A;  3C04 A;  2QRE A;  1YCN A;  1UL7 A;  2K6X A;  3ABO A;  2NOE A;  1QC7 A;  1VKL A;  1KYD A;  4WZS D;  1YQK A;  3SWV A;  4EVH A;  2ZFD B;  1NH2 A;  5AN4 A;  3PDK A;  4CFF A;  2XO3 A;  3CVT A;  1HVF A;  3TW5 A;  1MP9 A;  4FQ0 C;  1W45 A;  2FKM X;  2G30 A;  1UPT B;  1RM1 A;  1D3U A;  2R09 A;  3EAY A;  3HS8 A;  1KYF A;  1AEI A; 
#chains in the Genus database with same CATH homology
 2HSN A;  4KMU X;  3SWV A;  1R8M E;  4JK1 X;  1R8Q E;  4KN7 X;  3HJL A;  1Q8D A;  4JMI A;  4KN4 X;  4C0A A;  3TW5 A;  1BC9 A;  3USW A;  4D7Q A;  1KU1 A;  4FQ0 C;  4JMO A;  1S9D E;  4A4P A;  1XT0 B;  3L8N A;  3AJC A;  4OIY A;  1R8S E;  2R09 A;  4FHR B;  4L5M A;  4C7P A;  3USY A;  1LKV X;  4JWL A;  3LTL A;  4D7R A;  2K6X A;  2R0D A;  3SOH B;  1RE0 B;  1QC7 A;  4JXH A;  4Z21 A;  1PBV A;  1XSZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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