4C7PA

Crystal structure of legionella pneumophila ralf f255k mutant
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
347
structure length
347
Chain Sequence
SHPEIEKAQREIIEAFNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQVLKAFTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAAYLLAFQTIMLNTDLHNPSIPEKNKMTVDGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPFELNFVKTSPGYELTSTTLNKDSTFKKLDSFLHSTDVNINTVFPGIGDNVKTTVDQPKSWLSFKTGYKGTITLTDNKTSAQATIQVYTPNIFSKWLFGEQPRVIIQPGQTKESIDLAAKAAADFSSPVKNFKATYDYEVGDLIKAYDNQKKLITIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Membrane Sensor Controls the Localization and Arfgef Activity of Bacterial Ralf.
pubmed doi rcsb
molecule tags Signaling protein
source organism Legionella pneumophila
molecule keywords RALF
total genus 119
structure length 347
sequence length 347
ec nomenclature
pdb deposition date 2013-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01369 Sec7 Sec7 domain
A PF18248 RalF_SCD RalF C-terminal Sec-7 capping domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 4c7pA01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 4c7pA02
3.30.310.140 Alpha Beta 2-Layer Sandwich TATA-Binding Protein sec7 domains 4c7pA03
4L5MA 4D7QA 1S9DE 3LTLA 4OIYA 1XT0B 4D7RA 3SWVA 4JMOA 1BC9A 1R8QE 2R09A 4JMIA 4A4PA 4C0AA 4JWLA 1PBVA 1KU1A 4JXHA 1R8SE 2R0DA 4Z21A 1R8ME 3L8NA 1RE0B 4C7PA 1XSZA
chains in the Genus database with same CATH superfamily
4EAIA 1PCZA 3ASMA 4CFFA 1S9DE 1K2YX 2ZHIA 3H1ZA 1LXTA 3OC3C 3OLPA 2VXGA 1KFIA 1AOWA 1YQRA 2NVMA 2QLVA 3L8NA 1BC1A 2ZFDB 2NOZA 1QNBA 1QN6A 1JFIC 2V92A 4MDVA 4ROEB 3AJCA 2OOXA 2FGTA 3CW7A 4JMIA 4A4PA 2PWWA 4JWLA 3KTUA 3RPJA 4EJZA 2Z0FA 5BMNA 2XHIA 2NOHA 1BCWA 2QR1A 3ENOC 1WQAA 1RM1A 4BJUA 4D7QA 2G30A 1AIIA 1EUVA 1WJWA 1V5SA 1MPGA 1R8QE 1T6AA 4I8OA 1C47A 1HAKA 4X9PA 1YGMA 4Q2SA 2D0BA 1P5GX 2Y8QA 3OH9A 1LWWA 5IYBP 1YQKA 1M3QA 4WZSD 2Z8UA 3OSTA 1BO9A 2NWVA 2K6XA 2HL9A 2V9JA 3N89A 1A8BA 2H4LX 1PZDA 1LWVA 2IE6A 1QN7A 1PCMX 1QNCA 2HL8A 3CVTA 1ALAA 1UL7A 4IL8A 2F7LA 2H0LA 2YA3A 1QTSA 4KMUX 4OIYA 4RODB 5JMVD 2OOYA 1AEIA 2R09A 3D7QA 3NA5A 3ENCA 4TPSA 4KN7X 1HVDA 1N3CA 2MZ8A 1TBPA 3TDHA 4Q11A 1D3UA 1DIZA 1I4AA 2JHJA 3CWAA 5AN4A 3USYA 3EIKA 1UPTB 1HVGA 2EHBD 2XO2A 3F10A 1QC7A 2HZMA 2OY9A 3BRXA 3ULXA 1XJLA 2O3OA 5JN5A 1KYUA 1EBMA 4WX8A 2V8QA 1N42A 1AISA 3EAYA 4KN4X 1XT0B 4ROCB 3SWVA 2NOFA 3ABQA 1BC9A 2HYUA 1KY6A 1VTOA 1PCJX 4EAJA 3PMGA 3T4NA 1N44A 2QRDA 1SAVA 2HYWA 4DULA 1LWYA 1W7BA 1R8ME 2H0MA 2QEZA 2JOIA 4MRQA 3TE5A 2NLVA 4D7RA 1KYDA 1AVCA 3I3WA 3VN5A 2JHNA 1CDWA 2DKCA 1Q8DA 1PBVA 4EAGA 3TW5A 2D0CA 3OSEA 1YQMA 2R0DA 1FN7A 1VKLA 1C1KA 1TBAB 3PDKA 2DKAA 5HSHA 1W45A 3ABOA 2FKMX 3LTLA 2LAEA 3ABRA 3I0XA 2I5WA 4EVFA 4JMOA 3F0ZA 3OH6A 1BCZA 3CVSA 2NOLA 1YQLA 1TGHA 4JK1X 1QN5A 3USWA 1YJ0A 4PY5A 3CWTA 1HU0A 5IYCP 2XO3A 1QN9A 4L5MA 3HS9A 2ZHJA 1ANWA 3C04A 1R4XA 1HVFA 2JPIA 3AO0A 1NH2A 1W3WA 3D4VA 2D0AA 1HM6A 1KU1A 1QTPA 1C9BB 2QRCA 2ZOCA 1QNEA 3DPTA 2HYVA 2NOIA 3ANYA 4MDUA 1PVSA 1VTLE 1M9IA 5F9CA 1E42A 5BMPA 1N41A 4EAKA 5IYDP 4C0AA 3OSMA 1M5Q1 1W80A 1N39A 3DPUA 4Z21A 3IH7A 4C7PA 3I0WA 2RANA 4QG5A 2R5XA 1KY7A 1DK5A 1NGMA 3KRMA 1DM5A 1N00A 1G5NA 1K35A 2NOEA 2MJ7A 4HREA 1MCXA 3ABSA 1A8AA 2HZSA 4HJHA 1LKVX 1MP9A 1UT4A 1YIIA 2Y8LA 1AVHA 1BC3A 1R4AE 3HJLA 1AVRA 4EJYA 1NVPA 1UT7A 1QNAA 1N3AA 1YTBA 5EPCA 4JXHA 1R8SE 3RSMA 2H5AX 1B9KA 1Q9UA 2VJ0A 1RE0B 3UW2A 4EVHA 2HKPA 1QN4A 1TUOA 4FHRB 3OCIA 1KFQA 1QN8A 2YH5A 3OGDA 2IV8A 4WXAA 2IE7A 3BKQX 1M3HA 1BC0A 2H0KA 2NOBA 2Q4CA 3SNSA 1KO9A 1VOLB 2FUVA 2II2A 2IICA 1QN3A 1BCYA 3SOHB 1C4GA 1AXNA 3CWSA 3CWUA 1KYFA 2DKDA 1XSZA 1ANNA 2QREA 4FQ0C 5KL0A 4B0AA 1J3MA 3HS8A 2HSNA 1VOKA 1YCNA 4EALA 1ANXA 2IV9A 1YTFA 1JDYA 1P5DX 2FKFA 1HVEA
chains in the Genus database with same CATH topology
4KN4X 4L5MA 2K6XA 4D7QA 1S9DE 4FQ0C 3USYA 3LTLA 4OIYA 3AJCA 1XT0B 4FHRB 4D7RA 3HJLA 3SWVA 4JMOA 1BC9A 1R8QE 2HSNA 2R09A 4JMIA 4A4PA 4C0AA 3SOHB 4JWLA 1Q8DA 4JK1X 1PBVA 1QC7A 4KN7X 3TW5A 1KU1A 4JXHA 3USWA 1R8SE 2R0DA 4Z21A 1R8ME 3L8NA 1RE0B 1LKVX 4C7PA 4KMUX 1XSZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L5M A;  4D7Q A;  1S9D E;  3LTL A;  4OIY A;  1XT0 B;  4D7R A;  3SWV A;  4JMO A;  1BC9 A;  1R8Q E;  2R09 A;  4JMI A;  4A4P A;  4C0A A;  4JWL A;  1PBV A;  1KU1 A;  4JXH A;  1R8S E;  2R0D A;  4Z21 A;  1R8M E;  3L8N A;  1RE0 B;  4C7P A;  1XSZ A; 
#chains in the Genus database with same CATH topology
 4EAI A;  1PCZ A;  3ASM A;  4CFF A;  1S9D E;  1K2Y X;  2ZHI A;  3H1Z A;  1LXT A;  3OC3 C;  3OLP A;  2VXG A;  1KFI A;  1AOW A;  1YQR A;  2NVM A;  2QLV A;  3L8N A;  1BC1 A;  2ZFD B;  2NOZ A;  1QNB A;  1QN6 A;  1JFI C;  2V92 A;  4MDV A;  4ROE B;  3AJC A;  2OOX A;  2FGT A;  3CW7 A;  4JMI A;  4A4P A;  2PWW A;  4JWL A;  3KTU A;  3RPJ A;  4EJZ A;  2Z0F A;  5BMN A;  2XHI A;  2NOH A;  1BCW A;  2QR1 A;  3ENO C;  1WQA A;  1RM1 A;  4BJU A;  4D7Q A;  2G30 A;  1AII A;  1EUV A;  1WJW A;  1V5S A;  1MPG A;  1R8Q E;  1T6A A;  4I8O A;  1C47 A;  1HAK A;  4X9P A;  1YGM A;  4Q2S A;  2D0B A;  1P5G X;  2Y8Q A;  3OH9 A;  1LWW A;  5IYB P;  1YQK A;  1M3Q A;  4WZS D;  2Z8U A;  3OST A;  1BO9 A;  2NWV A;  2K6X A;  2HL9 A;  2V9J A;  3N89 A;  1A8B A;  2H4L X;  1PZD A;  1LWV A;  2IE6 A;  1QN7 A;  1PCM X;  1QNC A;  2HL8 A;  3CVT A;  1ALA A;  1UL7 A;  4IL8 A;  2F7L A;  2H0L A;  2YA3 A;  1QTS A;  4KMU X;  4OIY A;  4ROD B;  5JMV D;  2OOY A;  1AEI A;  2R09 A;  3D7Q A;  3NA5 A;  3ENC A;  4TPS A;  4KN7 X;  1HVD A;  1N3C A;  2MZ8 A;  1TBP A;  3TDH A;  4Q11 A;  1D3U A;  1DIZ A;  1I4A A;  2JHJ A;  3CWA A;  5AN4 A;  3USY A;  3EIK A;  1UPT B;  1HVG A;  2EHB D;  2XO2 A;  3F10 A;  1QC7 A;  2HZM A;  2OY9 A;  3BRX A;  3ULX A;  1XJL A;  2O3O A;  5JN5 A;  1KYU A;  1EBM A;  4WX8 A;  2V8Q A;  1N42 A;  1AIS A;  3EAY A;  4KN4 X;  1XT0 B;  4ROC B;  3SWV A;  2NOF A;  3ABQ A;  1BC9 A;  2HYU A;  1KY6 A;  1VTO A;  1PCJ X;  4EAJ A;  3PMG A;  3T4N A;  1N44 A;  2QRD A;  1SAV A;  2HYW A;  4DUL A;  1LWY A;  1W7B A;  1R8M E;  2H0M A;  2QEZ A;  2JOI A;  4MRQ A;  3TE5 A;  2NLV A;  4D7R A;  1KYD A;  1AVC A;  3I3W A;  3VN5 A;  2JHN A;  1CDW A;  2DKC A;  1Q8D A;  1PBV A;  4EAG A;  3TW5 A;  2D0C A;  3OSE A;  1YQM A;  2R0D A;  1FN7 A;  1VKL A;  1C1K A;  1TBA B;  3PDK A;  2DKA A;  5HSH A;  1W45 A;  3ABO A;  2FKM X;  3LTL A;  2LAE A;  3ABR A;  3I0X A;  2I5W A;  4EVF A;  4JMO A;  3F0Z A;  3OH6 A;  1BCZ A;  3CVS A;  2NOL A;  1YQL A;  1TGH A;  4JK1 X;  1QN5 A;  3USW A;  1YJ0 A;  4PY5 A;  3CWT A;  1HU0 A;  5IYC P;  2XO3 A;  1QN9 A;  4L5M A;  3HS9 A;  2ZHJ A;  1ANW A;  3C04 A;  1R4X A;  1HVF A;  2JPI A;  3AO0 A;  1NH2 A;  1W3W A;  3D4V A;  2D0A A;  1HM6 A;  1KU1 A;  1QTP A;  1C9B B;  2QRC A;  2ZOC A;  1QNE A;  3DPT A;  2HYV A;  2NOI A;  3ANY A;  4MDU A;  1PVS A;  1VTL E;  1M9I A;  5F9C A;  1E42 A;  5BMP A;  1N41 A;  4EAK A;  5IYD P;  4C0A A;  3OSM A;  1M5Q 1;  1W80 A;  1N39 A;  3DPU A;  4Z21 A;  3IH7 A;  4C7P A;  3I0W A;  2RAN A;  4QG5 A;  2R5X A;  1KY7 A;  1DK5 A;  1NGM A;  3KRM A;  1DM5 A;  1N00 A;  1G5N A;  1K35 A;  2NOE A;  2MJ7 A;  4HRE A;  1MCX A;  3ABS A;  1A8A A;  2HZS A;  4HJH A;  1LKV X;  1MP9 A;  1UT4 A;  1YII A;  2Y8L A;  1AVH A;  1BC3 A;  1R4A E;  3HJL A;  1AVR A;  4EJY A;  1NVP A;  1UT7 A;  1QNA A;  1N3A A;  1YTB A;  5EPC A;  4JXH A;  1R8S E;  3RSM A;  2H5A X;  1B9K A;  1Q9U A;  2VJ0 A;  1RE0 B;  3UW2 A;  4EVH A;  2HKP A;  1QN4 A;  1TUO A;  4FHR B;  3OCI A;  1KFQ A;  1QN8 A;  2YH5 A;  3OGD A;  2IV8 A;  4WXA A;  2IE7 A;  3BKQ X;  1M3H A;  1BC0 A;  2H0K A;  2NOB A;  2Q4C A;  3SNS A;  1KO9 A;  1VOL B;  2FUV A;  2II2 A;  2IIC A;  1QN3 A;  1BCY A;  3SOH B;  1C4G A;  1AXN A;  3CWS A;  3CWU A;  1KYF A;  2DKD A;  1XSZ A;  1ANN A;  2QRE A;  4FQ0 C;  5KL0 A;  4B0A A;  1J3M A;  3HS8 A;  2HSN A;  1VOK A;  1YCN A;  4EAL A;  1ANX A;  2IV9 A;  1YTF A;  1JDY A;  1P5D X;  2FKF A;  1HVE A; 
#chains in the Genus database with same CATH homology
 4KN4 X;  4L5M A;  2K6X A;  4D7Q A;  1S9D E;  4FQ0 C;  3USY A;  3LTL A;  4OIY A;  3AJC A;  1XT0 B;  4FHR B;  4D7R A;  3HJL A;  3SWV A;  4JMO A;  1BC9 A;  1R8Q E;  2HSN A;  2R09 A;  4JMI A;  4A4P A;  4C0A A;  3SOH B;  4JWL A;  1Q8D A;  4JK1 X;  1PBV A;  1QC7 A;  4KN7 X;  3TW5 A;  1KU1 A;  4JXH A;  3USW A;  1R8S E;  2R0D A;  4Z21 A;  1R8M E;  3L8N A;  1RE0 B;  1LKV X;  4C7P A;  4KMU X;  1XSZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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