4C7PA

Crystal structure of legionella pneumophila ralf f255k mutant
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
347
structure length
347
Chain Sequence
SHPEIEKAQREIIEAFNAKPKNGINKIKEICEQYKISPNEEIAEFFHQQRKNLDLEAVGDYLSSPEAENQQVLKAFTSQMNFNGQSFVEGLRTFLKTFKLPGEAQKIDRLVQSFSGAYFQQNPDVVSNADAAYLLAFQTIMLNTDLHNPSIPEKNKMTVDGLKRNLRGGNNGGDFDAKFLEELYSEIKAKPFELNFVKTSPGYELTSTTLNKDSTFKKLDSFLHSTDVNINTVFPGIGDNVKTTVDQPKSWLSFKTGYKGTITLTDNKTSAQATIQVYTPNIFSKWLFGEQPRVIIQPGQTKESIDLAAKAAADFSSPVKNFKATYDYEVGDLIKAYDNQKKLITIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Membrane Sensor Controls the Localization and Arfgef Activity of Bacterial Ralf.
pubmed doi rcsb
molecule tags Signaling protein
source organism Legionella pneumophila
molecule keywords RALF
total genus 119
structure length 347
sequence length 347
ec nomenclature
pdb deposition date 2013-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01369 Sec7 Sec7 domain
A PF18248 RalF_SCD RalF C-terminal Sec-7 capping domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.20 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin V; domain 1 4c7pA01
1.10.1000.11 Mainly Alpha Orthogonal Bundle Arf Nucleotide-binding Site Opener; domain 2 Arf Nucleotide-binding Site Opener,domain 2 4c7pA02
3.30.310.140 Alpha Beta 2-Layer Sandwich TATA-Binding Protein sec7 domains 4c7pA03
4JMIA 4Z21A 4JMOA 4D7QA 4JXHA 1XSZA 1RE0B 2R0DA 4L5MA 1BC9A 4JWLA 4C7PA 3SWVA 4OIYA 1R8SE 3LTLA 1KU1A 4A4PA 1S9DE 3L8NA 4C0AA 2R09A 1R8QE 1XT0B 4D7RA 1R8ME 1PBVA
chains in the Genus database with same CATH superfamily
3ANYA 4EVHA 2EHBD 1QN8A 4PY5A 1KU1A 1XJLA 1BC1A 2HL8A 1AVRA 4MDUA 2IICA 3ULXA 1KFIA 1TGHA 4D7RA 2XHIA 1M3QA 3CW7A 2QLVA 3CWSA 2K6XA 3KTUA 4L5MA 3AO0A 2HSNA 3NA5A 4BJUA 1S9DE 2IV9A 3OC3C 4ROEB 1KFQA 1PCJX 3KRMA 2VJ0A 4FQ0C 2ZFDB 2XO3A 2LAEA 3ABOA 4EJZA 2MZ8A 2Z0FA 1LKVX 1QN7A 3USWA 2OOYA 4I8OA 1CDWA 4WZSD 2IE7A 1SAVA 1R8QE 1M3HA 2NOIA 3SOHB 1I4AA 1BC0A 1N3AA 2JHJA 2II2A 1V5SA 1C9BB 3BRXA 3OSMA 4D7QA 1MPGA 1TBPA 5IYDP 1LXTA 2YH5A 1ANNA 4B0AA 1DIZA 1HM6A 2DKAA 1YQKA 1E42A 1VKLA 3DPTA 1EUVA 2VXGA 4JMIA 4RODB 2IV8A 3F0ZA 1QNAA 3OSEA 2V9JA 2O3OA 1WQAA 2NOHA 3BKQX 2PWWA 3HJLA 3N89A 5EPCA 4JK1X 1LWVA 2NOBA 2R09A 1RM1A 2HYWA 1KY7A 1EBMA 1ANXA 1XT0B 2ZOCA 2I5WA 1QC7A 2FGTA 4EAKA 3OSTA 1QN4A 3UW2A 1QN6A 4CFFA 2Q4CA 3LTLA 1JFIC 1TBAB 4EALA 1UT7A 3TW5A 1N00A 4IL8A 3T4NA 1BC3A 1QNEA 4KN7X 3F10A 1K2YX 1N42A 1NVPA 1FN7A 1BC9A 4JWLA 1NH2A 3EIKA 1QTSA 3HS8A 1HVGA 1VOLB 1DK5A 3CVTA 1KYDA 2H0MA 3DPUA 3EAYA 1YQLA 1LWWA 1R4AE 1PZDA 1AVHA 2XO2A 4MDVA 2OOXA 1AVCA 5HSHA 1AOWA 2NLVA 2R5XA 4EAIA 1Q8DA 2ZHIA 1BCYA 2IE6A 1YTFA 5JMVD 5BMNA 1M5Q1 3IH7A 1D3UA 1P5DX 1R8ME 1N44A 1K35A 2H4LX 2QRDA 2F7LA 2V92A 1VTLE 2FKMX 1KYUA 3I0XA 2RANA 3OCIA 3TE5A 5IYCP 4C7PA 1AXNA 1R8SE 2HL9A 3VN5A 4EAJA 3CWUA 1T6AA 4EJYA 1Q9UA 2NOFA 4ROCB 4KMUX 1W80A 2FKFA 2NWVA 1HAKA 2DKDA 2V8QA 1QNCA 1ANWA 3I0WA 5F9CA 1NGMA 1B9KA 1YTBA 1J3MA 1AIIA 1AISA 2H0KA 3OH9A 4DULA 1TUOA 1G5NA 1KO9A 4EVFA 1DM5A 3PDKA 1PCZA 2R0DA 2H5AX 3H1ZA 1UT4A 4C0AA 4EAGA 1YJ0A 2H0LA 3SNSA 1BCZA 1YQRA 1N39A 5AN4A 1C47A 4JMOA 2Y8QA 2NOEA 2MJ7A 4HREA 2JOIA 4HJHA 1QTPA 5BMPA 3L8NA 2HKPA 2QR1A 2NVMA 2D0BA 4TPSA 2FUVA 2QREA 3RSMA 5JN5A 1C1KA 4WX8A 2NOZA 5KL0A 3CWAA 1QN3A 2QEZA 2ZHJA 1XSZA 4WXAA 3TDHA 1MCXA 4MRQA 1YGMA 3D7QA 1AEIA 2HYUA 4A4PA 1JDYA 2Y8LA 1HVDA 3OH6A 2OY9A 2JPIA 3OLPA 4Q2SA 1PVSA 2HZSA 1KYFA 3ENCA 3ABQA 3PMGA 2D0CA 4OIYA 3USYA 1HU0A 3ENOC 3ABRA 1A8AA 3ASMA 1N3CA 3CWTA 1W3WA 1YCNA 1WJWA 1QN5A 1ALAA 2G30A 2YA3A 4Z21A 1W7BA 1A8BA 2JHNA 2QRCA 1YIIA 1VOKA 4JXHA 3I3WA 1KY6A 4Q11A 1BCWA 1RE0B 1UL7A 3OGDA 1QN9A 1W45A 3C04A 2HZMA 3SWVA 1R4XA 5IYBP 1LWYA 1N41A 3HS9A 1VTOA 1HVFA 1UPTB 1YQMA 3ABSA 4FHRB 4KN4X 1PCMX 4QG5A 3D4VA 3RPJA 3AJCA 1QNBA 1M9IA 1HVEA 4X9PA 2DKCA 1BO9A 1P5GX 2D0AA 3CVSA 2Z8UA 1MP9A 2NOLA 1C4GA 2HYVA 1PBVA
chains in the Genus database with same CATH topology
4JMIA 4Z21A 4FHRB 4KN4X 1QC7A 4JMOA 4KN7X 3AJCA 2K6XA 4D7QA 4JXHA 1LKVX 1XSZA 1RE0B 2R0DA 4L5MA 1BC9A 4JWLA 2HSNA 4C7PA 3USWA 4FQ0C 4OIYA 3SWVA 1R8SE 3HJLA 1KU1A 3LTLA 3USYA 4A4PA 1S9DE 3L8NA 1Q8DA 4JK1X 4C0AA 2R09A 1R8QE 3TW5A 1XT0B 4D7RA 4KMUX 3SOHB 1R8ME 1PBVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JMI A;  4Z21 A;  4JMO A;  4D7Q A;  4JXH A;  1XSZ A;  1RE0 B;  2R0D A;  4L5M A;  1BC9 A;  4JWL A;  4C7P A;  3SWV A;  4OIY A;  1R8S E;  3LTL A;  1KU1 A;  4A4P A;  1S9D E;  3L8N A;  4C0A A;  2R09 A;  1R8Q E;  1XT0 B;  4D7R A;  1R8M E;  1PBV A; 
#chains in the Genus database with same CATH topology
 3ANY A;  4EVH A;  2EHB D;  1QN8 A;  4PY5 A;  1KU1 A;  1XJL A;  1BC1 A;  2HL8 A;  1AVR A;  4MDU A;  2IIC A;  3ULX A;  1KFI A;  1TGH A;  4D7R A;  2XHI A;  1M3Q A;  3CW7 A;  2QLV A;  3CWS A;  2K6X A;  3KTU A;  4L5M A;  3AO0 A;  2HSN A;  3NA5 A;  4BJU A;  1S9D E;  2IV9 A;  3OC3 C;  4ROE B;  1KFQ A;  1PCJ X;  3KRM A;  2VJ0 A;  4FQ0 C;  2ZFD B;  2XO3 A;  2LAE A;  3ABO A;  4EJZ A;  2MZ8 A;  2Z0F A;  1LKV X;  1QN7 A;  3USW A;  2OOY A;  4I8O A;  1CDW A;  4WZS D;  2IE7 A;  1SAV A;  1R8Q E;  1M3H A;  2NOI A;  3SOH B;  1I4A A;  1BC0 A;  1N3A A;  2JHJ A;  2II2 A;  1V5S A;  1C9B B;  3BRX A;  3OSM A;  4D7Q A;  1MPG A;  1TBP A;  5IYD P;  1LXT A;  2YH5 A;  1ANN A;  4B0A A;  1DIZ A;  1HM6 A;  2DKA A;  1YQK A;  1E42 A;  1VKL A;  3DPT A;  1EUV A;  2VXG A;  4JMI A;  4ROD B;  2IV8 A;  3F0Z A;  1QNA A;  3OSE A;  2V9J A;  2O3O A;  1WQA A;  2NOH A;  3BKQ X;  2PWW A;  3HJL A;  3N89 A;  5EPC A;  4JK1 X;  1LWV A;  2NOB A;  2R09 A;  1RM1 A;  2HYW A;  1KY7 A;  1EBM A;  1ANX A;  1XT0 B;  2ZOC A;  2I5W A;  1QC7 A;  2FGT A;  4EAK A;  3OST A;  1QN4 A;  3UW2 A;  1QN6 A;  4CFF A;  2Q4C A;  3LTL A;  1JFI C;  1TBA B;  4EAL A;  1UT7 A;  3TW5 A;  1N00 A;  4IL8 A;  3T4N A;  1BC3 A;  1QNE A;  4KN7 X;  3F10 A;  1K2Y X;  1N42 A;  1NVP A;  1FN7 A;  1BC9 A;  4JWL A;  1NH2 A;  3EIK A;  1QTS A;  3HS8 A;  1HVG A;  1VOL B;  1DK5 A;  3CVT A;  1KYD A;  2H0M A;  3DPU A;  3EAY A;  1YQL A;  1LWW A;  1R4A E;  1PZD A;  1AVH A;  2XO2 A;  4MDV A;  2OOX A;  1AVC A;  5HSH A;  1AOW A;  2NLV A;  2R5X A;  4EAI A;  1Q8D A;  2ZHI A;  1BCY A;  2IE6 A;  1YTF A;  5JMV D;  5BMN A;  1M5Q 1;  3IH7 A;  1D3U A;  1P5D X;  1R8M E;  1N44 A;  1K35 A;  2H4L X;  2QRD A;  2F7L A;  2V92 A;  1VTL E;  2FKM X;  1KYU A;  3I0X A;  2RAN A;  3OCI A;  3TE5 A;  5IYC P;  4C7P A;  1AXN A;  1R8S E;  2HL9 A;  3VN5 A;  4EAJ A;  3CWU A;  1T6A A;  4EJY A;  1Q9U A;  2NOF A;  4ROC B;  4KMU X;  1W80 A;  2FKF A;  2NWV A;  1HAK A;  2DKD A;  2V8Q A;  1QNC A;  1ANW A;  3I0W A;  5F9C A;  1NGM A;  1B9K A;  1YTB A;  1J3M A;  1AII A;  1AIS A;  2H0K A;  3OH9 A;  4DUL A;  1TUO A;  1G5N A;  1KO9 A;  4EVF A;  1DM5 A;  3PDK A;  1PCZ A;  2R0D A;  2H5A X;  3H1Z A;  1UT4 A;  4C0A A;  4EAG A;  1YJ0 A;  2H0L A;  3SNS A;  1BCZ A;  1YQR A;  1N39 A;  5AN4 A;  1C47 A;  4JMO A;  2Y8Q A;  2NOE A;  2MJ7 A;  4HRE A;  2JOI A;  4HJH A;  1QTP A;  5BMP A;  3L8N A;  2HKP A;  2QR1 A;  2NVM A;  2D0B A;  4TPS A;  2FUV A;  2QRE A;  3RSM A;  5JN5 A;  1C1K A;  4WX8 A;  2NOZ A;  5KL0 A;  3CWA A;  1QN3 A;  2QEZ A;  2ZHJ A;  1XSZ A;  4WXA A;  3TDH A;  1MCX A;  4MRQ A;  1YGM A;  3D7Q A;  1AEI A;  2HYU A;  4A4P A;  1JDY A;  2Y8L A;  1HVD A;  3OH6 A;  2OY9 A;  2JPI A;  3OLP A;  4Q2S A;  1PVS A;  2HZS A;  1KYF A;  3ENC A;  3ABQ A;  3PMG A;  2D0C A;  4OIY A;  3USY A;  1HU0 A;  3ENO C;  3ABR A;  1A8A A;  3ASM A;  1N3C A;  3CWT A;  1W3W A;  1YCN A;  1WJW A;  1QN5 A;  1ALA A;  2G30 A;  2YA3 A;  4Z21 A;  1W7B A;  1A8B A;  2JHN A;  2QRC A;  1YII A;  1VOK A;  4JXH A;  3I3W A;  1KY6 A;  4Q11 A;  1BCW A;  1RE0 B;  1UL7 A;  3OGD A;  1QN9 A;  1W45 A;  3C04 A;  2HZM A;  3SWV A;  1R4X A;  5IYB P;  1LWY A;  1N41 A;  3HS9 A;  1VTO A;  1HVF A;  1UPT B;  1YQM A;  3ABS A;  4FHR B;  4KN4 X;  1PCM X;  4QG5 A;  3D4V A;  3RPJ A;  3AJC A;  1QNB A;  1M9I A;  1HVE A;  4X9P A;  2DKC A;  1BO9 A;  1P5G X;  2D0A A;  3CVS A;  2Z8U A;  1MP9 A;  2NOL A;  1C4G A;  2HYV A;  1PBV A; 
#chains in the Genus database with same CATH homology
 4JMI A;  4Z21 A;  4FHR B;  4KN4 X;  1QC7 A;  4JMO A;  4KN7 X;  3AJC A;  2K6X A;  4D7Q A;  4JXH A;  1LKV X;  1XSZ A;  1RE0 B;  2R0D A;  4L5M A;  1BC9 A;  4JWL A;  2HSN A;  4C7P A;  3USW A;  4FQ0 C;  4OIY A;  3SWV A;  1R8S E;  3HJL A;  1KU1 A;  3LTL A;  3USY A;  4A4P A;  1S9D E;  3L8N A;  1Q8D A;  4JK1 X;  4C0A A;  2R09 A;  1R8Q E;  3TW5 A;  1XT0 B;  4D7R A;  4KMU X;  3SOH B;  1R8M E;  1PBV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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