1P4TA

Crystal structure of neisserial surface protein a (nspa)
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
155
structure length
155
Chain Sequence
EGASGFYVQADAAHAKASSSLGSAKGFSPRISAGYRINDLRFAVDYTRYKNYKAPSTDFKLYSIGASAIYDFDTQSPVKPYLGARLSLNRASVDLGGSDSFSQTSIGLGVLTGVSYAVTPNVDLDAGYRYNYIGKVNTVKNVRSGELSAGVRVKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Neisserial Surface Protein A (NspA), a conserved outer membrane protein with vaccine potential
pubmed doi rcsb
molecule tags Membrane protein
source organism Neisseria meningitidis
molecule keywords outer membrane protein NspA
total genus 40
structure length 155
sequence length 155
ec nomenclature
pdb deposition date 2003-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02462 Opacity Opacity family porin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.20 Mainly Beta Beta Barrel Porin Porin 1p4tA00
3G7GA 2LHFA 1BXWA 3C5OA 3QRAA 1MM4A 2N2LA 2M06A 3QRCA 1Q9FA 2M07A 3GP6A 2K0LA 2MHLA 2JMMA 2F1VA 2ERVA 1G90A 1ORMA 1QJ9A 2GE4A 4PUXA 1THQA 2N2MA 2X27X 4RLCA 2F1TA 1QJ8A 2MNHA 1Q9GA 1QJPA 1P4TA 1MM5A
chains in the Genus database with same CATH superfamily
3G7GA 5D5DA 5DL6A 1HXTA 1E54A 2XG6A 3NSGA 1BXWA 1OPFA 3LK2A 4AYNA 4E1SA 5JDPA 1BH3A 3DWOX 1GFQA 1GFMA 3QRAA 4GHBA 5ADXK 2PORA 3O0EA 2XE3A 4FZMA 2K0LA 1HXXA 3PQUA 5G38A 6PRNA 3JCUO 4FMSA 1T1LA 2ERVA 1IZNB 3AA7A 3DWNA 3KVDD 3PF1A 4FRTA 4FT6A 5DL5A 1QJ9A 5E79O 2OMFA 5GTIO 3VE2A 5G3AA 2Y0KA 3DA3A 4AYID 4C4VB 3AA6A 2KC0A 1YS5A 3AA0A 3AAEB 5PRNA 3AAAA 4G76A 3SYSA 4RJXA 1S5LO 3SZDA 1QJ8A 3T24A 3KZIO 2AXTO 3POXA 4LSEA 2ZFGA 2R8AA 2R4NA 2W81C 4QQ1A 2LFUA 1Q9GA 3DZMA 3PGUA 3PQSA 1QJPA 4FUVA 4Z3TA 4AKRB 2KDYA 2K4TA 2YNKA 1ZHZA 4LSHA 4FSPA 4GF4A 2R88A 2WJQA 1H6S1 2Y0HA 3AA1A 3C5OA 1MPFA 3HOLA 4FRXA 3VE1A 4BUMX 3QRCA 4D64A 8PRNA 4KR4A 4AKMA 2J4UP 3AA0B 4LSFA 2JMMA 5GV0A 2F1VA 1BT9A 1ZHWA 2KXPA 3BRZA 3PRNA 1G90A 1ORMA 3LK42 5DL7A 2GE4A 3SYBA 4KRAA 4PUXA 3POQA 4UB6O 3EMNX 2O4VA 4C00A 5H2FO 3LK3A 1T16A 2PRNA 3TZGA 4RJWA 3PGRA 3AA1B 3LK2B 3K19A 2XTQA 5KAFO 1GFOA 2Y2XA 4K3CA 4CTDA 4O3YA 7PRNA 4B61A 1MM5A 4FSOA 4FZLA 4F4BA 3VZTX 3A2SX 5KAIO 3DA4A 3NJTA 4FESA 3WI4A 3WU2O 4JCHA 5IYUA 2IWWA 3AA7B 2R89A 1ZHYA 3HOEA 4AYEC 1MM4A 2XE5A 4RL9A 4XNLA 3SY9A 2M06A 2XE1A 1Q9FA 3POUA 5B66O 3T20A 3GP6A 4N58A 4O4UA 3UPGA 2MHLA 4IL6O 3AA6B 3BS0A 1OSMA 2XE2A 3LK41 1GFPA 3AAAB 4PR7A 2ZLDA 4AZLA 4LSIA 3SY7A 2R4LA 2KZ7A 3VZUX 1THQA 3A0BO 4N59A 4UB8O 5T5FA 4XNKA 4RLCA 5G39A 4AYMC 4C69X 4N75A 1HXUA 1IZNA 3FYXA 4O3WA 4GCQA 5GTHO 3BRYA 2MNHA 2F1CX 4AYDC 5AFUL 2JQYA 3V8UA 3UAQA 2J1NA 4PJ0O 4E1TA 4G75A 3AAEA 2Y7SA 4O3ZA 1ZHXA 5G26A 2W80C 2LHFA 4O4XA 2FGQX 2XTRA 2KXPB 4FQEA 2KZ7B 3A0HO 3VY9X 2N2LA 3WI5A 5TISO 2WVPA 4KR8A 4AFKA 1ZHTA 2M07A 4AKRA 4D5UA 5B5EO 4O3XB 5EE2A 4FOZA 4AUIA 3PGSA 3RBHA 5ADXL 3LK3B 2YPVA 3HWBA 4FZNA 1PHOA 3VY8X 3HW9A 2ODJA 2X9KA 3PORA 3T0SA 2Y0LA 2WJRA 4GCPA 2N2MA 2X27X 3UU2A 4K3BA 2F1TA 4U9CA 3SZVA 5AFUK 5DL8A 2R4PA 2FGRA 4N74A 4RLBA 2QTKA 4JFBA 1PRNA 3JTYA 5FVNA 4D65A 2R4OA 2XMXA 4GCSA 3VZWX 4O49A 1P4TA 4C4VA 1GFNA 2IWVA
chains in the Genus database with same CATH topology
3G7GA 5D5DA 5DL6A 1HXTA 1E54A 2XG6A 3NSGA 1BXWA 1OPFA 3LK2A 4AYNA 4E1SA 5JDPA 1BH3A 4GHBA 1GFQA 1GFMA 3QRAA 5ADXK 2PORA 3O0EA 2XE3A 4FZMA 2K0LA 1HXXA 3PQUA 6PRNA 4FMSA 2ERVA 3AA7A 1IZNB 4FRTA 4FT6A 3KVDD 5DL5A 1QJ9A 2OMFA 3VE2A 2Y0KA 3DA3A 4AYID 3AA6A 2KC0A 1YS5A 3AA0A 3AAEB 5PRNA 3AAAA 4G76A 3SYSA 4RJXA 3SZDA 1QJ8A 3T24A 3POXA 4LSEA 2ZFGA 2W81C 4QQ1A 2LFUA 1Q9GA 3PQSA 4FUVA 1QJPA 4Z3TA 4AKRB 2KDYA 2K4TA 2YNKA 1ZHZA 4LSHA 4FSPA 4GF4A 1H6S1 2Y0HA 3AA1A 3C5OA 1MPFA 3HOLA 4FRXA 3VE1A 4BUMX 3QRCA 4D64A 8PRNA 4KR4A 4AKMA 2J4UP 3AA0B 4LSFA 2JMMA 5GV0A 2F1VA 1BT9A 1ZHWA 2KXPA 3PRNA 1G90A 1ORMA 3LK42 5DL7A 2GE4A 3SYBA 4KRAA 4PUXA 3EMNX 2O4VA 3LK3A 2PRNA 3TZGA 4RJWA 3AA1B 3LK2B 3K19A 2XTQA 7PRNA 1GFOA 2Y2XA 4O3YA 4B61A 1MM5A 4FSOA 4FZLA 4F4BA 3VZTX 3A2SX 3WI4A 3DA4A 4FESA 5IYUA 4JCHA 3AA7B 1ZHYA 3HOEA 4AYEC 1MM4A 2XE5A 4RL9A 4XNLA 3SY9A 2M06A 2XE1A 1Q9FA 3POUA 3T20A 3GP6A 4N58A 4O4UA 3UPGA 2MHLA 3AA6B 3LK41 1OSMA 2XE2A 1GFPA 3AAAB 2ZLDA 4AZLA 4LSIA 3SY7A 2KZ7A 3VZUX 1THQA 4N59A 5T5FA 4XNKA 4RLCA 4AYMC 4C69X 1HXUA 1IZNA 3FYXA 4O3WA 4GCQA 2MNHA 4AYDC 5AFUL 3V8UA 3UAQA 2J1NA 4E1TA 4G75A 3AAEA 2Y7SA 4O3ZA 1ZHXA 5G26A 2W80C 2LHFA 4O4XA 2FGQX 2XTRA 2KXPB 2KZ7B 3VY9X 2N2LA 3WI5A 4KR8A 4AFKA 4AKRA 1ZHTA 2M07A 4D5UA 4O3XB 5EE2A 4FOZA 4AUIA 3RBHA 5ADXL 3LK3B 2YPVA 3HWBA 4FZNA 1PHOA 3VY8X 3HW9A 2ODJA 3PORA 3T0SA 2Y0LA 4GCPA 2N2MA 2X27X 3UU2A 3SZVA 2F1TA 4U9CA 5AFUK 5DL8A 2FGRA 4RLBA 2QTKA 4JFBA 1PRNA 3JTYA 5FVNA 4D65A 3VZWX 2XMXA 4GCSA 4O49A 1P4TA 1GFNA 3POQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G7G A;  2LHF A;  1BXW A;  3C5O A;  3QRA A;  1MM4 A;  2N2L A;  2M06 A;  3QRC A;  1Q9F A;  2M07 A;  3GP6 A;  2K0L A;  2MHL A;  2JMM A;  2F1V A;  2ERV A;  1G90 A;  1ORM A;  1QJ9 A;  2GE4 A;  4PUX A;  1THQ A;  2N2M A;  2X27 X;  4RLC A;  2F1T A;  1QJ8 A;  2MNH A;  1Q9G A;  1QJP A;  1P4T A;  1MM5 A; 
#chains in the Genus database with same CATH topology
 3G7G A;  5D5D A;  5DL6 A;  1HXT A;  1E54 A;  2XG6 A;  3NSG A;  1BXW A;  1OPF A;  3LK2 A;  4AYN A;  4E1S A;  5JDP A;  1BH3 A;  3DWO X;  1GFQ A;  1GFM A;  3QRA A;  4GHB A;  5ADX K;  2POR A;  3O0E A;  2XE3 A;  4FZM A;  2K0L A;  1HXX A;  3PQU A;  5G38 A;  6PRN A;  3JCU O;  4FMS A;  1T1L A;  2ERV A;  1IZN B;  3AA7 A;  3DWN A;  3KVD D;  3PF1 A;  4FRT A;  4FT6 A;  5DL5 A;  1QJ9 A;  5E79 O;  2OMF A;  5GTI O;  3VE2 A;  5G3A A;  2Y0K A;  3DA3 A;  4AYI D;  4C4V B;  3AA6 A;  2KC0 A;  1YS5 A;  3AA0 A;  3AAE B;  5PRN A;  3AAA A;  4G76 A;  3SYS A;  4RJX A;  1S5L O;  3SZD A;  1QJ8 A;  3T24 A;  3KZI O;  2AXT O;  3POX A;  4LSE A;  2ZFG A;  2R8A A;  2R4N A;  2W81 C;  4QQ1 A;  2LFU A;  1Q9G A;  3DZM A;  3PGU A;  3PQS A;  1QJP A;  4FUV A;  4Z3T A;  4AKR B;  2KDY A;  2K4T A;  2YNK A;  1ZHZ A;  4LSH A;  4FSP A;  4GF4 A;  2R88 A;  2WJQ A;  1H6S 1;  2Y0H A;  3AA1 A;  3C5O A;  1MPF A;  3HOL A;  4FRX A;  3VE1 A;  4BUM X;  3QRC A;  4D64 A;  8PRN A;  4KR4 A;  4AKM A;  2J4U P;  3AA0 B;  4LSF A;  2JMM A;  5GV0 A;  2F1V A;  1BT9 A;  1ZHW A;  2KXP A;  3BRZ A;  3PRN A;  1G90 A;  1ORM A;  3LK4 2;  5DL7 A;  2GE4 A;  3SYB A;  4KRA A;  4PUX A;  3POQ A;  4UB6 O;  3EMN X;  2O4V A;  4C00 A;  5H2F O;  3LK3 A;  1T16 A;  2PRN A;  3TZG A;  4RJW A;  3PGR A;  3AA1 B;  3LK2 B;  3K19 A;  2XTQ A;  5KAF O;  1GFO A;  2Y2X A;  4K3C A;  4CTD A;  4O3Y A;  7PRN A;  4B61 A;  1MM5 A;  4FSO A;  4FZL A;  4F4B A;  3VZT X;  3A2S X;  5KAI O;  3DA4 A;  3NJT A;  4FES A;  3WI4 A;  3WU2 O;  4JCH A;  5IYU A;  2IWW A;  3AA7 B;  2R89 A;  1ZHY A;  3HOE A;  4AYE C;  1MM4 A;  2XE5 A;  4RL9 A;  4XNL A;  3SY9 A;  2M06 A;  2XE1 A;  1Q9F A;  3POU A;  5B66 O;  3T20 A;  3GP6 A;  4N58 A;  4O4U A;  3UPG A;  2MHL A;  4IL6 O;  3AA6 B;  3BS0 A;  1OSM A;  2XE2 A;  3LK4 1;  1GFP A;  3AAA B;  4PR7 A;  2ZLD A;  4AZL A;  4LSI A;  3SY7 A;  2R4L A;  2KZ7 A;  3VZU X;  1THQ A;  3A0B O;  4N59 A;  4UB8 O;  5T5F A;  4XNK A;  4RLC A;  5G39 A;  4AYM C;  4C69 X;  4N75 A;  1HXU A;  1IZN A;  3FYX A;  4O3W A;  4GCQ A;  5GTH O;  3BRY A;  2MNH A;  2F1C X;  4AYD C;  5AFU L;  2JQY A;  3V8U A;  3UAQ A;  2J1N A;  4PJ0 O;  4E1T A;  4G75 A;  3AAE A;  2Y7S A;  4O3Z A;  1ZHX A;  5G26 A;  2W80 C;  2LHF A;  4O4X A;  2FGQ X;  2XTR A;  2KXP B;  4FQE A;  2KZ7 B;  3A0H O;  3VY9 X;  2N2L A;  3WI5 A;  5TIS O;  2WVP A;  4KR8 A;  4AFK A;  1ZHT A;  2M07 A;  4AKR A;  4D5U A;  5B5E O;  4O3X B;  5EE2 A;  4FOZ A;  4AUI A;  3PGS A;  3RBH A;  5ADX L;  3LK3 B;  2YPV A;  3HWB A;  4FZN A;  1PHO A;  3VY8 X;  3HW9 A;  2ODJ A;  2X9K A;  3POR A;  3T0S A;  2Y0L A;  2WJR A;  4GCP A;  2N2M A;  2X27 X;  3UU2 A;  4K3B A;  2F1T A;  4U9C A;  3SZV A;  5AFU K;  5DL8 A;  2R4P A;  2FGR A;  4N74 A;  4RLB A;  2QTK A;  4JFB A;  1PRN A;  3JTY A;  5FVN A;  4D65 A;  2R4O A;  2XMX A;  4GCS A;  3VZW X;  4O49 A;  1P4T A;  4C4V A;  1GFN A;  2IWV A; 
#chains in the Genus database with same CATH homology
 3G7G A;  5D5D A;  5DL6 A;  1HXT A;  1E54 A;  2XG6 A;  3NSG A;  1BXW A;  1OPF A;  3LK2 A;  4AYN A;  4E1S A;  5JDP A;  1BH3 A;  4GHB A;  1GFQ A;  1GFM A;  3QRA A;  5ADX K;  2POR A;  3O0E A;  2XE3 A;  4FZM A;  2K0L A;  1HXX A;  3PQU A;  6PRN A;  4FMS A;  2ERV A;  3AA7 A;  1IZN B;  4FRT A;  4FT6 A;  3KVD D;  5DL5 A;  1QJ9 A;  2OMF A;  3VE2 A;  2Y0K A;  3DA3 A;  4AYI D;  3AA6 A;  2KC0 A;  1YS5 A;  3AA0 A;  3AAE B;  5PRN A;  3AAA A;  4G76 A;  3SYS A;  4RJX A;  3SZD A;  1QJ8 A;  3T24 A;  3POX A;  4LSE A;  2ZFG A;  2W81 C;  4QQ1 A;  2LFU A;  1Q9G A;  3PQS A;  4FUV A;  1QJP A;  4Z3T A;  4AKR B;  2KDY A;  2K4T A;  2YNK A;  1ZHZ A;  4LSH A;  4FSP A;  4GF4 A;  1H6S 1;  2Y0H A;  3AA1 A;  3C5O A;  1MPF A;  3HOL A;  4FRX A;  3VE1 A;  4BUM X;  3QRC A;  4D64 A;  8PRN A;  4KR4 A;  4AKM A;  2J4U P;  3AA0 B;  4LSF A;  2JMM A;  5GV0 A;  2F1V A;  1BT9 A;  1ZHW A;  2KXP A;  3PRN A;  1G90 A;  1ORM A;  3LK4 2;  5DL7 A;  2GE4 A;  3SYB A;  4KRA A;  4PUX A;  3EMN X;  2O4V A;  3LK3 A;  2PRN A;  3TZG A;  4RJW A;  3AA1 B;  3LK2 B;  3K19 A;  2XTQ A;  7PRN A;  1GFO A;  2Y2X A;  4O3Y A;  4B61 A;  1MM5 A;  4FSO A;  4FZL A;  4F4B A;  3VZT X;  3A2S X;  3WI4 A;  3DA4 A;  4FES A;  5IYU A;  4JCH A;  3AA7 B;  1ZHY A;  3HOE A;  4AYE C;  1MM4 A;  2XE5 A;  4RL9 A;  4XNL A;  3SY9 A;  2M06 A;  2XE1 A;  1Q9F A;  3POU A;  3T20 A;  3GP6 A;  4N58 A;  4O4U A;  3UPG A;  2MHL A;  3AA6 B;  3LK4 1;  1OSM A;  2XE2 A;  1GFP A;  3AAA B;  2ZLD A;  4AZL A;  4LSI A;  3SY7 A;  2KZ7 A;  3VZU X;  1THQ A;  4N59 A;  5T5F A;  4XNK A;  4RLC A;  4AYM C;  4C69 X;  1HXU A;  1IZN A;  3FYX A;  4O3W A;  4GCQ A;  2MNH A;  4AYD C;  5AFU L;  3V8U A;  3UAQ A;  2J1N A;  4E1T A;  4G75 A;  3AAE A;  2Y7S A;  4O3Z A;  1ZHX A;  5G26 A;  2W80 C;  2LHF A;  4O4X A;  2FGQ X;  2XTR A;  2KXP B;  2KZ7 B;  3VY9 X;  2N2L A;  3WI5 A;  4KR8 A;  4AFK A;  4AKR A;  1ZHT A;  2M07 A;  4D5U A;  4O3X B;  5EE2 A;  4FOZ A;  4AUI A;  3RBH A;  5ADX L;  3LK3 B;  2YPV A;  3HWB A;  4FZN A;  1PHO A;  3VY8 X;  3HW9 A;  2ODJ A;  3POR A;  3T0S A;  2Y0L A;  4GCP A;  2N2M A;  2X27 X;  3UU2 A;  3SZV A;  2F1T A;  4U9C A;  5AFU K;  5DL8 A;  2FGR A;  4RLB A;  2QTK A;  4JFB A;  1PRN A;  3JTY A;  5FVN A;  4D65 A;  3VZW X;  2XMX A;  4GCS A;  4O49 A;  1P4T A;  1GFN A;  3POQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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