4GCPA

Crystal structure of e. coli ompf porin in complex with ampicillin
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
333
structure length
333
Chain Sequence
GNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Binding of Antibiotics in OmpF Porin.
pubmed doi rcsb
molecule tags Membrane protein/antibiotic
source organism Escherichia coli
molecule keywords Outer membrane protein F
total genus 99
structure length 333
sequence length 333
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00267 Porin_1 Gram-negative porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 4gcpA00
1H6S1 5JDPA 5PRNA 1HXTA 1BT9A 4FSOA 5DL7A 2J1NA 2ZLDA 3T24A 1PRNA 2Y0KA 4BUMX 4FOZA 2Y0LA 4GCQA 4GCSA 5DL8A 2QTKA 3SYSA 3T0SA 3K19A 3VY8X 4LSHA 3VZWX 4AUIA 1E54A 3SZVA 3HWBA 4KR4A 4RJXA 1HXUA 3UPGA 2ZFGA 1MPFA 2PORA 2XE2A 2K4TA 1GFNA 2Y0HA 4FT6A 1OSMA 3POQA 3NSGA 3SY9A 4D64A 4FMSA 2J4UP 1GFMA 8PRNA 1PHOA 4FSPA 5DL6A 3A2SX 3SZDA 4RJWA 3HW9A 3JTYA 1BH3A 2FGRA 5FVNA 3POXA 4FRXA 4JFBA 4FRTA 3T20A 2XE5A 3UU2A 3EMNX 1GFPA 2XE1A 2XE3A 4LSEA 2ODJA 1GFOA 4GCPA 3SY7A 3VY9X 3SYBA 3PRNA 3WI5A 2O4VA 4KR8A 4C69X 3WI4A 6PRNA 1HXXA 2Y2XA 7PRNA 3FYXA 4D65A 4LSFA 3POUA 2OMFA 2FGQX 1OPFA 2PRNA 4KRAA 5DL5A 4D5UA 1GFQA 3O0EA 3VZTX 2XG6A 3VZUX 4LSIA 3PORA
chains in the Genus database with same CATH superfamily
2XMXA 1H6S1 4JCHA 2F1VA 2F1CX 4FQEA 3QRCA 4UB6O 2XTRA 5PRNA 5JDPA 3TZGA 1ZHZA 1HXTA 5EE2A 1BT9A 4FSOA 5DL7A 2KXPB 3A0HO 5D5DA 3AA0B 3LK42 2J1NA 5KAIO 2JQYA 1ZHWA 3C5OA 2WJRA 2ZLDA 3KVDD 3T24A 4O3YA 1PRNA 2LHFA 2Y0KA 4FUVA 3VE2A 4C00A 4PUXA 1G90A 4BUMX 1ORMA 2R4PA 3LK3A 4FOZA 2Y0LA 4AYMC 4GCQA 4C4VB 4U9CA 3DWOX 4O4XA 4E1SA 4AKRB 3BS0A 4GCSA 5TISO 1IZNB 5DL8A 4IL6O 2AXTO 2LFUA 4O3XB 2QTKA 3SYSA 3T0SA 2F1TA 2Y7SA 3HOEA 4RLCA 5GV0A 3K19A 3VY8X 3V8UA 2KXPA 5E79O 1THQA 3AA0A 4LSHA 3BRYA 3VZWX 2R4OA 4AKMA 4AYEC 3PGRA 2X27X 3KZIO 3VE1A 2IWVA 2KZ7B 4QQ1A 4AUIA 1E54A 2M06A 4XNKA 3SZVA 3G7GA 3HWBA 4KR4A 4RJXA 4F4BA 4K3BA 4C4VA 1HXUA 4AYID 3AA6B 5H2FO 4K3CA 2ZFGA 3BRZA 1MPFA 4RLBA 3AA7B 4G76A 4AKRA 3UPGA 1IZNA 2PORA 4N75A 2MNHA 3AA1B 1MM4A 4FZLA 1YS5A 4G75A 4GHBA 2XE2A 2K4TA 4N59A 5G39A 1GFNA 3AAAB 2Y0HA 4FT6A 1OSMA 4GF4A 1BXWA 3LK2B 2KC0A 3NSGA 3POQA 3SY9A 4D64A 4FMSA 4RL9A 3RBHA 2J4UP 1GFMA 4FESA 4FZMA 5G3AA 5KAFO 4CTDA 4UB8O 4N74A 1PHOA 3DZMA 2KZ7A 4AYDC 8PRNA 4O3ZA 3HOLA 4FSPA 3A2SX 4N58A 1ZHTA 4RJWA 5DL6A 3SZDA 5GTHO 3HW9A 3UAQA 2N2LA 1ZHXA 3JTYA 2W80C 3AA6A 1Q9FA 3PGUA 1BH3A 2FGRA 3LK41 3AA7A 5FVNA 5GTIO 1T16A 3POXA 2WJQA 4FRXA 4JFBA 4FRTA 1P4TA 1MM5A 3AA1A 4AZLA 1Q9GA 3T20A 2XE5A 3PGSA 3UU2A 3EMNX 2ERVA 2K0LA 3JCUO 1QJ8A 3AAAA 4O4UA 3LK2A 1GFPA 2R4LA 2XE1A 2YPVA 3DA4A 4XNLA 2N2MA 2R88A 5G26A 2W81C 2XE3A 4LSEA 2ODJA 1GFOA 4GCPA 5G38A 2R89A 1ZHYA 3SY7A 3SYBA 3PRNA 3VY9X 3WI5A 2O4VA 2XTQA 4KR8A 2IWWA 4C69X 3PQUA 2GE4A 2M07A 1QJ9A 3WI4A 6PRNA 1HXXA 5T5FA 2Y2XA 3PQSA 3FYXA 7PRNA 3DA3A 4D65A 2KDYA 4LSFA 3POUA 5B66O 2R8AA 1S5LO 2OMFA 5ADXL 3DWNA 5ADXK 4Z3TA 4O49A 2FGQX 3QRAA 4AYNA 3GP6A 1OPFA 1QJPA 2PRNA 3WU2O 4KRAA 5DL5A 1T1LA 3AAEA 4D5UA 3A0BO 4FZNA 4PJ0O 1GFQA 5B5EO 3NJTA 4E1TA 3PF1A 3O0EA 2MHLA 3VZTX 4O3WA 4AFKA 2XG6A 3LK3B 2JMMA 3VZUX 3AAEB 2WVPA 5AFUL 5IYUA 5AFUK 2R4NA 2X9KA 4LSIA 4PR7A 4B61A 3PORA 2YNKA
chains in the Genus database with same CATH topology
2XMXA 1H6S1 4JCHA 2F1VA 3QRCA 2XTRA 5PRNA 5JDPA 3TZGA 1ZHZA 1HXTA 5EE2A 1BT9A 4FSOA 5DL7A 2KXPB 5D5DA 3AA0B 3LK42 2J1NA 1ZHWA 3C5OA 2ZLDA 3KVDD 3T24A 4O3YA 1PRNA 2LHFA 2Y0KA 4FUVA 3VE2A 1G90A 4PUXA 4BUMX 1ORMA 3LK3A 4FOZA 2Y0LA 4AYMC 4GCQA 4U9CA 4O4XA 4E1SA 4AKRB 4GCSA 1IZNB 5DL8A 4O3XB 2LFUA 2QTKA 3SYSA 3T0SA 2F1TA 2Y7SA 3HOEA 4RLCA 5GV0A 3K19A 3VY8X 3V8UA 2KXPA 1THQA 3AA0A 4LSHA 3VZWX 4AKMA 4AYEC 2X27X 3VE1A 2KZ7B 4QQ1A 4AUIA 1E54A 2M06A 4XNKA 3SZVA 3G7GA 3HWBA 4KR4A 4RJXA 4F4BA 1HXUA 4AYID 3AA6B 4RLBA 2ZFGA 3UPGA 1MPFA 4AKRA 3AA7B 4G76A 1IZNA 2PORA 2MNHA 3AA1B 1MM4A 4FZLA 1YS5A 4G75A 4GHBA 2XE2A 2K4TA 4N59A 1GFNA 3AAAB 2Y0HA 4FT6A 1OSMA 4GF4A 1BXWA 3LK2B 2KC0A 3NSGA 3POQA 3SY9A 4D64A 4FMSA 4RL9A 3RBHA 2J4UP 1GFMA 4FESA 4FZMA 8PRNA 1PHOA 2KZ7A 4AYDC 4O3ZA 3HOLA 4FSPA 3A2SX 4N58A 1ZHTA 4RJWA 5DL6A 3SZDA 3HW9A 3UAQA 2N2LA 1ZHXA 3JTYA 2W80C 3AA6A 1Q9FA 1BH3A 2FGRA 3LK41 3AA7A 5FVNA 3POXA 4FRXA 4JFBA 4FRTA 1P4TA 1MM5A 3AA1A 4AZLA 1Q9GA 3T20A 2XE5A 3UU2A 3EMNX 2ERVA 2K0LA 1QJ8A 3AAAA 4O4UA 3LK2A 1GFPA 2XE1A 3DA4A 2YPVA 4XNLA 5G26A 2N2MA 2W81C 2XE3A 4LSEA 2ODJA 1GFOA 4GCPA 1ZHYA 3SY7A 3SYBA 3PRNA 3VY9X 3WI5A 2O4VA 2XTQA 4KR8A 4C69X 3PQUA 2GE4A 2M07A 1QJ9A 3WI4A 6PRNA 1HXXA 5T5FA 2Y2XA 3PQSA 3FYXA 7PRNA 3DA3A 4D65A 2KDYA 4LSFA 3POUA 2OMFA 5ADXL 5ADXK 4Z3TA 4O49A 2FGQX 3QRAA 4AYNA 3GP6A 1OPFA 1QJPA 2PRNA 4KRAA 5DL5A 3AAEA 4D5UA 4FZNA 1GFQA 4E1TA 4AFKA 3O0EA 2MHLA 3VZTX 4O3WA 2XG6A 3LK3B 2JMMA 3VZUX 3AAEB 5AFUL 5IYUA 5AFUK 4LSIA 4B61A 3PORA 2YNKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1H6S 1;  5JDP A;  5PRN A;  1HXT A;  1BT9 A;  4FSO A;  5DL7 A;  2J1N A;  2ZLD A;  3T24 A;  1PRN A;  2Y0K A;  4BUM X;  4FOZ A;  2Y0L A;  4GCQ A;  4GCS A;  5DL8 A;  2QTK A;  3SYS A;  3T0S A;  3K19 A;  3VY8 X;  4LSH A;  3VZW X;  4AUI A;  1E54 A;  3SZV A;  3HWB A;  4KR4 A;  4RJX A;  1HXU A;  3UPG A;  2ZFG A;  1MPF A;  2POR A;  2XE2 A;  2K4T A;  1GFN A;  2Y0H A;  4FT6 A;  1OSM A;  3POQ A;  3NSG A;  3SY9 A;  4D64 A;  4FMS A;  2J4U P;  1GFM A;  8PRN A;  1PHO A;  4FSP A;  5DL6 A;  3A2S X;  3SZD A;  4RJW A;  3HW9 A;  3JTY A;  1BH3 A;  2FGR A;  5FVN A;  3POX A;  4FRX A;  4JFB A;  4FRT A;  3T20 A;  2XE5 A;  3UU2 A;  3EMN X;  1GFP A;  2XE1 A;  2XE3 A;  4LSE A;  2ODJ A;  1GFO A;  4GCP A;  3SY7 A;  3VY9 X;  3SYB A;  3PRN A;  3WI5 A;  2O4V A;  4KR8 A;  4C69 X;  3WI4 A;  6PRN A;  1HXX A;  2Y2X A;  7PRN A;  3FYX A;  4D65 A;  4LSF A;  3POU A;  2OMF A;  2FGQ X;  1OPF A;  2PRN A;  4KRA A;  5DL5 A;  4D5U A;  1GFQ A;  3O0E A;  3VZT X;  2XG6 A;  3VZU X;  4LSI A;  3POR A; 
#chains in the Genus database with same CATH topology
 2XMX A;  1H6S 1;  4JCH A;  2F1V A;  2F1C X;  4FQE A;  3QRC A;  4UB6 O;  2XTR A;  5PRN A;  5JDP A;  3TZG A;  1ZHZ A;  1HXT A;  5EE2 A;  1BT9 A;  4FSO A;  5DL7 A;  2KXP B;  3A0H O;  5D5D A;  3AA0 B;  3LK4 2;  2J1N A;  5KAI O;  2JQY A;  1ZHW A;  3C5O A;  2WJR A;  2ZLD A;  3KVD D;  3T24 A;  4O3Y A;  1PRN A;  2LHF A;  2Y0K A;  4FUV A;  3VE2 A;  4C00 A;  4PUX A;  1G90 A;  4BUM X;  1ORM A;  2R4P A;  3LK3 A;  4FOZ A;  2Y0L A;  4AYM C;  4GCQ A;  4C4V B;  4U9C A;  3DWO X;  4O4X A;  4E1S A;  4AKR B;  3BS0 A;  4GCS A;  5TIS O;  1IZN B;  5DL8 A;  4IL6 O;  2AXT O;  2LFU A;  4O3X B;  2QTK A;  3SYS A;  3T0S A;  2F1T A;  2Y7S A;  3HOE A;  4RLC A;  5GV0 A;  3K19 A;  3VY8 X;  3V8U A;  2KXP A;  5E79 O;  1THQ A;  3AA0 A;  4LSH A;  3BRY A;  3VZW X;  2R4O A;  4AKM A;  4AYE C;  3PGR A;  2X27 X;  3KZI O;  3VE1 A;  2IWV A;  2KZ7 B;  4QQ1 A;  4AUI A;  1E54 A;  2M06 A;  4XNK A;  3SZV A;  3G7G A;  3HWB A;  4KR4 A;  4RJX A;  4F4B A;  4K3B A;  4C4V A;  1HXU A;  4AYI D;  3AA6 B;  5H2F O;  4K3C A;  2ZFG A;  3BRZ A;  1MPF A;  4RLB A;  3AA7 B;  4G76 A;  4AKR A;  3UPG A;  1IZN A;  2POR A;  4N75 A;  2MNH A;  3AA1 B;  1MM4 A;  4FZL A;  1YS5 A;  4G75 A;  4GHB A;  2XE2 A;  2K4T A;  4N59 A;  5G39 A;  1GFN A;  3AAA B;  2Y0H A;  4FT6 A;  1OSM A;  4GF4 A;  1BXW A;  3LK2 B;  2KC0 A;  3NSG A;  3POQ A;  3SY9 A;  4D64 A;  4FMS A;  4RL9 A;  3RBH A;  2J4U P;  1GFM A;  4FES A;  4FZM A;  5G3A A;  5KAF O;  4CTD A;  4UB8 O;  4N74 A;  1PHO A;  3DZM A;  2KZ7 A;  4AYD C;  8PRN A;  4O3Z A;  3HOL A;  4FSP A;  3A2S X;  4N58 A;  1ZHT A;  4RJW A;  5DL6 A;  3SZD A;  5GTH O;  3HW9 A;  3UAQ A;  2N2L A;  1ZHX A;  3JTY A;  2W80 C;  3AA6 A;  1Q9F A;  3PGU A;  1BH3 A;  2FGR A;  3LK4 1;  3AA7 A;  5FVN A;  5GTI O;  1T16 A;  3POX A;  2WJQ A;  4FRX A;  4JFB A;  4FRT A;  1P4T A;  1MM5 A;  3AA1 A;  4AZL A;  1Q9G A;  3T20 A;  2XE5 A;  3PGS A;  3UU2 A;  3EMN X;  2ERV A;  2K0L A;  3JCU O;  1QJ8 A;  3AAA A;  4O4U A;  3LK2 A;  1GFP A;  2R4L A;  2XE1 A;  2YPV A;  3DA4 A;  4XNL A;  2N2M A;  2R88 A;  5G26 A;  2W81 C;  2XE3 A;  4LSE A;  2ODJ A;  1GFO A;  4GCP A;  5G38 A;  2R89 A;  1ZHY A;  3SY7 A;  3SYB A;  3PRN A;  3VY9 X;  3WI5 A;  2O4V A;  2XTQ A;  4KR8 A;  2IWW A;  4C69 X;  3PQU A;  2GE4 A;  2M07 A;  1QJ9 A;  3WI4 A;  6PRN A;  1HXX A;  5T5F A;  2Y2X A;  3PQS A;  3FYX A;  7PRN A;  3DA3 A;  4D65 A;  2KDY A;  4LSF A;  3POU A;  5B66 O;  2R8A A;  1S5L O;  2OMF A;  5ADX L;  3DWN A;  5ADX K;  4Z3T A;  4O49 A;  2FGQ X;  3QRA A;  4AYN A;  3GP6 A;  1OPF A;  1QJP A;  2PRN A;  3WU2 O;  4KRA A;  5DL5 A;  1T1L A;  3AAE A;  4D5U A;  3A0B O;  4FZN A;  4PJ0 O;  1GFQ A;  5B5E O;  3NJT A;  4E1T A;  3PF1 A;  3O0E A;  2MHL A;  3VZT X;  4O3W A;  4AFK A;  2XG6 A;  3LK3 B;  2JMM A;  3VZU X;  3AAE B;  2WVP A;  5AFU L;  5IYU A;  5AFU K;  2R4N A;  2X9K A;  4LSI A;  4PR7 A;  4B61 A;  3POR A;  2YNK A; 
#chains in the Genus database with same CATH homology
 2XMX A;  1H6S 1;  4JCH A;  2F1V A;  3QRC A;  2XTR A;  5PRN A;  5JDP A;  3TZG A;  1ZHZ A;  1HXT A;  5EE2 A;  1BT9 A;  4FSO A;  5DL7 A;  2KXP B;  5D5D A;  3AA0 B;  3LK4 2;  2J1N A;  1ZHW A;  3C5O A;  2ZLD A;  3KVD D;  3T24 A;  4O3Y A;  1PRN A;  2LHF A;  2Y0K A;  4FUV A;  3VE2 A;  1G90 A;  4PUX A;  4BUM X;  1ORM A;  3LK3 A;  4FOZ A;  2Y0L A;  4AYM C;  4GCQ A;  4U9C A;  4O4X A;  4E1S A;  4AKR B;  4GCS A;  1IZN B;  5DL8 A;  4O3X B;  2LFU A;  2QTK A;  3SYS A;  3T0S A;  2F1T A;  2Y7S A;  3HOE A;  4RLC A;  5GV0 A;  3K19 A;  3VY8 X;  3V8U A;  2KXP A;  1THQ A;  3AA0 A;  4LSH A;  3VZW X;  4AKM A;  4AYE C;  2X27 X;  3VE1 A;  2KZ7 B;  4QQ1 A;  4AUI A;  1E54 A;  2M06 A;  4XNK A;  3SZV A;  3G7G A;  3HWB A;  4KR4 A;  4RJX A;  4F4B A;  1HXU A;  4AYI D;  3AA6 B;  4RLB A;  2ZFG A;  3UPG A;  1MPF A;  4AKR A;  3AA7 B;  4G76 A;  1IZN A;  2POR A;  2MNH A;  3AA1 B;  1MM4 A;  4FZL A;  1YS5 A;  4G75 A;  4GHB A;  2XE2 A;  2K4T A;  4N59 A;  1GFN A;  3AAA B;  2Y0H A;  4FT6 A;  1OSM A;  4GF4 A;  1BXW A;  3LK2 B;  2KC0 A;  3NSG A;  3POQ A;  3SY9 A;  4D64 A;  4FMS A;  4RL9 A;  3RBH A;  2J4U P;  1GFM A;  4FES A;  4FZM A;  8PRN A;  1PHO A;  2KZ7 A;  4AYD C;  4O3Z A;  3HOL A;  4FSP A;  3A2S X;  4N58 A;  1ZHT A;  4RJW A;  5DL6 A;  3SZD A;  3HW9 A;  3UAQ A;  2N2L A;  1ZHX A;  3JTY A;  2W80 C;  3AA6 A;  1Q9F A;  1BH3 A;  2FGR A;  3LK4 1;  3AA7 A;  5FVN A;  3POX A;  4FRX A;  4JFB A;  4FRT A;  1P4T A;  1MM5 A;  3AA1 A;  4AZL A;  1Q9G A;  3T20 A;  2XE5 A;  3UU2 A;  3EMN X;  2ERV A;  2K0L A;  1QJ8 A;  3AAA A;  4O4U A;  3LK2 A;  1GFP A;  2XE1 A;  3DA4 A;  2YPV A;  4XNL A;  5G26 A;  2N2M A;  2W81 C;  2XE3 A;  4LSE A;  2ODJ A;  1GFO A;  4GCP A;  1ZHY A;  3SY7 A;  3SYB A;  3PRN A;  3VY9 X;  3WI5 A;  2O4V A;  2XTQ A;  4KR8 A;  4C69 X;  3PQU A;  2GE4 A;  2M07 A;  1QJ9 A;  3WI4 A;  6PRN A;  1HXX A;  5T5F A;  2Y2X A;  3PQS A;  3FYX A;  7PRN A;  3DA3 A;  4D65 A;  2KDY A;  4LSF A;  3POU A;  2OMF A;  5ADX L;  5ADX K;  4Z3T A;  4O49 A;  2FGQ X;  3QRA A;  4AYN A;  3GP6 A;  1OPF A;  1QJP A;  2PRN A;  4KRA A;  5DL5 A;  3AAE A;  4D5U A;  4FZN A;  1GFQ A;  4E1T A;  4AFK A;  3O0E A;  2MHL A;  3VZT X;  4O3W A;  2XG6 A;  3LK3 B;  2JMM A;  3VZU X;  3AAE B;  5AFU L;  5IYU A;  5AFU K;  4LSI A;  4B61 A;  3POR A;  2YNK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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