3EMNX

The crystal structure of mouse vdac1 at 2.3 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
283
structure length
283
Chain Sequence
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Membrane protein
molecule keywords Voltage-dependent anion-selective channel protein 1
publication title The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating
pubmed doi rcsb
source organism Mus musculus
total genus 63
structure length 283
sequence length 283
ec nomenclature
pdb deposition date 2008-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 3emnX00
6PRNA 1MPFA 4KR4A 5PRNA 7PRNA 4D65A 2Y0KA 4FMSA 3VZUX 3POXA 2XG6A 1E54A 3HWBA 4LSHA 3SYBA 3VZWX 1HXTA 2ODJA 5DL5A 1GFMA 2J4UP 1HXXA 4JFBA 2ZFGA 3POQA 3T0SA 2QTKA 3UU2A 1H6S1 1HXUA 5FVNA 3SYSA 4D64A 3POUA 2XE1A 3O0EA 1BT9A 1PHOA 4KRAA 1PRNA 1BH3A 2XE2A 1GFOA 2XE3A 4FSOA 2PORA 4LSIA 4GCQA 3WI5A 3SY9A 8PRNA 3T24A 2Y0LA 2Y2XA 4RJXA 4AUIA 2J1NA 3EMNX 1GFPA 2PRNA 3JTYA 3VZTX 2O4VA 4RJWA 4GCSA 2XE5A 3FYXA 3WI4A 1OSMA 4LSEA 5DL8A 5DL7A 3VY9X 3PRNA 4LSFA 3SZVA 2OMFA 3T20A 4FOZA 4FT6A 4KR8A 1GFQA 4C69X 3VY8X 3HW9A 2FGRA 4BUMX 3SY7A 3PORA 3K19A 3UPGA 4FSPA 4FRXA 3A2SX 2K4TA 2FGQX 1GFNA 2Y0HA 1OPFA 3NSGA 5JDPA 4GCPA 4D5UA 2ZLDA 5DL6A 3SZDA 4FRTA
chains in the Genus database with same CATH superfamily
6PRNA 4B61A 3GP6A 4IL6O 1MPFA 1MM4A 2WVPA 3AAAA 3DA4A 3DWOX 4KR4A 4FZNA 4AYDC 5PRNA 2R89A 5B66O 5G39A 7PRNA 3AA1B 4D65A 2Y0KA 4UB8O 4FMSA 2IWVA 3NJTA 4AKMA 3UAQA 3LK42 3POXA 3VZUX 2XG6A 3BRYA 3BS0A 5GV0A 5KAFO 2XTQA 4FZMA 1E54A 3HWBA 4K3CA 4LSHA 4XNLA 3SYBA 3A0HO 3AA1A 3SZDA 3VZWX 1HXTA 2GE4A 1QJPA 3DWNA 2ODJA 2KZ7B 3PGRA 4F4BA 3PF1A 2AXTO 3AA7A 3LK3A 5E79O 4C00A 5DL5A 4E1TA 1GFMA 3DZMA 2X9KA 4GF4A 3TZGA 2J4UP 2KXPA 4FESA 1HXXA 4AYMC 2W81C 4JFBA 2W80C 3AAAB 2LFUA 2ZFGA 3POQA 4JCHA 1S5LO 4FQEA 2QTKA 3T0SA 3UU2A 1H6S1 2K0LA 3HOLA 3V8UA 3AA6B 1HXUA 4AYEC 5ADXL 5FVNA 1T16A 3SYSA 4D64A 3RBHA 2KDYA 3POUA 2MNHA 2XE1A 3O0EA 1BT9A 1PHOA 4FZLA 3AA6A 3QRAA 4KRAA 1PRNA 1BH3A 1ZHTA 4PR7A 3LK41 3G7GA 5G38A 2XE2A 1GFOA 2XE3A 1P4TA 2XMXA 3AA7B 3DA3A 1ZHYA 2PORA 3LK3B 4K3BA 4N75A 2IWWA 4LSIA 2KXPB 2KC0A 4GCQA 3WI5A 4GHBA 4PUXA 2R4LA 4QQ1A 3SY9A 2XTRA 3LK2A 1QJ8A 8PRNA 5EE2A 4AFKA 3PGSA 4RLCA 4G75A 3T24A 5IYUA 4N58A 2F1VA 2Y0LA 3HOEA 3PQUA 4UB6O 4AYID 2N2MA 4C4VB 1T1LA 2Y2XA 4RJXA 4AKRA 1ZHWA 4AZLA 4Z3TA 4N59A 4AUIA 2R4OA 3KZIO 2J1NA 3EMNX 3VE2A 2JMMA 1GFPA 4O49A 5D5DA 5T5FA 4C4VA 1ORMA 2R8AA 3AA0A 3BRZA 4U9CA 2PRNA 4O3WA 4CTDA 1Q9FA 2R4PA 4O3ZA 3JTYA 2X27X 1ZHZA 2ERVA 2M07A 3LK2B 2O4VA 4G76A 4RJWA 4GCSA 3VZTX 1IZNA 2XE5A 3AAEB 4AYNA 3FYXA 2F1CX 3WI4A 1OSMA 4LSEA 4O3XB 4RL9A 5G3AA 1ZHXA 5DL8A 5DL7A 3VY9X 4AKRB 2LHFA 1QJ9A 3PRNA 4O4XA 3PQSA 4LSFA 2WJQA 3AAEA 4FSOA 5B5EO 4O3YA 3QRCA 3SZVA 5H2FO 2OMFA 1Q9GA 2M06A 2JQYA 5AFUL 3T20A 4FOZA 4FT6A 4KR8A 5GTIO 1MM5A 3AA0B 4O4UA 1GFQA 4C69X 3VY8X 3HW9A 5AFUK 5TISO 2FGRA 3JCUO 4BUMX 3SY7A 3PORA 2F1TA 2Y7SA 2YPVA 3K19A 4RLBA 1IZNB 3VE1A 3UPGA 3A0BO 4FUVA 2R88A 2R4NA 4FSPA 2MHLA 4FRXA 3A2SX 2K4TA 2FGQX 2YNKA 3C5OA 1YS5A 5ADXK 1THQA 1GFNA 4E1SA 2Y0HA 2N2LA 5GTHO 1OPFA 3NSGA 4PJ0O 5G26A 4GCPA 5JDPA 4D5UA 4XNKA 3WU2O 1G90A 2KZ7A 2ZLDA 4N74A 5DL6A 3PGUA 5KAIO 3KVDD 4FRTA 2WJRA 1BXWA
chains in the Genus database with same CATH topology
6PRNA 4B61A 3GP6A 1MPFA 1MM4A 3AAAA 3DA4A 4KR4A 4AYDC 5ADXK 4FZNA 5PRNA 7PRNA 3AA1B 4D65A 2Y0KA 4FMSA 4AKMA 3UAQA 3LK42 3POXA 3VZUX 2XG6A 5GV0A 2XTQA 4FZMA 1E54A 3HWBA 4LSHA 4XNLA 3SYBA 3AA1A 3SZDA 3VZWX 1HXTA 2GE4A 1QJPA 2ODJA 2KZ7B 4F4BA 3AA7A 3LK3A 4E1TA 5DL5A 1GFMA 3TZGA 4GF4A 2J4UP 2KXPA 4FESA 1HXXA 4AYMC 2W81C 4JFBA 2W80C 3AAAB 2LFUA 2ZFGA 3POQA 4JCHA 3T0SA 2QTKA 3UU2A 4AYEC 1H6S1 2K0LA 3HOLA 3V8UA 3AA6B 1HXUA 5ADXL 5FVNA 3SYSA 4D64A 3RBHA 2KDYA 3POUA 2MNHA 2XE1A 3O0EA 1BT9A 1PHOA 4FZLA 3AA6A 3QRAA 4KRAA 1PRNA 1BH3A 1ZHTA 3LK41 3G7GA 2XE2A 1GFOA 2XE3A 1P4TA 2XMXA 3AA7B 3DA3A 1ZHYA 2PORA 3LK3B 4LSIA 2KXPB 2KC0A 4GCQA 3WI5A 4GHBA 4PUXA 4QQ1A 3SY9A 2XTRA 3LK2A 1QJ8A 8PRNA 5EE2A 4AFKA 4RLCA 3T24A 4G75A 5IYUA 4N58A 2F1VA 2Y0LA 3HOEA 3PQUA 4AYID 2N2MA 4Z3TA 2Y2XA 4RJXA 4AKRA 1ZHWA 4AZLA 4N59A 4AUIA 2J1NA 3EMNX 3VE2A 2JMMA 1GFPA 4O49A 5D5DA 5T5FA 1ORMA 3AA0A 4U9CA 2PRNA 4O3WA 1Q9FA 4O3ZA 3JTYA 2X27X 1ZHZA 2ERVA 2M07A 3LK2B 2O4VA 4G76A 4RJWA 4GCSA 3VZTX 1IZNA 2XE5A 3AAEB 4AYNA 3FYXA 3WI4A 1OSMA 4LSEA 4O3XB 4RL9A 1ZHXA 5DL8A 5DL7A 3VY9X 4AKRB 2LHFA 1QJ9A 3PRNA 4O4XA 3PQSA 4LSFA 3AAEA 4FSOA 4O3YA 3QRCA 3SZVA 2OMFA 1Q9GA 2M06A 5AFUL 3T20A 4FOZA 4FT6A 4KR8A 1MM5A 3AA0B 4O4UA 1GFQA 4C69X 3VY8X 3HW9A 5AFUK 2FGRA 4BUMX 3SY7A 3PORA 2F1TA 2Y7SA 2YPVA 3K19A 4RLBA 1IZNB 3VE1A 3UPGA 4FUVA 4FSPA 2MHLA 4FRXA 3A2SX 2K4TA 2FGQX 2YNKA 3C5OA 1YS5A 1THQA 1GFNA 4E1SA 2Y0HA 2N2LA 1OPFA 3NSGA 5G26A 5JDPA 4GCPA 4D5UA 4XNKA 1G90A 2KZ7A 2ZLDA 5DL6A 3KVDD 4FRTA 1BXWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 6PRN A;  1MPF A;  4KR4 A;  5PRN A;  7PRN A;  4D65 A;  2Y0K A;  4FMS A;  3VZU X;  3POX A;  2XG6 A;  1E54 A;  3HWB A;  4LSH A;  3SYB A;  3VZW X;  1HXT A;  2ODJ A;  5DL5 A;  1GFM A;  2J4U P;  1HXX A;  4JFB A;  2ZFG A;  3POQ A;  3T0S A;  2QTK A;  3UU2 A;  1H6S 1;  1HXU A;  5FVN A;  3SYS A;  4D64 A;  3POU A;  2XE1 A;  3O0E A;  1BT9 A;  1PHO A;  4KRA A;  1PRN A;  1BH3 A;  2XE2 A;  1GFO A;  2XE3 A;  4FSO A;  2POR A;  4LSI A;  4GCQ A;  3WI5 A;  3SY9 A;  8PRN A;  3T24 A;  2Y0L A;  2Y2X A;  4RJX A;  4AUI A;  2J1N A;  3EMN X;  1GFP A;  2PRN A;  3JTY A;  3VZT X;  2O4V A;  4RJW A;  4GCS A;  2XE5 A;  3FYX A;  3WI4 A;  1OSM A;  4LSE A;  5DL8 A;  5DL7 A;  3VY9 X;  3PRN A;  4LSF A;  3SZV A;  2OMF A;  3T20 A;  4FOZ A;  4FT6 A;  4KR8 A;  1GFQ A;  4C69 X;  3VY8 X;  3HW9 A;  2FGR A;  4BUM X;  3SY7 A;  3POR A;  3K19 A;  3UPG A;  4FSP A;  4FRX A;  3A2S X;  2K4T A;  2FGQ X;  1GFN A;  2Y0H A;  1OPF A;  3NSG A;  5JDP A;  4GCP A;  4D5U A;  2ZLD A;  5DL6 A;  3SZD A;  4FRT A; 
#chains in the Genus database with same CATH topology
 6PRN A;  4B61 A;  3GP6 A;  4IL6 O;  1MPF A;  1MM4 A;  2WVP A;  3AAA A;  3DA4 A;  3DWO X;  4KR4 A;  4FZN A;  4AYD C;  5PRN A;  2R89 A;  5B66 O;  5G39 A;  7PRN A;  3AA1 B;  4D65 A;  2Y0K A;  4UB8 O;  4FMS A;  2IWV A;  3NJT A;  4AKM A;  3UAQ A;  3LK4 2;  3POX A;  3VZU X;  2XG6 A;  3BRY A;  3BS0 A;  5GV0 A;  5KAF O;  2XTQ A;  4FZM A;  1E54 A;  3HWB A;  4K3C A;  4LSH A;  4XNL A;  3SYB A;  3A0H O;  3AA1 A;  3SZD A;  3VZW X;  1HXT A;  2GE4 A;  1QJP A;  3DWN A;  2ODJ A;  2KZ7 B;  3PGR A;  4F4B A;  3PF1 A;  2AXT O;  3AA7 A;  3LK3 A;  5E79 O;  4C00 A;  5DL5 A;  4E1T A;  1GFM A;  3DZM A;  2X9K A;  4GF4 A;  3TZG A;  2J4U P;  2KXP A;  4FES A;  1HXX A;  4AYM C;  2W81 C;  4JFB A;  2W80 C;  3AAA B;  2LFU A;  2ZFG A;  3POQ A;  4JCH A;  1S5L O;  4FQE A;  2QTK A;  3T0S A;  3UU2 A;  1H6S 1;  2K0L A;  3HOL A;  3V8U A;  3AA6 B;  1HXU A;  4AYE C;  5ADX L;  5FVN A;  1T16 A;  3SYS A;  4D64 A;  3RBH A;  2KDY A;  3POU A;  2MNH A;  2XE1 A;  3O0E A;  1BT9 A;  1PHO A;  4FZL A;  3AA6 A;  3QRA A;  4KRA A;  1PRN A;  1BH3 A;  1ZHT A;  4PR7 A;  3LK4 1;  3G7G A;  5G38 A;  2XE2 A;  1GFO A;  2XE3 A;  1P4T A;  2XMX A;  3AA7 B;  3DA3 A;  1ZHY A;  2POR A;  3LK3 B;  4K3B A;  4N75 A;  2IWW A;  4LSI A;  2KXP B;  2KC0 A;  4GCQ A;  3WI5 A;  4GHB A;  4PUX A;  2R4L A;  4QQ1 A;  3SY9 A;  2XTR A;  3LK2 A;  1QJ8 A;  8PRN A;  5EE2 A;  4AFK A;  3PGS A;  4RLC A;  4G75 A;  3T24 A;  5IYU A;  4N58 A;  2F1V A;  2Y0L A;  3HOE A;  3PQU A;  4UB6 O;  4AYI D;  2N2M A;  4C4V B;  1T1L A;  2Y2X A;  4RJX A;  4AKR A;  1ZHW A;  4AZL A;  4Z3T A;  4N59 A;  4AUI A;  2R4O A;  3KZI O;  2J1N A;  3EMN X;  3VE2 A;  2JMM A;  1GFP A;  4O49 A;  5D5D A;  5T5F A;  4C4V A;  1ORM A;  2R8A A;  3AA0 A;  3BRZ A;  4U9C A;  2PRN A;  4O3W A;  4CTD A;  1Q9F A;  2R4P A;  4O3Z A;  3JTY A;  2X27 X;  1ZHZ A;  2ERV A;  2M07 A;  3LK2 B;  2O4V A;  4G76 A;  4RJW A;  4GCS A;  3VZT X;  1IZN A;  2XE5 A;  3AAE B;  4AYN A;  3FYX A;  2F1C X;  3WI4 A;  1OSM A;  4LSE A;  4O3X B;  4RL9 A;  5G3A A;  1ZHX A;  5DL8 A;  5DL7 A;  3VY9 X;  4AKR B;  2LHF A;  1QJ9 A;  3PRN A;  4O4X A;  3PQS A;  4LSF A;  2WJQ A;  3AAE A;  4FSO A;  5B5E O;  4O3Y A;  3QRC A;  3SZV A;  5H2F O;  2OMF A;  1Q9G A;  2M06 A;  2JQY A;  5AFU L;  3T20 A;  4FOZ A;  4FT6 A;  4KR8 A;  5GTI O;  1MM5 A;  3AA0 B;  4O4U A;  1GFQ A;  4C69 X;  3VY8 X;  3HW9 A;  5AFU K;  5TIS O;  2FGR A;  3JCU O;  4BUM X;  3SY7 A;  3POR A;  2F1T A;  2Y7S A;  2YPV A;  3K19 A;  4RLB A;  1IZN B;  3VE1 A;  3UPG A;  3A0B O;  4FUV A;  2R88 A;  2R4N A;  4FSP A;  2MHL A;  4FRX A;  3A2S X;  2K4T A;  2FGQ X;  2YNK A;  3C5O A;  1YS5 A;  5ADX K;  1THQ A;  1GFN A;  4E1S A;  2Y0H A;  2N2L A;  5GTH O;  1OPF A;  3NSG A;  4PJ0 O;  5G26 A;  4GCP A;  5JDP A;  4D5U A;  4XNK A;  3WU2 O;  1G90 A;  2KZ7 A;  2ZLD A;  4N74 A;  5DL6 A;  3PGU A;  5KAI O;  3KVD D;  4FRT A;  2WJR A;  1BXW A; 
#chains in the Genus database with same CATH homology
 6PRN A;  4B61 A;  3GP6 A;  1MPF A;  1MM4 A;  3AAA A;  3DA4 A;  4KR4 A;  4AYD C;  5ADX K;  4FZN A;  5PRN A;  7PRN A;  3AA1 B;  4D65 A;  2Y0K A;  4FMS A;  4AKM A;  3UAQ A;  3LK4 2;  3POX A;  3VZU X;  2XG6 A;  5GV0 A;  2XTQ A;  4FZM A;  1E54 A;  3HWB A;  4LSH A;  4XNL A;  3SYB A;  3AA1 A;  3SZD A;  3VZW X;  1HXT A;  2GE4 A;  1QJP A;  2ODJ A;  2KZ7 B;  4F4B A;  3AA7 A;  3LK3 A;  4E1T A;  5DL5 A;  1GFM A;  3TZG A;  4GF4 A;  2J4U P;  2KXP A;  4FES A;  1HXX A;  4AYM C;  2W81 C;  4JFB A;  2W80 C;  3AAA B;  2LFU A;  2ZFG A;  3POQ A;  4JCH A;  3T0S A;  2QTK A;  3UU2 A;  4AYE C;  1H6S 1;  2K0L A;  3HOL A;  3V8U A;  3AA6 B;  1HXU A;  5ADX L;  5FVN A;  3SYS A;  4D64 A;  3RBH A;  2KDY A;  3POU A;  2MNH A;  2XE1 A;  3O0E A;  1BT9 A;  1PHO A;  4FZL A;  3AA6 A;  3QRA A;  4KRA A;  1PRN A;  1BH3 A;  1ZHT A;  3LK4 1;  3G7G A;  2XE2 A;  1GFO A;  2XE3 A;  1P4T A;  2XMX A;  3AA7 B;  3DA3 A;  1ZHY A;  2POR A;  3LK3 B;  4LSI A;  2KXP B;  2KC0 A;  4GCQ A;  3WI5 A;  4GHB A;  4PUX A;  4QQ1 A;  3SY9 A;  2XTR A;  3LK2 A;  1QJ8 A;  8PRN A;  5EE2 A;  4AFK A;  4RLC A;  3T24 A;  4G75 A;  5IYU A;  4N58 A;  2F1V A;  2Y0L A;  3HOE A;  3PQU A;  4AYI D;  2N2M A;  4Z3T A;  2Y2X A;  4RJX A;  4AKR A;  1ZHW A;  4AZL A;  4N59 A;  4AUI A;  2J1N A;  3EMN X;  3VE2 A;  2JMM A;  1GFP A;  4O49 A;  5D5D A;  5T5F A;  1ORM A;  3AA0 A;  4U9C A;  2PRN A;  4O3W A;  1Q9F A;  4O3Z A;  3JTY A;  2X27 X;  1ZHZ A;  2ERV A;  2M07 A;  3LK2 B;  2O4V A;  4G76 A;  4RJW A;  4GCS A;  3VZT X;  1IZN A;  2XE5 A;  3AAE B;  4AYN A;  3FYX A;  3WI4 A;  1OSM A;  4LSE A;  4O3X B;  4RL9 A;  1ZHX A;  5DL8 A;  5DL7 A;  3VY9 X;  4AKR B;  2LHF A;  1QJ9 A;  3PRN A;  4O4X A;  3PQS A;  4LSF A;  3AAE A;  4FSO A;  4O3Y A;  3QRC A;  3SZV A;  2OMF A;  1Q9G A;  2M06 A;  5AFU L;  3T20 A;  4FOZ A;  4FT6 A;  4KR8 A;  1MM5 A;  3AA0 B;  4O4U A;  1GFQ A;  4C69 X;  3VY8 X;  3HW9 A;  5AFU K;  2FGR A;  4BUM X;  3SY7 A;  3POR A;  2F1T A;  2Y7S A;  2YPV A;  3K19 A;  4RLB A;  1IZN B;  3VE1 A;  3UPG A;  4FUV A;  4FSP A;  2MHL A;  4FRX A;  3A2S X;  2K4T A;  2FGQ X;  2YNK A;  3C5O A;  1YS5 A;  1THQ A;  1GFN A;  4E1S A;  2Y0H A;  2N2L A;  1OPF A;  3NSG A;  5G26 A;  5JDP A;  4GCP A;  4D5U A;  4XNK A;  1G90 A;  2KZ7 A;  2ZLD A;  5DL6 A;  3KVD D;  4FRT A;  1BXW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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