3EMNX

The crystal structure of mouse vdac1 at 2.3 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
283
structure length
283
Chain Sequence
b'MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Voltage-dependent anion-selective channel protein 1
publication title The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating
pubmed doi rcsb
source organism Mus musculus
molecule tags Membrane protein
total genus 63
structure length 283
sequence length 283
ec nomenclature
pdb deposition date 2008-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 3emnX00
2PRNA 5JDPA 3POXA 3UPGA 3VZWX 3FYXA 1BH3A 2Y2XA 4FT6A 4KR4A 1GFNA 8PRNA 3VY8X 2Y0LA 7PRNA 4BUMX 1GFMA 3EMNX 4LSEA 2XE3A 3PRNA 3POUA 3POQA 1PRNA 1PHOA 2J1NA 2XG6A 3JTYA 5DL5A 4GCPA 3HWBA 3SY9A 1GFQA 2OMFA 3NSGA 6PRNA 4FMSA 1E54A 3UU2A 1HXTA 4LSFA 2ZFGA 1BT9A 3VZUX 3WI4A 2QTKA 1OPFA 3SZDA 2J4UP 3O0EA 4AUIA 1MPFA 5DL7A 2FGQX 4GCQA 1H6S1 2ZLDA 2O4VA 1OSMA 3VY9X 4RJXA 3SYSA 4FOZA 2XE1A 2XE2A 2FGRA 3T0SA 1GFOA 3SZVA 2XE5A 3SYBA 4LSIA 4KRAA 2Y0HA 1HXUA 2Y0KA 4KR8A 3T24A 4JFBA 3HW9A 3T20A 3SY7A 3WI5A 3VZTX 2K4TA 2PORA 4FSOA 5DL6A 5FVNA 4FRXA 5DL8A 4D64A 4FSPA 1HXXA 4D65A 4D5UA 4C69X 3K19A 4LSHA 3PORA 4RJWA 1GFPA 3A2SX 5PRNA 4FRTA 2ODJA 4GCSA
chains in the Genus database with same CATH superfamily
5B66O 2PRNA 3AA1B 5JDPA 5EE2A 2M07A 3POXA 2R4OA 4AYEC 2M06A 2F1CX 3VZWX 3UPGA 3PGSA 3FYXA 1BH3A 1S5LO 2Y2XA 3BRYA 5AFUK 4O49A 4FT6A 4XNLA 3V8UA 4KR4A 2IWWA 2R8AA 4O3XB 4AKRB 4O3YA 1GFNA 4O3ZA 3AA6A 3AA7B 4FESA 1IZNB 3DA4A 4U9CA 4C00A 4CTDA 8PRNA 4N74A 4AFKA 3VY8X 2Y0LA 3AAAA 3BRZA 3DWNA 5KAFO 3PGUA 7PRNA 3NJTA 1ZHXA 1BXWA 4N58A 4BUMX 2XTRA 5GTHO 4RL9A 3DZMA 2XTQA 1GFMA 3KZIO 4PR7A 5G38A 2R4PA 2F1VA 4FZLA 1THQA 3EMNX 2LFUA 2XE3A 4FUVA 4LSEA 3PRNA 3A0BO 5T5FA 5G26A 3JCUO 3POUA 3POQA 3LK2A 5D5DA 4FQEA 2WJQA 1PRNA 3AAAB 4F4BA 1PHOA 3AA7A 2J1NA 4GHBA 2XG6A 3JTYA 5GV0A 5DL5A 4G76A 2IWVA 4GCPA 2K0LA 4IL6O 4C4VA 5KAIO 2KDYA 3HWBA 4AKMA 2R89A 4N75A 2KC0A 2GE4A 3LK2B 2N2MA 4AYDC 5TISO 3SY9A 1GFQA 2OMFA 4AYID 3NSGA 1ZHZA 6PRNA 4FMSA 1E54A 2X9KA 1T1LA 3UU2A 4GF4A 4C4VB 4PUXA 4K3BA 1P4TA 1HXTA 4AYNA 3GP6A 2ZFGA 4LSFA 4RLCA 4PJ0O 5E79O 1BT9A 3PQSA 3VZUX 3WI4A 2AXTO 2QTKA 2R4NA 2R4LA 2X27X 3AAEA 2R88A 1OPFA 3VE1A 3SZDA 3QRCA 4AYMC 2N2LA 2J4UP 2JMMA 3C5OA 3O0EA 4AUIA 1MPFA 3A0HO 2ERVA 2FGQX 5DL7A 2KZ7B 5ADXL 5IYUA 4GCQA 2MNHA 1H6S1 3LK3A 2ZLDA 1G90A 2F1TA 2O4VA 3AAEB 5G3AA 1OSMA 4E1SA 3VY9X 4RJXA 3SYSA 4FOZA 2XE1A 2XE2A 4FZMA 1ORMA 2FGRA 3G7GA 3T0SA 4QQ1A 1GFOA 3SZVA 4N59A 1Q9GA 3AA0A 1QJ9A 1Q9FA 3LK3B 5H2FO 2XE5A 2YNKA 2KXPB 5GTIO 2KZ7A 4UB6O 2MHLA 3PQUA 5G39A 3SYBA 4JCHA 4Z3TA 4O3WA 4G75A 4LSIA 3QRAA 2XMXA 4KRAA 2Y0HA 3VE2A 1HXUA 3LK41 4O4XA 2Y0KA 4UB8O 1ZHYA 1T16A 4XNKA 3WU2O 5ADXK 2JQYA 3PF1A 4KR8A 5B5EO 3T24A 4JFBA 1QJ8A 3HW9A 3T20A 2YPVA 3AA0B 2WVPA 3SY7A 3WI5A 3RBHA 3TZGA 3VZTX 1ZHWA 4RLBA 4E1TA 2K4TA 2LHFA 2PORA 4FSOA 5DL6A 2KXPA 3HOLA 1YS5A 5FVNA 4FRXA 3BS0A 3DWOX 3DA3A 2Y7SA 4O4UA 5DL8A 4B61A 4K3CA 5AFUL 3UAQA 4FZNA 4D64A 3KVDD 4AZLA 1ZHTA 4FSPA 3AA1A 1HXXA 1MM5A 4D65A 2W81C 4D5UA 3PGRA 3K19A 4LSHA 3HOEA 3PORA 4C69X 1QJPA 4RJWA 3AA6B 2WJRA 1GFPA 3A2SX 4AKRA 5PRNA 4FRTA 2W80C 1IZNA 1MM4A 2ODJA 3LK42 4GCSA
chains in the Genus database with same CATH topology
2PRNA 3AA1B 5JDPA 5EE2A 2M07A 3POXA 4AYEC 3UPGA 2M06A 3VZWX 3FYXA 1BH3A 2Y2XA 5AFUK 4O49A 4FT6A 4XNLA 3V8UA 4KR4A 4O3XB 4AKRB 4O3YA 1GFNA 4O3ZA 3AA6A 3AA7B 4FESA 1IZNB 3DA4A 4U9CA 8PRNA 4AFKA 3VY8X 2Y0LA 3AAAA 7PRNA 1ZHXA 1BXWA 4N58A 4BUMX 2XTRA 4RL9A 2XTQA 1GFMA 2F1VA 4FZLA 1THQA 3EMNX 2LFUA 2XE3A 4FUVA 4LSEA 3PRNA 5T5FA 5G26A 3POUA 3POQA 3LK2A 5D5DA 1PRNA 3AAAB 4F4BA 1PHOA 3AA7A 2J1NA 4GHBA 2XG6A 3JTYA 5GV0A 5DL5A 4G76A 4GCPA 2K0LA 2KDYA 3HWBA 4AKMA 2KC0A 2GE4A 3LK2B 2N2MA 4AYDC 3SY9A 1GFQA 2OMFA 4AYID 3NSGA 1ZHZA 6PRNA 4FMSA 1E54A 3UU2A 4GF4A 4PUXA 1P4TA 1HXTA 4AYNA 3GP6A 2ZFGA 4LSFA 4RLCA 1BT9A 3PQSA 3VZUX 3WI4A 3AAEA 2QTKA 2X27X 1OPFA 3VE1A 3SZDA 3QRCA 4AYMC 2N2LA 2J4UP 2JMMA 3C5OA 3O0EA 4AUIA 1MPFA 2ERVA 2FGQX 5DL7A 2KZ7B 5ADXL 5IYUA 4GCQA 2MNHA 1H6S1 3LK3A 2ZLDA 1G90A 2F1TA 2O4VA 3AAEB 4E1SA 1OSMA 3VY9X 4RJXA 3SYSA 4FOZA 2XE1A 2XE2A 4FZMA 1ORMA 2FGRA 3G7GA 3T0SA 4QQ1A 1GFOA 3SZVA 4N59A 1Q9GA 3AA0A 1QJ9A 1Q9FA 3LK3B 2XE5A 2YNKA 2KXPB 2KZ7A 3SYBA 2MHLA 3PQUA 4JCHA 4Z3TA 4O3WA 4G75A 4LSIA 3QRAA 2XMXA 4KRAA 2Y0HA 3VE2A 1HXUA 3LK41 4O4XA 2Y0KA 4XNKA 1ZHYA 5ADXK 4KR8A 3T24A 4JFBA 1QJ8A 3HW9A 3T20A 2YPVA 3AA0B 3SY7A 3WI5A 3RBHA 3TZGA 3VZTX 1ZHWA 4RLBA 4E1TA 2K4TA 2LHFA 2PORA 4FSOA 5DL6A 2KXPA 3HOLA 1YS5A 5FVNA 4FRXA 4O4UA 3DA3A 2Y7SA 5AFUL 5DL8A 4B61A 3UAQA 4FZNA 4D64A 3KVDD 4AZLA 1ZHTA 4FSPA 3AA1A 1HXXA 1MM5A 4D65A 2W81C 4D5UA 4C69X 3K19A 4LSHA 3HOEA 3PORA 1QJPA 4RJWA 3AA6B 1GFPA 3A2SX 4AKRA 5PRNA 4FRTA 2W80C 1IZNA 1MM4A 2ODJA 3LK42 4GCSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PRN A;  5JDP A;  3POX A;  3UPG A;  3VZW X;  3FYX A;  1BH3 A;  2Y2X A;  4FT6 A;  4KR4 A;  1GFN A;  8PRN A;  3VY8 X;  2Y0L A;  7PRN A;  4BUM X;  1GFM A;  3EMN X;  4LSE A;  2XE3 A;  3PRN A;  3POU A;  3POQ A;  1PRN A;  1PHO A;  2J1N A;  2XG6 A;  3JTY A;  5DL5 A;  4GCP A;  3HWB A;  3SY9 A;  1GFQ A;  2OMF A;  3NSG A;  6PRN A;  4FMS A;  1E54 A;  3UU2 A;  1HXT A;  4LSF A;  2ZFG A;  1BT9 A;  3VZU X;  3WI4 A;  2QTK A;  1OPF A;  3SZD A;  2J4U P;  3O0E A;  4AUI A;  1MPF A;  5DL7 A;  2FGQ X;  4GCQ A;  1H6S 1;  2ZLD A;  2O4V A;  1OSM A;  3VY9 X;  4RJX A;  3SYS A;  4FOZ A;  2XE1 A;  2XE2 A;  2FGR A;  3T0S A;  1GFO A;  3SZV A;  2XE5 A;  3SYB A;  4LSI A;  4KRA A;  2Y0H A;  1HXU A;  2Y0K A;  4KR8 A;  3T24 A;  4JFB A;  3HW9 A;  3T20 A;  3SY7 A;  3WI5 A;  3VZT X;  2K4T A;  2POR A;  4FSO A;  5DL6 A;  5FVN A;  4FRX A;  5DL8 A;  4D64 A;  4FSP A;  1HXX A;  4D65 A;  4D5U A;  4C69 X;  3K19 A;  4LSH A;  3POR A;  4RJW A;  1GFP A;  3A2S X;  5PRN A;  4FRT A;  2ODJ A;  4GCS A; 
#chains in the Genus database with same CATH topology
 5B66 O;  2PRN A;  3AA1 B;  5JDP A;  5EE2 A;  2M07 A;  3POX A;  2R4O A;  4AYE C;  2M06 A;  2F1C X;  3VZW X;  3UPG A;  3PGS A;  3FYX A;  1BH3 A;  1S5L O;  2Y2X A;  3BRY A;  5AFU K;  4O49 A;  4FT6 A;  4XNL A;  3V8U A;  4KR4 A;  2IWW A;  2R8A A;  4O3X B;  4AKR B;  4O3Y A;  1GFN A;  4O3Z A;  3AA6 A;  3AA7 B;  4FES A;  1IZN B;  3DA4 A;  4U9C A;  4C00 A;  4CTD A;  8PRN A;  4N74 A;  4AFK A;  3VY8 X;  2Y0L A;  3AAA A;  3BRZ A;  3DWN A;  5KAF O;  3PGU A;  7PRN A;  3NJT A;  1ZHX A;  1BXW A;  4N58 A;  4BUM X;  2XTR A;  5GTH O;  4RL9 A;  3DZM A;  2XTQ A;  1GFM A;  3KZI O;  4PR7 A;  5G38 A;  2R4P A;  2F1V A;  4FZL A;  1THQ A;  3EMN X;  2LFU A;  2XE3 A;  4FUV A;  4LSE A;  3PRN A;  3A0B O;  5T5F A;  5G26 A;  3JCU O;  3POU A;  3POQ A;  3LK2 A;  5D5D A;  4FQE A;  2WJQ A;  1PRN A;  3AAA B;  4F4B A;  1PHO A;  3AA7 A;  2J1N A;  4GHB A;  2XG6 A;  3JTY A;  5GV0 A;  5DL5 A;  4G76 A;  2IWV A;  4GCP A;  2K0L A;  4IL6 O;  4C4V A;  5KAI O;  2KDY A;  3HWB A;  4AKM A;  2R89 A;  4N75 A;  2KC0 A;  2GE4 A;  3LK2 B;  2N2M A;  4AYD C;  5TIS O;  3SY9 A;  1GFQ A;  2OMF A;  4AYI D;  3NSG A;  1ZHZ A;  6PRN A;  4FMS A;  1E54 A;  2X9K A;  1T1L A;  3UU2 A;  4GF4 A;  4C4V B;  4PUX A;  4K3B A;  1P4T A;  1HXT A;  4AYN A;  3GP6 A;  2ZFG A;  4LSF A;  4RLC A;  4PJ0 O;  5E79 O;  1BT9 A;  3PQS A;  3VZU X;  3WI4 A;  2AXT O;  2QTK A;  2R4N A;  2R4L A;  2X27 X;  3AAE A;  2R88 A;  1OPF A;  3VE1 A;  3SZD A;  3QRC A;  4AYM C;  2N2L A;  2J4U P;  2JMM A;  3C5O A;  3O0E A;  4AUI A;  1MPF A;  3A0H O;  2ERV A;  2FGQ X;  5DL7 A;  2KZ7 B;  5ADX L;  5IYU A;  4GCQ A;  2MNH A;  1H6S 1;  3LK3 A;  2ZLD A;  1G90 A;  2F1T A;  2O4V A;  3AAE B;  5G3A A;  1OSM A;  4E1S A;  3VY9 X;  4RJX A;  3SYS A;  4FOZ A;  2XE1 A;  2XE2 A;  4FZM A;  1ORM A;  2FGR A;  3G7G A;  3T0S A;  4QQ1 A;  1GFO A;  3SZV A;  4N59 A;  1Q9G A;  3AA0 A;  1QJ9 A;  1Q9F A;  3LK3 B;  5H2F O;  2XE5 A;  2YNK A;  2KXP B;  5GTI O;  2KZ7 A;  4UB6 O;  2MHL A;  3PQU A;  5G39 A;  3SYB A;  4JCH A;  4Z3T A;  4O3W A;  4G75 A;  4LSI A;  3QRA A;  2XMX A;  4KRA A;  2Y0H A;  3VE2 A;  1HXU A;  3LK4 1;  4O4X A;  2Y0K A;  4UB8 O;  1ZHY A;  1T16 A;  4XNK A;  3WU2 O;  5ADX K;  2JQY A;  3PF1 A;  4KR8 A;  5B5E O;  3T24 A;  4JFB A;  1QJ8 A;  3HW9 A;  3T20 A;  2YPV A;  3AA0 B;  2WVP A;  3SY7 A;  3WI5 A;  3RBH A;  3TZG A;  3VZT X;  1ZHW A;  4RLB A;  4E1T A;  2K4T A;  2LHF A;  2POR A;  4FSO A;  5DL6 A;  2KXP A;  3HOL A;  1YS5 A;  5FVN A;  4FRX A;  3BS0 A;  3DWO X;  3DA3 A;  2Y7S A;  4O4U A;  5DL8 A;  4B61 A;  4K3C A;  5AFU L;  3UAQ A;  4FZN A;  4D64 A;  3KVD D;  4AZL A;  1ZHT A;  4FSP A;  3AA1 A;  1HXX A;  1MM5 A;  4D65 A;  2W81 C;  4D5U A;  3PGR A;  3K19 A;  4LSH A;  3HOE A;  3POR A;  4C69 X;  1QJP A;  4RJW A;  3AA6 B;  2WJR A;  1GFP A;  3A2S X;  4AKR A;  5PRN A;  4FRT A;  2W80 C;  1IZN A;  1MM4 A;  2ODJ A;  3LK4 2;  4GCS A; 
#chains in the Genus database with same CATH homology
 2PRN A;  3AA1 B;  5JDP A;  5EE2 A;  2M07 A;  3POX A;  4AYE C;  3UPG A;  2M06 A;  3VZW X;  3FYX A;  1BH3 A;  2Y2X A;  5AFU K;  4O49 A;  4FT6 A;  4XNL A;  3V8U A;  4KR4 A;  4O3X B;  4AKR B;  4O3Y A;  1GFN A;  4O3Z A;  3AA6 A;  3AA7 B;  4FES A;  1IZN B;  3DA4 A;  4U9C A;  8PRN A;  4AFK A;  3VY8 X;  2Y0L A;  3AAA A;  7PRN A;  1ZHX A;  1BXW A;  4N58 A;  4BUM X;  2XTR A;  4RL9 A;  2XTQ A;  1GFM A;  2F1V A;  4FZL A;  1THQ A;  3EMN X;  2LFU A;  2XE3 A;  4FUV A;  4LSE A;  3PRN A;  5T5F A;  5G26 A;  3POU A;  3POQ A;  3LK2 A;  5D5D A;  1PRN A;  3AAA B;  4F4B A;  1PHO A;  3AA7 A;  2J1N A;  4GHB A;  2XG6 A;  3JTY A;  5GV0 A;  5DL5 A;  4G76 A;  4GCP A;  2K0L A;  2KDY A;  3HWB A;  4AKM A;  2KC0 A;  2GE4 A;  3LK2 B;  2N2M A;  4AYD C;  3SY9 A;  1GFQ A;  2OMF A;  4AYI D;  3NSG A;  1ZHZ A;  6PRN A;  4FMS A;  1E54 A;  3UU2 A;  4GF4 A;  4PUX A;  1P4T A;  1HXT A;  4AYN A;  3GP6 A;  2ZFG A;  4LSF A;  4RLC A;  1BT9 A;  3PQS A;  3VZU X;  3WI4 A;  3AAE A;  2QTK A;  2X27 X;  1OPF A;  3VE1 A;  3SZD A;  3QRC A;  4AYM C;  2N2L A;  2J4U P;  2JMM A;  3C5O A;  3O0E A;  4AUI A;  1MPF A;  2ERV A;  2FGQ X;  5DL7 A;  2KZ7 B;  5ADX L;  5IYU A;  4GCQ A;  2MNH A;  1H6S 1;  3LK3 A;  2ZLD A;  1G90 A;  2F1T A;  2O4V A;  3AAE B;  4E1S A;  1OSM A;  3VY9 X;  4RJX A;  3SYS A;  4FOZ A;  2XE1 A;  2XE2 A;  4FZM A;  1ORM A;  2FGR A;  3G7G A;  3T0S A;  4QQ1 A;  1GFO A;  3SZV A;  4N59 A;  1Q9G A;  3AA0 A;  1QJ9 A;  1Q9F A;  3LK3 B;  2XE5 A;  2YNK A;  2KXP B;  2KZ7 A;  3SYB A;  2MHL A;  3PQU A;  4JCH A;  4Z3T A;  4O3W A;  4G75 A;  4LSI A;  3QRA A;  2XMX A;  4KRA A;  2Y0H A;  3VE2 A;  1HXU A;  3LK4 1;  4O4X A;  2Y0K A;  4XNK A;  1ZHY A;  5ADX K;  4KR8 A;  3T24 A;  4JFB A;  1QJ8 A;  3HW9 A;  3T20 A;  2YPV A;  3AA0 B;  3SY7 A;  3WI5 A;  3RBH A;  3TZG A;  3VZT X;  1ZHW A;  4RLB A;  4E1T A;  2K4T A;  2LHF A;  2POR A;  4FSO A;  5DL6 A;  2KXP A;  3HOL A;  1YS5 A;  5FVN A;  4FRX A;  4O4U A;  3DA3 A;  2Y7S A;  5AFU L;  5DL8 A;  4B61 A;  3UAQ A;  4FZN A;  4D64 A;  3KVD D;  4AZL A;  1ZHT A;  4FSP A;  3AA1 A;  1HXX A;  1MM5 A;  4D65 A;  2W81 C;  4D5U A;  4C69 X;  3K19 A;  4LSH A;  3HOE A;  3POR A;  1QJP A;  4RJW A;  3AA6 B;  1GFP A;  3A2S X;  4AKR A;  5PRN A;  4FRT A;  2W80 C;  1IZN A;  1MM4 A;  2ODJ A;  3LK4 2;  4GCS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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