3EMNX

The crystal structure of mouse vdac1 at 2.3 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
283
structure length
283
Chain Sequence
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating
pubmed doi rcsb
source organism Mus musculus
molecule tags Membrane protein
molecule keywords Voltage-dependent anion-selective channel protein 1
total genus 63
structure length 283
sequence length 283
ec nomenclature
pdb deposition date 2008-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 3emnX00
5DL5A 1OSMA 1HXXA 5FVNA 2PORA 4LSIA 4D64A 3VY9X 4FSOA 5DL6A 2PRNA 2Y0HA 4KR4A 1OPFA 4AUIA 3SZVA 2XG6A 4FRXA 3VZUX 4C69X 3UPGA 1GFNA 1E54A 3POQA 3EMNX 2FGRA 4D65A 2FGQX 5DL7A 4FT6A 2ZLDA 4BUMX 4FRTA 4FSPA 4LSFA 2XE2A 5PRNA 4RJXA 4GCSA 4KR8A 3JTYA 1H6S1 1GFMA 8PRNA 4LSHA 1BT9A 3T0SA 4LSEA 2K4TA 2XE5A 1PRNA 4JFBA 4GCQA 3VZTX 3T20A 6PRNA 2J4UP 4D5UA 3T24A 4RJWA 3SYSA 2OMFA 3K19A 3VY8X 3SYBA 2Y0LA 3VZWX 3WI5A 2O4VA 2Y2XA 3PORA 3SY7A 3SZDA 2ZFGA 2J1NA 4GCPA 1GFPA 3POUA 3POXA 3PRNA 1GFQA 3FYXA 1PHOA 3HW9A 3A2SX 1GFOA 3HWBA 5DL8A 3WI4A 2XE3A 3NSGA 7PRNA 2QTKA 1MPFA 2ODJA 3UU2A 1HXTA 3O0EA 4KRAA 5JDPA 3SY9A 2XE1A 4FMSA 1BH3A 2Y0KA 1HXUA 4FOZA
chains in the Genus database with same CATH superfamily
4E1SA 3G7GA 1OSMA 4FZMA 5DL5A 1HXXA 2KC0A 2PORA 3AA1B 2R4NA 1ZHXA 2YNKA 4LSIA 5FVNA 4AKRB 4D64A 2K0LA 2N2MA 2W81C 3VY9X 4O49A 4UB8O 3LK2B 4FSOA 2Y7SA 2IWVA 5DL6A 2WJRA 5G39A 2PRNA 3AA6B 3NJTA 2Y0HA 4KR4A 3DWNA 4RL9A 4FZNA 5AFUK 3WU2O 4E1TA 4AYID 2GE4A 5GTHO 1OPFA 4AUIA 4C00A 1S5LO 2ERVA 5G38A 4QQ1A 3A0HO 3KZIO 3SZVA 3VE1A 2JMMA 2XG6A 2JQYA 3AAEA 4FRXA 4G76A 5G26A 4Z3TA 3VZUX 2YPVA 2XMXA 4C69X 3LK2A 4RLBA 3AA0A 4C4VB 3UPGA 1GFNA 1E54A 1Q9FA 3POQA 1T16A 3EMNX 4FUVA 4PJ0O 4B61A 2R4LA 1IZNB 2X9KA 1THQA 2FGRA 3LK3B 3PGSA 1YS5A 1T1LA 4IL6O 2FGQX 4GHBA 5DL7A 4FT6A 4AYEC 3PF1A 5TISO 4O4UA 2F1TA 3TZGA 1G90A 1ZHWA 2ZLDA 2M06A 3BS0A 4BUMX 3DA4A 1QJPA 2KXPA 3KVDD 3PQSA 4GF4A 4FRTA 4FSPA 5GV0A 2R8AA 4LSFA 2XE2A 2KZ7A 5PRNA 5KAIO 3AA7A 3AA6A 4RJXA 5H2FO 3BRYA 2R4PA 4GCSA 3LK42 4KR8A 4G75A 2LFUA 3JTYA 3UAQA 4AKMA 3AA7B 1H6S1 1GFMA 3HOLA 4C4VA 8PRNA 5ADXK 3LK41 4LSHA 4O3YA 1BT9A 1ZHZA 3AAAA 4K3CA 2K4TA 3JCUO 4LSEA 2XE5A 3T0SA 4CTDA 4FQEA 2MNHA 1P4TA 2R88A 4U9CA 1PRNA 4JFBA 4N59A 5GTIO 4GCQA 3VZTX 4F4BA 3AA0B 4AYNA 3T20A 2W80C 3AA1A 2F1CX 6PRNA 2J4UP 3PGRA 2XTQA 3LK3A 2F1VA 4RLCA 2IWWA 2LHFA 4D5UA 3T24A 4D65A 3C5OA 4RJWA 3SYSA 2OMFA 2X27X 3AAEB 3DZMA 3K19A 2N2LA 4O3ZA 3VY8X 1BXWA 4AZLA 3SYBA 2Y0LA 5IYUA 3VZWX 2KXPB 2XTRA 3BRZA 3RBHA 3WI5A 4AKRA 3AAAB 2O4VA 3GP6A 1IZNA 2Y2XA 3PORA 4XNKA 3SY7A 2ZFGA 2J1NA 4GCPA 3SZDA 5KAFO 4AYMC 1GFPA 3POUA 5B5EO 3DA3A 3POXA 4N58A 4XNLA 2WJQA 5G3AA 3PRNA 4FZLA 5AFUL 1GFQA 5ADXL 1QJ9A 1ZHTA 1ZHYA 2R4OA 4N74A 3FYXA 1PHOA 3HW9A 5B66O 3A2SX 1GFOA 3HOEA 4N75A 4PR7A 2KZ7B 3HWBA 5D5DA 5DL8A 3WI4A 5T5FA 2XE3A 1Q9GA 3NSGA 3PGUA 7PRNA 4K3BA 4O4XA 2QTKA 1MM5A 1MM4A 1MPFA 3QRAA 1ORMA 4O3XB 2ODJA 3QRCA 3DWOX 3UU2A 1QJ8A 2KDYA 4PUXA 4JCHA 1HXTA 3O0EA 2AXTO 4FESA 4KRAA 4UB6O 5E79O 3SY9A 3V8UA 3VE2A 4AYDC 5JDPA 2M07A 4AFKA 2R89A 2XE1A 3A0BO 3PQUA 4FMSA 2WVPA 1BH3A 4O3WA 5EE2A 2MHLA 2Y0KA 1HXUA 4FOZA
chains in the Genus database with same CATH topology
4E1SA 3G7GA 1OSMA 4FZMA 5DL5A 1HXXA 2KC0A 2PORA 3AA1B 4LSIA 1ZHXA 2YNKA 5FVNA 4AKRB 4D64A 2K0LA 2N2MA 2W81C 3VY9X 4O49A 3LK2B 4FSOA 2Y7SA 5DL6A 2PRNA 3AA6B 2Y0HA 4KR4A 4RL9A 4FZNA 5AFUK 4AYID 2GE4A 1OPFA 4AUIA 2ERVA 4QQ1A 3SZVA 3VE1A 2JMMA 2XG6A 3AAEA 4FRXA 4G76A 5G26A 4Z3TA 3VZUX 2YPVA 2XMXA 4C69X 3LK2A 4RLBA 3AA0A 3UPGA 1GFNA 1E54A 1Q9FA 3POQA 4FUVA 3EMNX 4B61A 1IZNB 1THQA 2FGRA 3LK3B 4D65A 1YS5A 2FGQX 4GHBA 5DL7A 4FT6A 4AYEC 4O4UA 2F1TA 3TZGA 1G90A 1ZHWA 2ZLDA 2M06A 4BUMX 3DA4A 1QJPA 2KXPA 3KVDD 3PQSA 4GF4A 4FRTA 4FSPA 5GV0A 4LSFA 2XE2A 2KZ7A 5PRNA 3AA7A 3AA6A 4RJXA 4GCSA 3LK42 4KR8A 4G75A 2LFUA 3JTYA 3UAQA 4AKMA 3AA7B 1H6S1 1GFMA 3HOLA 8PRNA 5ADXK 3LK41 4LSHA 4O3YA 1BT9A 1ZHZA 3AAAA 4LSEA 2K4TA 3T0SA 2XE5A 2MNHA 1P4TA 4U9CA 1PRNA 4JFBA 4N59A 4GCQA 3VZTX 4F4BA 3AA0B 4AYNA 3T20A 2W80C 3AA1A 6PRNA 2J4UP 2XTQA 3LK3A 2F1VA 4RLCA 2LHFA 4D5UA 3T24A 3C5OA 4RJWA 3SYSA 2OMFA 2X27X 3AAEB 3K19A 4O3ZA 2N2LA 3VY8X 4AZLA 1BXWA 3SYBA 2Y0LA 5IYUA 3VZWX 2KXPB 2XTRA 3RBHA 3WI5A 4AKRA 3AAAB 2O4VA 3GP6A 1IZNA 2Y2XA 3PORA 4XNKA 3SY7A 2ZFGA 2J1NA 4GCPA 3SZDA 4AYMC 4E1TA 1GFPA 3POUA 3DA3A 3POXA 4N58A 4XNLA 3PRNA 4FZLA 5AFUL 1GFQA 5ADXL 1QJ9A 1ZHTA 1ZHYA 3FYXA 1PHOA 3HW9A 3A2SX 1GFOA 3HOEA 5D5DA 2KZ7B 3HWBA 5DL8A 3WI4A 5T5FA 2XE3A 1Q9GA 3NSGA 7PRNA 4O4XA 2QTKA 1MM5A 1MM4A 1MPFA 3QRAA 1ORMA 4O3XB 2ODJA 3QRCA 3UU2A 1QJ8A 2KDYA 4PUXA 4JCHA 1HXTA 3O0EA 4FESA 4KRAA 3V8UA 4AYDC 3SY9A 3VE2A 5JDPA 2M07A 4AFKA 2XE1A 3PQUA 4FMSA 5EE2A 1BH3A 4O3WA 2MHLA 2Y0KA 1HXUA 4FOZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DL5 A;  1OSM A;  1HXX A;  5FVN A;  2POR A;  4LSI A;  4D64 A;  3VY9 X;  4FSO A;  5DL6 A;  2PRN A;  2Y0H A;  4KR4 A;  1OPF A;  4AUI A;  3SZV A;  2XG6 A;  4FRX A;  3VZU X;  4C69 X;  3UPG A;  1GFN A;  1E54 A;  3POQ A;  3EMN X;  2FGR A;  4D65 A;  2FGQ X;  5DL7 A;  4FT6 A;  2ZLD A;  4BUM X;  4FRT A;  4FSP A;  4LSF A;  2XE2 A;  5PRN A;  4RJX A;  4GCS A;  4KR8 A;  3JTY A;  1H6S 1;  1GFM A;  8PRN A;  4LSH A;  1BT9 A;  3T0S A;  4LSE A;  2K4T A;  2XE5 A;  1PRN A;  4JFB A;  4GCQ A;  3VZT X;  3T20 A;  6PRN A;  2J4U P;  4D5U A;  3T24 A;  4RJW A;  3SYS A;  2OMF A;  3K19 A;  3VY8 X;  3SYB A;  2Y0L A;  3VZW X;  3WI5 A;  2O4V A;  2Y2X A;  3POR A;  3SY7 A;  3SZD A;  2ZFG A;  2J1N A;  4GCP A;  1GFP A;  3POU A;  3POX A;  3PRN A;  1GFQ A;  3FYX A;  1PHO A;  3HW9 A;  3A2S X;  1GFO A;  3HWB A;  5DL8 A;  3WI4 A;  2XE3 A;  3NSG A;  7PRN A;  2QTK A;  1MPF A;  2ODJ A;  3UU2 A;  1HXT A;  3O0E A;  4KRA A;  5JDP A;  3SY9 A;  2XE1 A;  4FMS A;  1BH3 A;  2Y0K A;  1HXU A;  4FOZ A; 
#chains in the Genus database with same CATH topology
 4E1S A;  3G7G A;  1OSM A;  4FZM A;  5DL5 A;  1HXX A;  2KC0 A;  2POR A;  3AA1 B;  2R4N A;  1ZHX A;  2YNK A;  4LSI A;  5FVN A;  4AKR B;  4D64 A;  2K0L A;  2N2M A;  2W81 C;  3VY9 X;  4O49 A;  4UB8 O;  3LK2 B;  4FSO A;  2Y7S A;  2IWV A;  5DL6 A;  2WJR A;  5G39 A;  2PRN A;  3AA6 B;  3NJT A;  2Y0H A;  4KR4 A;  3DWN A;  4RL9 A;  4FZN A;  5AFU K;  3WU2 O;  4E1T A;  4AYI D;  2GE4 A;  5GTH O;  1OPF A;  4AUI A;  4C00 A;  1S5L O;  2ERV A;  5G38 A;  4QQ1 A;  3A0H O;  3KZI O;  3SZV A;  3VE1 A;  2JMM A;  2XG6 A;  2JQY A;  3AAE A;  4FRX A;  4G76 A;  5G26 A;  4Z3T A;  3VZU X;  2YPV A;  2XMX A;  4C69 X;  3LK2 A;  4RLB A;  3AA0 A;  4C4V B;  3UPG A;  1GFN A;  1E54 A;  1Q9F A;  3POQ A;  1T16 A;  3EMN X;  4FUV A;  4PJ0 O;  4B61 A;  2R4L A;  1IZN B;  2X9K A;  1THQ A;  2FGR A;  3LK3 B;  3PGS A;  1YS5 A;  1T1L A;  4IL6 O;  2FGQ X;  4GHB A;  5DL7 A;  4FT6 A;  4AYE C;  3PF1 A;  5TIS O;  4O4U A;  2F1T A;  3TZG A;  1G90 A;  1ZHW A;  2ZLD A;  2M06 A;  3BS0 A;  4BUM X;  3DA4 A;  1QJP A;  2KXP A;  3KVD D;  3PQS A;  4GF4 A;  4FRT A;  4FSP A;  5GV0 A;  2R8A A;  4LSF A;  2XE2 A;  2KZ7 A;  5PRN A;  5KAI O;  3AA7 A;  3AA6 A;  4RJX A;  5H2F O;  3BRY A;  2R4P A;  4GCS A;  3LK4 2;  4KR8 A;  4G75 A;  2LFU A;  3JTY A;  3UAQ A;  4AKM A;  3AA7 B;  1H6S 1;  1GFM A;  3HOL A;  4C4V A;  8PRN A;  5ADX K;  3LK4 1;  4LSH A;  4O3Y A;  1BT9 A;  1ZHZ A;  3AAA A;  4K3C A;  2K4T A;  3JCU O;  4LSE A;  2XE5 A;  3T0S A;  4CTD A;  4FQE A;  2MNH A;  1P4T A;  2R88 A;  4U9C A;  1PRN A;  4JFB A;  4N59 A;  5GTI O;  4GCQ A;  3VZT X;  4F4B A;  3AA0 B;  4AYN A;  3T20 A;  2W80 C;  3AA1 A;  2F1C X;  6PRN A;  2J4U P;  3PGR A;  2XTQ A;  3LK3 A;  2F1V A;  4RLC A;  2IWW A;  2LHF A;  4D5U A;  3T24 A;  4D65 A;  3C5O A;  4RJW A;  3SYS A;  2OMF A;  2X27 X;  3AAE B;  3DZM A;  3K19 A;  2N2L A;  4O3Z A;  3VY8 X;  1BXW A;  4AZL A;  3SYB A;  2Y0L A;  5IYU A;  3VZW X;  2KXP B;  2XTR A;  3BRZ A;  3RBH A;  3WI5 A;  4AKR A;  3AAA B;  2O4V A;  3GP6 A;  1IZN A;  2Y2X A;  3POR A;  4XNK A;  3SY7 A;  2ZFG A;  2J1N A;  4GCP A;  3SZD A;  5KAF O;  4AYM C;  1GFP A;  3POU A;  5B5E O;  3DA3 A;  3POX A;  4N58 A;  4XNL A;  2WJQ A;  5G3A A;  3PRN A;  4FZL A;  5AFU L;  1GFQ A;  5ADX L;  1QJ9 A;  1ZHT A;  1ZHY A;  2R4O A;  4N74 A;  3FYX A;  1PHO A;  3HW9 A;  5B66 O;  3A2S X;  1GFO A;  3HOE A;  4N75 A;  4PR7 A;  2KZ7 B;  3HWB A;  5D5D A;  5DL8 A;  3WI4 A;  5T5F A;  2XE3 A;  1Q9G A;  3NSG A;  3PGU A;  7PRN A;  4K3B A;  4O4X A;  2QTK A;  1MM5 A;  1MM4 A;  1MPF A;  3QRA A;  1ORM A;  4O3X B;  2ODJ A;  3QRC A;  3DWO X;  3UU2 A;  1QJ8 A;  2KDY A;  4PUX A;  4JCH A;  1HXT A;  3O0E A;  2AXT O;  4FES A;  4KRA A;  4UB6 O;  5E79 O;  3SY9 A;  3V8U A;  3VE2 A;  4AYD C;  5JDP A;  2M07 A;  4AFK A;  2R89 A;  2XE1 A;  3A0B O;  3PQU A;  4FMS A;  2WVP A;  1BH3 A;  4O3W A;  5EE2 A;  2MHL A;  2Y0K A;  1HXU A;  4FOZ A; 
#chains in the Genus database with same CATH homology
 4E1S A;  3G7G A;  1OSM A;  4FZM A;  5DL5 A;  1HXX A;  2KC0 A;  2POR A;  3AA1 B;  4LSI A;  1ZHX A;  2YNK A;  5FVN A;  4AKR B;  4D64 A;  2K0L A;  2N2M A;  2W81 C;  3VY9 X;  4O49 A;  3LK2 B;  4FSO A;  2Y7S A;  5DL6 A;  2PRN A;  3AA6 B;  2Y0H A;  4KR4 A;  4RL9 A;  4FZN A;  5AFU K;  4AYI D;  2GE4 A;  1OPF A;  4AUI A;  2ERV A;  4QQ1 A;  3SZV A;  3VE1 A;  2JMM A;  2XG6 A;  3AAE A;  4FRX A;  4G76 A;  5G26 A;  4Z3T A;  3VZU X;  2YPV A;  2XMX A;  4C69 X;  3LK2 A;  4RLB A;  3AA0 A;  3UPG A;  1GFN A;  1E54 A;  1Q9F A;  3POQ A;  4FUV A;  3EMN X;  4B61 A;  1IZN B;  1THQ A;  2FGR A;  3LK3 B;  4D65 A;  1YS5 A;  2FGQ X;  4GHB A;  5DL7 A;  4FT6 A;  4AYE C;  4O4U A;  2F1T A;  3TZG A;  1G90 A;  1ZHW A;  2ZLD A;  2M06 A;  4BUM X;  3DA4 A;  1QJP A;  2KXP A;  3KVD D;  3PQS A;  4GF4 A;  4FRT A;  4FSP A;  5GV0 A;  4LSF A;  2XE2 A;  2KZ7 A;  5PRN A;  3AA7 A;  3AA6 A;  4RJX A;  4GCS A;  3LK4 2;  4KR8 A;  4G75 A;  2LFU A;  3JTY A;  3UAQ A;  4AKM A;  3AA7 B;  1H6S 1;  1GFM A;  3HOL A;  8PRN A;  5ADX K;  3LK4 1;  4LSH A;  4O3Y A;  1BT9 A;  1ZHZ A;  3AAA A;  4LSE A;  2K4T A;  3T0S A;  2XE5 A;  2MNH A;  1P4T A;  4U9C A;  1PRN A;  4JFB A;  4N59 A;  4GCQ A;  3VZT X;  4F4B A;  3AA0 B;  4AYN A;  3T20 A;  2W80 C;  3AA1 A;  6PRN A;  2J4U P;  2XTQ A;  3LK3 A;  2F1V A;  4RLC A;  2LHF A;  4D5U A;  3T24 A;  3C5O A;  4RJW A;  3SYS A;  2OMF A;  2X27 X;  3AAE B;  3K19 A;  4O3Z A;  2N2L A;  3VY8 X;  4AZL A;  1BXW A;  3SYB A;  2Y0L A;  5IYU A;  3VZW X;  2KXP B;  2XTR A;  3RBH A;  3WI5 A;  4AKR A;  3AAA B;  2O4V A;  3GP6 A;  1IZN A;  2Y2X A;  3POR A;  4XNK A;  3SY7 A;  2ZFG A;  2J1N A;  4GCP A;  3SZD A;  4AYM C;  4E1T A;  1GFP A;  3POU A;  3DA3 A;  3POX A;  4N58 A;  4XNL A;  3PRN A;  4FZL A;  5AFU L;  1GFQ A;  5ADX L;  1QJ9 A;  1ZHT A;  1ZHY A;  3FYX A;  1PHO A;  3HW9 A;  3A2S X;  1GFO A;  3HOE A;  5D5D A;  2KZ7 B;  3HWB A;  5DL8 A;  3WI4 A;  5T5F A;  2XE3 A;  1Q9G A;  3NSG A;  7PRN A;  4O4X A;  2QTK A;  1MM5 A;  1MM4 A;  1MPF A;  3QRA A;  1ORM A;  4O3X B;  2ODJ A;  3QRC A;  3UU2 A;  1QJ8 A;  2KDY A;  4PUX A;  4JCH A;  1HXT A;  3O0E A;  4FES A;  4KRA A;  3V8U A;  4AYD C;  3SY9 A;  3VE2 A;  5JDP A;  2M07 A;  4AFK A;  2XE1 A;  3PQU A;  4FMS A;  5EE2 A;  1BH3 A;  4O3W A;  2MHL A;  2Y0K A;  1HXU A;  4FOZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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