3EMNX

The crystal structure of mouse vdac1 at 2.3 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
283
structure length
283
Chain Sequence
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Voltage-dependent anion-selective channel protein 1
publication title The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating
pubmed doi rcsb
source organism Mus musculus
molecule tags Membrane protein
total genus 63
structure length 283
sequence length 283
ec nomenclature
pdb deposition date 2008-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 3emnX00
1OPFA 4FMSA 4FSOA 2Y2XA 1GFPA 4C69X 4FRTA 2ZFGA 3FYXA 1HXTA 1GFMA 2XE5A 4FRXA 2ZLDA 3HW9A 4KR4A 2ODJA 8PRNA 2Y0KA 3T24A 2QTKA 4BUMX 2FGRA 1HXXA 3SYSA 4GCQA 2XE1A 3VZTX 5DL7A 3VY9X 2PORA 5DL8A 2XG6A 4LSHA 4D5UA 2PRNA 2Y0LA 1OSMA 7PRNA 1GFNA 4AUIA 4RJWA 2XE2A 5DL5A 4GCPA 4KR8A 5JDPA 3K19A 3POQA 4RJXA 4D65A 5FVNA 3A2SX 3EMNX 3T20A 1MPFA 2K4TA 3SY7A 3VZWX 2J4UP 3UPGA 4FT6A 5PRNA 1BT9A 1GFOA 3SYBA 4LSFA 3POUA 2XE3A 3PORA 3WI5A 2J1NA 3UU2A 2FGQX 4JFBA 2OMFA 2Y0HA 4LSIA 6PRNA 1BH3A 1PRNA 3O0EA 4FSPA 1PHOA 4FOZA 4GCSA 4KRAA 3T0SA 1E54A 3SZVA 3SY9A 4D64A 3PRNA 4LSEA 1H6S1 2O4VA 3SZDA 3NSGA 1HXUA 3WI4A 3VZUX 3HWBA 3JTYA 5DL6A 1GFQA 3VY8X 3POXA
chains in the Genus database with same CATH superfamily
1OPFA 4O3ZA 4FMSA 4FSOA 3AA1A 2YPVA 4O49A 1QJPA 4K3CA 2Y2XA 3RBHA 1GFPA 4AFKA 3PGUA 3PQUA 2AXTO 3A0BO 4C69X 1MM5A 5IYUA 2K0LA 4FRTA 3BRYA 2ZFGA 2YNKA 1HXTA 2R89A 3FYXA 1IZNA 4AYNA 1GFMA 5ADXK 3PGSA 3TZGA 2XE5A 5B66O 4FRXA 3AAAA 2ZLDA 2N2LA 4AYDC 3HW9A 2R88A 4KR4A 2KDYA 2MHLA 2ODJA 3AA7A 8PRNA 3LK42 3DZMA 1QJ9A 2W80C 1YS5A 2Y0KA 3KZIO 2WVPA 4FZNA 4AKMA 3T24A 2QTKA 3WU2O 4BUMX 2FGRA 1HXXA 5TISO 4O3YA 3LK2A 2GE4A 3SYSA 3DA4A 4F4BA 4GCQA 5T5FA 3GP6A 4AZLA 2XE1A 4O3XB 4RLCA 5H2FO 1BXWA 2W81C 2X9KA 3VZTX 4AKRB 5DL7A 3VY9X 1G90A 2PORA 4PR7A 5DL8A 2XG6A 2M07A 4LSHA 4D5UA 4E1SA 1ZHWA 2PRNA 5D5DA 2XTRA 2X27X 5GV0A 2R4OA 1ORMA 2Y0LA 1S5LO 3QRCA 4JCHA 3UAQA 4N75A 2IWWA 2N2MA 4QQ1A 5EE2A 2M06A 1OSMA 7PRNA 1GFNA 4AUIA 4RJWA 2XE2A 3VE2A 3PF1A 3VE1A 3HOEA 5DL5A 2R4NA 2R4PA 3AAEB 4C00A 4C4VB 4GCPA 4KR8A 5JDPA 3K19A 5ADXL 2R4LA 4XNLA 3POQA 4RJXA 4D65A 2IWVA 2KZ7B 4B61A 1ZHXA 4FESA 2LHFA 3A2SX 5FVNA 4N74A 2MNHA 3EMNX 3T20A 1MPFA 1IZNB 5AFUL 2K4TA 4AYEC 4RLBA 3BS0A 3SY7A 4GHBA 3VZWX 3HOLA 3NJTA 5DL6A 2KC0A 3LK3B 2J4UP 4FZMA 4FT6A 4AKRA 5PRNA 3UPGA 5G3AA 5KAFO 4UB8O 1BT9A 1Q9GA 4U9CA 1GFOA 3LK41 3SYBA 3AA7B 4AYID 4LSFA 5B5EO 2WJQA 3AA0B 3POUA 2ERVA 2XE3A 2XMXA 3AA6B 2KXPB 3KVDD 3PORA 4N59A 3DA3A 3LK2B 3WI5A 2J1NA 3UU2A 2FGQX 3DWOX 5E79O 3DWNA 4JFBA 2OMFA 2Y0HA 3QRAA 4LSIA 6PRNA 3AA1B 3G7GA 1BH3A 1PRNA 3O0EA 4UB6O 4FSPA 1PHOA 4FOZA 3PGRA 2LFUA 4FUVA 4XNKA 3AAEA 4C4VA 4PJ0O 1Q9FA 4IL6O 4GCSA 4KRAA 4E1TA 4FQEA 5G38A 3T0SA 2Y7SA 1E54A 2KZ7A 4GF4A 4K3BA 3PQSA 3SZVA 3SY9A 3C5OA 1MM4A 4PUXA 4D64A 1QJ8A 1ZHYA 3PRNA 4LSEA 4AYMC 1H6S1 3A0HO 2O4VA 2JQYA 2F1VA 3AAAB 4CTDA 3SZDA 3V8UA 4Z3TA 3NSGA 2JMMA 3LK3A 1HXUA 4G76A 4N58A 4O4UA 5AFUK 1T16A 1T1LA 1THQA 5KAIO 4O4XA 3WI4A 5G26A 1ZHTA 5G39A 3VZUX 2XTQA 4FZLA 5GTIO 5GTHO 3AA0A 3HWBA 2R8AA 2F1TA 3AA6A 2F1CX 1GFQA 2KXPA 1P4TA 2WJRA 3BRZA 3JTYA 4O3WA 4G75A 3VY8X 1ZHZA 3JCUO 3POXA 4RL9A
chains in the Genus database with same CATH topology
1OPFA 4O3ZA 4FMSA 4FSOA 3AA1A 2YPVA 4O49A 1QJPA 2Y2XA 3RBHA 1GFPA 4AFKA 3PQUA 4C69X 5IYUA 1MM5A 2K0LA 4FRTA 2ZFGA 2YNKA 1HXTA 3FYXA 1IZNA 4AYNA 1GFMA 5ADXK 3TZGA 2XE5A 4FRXA 3AAAA 2ZLDA 2N2LA 4AYDC 3HW9A 4KR4A 2KDYA 2MHLA 2ODJA 3AA7A 8PRNA 3LK42 1QJ9A 2W80C 1YS5A 2Y0KA 4AKMA 4FZNA 3T24A 2QTKA 4BUMX 2FGRA 1HXXA 4O3YA 3LK2A 2GE4A 3SYSA 3DA4A 4F4BA 4GCQA 5T5FA 3GP6A 4AZLA 2XE1A 4O3XB 4RLCA 1BXWA 2W81C 3VZTX 4AKRB 5DL7A 3VY9X 1G90A 2PORA 5DL8A 2XG6A 2M07A 4LSHA 4D5UA 4E1SA 1ZHWA 2PRNA 5D5DA 2XTRA 2X27X 5GV0A 1ORMA 2Y0LA 3QRCA 4JCHA 3UAQA 2N2MA 4QQ1A 5EE2A 2M06A 1OSMA 7PRNA 1GFNA 4AUIA 4RJWA 2XE2A 3VE2A 3VE1A 3HOEA 5DL5A 3AAEB 4GCPA 4KR8A 5JDPA 3K19A 5ADXL 4XNLA 3POQA 4RJXA 4D65A 2KZ7B 4B61A 1ZHXA 4FESA 2LHFA 3A2SX 5FVNA 2MNHA 3EMNX 3T20A 1MPFA 1IZNB 5AFUL 2K4TA 4AYEC 4RLBA 3SY7A 3VZWX 4GHBA 3HOLA 2KC0A 3LK3B 2J4UP 4FZMA 4FT6A 4AKRA 5PRNA 3UPGA 1BT9A 1Q9GA 4U9CA 1GFOA 3LK41 3SYBA 3AA7B 4AYID 4LSFA 3AA0B 3POUA 2ERVA 2XE3A 2XMXA 3AA6B 2KXPB 3KVDD 3PORA 4N59A 3DA3A 3LK2B 3WI5A 2J1NA 3UU2A 2FGQX 4JFBA 2OMFA 2Y0HA 3QRAA 4LSIA 6PRNA 3AA1B 3G7GA 1BH3A 1PRNA 3O0EA 4FSPA 1PHOA 4FOZA 2LFUA 4FUVA 4XNKA 3AAEA 1Q9FA 4E1TA 4GCSA 4KRAA 3T0SA 2Y7SA 1E54A 2KZ7A 4GF4A 3PQSA 3SZVA 3SY9A 3C5OA 1MM4A 4PUXA 4D64A 1QJ8A 1ZHYA 3PRNA 4LSEA 4AYMC 1H6S1 2O4VA 3AAAB 2F1VA 4Z3TA 3SZDA 3V8UA 3NSGA 2JMMA 3LK3A 1HXUA 4G76A 4N58A 4O4UA 5AFUK 1THQA 4O4XA 3WI4A 5G26A 1ZHTA 3VZUX 2XTQA 4FZLA 3AA0A 3HWBA 3AA6A 2F1TA 3JTYA 4O3WA 1GFQA 2KXPA 1P4TA 5DL6A 4G75A 3VY8X 1ZHZA 3POXA 4RL9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OPF A;  4FMS A;  4FSO A;  2Y2X A;  1GFP A;  4C69 X;  4FRT A;  2ZFG A;  3FYX A;  1HXT A;  1GFM A;  2XE5 A;  4FRX A;  2ZLD A;  3HW9 A;  4KR4 A;  2ODJ A;  8PRN A;  2Y0K A;  3T24 A;  2QTK A;  4BUM X;  2FGR A;  1HXX A;  3SYS A;  4GCQ A;  2XE1 A;  3VZT X;  5DL7 A;  3VY9 X;  2POR A;  5DL8 A;  2XG6 A;  4LSH A;  4D5U A;  2PRN A;  2Y0L A;  1OSM A;  7PRN A;  1GFN A;  4AUI A;  4RJW A;  2XE2 A;  5DL5 A;  4GCP A;  4KR8 A;  5JDP A;  3K19 A;  3POQ A;  4RJX A;  4D65 A;  5FVN A;  3A2S X;  3EMN X;  3T20 A;  1MPF A;  2K4T A;  3SY7 A;  3VZW X;  2J4U P;  3UPG A;  4FT6 A;  5PRN A;  1BT9 A;  1GFO A;  3SYB A;  4LSF A;  3POU A;  2XE3 A;  3POR A;  3WI5 A;  2J1N A;  3UU2 A;  2FGQ X;  4JFB A;  2OMF A;  2Y0H A;  4LSI A;  6PRN A;  1BH3 A;  1PRN A;  3O0E A;  4FSP A;  1PHO A;  4FOZ A;  4GCS A;  4KRA A;  3T0S A;  1E54 A;  3SZV A;  3SY9 A;  4D64 A;  3PRN A;  4LSE A;  1H6S 1;  2O4V A;  3SZD A;  3NSG A;  1HXU A;  3WI4 A;  3VZU X;  3HWB A;  3JTY A;  5DL6 A;  1GFQ A;  3VY8 X;  3POX A; 
#chains in the Genus database with same CATH topology
 1OPF A;  4O3Z A;  4FMS A;  4FSO A;  3AA1 A;  2YPV A;  4O49 A;  1QJP A;  4K3C A;  2Y2X A;  3RBH A;  1GFP A;  4AFK A;  3PGU A;  3PQU A;  2AXT O;  3A0B O;  4C69 X;  1MM5 A;  5IYU A;  2K0L A;  4FRT A;  3BRY A;  2ZFG A;  2YNK A;  1HXT A;  2R89 A;  3FYX A;  1IZN A;  4AYN A;  1GFM A;  5ADX K;  3PGS A;  3TZG A;  2XE5 A;  5B66 O;  4FRX A;  3AAA A;  2ZLD A;  2N2L A;  4AYD C;  3HW9 A;  2R88 A;  4KR4 A;  2KDY A;  2MHL A;  2ODJ A;  3AA7 A;  8PRN A;  3LK4 2;  3DZM A;  1QJ9 A;  2W80 C;  1YS5 A;  2Y0K A;  3KZI O;  2WVP A;  4FZN A;  4AKM A;  3T24 A;  2QTK A;  3WU2 O;  4BUM X;  2FGR A;  1HXX A;  5TIS O;  4O3Y A;  3LK2 A;  2GE4 A;  3SYS A;  3DA4 A;  4F4B A;  4GCQ A;  5T5F A;  3GP6 A;  4AZL A;  2XE1 A;  4O3X B;  4RLC A;  5H2F O;  1BXW A;  2W81 C;  2X9K A;  3VZT X;  4AKR B;  5DL7 A;  3VY9 X;  1G90 A;  2POR A;  4PR7 A;  5DL8 A;  2XG6 A;  2M07 A;  4LSH A;  4D5U A;  4E1S A;  1ZHW A;  2PRN A;  5D5D A;  2XTR A;  2X27 X;  5GV0 A;  2R4O A;  1ORM A;  2Y0L A;  1S5L O;  3QRC A;  4JCH A;  3UAQ A;  4N75 A;  2IWW A;  2N2M A;  4QQ1 A;  5EE2 A;  2M06 A;  1OSM A;  7PRN A;  1GFN A;  4AUI A;  4RJW A;  2XE2 A;  3VE2 A;  3PF1 A;  3VE1 A;  3HOE A;  5DL5 A;  2R4N A;  2R4P A;  3AAE B;  4C00 A;  4C4V B;  4GCP A;  4KR8 A;  5JDP A;  3K19 A;  5ADX L;  2R4L A;  4XNL A;  3POQ A;  4RJX A;  4D65 A;  2IWV A;  2KZ7 B;  4B61 A;  1ZHX A;  4FES A;  2LHF A;  3A2S X;  5FVN A;  4N74 A;  2MNH A;  3EMN X;  3T20 A;  1MPF A;  1IZN B;  5AFU L;  2K4T A;  4AYE C;  4RLB A;  3BS0 A;  3SY7 A;  4GHB A;  3VZW X;  3HOL A;  3NJT A;  5DL6 A;  2KC0 A;  3LK3 B;  2J4U P;  4FZM A;  4FT6 A;  4AKR A;  5PRN A;  3UPG A;  5G3A A;  5KAF O;  4UB8 O;  1BT9 A;  1Q9G A;  4U9C A;  1GFO A;  3LK4 1;  3SYB A;  3AA7 B;  4AYI D;  4LSF A;  5B5E O;  2WJQ A;  3AA0 B;  3POU A;  2ERV A;  2XE3 A;  2XMX A;  3AA6 B;  2KXP B;  3KVD D;  3POR A;  4N59 A;  3DA3 A;  3LK2 B;  3WI5 A;  2J1N A;  3UU2 A;  2FGQ X;  3DWO X;  5E79 O;  3DWN A;  4JFB A;  2OMF A;  2Y0H A;  3QRA A;  4LSI A;  6PRN A;  3AA1 B;  3G7G A;  1BH3 A;  1PRN A;  3O0E A;  4UB6 O;  4FSP A;  1PHO A;  4FOZ A;  3PGR A;  2LFU A;  4FUV A;  4XNK A;  3AAE A;  4C4V A;  4PJ0 O;  1Q9F A;  4IL6 O;  4GCS A;  4KRA A;  4E1T A;  4FQE A;  5G38 A;  3T0S A;  2Y7S A;  1E54 A;  2KZ7 A;  4GF4 A;  4K3B A;  3PQS A;  3SZV A;  3SY9 A;  3C5O A;  1MM4 A;  4PUX A;  4D64 A;  1QJ8 A;  1ZHY A;  3PRN A;  4LSE A;  4AYM C;  1H6S 1;  3A0H O;  2O4V A;  2JQY A;  2F1V A;  3AAA B;  4CTD A;  3SZD A;  3V8U A;  4Z3T A;  3NSG A;  2JMM A;  3LK3 A;  1HXU A;  4G76 A;  4N58 A;  4O4U A;  5AFU K;  1T16 A;  1T1L A;  1THQ A;  5KAI O;  4O4X A;  3WI4 A;  5G26 A;  1ZHT A;  5G39 A;  3VZU X;  2XTQ A;  4FZL A;  5GTI O;  5GTH O;  3AA0 A;  3HWB A;  2R8A A;  2F1T A;  3AA6 A;  2F1C X;  1GFQ A;  2KXP A;  1P4T A;  2WJR A;  3BRZ A;  3JTY A;  4O3W A;  4G75 A;  3VY8 X;  1ZHZ A;  3JCU O;  3POX A;  4RL9 A; 
#chains in the Genus database with same CATH homology
 1OPF A;  4O3Z A;  4FMS A;  4FSO A;  3AA1 A;  2YPV A;  4O49 A;  1QJP A;  2Y2X A;  3RBH A;  1GFP A;  4AFK A;  3PQU A;  4C69 X;  5IYU A;  1MM5 A;  2K0L A;  4FRT A;  2ZFG A;  2YNK A;  1HXT A;  3FYX A;  1IZN A;  4AYN A;  1GFM A;  5ADX K;  3TZG A;  2XE5 A;  4FRX A;  3AAA A;  2ZLD A;  2N2L A;  4AYD C;  3HW9 A;  4KR4 A;  2KDY A;  2MHL A;  2ODJ A;  3AA7 A;  8PRN A;  3LK4 2;  1QJ9 A;  2W80 C;  1YS5 A;  2Y0K A;  4AKM A;  4FZN A;  3T24 A;  2QTK A;  4BUM X;  2FGR A;  1HXX A;  4O3Y A;  3LK2 A;  2GE4 A;  3SYS A;  3DA4 A;  4F4B A;  4GCQ A;  5T5F A;  3GP6 A;  4AZL A;  2XE1 A;  4O3X B;  4RLC A;  1BXW A;  2W81 C;  3VZT X;  4AKR B;  5DL7 A;  3VY9 X;  1G90 A;  2POR A;  5DL8 A;  2XG6 A;  2M07 A;  4LSH A;  4D5U A;  4E1S A;  1ZHW A;  2PRN A;  5D5D A;  2XTR A;  2X27 X;  5GV0 A;  1ORM A;  2Y0L A;  3QRC A;  4JCH A;  3UAQ A;  2N2M A;  4QQ1 A;  5EE2 A;  2M06 A;  1OSM A;  7PRN A;  1GFN A;  4AUI A;  4RJW A;  2XE2 A;  3VE2 A;  3VE1 A;  3HOE A;  5DL5 A;  3AAE B;  4GCP A;  4KR8 A;  5JDP A;  3K19 A;  5ADX L;  4XNL A;  3POQ A;  4RJX A;  4D65 A;  2KZ7 B;  4B61 A;  1ZHX A;  4FES A;  2LHF A;  3A2S X;  5FVN A;  2MNH A;  3EMN X;  3T20 A;  1MPF A;  1IZN B;  5AFU L;  2K4T A;  4AYE C;  4RLB A;  3SY7 A;  3VZW X;  4GHB A;  3HOL A;  2KC0 A;  3LK3 B;  2J4U P;  4FZM A;  4FT6 A;  4AKR A;  5PRN A;  3UPG A;  1BT9 A;  1Q9G A;  4U9C A;  1GFO A;  3LK4 1;  3SYB A;  3AA7 B;  4AYI D;  4LSF A;  3AA0 B;  3POU A;  2ERV A;  2XE3 A;  2XMX A;  3AA6 B;  2KXP B;  3KVD D;  3POR A;  4N59 A;  3DA3 A;  3LK2 B;  3WI5 A;  2J1N A;  3UU2 A;  2FGQ X;  4JFB A;  2OMF A;  2Y0H A;  3QRA A;  4LSI A;  6PRN A;  3AA1 B;  3G7G A;  1BH3 A;  1PRN A;  3O0E A;  4FSP A;  1PHO A;  4FOZ A;  2LFU A;  4FUV A;  4XNK A;  3AAE A;  1Q9F A;  4E1T A;  4GCS A;  4KRA A;  3T0S A;  2Y7S A;  1E54 A;  2KZ7 A;  4GF4 A;  3PQS A;  3SZV A;  3SY9 A;  3C5O A;  1MM4 A;  4PUX A;  4D64 A;  1QJ8 A;  1ZHY A;  3PRN A;  4LSE A;  4AYM C;  1H6S 1;  2O4V A;  3AAA B;  2F1V A;  4Z3T A;  3SZD A;  3V8U A;  3NSG A;  2JMM A;  3LK3 A;  1HXU A;  4G76 A;  4N58 A;  4O4U A;  5AFU K;  1THQ A;  4O4X A;  3WI4 A;  5G26 A;  1ZHT A;  3VZU X;  2XTQ A;  4FZL A;  3AA0 A;  3HWB A;  3AA6 A;  2F1T A;  3JTY A;  4O3W A;  1GFQ A;  2KXP A;  1P4T A;  5DL6 A;  4G75 A;  3VY8 X;  1ZHZ A;  3POX A;  4RL9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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