2XE5A

Molecular insights into clinically isolated ompc mutants and their role in multi-drug resistance (ompc26)
Total Genus 101
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
343
structure length
343
Chain Sequence
AEIYNKDGNKLDLYGKVEGLHYFSDNDSKDGDKTYMRLGFKGETQVTDQLTGYGQWEYQIQGNEPESDNSSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYDSDNFMQQRGNGFATYRNTDFFGLVDGLDFAVQYQGKNGSAHGEGMTTNGRDDVFEQNGDGVGGSITYNYEGFGIGAAVSSSKRTWDQNNTGLIGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNRFTRDAGINTDDIVALGLVYQF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords OUTER MEMBRANE PORIN C
total genus 101
structure length 343
sequence length 343
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2010-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00267 Porin_1 Gram-negative porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 2xe5A00
2J4UP 3O0EA 4RJXA 3SYBA 4LSHA 2ODJA 4FSOA 1HXXA 5DL8A 3HW9A 3VZWX 1GFNA 3WI5A 3POUA 2ZLDA 4AUIA 3POQA 1GFOA 4GCSA 4KR8A 2XE5A 2Y0KA 3PRNA 5PRNA 3SZDA 2XG6A 4LSEA 5DL5A 3T20A 4FRTA 2PORA 4FSPA 3VZUX 5DL6A 3VZTX 6PRNA 1OSMA 2O4VA 2FGQX 1HXTA 1BH3A 3SZVA 3POXA 4KR4A 4GCQA 5DL7A 4BUMX 3NSGA 4FRXA 1PHOA 1GFPA 1GFMA 3T24A 3T0SA 4D65A 2FGRA 4D5UA 4LSFA 2XE2A 4FOZA 4LSIA 2J1NA 2K4TA 4FMSA 3FYXA 4D64A 3WI4A 3SYSA 3UPGA 3EMNX 1MPFA 2XE1A 2Y0HA 8PRNA 1E54A 2ZFGA 3PORA 4GCPA 1HXUA 2OMFA 2QTKA 2Y2XA 4JFBA 5JDPA 2XE3A 3UU2A 2Y0LA 2PRNA 1GFQA 3VY9X 3A2SX 3K19A 7PRNA 1PRNA 3VY8X 4C69X 4FT6A 4RJWA 3JTYA 3HWBA 5FVNA 1BT9A 4KRAA 3SY9A 1OPFA 3SY7A 1H6S1
chains in the Genus database with same CATH superfamily
5KAFO 2XTRA 3AAAA 4PR7A 3WU2O 3PGRA 2J4UP 2XMXA 3AA1B 2KXPA 3O0EA 4XNLA 4AYID 4RJXA 3SYBA 4AYDC 2R4LA 4FQEA 3LK2A 4LSHA 3LK3B 4IL6O 5G26A 2X27X 2ODJA 3AA0A 4FSOA 1HXXA 2N2MA 3LK41 2F1CX 3QRAA 5DL8A 1IZNA 3KZIO 4N74A 3HW9A 3VZWX 1YS5A 1GFNA 3VE2A 3WI5A 3POUA 2ZLDA 4G76A 4AUIA 3POQA 3QRCA 4O3YA 2M07A 2GE4A 1GFOA 3PQUA 4GCSA 3RBHA 2KXPB 5ADXL 5IYUA 5E79O 1T16A 3DA4A 3AA7B 3BS0A 3PGSA 4KR8A 3LK3A 4PUXA 3VE1A 3UAQA 5T5FA 2XE5A 2Y0KA 3PRNA 5PRNA 5GV0A 3SZDA 2ERVA 4C00A 2XG6A 3DZMA 4FZMA 4LSEA 5D5DA 1P4TA 5DL5A 4FRTA 3T20A 2F1TA 3C5OA 2LHFA 4CTDA 3BRYA 2PORA 4O4XA 4FSPA 4RL9A 3BRZA 1MM4A 4AKMA 3AA7A 1T1LA 3VZUX 5DL6A 3VZTX 5ADXK 2KC0A 6PRNA 5EE2A 1Q9FA 4UB6O 2R88A 1OSMA 2O4VA 5GTIO 2IWVA 4O3ZA 2AXTO 2FGQX 4N58A 3A0HO 1HXTA 1BH3A 2MNHA 3SZVA 2X9KA 3POXA 4KR4A 4XNKA 3JCUO 4QQ1A 2W80C 4GCQA 2YPVA 4O49A 5DL7A 2K0LA 4BUMX 4F4BA 3TZGA 3AAEA 1MM5A 5AFUL 3NSGA 2LFUA 4FRXA 1PHOA 4AZLA 2JQYA 1QJ8A 1GFPA 1GFMA 3AA6B 4U9CA 3T0SA 3T24A 4D65A 2FGRA 1G90A 4AFKA 4AYEC 2IWWA 1QJ9A 4D5UA 1QJPA 4LSFA 5GTHO 2XE2A 4K3BA 2JMMA 4O3WA 4FOZA 5B5EO 3PGUA 4LSIA 3A0BO 2J1NA 3AAEB 5G3AA 1S5LO 2K4TA 3HOEA 4FMSA 4UB8O 4K3CA 3FYXA 2KZ7B 3PQSA 5TISO 4D64A 5AFUK 3AA6A 4Z3TA 3V8UA 3WI4A 4C4VB 3SYSA 5B66O 3UPGA 2XTQA 3EMNX 1MPFA 2XE1A 2Y0HA 5G38A 3GP6A 4FESA 8PRNA 2WJRA 1E54A 2ZFGA 2R4NA 3PORA 4FZLA 4GCPA 1HXUA 4E1TA 4AYNA 2OMFA 2MHLA 4PJ0O 2QTKA 2Y2XA 4JFBA 3LK42 5JDPA 2XE3A 2N2LA 3UU2A 2KDYA 4RLBA 2Y0LA 2PRNA 5KAIO 2KZ7A 4GF4A 2F1VA 4B61A 1BXWA 4C4VA 2R4OA 5H2FO 1GFQA 1Q9GA 2R89A 2W81C 3A2SX 4RLCA 3VY9X 4O4UA 4AKRB 3DWOX 1ZHXA 3K19A 7PRNA 4GHBA 3KVDD 1THQA 2WVPA 4G75A 4JCHA 1ZHWA 4FZNA 1PRNA 2WJQA 1ZHYA 2YNKA 4O3XB 3HOLA 3AAAB 4N59A 3VY8X 3G7GA 3AA1A 4FT6A 4FUVA 4C69X 4E1SA 3NJTA 4RJWA 2R8AA 3DA3A 3LK2B 4N75A 4AKRA 3DWNA 3AA0B 3JTYA 2Y7SA 1ORMA 3HWBA 1BT9A 4KRAA 5FVNA 1OPFA 1IZNB 5G39A 3SY9A 4AYMC 2R4PA 1ZHTA 3SY7A 1H6S1 1ZHZA 2M06A 3PF1A
chains in the Genus database with same CATH topology
2XTRA 3AAAA 2J4UP 2XMXA 3AA1B 2KXPA 3O0EA 4XNLA 4AYID 4RJXA 3SYBA 4AYDC 3LK2A 4LSHA 3LK3B 5G26A 2X27X 2ODJA 3AA0A 4FSOA 1HXXA 2N2MA 3LK41 3QRAA 5DL8A 1IZNA 3HW9A 3VZWX 1YS5A 1GFNA 3VE2A 3WI5A 3POUA 2ZLDA 4G76A 4AUIA 3POQA 3QRCA 4O3YA 2M07A 2GE4A 1GFOA 3PQUA 4GCSA 3RBHA 2KXPB 5ADXL 5IYUA 3DA4A 3AA7B 4KR8A 3LK3A 4PUXA 3VE1A 3UAQA 5T5FA 2XE5A 2Y0KA 3PRNA 5PRNA 5GV0A 3SZDA 2ERVA 2XG6A 4FZMA 4LSEA 5D5DA 1P4TA 5DL5A 4FRTA 3T20A 2F1TA 3C5OA 2LHFA 2PORA 4O4XA 4FSPA 4RL9A 1MM4A 4AKMA 3AA7A 3VZUX 5ADXK 5DL6A 3VZTX 2KC0A 6PRNA 5EE2A 1Q9FA 1OSMA 2O4VA 4O3ZA 2FGQX 4N58A 1HXTA 1BH3A 2MNHA 3SZVA 3POXA 4KR4A 4XNKA 4QQ1A 2W80C 4GCQA 2YPVA 4O49A 5DL7A 2K0LA 4BUMX 4F4BA 3TZGA 3AAEA 1MM5A 5AFUL 3NSGA 2LFUA 4FRXA 1PHOA 4AZLA 1QJ8A 1GFPA 1GFMA 3AA6B 4U9CA 3T0SA 3T24A 4D65A 2FGRA 1G90A 4AFKA 4AYEC 1QJ9A 4D5UA 1QJPA 4LSFA 2XE2A 2JMMA 4O3WA 4FOZA 4LSIA 2J1NA 3AAEB 2K4TA 3HOEA 4FMSA 3FYXA 2KZ7B 3PQSA 4D64A 5AFUK 3AA6A 4Z3TA 3V8UA 3WI4A 3SYSA 3UPGA 2XTQA 3EMNX 1MPFA 2XE1A 2Y0HA 8PRNA 3GP6A 4FESA 1E54A 2ZFGA 3PORA 4FZLA 4GCPA 4E1TA 1HXUA 4AYNA 2OMFA 2MHLA 2QTKA 2Y2XA 4JFBA 3LK42 5JDPA 2XE3A 2N2LA 3UU2A 2KDYA 4RLBA 2Y0LA 2PRNA 2KZ7A 4GF4A 2F1VA 4B61A 1BXWA 1GFQA 1Q9GA 2W81C 3A2SX 4RLCA 3VY9X 4O4UA 4AKRB 1ZHXA 3K19A 7PRNA 4GHBA 3KVDD 1THQA 4G75A 4JCHA 1ZHWA 4FZNA 1PRNA 1ZHYA 2YNKA 4O3XB 3HOLA 3AAAB 4N59A 3VY8X 3G7GA 3AA1A 4FT6A 4FUVA 4C69X 4E1SA 4RJWA 3DA3A 3LK2B 4AKRA 3AA0B 3JTYA 2Y7SA 1ORMA 3HWBA 1BT9A 4KRAA 5FVNA 1OPFA 1IZNB 3SY9A 4AYMC 1ZHTA 3SY7A 1H6S1 1ZHZA 2M06A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J4U P;  3O0E A;  4RJX A;  3SYB A;  4LSH A;  2ODJ A;  4FSO A;  1HXX A;  5DL8 A;  3HW9 A;  3VZW X;  1GFN A;  3WI5 A;  3POU A;  2ZLD A;  4AUI A;  3POQ A;  1GFO A;  4GCS A;  4KR8 A;  2XE5 A;  2Y0K A;  3PRN A;  5PRN A;  3SZD A;  2XG6 A;  4LSE A;  5DL5 A;  3T20 A;  4FRT A;  2POR A;  4FSP A;  3VZU X;  5DL6 A;  3VZT X;  6PRN A;  1OSM A;  2O4V A;  2FGQ X;  1HXT A;  1BH3 A;  3SZV A;  3POX A;  4KR4 A;  4GCQ A;  5DL7 A;  4BUM X;  3NSG A;  4FRX A;  1PHO A;  1GFP A;  1GFM A;  3T24 A;  3T0S A;  4D65 A;  2FGR A;  4D5U A;  4LSF A;  2XE2 A;  4FOZ A;  4LSI A;  2J1N A;  2K4T A;  4FMS A;  3FYX A;  4D64 A;  3WI4 A;  3SYS A;  3UPG A;  3EMN X;  1MPF A;  2XE1 A;  2Y0H A;  8PRN A;  1E54 A;  2ZFG A;  3POR A;  4GCP A;  1HXU A;  2OMF A;  2QTK A;  2Y2X A;  4JFB A;  5JDP A;  2XE3 A;  3UU2 A;  2Y0L A;  2PRN A;  1GFQ A;  3VY9 X;  3A2S X;  3K19 A;  7PRN A;  1PRN A;  3VY8 X;  4C69 X;  4FT6 A;  4RJW A;  3JTY A;  3HWB A;  5FVN A;  1BT9 A;  4KRA A;  3SY9 A;  1OPF A;  3SY7 A;  1H6S 1; 
#chains in the Genus database with same CATH topology
 5KAF O;  2XTR A;  3AAA A;  4PR7 A;  3WU2 O;  3PGR A;  2J4U P;  2XMX A;  3AA1 B;  2KXP A;  3O0E A;  4XNL A;  4AYI D;  4RJX A;  3SYB A;  4AYD C;  2R4L A;  4FQE A;  3LK2 A;  4LSH A;  3LK3 B;  4IL6 O;  5G26 A;  2X27 X;  2ODJ A;  3AA0 A;  4FSO A;  1HXX A;  2N2M A;  3LK4 1;  2F1C X;  3QRA A;  5DL8 A;  1IZN A;  3KZI O;  4N74 A;  3HW9 A;  3VZW X;  1YS5 A;  1GFN A;  3VE2 A;  3WI5 A;  3POU A;  2ZLD A;  4G76 A;  4AUI A;  3POQ A;  3QRC A;  4O3Y A;  2M07 A;  2GE4 A;  1GFO A;  3PQU A;  4GCS A;  3RBH A;  2KXP B;  5ADX L;  5IYU A;  5E79 O;  1T16 A;  3DA4 A;  3AA7 B;  3BS0 A;  3PGS A;  4KR8 A;  3LK3 A;  4PUX A;  3VE1 A;  3UAQ A;  5T5F A;  2XE5 A;  2Y0K A;  3PRN A;  5PRN A;  5GV0 A;  3SZD A;  2ERV A;  4C00 A;  2XG6 A;  3DZM A;  4FZM A;  4LSE A;  5D5D A;  1P4T A;  5DL5 A;  4FRT A;  3T20 A;  2F1T A;  3C5O A;  2LHF A;  4CTD A;  3BRY A;  2POR A;  4O4X A;  4FSP A;  4RL9 A;  3BRZ A;  1MM4 A;  4AKM A;  3AA7 A;  1T1L A;  3VZU X;  5DL6 A;  3VZT X;  5ADX K;  2KC0 A;  6PRN A;  5EE2 A;  1Q9F A;  4UB6 O;  2R88 A;  1OSM A;  2O4V A;  5GTI O;  2IWV A;  4O3Z A;  2AXT O;  2FGQ X;  4N58 A;  3A0H O;  1HXT A;  1BH3 A;  2MNH A;  3SZV A;  2X9K A;  3POX A;  4KR4 A;  4XNK A;  3JCU O;  4QQ1 A;  2W80 C;  4GCQ A;  2YPV A;  4O49 A;  5DL7 A;  2K0L A;  4BUM X;  4F4B A;  3TZG A;  3AAE A;  1MM5 A;  5AFU L;  3NSG A;  2LFU A;  4FRX A;  1PHO A;  4AZL A;  2JQY A;  1QJ8 A;  1GFP A;  1GFM A;  3AA6 B;  4U9C A;  3T0S A;  3T24 A;  4D65 A;  2FGR A;  1G90 A;  4AFK A;  4AYE C;  2IWW A;  1QJ9 A;  4D5U A;  1QJP A;  4LSF A;  5GTH O;  2XE2 A;  4K3B A;  2JMM A;  4O3W A;  4FOZ A;  5B5E O;  3PGU A;  4LSI A;  3A0B O;  2J1N A;  3AAE B;  5G3A A;  1S5L O;  2K4T A;  3HOE A;  4FMS A;  4UB8 O;  4K3C A;  3FYX A;  2KZ7 B;  3PQS A;  5TIS O;  4D64 A;  5AFU K;  3AA6 A;  4Z3T A;  3V8U A;  3WI4 A;  4C4V B;  3SYS A;  5B66 O;  3UPG A;  2XTQ A;  3EMN X;  1MPF A;  2XE1 A;  2Y0H A;  5G38 A;  3GP6 A;  4FES A;  8PRN A;  2WJR A;  1E54 A;  2ZFG A;  2R4N A;  3POR A;  4FZL A;  4GCP A;  1HXU A;  4E1T A;  4AYN A;  2OMF A;  2MHL A;  4PJ0 O;  2QTK A;  2Y2X A;  4JFB A;  3LK4 2;  5JDP A;  2XE3 A;  2N2L A;  3UU2 A;  2KDY A;  4RLB A;  2Y0L A;  2PRN A;  5KAI O;  2KZ7 A;  4GF4 A;  2F1V A;  4B61 A;  1BXW A;  4C4V A;  2R4O A;  5H2F O;  1GFQ A;  1Q9G A;  2R89 A;  2W81 C;  3A2S X;  4RLC A;  3VY9 X;  4O4U A;  4AKR B;  3DWO X;  1ZHX A;  3K19 A;  7PRN A;  4GHB A;  3KVD D;  1THQ A;  2WVP A;  4G75 A;  4JCH A;  1ZHW A;  4FZN A;  1PRN A;  2WJQ A;  1ZHY A;  2YNK A;  4O3X B;  3HOL A;  3AAA B;  4N59 A;  3VY8 X;  3G7G A;  3AA1 A;  4FT6 A;  4FUV A;  4C69 X;  4E1S A;  3NJT A;  4RJW A;  2R8A A;  3DA3 A;  3LK2 B;  4N75 A;  4AKR A;  3DWN A;  3AA0 B;  3JTY A;  2Y7S A;  1ORM A;  3HWB A;  1BT9 A;  4KRA A;  5FVN A;  1OPF A;  1IZN B;  5G39 A;  3SY9 A;  4AYM C;  2R4P A;  1ZHT A;  3SY7 A;  1H6S 1;  1ZHZ A;  2M06 A;  3PF1 A; 
#chains in the Genus database with same CATH homology
 2XTR A;  3AAA A;  2J4U P;  2XMX A;  3AA1 B;  2KXP A;  3O0E A;  4XNL A;  4AYI D;  4RJX A;  3SYB A;  4AYD C;  3LK2 A;  4LSH A;  3LK3 B;  5G26 A;  2X27 X;  2ODJ A;  3AA0 A;  4FSO A;  1HXX A;  2N2M A;  3LK4 1;  3QRA A;  5DL8 A;  1IZN A;  3HW9 A;  3VZW X;  1YS5 A;  1GFN A;  3VE2 A;  3WI5 A;  3POU A;  2ZLD A;  4G76 A;  4AUI A;  3POQ A;  3QRC A;  4O3Y A;  2M07 A;  2GE4 A;  1GFO A;  3PQU A;  4GCS A;  3RBH A;  2KXP B;  5ADX L;  5IYU A;  3DA4 A;  3AA7 B;  4KR8 A;  3LK3 A;  4PUX A;  3VE1 A;  3UAQ A;  5T5F A;  2XE5 A;  2Y0K A;  3PRN A;  5PRN A;  5GV0 A;  3SZD A;  2ERV A;  2XG6 A;  4FZM A;  4LSE A;  5D5D A;  1P4T A;  5DL5 A;  4FRT A;  3T20 A;  2F1T A;  3C5O A;  2LHF A;  2POR A;  4O4X A;  4FSP A;  4RL9 A;  1MM4 A;  4AKM A;  3AA7 A;  3VZU X;  5ADX K;  5DL6 A;  3VZT X;  2KC0 A;  6PRN A;  5EE2 A;  1Q9F A;  1OSM A;  2O4V A;  4O3Z A;  2FGQ X;  4N58 A;  1HXT A;  1BH3 A;  2MNH A;  3SZV A;  3POX A;  4KR4 A;  4XNK A;  4QQ1 A;  2W80 C;  4GCQ A;  2YPV A;  4O49 A;  5DL7 A;  2K0L A;  4BUM X;  4F4B A;  3TZG A;  3AAE A;  1MM5 A;  5AFU L;  3NSG A;  2LFU A;  4FRX A;  1PHO A;  4AZL A;  1QJ8 A;  1GFP A;  1GFM A;  3AA6 B;  4U9C A;  3T0S A;  3T24 A;  4D65 A;  2FGR A;  1G90 A;  4AFK A;  4AYE C;  1QJ9 A;  4D5U A;  1QJP A;  4LSF A;  2XE2 A;  2JMM A;  4O3W A;  4FOZ A;  4LSI A;  2J1N A;  3AAE B;  2K4T A;  3HOE A;  4FMS A;  3FYX A;  2KZ7 B;  3PQS A;  4D64 A;  5AFU K;  3AA6 A;  4Z3T A;  3V8U A;  3WI4 A;  3SYS A;  3UPG A;  2XTQ A;  3EMN X;  1MPF A;  2XE1 A;  2Y0H A;  8PRN A;  3GP6 A;  4FES A;  1E54 A;  2ZFG A;  3POR A;  4FZL A;  4GCP A;  4E1T A;  1HXU A;  4AYN A;  2OMF A;  2MHL A;  2QTK A;  2Y2X A;  4JFB A;  3LK4 2;  5JDP A;  2XE3 A;  2N2L A;  3UU2 A;  2KDY A;  4RLB A;  2Y0L A;  2PRN A;  2KZ7 A;  4GF4 A;  2F1V A;  4B61 A;  1BXW A;  1GFQ A;  1Q9G A;  2W81 C;  3A2S X;  4RLC A;  3VY9 X;  4O4U A;  4AKR B;  1ZHX A;  3K19 A;  7PRN A;  4GHB A;  3KVD D;  1THQ A;  4G75 A;  4JCH A;  1ZHW A;  4FZN A;  1PRN A;  1ZHY A;  2YNK A;  4O3X B;  3HOL A;  3AAA B;  4N59 A;  3VY8 X;  3G7G A;  3AA1 A;  4FT6 A;  4FUV A;  4C69 X;  4E1S A;  4RJW A;  3DA3 A;  3LK2 B;  4AKR A;  3AA0 B;  3JTY A;  2Y7S A;  1ORM A;  3HWB A;  1BT9 A;  4KRA A;  5FVN A;  1OPF A;  1IZN B;  3SY9 A;  4AYM C;  1ZHT A;  3SY7 A;  1H6S 1;  1ZHZ A;  2M06 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...