1P4TA

Crystal structure of neisserial surface protein a (nspa)
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
155
structure length
155
Chain Sequence
EGASGFYVQADAAHAKASSSLGSAKGFSPRISAGYRINDLRFAVDYTRYKNYKAPSTDFKLYSIGASAIYDFDTQSPVKPYLGARLSLNRASVDLGGSDSFSQTSIGLGVLTGVSYAVTPNVDLDAGYRYNYIGKVNTVKNVRSGELSAGVRVKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Neisserial Surface Protein A (NspA), a conserved outer membrane protein with vaccine potential
pubmed doi rcsb
molecule tags Membrane protein
source organism Neisseria meningitidis
molecule keywords outer membrane protein NspA
total genus 40
structure length 155
sequence length 155
ec nomenclature
pdb deposition date 2003-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02462 Opacity Opacity family porin protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.20 Mainly Beta Beta Barrel Porin Porin 1p4tA00
2N2LA 2F1TA 3QRAA 3G7GA 1Q9GA 2X27X 1QJ9A 1Q9FA 1BXWA 1ORMA 2ERVA 3QRCA 1P4TA 4RLCA 3GP6A 1THQA 2GE4A 2MHLA 2JMMA 3C5OA 1MM4A 2K0LA 2N2MA 2MNHA 2F1VA 1MM5A 1G90A 2LHFA 1QJPA 2M06A 2M07A 1QJ8A 4PUXA
chains in the Genus database with same CATH superfamily
2KZ7A 3JTYA 4FQEA 4FSPA 5GV0A 3AA6B 4U9CA 1YS5A 3NSGA 3LK3A 1ZHYA 3G7GA 4K3CA 4KR4A 3A2SX 4C69X 4C4VA 2X27X 2R4OA 3WI4A 4PR7A 3BRZA 2R4NA 4E1SA 3QRCA 3BS0A 3PGUA 2FGQX 4AYNA 1P4TA 3DWNA 4BUMX 3UPGA 3GP6A 3UU2A 1GFNA 2KZ7B 2AXTO 2J1NA 2MHLA 4FZLA 4XNKA 4AYDC 5B5EO 1HXUA 1MM4A 3LK3B 1GFPA 4N58A 2N2MA 1HXXA 3POQA 4RJXA 2MNHA 4G76A 3HWBA 4UB8O 6PRNA 4D64A 5GTIO 3TZGA 2M06A 2M07A 3PORA 4IL6O 2R4PA 4AYEC 3A0BO 4PJ0O 1ZHTA 1PHOA 4GHBA 5DL5A 2N2LA 2KXPA 4RL9A 4AZLA 2R4LA 2X9KA 5PRNA 3PF1A 3DA4A 4O49A 3PRNA 4AKRA 3K19A 5DL6A 1S5LO 3AA0B 4K3BA 1QJ9A 4C00A 1MPFA 2XG6A 4FRXA 2ERVA 3SZVA 5H2FO 3NJTA 3POUA 2F1CX 3AAAB 1T16A 2O4VA 3HW9A 5TISO 4CTDA 4QQ1A 3VE1A 5DL8A 3PQSA 5D5DA 2KXPB 3A0HO 4FMSA 4JCHA 3T20A 2JMMA 2JQYA 4Z3TA 3DWOX 3C5OA 2Y0KA 3DA3A 4AKRB 4FT6A 4FUVA 5G26A 1PRNA 3PQUA 3AA0A 4AYMC 4FRTA 2ZFGA 1MM5A 1GFMA 3KVDD 1IZNA 4JFBA 2LHFA 1QJPA 4O3ZA 4PUXA 3T24A 5EE2A 3AAAA 4FESA 4E1TA 3DZMA 4AYID 2QTKA 1GFQA 2WJQA 4O3XB 5AFUL 1Q9GA 4LSHA 3SZDA 3VZTX 4KRAA 1ZHWA 4N74A 4LSEA 2YPVA 2ODJA 2R8AA 3WU2O 3PGRA 4FSOA 1IZNB 1OSMA 3SYBA 3VZUX 3HOLA 5B66O 4RLCA 4B61A 5ADXK 2XE1A 4O4XA 4AUIA 1E54A 3JCUO 3LK41 2PRNA 5KAIO 2K0LA 2K4TA 4GF4A 1H6S1 4O4UA 2R88A 5E79O 3SYSA 2XE3A 1OPFA 5ADXL 2Y7SA 2IWVA 5T5FA 3POXA 5FVNA 4UB6O 4XNLA 5AFUK 3HOEA 3O0EA 4FZNA 2FGRA 2Y2XA 2PORA 4LSFA 4RJWA 4F4BA 1T1LA 2WVPA 3VY9X 2F1TA 3BRYA 2ZLDA 3QRAA 3RBHA 5DL7A 4GCPA 4D65A 3AAEB 3EMNX 4N59A 3AA7A 1ZHZA 3V8UA 4FOZA 2XE2A 2Y0LA 4O3YA 1BT9A 3T0SA 3AA1B 1HXTA 2LFUA 3VZWX 4FZMA 3FYXA 2XTRA 3LK2B 2WJRA 4O3WA 1Q9FA 1BXWA 4GCQA 1ORMA 3PGSA 7PRNA 2J4UP 5G3AA 4AKMA 2W80C 4AFKA 2KC0A 3UAQA 5GTHO 3SY9A 1THQA 2XE5A 4LSIA 4D5UA 5JDPA 3SY7A 2GE4A 3AA6A 1GFOA 3VE2A 4GCSA 3WI5A 2YNKA 4N75A 4C4VB 2R89A 3AA7B 3AAEA 5G39A 2KDYA 2XTQA 4RLBA 4KR8A 4G75A 5G38A 5KAFO 8PRNA 3AA1A 2F1VA 2Y0HA 3VY8X 1ZHXA 2W81C 3LK2A 2IWWA 5IYUA 1BH3A 3LK42 1G90A 2XMXA 1QJ8A 3KZIO 2OMFA
chains in the Genus database with same CATH topology
2KZ7A 3JTYA 4FSPA 5GV0A 3AA6B 4U9CA 1YS5A 3NSGA 3LK3A 1ZHYA 3G7GA 4KR4A 3A2SX 4C69X 2X27X 3WI4A 4E1SA 3QRCA 2FGQX 4AYNA 1P4TA 4BUMX 3UPGA 3GP6A 3UU2A 1GFNA 2KZ7B 2J1NA 2MHLA 4FZLA 4XNKA 4AYDC 1HXUA 1MM4A 3LK3B 1GFPA 4N58A 2N2MA 1HXXA 3POQA 4RJXA 2MNHA 4G76A 3HWBA 6PRNA 4D64A 3TZGA 2M06A 2M07A 3PORA 4AYEC 1ZHTA 1PHOA 4GHBA 5DL5A 2N2LA 2KXPA 4RL9A 4AZLA 5PRNA 3DA4A 4O49A 3PRNA 4AKRA 3K19A 5DL6A 3AA0B 1QJ9A 1MPFA 2XG6A 4FRXA 2ERVA 3SZVA 3POUA 3AAAB 2O4VA 3HW9A 4QQ1A 3VE1A 5DL8A 3PQSA 5D5DA 2KXPB 4JCHA 4FMSA 3T20A 2JMMA 4Z3TA 3C5OA 2Y0KA 3DA3A 4AKRB 4FT6A 4FUVA 5G26A 1PRNA 3PQUA 3AA0A 4AYMC 4FRTA 2ZFGA 1MM5A 1GFMA 3KVDD 1IZNA 4JFBA 2LHFA 1QJPA 4O3ZA 4PUXA 3T24A 5EE2A 3AAAA 4FESA 4E1TA 4AYID 2QTKA 1GFQA 4O3XB 5AFUL 1Q9GA 4LSHA 3SZDA 4KRAA 1ZHWA 4LSEA 2YPVA 2ODJA 3VZUX 4FSOA 1IZNB 1OSMA 3SYBA 3HOLA 4RLCA 4B61A 5ADXK 2XE1A 4O4XA 4AUIA 1E54A 3LK41 2PRNA 3SYSA 2K0LA 2K4TA 4GF4A 1H6S1 4O4UA 3VZTX 2XE3A 1OPFA 5ADXL 2Y7SA 5T5FA 3POXA 5FVNA 4XNLA 5AFUK 3HOEA 3O0EA 4FZNA 2FGRA 2Y2XA 2PORA 4LSFA 4RJWA 4F4BA 3VY9X 2F1TA 3QRAA 2ZLDA 3RBHA 4D65A 5DL7A 4GCPA 3AAEB 3EMNX 4N59A 3AA7A 1ZHZA 3V8UA 4FOZA 2XE2A 2Y0LA 4O3YA 1BT9A 3T0SA 3AA1B 1HXTA 2LFUA 3VZWX 4FZMA 3FYXA 2XTRA 3LK2B 4O3WA 1Q9FA 1BXWA 4GCQA 1ORMA 2J4UP 7PRNA 4AKMA 2W80C 4AFKA 2KC0A 3UAQA 3SY9A 1THQA 2XE5A 4LSIA 4D5UA 5JDPA 3SY7A 2GE4A 3AA6A 1GFOA 3VE2A 4GCSA 3WI5A 2YNKA 3AA7B 3AAEA 2KDYA 2XTQA 4RLBA 4KR8A 4G75A 8PRNA 3AA1A 2F1VA 2Y0HA 3VY8X 1ZHXA 2W81C 3LK2A 1G90A 5IYUA 1BH3A 3LK42 2XMXA 1QJ8A 2OMFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N2L A;  2F1T A;  3QRA A;  3G7G A;  1Q9G A;  2X27 X;  1QJ9 A;  1Q9F A;  1BXW A;  1ORM A;  2ERV A;  3QRC A;  1P4T A;  4RLC A;  3GP6 A;  1THQ A;  2GE4 A;  2MHL A;  2JMM A;  3C5O A;  1MM4 A;  2K0L A;  2N2M A;  2MNH A;  2F1V A;  1MM5 A;  1G90 A;  2LHF A;  1QJP A;  2M06 A;  2M07 A;  1QJ8 A;  4PUX A; 
#chains in the Genus database with same CATH topology
 2KZ7 A;  3JTY A;  4FQE A;  4FSP A;  5GV0 A;  3AA6 B;  4U9C A;  1YS5 A;  3NSG A;  3LK3 A;  1ZHY A;  3G7G A;  4K3C A;  4KR4 A;  3A2S X;  4C69 X;  4C4V A;  2X27 X;  2R4O A;  3WI4 A;  4PR7 A;  3BRZ A;  2R4N A;  4E1S A;  3QRC A;  3BS0 A;  3PGU A;  2FGQ X;  4AYN A;  1P4T A;  3DWN A;  4BUM X;  3UPG A;  3GP6 A;  3UU2 A;  1GFN A;  2KZ7 B;  2AXT O;  2J1N A;  2MHL A;  4FZL A;  4XNK A;  4AYD C;  5B5E O;  1HXU A;  1MM4 A;  3LK3 B;  1GFP A;  4N58 A;  2N2M A;  1HXX A;  3POQ A;  4RJX A;  2MNH A;  4G76 A;  3HWB A;  4UB8 O;  6PRN A;  4D64 A;  5GTI O;  3TZG A;  2M06 A;  2M07 A;  3POR A;  4IL6 O;  2R4P A;  4AYE C;  3A0B O;  4PJ0 O;  1ZHT A;  1PHO A;  4GHB A;  5DL5 A;  2N2L A;  2KXP A;  4RL9 A;  4AZL A;  2R4L A;  2X9K A;  5PRN A;  3PF1 A;  3DA4 A;  4O49 A;  3PRN A;  4AKR A;  3K19 A;  5DL6 A;  1S5L O;  3AA0 B;  4K3B A;  1QJ9 A;  4C00 A;  1MPF A;  2XG6 A;  4FRX A;  2ERV A;  3SZV A;  5H2F O;  3NJT A;  3POU A;  2F1C X;  3AAA B;  1T16 A;  2O4V A;  3HW9 A;  5TIS O;  4CTD A;  4QQ1 A;  3VE1 A;  5DL8 A;  3PQS A;  5D5D A;  2KXP B;  3A0H O;  4FMS A;  4JCH A;  3T20 A;  2JMM A;  2JQY A;  4Z3T A;  3DWO X;  3C5O A;  2Y0K A;  3DA3 A;  4AKR B;  4FT6 A;  4FUV A;  5G26 A;  1PRN A;  3PQU A;  3AA0 A;  4AYM C;  4FRT A;  2ZFG A;  1MM5 A;  1GFM A;  3KVD D;  1IZN A;  4JFB A;  2LHF A;  1QJP A;  4O3Z A;  4PUX A;  3T24 A;  5EE2 A;  3AAA A;  4FES A;  4E1T A;  3DZM A;  4AYI D;  2QTK A;  1GFQ A;  2WJQ A;  4O3X B;  5AFU L;  1Q9G A;  4LSH A;  3SZD A;  3VZT X;  4KRA A;  1ZHW A;  4N74 A;  4LSE A;  2YPV A;  2ODJ A;  2R8A A;  3WU2 O;  3PGR A;  4FSO A;  1IZN B;  1OSM A;  3SYB A;  3VZU X;  3HOL A;  5B66 O;  4RLC A;  4B61 A;  5ADX K;  2XE1 A;  4O4X A;  4AUI A;  1E54 A;  3JCU O;  3LK4 1;  2PRN A;  5KAI O;  2K0L A;  2K4T A;  4GF4 A;  1H6S 1;  4O4U A;  2R88 A;  5E79 O;  3SYS A;  2XE3 A;  1OPF A;  5ADX L;  2Y7S A;  2IWV A;  5T5F A;  3POX A;  5FVN A;  4UB6 O;  4XNL A;  5AFU K;  3HOE A;  3O0E A;  4FZN A;  2FGR A;  2Y2X A;  2POR A;  4LSF A;  4RJW A;  4F4B A;  1T1L A;  2WVP A;  3VY9 X;  2F1T A;  3BRY A;  2ZLD A;  3QRA A;  3RBH A;  5DL7 A;  4GCP A;  4D65 A;  3AAE B;  3EMN X;  4N59 A;  3AA7 A;  1ZHZ A;  3V8U A;  4FOZ A;  2XE2 A;  2Y0L A;  4O3Y A;  1BT9 A;  3T0S A;  3AA1 B;  1HXT A;  2LFU A;  3VZW X;  4FZM A;  3FYX A;  2XTR A;  3LK2 B;  2WJR A;  4O3W A;  1Q9F A;  1BXW A;  4GCQ A;  1ORM A;  3PGS A;  7PRN A;  2J4U P;  5G3A A;  4AKM A;  2W80 C;  4AFK A;  2KC0 A;  3UAQ A;  5GTH O;  3SY9 A;  1THQ A;  2XE5 A;  4LSI A;  4D5U A;  5JDP A;  3SY7 A;  2GE4 A;  3AA6 A;  1GFO A;  3VE2 A;  4GCS A;  3WI5 A;  2YNK A;  4N75 A;  4C4V B;  2R89 A;  3AA7 B;  3AAE A;  5G39 A;  2KDY A;  2XTQ A;  4RLB A;  4KR8 A;  4G75 A;  5G38 A;  5KAF O;  8PRN A;  3AA1 A;  2F1V A;  2Y0H A;  3VY8 X;  1ZHX A;  2W81 C;  3LK2 A;  2IWW A;  5IYU A;  1BH3 A;  3LK4 2;  1G90 A;  2XMX A;  1QJ8 A;  3KZI O;  2OMF A; 
#chains in the Genus database with same CATH homology
 2KZ7 A;  3JTY A;  4FSP A;  5GV0 A;  3AA6 B;  4U9C A;  1YS5 A;  3NSG A;  3LK3 A;  1ZHY A;  3G7G A;  4KR4 A;  3A2S X;  4C69 X;  2X27 X;  3WI4 A;  4E1S A;  3QRC A;  2FGQ X;  4AYN A;  1P4T A;  4BUM X;  3UPG A;  3GP6 A;  3UU2 A;  1GFN A;  2KZ7 B;  2J1N A;  2MHL A;  4FZL A;  4XNK A;  4AYD C;  1HXU A;  1MM4 A;  3LK3 B;  1GFP A;  4N58 A;  2N2M A;  1HXX A;  3POQ A;  4RJX A;  2MNH A;  4G76 A;  3HWB A;  6PRN A;  4D64 A;  3TZG A;  2M06 A;  2M07 A;  3POR A;  4AYE C;  1ZHT A;  1PHO A;  4GHB A;  5DL5 A;  2N2L A;  2KXP A;  4RL9 A;  4AZL A;  5PRN A;  3DA4 A;  4O49 A;  3PRN A;  4AKR A;  3K19 A;  5DL6 A;  3AA0 B;  1QJ9 A;  1MPF A;  2XG6 A;  4FRX A;  2ERV A;  3SZV A;  3POU A;  3AAA B;  2O4V A;  3HW9 A;  4QQ1 A;  3VE1 A;  5DL8 A;  3PQS A;  5D5D A;  2KXP B;  4JCH A;  4FMS A;  3T20 A;  2JMM A;  4Z3T A;  3C5O A;  2Y0K A;  3DA3 A;  4AKR B;  4FT6 A;  4FUV A;  5G26 A;  1PRN A;  3PQU A;  3AA0 A;  4AYM C;  4FRT A;  2ZFG A;  1MM5 A;  1GFM A;  3KVD D;  1IZN A;  4JFB A;  2LHF A;  1QJP A;  4O3Z A;  4PUX A;  3T24 A;  5EE2 A;  3AAA A;  4FES A;  4E1T A;  4AYI D;  2QTK A;  1GFQ A;  4O3X B;  5AFU L;  1Q9G A;  4LSH A;  3SZD A;  4KRA A;  1ZHW A;  4LSE A;  2YPV A;  2ODJ A;  3VZU X;  4FSO A;  1IZN B;  1OSM A;  3SYB A;  3HOL A;  4RLC A;  4B61 A;  5ADX K;  2XE1 A;  4O4X A;  4AUI A;  1E54 A;  3LK4 1;  2PRN A;  3SYS A;  2K0L A;  2K4T A;  4GF4 A;  1H6S 1;  4O4U A;  3VZT X;  2XE3 A;  1OPF A;  5ADX L;  2Y7S A;  5T5F A;  3POX A;  5FVN A;  4XNL A;  5AFU K;  3HOE A;  3O0E A;  4FZN A;  2FGR A;  2Y2X A;  2POR A;  4LSF A;  4RJW A;  4F4B A;  3VY9 X;  2F1T A;  3QRA A;  2ZLD A;  3RBH A;  4D65 A;  5DL7 A;  4GCP A;  3AAE B;  3EMN X;  4N59 A;  3AA7 A;  1ZHZ A;  3V8U A;  4FOZ A;  2XE2 A;  2Y0L A;  4O3Y A;  1BT9 A;  3T0S A;  3AA1 B;  1HXT A;  2LFU A;  3VZW X;  4FZM A;  3FYX A;  2XTR A;  3LK2 B;  4O3W A;  1Q9F A;  1BXW A;  4GCQ A;  1ORM A;  2J4U P;  7PRN A;  4AKM A;  2W80 C;  4AFK A;  2KC0 A;  3UAQ A;  3SY9 A;  1THQ A;  2XE5 A;  4LSI A;  4D5U A;  5JDP A;  3SY7 A;  2GE4 A;  3AA6 A;  1GFO A;  3VE2 A;  4GCS A;  3WI5 A;  2YNK A;  3AA7 B;  3AAE A;  2KDY A;  2XTQ A;  4RLB A;  4KR8 A;  4G75 A;  8PRN A;  3AA1 A;  2F1V A;  2Y0H A;  3VY8 X;  1ZHX A;  2W81 C;  3LK2 A;  1G90 A;  5IYU A;  1BH3 A;  3LK4 2;  2XMX A;  1QJ8 A;  2OMF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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