1PHOA

Crystal structures explain functional properties of two e. coli porins
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
330
structure length
330
Chain Sequence
AEIYNKDGNKLDVYGKVKAMHYMSDNASKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGLKYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQNLQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQFDFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNKLNINNDDIVAVGMTYQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures explain functional properties of two E. coli porins.
pubmed doi rcsb
molecule tags Outer membrane protein
source organism Escherichia coli
molecule keywords PHOSPHOPORIN
total genus 77
structure length 330
sequence length 330
ec nomenclature
pdb deposition date 1993-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00267 Porin_1 Gram-negative porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 1phoA00
8PRNA 4FRTA 3WI4A 5DL8A 3POXA 3K19A 3POUA 4LSFA 3VZUX 2Y0LA 4D65A 1HXTA 3T0SA 4FSOA 3T24A 4D64A 1GFOA 3JTYA 4FSPA 4RJWA 2OMFA 5DL5A 3SZDA 1GFNA 4FRXA 4JFBA 2O4VA 1HXUA 3A2SX 4C69X 4LSEA 4D5UA 3SY9A 1BH3A 3SZVA 2XE5A 3EMNX 5PRNA 4RJXA 3NSGA 4BUMX 2Y0KA 1MPFA 4GCSA 3VY8X 1GFPA 3FYXA 3WI5A 3SY7A 4KRAA 1GFQA 2XE3A 1H6S1 2ZFGA 3O0EA 2PRNA 3POQA 2J4UP 5JDPA 4KR8A 4GCPA 6PRNA 2QTKA 1BT9A 4GCQA 3SYBA 2ZLDA 4FT6A 2PORA 5FVNA 1OPFA 1OSMA 1PRNA 2XE1A 1E54A 3HW9A 3HWBA 2XE2A 3UU2A 3VY9X 2FGRA 2ODJA 2FGQX 3VZWX 2Y2XA 4FMSA 4LSIA 4AUIA 2K4TA 2XG6A 4FOZA 2J1NA 4KR4A 7PRNA 3PRNA 2Y0HA 5DL7A 3SYSA 3T20A 1GFMA 3VZTX 1PHOA 3PORA 1HXXA 5DL6A 4LSHA 3UPGA
chains in the Genus database with same CATH superfamily
4C4VA 8PRNA 4FRTA 4O4UA 3WI4A 4RLCA 5DL8A 3POXA 4C00A 5AFUL 4FZNA 3LK2A 3K19A 3POUA 4LSFA 3DA3A 1ZHZA 1IZNB 2Y0LA 3VZUX 1ZHXA 3HOLA 2KXPB 1HXTA 5GTIO 3T0SA 4D65A 4O49A 4B61A 4FSOA 3BRZA 3AAEA 3T24A 1YS5A 4C4VB 1MM4A 1T1LA 1GFOA 2AXTO 3AA0A 4O3WA 2R88A 4D64A 3LK2B 3JTYA 3PGRA 2N2LA 2W81C 3PQSA 4FSPA 4PUXA 4RJWA 2OMFA 3HOEA 4N75A 1Q9FA 2KC0A 5DL5A 3SZDA 1GFNA 3BRYA 4FRXA 4CTDA 4JFBA 3A0HO 4FESA 5B66O 4AFKA 2O4VA 1QJ8A 3NJTA 1HXUA 4FZMA 1IZNA 3A2SX 4C69X 1BXWA 4LSEA 1ZHTA 4U9CA 4D5UA 3SY9A 1S5LO 4PR7A 3LK42 5TISO 1P4TA 4QQ1A 1BH3A 2XMXA 3RBHA 2LHFA 5E79O 3SZVA 5GTHO 2XE5A 3EMNX 2YNKA 2R8AA 2F1TA 3VE1A 5PRNA 2M06A 3AA1A 1QJPA 4RJXA 2GE4A 4AKRA 2R4LA 3NSGA 4FUVA 4BUMX 1G90A 4O3XB 2Y0KA 4K3CA 3DWNA 3QRCA 3DA4A 1MM5A 1MPFA 3C5OA 3AA7B 3QRAA 3A0BO 4O3ZA 4GCSA 3LK3B 1THQA 5ADXL 3AA6A 4RL9A 2LFUA 5D5DA 3VY8X 4PJ0O 4AYEC 3AA1B 4AKRB 4AYDC 4G76A 4IL6O 3WU2O 2W80C 1GFPA 3FYXA 3WI5A 3SY7A 2K0LA 5G3AA 4KRAA 4N58A 1GFQA 5H2FO 2XE3A 4AYMC 2IWWA 1H6S1 2X9KA 2ZFGA 2Y7SA 5GV0A 3O0EA 2PRNA 3TZGA 3AA6B 5G39A 1ORMA 5G38A 2YPVA 2ERVA 2JMMA 4G75A 3AA7A 3PGUA 3PGSA 2F1VA 3POQA 2R4PA 3V8UA 3LK3A 2WJRA 3DWOX 4UB8O 2KZ7A 5JDPA 4AZLA 2WVPA 2J4UP 4KR8A 3BS0A 2JQYA 2X27X 4GCPA 4AYID 2QTKA 6PRNA 4Z3TA 1BT9A 4O3YA 5EE2A 4JCHA 1T16A 2XTRA 4GCQA 4UB6O 3SYBA 2ZLDA 4FT6A 2R4OA 4GHBA 2KDYA 2MHLA 2PORA 5G26A 4RLBA 3VE2A 5FVNA 4N74A 4AKMA 1OPFA 1OSMA 2KZ7B 1PRNA 5B5EO 2XE1A 2IWVA 3LK41 5T5FA 1E54A 3PQUA 5AFUK 3HW9A 4E1SA 1Q9GA 3HWBA 2N2MA 2XE2A 4E1TA 3JCUO 3UU2A 3PF1A 3VY9X 2FGRA 3G7GA 2ODJA 2FGQX 3VZWX 2F1CX 2M07A 2Y2XA 3KVDD 1ZHWA 3KZIO 4FMSA 4K3BA 4LSIA 4XNKA 5KAFO 4AUIA 2K4TA 2MNHA 2XG6A 4FOZA 2J1NA 4FZLA 4N59A 4O4XA 5ADXK 4KR4A 3GP6A 5KAIO 4GF4A 7PRNA 3PRNA 2Y0HA 3DZMA 3AAAA 5DL7A 3SYSA 3T20A 1GFMA 2WJQA 4AYNA 2R89A 2XTQA 1QJ9A 3VZTX 3UPGA 3AAEB 5IYUA 3UAQA 1PHOA 3PORA 1HXXA 1ZHYA 3AA0B 4FQEA 4XNLA 2KXPA 4F4BA 2R4NA 5DL6A 4LSHA 3AAAB
chains in the Genus database with same CATH topology
8PRNA 4FRTA 4O4UA 3WI4A 4RLCA 5DL8A 3POXA 5AFUL 4FZNA 3LK2A 3K19A 3POUA 4LSFA 3DA3A 1ZHZA 1IZNB 2Y0LA 3VZUX 1ZHXA 3HOLA 2KXPB 1HXTA 4D65A 3T0SA 4O49A 4B61A 4FSOA 3AAEA 3T24A 1YS5A 1MM4A 4D64A 1GFOA 4O3WA 3AA0A 3LK2B 3JTYA 3PQSA 2N2LA 2W81C 4FSPA 4PUXA 4RJWA 5ADXL 2OMFA 3HOEA 1Q9FA 2KC0A 5DL5A 3SZDA 1GFNA 4FRXA 4JFBA 4FESA 4AFKA 2O4VA 1QJ8A 1HXUA 4FZMA 1IZNA 3A2SX 4C69X 1BXWA 4LSEA 1ZHTA 4U9CA 4D5UA 3SY9A 3LK42 1P4TA 4QQ1A 1BH3A 2XMXA 3RBHA 2LHFA 3SZVA 2XE5A 3EMNX 2YNKA 3VE1A 2F1TA 5PRNA 2M06A 3AA1A 1QJPA 4RJXA 2GE4A 4AKRA 3NSGA 4FUVA 4BUMX 1G90A 4O3XB 2Y0KA 3QRCA 3DA4A 1MM5A 1MPFA 3C5OA 3AA7B 3QRAA 4O3ZA 4GCSA 3LK3B 1THQA 3AA6A 4RL9A 2LFUA 5D5DA 3VY8X 4AYEC 3AA1B 4AKRB 4AYDC 4G76A 2W80C 1GFPA 3FYXA 3WI5A 3SY7A 2K0LA 4KRAA 4N58A 1GFQA 2XE3A 4AYMC 1H6S1 2ZFGA 2Y7SA 5GV0A 3O0EA 2PRNA 3TZGA 3AA6B 1ORMA 2YPVA 2ERVA 2JMMA 4G75A 3AA7A 3POQA 2F1VA 3V8UA 3LK3A 2J4UP 2KZ7A 5JDPA 4AZLA 4KR8A 4AYID 2X27X 4GCPA 6PRNA 2QTKA 4Z3TA 1BT9A 4O3YA 5EE2A 4JCHA 3UPGA 2XTRA 4GCQA 3SYBA 2ZLDA 4FT6A 5G26A 4GHBA 2KDYA 2MHLA 2PORA 4RLBA 3VE2A 5FVNA 4AKMA 1OPFA 1OSMA 2KZ7B 1PRNA 2XE1A 3LK41 5T5FA 1E54A 3PQUA 5AFUK 3HW9A 4E1SA 1Q9GA 3HWBA 2XE2A 2N2MA 4E1TA 3UU2A 3VY9X 2FGRA 3G7GA 2ODJA 2FGQX 3VZWX 2M07A 2Y2XA 3KVDD 1ZHWA 4FMSA 4LSIA 4XNKA 4AUIA 2K4TA 2MNHA 2XG6A 4FOZA 2J1NA 4FZLA 4N59A 4O4XA 5ADXK 4KR4A 3GP6A 4GF4A 7PRNA 3PRNA 2Y0HA 5DL7A 3AAAA 3SYSA 3T20A 1GFMA 4AYNA 2XTQA 3VZTX 1QJ9A 3AAEB 5IYUA 3UAQA 1PHOA 3PORA 1HXXA 1ZHYA 3AA0B 4XNLA 2KXPA 4F4BA 5DL6A 4LSHA 3AAAB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 8PRN A;  4FRT A;  3WI4 A;  5DL8 A;  3POX A;  3K19 A;  3POU A;  4LSF A;  3VZU X;  2Y0L A;  4D65 A;  1HXT A;  3T0S A;  4FSO A;  3T24 A;  4D64 A;  1GFO A;  3JTY A;  4FSP A;  4RJW A;  2OMF A;  5DL5 A;  3SZD A;  1GFN A;  4FRX A;  4JFB A;  2O4V A;  1HXU A;  3A2S X;  4C69 X;  4LSE A;  4D5U A;  3SY9 A;  1BH3 A;  3SZV A;  2XE5 A;  3EMN X;  5PRN A;  4RJX A;  3NSG A;  4BUM X;  2Y0K A;  1MPF A;  4GCS A;  3VY8 X;  1GFP A;  3FYX A;  3WI5 A;  3SY7 A;  4KRA A;  1GFQ A;  2XE3 A;  1H6S 1;  2ZFG A;  3O0E A;  2PRN A;  3POQ A;  2J4U P;  5JDP A;  4KR8 A;  4GCP A;  6PRN A;  2QTK A;  1BT9 A;  4GCQ A;  3SYB A;  2ZLD A;  4FT6 A;  2POR A;  5FVN A;  1OPF A;  1OSM A;  1PRN A;  2XE1 A;  1E54 A;  3HW9 A;  3HWB A;  2XE2 A;  3UU2 A;  3VY9 X;  2FGR A;  2ODJ A;  2FGQ X;  3VZW X;  2Y2X A;  4FMS A;  4LSI A;  4AUI A;  2K4T A;  2XG6 A;  4FOZ A;  2J1N A;  4KR4 A;  7PRN A;  3PRN A;  2Y0H A;  5DL7 A;  3SYS A;  3T20 A;  1GFM A;  3VZT X;  1PHO A;  3POR A;  1HXX A;  5DL6 A;  4LSH A;  3UPG A; 
#chains in the Genus database with same CATH topology
 4C4V A;  8PRN A;  4FRT A;  4O4U A;  3WI4 A;  4RLC A;  5DL8 A;  3POX A;  4C00 A;  5AFU L;  4FZN A;  3LK2 A;  3K19 A;  3POU A;  4LSF A;  3DA3 A;  1ZHZ A;  1IZN B;  2Y0L A;  3VZU X;  1ZHX A;  3HOL A;  2KXP B;  1HXT A;  5GTI O;  3T0S A;  4D65 A;  4O49 A;  4B61 A;  4FSO A;  3BRZ A;  3AAE A;  3T24 A;  1YS5 A;  4C4V B;  1MM4 A;  1T1L A;  1GFO A;  2AXT O;  3AA0 A;  4O3W A;  2R88 A;  4D64 A;  3LK2 B;  3JTY A;  3PGR A;  2N2L A;  2W81 C;  3PQS A;  4FSP A;  4PUX A;  4RJW A;  2OMF A;  3HOE A;  4N75 A;  1Q9F A;  2KC0 A;  5DL5 A;  3SZD A;  1GFN A;  3BRY A;  4FRX A;  4CTD A;  4JFB A;  3A0H O;  4FES A;  5B66 O;  4AFK A;  2O4V A;  1QJ8 A;  3NJT A;  1HXU A;  4FZM A;  1IZN A;  3A2S X;  4C69 X;  1BXW A;  4LSE A;  1ZHT A;  4U9C A;  4D5U A;  3SY9 A;  1S5L O;  4PR7 A;  3LK4 2;  5TIS O;  1P4T A;  4QQ1 A;  1BH3 A;  2XMX A;  3RBH A;  2LHF A;  5E79 O;  3SZV A;  5GTH O;  2XE5 A;  3EMN X;  2YNK A;  2R8A A;  2F1T A;  3VE1 A;  5PRN A;  2M06 A;  3AA1 A;  1QJP A;  4RJX A;  2GE4 A;  4AKR A;  2R4L A;  3NSG A;  4FUV A;  4BUM X;  1G90 A;  4O3X B;  2Y0K A;  4K3C A;  3DWN A;  3QRC A;  3DA4 A;  1MM5 A;  1MPF A;  3C5O A;  3AA7 B;  3QRA A;  3A0B O;  4O3Z A;  4GCS A;  3LK3 B;  1THQ A;  5ADX L;  3AA6 A;  4RL9 A;  2LFU A;  5D5D A;  3VY8 X;  4PJ0 O;  4AYE C;  3AA1 B;  4AKR B;  4AYD C;  4G76 A;  4IL6 O;  3WU2 O;  2W80 C;  1GFP A;  3FYX A;  3WI5 A;  3SY7 A;  2K0L A;  5G3A A;  4KRA A;  4N58 A;  1GFQ A;  5H2F O;  2XE3 A;  4AYM C;  2IWW A;  1H6S 1;  2X9K A;  2ZFG A;  2Y7S A;  5GV0 A;  3O0E A;  2PRN A;  3TZG A;  3AA6 B;  5G39 A;  1ORM A;  5G38 A;  2YPV A;  2ERV A;  2JMM A;  4G75 A;  3AA7 A;  3PGU A;  3PGS A;  2F1V A;  3POQ A;  2R4P A;  3V8U A;  3LK3 A;  2WJR A;  3DWO X;  4UB8 O;  2KZ7 A;  5JDP A;  4AZL A;  2WVP A;  2J4U P;  4KR8 A;  3BS0 A;  2JQY A;  2X27 X;  4GCP A;  4AYI D;  2QTK A;  6PRN A;  4Z3T A;  1BT9 A;  4O3Y A;  5EE2 A;  4JCH A;  1T16 A;  2XTR A;  4GCQ A;  4UB6 O;  3SYB A;  2ZLD A;  4FT6 A;  2R4O A;  4GHB A;  2KDY A;  2MHL A;  2POR A;  5G26 A;  4RLB A;  3VE2 A;  5FVN A;  4N74 A;  4AKM A;  1OPF A;  1OSM A;  2KZ7 B;  1PRN A;  5B5E O;  2XE1 A;  2IWV A;  3LK4 1;  5T5F A;  1E54 A;  3PQU A;  5AFU K;  3HW9 A;  4E1S A;  1Q9G A;  3HWB A;  2N2M A;  2XE2 A;  4E1T A;  3JCU O;  3UU2 A;  3PF1 A;  3VY9 X;  2FGR A;  3G7G A;  2ODJ A;  2FGQ X;  3VZW X;  2F1C X;  2M07 A;  2Y2X A;  3KVD D;  1ZHW A;  3KZI O;  4FMS A;  4K3B A;  4LSI A;  4XNK A;  5KAF O;  4AUI A;  2K4T A;  2MNH A;  2XG6 A;  4FOZ A;  2J1N A;  4FZL A;  4N59 A;  4O4X A;  5ADX K;  4KR4 A;  3GP6 A;  5KAI O;  4GF4 A;  7PRN A;  3PRN A;  2Y0H A;  3DZM A;  3AAA A;  5DL7 A;  3SYS A;  3T20 A;  1GFM A;  2WJQ A;  4AYN A;  2R89 A;  2XTQ A;  1QJ9 A;  3VZT X;  3UPG A;  3AAE B;  5IYU A;  3UAQ A;  1PHO A;  3POR A;  1HXX A;  1ZHY A;  3AA0 B;  4FQE A;  4XNL A;  2KXP A;  4F4B A;  2R4N A;  5DL6 A;  4LSH A;  3AAA B; 
#chains in the Genus database with same CATH homology
 8PRN A;  4FRT A;  4O4U A;  3WI4 A;  4RLC A;  5DL8 A;  3POX A;  5AFU L;  4FZN A;  3LK2 A;  3K19 A;  3POU A;  4LSF A;  3DA3 A;  1ZHZ A;  1IZN B;  2Y0L A;  3VZU X;  1ZHX A;  3HOL A;  2KXP B;  1HXT A;  4D65 A;  3T0S A;  4O49 A;  4B61 A;  4FSO A;  3AAE A;  3T24 A;  1YS5 A;  1MM4 A;  4D64 A;  1GFO A;  4O3W A;  3AA0 A;  3LK2 B;  3JTY A;  3PQS A;  2N2L A;  2W81 C;  4FSP A;  4PUX A;  4RJW A;  5ADX L;  2OMF A;  3HOE A;  1Q9F A;  2KC0 A;  5DL5 A;  3SZD A;  1GFN A;  4FRX A;  4JFB A;  4FES A;  4AFK A;  2O4V A;  1QJ8 A;  1HXU A;  4FZM A;  1IZN A;  3A2S X;  4C69 X;  1BXW A;  4LSE A;  1ZHT A;  4U9C A;  4D5U A;  3SY9 A;  3LK4 2;  1P4T A;  4QQ1 A;  1BH3 A;  2XMX A;  3RBH A;  2LHF A;  3SZV A;  2XE5 A;  3EMN X;  2YNK A;  3VE1 A;  2F1T A;  5PRN A;  2M06 A;  3AA1 A;  1QJP A;  4RJX A;  2GE4 A;  4AKR A;  3NSG A;  4FUV A;  4BUM X;  1G90 A;  4O3X B;  2Y0K A;  3QRC A;  3DA4 A;  1MM5 A;  1MPF A;  3C5O A;  3AA7 B;  3QRA A;  4O3Z A;  4GCS A;  3LK3 B;  1THQ A;  3AA6 A;  4RL9 A;  2LFU A;  5D5D A;  3VY8 X;  4AYE C;  3AA1 B;  4AKR B;  4AYD C;  4G76 A;  2W80 C;  1GFP A;  3FYX A;  3WI5 A;  3SY7 A;  2K0L A;  4KRA A;  4N58 A;  1GFQ A;  2XE3 A;  4AYM C;  1H6S 1;  2ZFG A;  2Y7S A;  5GV0 A;  3O0E A;  2PRN A;  3TZG A;  3AA6 B;  1ORM A;  2YPV A;  2ERV A;  2JMM A;  4G75 A;  3AA7 A;  3POQ A;  2F1V A;  3V8U A;  3LK3 A;  2J4U P;  2KZ7 A;  5JDP A;  4AZL A;  4KR8 A;  4AYI D;  2X27 X;  4GCP A;  6PRN A;  2QTK A;  4Z3T A;  1BT9 A;  4O3Y A;  5EE2 A;  4JCH A;  3UPG A;  2XTR A;  4GCQ A;  3SYB A;  2ZLD A;  4FT6 A;  5G26 A;  4GHB A;  2KDY A;  2MHL A;  2POR A;  4RLB A;  3VE2 A;  5FVN A;  4AKM A;  1OPF A;  1OSM A;  2KZ7 B;  1PRN A;  2XE1 A;  3LK4 1;  5T5F A;  1E54 A;  3PQU A;  5AFU K;  3HW9 A;  4E1S A;  1Q9G A;  3HWB A;  2XE2 A;  2N2M A;  4E1T A;  3UU2 A;  3VY9 X;  2FGR A;  3G7G A;  2ODJ A;  2FGQ X;  3VZW X;  2M07 A;  2Y2X A;  3KVD D;  1ZHW A;  4FMS A;  4LSI A;  4XNK A;  4AUI A;  2K4T A;  2MNH A;  2XG6 A;  4FOZ A;  2J1N A;  4FZL A;  4N59 A;  4O4X A;  5ADX K;  4KR4 A;  3GP6 A;  4GF4 A;  7PRN A;  3PRN A;  2Y0H A;  5DL7 A;  3AAA A;  3SYS A;  3T20 A;  1GFM A;  4AYN A;  2XTQ A;  3VZT X;  1QJ9 A;  3AAE B;  5IYU A;  3UAQ A;  1PHO A;  3POR A;  1HXX A;  1ZHY A;  3AA0 B;  4XNL A;  2KXP A;  4F4B A;  5DL6 A;  4LSH A;  3AAA B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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