2K4TA

Solution structure of human vdac-1 in ldao micelles
Total Genus 43

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
285
structure length
285
Chain Sequence
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQALE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
Updating...
connected with : NaN
molecule tags Membrane protein,apoptosis
source organism Homo sapiens
publication title Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.
pubmed doi rcsb
molecule keywords Voltage-dependent anion-selective channel protein 1
total genus 43
structure length 285
sequence length 285
ec nomenclature
pdb deposition date 2008-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 2k4tA00
8PRNA 1OPFA 2Y0LA 2K4TA 1HXXA 2Y0KA 5FVNA 4FT6A 3HW9A 4GCPA 3K19A 1BT9A 2O4VA 2XE1A 2FGRA 2XE3A 4D64A 4C69X 6PRNA 3POQA 2XE5A 2Y2XA 3VZWX 3A2SX 1BH3A 3VZTX 4FSOA 4GCQA 3T20A 2ZFGA 1H6S1 2ZLDA 4JFBA 3SZDA 3VY8X 4KR8A 3VZUX 4LSIA 3SY9A 4RJWA 4AUIA 3FYXA 1MPFA 3UU2A 5JDPA 3EMNX 1OSMA 3HWBA 4FRXA 1HXUA 4LSHA 2FGQX 4FMSA 4FRTA 2XE2A 3SYBA 3PRNA 3VY9X 3O0EA 3SZVA 3SYSA 4RJXA 3SY7A 2QTKA 1E54A 4LSFA 4KR4A 5DL5A 1GFQA 1GFOA 4GCSA 7PRNA 3NSGA 5DL8A 4FSPA 4D65A 3POUA 2OMFA 3PORA 2PRNA 2PORA 5DL7A 2J4UP 4KRAA 1GFNA 4FOZA 3UPGA 1PRNA 4D5UA 1GFMA 1GFPA 3WI5A 3POXA 3T0SA 1PHOA 4LSEA 2ODJA 2XG6A 3JTYA 5PRNA 3WI4A 2J1NA 2Y0HA 5DL6A 3T24A 4BUMX 1HXTA
chains in the Genus database with same CATH superfamily
4G75A 3AA7A 1P4TA 8PRNA 4PUXA 1OPFA 2Y0LA 4O4XA 2K4TA 4FESA 1HXXA 2IWWA 2Y0KA 1G90A 4C4VB 3BRZA 2LFUA 3LK3B 4FZNA 5G26A 3DA3A 5FVNA 4FT6A 5B5EO 3HW9A 4CTDA 2KZ7A 3PGRA 4FQEA 2XMXA 4GCPA 4N74A 3BS0A 2ERVA 3K19A 3PGUA 2F1TA 1QJ9A 3VE2A 2M07A 4C4VA 2R89A 3HOLA 1BT9A 4C00A 1QJ8A 2KZ7B 2N2LA 5G3AA 2O4VA 1ZHZA 2XE1A 2FGRA 2XTRA 4E1TA 2XE3A 4D64A 4C69X 1Q9GA 6PRNA 5T5FA 3VE1A 1IZNB 3LK3A 2XE5A 2W80C 3POQA 3PQUA 3AA1B 4PJ0O 4XNKA 5GTHO 2Y2XA 2W81C 1THQA 3PQSA 3VZWX 3A2SX 1BH3A 4GF4A 4K3CA 5KAFO 3VZTX 4FSOA 4GCQA 3T20A 2F1VA 4AZLA 2LHFA 2WJRA 5E79O 2X27X 2ZFGA 1H6S1 2ZLDA 4RL9A 3JCUO 2GE4A 4JFBA 3RBHA 4AKMA 4O4UA 2XTQA 3SZDA 4FZLA 2K0LA 4O3WA 2F1CX 3VY8X 4KR8A 3VZUX 4F4BA 4LSIA 2R4PA 3SY9A 4RJWA 5GTIO 1IZNA 4AUIA 3FYXA 4IL6O 5G39A 1MPFA 3AA1A 3UU2A 5KAIO 5JDPA 3A0BO 3V8UA 4RLCA 4RLBA 3EMNX 1OSMA 3HWBA 4UB6O 4FRXA 3GP6A 4E1SA 2X9KA 1HXUA 4B61A 4LSHA 3PGSA 3C5OA 3AA0B 4UB8O 2FGQX 2MHLA 4FMSA 1ZHXA 2XE2A 4FRTA 3PRNA 4FUVA 3SYBA 5TISO 3VY9X 2KXPB 3O0EA 1ZHWA 2YNKA 2YPVA 3DA4A 1S5LO 3A0HO 2N2MA 3QRAA 1MM4A 3AAAB 3SZVA 3HOEA 2M06A 3AAEB 3SYSA 4Z3TA 4N58A 4AKRB 5D5DA 1BXWA 3AA6B 3WU2O 2R4LA 4RJXA 4G76A 5H2FO 3SY7A 2QTKA 3NJTA 4AYMC 1E54A 4LSFA 1ORMA 4KR4A 5EE2A 3UAQA 5ADXK 5GV0A 5DL5A 1QJPA 3AA0A 1GFQA 2IWVA 4O49A 4AYNA 1ZHYA 1GFOA 5IYUA 5G38A 3DWOX 4GCSA 1Q9FA 2KXPA 2R88A 3LK41 4O3ZA 7PRNA 3NSGA 2MNHA 4GHBA 1YS5A 4PR7A 1T1LA 3TZGA 3AAAA 2R4NA 2KC0A 3KZIO 3PF1A 3AAEA 5DL8A 4FSPA 4AKRA 4D65A 1T16A 4FZMA 4JCHA 4N59A 2R4OA 3AA6A 3LK2B 2WVPA 3POUA 2OMFA 4AFKA 3PORA 3DWNA 2PRNA 1MM5A 3DZMA 4O3YA 3KVDD 2PORA 3AA7B 2JQYA 5DL7A 5AFUL 4KRAA 2J4UP 1GFNA 4FOZA 3G7GA 4QQ1A 4U9CA 1PRNA 4N75A 4D5UA 3UPGA 1GFMA 1GFPA 3WI5A 3LK42 4AYEC 3POXA 5ADXL 2WJQA 3T0SA 1PHOA 4AYDC 4LSEA 2JMMA 2AXTO 2ODJA 3QRCA 2XG6A 3JTYA 4XNLA 3LK2A 5PRNA 3WI4A 5AFUK 2J1NA 4O3XB 2Y0HA 3BRYA 2Y7SA 4K3BA 2KDYA 5DL6A 3T24A 2R8AA 4AYID 4BUMX 1ZHTA 5B66O 1HXTA
chains in the Genus database with same CATH topology
4G75A 3AA7A 1P4TA 8PRNA 4PUXA 1OPFA 2Y0LA 4O4XA 2K4TA 4FESA 1HXXA 2Y0KA 1G90A 5G26A 2LFUA 3LK3B 4FZNA 3DA3A 5FVNA 4FT6A 3HW9A 2KZ7A 4GCPA 2XMXA 2ERVA 3K19A 3VE2A 2F1TA 1QJ9A 2M07A 3HOLA 1BT9A 1QJ8A 2KZ7B 2N2LA 2O4VA 1ZHZA 2XE1A 2FGRA 2XTRA 4E1TA 2XE3A 4D64A 4C69X 1Q9GA 6PRNA 5T5FA 3VE1A 1IZNB 3LK3A 2XE5A 2W80C 3POQA 3PQUA 3AA1B 4XNKA 2Y2XA 2W81C 1THQA 3PQSA 3VZWX 3A2SX 1BH3A 4GF4A 3VZTX 4FSOA 4GCQA 3T20A 2F1VA 4AZLA 2LHFA 2X27X 2ZFGA 1H6S1 2ZLDA 4RL9A 2GE4A 4JFBA 3RBHA 4AKMA 4O4UA 2XTQA 3SZDA 4FZLA 2K0LA 4O3WA 3VY8X 4KR8A 3VZUX 4F4BA 4LSIA 3SY9A 4RJWA 1IZNA 4AUIA 3FYXA 1MPFA 3AA1A 3UU2A 5JDPA 3V8UA 4RLCA 4RLBA 3EMNX 1OSMA 3HWBA 4FRXA 3GP6A 4E1SA 1HXUA 4B61A 4LSHA 3C5OA 3AA0B 2FGQX 2MHLA 4FMSA 1ZHXA 2XE2A 4FRTA 3PRNA 4FUVA 3SYBA 3VY9X 2KXPB 3O0EA 1ZHWA 2YNKA 2YPVA 3DA4A 3SZVA 2N2MA 3QRAA 1MM4A 3AAAB 3HOEA 2M06A 3AAEB 3SYSA 4Z3TA 4N58A 4AKRB 5D5DA 1BXWA 3AA6B 4RJXA 4G76A 3SY7A 2QTKA 4AYMC 1E54A 4LSFA 1ORMA 4KR4A 5EE2A 3UAQA 5ADXK 5GV0A 5DL5A 1QJPA 3AA0A 1GFQA 4O49A 4AYNA 1ZHYA 1GFOA 5IYUA 4GCSA 1Q9FA 2KXPA 4O3ZA 3LK41 7PRNA 3NSGA 2MNHA 4GHBA 1YS5A 3TZGA 3AAAA 2KC0A 3AAEA 5DL8A 4FSPA 4AKRA 4D65A 4JCHA 4FZMA 4N59A 3AA6A 3LK2B 3POUA 2OMFA 4AFKA 3PORA 2PRNA 1MM5A 4O3YA 3KVDD 2PORA 3AA7B 5DL7A 5AFUL 2J4UP 4KRAA 1GFNA 4FOZA 3G7GA 4QQ1A 4U9CA 1PRNA 4D5UA 3UPGA 1GFMA 1GFPA 3WI5A 3LK42 4AYEC 3POXA 5ADXL 3T0SA 1PHOA 4AYDC 4LSEA 2JMMA 2ODJA 3QRCA 2XG6A 3JTYA 4XNLA 3LK2A 5PRNA 3WI4A 5AFUK 2J1NA 4O3XB 2Y0HA 5DL6A 2Y7SA 3T24A 2KDYA 4AYID 4BUMX 1ZHTA 1HXTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 8PRN A;  1OPF A;  2Y0L A;  2K4T A;  1HXX A;  2Y0K A;  5FVN A;  4FT6 A;  3HW9 A;  4GCP A;  3K19 A;  1BT9 A;  2O4V A;  2XE1 A;  2FGR A;  2XE3 A;  4D64 A;  4C69 X;  6PRN A;  3POQ A;  2XE5 A;  2Y2X A;  3VZW X;  3A2S X;  1BH3 A;  3VZT X;  4FSO A;  4GCQ A;  3T20 A;  2ZFG A;  1H6S 1;  2ZLD A;  4JFB A;  3SZD A;  3VY8 X;  4KR8 A;  3VZU X;  4LSI A;  3SY9 A;  4RJW A;  4AUI A;  3FYX A;  1MPF A;  3UU2 A;  5JDP A;  3EMN X;  1OSM A;  3HWB A;  4FRX A;  1HXU A;  4LSH A;  2FGQ X;  4FMS A;  4FRT A;  2XE2 A;  3SYB A;  3PRN A;  3VY9 X;  3O0E A;  3SZV A;  3SYS A;  4RJX A;  3SY7 A;  2QTK A;  1E54 A;  4LSF A;  4KR4 A;  5DL5 A;  1GFQ A;  1GFO A;  4GCS A;  7PRN A;  3NSG A;  5DL8 A;  4FSP A;  4D65 A;  3POU A;  2OMF A;  3POR A;  2PRN A;  2POR A;  5DL7 A;  2J4U P;  4KRA A;  1GFN A;  4FOZ A;  3UPG A;  1PRN A;  4D5U A;  1GFM A;  1GFP A;  3WI5 A;  3POX A;  3T0S A;  1PHO A;  4LSE A;  2ODJ A;  2XG6 A;  3JTY A;  5PRN A;  3WI4 A;  2J1N A;  2Y0H A;  5DL6 A;  3T24 A;  4BUM X;  1HXT A; 
#chains in the Genus database with same CATH topology
 4G75 A;  3AA7 A;  1P4T A;  8PRN A;  4PUX A;  1OPF A;  2Y0L A;  4O4X A;  2K4T A;  4FES A;  1HXX A;  2IWW A;  2Y0K A;  1G90 A;  4C4V B;  3BRZ A;  2LFU A;  3LK3 B;  4FZN A;  5G26 A;  3DA3 A;  5FVN A;  4FT6 A;  5B5E O;  3HW9 A;  4CTD A;  2KZ7 A;  3PGR A;  4FQE A;  2XMX A;  4GCP A;  4N74 A;  3BS0 A;  2ERV A;  3K19 A;  3PGU A;  2F1T A;  1QJ9 A;  3VE2 A;  2M07 A;  4C4V A;  2R89 A;  3HOL A;  1BT9 A;  4C00 A;  1QJ8 A;  2KZ7 B;  2N2L A;  5G3A A;  2O4V A;  1ZHZ A;  2XE1 A;  2FGR A;  2XTR A;  4E1T A;  2XE3 A;  4D64 A;  4C69 X;  1Q9G A;  6PRN A;  5T5F A;  3VE1 A;  1IZN B;  3LK3 A;  2XE5 A;  2W80 C;  3POQ A;  3PQU A;  3AA1 B;  4PJ0 O;  4XNK A;  5GTH O;  2Y2X A;  2W81 C;  1THQ A;  3PQS A;  3VZW X;  3A2S X;  1BH3 A;  4GF4 A;  4K3C A;  5KAF O;  3VZT X;  4FSO A;  4GCQ A;  3T20 A;  2F1V A;  4AZL A;  2LHF A;  2WJR A;  5E79 O;  2X27 X;  2ZFG A;  1H6S 1;  2ZLD A;  4RL9 A;  3JCU O;  2GE4 A;  4JFB A;  3RBH A;  4AKM A;  4O4U A;  2XTQ A;  3SZD A;  4FZL A;  2K0L A;  4O3W A;  2F1C X;  3VY8 X;  4KR8 A;  3VZU X;  4F4B A;  4LSI A;  2R4P A;  3SY9 A;  4RJW A;  5GTI O;  1IZN A;  4AUI A;  3FYX A;  4IL6 O;  5G39 A;  1MPF A;  3AA1 A;  3UU2 A;  5KAI O;  5JDP A;  3A0B O;  3V8U A;  4RLC A;  4RLB A;  3EMN X;  1OSM A;  3HWB A;  4UB6 O;  4FRX A;  3GP6 A;  4E1S A;  2X9K A;  1HXU A;  4B61 A;  4LSH A;  3PGS A;  3C5O A;  3AA0 B;  4UB8 O;  2FGQ X;  2MHL A;  4FMS A;  1ZHX A;  2XE2 A;  4FRT A;  3PRN A;  4FUV A;  3SYB A;  5TIS O;  3VY9 X;  2KXP B;  3O0E A;  1ZHW A;  2YNK A;  2YPV A;  3DA4 A;  1S5L O;  3A0H O;  2N2M A;  3QRA A;  1MM4 A;  3AAA B;  3SZV A;  3HOE A;  2M06 A;  3AAE B;  3SYS A;  4Z3T A;  4N58 A;  4AKR B;  5D5D A;  1BXW A;  3AA6 B;  3WU2 O;  2R4L A;  4RJX A;  4G76 A;  5H2F O;  3SY7 A;  2QTK A;  3NJT A;  4AYM C;  1E54 A;  4LSF A;  1ORM A;  4KR4 A;  5EE2 A;  3UAQ A;  5ADX K;  5GV0 A;  5DL5 A;  1QJP A;  3AA0 A;  1GFQ A;  2IWV A;  4O49 A;  4AYN A;  1ZHY A;  1GFO A;  5IYU A;  5G38 A;  3DWO X;  4GCS A;  1Q9F A;  2KXP A;  2R88 A;  3LK4 1;  4O3Z A;  7PRN A;  3NSG A;  2MNH A;  4GHB A;  1YS5 A;  4PR7 A;  1T1L A;  3TZG A;  3AAA A;  2R4N A;  2KC0 A;  3KZI O;  3PF1 A;  3AAE A;  5DL8 A;  4FSP A;  4AKR A;  4D65 A;  1T16 A;  4FZM A;  4JCH A;  4N59 A;  2R4O A;  3AA6 A;  3LK2 B;  2WVP A;  3POU A;  2OMF A;  4AFK A;  3POR A;  3DWN A;  2PRN A;  1MM5 A;  3DZM A;  4O3Y A;  3KVD D;  2POR A;  3AA7 B;  2JQY A;  5DL7 A;  5AFU L;  4KRA A;  2J4U P;  1GFN A;  4FOZ A;  3G7G A;  4QQ1 A;  4U9C A;  1PRN A;  4N75 A;  4D5U A;  3UPG A;  1GFM A;  1GFP A;  3WI5 A;  3LK4 2;  4AYE C;  3POX A;  5ADX L;  2WJQ A;  3T0S A;  1PHO A;  4AYD C;  4LSE A;  2JMM A;  2AXT O;  2ODJ A;  3QRC A;  2XG6 A;  3JTY A;  4XNL A;  3LK2 A;  5PRN A;  3WI4 A;  5AFU K;  2J1N A;  4O3X B;  2Y0H A;  3BRY A;  2Y7S A;  4K3B A;  2KDY A;  5DL6 A;  3T24 A;  2R8A A;  4AYI D;  4BUM X;  1ZHT A;  5B66 O;  1HXT A; 
#chains in the Genus database with same CATH homology
 4G75 A;  3AA7 A;  1P4T A;  8PRN A;  4PUX A;  1OPF A;  2Y0L A;  4O4X A;  2K4T A;  4FES A;  1HXX A;  2Y0K A;  1G90 A;  5G26 A;  2LFU A;  3LK3 B;  4FZN A;  3DA3 A;  5FVN A;  4FT6 A;  3HW9 A;  2KZ7 A;  4GCP A;  2XMX A;  2ERV A;  3K19 A;  3VE2 A;  2F1T A;  1QJ9 A;  2M07 A;  3HOL A;  1BT9 A;  1QJ8 A;  2KZ7 B;  2N2L A;  2O4V A;  1ZHZ A;  2XE1 A;  2FGR A;  2XTR A;  4E1T A;  2XE3 A;  4D64 A;  4C69 X;  1Q9G A;  6PRN A;  5T5F A;  3VE1 A;  1IZN B;  3LK3 A;  2XE5 A;  2W80 C;  3POQ A;  3PQU A;  3AA1 B;  4XNK A;  2Y2X A;  2W81 C;  1THQ A;  3PQS A;  3VZW X;  3A2S X;  1BH3 A;  4GF4 A;  3VZT X;  4FSO A;  4GCQ A;  3T20 A;  2F1V A;  4AZL A;  2LHF A;  2X27 X;  2ZFG A;  1H6S 1;  2ZLD A;  4RL9 A;  2GE4 A;  4JFB A;  3RBH A;  4AKM A;  4O4U A;  2XTQ A;  3SZD A;  4FZL A;  2K0L A;  4O3W A;  3VY8 X;  4KR8 A;  3VZU X;  4F4B A;  4LSI A;  3SY9 A;  4RJW A;  1IZN A;  4AUI A;  3FYX A;  1MPF A;  3AA1 A;  3UU2 A;  5JDP A;  3V8U A;  4RLC A;  4RLB A;  3EMN X;  1OSM A;  3HWB A;  4FRX A;  3GP6 A;  4E1S A;  1HXU A;  4B61 A;  4LSH A;  3C5O A;  3AA0 B;  2FGQ X;  2MHL A;  4FMS A;  1ZHX A;  2XE2 A;  4FRT A;  3PRN A;  4FUV A;  3SYB A;  3VY9 X;  2KXP B;  3O0E A;  1ZHW A;  2YNK A;  2YPV A;  3DA4 A;  3SZV A;  2N2M A;  3QRA A;  1MM4 A;  3AAA B;  3HOE A;  2M06 A;  3AAE B;  3SYS A;  4Z3T A;  4N58 A;  4AKR B;  5D5D A;  1BXW A;  3AA6 B;  4RJX A;  4G76 A;  3SY7 A;  2QTK A;  4AYM C;  1E54 A;  4LSF A;  1ORM A;  4KR4 A;  5EE2 A;  3UAQ A;  5ADX K;  5GV0 A;  5DL5 A;  1QJP A;  3AA0 A;  1GFQ A;  4O49 A;  4AYN A;  1ZHY A;  1GFO A;  5IYU A;  4GCS A;  1Q9F A;  2KXP A;  4O3Z A;  3LK4 1;  7PRN A;  3NSG A;  2MNH A;  4GHB A;  1YS5 A;  3TZG A;  3AAA A;  2KC0 A;  3AAE A;  5DL8 A;  4FSP A;  4AKR A;  4D65 A;  4JCH A;  4FZM A;  4N59 A;  3AA6 A;  3LK2 B;  3POU A;  2OMF A;  4AFK A;  3POR A;  2PRN A;  1MM5 A;  4O3Y A;  3KVD D;  2POR A;  3AA7 B;  5DL7 A;  5AFU L;  2J4U P;  4KRA A;  1GFN A;  4FOZ A;  3G7G A;  4QQ1 A;  4U9C A;  1PRN A;  4D5U A;  3UPG A;  1GFM A;  1GFP A;  3WI5 A;  3LK4 2;  4AYE C;  3POX A;  5ADX L;  3T0S A;  1PHO A;  4AYD C;  4LSE A;  2JMM A;  2ODJ A;  3QRC A;  2XG6 A;  3JTY A;  4XNL A;  3LK2 A;  5PRN A;  3WI4 A;  5AFU K;  2J1N A;  4O3X B;  2Y0H A;  5DL6 A;  2Y7S A;  3T24 A;  2KDY A;  4AYI D;  4BUM X;  1ZHT A;  1HXT A; 
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