2XE1A

Molecular insights into clinically isolated ompc mutants and their role in multi-drug resistance
Total Genus 105
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
354
structure length
354
Chain Sequence
AEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQIQGNAPESENNSWTRVAFAGLKFQDIGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGQNGSVSGENDPDFTGHGITNNGRKALRQNGDGVGGSITYDYEGFGVGAAVSSSKRTWDQNNTGLIGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVVAGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGLVYQF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transport protein
source organism Escherichia coli
publication title Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.
pubmed doi rcsb
molecule keywords OUTER MEMBRANE PROTEIN C
total genus 105
structure length 354
sequence length 354
ec nomenclature
pdb deposition date 2010-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00267 Porin_1 Gram-negative porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 2xe1A00
8PRNA 4FMSA 3SY9A 1BT9A 4C69X 1GFPA 2QTKA 3POQA 1GFQA 2J1NA 4D65A 1GFOA 7PRNA 4GCQA 4FSOA 2Y0KA 2Y2XA 2ZFGA 4RJWA 3T0SA 3POXA 4FOZA 4JFBA 3POUA 5FVNA 3VY9X 1OSMA 4AUIA 4RJXA 3O0EA 3JTYA 3HWBA 5DL6A 4FRXA 3EMNX 4FT6A 4GCPA 2ZLDA 4D5UA 4BUMX 5DL8A 4KR8A 1MPFA 2PRNA 1OPFA 2J4UP 3T20A 2OMFA 3SYSA 1GFMA 1GFNA 3PRNA 3UPGA 5DL5A 3PORA 4LSIA 2XE1A 2XE2A 4D64A 3SYBA 3SZVA 1HXUA 4LSEA 6PRNA 3VY8X 2FGQX 1E54A 3SY7A 4FRTA 2PORA 3FYXA 2K4TA 4KR4A 3WI4A 3A2SX 3SZDA 3VZTX 1HXTA 4FSPA 3T24A 2O4VA 2Y0LA 2Y0HA 3VZWX 2FGRA 2XE3A 5JDPA 5DL7A 4LSHA 2XE5A 3K19A 1HXXA 2XG6A 3NSGA 3HW9A 3UU2A 3WI5A 2ODJA 4LSFA 1H6S1 5PRNA 4GCSA 1BH3A 3VZUX 1PHOA 4KRAA 1PRNA
chains in the Genus database with same CATH superfamily
4O4UA 3WU2O 1ORMA 1ZHYA 4UB6O 4G76A 2M06A 3VE1A 4FMSA 8PRNA 5IYUA 4O3YA 3SY9A 1BT9A 5GV0A 1ZHTA 4C69X 1GFPA 2AXTO 2QTKA 2R4OA 3POQA 4AYMC 1G90A 1GFQA 2J1NA 4D65A 3DA4A 3LK42 4O3ZA 1GFOA 5E79O 1S5LO 2JQYA 2XTQA 2F1TA 2YPVA 3DWOX 3PQSA 4FSOA 2Y0KA 2Y2XA 2ZFGA 4GCQA 4RJWA 5G38A 3T0SA 1QJPA 2ERVA 2KZ7A 4U9CA 5H2FO 3POXA 1QJ8A 4FOZA 3LK2A 4JFBA 4C00A 4CTDA 3POUA 5FVNA 4O3XB 5B66O 2KZ7B 3PGSA 4O4XA 3AA0A 3KZIO 3VY9X 4C4VA 1OSMA 3AAAA 4AUIA 2R4PA 4Z3TA 3PGRA 2F1VA 4RJXA 5TISO 4FQEA 3O0EA 3AA0B 4PUXA 3JTYA 4AZLA 5AFUK 3AAAB 1ZHWA 3QRCA 4AKRB 1Q9FA 4G75A 3HWBA 5DL6A 4FRXA 2GE4A 2R89A 5ADXL 1ZHXA 3EMNX 4RL9A 3VE2A 4FT6A 4GCPA 2ZLDA 4D5UA 4BUMX 2M07A 5DL8A 5G26A 1BXWA 4QQ1A 3DZMA 4KR8A 3AA7A 1MPFA 2PRNA 1OPFA 3A0BO 4K3BA 2Y7SA 4PJ0O 2X27X 3HOEA 4AYID 2J4UP 2WJRA 2OMFA 2R8AA 3HOLA 2WVPA 4AYNA 3AA7B 3SYSA 5GTHO 1GFMA 1GFNA 4GF4A 4E1SA 1T16A 3PRNA 2KDYA 3TZGA 3DWNA 2KC0A 2YNKA 3UPGA 5DL5A 4O3WA 2R88A 3BRYA 2N2LA 4AKRA 3PORA 2XE1A 4LSIA 4AYEC 2W81C 3PGUA 3AA6A 4XNKA 5EE2A 2IWVA 3AAEB 1YS5A 5KAIO 2XMXA 3BRZA 2XE2A 3AA6B 5KAFO 4D64A 7PRNA 4IL6O 4FZMA 3SYBA 4O49A 3KVDD 3SZVA 4E1TA 1HXUA 4FZLA 1Q9GA 3G7GA 3QRAA 4LSEA 4GHBA 4PR7A 2FGQX 1E54A 3C5OA 2X9KA 4FRTA 3SY7A 2R4NA 2WJQA 3VY8X 2PORA 4FUVA 3A0HO 3NJTA 3FYXA 2KXPA 2LHFA 4N74A 2K4TA 4KR4A 1PRNA 4RLBA 4UB8O 3WI4A 4AYDC 4F4BA 3A2SX 3SZDA 3GP6A 3VZTX 4AKMA 1HXTA 4N58A 5G3AA 2KXPB 2MNHA 4FESA 3T20A 4FSPA 5B5EO 2F1CX 3T24A 5ADXK 2O4VA 2LFUA 1ZHZA 2Y0LA 2Y0HA 3AAEA 4K3CA 4N59A 2FGRA 1MM5A 2XE3A 3AA1A 3VZWX 5JDPA 5DL7A 2MHLA 3PF1A 4LSHA 4FZNA 5GTIO 1P4TA 2XE5A 3AA1B 3LK3A 3K19A 1HXXA 2XG6A 2XTRA 1QJ9A 3NSGA 3HW9A 2N2MA 3JCUO 3V8UA 3DA3A 4JCHA 3LK3B 2K0LA 2JMMA 3UU2A 3WI5A 3RBHA 4B61A 2ODJA 1IZNA 4LSFA 4XNLA 1H6S1 5PRNA 2IWWA 3BS0A 2R4LA 1IZNB 4GCSA 1MM4A 5D5DA 4C4VB 5AFUL 1BH3A 4AFKA 5T5FA 2W80C 3LK41 4N75A 1T1LA 5G39A 3LK2B 4RLCA 3VZUX 3UAQA 6PRNA 1PHOA 3PQUA 4KRAA 1THQA
chains in the Genus database with same CATH topology
4O4UA 1ORMA 1ZHYA 4G76A 2M06A 3VE1A 4FMSA 8PRNA 5IYUA 4O3YA 3SY9A 1BT9A 5GV0A 1ZHTA 4C69X 1GFPA 2QTKA 3POQA 1G90A 4AYMC 1GFQA 2J1NA 4D65A 3DA4A 3LK42 4O3ZA 1GFOA 5T5FA 2XTQA 2YPVA 4GCQA 2F1TA 4FSOA 4AYID 3PQSA 7PRNA 2Y0KA 2Y2XA 2ZFGA 4RJWA 3T0SA 1QJPA 2ERVA 2KZ7A 4U9CA 3POXA 1QJ8A 4FOZA 3LK2A 4JFBA 3POUA 5FVNA 4O3XB 2KZ7B 3VY9X 4O4XA 3AA0A 1OSMA 3AAAA 4AUIA 4Z3TA 2F1VA 4RJXA 3O0EA 3AA0B 4PUXA 3JTYA 4AZLA 3AAAB 1ZHWA 3QRCA 4AKRB 1Q9FA 4G75A 3HWBA 5DL6A 4FRXA 2GE4A 5ADXL 1ZHXA 3EMNX 4RL9A 3VE2A 4FT6A 4GCPA 2ZLDA 4D5UA 4BUMX 2M07A 5DL8A 5G26A 1BXWA 4QQ1A 4KR8A 3AA7A 1MPFA 2PRNA 1OPFA 2J4UP 3T20A 2Y7SA 2X27X 3HOEA 3HOLA 2OMFA 4AYNA 3AA7B 3SYSA 1GFMA 1GFNA 4GF4A 4E1SA 3PRNA 3TZGA 2KDYA 2KC0A 2YNKA 3UPGA 5DL5A 4O3WA 2N2LA 4AKRA 3PORA 2XE1A 4LSIA 4AYEC 2W81C 3AA6A 4XNKA 5EE2A 3AAEB 1YS5A 2XMXA 2XE2A 3AA6B 4D64A 4FZMA 3SYBA 4O49A 3KVDD 3SZVA 4E1TA 1HXUA 4FZLA 1Q9GA 3G7GA 3QRAA 4LSEA 4GHBA 3VY8X 2FGQX 1E54A 3C5OA 4FRTA 3SY7A 5AFUK 6PRNA 2PORA 4FUVA 3FYXA 2KXPA 2LHFA 4RLBA 2K4TA 4KR4A 1PRNA 3WI4A 4AYDC 4F4BA 3A2SX 3SZDA 3GP6A 3VZTX 4AKMA 1HXTA 4N58A 2KXPB 2MNHA 4FESA 4FSPA 3T24A 5ADXK 2O4VA 2LFUA 1ZHZA 2Y0LA 2Y0HA 3AAEA 4N59A 2FGRA 1MM5A 2XE3A 3AA1A 3VZWX 5JDPA 5DL7A 2MHLA 4LSHA 4FZNA 1P4TA 2XE5A 3AA1B 3LK3A 3K19A 1HXXA 2XG6A 2XTRA 1QJ9A 3NSGA 3HW9A 2N2MA 3V8UA 3DA3A 4JCHA 3LK3B 2K0LA 2JMMA 3UU2A 3WI5A 3RBHA 4B61A 2ODJA 1IZNA 4LSFA 4XNLA 1H6S1 5PRNA 1IZNB 4GCSA 1MM4A 5D5DA 5AFUL 1BH3A 4AFKA 2W80C 3LK41 3LK2B 4RLCA 3VZUX 3UAQA 1PHOA 3PQUA 4KRAA 1THQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 8PRN A;  4FMS A;  3SY9 A;  1BT9 A;  4C69 X;  1GFP A;  2QTK A;  3POQ A;  1GFQ A;  2J1N A;  4D65 A;  1GFO A;  7PRN A;  4GCQ A;  4FSO A;  2Y0K A;  2Y2X A;  2ZFG A;  4RJW A;  3T0S A;  3POX A;  4FOZ A;  4JFB A;  3POU A;  5FVN A;  3VY9 X;  1OSM A;  4AUI A;  4RJX A;  3O0E A;  3JTY A;  3HWB A;  5DL6 A;  4FRX A;  3EMN X;  4FT6 A;  4GCP A;  2ZLD A;  4D5U A;  4BUM X;  5DL8 A;  4KR8 A;  1MPF A;  2PRN A;  1OPF A;  2J4U P;  3T20 A;  2OMF A;  3SYS A;  1GFM A;  1GFN A;  3PRN A;  3UPG A;  5DL5 A;  3POR A;  4LSI A;  2XE1 A;  2XE2 A;  4D64 A;  3SYB A;  3SZV A;  1HXU A;  4LSE A;  6PRN A;  3VY8 X;  2FGQ X;  1E54 A;  3SY7 A;  4FRT A;  2POR A;  3FYX A;  2K4T A;  4KR4 A;  3WI4 A;  3A2S X;  3SZD A;  3VZT X;  1HXT A;  4FSP A;  3T24 A;  2O4V A;  2Y0L A;  2Y0H A;  3VZW X;  2FGR A;  2XE3 A;  5JDP A;  5DL7 A;  4LSH A;  2XE5 A;  3K19 A;  1HXX A;  2XG6 A;  3NSG A;  3HW9 A;  3UU2 A;  3WI5 A;  2ODJ A;  4LSF A;  1H6S 1;  5PRN A;  4GCS A;  1BH3 A;  3VZU X;  1PHO A;  4KRA A;  1PRN A; 
#chains in the Genus database with same CATH topology
 4O4U A;  3WU2 O;  1ORM A;  1ZHY A;  4UB6 O;  4G76 A;  2M06 A;  3VE1 A;  4FMS A;  8PRN A;  5IYU A;  4O3Y A;  3SY9 A;  1BT9 A;  5GV0 A;  1ZHT A;  4C69 X;  1GFP A;  2AXT O;  2QTK A;  2R4O A;  3POQ A;  4AYM C;  1G90 A;  1GFQ A;  2J1N A;  4D65 A;  3DA4 A;  3LK4 2;  4O3Z A;  1GFO A;  5E79 O;  1S5L O;  2JQY A;  2XTQ A;  2F1T A;  2YPV A;  3DWO X;  3PQS A;  4FSO A;  2Y0K A;  2Y2X A;  2ZFG A;  4GCQ A;  4RJW A;  5G38 A;  3T0S A;  1QJP A;  2ERV A;  2KZ7 A;  4U9C A;  5H2F O;  3POX A;  1QJ8 A;  4FOZ A;  3LK2 A;  4JFB A;  4C00 A;  4CTD A;  3POU A;  5FVN A;  4O3X B;  5B66 O;  2KZ7 B;  3PGS A;  4O4X A;  3AA0 A;  3KZI O;  3VY9 X;  4C4V A;  1OSM A;  3AAA A;  4AUI A;  2R4P A;  4Z3T A;  3PGR A;  2F1V A;  4RJX A;  5TIS O;  4FQE A;  3O0E A;  3AA0 B;  4PUX A;  3JTY A;  4AZL A;  5AFU K;  3AAA B;  1ZHW A;  3QRC A;  4AKR B;  1Q9F A;  4G75 A;  3HWB A;  5DL6 A;  4FRX A;  2GE4 A;  2R89 A;  5ADX L;  1ZHX A;  3EMN X;  4RL9 A;  3VE2 A;  4FT6 A;  4GCP A;  2ZLD A;  4D5U A;  4BUM X;  2M07 A;  5DL8 A;  5G26 A;  1BXW A;  4QQ1 A;  3DZM A;  4KR8 A;  3AA7 A;  1MPF A;  2PRN A;  1OPF A;  3A0B O;  4K3B A;  2Y7S A;  4PJ0 O;  2X27 X;  3HOE A;  4AYI D;  2J4U P;  2WJR A;  2OMF A;  2R8A A;  3HOL A;  2WVP A;  4AYN A;  3AA7 B;  3SYS A;  5GTH O;  1GFM A;  1GFN A;  4GF4 A;  4E1S A;  1T16 A;  3PRN A;  2KDY A;  3TZG A;  3DWN A;  2KC0 A;  2YNK A;  3UPG A;  5DL5 A;  4O3W A;  2R88 A;  3BRY A;  2N2L A;  4AKR A;  3POR A;  2XE1 A;  4LSI A;  4AYE C;  2W81 C;  3PGU A;  3AA6 A;  4XNK A;  5EE2 A;  2IWV A;  3AAE B;  1YS5 A;  5KAI O;  2XMX A;  3BRZ A;  2XE2 A;  3AA6 B;  5KAF O;  4D64 A;  7PRN A;  4IL6 O;  4FZM A;  3SYB A;  4O49 A;  3KVD D;  3SZV A;  4E1T A;  1HXU A;  4FZL A;  1Q9G A;  3G7G A;  3QRA A;  4LSE A;  4GHB A;  4PR7 A;  2FGQ X;  1E54 A;  3C5O A;  2X9K A;  4FRT A;  3SY7 A;  2R4N A;  2WJQ A;  3VY8 X;  2POR A;  4FUV A;  3A0H O;  3NJT A;  3FYX A;  2KXP A;  2LHF A;  4N74 A;  2K4T A;  4KR4 A;  1PRN A;  4RLB A;  4UB8 O;  3WI4 A;  4AYD C;  4F4B A;  3A2S X;  3SZD A;  3GP6 A;  3VZT X;  4AKM A;  1HXT A;  4N58 A;  5G3A A;  2KXP B;  2MNH A;  4FES A;  3T20 A;  4FSP A;  5B5E O;  2F1C X;  3T24 A;  5ADX K;  2O4V A;  2LFU A;  1ZHZ A;  2Y0L A;  2Y0H A;  3AAE A;  4K3C A;  4N59 A;  2FGR A;  1MM5 A;  2XE3 A;  3AA1 A;  3VZW X;  5JDP A;  5DL7 A;  2MHL A;  3PF1 A;  4LSH A;  4FZN A;  5GTI O;  1P4T A;  2XE5 A;  3AA1 B;  3LK3 A;  3K19 A;  1HXX A;  2XG6 A;  2XTR A;  1QJ9 A;  3NSG A;  3HW9 A;  2N2M A;  3JCU O;  3V8U A;  3DA3 A;  4JCH A;  3LK3 B;  2K0L A;  2JMM A;  3UU2 A;  3WI5 A;  3RBH A;  4B61 A;  2ODJ A;  1IZN A;  4LSF A;  4XNL A;  1H6S 1;  5PRN A;  2IWW A;  3BS0 A;  2R4L A;  1IZN B;  4GCS A;  1MM4 A;  5D5D A;  4C4V B;  5AFU L;  1BH3 A;  4AFK A;  5T5F A;  2W80 C;  3LK4 1;  4N75 A;  1T1L A;  5G39 A;  3LK2 B;  4RLC A;  3VZU X;  3UAQ A;  6PRN A;  1PHO A;  3PQU A;  4KRA A;  1THQ A; 
#chains in the Genus database with same CATH homology
 4O4U A;  1ORM A;  1ZHY A;  4G76 A;  2M06 A;  3VE1 A;  4FMS A;  8PRN A;  5IYU A;  4O3Y A;  3SY9 A;  1BT9 A;  5GV0 A;  1ZHT A;  4C69 X;  1GFP A;  2QTK A;  3POQ A;  1G90 A;  4AYM C;  1GFQ A;  2J1N A;  4D65 A;  3DA4 A;  3LK4 2;  4O3Z A;  1GFO A;  5T5F A;  2XTQ A;  2YPV A;  4GCQ A;  2F1T A;  4FSO A;  4AYI D;  3PQS A;  7PRN A;  2Y0K A;  2Y2X A;  2ZFG A;  4RJW A;  3T0S A;  1QJP A;  2ERV A;  2KZ7 A;  4U9C A;  3POX A;  1QJ8 A;  4FOZ A;  3LK2 A;  4JFB A;  3POU A;  5FVN A;  4O3X B;  2KZ7 B;  3VY9 X;  4O4X A;  3AA0 A;  1OSM A;  3AAA A;  4AUI A;  4Z3T A;  2F1V A;  4RJX A;  3O0E A;  3AA0 B;  4PUX A;  3JTY A;  4AZL A;  3AAA B;  1ZHW A;  3QRC A;  4AKR B;  1Q9F A;  4G75 A;  3HWB A;  5DL6 A;  4FRX A;  2GE4 A;  5ADX L;  1ZHX A;  3EMN X;  4RL9 A;  3VE2 A;  4FT6 A;  4GCP A;  2ZLD A;  4D5U A;  4BUM X;  2M07 A;  5DL8 A;  5G26 A;  1BXW A;  4QQ1 A;  4KR8 A;  3AA7 A;  1MPF A;  2PRN A;  1OPF A;  2J4U P;  3T20 A;  2Y7S A;  2X27 X;  3HOE A;  3HOL A;  2OMF A;  4AYN A;  3AA7 B;  3SYS A;  1GFM A;  1GFN A;  4GF4 A;  4E1S A;  3PRN A;  3TZG A;  2KDY A;  2KC0 A;  2YNK A;  3UPG A;  5DL5 A;  4O3W A;  2N2L A;  4AKR A;  3POR A;  2XE1 A;  4LSI A;  4AYE C;  2W81 C;  3AA6 A;  4XNK A;  5EE2 A;  3AAE B;  1YS5 A;  2XMX A;  2XE2 A;  3AA6 B;  4D64 A;  4FZM A;  3SYB A;  4O49 A;  3KVD D;  3SZV A;  4E1T A;  1HXU A;  4FZL A;  1Q9G A;  3G7G A;  3QRA A;  4LSE A;  4GHB A;  3VY8 X;  2FGQ X;  1E54 A;  3C5O A;  4FRT A;  3SY7 A;  5AFU K;  6PRN A;  2POR A;  4FUV A;  3FYX A;  2KXP A;  2LHF A;  4RLB A;  2K4T A;  4KR4 A;  1PRN A;  3WI4 A;  4AYD C;  4F4B A;  3A2S X;  3SZD A;  3GP6 A;  3VZT X;  4AKM A;  1HXT A;  4N58 A;  2KXP B;  2MNH A;  4FES A;  4FSP A;  3T24 A;  5ADX K;  2O4V A;  2LFU A;  1ZHZ A;  2Y0L A;  2Y0H A;  3AAE A;  4N59 A;  2FGR A;  1MM5 A;  2XE3 A;  3AA1 A;  3VZW X;  5JDP A;  5DL7 A;  2MHL A;  4LSH A;  4FZN A;  1P4T A;  2XE5 A;  3AA1 B;  3LK3 A;  3K19 A;  1HXX A;  2XG6 A;  2XTR A;  1QJ9 A;  3NSG A;  3HW9 A;  2N2M A;  3V8U A;  3DA3 A;  4JCH A;  3LK3 B;  2K0L A;  2JMM A;  3UU2 A;  3WI5 A;  3RBH A;  4B61 A;  2ODJ A;  1IZN A;  4LSF A;  4XNL A;  1H6S 1;  5PRN A;  1IZN B;  4GCS A;  1MM4 A;  5D5D A;  5AFU L;  1BH3 A;  4AFK A;  2W80 C;  3LK4 1;  3LK2 B;  4RLC A;  3VZU X;  3UAQ A;  1PHO A;  3PQU A;  4KRA A;  1THQ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...