2XG6A

Molecular insights into clinically isolated ompc mutants and their role in multi-drug resistance
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
343
structure length
343
Chain Sequence
AEIYNKDGNKLDLYGKVEGLHYFSDNDSKDGDKTYMRLGFKGETQVTDQLTGYGQWEYQIQGNEPESDNSSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYDSDNFMQQHGNGFATYRNTDFFGLVDGLDFAVQYQGKNGSAHGEGMTTNGRDDVFEQNGDGVGGSITYNYEGFGIGAAVSSSKRTWDQNNTGLIGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPFLAYLQSKGKNLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNRFTRDAGINTDDIVALGLVYQF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
source organism Escherichia coli
publication title Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.
pubmed doi rcsb
molecule keywords OMPC
total genus 87
structure length 343
sequence length 343
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2010-05-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00267 Porin_1 Gram-negative porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 2xg6A00
4FSOA 3FYXA 3POQA 3POUA 1GFMA 3SZVA 4D64A 3K19A 2ZLDA 5PRNA 1PHOA 4KR8A 5JDPA 1BH3A 3POXA 3PRNA 2ZFGA 1GFQA 4RJXA 8PRNA 2Y0KA 2FGQX 3T20A 3VY8X 3SZDA 4C69X 4KRAA 3PORA 3SYBA 4FMSA 5DL8A 1HXTA 2Y0HA 4D5UA 4GCQA 3EMNX 4GCPA 4KR4A 1OPFA 4FT6A 1GFOA 3O0EA 4GCSA 3HWBA 6PRNA 3VY9X 3WI4A 3UPGA 1PRNA 2QTKA 2XE1A 2XE3A 5DL6A 4RJWA 2OMFA 2FGRA 2J4UP 1HXUA 2ODJA 3SYSA 2XG6A 2O4VA 3WI5A 3SY7A 5FVNA 3VZUX 5DL5A 4FRXA 4LSFA 1MPFA 4D65A 2Y2XA 3NSGA 5DL7A 2K4TA 4FRTA 3VZTX 1OSMA 4AUIA 3SY9A 1HXXA 3JTYA 2J1NA 2XE2A 3T24A 1E54A 3UU2A 7PRNA 2Y0LA 1H6S1 3T0SA 3A2SX 4FOZA 1GFPA 1BT9A 4LSHA 1GFNA 2XE5A 2PORA 4JFBA 4LSIA 4BUMX 3HW9A 2PRNA 4LSEA 3VZWX 4FSPA
chains in the Genus database with same CATH superfamily
2W81C 4FSOA 1IZNA 4E1SA 1BXWA 3FYXA 3POQA 3LK42 3POUA 5GV0A 5GTIO 2LHFA 1GFMA 2K0LA 3SZVA 2KZ7B 5G38A 3DZMA 3LK2B 4PR7A 4D64A 3K19A 4PJ0O 2ZLDA 5PRNA 1PHOA 4F4BA 4O49A 4KR8A 5JDPA 1MM5A 3AA1A 1BH3A 3POXA 3PRNA 4O3WA 3VE1A 4N75A 3PGSA 1ZHTA 2ZFGA 4RL9A 3PQSA 1GFQA 2XTRA 4AFKA 3RBHA 1T1LA 3PGUA 4RJXA 2LFUA 2Y0KA 2FGQX 8PRNA 2WJQA 5ADXK 3T20A 1S5LO 5EE2A 3SZDA 3VY8X 2MHLA 1ORMA 3AA1B 4C69X 4KRAA 4AYID 4AZLA 2MNHA 3PORA 3SYBA 3PQUA 4AYEC 4FMSA 2X27X 3G7GA 4O3XB 1HXTA 2Y0HA 5DL8A 4C4VB 2IWWA 1Q9GA 4N58A 4K3BA 4D5UA 5T5FA 2R88A 3GP6A 2KC0A 3JCUO 4FUVA 2R4NA 1P4TA 4GCQA 3EMNX 5D5DA 4GCPA 3LK41 2X9KA 1IZNB 5IYUA 4FZLA 3QRCA 2N2LA 4XNKA 3KZIO 2Y7SA 4KR4A 1QJ8A 1G90A 1OPFA 2WVPA 4FT6A 1GFOA 4AKRA 3O0EA 2XTQA 3V8UA 2N2MA 3AAAA 4GCSA 4AYDC 1QJPA 2WJRA 5AFUK 5G3AA 3HOLA 3HWBA 4PUXA 3VY9X 3WI4A 6PRNA 5E79O 4FQEA 2F1TA 3AA0A 3UPGA 2R4OA 1QJ9A 3A0HO 3AA7A 1THQA 3AAEA 1PRNA 3AA6A 5B5EO 2AXTO 5ADXL 3DA3A 2QTKA 3TZGA 2XE1A 2R4LA 2XE3A 3BS0A 2R4PA 5DL6A 4AKRB 4Z3TA 4RJWA 2OMFA 2W80C 3AAAB 4FZMA 4O4XA 2FGRA 4O3ZA 1HXUA 2ODJA 3SYSA 2J4UP 2M06A 2XG6A 2R89A 2O4VA 3A0BO 3AA0B 4AKMA 3WI5A 4B61A 5G26A 3AA7B 1T16A 3DWOX 3SY7A 3AA6B 4AYNA 5GTHO 4N59A 4RLBA 5G39A 2KDYA 3DWNA 2YPVA 5KAIO 1MM4A 5FVNA 3NJTA 3VZUX 5DL5A 3BRYA 2KXPA 4FRXA 5KAFO 2F1CX 1MPFA 4LSFA 4D65A 1ZHZA 2Y2XA 3HOEA 3NSGA 2K4TA 2GE4A 2F1VA 1ZHYA 4IL6O 5DL7A 5H2FO 2XMXA 4FRTA 3VZTX 3BRZA 5TISO 4FESA 5AFUL 4CTDA 3QRAA 4G76A 1Q9FA 4GHBA 2IWVA 4QQ1A 1OSMA 4AUIA 3SY9A 1HXXA 2JQYA 2YNKA 2KXPB 2M07A 3JTYA 3LK3A 4FZNA 3UAQA 2J1NA 2R8AA 2XE2A 3KVDD 3T24A 3PGRA 4AYMC 1E54A 3UU2A 4K3CA 7PRNA 2JMMA 1H6S1 2ERVA 2Y0LA 4GF4A 3T0SA 3A2SX 4FOZA 4E1TA 4O4UA 4JCHA 1GFPA 3AAEB 4U9CA 4C4VA 3DA4A 4N74A 4O3YA 3WU2O 4C00A 3PF1A 4RLCA 3LK3B 5B66O 1BT9A 1ZHXA 4LSHA 1GFNA 2XE5A 2PORA 4JFBA 2KZ7A 3C5OA 4LSIA 4UB6O 4XNLA 4BUMX 3HW9A 2PRNA 4G75A 3LK2A 4LSEA 3VZWX 1YS5A 4UB8O 3VE2A 4FSPA 1ZHWA
chains in the Genus database with same CATH topology
2W81C 4FSOA 1IZNA 4E1SA 1BXWA 3FYXA 3POQA 3LK42 3POUA 5GV0A 2LHFA 1GFMA 2K0LA 3SZVA 2KZ7B 3LK2B 4D64A 3K19A 2ZLDA 5PRNA 1PHOA 4F4BA 4O49A 4KR8A 5JDPA 1MM5A 3AA1A 1BH3A 3POXA 3PRNA 4O3WA 3VE1A 1ZHTA 2ZFGA 4RL9A 3PQSA 1GFQA 2XTRA 4AFKA 3RBHA 4RJXA 8PRNA 2LFUA 2Y0KA 2FGQX 5ADXK 3T20A 5EE2A 3SZDA 3VY8X 2MHLA 1ORMA 3AA1B 4C69X 4KRAA 4AYID 4AZLA 2MNHA 3PORA 3SYBA 3PQUA 4AYEC 4FMSA 2X27X 3G7GA 4O3XB 1HXTA 2Y0HA 5DL8A 1Q9GA 4N58A 4D5UA 5T5FA 3GP6A 2KC0A 4FUVA 1P4TA 4GCQA 3EMNX 5D5DA 4GCPA 3LK41 1IZNB 5IYUA 4FZLA 3QRCA 2N2LA 4XNKA 2Y7SA 4KR4A 1QJ8A 1G90A 1OPFA 4FT6A 1GFOA 4AKRA 3O0EA 2XTQA 3V8UA 2N2MA 3AAAA 4GCSA 4AYDC 1QJPA 5AFUK 3HOLA 3HWBA 4PUXA 3VY9X 3WI4A 6PRNA 3UPGA 2F1TA 3AA0A 1QJ9A 3AA7A 1THQA 3AAEA 1PRNA 3AA6A 5ADXL 3DA3A 2QTKA 3TZGA 2XE1A 2XE3A 4AKRB 4Z3TA 5DL6A 4RJWA 2OMFA 2W80C 3AAAB 4FZMA 4O4XA 2FGRA 4O3ZA 1HXUA 2ODJA 3SYSA 2J4UP 2M06A 2XG6A 2O4VA 3AA0B 4AKMA 4B61A 3WI5A 5G26A 3AA7B 3SY7A 3AA6B 4AYNA 4N59A 4RLBA 2KDYA 2YPVA 1MM4A 5FVNA 3VZUX 5DL5A 4FRXA 2KXPA 4LSFA 1MPFA 4D65A 1ZHZA 2Y2XA 3HOEA 3NSGA 2K4TA 2GE4A 2F1VA 1ZHYA 5DL7A 2XMXA 4FRTA 3VZTX 4FESA 5AFUL 3QRAA 4G76A 1Q9FA 4GHBA 4QQ1A 1OSMA 4AUIA 3SY9A 1HXXA 2YNKA 3JTYA 2KXPB 2M07A 3LK3A 4FZNA 3UAQA 2J1NA 2XE2A 3KVDD 3T24A 4AYMC 1E54A 3UU2A 7PRNA 2JMMA 1H6S1 2ERVA 2Y0LA 4GF4A 3T0SA 3A2SX 4FOZA 4E1TA 4O4UA 4JCHA 1GFPA 3AAEB 4U9CA 3DA4A 4O3YA 4RLCA 3LK3B 1BT9A 1ZHXA 4LSHA 1GFNA 2XE5A 2PORA 4JFBA 2KZ7A 3C5OA 4LSIA 4XNLA 4BUMX 3HW9A 2PRNA 4G75A 3LK2A 4LSEA 3VZWX 1YS5A 3VE2A 4FSPA 1ZHWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FSO A;  3FYX A;  3POQ A;  3POU A;  1GFM A;  3SZV A;  4D64 A;  3K19 A;  2ZLD A;  5PRN A;  1PHO A;  4KR8 A;  5JDP A;  1BH3 A;  3POX A;  3PRN A;  2ZFG A;  1GFQ A;  4RJX A;  8PRN A;  2Y0K A;  2FGQ X;  3T20 A;  3VY8 X;  3SZD A;  4C69 X;  4KRA A;  3POR A;  3SYB A;  4FMS A;  5DL8 A;  1HXT A;  2Y0H A;  4D5U A;  4GCQ A;  3EMN X;  4GCP A;  4KR4 A;  1OPF A;  4FT6 A;  1GFO A;  3O0E A;  4GCS A;  3HWB A;  6PRN A;  3VY9 X;  3WI4 A;  3UPG A;  1PRN A;  2QTK A;  2XE1 A;  2XE3 A;  5DL6 A;  4RJW A;  2OMF A;  2FGR A;  2J4U P;  1HXU A;  2ODJ A;  3SYS A;  2XG6 A;  2O4V A;  3WI5 A;  3SY7 A;  5FVN A;  3VZU X;  5DL5 A;  4FRX A;  4LSF A;  1MPF A;  4D65 A;  2Y2X A;  3NSG A;  5DL7 A;  2K4T A;  4FRT A;  3VZT X;  1OSM A;  4AUI A;  3SY9 A;  1HXX A;  3JTY A;  2J1N A;  2XE2 A;  3T24 A;  1E54 A;  3UU2 A;  7PRN A;  2Y0L A;  1H6S 1;  3T0S A;  3A2S X;  4FOZ A;  1GFP A;  1BT9 A;  4LSH A;  1GFN A;  2XE5 A;  2POR A;  4JFB A;  4LSI A;  4BUM X;  3HW9 A;  2PRN A;  4LSE A;  3VZW X;  4FSP A; 
#chains in the Genus database with same CATH topology
 2W81 C;  4FSO A;  1IZN A;  4E1S A;  1BXW A;  3FYX A;  3POQ A;  3LK4 2;  3POU A;  5GV0 A;  5GTI O;  2LHF A;  1GFM A;  2K0L A;  3SZV A;  2KZ7 B;  5G38 A;  3DZM A;  3LK2 B;  4PR7 A;  4D64 A;  3K19 A;  4PJ0 O;  2ZLD A;  5PRN A;  1PHO A;  4F4B A;  4O49 A;  4KR8 A;  5JDP A;  1MM5 A;  3AA1 A;  1BH3 A;  3POX A;  3PRN A;  4O3W A;  3VE1 A;  4N75 A;  3PGS A;  1ZHT A;  2ZFG A;  4RL9 A;  3PQS A;  1GFQ A;  2XTR A;  4AFK A;  3RBH A;  1T1L A;  3PGU A;  4RJX A;  2LFU A;  2Y0K A;  2FGQ X;  8PRN A;  2WJQ A;  5ADX K;  3T20 A;  1S5L O;  5EE2 A;  3SZD A;  3VY8 X;  2MHL A;  1ORM A;  3AA1 B;  4C69 X;  4KRA A;  4AYI D;  4AZL A;  2MNH A;  3POR A;  3SYB A;  3PQU A;  4AYE C;  4FMS A;  2X27 X;  3G7G A;  4O3X B;  1HXT A;  2Y0H A;  5DL8 A;  4C4V B;  2IWW A;  1Q9G A;  4N58 A;  4K3B A;  4D5U A;  5T5F A;  2R88 A;  3GP6 A;  2KC0 A;  3JCU O;  4FUV A;  2R4N A;  1P4T A;  4GCQ A;  3EMN X;  5D5D A;  4GCP A;  3LK4 1;  2X9K A;  1IZN B;  5IYU A;  4FZL A;  3QRC A;  2N2L A;  4XNK A;  3KZI O;  2Y7S A;  4KR4 A;  1QJ8 A;  1G90 A;  1OPF A;  2WVP A;  4FT6 A;  1GFO A;  4AKR A;  3O0E A;  2XTQ A;  3V8U A;  2N2M A;  3AAA A;  4GCS A;  4AYD C;  1QJP A;  2WJR A;  5AFU K;  5G3A A;  3HOL A;  3HWB A;  4PUX A;  3VY9 X;  3WI4 A;  6PRN A;  5E79 O;  4FQE A;  2F1T A;  3AA0 A;  3UPG A;  2R4O A;  1QJ9 A;  3A0H O;  3AA7 A;  1THQ A;  3AAE A;  1PRN A;  3AA6 A;  5B5E O;  2AXT O;  5ADX L;  3DA3 A;  2QTK A;  3TZG A;  2XE1 A;  2R4L A;  2XE3 A;  3BS0 A;  2R4P A;  5DL6 A;  4AKR B;  4Z3T A;  4RJW A;  2OMF A;  2W80 C;  3AAA B;  4FZM A;  4O4X A;  2FGR A;  4O3Z A;  1HXU A;  2ODJ A;  3SYS A;  2J4U P;  2M06 A;  2XG6 A;  2R89 A;  2O4V A;  3A0B O;  3AA0 B;  4AKM A;  3WI5 A;  4B61 A;  5G26 A;  3AA7 B;  1T16 A;  3DWO X;  3SY7 A;  3AA6 B;  4AYN A;  5GTH O;  4N59 A;  4RLB A;  5G39 A;  2KDY A;  3DWN A;  2YPV A;  5KAI O;  1MM4 A;  5FVN A;  3NJT A;  3VZU X;  5DL5 A;  3BRY A;  2KXP A;  4FRX A;  5KAF O;  2F1C X;  1MPF A;  4LSF A;  4D65 A;  1ZHZ A;  2Y2X A;  3HOE A;  3NSG A;  2K4T A;  2GE4 A;  2F1V A;  1ZHY A;  4IL6 O;  5DL7 A;  5H2F O;  2XMX A;  4FRT A;  3VZT X;  3BRZ A;  5TIS O;  4FES A;  5AFU L;  4CTD A;  3QRA A;  4G76 A;  1Q9F A;  4GHB A;  2IWV A;  4QQ1 A;  1OSM A;  4AUI A;  3SY9 A;  1HXX A;  2JQY A;  2YNK A;  2KXP B;  2M07 A;  3JTY A;  3LK3 A;  4FZN A;  3UAQ A;  2J1N A;  2R8A A;  2XE2 A;  3KVD D;  3T24 A;  3PGR A;  4AYM C;  1E54 A;  3UU2 A;  4K3C A;  7PRN A;  2JMM A;  1H6S 1;  2ERV A;  2Y0L A;  4GF4 A;  3T0S A;  3A2S X;  4FOZ A;  4E1T A;  4O4U A;  4JCH A;  1GFP A;  3AAE B;  4U9C A;  4C4V A;  3DA4 A;  4N74 A;  4O3Y A;  3WU2 O;  4C00 A;  3PF1 A;  4RLC A;  3LK3 B;  5B66 O;  1BT9 A;  1ZHX A;  4LSH A;  1GFN A;  2XE5 A;  2POR A;  4JFB A;  2KZ7 A;  3C5O A;  4LSI A;  4UB6 O;  4XNL A;  4BUM X;  3HW9 A;  2PRN A;  4G75 A;  3LK2 A;  4LSE A;  3VZW X;  1YS5 A;  4UB8 O;  3VE2 A;  4FSP A;  1ZHW A; 
#chains in the Genus database with same CATH homology
 2W81 C;  4FSO A;  1IZN A;  4E1S A;  1BXW A;  3FYX A;  3POQ A;  3LK4 2;  3POU A;  5GV0 A;  2LHF A;  1GFM A;  2K0L A;  3SZV A;  2KZ7 B;  3LK2 B;  4D64 A;  3K19 A;  2ZLD A;  5PRN A;  1PHO A;  4F4B A;  4O49 A;  4KR8 A;  5JDP A;  1MM5 A;  3AA1 A;  1BH3 A;  3POX A;  3PRN A;  4O3W A;  3VE1 A;  1ZHT A;  2ZFG A;  4RL9 A;  3PQS A;  1GFQ A;  2XTR A;  4AFK A;  3RBH A;  4RJX A;  8PRN A;  2LFU A;  2Y0K A;  2FGQ X;  5ADX K;  3T20 A;  5EE2 A;  3SZD A;  3VY8 X;  2MHL A;  1ORM A;  3AA1 B;  4C69 X;  4KRA A;  4AYI D;  4AZL A;  2MNH A;  3POR A;  3SYB A;  3PQU A;  4AYE C;  4FMS A;  2X27 X;  3G7G A;  4O3X B;  1HXT A;  2Y0H A;  5DL8 A;  1Q9G A;  4N58 A;  4D5U A;  5T5F A;  3GP6 A;  2KC0 A;  4FUV A;  1P4T A;  4GCQ A;  3EMN X;  5D5D A;  4GCP A;  3LK4 1;  1IZN B;  5IYU A;  4FZL A;  3QRC A;  2N2L A;  4XNK A;  2Y7S A;  4KR4 A;  1QJ8 A;  1G90 A;  1OPF A;  4FT6 A;  1GFO A;  4AKR A;  3O0E A;  2XTQ A;  3V8U A;  2N2M A;  3AAA A;  4GCS A;  4AYD C;  1QJP A;  5AFU K;  3HOL A;  3HWB A;  4PUX A;  3VY9 X;  3WI4 A;  6PRN A;  3UPG A;  2F1T A;  3AA0 A;  1QJ9 A;  3AA7 A;  1THQ A;  3AAE A;  1PRN A;  3AA6 A;  5ADX L;  3DA3 A;  2QTK A;  3TZG A;  2XE1 A;  2XE3 A;  4AKR B;  4Z3T A;  5DL6 A;  4RJW A;  2OMF A;  2W80 C;  3AAA B;  4FZM A;  4O4X A;  2FGR A;  4O3Z A;  1HXU A;  2ODJ A;  3SYS A;  2J4U P;  2M06 A;  2XG6 A;  2O4V A;  3AA0 B;  4AKM A;  4B61 A;  3WI5 A;  5G26 A;  3AA7 B;  3SY7 A;  3AA6 B;  4AYN A;  4N59 A;  4RLB A;  2KDY A;  2YPV A;  1MM4 A;  5FVN A;  3VZU X;  5DL5 A;  4FRX A;  2KXP A;  4LSF A;  1MPF A;  4D65 A;  1ZHZ A;  2Y2X A;  3HOE A;  3NSG A;  2K4T A;  2GE4 A;  2F1V A;  1ZHY A;  5DL7 A;  2XMX A;  4FRT A;  3VZT X;  4FES A;  5AFU L;  3QRA A;  4G76 A;  1Q9F A;  4GHB A;  4QQ1 A;  1OSM A;  4AUI A;  3SY9 A;  1HXX A;  2YNK A;  3JTY A;  2KXP B;  2M07 A;  3LK3 A;  4FZN A;  3UAQ A;  2J1N A;  2XE2 A;  3KVD D;  3T24 A;  4AYM C;  1E54 A;  3UU2 A;  7PRN A;  2JMM A;  1H6S 1;  2ERV A;  2Y0L A;  4GF4 A;  3T0S A;  3A2S X;  4FOZ A;  4E1T A;  4O4U A;  4JCH A;  1GFP A;  3AAE B;  4U9C A;  3DA4 A;  4O3Y A;  4RLC A;  3LK3 B;  1BT9 A;  1ZHX A;  4LSH A;  1GFN A;  2XE5 A;  2POR A;  4JFB A;  2KZ7 A;  3C5O A;  4LSI A;  4XNL A;  4BUM X;  3HW9 A;  2PRN A;  4G75 A;  3LK2 A;  4LSE A;  3VZW X;  1YS5 A;  3VE2 A;  4FSP A;  1ZHW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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