2XG6A

Molecular insights into clinically isolated ompc mutants and their role in multi-drug resistance
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
343
structure length
343
Chain Sequence
AEIYNKDGNKLDLYGKVEGLHYFSDNDSKDGDKTYMRLGFKGETQVTDQLTGYGQWEYQIQGNEPESDNSSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYDSDNFMQQHGNGFATYRNTDFFGLVDGLDFAVQYQGKNGSAHGEGMTTNGRDDVFEQNGDGVGGSITYNYEGFGIGAAVSSSKRTWDQNNTGLIGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPFLAYLQSKGKNLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNRFTRDAGINTDDIVALGLVYQF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords OMPC
total genus 87
structure length 343
sequence length 343
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2010-05-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00267 Porin_1 Gram-negative porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 2xg6A00
3VZUX 3PRNA 4BUMX 4D5UA 4D64A 5DL6A 8PRNA 1PHOA 4FSPA 1GFOA 2XG6A 4LSHA 5JDPA 1HXXA 3POXA 3POUA 1HXUA 1MPFA 3SYBA 1GFQA 4AUIA 2XE3A 5DL8A 4LSIA 2Y0LA 1H6S1 4RJWA 2ZFGA 3SY9A 2XE2A 4FOZA 1E54A 5DL7A 1HXTA 2FGRA 3SZDA 3FYXA 3NSGA 4LSEA 4KR8A 3T0SA 1OSMA 2XE5A 4FSOA 4GCSA 4FRTA 4GCPA 2XE1A 4FT6A 3T20A 2J4UP 3T24A 1BH3A 4LSFA 2O4VA 4FRXA 3SYSA 4D65A 3PORA 3SZVA 2QTKA 3JTYA 3POQA 2ZLDA 3UU2A 2PORA 4KRAA 2K4TA 4KR4A 3VZTX 2J1NA 3HW9A 4JFBA 3A2SX 3HWBA 5DL5A 3UPGA 5PRNA 3WI5A 1OPFA 2OMFA 3EMNX 5FVNA 6PRNA 3VZWX 3WI4A 3VY9X 2PRNA 3VY8X 2Y0HA 4C69X 2Y0KA 3SY7A 1GFPA 3K19A 3O0EA 7PRNA 2FGQX 4FMSA 1BT9A 1GFNA 2ODJA 4RJXA 1GFMA 4GCQA 1PRNA 2Y2XA
chains in the Genus database with same CATH superfamily
2R8AA 3VZUX 1G90A 3PRNA 2JQYA 4GF4A 5G38A 4BUMX 4PUXA 3PGUA 4D5UA 3DWOX 4N75A 3DWNA 4D64A 5GV0A 5DL6A 8PRNA 1PHOA 5AFUK 3QRAA 4FSPA 4O4XA 3TZGA 1GFOA 3HOLA 3V8UA 2IWVA 2XG6A 4CTDA 2KXPA 2WVPA 3KZIO 4LSHA 5KAFO 4AYID 5G3AA 5JDPA 3A0BO 1S5LO 1HXXA 3POXA 3POUA 1T16A 2KDYA 2N2LA 1HXUA 1MPFA 1ORMA 1GFQA 1QJ9A 2XTQA 3AA7B 3KVDD 3PF1A 3SYBA 4F4BA 3BRYA 5EE2A 2XE3A 1ZHTA 3AAEB 5DL8A 4AUIA 4LSIA 2YPVA 4C4VA 1QJ8A 3A0HO 3AAAB 2R4OA 3LK3B 4FESA 2Y0LA 4UB8O 1H6S1 3LK2A 4FQEA 4RJWA 4UB6O 5ADXK 5T5FA 4AZLA 2ZFGA 4O3WA 2XE2A 4FOZA 1E54A 5E79O 4O3ZA 1IZNA 3SY9A 4QQ1A 1ZHXA 4RLCA 4AYNA 5DL7A 4FZLA 4AKMA 1ZHZA 3VE2A 1HXTA 2JMMA 2R4LA 2FGRA 4JCHA 3SZDA 3FYXA 3GP6A 4Z3TA 3NSGA 4O49A 2KZ7B 1ZHWA 2M07A 3DA4A 2WJRA 1Q9FA 3DA3A 2LHFA 3PGRA 4LSEA 4KR8A 4O4UA 4AYEC 2F1CX 3AA0B 3T0SA 4AYMC 4AYDC 1P4TA 3LK42 3UAQA 4AKRB 1YS5A 2R4NA 4E1TA 2WJQA 2XMXA 1OSMA 2XE5A 3LK3A 4FSOA 5KAIO 3VE1A 4GCSA 2Y7SA 3AA6B 3JCUO 4FRTA 2F1VA 1THQA 4GCPA 5G39A 2R88A 3AA1B 3NJTA 4RLBA 2XE1A 4B61A 4O3YA 4FT6A 5TISO 2IWWA 3T20A 2J4UP 2M06A 4N58A 4FZNA 3T24A 1BH3A 1QJPA 2AXTO 4LSFA 2O4VA 4FRXA 3SYSA 4FZMA 3LK41 4PJ0O 4D65A 1MM4A 2R89A 3AA0A 3PORA 3WU2O 3C5OA 4E1SA 4N59A 3PQSA 3PQUA 2QTKA 2W80C 4PR7A 3SZVA 3JTYA 4FUVA 2MHLA 3POQA 3AA7A 4GHBA 5GTHO 2KXPB 2ZLDA 3UU2A 2PORA 4KRAA 3AAEA 2N2MA 5G26A 5H2FO 2YNKA 3AAAA 2K4TA 4KR4A 4RL9A 4XNLA 2J1NA 3HOEA 3VZTX 3HW9A 4N74A 4JFBA 1Q9GA 3RBHA 5D5DA 3PGSA 2K0LA 3A2SX 3HWBA 5DL5A 3UPGA 5PRNA 3WI5A 1MM5A 1OPFA 2OMFA 3EMNX 4C00A 5FVNA 6PRNA 5IYUA 3VZWX 3WI4A 3VY9X 1IZNB 2KZ7A 2PRNA 3G7GA 1BXWA 4U9CA 2KC0A 3VY8X 2Y0HA 2R4PA 4C69X 4AFKA 5B5EO 2Y0KA 2MNHA 1GFPA 4G75A 3K19A 3SY7A 4AKRA 5B66O 3O0EA 7PRNA 5AFUL 2X9KA 5GTIO 2X27X 2FGQX 4FMSA 3AA6A 3DZMA 4K3CA 4G76A 1BT9A 2W81C 1GFNA 2GE4A 2LFUA 2ODJA 3AA1A 4IL6O 4K3BA 4O3XB 2F1TA 2XTRA 4RJXA 3BRZA 1GFMA 3BS0A 4GCQA 1PRNA 1T1LA 4C4VB 2ERVA 2Y2XA 3QRCA 4XNKA 5ADXL 1ZHYA 3LK2B
chains in the Genus database with same CATH topology
1G90A 3VZUX 3PRNA 4BUMX 4GF4A 4D5UA 4PUXA 5GV0A 4D64A 5DL6A 8PRNA 1PHOA 5AFUK 3QRAA 4FSPA 4O4XA 3TZGA 1GFOA 3HOLA 3V8UA 2XG6A 2KXPA 4AYID 4LSHA 5JDPA 1HXXA 3POXA 3POUA 2KDYA 2N2LA 1HXUA 2XTQA 1MPFA 1GFQA 1ORMA 1QJ9A 3AA7B 3KVDD 3SYBA 4F4BA 5EE2A 4AUIA 2XE3A 1ZHTA 3AAEB 5DL8A 4LSIA 2YPVA 1QJ8A 3AAAB 3LK3B 4FESA 2Y0LA 1H6S1 3LK2A 4RJWA 5ADXK 5T5FA 4AZLA 2ZFGA 4O3WA 2XE2A 4FOZA 1E54A 3SY9A 4O3ZA 1IZNA 4AYNA 4QQ1A 1ZHXA 4RLCA 5DL7A 4FZLA 4AKMA 1ZHZA 3VE2A 1HXTA 2JMMA 2FGRA 4JCHA 3SZDA 3FYXA 3GP6A 4Z3TA 3NSGA 4O49A 2KZ7B 1ZHWA 2M07A 3DA4A 3DA3A 1Q9FA 2LHFA 4LSEA 4O4UA 4KR8A 4AYEC 3AA0B 3T0SA 4AYMC 4AYDC 1P4TA 3LK42 3UAQA 4AKRB 1YS5A 4E1TA 2XMXA 1OSMA 2XE5A 3LK3A 4FSOA 3VE1A 4GCSA 2Y7SA 3AA6B 4FRTA 2F1VA 1THQA 4GCPA 3AA1B 4RLBA 2XE1A 4B61A 4O3YA 4FT6A 3T20A 2J4UP 2M06A 4N58A 4FZNA 3T24A 1BH3A 1QJPA 4LSFA 2O4VA 4FRXA 3SYSA 4FZMA 3LK41 4D65A 1MM4A 3AA0A 3PORA 3C5OA 4E1SA 4N59A 3PQSA 3PQUA 2QTKA 2W80C 3SZVA 3JTYA 4FUVA 2MHLA 3POQA 3AA7A 4GHBA 2KXPB 2ZLDA 3UU2A 2PORA 4KRAA 3AAEA 2N2MA 5G26A 2YNKA 3AAAA 2K4TA 4KR4A 4RL9A 4XNLA 2J1NA 3HOEA 3VZTX 3HW9A 4JFBA 1Q9GA 3RBHA 5D5DA 2K0LA 3A2SX 3HWBA 5DL5A 3UPGA 5PRNA 3WI5A 1MM5A 1OPFA 2OMFA 3EMNX 5FVNA 6PRNA 5IYUA 3VZWX 3WI4A 3VY9X 1IZNB 2KZ7A 2PRNA 3G7GA 1BXWA 4U9CA 2KC0A 3VY8X 2Y0HA 4C69X 4AFKA 2Y0KA 2MNHA 1GFPA 4G75A 3K19A 3SY7A 4AKRA 3O0EA 7PRNA 5AFUL 2X27X 2FGQX 4FMSA 3AA6A 4G76A 1BT9A 2W81C 1GFNA 2GE4A 2LFUA 2ODJA 3AA1A 4O3XB 2F1TA 2XTRA 4RJXA 1GFMA 4GCQA 1PRNA 2ERVA 2Y2XA 3QRCA 4XNKA 5ADXL 1ZHYA 3LK2B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VZU X;  3PRN A;  4BUM X;  4D5U A;  4D64 A;  5DL6 A;  8PRN A;  1PHO A;  4FSP A;  1GFO A;  2XG6 A;  4LSH A;  5JDP A;  1HXX A;  3POX A;  3POU A;  1HXU A;  1MPF A;  3SYB A;  1GFQ A;  4AUI A;  2XE3 A;  5DL8 A;  4LSI A;  2Y0L A;  1H6S 1;  4RJW A;  2ZFG A;  3SY9 A;  2XE2 A;  4FOZ A;  1E54 A;  5DL7 A;  1HXT A;  2FGR A;  3SZD A;  3FYX A;  3NSG A;  4LSE A;  4KR8 A;  3T0S A;  1OSM A;  2XE5 A;  4FSO A;  4GCS A;  4FRT A;  4GCP A;  2XE1 A;  4FT6 A;  3T20 A;  2J4U P;  3T24 A;  1BH3 A;  4LSF A;  2O4V A;  4FRX A;  3SYS A;  4D65 A;  3POR A;  3SZV A;  2QTK A;  3JTY A;  3POQ A;  2ZLD A;  3UU2 A;  2POR A;  4KRA A;  2K4T A;  4KR4 A;  3VZT X;  2J1N A;  3HW9 A;  4JFB A;  3A2S X;  3HWB A;  5DL5 A;  3UPG A;  5PRN A;  3WI5 A;  1OPF A;  2OMF A;  3EMN X;  5FVN A;  6PRN A;  3VZW X;  3WI4 A;  3VY9 X;  2PRN A;  3VY8 X;  2Y0H A;  4C69 X;  2Y0K A;  3SY7 A;  1GFP A;  3K19 A;  3O0E A;  7PRN A;  2FGQ X;  4FMS A;  1BT9 A;  1GFN A;  2ODJ A;  4RJX A;  1GFM A;  4GCQ A;  1PRN A;  2Y2X A; 
#chains in the Genus database with same CATH topology
 2R8A A;  3VZU X;  1G90 A;  3PRN A;  2JQY A;  4GF4 A;  5G38 A;  4BUM X;  4PUX A;  3PGU A;  4D5U A;  3DWO X;  4N75 A;  3DWN A;  4D64 A;  5GV0 A;  5DL6 A;  8PRN A;  1PHO A;  5AFU K;  3QRA A;  4FSP A;  4O4X A;  3TZG A;  1GFO A;  3HOL A;  3V8U A;  2IWV A;  2XG6 A;  4CTD A;  2KXP A;  2WVP A;  3KZI O;  4LSH A;  5KAF O;  4AYI D;  5G3A A;  5JDP A;  3A0B O;  1S5L O;  1HXX A;  3POX A;  3POU A;  1T16 A;  2KDY A;  2N2L A;  1HXU A;  1MPF A;  1ORM A;  1GFQ A;  1QJ9 A;  2XTQ A;  3AA7 B;  3KVD D;  3PF1 A;  3SYB A;  4F4B A;  3BRY A;  5EE2 A;  2XE3 A;  1ZHT A;  3AAE B;  5DL8 A;  4AUI A;  4LSI A;  2YPV A;  4C4V A;  1QJ8 A;  3A0H O;  3AAA B;  2R4O A;  3LK3 B;  4FES A;  2Y0L A;  4UB8 O;  1H6S 1;  3LK2 A;  4FQE A;  4RJW A;  4UB6 O;  5ADX K;  5T5F A;  4AZL A;  2ZFG A;  4O3W A;  2XE2 A;  4FOZ A;  1E54 A;  5E79 O;  4O3Z A;  1IZN A;  3SY9 A;  4QQ1 A;  1ZHX A;  4RLC A;  4AYN A;  5DL7 A;  4FZL A;  4AKM A;  1ZHZ A;  3VE2 A;  1HXT A;  2JMM A;  2R4L A;  2FGR A;  4JCH A;  3SZD A;  3FYX A;  3GP6 A;  4Z3T A;  3NSG A;  4O49 A;  2KZ7 B;  1ZHW A;  2M07 A;  3DA4 A;  2WJR A;  1Q9F A;  3DA3 A;  2LHF A;  3PGR A;  4LSE A;  4KR8 A;  4O4U A;  4AYE C;  2F1C X;  3AA0 B;  3T0S A;  4AYM C;  4AYD C;  1P4T A;  3LK4 2;  3UAQ A;  4AKR B;  1YS5 A;  2R4N A;  4E1T A;  2WJQ A;  2XMX A;  1OSM A;  2XE5 A;  3LK3 A;  4FSO A;  5KAI O;  3VE1 A;  4GCS A;  2Y7S A;  3AA6 B;  3JCU O;  4FRT A;  2F1V A;  1THQ A;  4GCP A;  5G39 A;  2R88 A;  3AA1 B;  3NJT A;  4RLB A;  2XE1 A;  4B61 A;  4O3Y A;  4FT6 A;  5TIS O;  2IWW A;  3T20 A;  2J4U P;  2M06 A;  4N58 A;  4FZN A;  3T24 A;  1BH3 A;  1QJP A;  2AXT O;  4LSF A;  2O4V A;  4FRX A;  3SYS A;  4FZM A;  3LK4 1;  4PJ0 O;  4D65 A;  1MM4 A;  2R89 A;  3AA0 A;  3POR A;  3WU2 O;  3C5O A;  4E1S A;  4N59 A;  3PQS A;  3PQU A;  2QTK A;  2W80 C;  4PR7 A;  3SZV A;  3JTY A;  4FUV A;  2MHL A;  3POQ A;  3AA7 A;  4GHB A;  5GTH O;  2KXP B;  2ZLD A;  3UU2 A;  2POR A;  4KRA A;  3AAE A;  2N2M A;  5G26 A;  5H2F O;  2YNK A;  3AAA A;  2K4T A;  4KR4 A;  4RL9 A;  4XNL A;  2J1N A;  3HOE A;  3VZT X;  3HW9 A;  4N74 A;  4JFB A;  1Q9G A;  3RBH A;  5D5D A;  3PGS A;  2K0L A;  3A2S X;  3HWB A;  5DL5 A;  3UPG A;  5PRN A;  3WI5 A;  1MM5 A;  1OPF A;  2OMF A;  3EMN X;  4C00 A;  5FVN A;  6PRN A;  5IYU A;  3VZW X;  3WI4 A;  3VY9 X;  1IZN B;  2KZ7 A;  2PRN A;  3G7G A;  1BXW A;  4U9C A;  2KC0 A;  3VY8 X;  2Y0H A;  2R4P A;  4C69 X;  4AFK A;  5B5E O;  2Y0K A;  2MNH A;  1GFP A;  4G75 A;  3K19 A;  3SY7 A;  4AKR A;  5B66 O;  3O0E A;  7PRN A;  5AFU L;  2X9K A;  5GTI O;  2X27 X;  2FGQ X;  4FMS A;  3AA6 A;  3DZM A;  4K3C A;  4G76 A;  1BT9 A;  2W81 C;  1GFN A;  2GE4 A;  2LFU A;  2ODJ A;  3AA1 A;  4IL6 O;  4K3B A;  4O3X B;  2F1T A;  2XTR A;  4RJX A;  3BRZ A;  1GFM A;  3BS0 A;  4GCQ A;  1PRN A;  1T1L A;  4C4V B;  2ERV A;  2Y2X A;  3QRC A;  4XNK A;  5ADX L;  1ZHY A;  3LK2 B; 
#chains in the Genus database with same CATH homology
 1G90 A;  3VZU X;  3PRN A;  4BUM X;  4GF4 A;  4D5U A;  4PUX A;  5GV0 A;  4D64 A;  5DL6 A;  8PRN A;  1PHO A;  5AFU K;  3QRA A;  4FSP A;  4O4X A;  3TZG A;  1GFO A;  3HOL A;  3V8U A;  2XG6 A;  2KXP A;  4AYI D;  4LSH A;  5JDP A;  1HXX A;  3POX A;  3POU A;  2KDY A;  2N2L A;  1HXU A;  2XTQ A;  1MPF A;  1GFQ A;  1ORM A;  1QJ9 A;  3AA7 B;  3KVD D;  3SYB A;  4F4B A;  5EE2 A;  4AUI A;  2XE3 A;  1ZHT A;  3AAE B;  5DL8 A;  4LSI A;  2YPV A;  1QJ8 A;  3AAA B;  3LK3 B;  4FES A;  2Y0L A;  1H6S 1;  3LK2 A;  4RJW A;  5ADX K;  5T5F A;  4AZL A;  2ZFG A;  4O3W A;  2XE2 A;  4FOZ A;  1E54 A;  3SY9 A;  4O3Z A;  1IZN A;  4AYN A;  4QQ1 A;  1ZHX A;  4RLC A;  5DL7 A;  4FZL A;  4AKM A;  1ZHZ A;  3VE2 A;  1HXT A;  2JMM A;  2FGR A;  4JCH A;  3SZD A;  3FYX A;  3GP6 A;  4Z3T A;  3NSG A;  4O49 A;  2KZ7 B;  1ZHW A;  2M07 A;  3DA4 A;  3DA3 A;  1Q9F A;  2LHF A;  4LSE A;  4O4U A;  4KR8 A;  4AYE C;  3AA0 B;  3T0S A;  4AYM C;  4AYD C;  1P4T A;  3LK4 2;  3UAQ A;  4AKR B;  1YS5 A;  4E1T A;  2XMX A;  1OSM A;  2XE5 A;  3LK3 A;  4FSO A;  3VE1 A;  4GCS A;  2Y7S A;  3AA6 B;  4FRT A;  2F1V A;  1THQ A;  4GCP A;  3AA1 B;  4RLB A;  2XE1 A;  4B61 A;  4O3Y A;  4FT6 A;  3T20 A;  2J4U P;  2M06 A;  4N58 A;  4FZN A;  3T24 A;  1BH3 A;  1QJP A;  4LSF A;  2O4V A;  4FRX A;  3SYS A;  4FZM A;  3LK4 1;  4D65 A;  1MM4 A;  3AA0 A;  3POR A;  3C5O A;  4E1S A;  4N59 A;  3PQS A;  3PQU A;  2QTK A;  2W80 C;  3SZV A;  3JTY A;  4FUV A;  2MHL A;  3POQ A;  3AA7 A;  4GHB A;  2KXP B;  2ZLD A;  3UU2 A;  2POR A;  4KRA A;  3AAE A;  2N2M A;  5G26 A;  2YNK A;  3AAA A;  2K4T A;  4KR4 A;  4RL9 A;  4XNL A;  2J1N A;  3HOE A;  3VZT X;  3HW9 A;  4JFB A;  1Q9G A;  3RBH A;  5D5D A;  2K0L A;  3A2S X;  3HWB A;  5DL5 A;  3UPG A;  5PRN A;  3WI5 A;  1MM5 A;  1OPF A;  2OMF A;  3EMN X;  5FVN A;  6PRN A;  5IYU A;  3VZW X;  3WI4 A;  3VY9 X;  1IZN B;  2KZ7 A;  2PRN A;  3G7G A;  1BXW A;  4U9C A;  2KC0 A;  3VY8 X;  2Y0H A;  4C69 X;  4AFK A;  2Y0K A;  2MNH A;  1GFP A;  4G75 A;  3K19 A;  3SY7 A;  4AKR A;  3O0E A;  7PRN A;  5AFU L;  2X27 X;  2FGQ X;  4FMS A;  3AA6 A;  4G76 A;  1BT9 A;  2W81 C;  1GFN A;  2GE4 A;  2LFU A;  2ODJ A;  3AA1 A;  4O3X B;  2F1T A;  2XTR A;  4RJX A;  1GFM A;  4GCQ A;  1PRN A;  2ERV A;  2Y2X A;  3QRC A;  4XNK A;  5ADX L;  1ZHY A;  3LK2 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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