2K4TA

Solution structure of human vdac-1 in ldao micelles
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
285
structure length
285
Chain Sequence
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQALE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.
pubmed doi rcsb
molecule tags Membrane protein,apoptosis
source organism Homo sapiens
molecule keywords Voltage-dependent anion-selective channel protein 1
total genus 43
structure length 285
sequence length 285
ec nomenclature
pdb deposition date 2008-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 2k4tA00
1GFQA 3PORA 4AUIA 3T0SA 4FT6A 3VY8X 3K19A 4FRXA 2FGQX 4LSFA 2OMFA 4FOZA 2XE2A 2Y2XA 5DL7A 2ZLDA 2PRNA 2XE3A 4KR8A 5PRNA 1GFPA 2J1NA 3UPGA 2XG6A 1OSMA 3POQA 1GFOA 3EMNX 4LSHA 2PORA 1PRNA 3SZDA 4RJXA 2Y0KA 3PRNA 2XE5A 4D64A 4FMSA 1PHOA 3UU2A 4RJWA 4GCQA 2FGRA 1GFMA 3SYSA 1MPFA 1HXUA 3SYBA 3JTYA 5DL5A 3SZVA 3POUA 3O0EA 3A2SX 3SY9A 1OPFA 3NSGA 5FVNA 4LSEA 3VZTX 4D5UA 7PRNA 1BH3A 4FSPA 3WI5A 4GCPA 3VZUX 4KRAA 3T24A 3HW9A 3FYXA 4C69X 1BT9A 3WI4A 3POXA 4GCSA 5DL6A 1HXXA 4D65A 4JFBA 2J4UP 2QTKA 3SY7A 5DL8A 2Y0HA 4LSIA 2Y0LA 3VY9X 4KR4A 4FSOA 2ODJA 1H6S1 1HXTA 2K4TA 3T20A 2O4VA 1E54A 4BUMX 2XE1A 1GFNA 8PRNA 3HWBA 6PRNA 5JDPA 4FRTA 3VZWX 2ZFGA
chains in the Genus database with same CATH superfamily
1GFQA 2R88A 4G75A 3PORA 5D5DA 5GTIO 2R89A 1ZHWA 4RLBA 4AUIA 3NJTA 2JQYA 3T0SA 4FT6A 3PF1A 3K19A 3VY8X 4O4XA 1ORMA 5B66O 4FRXA 2FGQX 4LSFA 1ZHZA 2OMFA 4FOZA 2XE2A 4N74A 2ERVA 2Y2XA 2IWWA 5DL7A 2ZLDA 4C00A 1P4TA 3AA7A 4AKMA 2PRNA 3AA0B 2XE3A 5G26A 4KR8A 4UB8O 5PRNA 1GFPA 3DA4A 4O4UA 2J1NA 3PGSA 3UPGA 2KC0A 5ADXL 2XG6A 2LFUA 3C5OA 1OSMA 2M07A 1Q9GA 2W81C 5AFUL 4IL6O 3HOEA 3AA6B 3KVDD 3POQA 3QRCA 1GFOA 4FZNA 3EMNX 4LSHA 2PORA 4AYMC 1IZNB 4PJ0O 3T24A 1PRNA 4GHBA 4E1TA 4O49A 5GTHO 3SZDA 2KDYA 4RJXA 2Y0KA 3PRNA 5B5EO 5G38A 2WVPA 2XE5A 3LK41 3PQSA 5KAIO 2R4PA 4FZLA 4O3XB 4FMSA 4RLCA 4FUVA 4D64A 4N59A 1PHOA 4XNLA 5G39A 4FESA 3LK42 5ADXK 3UU2A 4RJWA 3AAEA 2R4NA 3A0HO 4K3BA 4AYEC 4GCQA 3AA7B 4GF4A 2FGRA 5AFUK 1T16A 1GFMA 3AAAA 3SYSA 2XTQA 4AYNA 2XTRA 1MPFA 2XMXA 1HXUA 3SYBA 3JTYA 5DL5A 4E1SA 2F1VA 4O3ZA 4UB6O 2MHLA 3SZVA 2YNKA 3V8UA 3POUA 3O0EA 1MM5A 1YS5A 4FQEA 3A2SX 2K0LA 1S5LO 3G7GA 1OPFA 4K3CA 1T1LA 4N58A 4U9CA 3SY9A 3UAQA 2MNHA 3DWOX 3NSGA 4LSEA 3AA1A 5FVNA 3VZTX 4G76A 4D5UA 3BRYA 3DA3A 2KXPA 3RBHA 4CTDA 7PRNA 1BH3A 4FSPA 2KZ7A 2WJRA 3PQUA 3WI5A 3LK2B 3LK2A 4GCPA 3VZUX 1G90A 2Y7SA 4KRAA 2IWVA 1ZHTA 3HW9A 3LK3A 3AAEB 3FYXA 2F1CX 2R4OA 4RL9A 1Q9FA 3DWNA 4JCHA 5E79O 4C4VA 3BRZA 4AYID 2X9KA 4C69X 3AAAB 1BXWA 2AXTO 1BT9A 3BS0A 3WI4A 3POXA 3PGUA 4GCSA 4O3WA 3JCUO 5DL6A 2N2LA 5TISO 1HXXA 2LHFA 5H2FO 4XNKA 2R4LA 2N2MA 4JFBA 3TZGA 4D65A 2M06A 2QTKA 4PR7A 3SY7A 4Z3TA 2X27X 5DL8A 2J4UP 2Y0HA 3AA1B 4LSIA 2GE4A 1THQA 2Y0LA 3HOLA 3VY9X 4KR4A 4AZLA 2F1TA 2WJQA 2ODJA 3A0BO 2KXPB 1QJ8A 1ZHYA 4FSOA 4O3YA 4AKRA 4AKRB 2KZ7B 3VE2A 5GV0A 3KZIO 1H6S1 5EE2A 4FZMA 1HXTA 2K4TA 2W80C 3AA0A 3LK3B 4N75A 5G3AA 5KAFO 3VE1A 4AFKA 3T20A 4QQ1A 4AYDC 4C4VB 4F4BA 3DZMA 2JMMA 2O4VA 1ZHXA 3PGRA 3GP6A 2R8AA 1E54A 4B61A 4BUMX 2XE1A 3QRAA 5IYUA 1GFNA 8PRNA 3HWBA 6PRNA 5JDPA 3AA6A 1MM4A 4FRTA 3VZWX 4PUXA 3WU2O 2ZFGA 1QJ9A 2YPVA 1IZNA 5T5FA 1QJPA
chains in the Genus database with same CATH topology
1GFQA 4G75A 3PORA 5D5DA 1ZHWA 4RLBA 4AUIA 3T0SA 4FT6A 3VY8X 3K19A 4O4XA 1ORMA 4FRXA 2FGQX 4LSFA 1ZHZA 2OMFA 4FOZA 2XE2A 2ERVA 2Y2XA 5DL7A 2ZLDA 1P4TA 3AA7A 4AKMA 2PRNA 3AA0B 2XE3A 5G26A 4KR8A 5PRNA 1GFPA 3DA4A 4O4UA 2J1NA 3UPGA 2KC0A 5ADXL 2XG6A 2LFUA 3C5OA 1OSMA 2M07A 1Q9GA 2W81C 5AFUL 3HOEA 3AA6B 3KVDD 3POQA 3QRCA 1GFOA 4FZNA 3EMNX 4LSHA 2PORA 4AYMC 1IZNB 1PRNA 4GHBA 4E1TA 4O49A 3SZDA 2KDYA 4RJXA 2Y0KA 3PRNA 2XE5A 3LK41 3PQSA 4D64A 4FZLA 4O3XB 4FMSA 4RLCA 4FUVA 4N59A 1PHOA 4XNLA 4FESA 3LK42 5ADXK 3UU2A 4RJWA 3AAEA 4AYEC 4GCQA 3AA7B 4GF4A 2FGRA 5AFUK 1GFMA 3AAAA 3SYSA 2XTQA 4AYNA 2XTRA 1MPFA 2XMXA 1HXUA 3SYBA 3JTYA 5DL5A 4E1SA 2F1VA 4O3ZA 2MHLA 3SZVA 2YNKA 3V8UA 3POUA 3O0EA 1MM5A 1YS5A 3A2SX 2K0LA 3G7GA 4N58A 1OPFA 4U9CA 3SY9A 3UAQA 2MNHA 3NSGA 4LSEA 5FVNA 3AA1A 3VZTX 4G76A 4D5UA 3DA3A 2KXPA 3RBHA 7PRNA 1BH3A 4FSPA 2KZ7A 3PQUA 3WI5A 3LK2B 3LK2A 4GCPA 3VZUX 1G90A 2Y7SA 4KRAA 3LK3A 1ZHTA 3HW9A 4RL9A 3AAEB 3FYXA 3T24A 1Q9FA 4JCHA 4AYID 4C69X 3AAAB 1BXWA 1BT9A 3WI4A 3POXA 4GCSA 4O3WA 5DL6A 2N2LA 1HXXA 2LHFA 4XNKA 2N2MA 4JFBA 4D65A 3TZGA 2J4UP 2M06A 2QTKA 3SY7A 4Z3TA 2X27X 5DL8A 2Y0HA 3AA1B 4LSIA 2GE4A 1THQA 2Y0LA 3HOLA 3VY9X 4KR4A 4AZLA 2F1TA 4FSOA 2ODJA 2KXPB 1QJ8A 1ZHYA 4O3YA 4AKRA 4AKRB 2KZ7B 3VE2A 5GV0A 5EE2A 1H6S1 4FZMA 1HXTA 2K4TA 2W80C 3AA0A 3LK3B 4AFKA 3VE1A 3T20A 4QQ1A 4AYDC 4F4BA 2JMMA 2O4VA 1ZHXA 3GP6A 1E54A 4B61A 4BUMX 2XE1A 3QRAA 5IYUA 1GFNA 8PRNA 3HWBA 6PRNA 5JDPA 3AA6A 1MM4A 4FRTA 3VZWX 4PUXA 2ZFGA 1QJ9A 2YPVA 1IZNA 5T5FA 1QJPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GFQ A;  3POR A;  4AUI A;  3T0S A;  4FT6 A;  3VY8 X;  3K19 A;  4FRX A;  2FGQ X;  4LSF A;  2OMF A;  4FOZ A;  2XE2 A;  2Y2X A;  5DL7 A;  2ZLD A;  2PRN A;  2XE3 A;  4KR8 A;  5PRN A;  1GFP A;  2J1N A;  3UPG A;  2XG6 A;  1OSM A;  3POQ A;  1GFO A;  3EMN X;  4LSH A;  2POR A;  1PRN A;  3SZD A;  4RJX A;  2Y0K A;  3PRN A;  2XE5 A;  4D64 A;  4FMS A;  1PHO A;  3UU2 A;  4RJW A;  4GCQ A;  2FGR A;  1GFM A;  3SYS A;  1MPF A;  1HXU A;  3SYB A;  3JTY A;  5DL5 A;  3SZV A;  3POU A;  3O0E A;  3A2S X;  3SY9 A;  1OPF A;  3NSG A;  5FVN A;  4LSE A;  3VZT X;  4D5U A;  7PRN A;  1BH3 A;  4FSP A;  3WI5 A;  4GCP A;  3VZU X;  4KRA A;  3T24 A;  3HW9 A;  3FYX A;  4C69 X;  1BT9 A;  3WI4 A;  3POX A;  4GCS A;  5DL6 A;  1HXX A;  4D65 A;  4JFB A;  2J4U P;  2QTK A;  3SY7 A;  5DL8 A;  2Y0H A;  4LSI A;  2Y0L A;  3VY9 X;  4KR4 A;  4FSO A;  2ODJ A;  1H6S 1;  1HXT A;  2K4T A;  3T20 A;  2O4V A;  1E54 A;  4BUM X;  2XE1 A;  1GFN A;  8PRN A;  3HWB A;  6PRN A;  5JDP A;  4FRT A;  3VZW X;  2ZFG A; 
#chains in the Genus database with same CATH topology
 1GFQ A;  2R88 A;  4G75 A;  3POR A;  5D5D A;  5GTI O;  2R89 A;  1ZHW A;  4RLB A;  4AUI A;  3NJT A;  2JQY A;  3T0S A;  4FT6 A;  3PF1 A;  3K19 A;  3VY8 X;  4O4X A;  1ORM A;  5B66 O;  4FRX A;  2FGQ X;  4LSF A;  1ZHZ A;  2OMF A;  4FOZ A;  2XE2 A;  4N74 A;  2ERV A;  2Y2X A;  2IWW A;  5DL7 A;  2ZLD A;  4C00 A;  1P4T A;  3AA7 A;  4AKM A;  2PRN A;  3AA0 B;  2XE3 A;  5G26 A;  4KR8 A;  4UB8 O;  5PRN A;  1GFP A;  3DA4 A;  4O4U A;  2J1N A;  3PGS A;  3UPG A;  2KC0 A;  5ADX L;  2XG6 A;  2LFU A;  3C5O A;  1OSM A;  2M07 A;  1Q9G A;  2W81 C;  5AFU L;  4IL6 O;  3HOE A;  3AA6 B;  3KVD D;  3POQ A;  3QRC A;  1GFO A;  4FZN A;  3EMN X;  4LSH A;  2POR A;  4AYM C;  1IZN B;  4PJ0 O;  3T24 A;  1PRN A;  4GHB A;  4E1T A;  4O49 A;  5GTH O;  3SZD A;  2KDY A;  4RJX A;  2Y0K A;  3PRN A;  5B5E O;  5G38 A;  2WVP A;  2XE5 A;  3LK4 1;  3PQS A;  5KAI O;  2R4P A;  4FZL A;  4O3X B;  4FMS A;  4RLC A;  4FUV A;  4D64 A;  4N59 A;  1PHO A;  4XNL A;  5G39 A;  4FES A;  3LK4 2;  5ADX K;  3UU2 A;  4RJW A;  3AAE A;  2R4N A;  3A0H O;  4K3B A;  4AYE C;  4GCQ A;  3AA7 B;  4GF4 A;  2FGR A;  5AFU K;  1T16 A;  1GFM A;  3AAA A;  3SYS A;  2XTQ A;  4AYN A;  2XTR A;  1MPF A;  2XMX A;  1HXU A;  3SYB A;  3JTY A;  5DL5 A;  4E1S A;  2F1V A;  4O3Z A;  4UB6 O;  2MHL A;  3SZV A;  2YNK A;  3V8U A;  3POU A;  3O0E A;  1MM5 A;  1YS5 A;  4FQE A;  3A2S X;  2K0L A;  1S5L O;  3G7G A;  1OPF A;  4K3C A;  1T1L A;  4N58 A;  4U9C A;  3SY9 A;  3UAQ A;  2MNH A;  3DWO X;  3NSG A;  4LSE A;  3AA1 A;  5FVN A;  3VZT X;  4G76 A;  4D5U A;  3BRY A;  3DA3 A;  2KXP A;  3RBH A;  4CTD A;  7PRN A;  1BH3 A;  4FSP A;  2KZ7 A;  2WJR A;  3PQU A;  3WI5 A;  3LK2 B;  3LK2 A;  4GCP A;  3VZU X;  1G90 A;  2Y7S A;  4KRA A;  2IWV A;  1ZHT A;  3HW9 A;  3LK3 A;  3AAE B;  3FYX A;  2F1C X;  2R4O A;  4RL9 A;  1Q9F A;  3DWN A;  4JCH A;  5E79 O;  4C4V A;  3BRZ A;  4AYI D;  2X9K A;  4C69 X;  3AAA B;  1BXW A;  2AXT O;  1BT9 A;  3BS0 A;  3WI4 A;  3POX A;  3PGU A;  4GCS A;  4O3W A;  3JCU O;  5DL6 A;  2N2L A;  5TIS O;  1HXX A;  2LHF A;  5H2F O;  4XNK A;  2R4L A;  2N2M A;  4JFB A;  3TZG A;  4D65 A;  2M06 A;  2QTK A;  4PR7 A;  3SY7 A;  4Z3T A;  2X27 X;  5DL8 A;  2J4U P;  2Y0H A;  3AA1 B;  4LSI A;  2GE4 A;  1THQ A;  2Y0L A;  3HOL A;  3VY9 X;  4KR4 A;  4AZL A;  2F1T A;  2WJQ A;  2ODJ A;  3A0B O;  2KXP B;  1QJ8 A;  1ZHY A;  4FSO A;  4O3Y A;  4AKR A;  4AKR B;  2KZ7 B;  3VE2 A;  5GV0 A;  3KZI O;  1H6S 1;  5EE2 A;  4FZM A;  1HXT A;  2K4T A;  2W80 C;  3AA0 A;  3LK3 B;  4N75 A;  5G3A A;  5KAF O;  3VE1 A;  4AFK A;  3T20 A;  4QQ1 A;  4AYD C;  4C4V B;  4F4B A;  3DZM A;  2JMM A;  2O4V A;  1ZHX A;  3PGR A;  3GP6 A;  2R8A A;  1E54 A;  4B61 A;  4BUM X;  2XE1 A;  3QRA A;  5IYU A;  1GFN A;  8PRN A;  3HWB A;  6PRN A;  5JDP A;  3AA6 A;  1MM4 A;  4FRT A;  3VZW X;  4PUX A;  3WU2 O;  2ZFG A;  1QJ9 A;  2YPV A;  1IZN A;  5T5F A;  1QJP A; 
#chains in the Genus database with same CATH homology
 1GFQ A;  4G75 A;  3POR A;  5D5D A;  1ZHW A;  4RLB A;  4AUI A;  3T0S A;  4FT6 A;  3VY8 X;  3K19 A;  4O4X A;  1ORM A;  4FRX A;  2FGQ X;  4LSF A;  1ZHZ A;  2OMF A;  4FOZ A;  2XE2 A;  2ERV A;  2Y2X A;  5DL7 A;  2ZLD A;  1P4T A;  3AA7 A;  4AKM A;  2PRN A;  3AA0 B;  2XE3 A;  5G26 A;  4KR8 A;  5PRN A;  1GFP A;  3DA4 A;  4O4U A;  2J1N A;  3UPG A;  2KC0 A;  5ADX L;  2XG6 A;  2LFU A;  3C5O A;  1OSM A;  2M07 A;  1Q9G A;  2W81 C;  5AFU L;  3HOE A;  3AA6 B;  3KVD D;  3POQ A;  3QRC A;  1GFO A;  4FZN A;  3EMN X;  4LSH A;  2POR A;  4AYM C;  1IZN B;  1PRN A;  4GHB A;  4E1T A;  4O49 A;  3SZD A;  2KDY A;  4RJX A;  2Y0K A;  3PRN A;  2XE5 A;  3LK4 1;  3PQS A;  4D64 A;  4FZL A;  4O3X B;  4FMS A;  4RLC A;  4FUV A;  4N59 A;  1PHO A;  4XNL A;  4FES A;  3LK4 2;  5ADX K;  3UU2 A;  4RJW A;  3AAE A;  4AYE C;  4GCQ A;  3AA7 B;  4GF4 A;  2FGR A;  5AFU K;  1GFM A;  3AAA A;  3SYS A;  2XTQ A;  4AYN A;  2XTR A;  1MPF A;  2XMX A;  1HXU A;  3SYB A;  3JTY A;  5DL5 A;  4E1S A;  2F1V A;  4O3Z A;  2MHL A;  3SZV A;  2YNK A;  3V8U A;  3POU A;  3O0E A;  1MM5 A;  1YS5 A;  3A2S X;  2K0L A;  3G7G A;  4N58 A;  1OPF A;  4U9C A;  3SY9 A;  3UAQ A;  2MNH A;  3NSG A;  4LSE A;  5FVN A;  3AA1 A;  3VZT X;  4G76 A;  4D5U A;  3DA3 A;  2KXP A;  3RBH A;  7PRN A;  1BH3 A;  4FSP A;  2KZ7 A;  3PQU A;  3WI5 A;  3LK2 B;  3LK2 A;  4GCP A;  3VZU X;  1G90 A;  2Y7S A;  4KRA A;  3LK3 A;  1ZHT A;  3HW9 A;  4RL9 A;  3AAE B;  3FYX A;  3T24 A;  1Q9F A;  4JCH A;  4AYI D;  4C69 X;  3AAA B;  1BXW A;  1BT9 A;  3WI4 A;  3POX A;  4GCS A;  4O3W A;  5DL6 A;  2N2L A;  1HXX A;  2LHF A;  4XNK A;  2N2M A;  4JFB A;  4D65 A;  3TZG A;  2J4U P;  2M06 A;  2QTK A;  3SY7 A;  4Z3T A;  2X27 X;  5DL8 A;  2Y0H A;  3AA1 B;  4LSI A;  2GE4 A;  1THQ A;  2Y0L A;  3HOL A;  3VY9 X;  4KR4 A;  4AZL A;  2F1T A;  4FSO A;  2ODJ A;  2KXP B;  1QJ8 A;  1ZHY A;  4O3Y A;  4AKR A;  4AKR B;  2KZ7 B;  3VE2 A;  5GV0 A;  5EE2 A;  1H6S 1;  4FZM A;  1HXT A;  2K4T A;  2W80 C;  3AA0 A;  3LK3 B;  4AFK A;  3VE1 A;  3T20 A;  4QQ1 A;  4AYD C;  4F4B A;  2JMM A;  2O4V A;  1ZHX A;  3GP6 A;  1E54 A;  4B61 A;  4BUM X;  2XE1 A;  3QRA A;  5IYU A;  1GFN A;  8PRN A;  3HWB A;  6PRN A;  5JDP A;  3AA6 A;  1MM4 A;  4FRT A;  3VZW X;  4PUX A;  2ZFG A;  1QJ9 A;  2YPV A;  1IZN A;  5T5F A;  1QJP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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