2XE1A

Molecular insights into clinically isolated ompc mutants and their role in multi-drug resistance
Total Genus 105
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
354
structure length
354
Chain Sequence
AEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQIQGNAPESENNSWTRVAFAGLKFQDIGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGQNGSVSGENDPDFTGHGITNNGRKALRQNGDGVGGSITYDYEGFGVGAAVSSSKRTWDQNNTGLIGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVVAGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGLVYQF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords OUTER MEMBRANE PROTEIN C
total genus 105
structure length 354
sequence length 354
ec nomenclature
pdb deposition date 2010-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00267 Porin_1 Gram-negative porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 2xe1A00
3POQA 1HXTA 4AUIA 3VY9X 3SY9A 3SYBA 4FOZA 2Y0KA 3T20A 4RJXA 1BT9A 2K4TA 4FSOA 4FRXA 5DL6A 3UPGA 5FVNA 4LSHA 1E54A 1GFQA 2QTKA 4FRTA 4GCPA 2ZLDA 3UU2A 2FGQX 3JTYA 4KR4A 4FT6A 1H6S1 4JFBA 2XE2A 5JDPA 4LSFA 4GCSA 1PRNA 3O0EA 2Y2XA 2FGRA 2OMFA 3SYSA 3WI5A 5PRNA 4RJWA 3SY7A 4D64A 4LSIA 2PORA 1HXXA 3WI4A 4C69X 7PRNA 4LSEA 3PRNA 2PRNA 4BUMX 4KRAA 3VZWX 4D65A 1GFMA 3T24A 5DL8A 3FYXA 3VZUX 3HW9A 2ZFGA 2XE1A 1MPFA 3HWBA 2ODJA 5DL5A 2Y0LA 2XE5A 4D5UA 3NSGA 3POUA 1BH3A 3EMNX 3VY8X 1PHOA 3PORA 1GFPA 1OPFA 1OSMA 3T0SA 2J1NA 3POXA 1GFOA 3K19A 4FSPA 4KR8A 4FMSA 4GCQA 1GFNA 6PRNA 8PRNA 3A2SX 3VZTX 5DL7A 2O4VA 2Y0HA 2J4UP 2XE3A 1HXUA 3SZDA 2XG6A 3SZVA
chains in the Genus database with same CATH superfamily
4Z3TA 3PGUA 3POQA 3AA6B 1HXTA 4AUIA 3VY9X 3PGRA 3SY9A 3SYBA 4FOZA 4AYMC 2Y0KA 3DZMA 2X27X 4C00A 5B5EO 4U9CA 4F4BA 1G90A 3T20A 4RJXA 1BT9A 4G75A 2X9KA 4GF4A 1Q9FA 4CTDA 5GV0A 2K4TA 2JMMA 2XTQA 3DWNA 2N2LA 3QRCA 4FSOA 4FRXA 3RBHA 3C5OA 2KXPA 4B61A 1ORMA 5DL6A 3UPGA 5G26A 1ZHWA 2XMXA 3LK2B 5FVNA 3QRAA 4LSHA 1E54A 4FQEA 4C4VB 2R4PA 5G39A 4AYDC 4E1SA 1BXWA 4FESA 1MM4A 4K3BA 5AFUL 3AA1A 2R4LA 2R4NA 1GFQA 1T16A 5KAIO 2QTKA 4FRTA 2XTRA 3KVDD 2ZLDA 3LK3A 4GCPA 2F1CX 3A0BO 3UU2A 3AAAA 2FGQX 4E1TA 2WJRA 3JTYA 1P4TA 2AXTO 4KR4A 2WJQA 5IYUA 3DA3A 2R4OA 4FT6A 1H6S1 4O3XB 4JFBA 3V8UA 2XE2A 3BS0A 4IL6O 4RLBA 5JDPA 4AYEC 2F1TA 4LSFA 4GCSA 3PQUA 5GTIO 1PRNA 4O49A 1QJ8A 3O0EA 2Y2XA 2JQYA 1MM5A 3VE1A 2FGRA 2N2MA 2OMFA 3DWOX 3SYSA 1ZHXA 3VE2A 3WI5A 2KZ7A 5PRNA 4RJWA 4AYNA 5GTHO 2R8AA 3SY7A 4D64A 5ADXL 2LFUA 2MHLA 3HOEA 1IZNA 2PORA 4LSIA 4O3ZA 4UB8O 2KXPB 1HXXA 2W80C 3UAQA 3GP6A 3WI4A 3WU2O 3AA7A 4C69X 7PRNA 1IZNB 4LSEA 2W81C 5KAFO 3PRNA 2KDYA 2PRNA 3BRYA 4UB6O 5TISO 2WVPA 4BUMX 1THQA 4N74A 4AZLA 3AA1B 4FZNA 5H2FO 1Q9GA 2R88A 4FZMA 4KRAA 3DA4A 3LK3B 3VZWX 3AAAB 3NJTA 5EE2A 1S5LO 4FZLA 1GFMA 3PF1A 4N75A 4AKRA 4D65A 4N58A 3T24A 4PJ0O 4O4UA 3AAEA 2F1VA 3AA0A 3FYXA 5DL8A 1ZHTA 4RLCA 4XNLA 3VZUX 4AKRB 3AAEB 3HW9A 5AFUK 2ZFGA 2IWWA 2XE1A 2YPVA 1MPFA 3HWBA 2ERVA 5G3AA 2KZ7B 2ODJA 5DL5A 2KC0A 2LHFA 2Y0LA 3AA6A 3G7GA 4N59A 1ZHZA 4GHBA 2GE4A 1QJ9A 2XE5A 3JCUO 3AA7B 3LK41 4JCHA 5T5FA 4D5UA 5B66O 3NSGA 3LK42 3POUA 4O3YA 1BH3A 2MNHA 5D5DA 3EMNX 5E79O 4AYID 3VY8X 1PHOA 3PORA 4RL9A 4K3CA 2IWVA 4AFKA 5G38A 4XNKA 5ADXK 4PUXA 1GFPA 1YS5A 1OPFA 1OSMA 4PR7A 1T1LA 3LK2A 3T0SA 2J1NA 3POXA 3TZGA 2K0LA 1GFOA 1ZHYA 2Y7SA 3K19A 2M06A 3PQSA 4FSPA 4FUVA 4KR8A 4FMSA 2M07A 4GCQA 1GFNA 2YNKA 3AA0B 4O3WA 4QQ1A 4C4VA 6PRNA 3KZIO 8PRNA 3A2SX 3VZTX 2R89A 1QJPA 4O4XA 5DL7A 4G76A 2O4VA 3HOLA 3BRZA 4AKMA 2Y0HA 3PGSA 2J4UP 2XE3A 1HXUA 3SZDA 3A0HO 2XG6A 3SZVA
chains in the Genus database with same CATH topology
4Z3TA 3POQA 3AA6B 1HXTA 4AUIA 3VY9X 3SY9A 3SYBA 4FOZA 4AYMC 2Y0KA 2X27X 4U9CA 4F4BA 1G90A 3T20A 4RJXA 1BT9A 4G75A 4GF4A 1Q9FA 5GV0A 2XTQA 2JMMA 2K4TA 3QRCA 2N2LA 4FSOA 3RBHA 4FRXA 3C5OA 2KXPA 4B61A 1ORMA 5DL6A 3UPGA 5G26A 1ZHWA 2XMXA 3LK2B 5FVNA 3QRAA 4LSHA 1E54A 4AYDC 4E1SA 1BXWA 4FESA 1MM4A 5AFUL 3AA1A 1GFQA 2QTKA 4FRTA 2XTRA 3KVDD 2ZLDA 3LK3A 4GCPA 4E1TA 3UU2A 3AAAA 2FGQX 3JTYA 1P4TA 5IYUA 4KR4A 3DA3A 4FT6A 1H6S1 4O3XB 4JFBA 3V8UA 2XE2A 4RLBA 5JDPA 4AYEC 2F1TA 4LSFA 4GCSA 3PQUA 1PRNA 4O49A 1QJ8A 3O0EA 2Y2XA 3VE1A 1MM5A 2FGRA 2N2MA 2OMFA 3SYSA 1ZHXA 3VE2A 3WI5A 2KZ7A 5PRNA 4RJWA 4AYNA 3SY7A 5ADXL 4D64A 2LFUA 2MHLA 3HOEA 1IZNA 2PORA 4LSIA 4O3ZA 2KXPB 1HXXA 2W80C 3UAQA 3GP6A 3WI4A 4C69X 3AA7A 7PRNA 1IZNB 4LSEA 2W81C 3PRNA 2KDYA 2PRNA 4BUMX 1THQA 4AZLA 3AA1B 4FZNA 1Q9GA 4FZMA 4KRAA 3DA4A 3LK3B 3VZWX 3AAAB 5EE2A 4AKRA 4FZLA 4D65A 1GFMA 4N58A 3T24A 4O4UA 3AAEA 2F1VA 3AA0A 3FYXA 5DL8A 1ZHTA 4RLCA 4XNLA 3VZUX 4AKRB 3AAEB 3HW9A 5AFUK 2ZFGA 2XE1A 2YPVA 1MPFA 3HWBA 2ERVA 2KZ7B 2ODJA 5DL5A 2KC0A 2LHFA 2Y0LA 3AA6A 3G7GA 4N59A 1ZHZA 4GHBA 2GE4A 1QJ9A 2XE5A 3AA7B 3LK41 4JCHA 5T5FA 4D5UA 3NSGA 3LK42 3POUA 4O3YA 1BH3A 2MNHA 5D5DA 3EMNX 4AYID 3VY8X 1PHOA 3PORA 4RL9A 4AFKA 4XNKA 5ADXK 4PUXA 1GFPA 1YS5A 1OPFA 1OSMA 3LK2A 3T0SA 2J1NA 3POXA 3TZGA 2K0LA 1GFOA 1ZHYA 2Y7SA 3K19A 2M06A 3PQSA 4FSPA 4FUVA 4KR8A 4FMSA 2M07A 4GCQA 1GFNA 2YNKA 3AA0B 4O3WA 4QQ1A 6PRNA 8PRNA 3A2SX 3VZTX 4O4XA 1QJPA 5DL7A 4G76A 2O4VA 3HOLA 4AKMA 2Y0HA 2J4UP 2XE3A 1HXUA 3SZDA 2XG6A 3SZVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3POQ A;  1HXT A;  4AUI A;  3VY9 X;  3SY9 A;  3SYB A;  4FOZ A;  2Y0K A;  3T20 A;  4RJX A;  1BT9 A;  2K4T A;  4FSO A;  4FRX A;  5DL6 A;  3UPG A;  5FVN A;  4LSH A;  1E54 A;  1GFQ A;  2QTK A;  4FRT A;  4GCP A;  2ZLD A;  3UU2 A;  2FGQ X;  3JTY A;  4KR4 A;  4FT6 A;  1H6S 1;  4JFB A;  2XE2 A;  5JDP A;  4LSF A;  4GCS A;  1PRN A;  3O0E A;  2Y2X A;  2FGR A;  2OMF A;  3SYS A;  3WI5 A;  5PRN A;  4RJW A;  3SY7 A;  4D64 A;  4LSI A;  2POR A;  1HXX A;  3WI4 A;  4C69 X;  7PRN A;  4LSE A;  3PRN A;  2PRN A;  4BUM X;  4KRA A;  3VZW X;  4D65 A;  1GFM A;  3T24 A;  5DL8 A;  3FYX A;  3VZU X;  3HW9 A;  2ZFG A;  2XE1 A;  1MPF A;  3HWB A;  2ODJ A;  5DL5 A;  2Y0L A;  2XE5 A;  4D5U A;  3NSG A;  3POU A;  1BH3 A;  3EMN X;  3VY8 X;  1PHO A;  3POR A;  1GFP A;  1OPF A;  1OSM A;  3T0S A;  2J1N A;  3POX A;  1GFO A;  3K19 A;  4FSP A;  4KR8 A;  4FMS A;  4GCQ A;  1GFN A;  6PRN A;  8PRN A;  3A2S X;  3VZT X;  5DL7 A;  2O4V A;  2Y0H A;  2J4U P;  2XE3 A;  1HXU A;  3SZD A;  2XG6 A;  3SZV A; 
#chains in the Genus database with same CATH topology
 4Z3T A;  3PGU A;  3POQ A;  3AA6 B;  1HXT A;  4AUI A;  3VY9 X;  3PGR A;  3SY9 A;  3SYB A;  4FOZ A;  4AYM C;  2Y0K A;  3DZM A;  2X27 X;  4C00 A;  5B5E O;  4U9C A;  4F4B A;  1G90 A;  3T20 A;  4RJX A;  1BT9 A;  4G75 A;  2X9K A;  4GF4 A;  1Q9F A;  4CTD A;  5GV0 A;  2K4T A;  2JMM A;  2XTQ A;  3DWN A;  2N2L A;  3QRC A;  4FSO A;  4FRX A;  3RBH A;  3C5O A;  2KXP A;  4B61 A;  1ORM A;  5DL6 A;  3UPG A;  5G26 A;  1ZHW A;  2XMX A;  3LK2 B;  5FVN A;  3QRA A;  4LSH A;  1E54 A;  4FQE A;  4C4V B;  2R4P A;  5G39 A;  4AYD C;  4E1S A;  1BXW A;  4FES A;  1MM4 A;  4K3B A;  5AFU L;  3AA1 A;  2R4L A;  2R4N A;  1GFQ A;  1T16 A;  5KAI O;  2QTK A;  4FRT A;  2XTR A;  3KVD D;  2ZLD A;  3LK3 A;  4GCP A;  2F1C X;  3A0B O;  3UU2 A;  3AAA A;  2FGQ X;  4E1T A;  2WJR A;  3JTY A;  1P4T A;  2AXT O;  4KR4 A;  2WJQ A;  5IYU A;  3DA3 A;  2R4O A;  4FT6 A;  1H6S 1;  4O3X B;  4JFB A;  3V8U A;  2XE2 A;  3BS0 A;  4IL6 O;  4RLB A;  5JDP A;  4AYE C;  2F1T A;  4LSF A;  4GCS A;  3PQU A;  5GTI O;  1PRN A;  4O49 A;  1QJ8 A;  3O0E A;  2Y2X A;  2JQY A;  1MM5 A;  3VE1 A;  2FGR A;  2N2M A;  2OMF A;  3DWO X;  3SYS A;  1ZHX A;  3VE2 A;  3WI5 A;  2KZ7 A;  5PRN A;  4RJW A;  4AYN A;  5GTH O;  2R8A A;  3SY7 A;  4D64 A;  5ADX L;  2LFU A;  2MHL A;  3HOE A;  1IZN A;  2POR A;  4LSI A;  4O3Z A;  4UB8 O;  2KXP B;  1HXX A;  2W80 C;  3UAQ A;  3GP6 A;  3WI4 A;  3WU2 O;  3AA7 A;  4C69 X;  7PRN A;  1IZN B;  4LSE A;  2W81 C;  5KAF O;  3PRN A;  2KDY A;  2PRN A;  3BRY A;  4UB6 O;  5TIS O;  2WVP A;  4BUM X;  1THQ A;  4N74 A;  4AZL A;  3AA1 B;  4FZN A;  5H2F O;  1Q9G A;  2R88 A;  4FZM A;  4KRA A;  3DA4 A;  3LK3 B;  3VZW X;  3AAA B;  3NJT A;  5EE2 A;  1S5L O;  4FZL A;  1GFM A;  3PF1 A;  4N75 A;  4AKR A;  4D65 A;  4N58 A;  3T24 A;  4PJ0 O;  4O4U A;  3AAE A;  2F1V A;  3AA0 A;  3FYX A;  5DL8 A;  1ZHT A;  4RLC A;  4XNL A;  3VZU X;  4AKR B;  3AAE B;  3HW9 A;  5AFU K;  2ZFG A;  2IWW A;  2XE1 A;  2YPV A;  1MPF A;  3HWB A;  2ERV A;  5G3A A;  2KZ7 B;  2ODJ A;  5DL5 A;  2KC0 A;  2LHF A;  2Y0L A;  3AA6 A;  3G7G A;  4N59 A;  1ZHZ A;  4GHB A;  2GE4 A;  1QJ9 A;  2XE5 A;  3JCU O;  3AA7 B;  3LK4 1;  4JCH A;  5T5F A;  4D5U A;  5B66 O;  3NSG A;  3LK4 2;  3POU A;  4O3Y A;  1BH3 A;  2MNH A;  5D5D A;  3EMN X;  5E79 O;  4AYI D;  3VY8 X;  1PHO A;  3POR A;  4RL9 A;  4K3C A;  2IWV A;  4AFK A;  5G38 A;  4XNK A;  5ADX K;  4PUX A;  1GFP A;  1YS5 A;  1OPF A;  1OSM A;  4PR7 A;  1T1L A;  3LK2 A;  3T0S A;  2J1N A;  3POX A;  3TZG A;  2K0L A;  1GFO A;  1ZHY A;  2Y7S A;  3K19 A;  2M06 A;  3PQS A;  4FSP A;  4FUV A;  4KR8 A;  4FMS A;  2M07 A;  4GCQ A;  1GFN A;  2YNK A;  3AA0 B;  4O3W A;  4QQ1 A;  4C4V A;  6PRN A;  3KZI O;  8PRN A;  3A2S X;  3VZT X;  2R89 A;  1QJP A;  4O4X A;  5DL7 A;  4G76 A;  2O4V A;  3HOL A;  3BRZ A;  4AKM A;  2Y0H A;  3PGS A;  2J4U P;  2XE3 A;  1HXU A;  3SZD A;  3A0H O;  2XG6 A;  3SZV A; 
#chains in the Genus database with same CATH homology
 4Z3T A;  3POQ A;  3AA6 B;  1HXT A;  4AUI A;  3VY9 X;  3SY9 A;  3SYB A;  4FOZ A;  4AYM C;  2Y0K A;  2X27 X;  4U9C A;  4F4B A;  1G90 A;  3T20 A;  4RJX A;  1BT9 A;  4G75 A;  4GF4 A;  1Q9F A;  5GV0 A;  2XTQ A;  2JMM A;  2K4T A;  3QRC A;  2N2L A;  4FSO A;  3RBH A;  4FRX A;  3C5O A;  2KXP A;  4B61 A;  1ORM A;  5DL6 A;  3UPG A;  5G26 A;  1ZHW A;  2XMX A;  3LK2 B;  5FVN A;  3QRA A;  4LSH A;  1E54 A;  4AYD C;  4E1S A;  1BXW A;  4FES A;  1MM4 A;  5AFU L;  3AA1 A;  1GFQ A;  2QTK A;  4FRT A;  2XTR A;  3KVD D;  2ZLD A;  3LK3 A;  4GCP A;  4E1T A;  3UU2 A;  3AAA A;  2FGQ X;  3JTY A;  1P4T A;  5IYU A;  4KR4 A;  3DA3 A;  4FT6 A;  1H6S 1;  4O3X B;  4JFB A;  3V8U A;  2XE2 A;  4RLB A;  5JDP A;  4AYE C;  2F1T A;  4LSF A;  4GCS A;  3PQU A;  1PRN A;  4O49 A;  1QJ8 A;  3O0E A;  2Y2X A;  3VE1 A;  1MM5 A;  2FGR A;  2N2M A;  2OMF A;  3SYS A;  1ZHX A;  3VE2 A;  3WI5 A;  2KZ7 A;  5PRN A;  4RJW A;  4AYN A;  3SY7 A;  5ADX L;  4D64 A;  2LFU A;  2MHL A;  3HOE A;  1IZN A;  2POR A;  4LSI A;  4O3Z A;  2KXP B;  1HXX A;  2W80 C;  3UAQ A;  3GP6 A;  3WI4 A;  4C69 X;  3AA7 A;  7PRN A;  1IZN B;  4LSE A;  2W81 C;  3PRN A;  2KDY A;  2PRN A;  4BUM X;  1THQ A;  4AZL A;  3AA1 B;  4FZN A;  1Q9G A;  4FZM A;  4KRA A;  3DA4 A;  3LK3 B;  3VZW X;  3AAA B;  5EE2 A;  4AKR A;  4FZL A;  4D65 A;  1GFM A;  4N58 A;  3T24 A;  4O4U A;  3AAE A;  2F1V A;  3AA0 A;  3FYX A;  5DL8 A;  1ZHT A;  4RLC A;  4XNL A;  3VZU X;  4AKR B;  3AAE B;  3HW9 A;  5AFU K;  2ZFG A;  2XE1 A;  2YPV A;  1MPF A;  3HWB A;  2ERV A;  2KZ7 B;  2ODJ A;  5DL5 A;  2KC0 A;  2LHF A;  2Y0L A;  3AA6 A;  3G7G A;  4N59 A;  1ZHZ A;  4GHB A;  2GE4 A;  1QJ9 A;  2XE5 A;  3AA7 B;  3LK4 1;  4JCH A;  5T5F A;  4D5U A;  3NSG A;  3LK4 2;  3POU A;  4O3Y A;  1BH3 A;  2MNH A;  5D5D A;  3EMN X;  4AYI D;  3VY8 X;  1PHO A;  3POR A;  4RL9 A;  4AFK A;  4XNK A;  5ADX K;  4PUX A;  1GFP A;  1YS5 A;  1OPF A;  1OSM A;  3LK2 A;  3T0S A;  2J1N A;  3POX A;  3TZG A;  2K0L A;  1GFO A;  1ZHY A;  2Y7S A;  3K19 A;  2M06 A;  3PQS A;  4FSP A;  4FUV A;  4KR8 A;  4FMS A;  2M07 A;  4GCQ A;  1GFN A;  2YNK A;  3AA0 B;  4O3W A;  4QQ1 A;  6PRN A;  8PRN A;  3A2S X;  3VZT X;  4O4X A;  1QJP A;  5DL7 A;  4G76 A;  2O4V A;  3HOL A;  4AKM A;  2Y0H A;  2J4U P;  2XE3 A;  1HXU A;  3SZD A;  2XG6 A;  3SZV A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...