2XE5A

Molecular insights into clinically isolated ompc mutants and their role in multi-drug resistance (ompc26)
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
343
structure length
343
Chain Sequence
AEIYNKDGNKLDLYGKVEGLHYFSDNDSKDGDKTYMRLGFKGETQVTDQLTGYGQWEYQIQGNEPESDNSSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYDSDNFMQQRGNGFATYRNTDFFGLVDGLDFAVQYQGKNGSAHGEGMTTNGRDDVFEQNGDGVGGSITYNYEGFGIGAAVSSSKRTWDQNNTGLIGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNRFTRDAGINTDDIVALGLVYQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords OUTER MEMBRANE PORIN C
total genus 101
structure length 343
sequence length 343
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2010-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00267 Porin_1 Gram-negative porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 2xe5A00
1BH3A 1GFMA 2FGQX 4GCQA 1GFPA 2K4TA 2Y0LA 3EMNX 2QTKA 3VZUX 5JDPA 4LSHA 3VZTX 3SYSA 1GFOA 2J1NA 4FSOA 3VY9X 1HXXA 3HWBA 3HW9A 3PORA 4FRTA 5DL7A 3VY8X 4BUMX 1E54A 4D5UA 3POXA 3SZVA 1HXTA 2Y2XA 4LSFA 6PRNA 1OPFA 4LSIA 4FRXA 3POUA 2FGRA 3O0EA 2XE5A 5FVNA 2ODJA 2ZLDA 2PORA 3JTYA 7PRNA 2XE3A 3K19A 4FMSA 4KR8A 8PRNA 2ZFGA 4FOZA 1GFQA 4D64A 2Y0KA 2Y0HA 3UU2A 3FYXA 1H6S1 1MPFA 3POQA 4GCSA 5DL5A 3NSGA 4JFBA 4AUIA 1BT9A 4GCPA 3VZWX 4FT6A 3WI5A 2PRNA 3UPGA 4C69X 3T20A 2OMFA 5PRNA 1HXUA 5DL8A 4RJXA 3SZDA 2J4UP 3T0SA 4LSEA 1PHOA 2XE2A 3A2SX 1PRNA 3WI4A 3T24A 3SYBA 4D65A 1OSMA 4KRAA 1GFNA 2O4VA 4FSPA 2XE1A 4KR4A 5DL6A 4RJWA 3SY9A 3PRNA 3SY7A 2XG6A
chains in the Genus database with same CATH superfamily
1BH3A 1ZHYA 1GFMA 4IL6O 4O3WA 4UB6O 5B66O 4C00A 2F1CX 1YS5A 2R4OA 3AAEB 2X27X 2FGQX 4GCQA 1GFPA 2K4TA 1ZHTA 3DZMA 4AYNA 4AYEC 3DA4A 2Y0LA 3AA6A 4JCHA 2K0LA 3A0HO 5D5DA 3EMNX 4XNLA 5B5EO 2QTKA 3VZUX 1QJPA 3GP6A 4O4XA 4CTDA 1IZNB 1ZHZA 4B61A 2W80C 3DWNA 3AA1B 4G76A 1Q9FA 1ZHWA 3PGSA 4PUXA 4LSHA 2YPVA 2N2LA 2KC0A 1T16A 3SYSA 3VZTX 5GV0A 1GFOA 4RLCA 5H2FO 2J1NA 3LK3A 4FSOA 4N58A 3VY9X 4C4VA 3BS0A 1HXXA 2F1VA 3HWBA 3HW9A 3PORA 3QRCA 4FRTA 4O49A 4O3YA 3NJTA 5DL7A 3VY8X 5E79O 3TZGA 4BUMX 4AYMC 1E54A 4D5UA 4FUVA 1ORMA 3PQSA 3POXA 2GE4A 3SZVA 3AA7A 1HXTA 4AYDC 2Y2XA 5AFUK 2KXPB 4LSFA 2WJQA 2R4PA 2Y7SA 3LK2A 3PGRA 4N74A 6PRNA 1MM4A 4K3CA 1OPFA 4N59A 3AAAB 4LSIA 4AKRA 4FRXA 3POUA 1G90A 2FGRA 2JMMA 2N2MA 2XE5A 2WVPA 3O0EA 5FVNA 4UB8O 2ODJA 4E1TA 5ADXK 2YNKA 2ZLDA 2PORA 3JTYA 3AAEA 2KZ7B 2XE3A 3K19A 7PRNA 4FMSA 4KR8A 5G39A 5IYUA 4O3ZA 3VE1A 4C69X 3QRAA 8PRNA 2ZFGA 4FOZA 1GFQA 4O3XB 4FZMA 4D64A 2Y0KA 2Y0HA 1IZNA 3UU2A 4FZNA 3AA1A 2R8AA 3FYXA 1H6S1 2LHFA 1MPFA 3LK41 3POQA 4GCSA 4C4VB 5DL5A 3HOEA 3NSGA 3KVDD 4FESA 4Z3TA 4O4UA 3AA0B 2MNHA 4JFBA 3VE2A 4RL9A 4E1SA 2JQYA 3LK42 4AUIA 4XNKA 2IWWA 1P4TA 1BT9A 4F4BA 3DWOX 4U9CA 4GCPA 2R89A 5AFUL 4FZLA 3V8UA 5G26A 2R4LA 4FT6A 3VZWX 5KAIO 2IWVA 5KAFO 3WI5A 5GTIO 2PRNA 3UPGA 2AXTO 3G7GA 2XTRA 2OMFA 2KXPA 1HXUA 4N75A 5G38A 5PRNA 3C5OA 1BXWA 3RBHA 5DL8A 3UAQA 3AA6B 4RJXA 2XTQA 3AAAA 3SZDA 2F1TA 5ADXL 2J4UP 4FQEA 3T0SA 4LSEA 5JDPA 4AKMA 1PHOA 2XE2A 3PQUA 1QJ8A 3A2SX 1PRNA 1T1LA 2M06A 2R4NA 2KZ7A 2ERVA 5G3AA 4RLBA 1MM5A 3T24A 3WI4A 3WU2O 5T5FA 3T20A 3PGUA 4K3BA 2MHLA 3A0BO 2M07A 3LK3B 3SYBA 2LFUA 2XMXA 4D65A 1OSMA 3BRZA 2W81C 5TISO 4KRAA 4QQ1A 1GFNA 2KDYA 2O4VA 3BRYA 4FSPA 1THQA 1ZHXA 2R88A 2X9KA 2XE1A 4KR4A 1Q9GA 3HOLA 5DL6A 4AFKA 4AYID 4AZLA 5GTHO 3PF1A 4GF4A 4PJ0O 4RJWA 3AA7B 4G75A 5EE2A 3SY9A 1QJ9A 3PRNA 1S5LO 4PR7A 3LK2B 3SY7A 3DA3A 3AA0A 4AKRB 4GHBA 3JCUO 2WJRA 3KZIO 2XG6A
chains in the Genus database with same CATH topology
1BH3A 1ZHYA 1GFMA 4O3WA 1YS5A 3AAEB 2X27X 2FGQX 4GCQA 1GFPA 2K4TA 1ZHTA 4AYNA 4AYEC 3DA4A 2Y0LA 3AA6A 4JCHA 2K0LA 5D5DA 3EMNX 4XNLA 2QTKA 3VZUX 1QJPA 3GP6A 4O4XA 1IZNB 1ZHZA 4B61A 2W80C 3AA1B 4G76A 1Q9FA 1ZHWA 4PUXA 5JDPA 4LSHA 2YPVA 2N2LA 2KC0A 3VZTX 3SYSA 5GV0A 1GFOA 4RLCA 2J1NA 3LK3A 4FSOA 4N58A 3VY9X 1HXXA 2F1VA 3HWBA 3HW9A 3PORA 3QRCA 4FRTA 4O49A 4O3YA 5DL7A 3VY8X 3TZGA 4BUMX 4AYMC 1E54A 4D5UA 4FUVA 1ORMA 3PQSA 3POXA 2GE4A 3SZVA 3AA7A 1HXTA 4AYDC 2Y2XA 5AFUK 2KXPB 4LSFA 2Y7SA 3LK2A 6PRNA 1MM4A 4N59A 1OPFA 4AKRA 3AAAB 4LSIA 4FRXA 3POUA 1G90A 2FGRA 2JMMA 2N2MA 2XE5A 3O0EA 5FVNA 4E1TA 2ODJA 5ADXK 2YNKA 2ZLDA 2PORA 3JTYA 3AAEA 2KZ7B 2XE3A 3K19A 7PRNA 4FMSA 4KR8A 5IYUA 4O3ZA 3VE1A 8PRNA 3QRAA 2ZFGA 4FOZA 1GFQA 4O3XB 4FZMA 4D64A 2Y0KA 2Y0HA 1IZNA 3UU2A 4FZNA 3AA1A 3FYXA 1H6S1 2LHFA 1MPFA 3LK41 3POQA 4GCSA 5DL5A 3HOEA 3NSGA 3KVDD 4FESA 4Z3TA 4O4UA 3AA0B 2MNHA 4JFBA 3VE2A 4RL9A 4E1SA 3LK42 4AUIA 4XNKA 1P4TA 1BT9A 4F4BA 4U9CA 4GCPA 5AFUL 4FZLA 3V8UA 5G26A 4FT6A 3VZWX 3WI5A 2PRNA 3UPGA 3G7GA 2XTRA 2OMFA 2KXPA 1HXUA 5PRNA 3RBHA 4C69X 3C5OA 1BXWA 5DL8A 3UAQA 3AA6B 4RJXA 2XTQA 3AAAA 3SZDA 2F1TA 5ADXL 2J4UP 3T0SA 4LSEA 4AKMA 1PHOA 2XE2A 3PQUA 1QJ8A 3A2SX 1PRNA 2M06A 2KZ7A 2ERVA 3WI4A 4RLBA 1MM5A 3T24A 3T20A 5T5FA 2MHLA 3LK3B 2M07A 3SYBA 2LFUA 2XMXA 4D65A 1OSMA 2W81C 4KRAA 4QQ1A 1GFNA 2KDYA 2O4VA 4FSPA 1THQA 1ZHXA 2XE1A 4AFKA 4KR4A 5DL6A 1Q9GA 3HOLA 4AZLA 4AYID 4GF4A 4RJWA 3AA7B 4G75A 5EE2A 3SY9A 1QJ9A 3PRNA 3LK2B 3SY7A 3DA3A 3AA0A 4AKRB 4GHBA 2XG6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BH3 A;  1GFM A;  2FGQ X;  4GCQ A;  1GFP A;  2K4T A;  2Y0L A;  3EMN X;  2QTK A;  3VZU X;  5JDP A;  4LSH A;  3VZT X;  3SYS A;  1GFO A;  2J1N A;  4FSO A;  3VY9 X;  1HXX A;  3HWB A;  3HW9 A;  3POR A;  4FRT A;  5DL7 A;  3VY8 X;  4BUM X;  1E54 A;  4D5U A;  3POX A;  3SZV A;  1HXT A;  2Y2X A;  4LSF A;  6PRN A;  1OPF A;  4LSI A;  4FRX A;  3POU A;  2FGR A;  3O0E A;  2XE5 A;  5FVN A;  2ODJ A;  2ZLD A;  2POR A;  3JTY A;  7PRN A;  2XE3 A;  3K19 A;  4FMS A;  4KR8 A;  8PRN A;  2ZFG A;  4FOZ A;  1GFQ A;  4D64 A;  2Y0K A;  2Y0H A;  3UU2 A;  3FYX A;  1H6S 1;  1MPF A;  3POQ A;  4GCS A;  5DL5 A;  3NSG A;  4JFB A;  4AUI A;  1BT9 A;  4GCP A;  3VZW X;  4FT6 A;  3WI5 A;  2PRN A;  3UPG A;  4C69 X;  3T20 A;  2OMF A;  5PRN A;  1HXU A;  5DL8 A;  4RJX A;  3SZD A;  2J4U P;  3T0S A;  4LSE A;  1PHO A;  2XE2 A;  3A2S X;  1PRN A;  3WI4 A;  3T24 A;  3SYB A;  4D65 A;  1OSM A;  4KRA A;  1GFN A;  2O4V A;  4FSP A;  2XE1 A;  4KR4 A;  5DL6 A;  4RJW A;  3SY9 A;  3PRN A;  3SY7 A;  2XG6 A; 
#chains in the Genus database with same CATH topology
 1BH3 A;  1ZHY A;  1GFM A;  4IL6 O;  4O3W A;  4UB6 O;  5B66 O;  4C00 A;  2F1C X;  1YS5 A;  2R4O A;  3AAE B;  2X27 X;  2FGQ X;  4GCQ A;  1GFP A;  2K4T A;  1ZHT A;  3DZM A;  4AYN A;  4AYE C;  3DA4 A;  2Y0L A;  3AA6 A;  4JCH A;  2K0L A;  3A0H O;  5D5D A;  3EMN X;  4XNL A;  5B5E O;  2QTK A;  3VZU X;  1QJP A;  3GP6 A;  4O4X A;  4CTD A;  1IZN B;  1ZHZ A;  4B61 A;  2W80 C;  3DWN A;  3AA1 B;  4G76 A;  1Q9F A;  1ZHW A;  3PGS A;  4PUX A;  4LSH A;  2YPV A;  2N2L A;  2KC0 A;  1T16 A;  3SYS A;  3VZT X;  5GV0 A;  1GFO A;  4RLC A;  5H2F O;  2J1N A;  3LK3 A;  4FSO A;  4N58 A;  3VY9 X;  4C4V A;  3BS0 A;  1HXX A;  2F1V A;  3HWB A;  3HW9 A;  3POR A;  3QRC A;  4FRT A;  4O49 A;  4O3Y A;  3NJT A;  5DL7 A;  3VY8 X;  5E79 O;  3TZG A;  4BUM X;  4AYM C;  1E54 A;  4D5U A;  4FUV A;  1ORM A;  3PQS A;  3POX A;  2GE4 A;  3SZV A;  3AA7 A;  1HXT A;  4AYD C;  2Y2X A;  5AFU K;  2KXP B;  4LSF A;  2WJQ A;  2R4P A;  2Y7S A;  3LK2 A;  3PGR A;  4N74 A;  6PRN A;  1MM4 A;  4K3C A;  1OPF A;  4N59 A;  3AAA B;  4LSI A;  4AKR A;  4FRX A;  3POU A;  1G90 A;  2FGR A;  2JMM A;  2N2M A;  2XE5 A;  2WVP A;  3O0E A;  5FVN A;  4UB8 O;  2ODJ A;  4E1T A;  5ADX K;  2YNK A;  2ZLD A;  2POR A;  3JTY A;  3AAE A;  2KZ7 B;  2XE3 A;  3K19 A;  7PRN A;  4FMS A;  4KR8 A;  5G39 A;  5IYU A;  4O3Z A;  3VE1 A;  4C69 X;  3QRA A;  8PRN A;  2ZFG A;  4FOZ A;  1GFQ A;  4O3X B;  4FZM A;  4D64 A;  2Y0K A;  2Y0H A;  1IZN A;  3UU2 A;  4FZN A;  3AA1 A;  2R8A A;  3FYX A;  1H6S 1;  2LHF A;  1MPF A;  3LK4 1;  3POQ A;  4GCS A;  4C4V B;  5DL5 A;  3HOE A;  3NSG A;  3KVD D;  4FES A;  4Z3T A;  4O4U A;  3AA0 B;  2MNH A;  4JFB A;  3VE2 A;  4RL9 A;  4E1S A;  2JQY A;  3LK4 2;  4AUI A;  4XNK A;  2IWW A;  1P4T A;  1BT9 A;  4F4B A;  3DWO X;  4U9C A;  4GCP A;  2R89 A;  5AFU L;  4FZL A;  3V8U A;  5G26 A;  2R4L A;  4FT6 A;  3VZW X;  5KAI O;  2IWV A;  5KAF O;  3WI5 A;  5GTI O;  2PRN A;  3UPG A;  2AXT O;  3G7G A;  2XTR A;  2OMF A;  2KXP A;  1HXU A;  4N75 A;  5G38 A;  5PRN A;  3C5O A;  1BXW A;  3RBH A;  5DL8 A;  3UAQ A;  3AA6 B;  4RJX A;  2XTQ A;  3AAA A;  3SZD A;  2F1T A;  5ADX L;  2J4U P;  4FQE A;  3T0S A;  4LSE A;  5JDP A;  4AKM A;  1PHO A;  2XE2 A;  3PQU A;  1QJ8 A;  3A2S X;  1PRN A;  1T1L A;  2M06 A;  2R4N A;  2KZ7 A;  2ERV A;  5G3A A;  4RLB A;  1MM5 A;  3T24 A;  3WI4 A;  3WU2 O;  5T5F A;  3T20 A;  3PGU A;  4K3B A;  2MHL A;  3A0B O;  2M07 A;  3LK3 B;  3SYB A;  2LFU A;  2XMX A;  4D65 A;  1OSM A;  3BRZ A;  2W81 C;  5TIS O;  4KRA A;  4QQ1 A;  1GFN A;  2KDY A;  2O4V A;  3BRY A;  4FSP A;  1THQ A;  1ZHX A;  2R88 A;  2X9K A;  2XE1 A;  4KR4 A;  1Q9G A;  3HOL A;  5DL6 A;  4AFK A;  4AYI D;  4AZL A;  5GTH O;  3PF1 A;  4GF4 A;  4PJ0 O;  4RJW A;  3AA7 B;  4G75 A;  5EE2 A;  3SY9 A;  1QJ9 A;  3PRN A;  1S5L O;  4PR7 A;  3LK2 B;  3SY7 A;  3DA3 A;  3AA0 A;  4AKR B;  4GHB A;  3JCU O;  2WJR A;  3KZI O;  2XG6 A; 
#chains in the Genus database with same CATH homology
 1BH3 A;  1ZHY A;  1GFM A;  4O3W A;  1YS5 A;  3AAE B;  2X27 X;  2FGQ X;  4GCQ A;  1GFP A;  2K4T A;  1ZHT A;  4AYN A;  4AYE C;  3DA4 A;  2Y0L A;  3AA6 A;  4JCH A;  2K0L A;  5D5D A;  3EMN X;  4XNL A;  2QTK A;  3VZU X;  1QJP A;  3GP6 A;  4O4X A;  1IZN B;  1ZHZ A;  4B61 A;  2W80 C;  3AA1 B;  4G76 A;  1Q9F A;  1ZHW A;  4PUX A;  5JDP A;  4LSH A;  2YPV A;  2N2L A;  2KC0 A;  3VZT X;  3SYS A;  5GV0 A;  1GFO A;  4RLC A;  2J1N A;  3LK3 A;  4FSO A;  4N58 A;  3VY9 X;  1HXX A;  2F1V A;  3HWB A;  3HW9 A;  3POR A;  3QRC A;  4FRT A;  4O49 A;  4O3Y A;  5DL7 A;  3VY8 X;  3TZG A;  4BUM X;  4AYM C;  1E54 A;  4D5U A;  4FUV A;  1ORM A;  3PQS A;  3POX A;  2GE4 A;  3SZV A;  3AA7 A;  1HXT A;  4AYD C;  2Y2X A;  5AFU K;  2KXP B;  4LSF A;  2Y7S A;  3LK2 A;  6PRN A;  1MM4 A;  4N59 A;  1OPF A;  4AKR A;  3AAA B;  4LSI A;  4FRX A;  3POU A;  1G90 A;  2FGR A;  2JMM A;  2N2M A;  2XE5 A;  3O0E A;  5FVN A;  4E1T A;  2ODJ A;  5ADX K;  2YNK A;  2ZLD A;  2POR A;  3JTY A;  3AAE A;  2KZ7 B;  2XE3 A;  3K19 A;  7PRN A;  4FMS A;  4KR8 A;  5IYU A;  4O3Z A;  3VE1 A;  8PRN A;  3QRA A;  2ZFG A;  4FOZ A;  1GFQ A;  4O3X B;  4FZM A;  4D64 A;  2Y0K A;  2Y0H A;  1IZN A;  3UU2 A;  4FZN A;  3AA1 A;  3FYX A;  1H6S 1;  2LHF A;  1MPF A;  3LK4 1;  3POQ A;  4GCS A;  5DL5 A;  3HOE A;  3NSG A;  3KVD D;  4FES A;  4Z3T A;  4O4U A;  3AA0 B;  2MNH A;  4JFB A;  3VE2 A;  4RL9 A;  4E1S A;  3LK4 2;  4AUI A;  4XNK A;  1P4T A;  1BT9 A;  4F4B A;  4U9C A;  4GCP A;  5AFU L;  4FZL A;  3V8U A;  5G26 A;  4FT6 A;  3VZW X;  3WI5 A;  2PRN A;  3UPG A;  3G7G A;  2XTR A;  2OMF A;  2KXP A;  1HXU A;  5PRN A;  3RBH A;  4C69 X;  3C5O A;  1BXW A;  5DL8 A;  3UAQ A;  3AA6 B;  4RJX A;  2XTQ A;  3AAA A;  3SZD A;  2F1T A;  5ADX L;  2J4U P;  3T0S A;  4LSE A;  4AKM A;  1PHO A;  2XE2 A;  3PQU A;  1QJ8 A;  3A2S X;  1PRN A;  2M06 A;  2KZ7 A;  2ERV A;  3WI4 A;  4RLB A;  1MM5 A;  3T24 A;  3T20 A;  5T5F A;  2MHL A;  3LK3 B;  2M07 A;  3SYB A;  2LFU A;  2XMX A;  4D65 A;  1OSM A;  2W81 C;  4KRA A;  4QQ1 A;  1GFN A;  2KDY A;  2O4V A;  4FSP A;  1THQ A;  1ZHX A;  2XE1 A;  4AFK A;  4KR4 A;  5DL6 A;  1Q9G A;  3HOL A;  4AZL A;  4AYI D;  4GF4 A;  4RJW A;  3AA7 B;  4G75 A;  5EE2 A;  3SY9 A;  1QJ9 A;  3PRN A;  3LK2 B;  3SY7 A;  3DA3 A;  3AA0 A;  4AKR B;  4GHB A;  2XG6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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