3EMNX

The crystal structure of mouse vdac1 at 2.3 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
283
structure length
283
Chain Sequence
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating
pubmed doi rcsb
molecule tags Membrane protein
source organism Mus musculus
molecule keywords Voltage-dependent anion-selective channel protein 1
total genus 63
structure length 283
sequence length 283
ec nomenclature
pdb deposition date 2008-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 3emnX00
2XE2A 3SZVA 3SYSA 4GCQA 2QTKA 3SY9A 3HWBA 3T0SA 2XG6A 3O0EA 3T20A 1GFPA 4GCPA 3PORA 1BT9A 1GFQA 3K19A 3JTYA 1GFNA 4FRXA 3WI5A 1HXTA 3A2SX 4GCSA 4LSFA 4RJXA 2XE3A 4LSEA 4FT6A 1PRNA 3VZWX 4FOZA 4JFBA 3VY8X 2XE1A 2Y2XA 1HXUA 7PRNA 4FSOA 2ODJA 4KR8A 8PRNA 3SZDA 2PORA 4KR4A 3T24A 3UPGA 2ZFGA 5DL5A 3EMNX 1GFMA 5PRNA 3POXA 3SYBA 4FSPA 2FGRA 4RJWA 4D65A 2OMFA 1E54A 2Y0LA 2J1NA 3HW9A 1MPFA 3POQA 2ZLDA 3UU2A 2XE5A 4D64A 2PRNA 1PHOA 1H6S1 4D5UA 3FYXA 4AUIA 1HXXA 3VZUX 5DL7A 3VY9X 4BUMX 3VZTX 5JDPA 4FRTA 4KRAA 4LSIA 6PRNA 1BH3A 3SY7A 1GFOA 2K4TA 3PRNA 1OPFA 4C69X 2O4VA 4FMSA 5DL6A 3NSGA 2Y0HA 3POUA 3WI4A 2FGQX 5DL8A 2Y0KA 4LSHA 5FVNA 2J4UP 1OSMA
chains in the Genus database with same CATH superfamily
2W80C 4AKRB 2XE2A 4JCHA 4FZNA 1ZHYA 3SZVA 3SYSA 4GCQA 4PR7A 3PGUA 2QTKA 1IZNA 4UB8O 3PQUA 3SY9A 2F1CX 3AA0B 3HWBA 3QRAA 1QJ9A 3T0SA 4O4XA 4IL6O 2KZ7B 3AA7A 4AKMA 2XG6A 3DWOX 2M06A 3DA4A 3O0EA 3T20A 5D5DA 1GFPA 4GCPA 3PORA 4AZLA 2WJRA 3AA1B 5ADXL 1QJPA 1BT9A 1GFQA 2AXTO 2XTRA 3K19A 4RLBA 3C5OA 3JTYA 4B61A 1GFNA 4FRXA 5EE2A 3RBHA 3WI5A 3BRZA 1ZHXA 2F1VA 1HXTA 2R4LA 3A2SX 4GCSA 3AAAB 4LSFA 2XE3A 4RJXA 1YS5A 1PRNA 4FT6A 3GP6A 4LSEA 5KAIO 3UAQA 3VZWX 4FOZA 4JFBA 3VY8X 4AKRA 2XE1A 2Y2XA 4N58A 3WU2O 2R4NA 5AFUK 2ERVA 4FQEA 1HXUA 2X27X 3AA0A 4G76A 7PRNA 2MNHA 2IWVA 2ODJA 4FSOA 4KR8A 2K0LA 2KZ7A 2F1TA 3AA6B 4AYNA 2LHFA 8PRNA 3SZDA 4AYEC 2PORA 3JCUO 3LK3B 1S5LO 4KR4A 4FESA 3T24A 1BXWA 3UPGA 3TZGA 2ZFGA 5DL5A 3EMNX 3A0HO 1GFMA 3AA1A 4XNLA 2MHLA 3KVDD 4AYMC 4FZLA 2JQYA 3PQSA 3POXA 5PRNA 3SYBA 2XTQA 3LK41 5T5FA 3DA3A 2YNKA 4FSPA 2FGRA 1T1LA 3LK2B 2R4OA 5ADXK 2KDYA 2W81C 3AAAA 4RJWA 2OMFA 5GTIO 4D65A 1E54A 3VE2A 2Y0LA 5G26A 2J1NA 1Q9GA 1QJ8A 3HW9A 2KXPB 1MPFA 3HOLA 3POQA 3DWNA 2KC0A 4G75A 4N74A 2N2LA 2R89A 4AFKA 4E1TA 5B66O 4O49A 2ZLDA 1T16A 5TISO 3UU2A 2XE5A 1ZHWA 3AA6A 5G39A 4D64A 1P4TA 2GE4A 3AAEB 2PRNA 2R8AA 3LK3A 4O3WA 1PHOA 1H6S1 4D5UA 4F4BA 2WJQA 2XMXA 3FYXA 4XNKA 5G38A 4AUIA 2X9KA 5KAFO 1HXXA 2IWWA 1THQA 3VZUX 5DL7A 4C4VB 3VY9X 4GHBA 4K3CA 1ORMA 4QQ1A 4BUMX 5AFUL 3VZTX 5JDPA 4O3YA 3LK2A 1ZHTA 3DZMA 2YPVA 4FRTA 4KRAA 4LSIA 2JMMA 4N75A 3A0BO 4UB6O 4AYDC 3KZIO 6PRNA 2N2MA 4FUVA 1BH3A 2LFUA 3G7GA 5GTHO 4N59A 4RLCA 1Q9FA 3SY7A 1GFOA 1IZNB 2K4TA 3PRNA 2KXPA 4PUXA 3V8UA 4U9CA 4C00A 4K3BA 3PGSA 1OPFA 3AA7B 4Z3TA 2R88A 5G3AA 3HOEA 4O3XB 2R4PA 2Y7SA 5E79O 4C69X 4PJ0O 1ZHZA 3AAEA 2O4VA 3QRCA 4FMSA 4FZMA 5DL6A 3NJTA 4E1SA 3BS0A 4AYID 3LK42 3NSGA 4O3ZA 2Y0HA 3POUA 5B5EO 1G90A 3PGRA 3WI4A 2FGQX 2M07A 5DL8A 3VE1A 5IYUA 4RL9A 1MM5A 3PF1A 5H2FO 2Y0KA 1MM4A 4LSHA 2WVPA 5FVNA 4C4VA 2J4UP 4GF4A 4CTDA 3BRYA 5GV0A 4O4UA 1OSMA
chains in the Genus database with same CATH topology
2W80C 4AKRB 2XE2A 4JCHA 4FZNA 1ZHYA 3SZVA 3SYSA 4GCQA 2QTKA 1IZNA 3SY9A 3PQUA 3AA0B 3HWBA 3QRAA 1QJ9A 3T0SA 4O4XA 4AKMA 2KZ7B 3AA7A 2XG6A 2M06A 3DA4A 3O0EA 3T20A 5D5DA 1GFPA 4GCPA 3PORA 4AZLA 3AA1B 5ADXL 1QJPA 1BT9A 1GFQA 2XTRA 3K19A 4RLBA 3C5OA 3JTYA 4B61A 1GFNA 4FRXA 5EE2A 3RBHA 3WI5A 1ZHXA 2F1VA 1HXTA 3A2SX 4GCSA 3AAAB 4LSFA 2XE3A 4RJXA 1YS5A 1PRNA 4FT6A 3GP6A 4LSEA 3UAQA 3VZWX 4FOZA 4JFBA 3VY8X 4AKRA 2XE1A 2Y2XA 4N58A 5AFUK 2ERVA 1HXUA 2X27X 3AA0A 4G76A 7PRNA 2MNHA 4FSOA 2ODJA 4KR8A 2K0LA 2KZ7A 2F1TA 3AA6B 4AYNA 2LHFA 8PRNA 3SZDA 4AYEC 2PORA 3LK3B 4KR4A 4FESA 3T24A 1BXWA 3UPGA 3TZGA 2ZFGA 5DL5A 3EMNX 1GFMA 3AA1A 4XNLA 2MHLA 3KVDD 4AYMC 4FZLA 3PQSA 5PRNA 3POXA 3SYBA 2XTQA 3LK41 5T5FA 3DA3A 2YNKA 4FSPA 2FGRA 3LK2B 5ADXK 2W81C 2KDYA 3AAAA 4RJWA 2OMFA 4D65A 1E54A 3VE2A 2Y0LA 5G26A 2J1NA 1Q9GA 1QJ8A 3HW9A 2KXPB 1MPFA 3HOLA 3POQA 2KC0A 4G75A 2N2LA 4AFKA 4E1TA 4O49A 2ZLDA 3UU2A 2XE5A 1ZHWA 3AA6A 4D64A 1P4TA 2GE4A 3AAEB 2PRNA 3LK3A 4O3WA 1PHOA 1H6S1 4D5UA 4F4BA 2XMXA 3FYXA 4XNKA 4AUIA 1HXXA 1THQA 3VZUX 5DL7A 3VY9X 4GHBA 1ORMA 4QQ1A 4BUMX 5AFUL 3VZTX 5JDPA 4O3YA 3LK2A 1ZHTA 2YPVA 4FRTA 4KRAA 4LSIA 2JMMA 4AYDC 6PRNA 2N2MA 4FUVA 1BH3A 2LFUA 3G7GA 4N59A 4RLCA 1Q9FA 3SY7A 1GFOA 1IZNB 2K4TA 3PRNA 2KXPA 4PUXA 3V8UA 4U9CA 1OPFA 3AA7B 4Z3TA 3HOEA 4O3XB 2Y7SA 4C69X 1ZHZA 3AAEA 2O4VA 3QRCA 4FMSA 4FZMA 5DL6A 4E1SA 4AYID 3LK42 3NSGA 4O3ZA 2Y0HA 3POUA 1G90A 3WI4A 2FGQX 2M07A 5DL8A 3VE1A 5IYUA 4RL9A 1MM5A 2Y0KA 1MM4A 4LSHA 5FVNA 2J4UP 4GF4A 5GV0A 4O4UA 1OSMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XE2 A;  3SZV A;  3SYS A;  4GCQ A;  2QTK A;  3SY9 A;  3HWB A;  3T0S A;  2XG6 A;  3O0E A;  3T20 A;  1GFP A;  4GCP A;  3POR A;  1BT9 A;  1GFQ A;  3K19 A;  3JTY A;  1GFN A;  4FRX A;  3WI5 A;  1HXT A;  3A2S X;  4GCS A;  4LSF A;  4RJX A;  2XE3 A;  4LSE A;  4FT6 A;  1PRN A;  3VZW X;  4FOZ A;  4JFB A;  3VY8 X;  2XE1 A;  2Y2X A;  1HXU A;  7PRN A;  4FSO A;  2ODJ A;  4KR8 A;  8PRN A;  3SZD A;  2POR A;  4KR4 A;  3T24 A;  3UPG A;  2ZFG A;  5DL5 A;  3EMN X;  1GFM A;  5PRN A;  3POX A;  3SYB A;  4FSP A;  2FGR A;  4RJW A;  4D65 A;  2OMF A;  1E54 A;  2Y0L A;  2J1N A;  3HW9 A;  1MPF A;  3POQ A;  2ZLD A;  3UU2 A;  2XE5 A;  4D64 A;  2PRN A;  1PHO A;  1H6S 1;  4D5U A;  3FYX A;  4AUI A;  1HXX A;  3VZU X;  5DL7 A;  3VY9 X;  4BUM X;  3VZT X;  5JDP A;  4FRT A;  4KRA A;  4LSI A;  6PRN A;  1BH3 A;  3SY7 A;  1GFO A;  2K4T A;  3PRN A;  1OPF A;  4C69 X;  2O4V A;  4FMS A;  5DL6 A;  3NSG A;  2Y0H A;  3POU A;  3WI4 A;  2FGQ X;  5DL8 A;  2Y0K A;  4LSH A;  5FVN A;  2J4U P;  1OSM A; 
#chains in the Genus database with same CATH topology
 2W80 C;  4AKR B;  2XE2 A;  4JCH A;  4FZN A;  1ZHY A;  3SZV A;  3SYS A;  4GCQ A;  4PR7 A;  3PGU A;  2QTK A;  1IZN A;  4UB8 O;  3PQU A;  3SY9 A;  2F1C X;  3AA0 B;  3HWB A;  3QRA A;  1QJ9 A;  3T0S A;  4O4X A;  4IL6 O;  2KZ7 B;  3AA7 A;  4AKM A;  2XG6 A;  3DWO X;  2M06 A;  3DA4 A;  3O0E A;  3T20 A;  5D5D A;  1GFP A;  4GCP A;  3POR A;  4AZL A;  2WJR A;  3AA1 B;  5ADX L;  1QJP A;  1BT9 A;  1GFQ A;  2AXT O;  2XTR A;  3K19 A;  4RLB A;  3C5O A;  3JTY A;  4B61 A;  1GFN A;  4FRX A;  5EE2 A;  3RBH A;  3WI5 A;  3BRZ A;  1ZHX A;  2F1V A;  1HXT A;  2R4L A;  3A2S X;  4GCS A;  3AAA B;  4LSF A;  2XE3 A;  4RJX A;  1YS5 A;  1PRN A;  4FT6 A;  3GP6 A;  4LSE A;  5KAI O;  3UAQ A;  3VZW X;  4FOZ A;  4JFB A;  3VY8 X;  4AKR A;  2XE1 A;  2Y2X A;  4N58 A;  3WU2 O;  2R4N A;  5AFU K;  2ERV A;  4FQE A;  1HXU A;  2X27 X;  3AA0 A;  4G76 A;  7PRN A;  2MNH A;  2IWV A;  2ODJ A;  4FSO A;  4KR8 A;  2K0L A;  2KZ7 A;  2F1T A;  3AA6 B;  4AYN A;  2LHF A;  8PRN A;  3SZD A;  4AYE C;  2POR A;  3JCU O;  3LK3 B;  1S5L O;  4KR4 A;  4FES A;  3T24 A;  1BXW A;  3UPG A;  3TZG A;  2ZFG A;  5DL5 A;  3EMN X;  3A0H O;  1GFM A;  3AA1 A;  4XNL A;  2MHL A;  3KVD D;  4AYM C;  4FZL A;  2JQY A;  3PQS A;  3POX A;  5PRN A;  3SYB A;  2XTQ A;  3LK4 1;  5T5F A;  3DA3 A;  2YNK A;  4FSP A;  2FGR A;  1T1L A;  3LK2 B;  2R4O A;  5ADX K;  2KDY A;  2W81 C;  3AAA A;  4RJW A;  2OMF A;  5GTI O;  4D65 A;  1E54 A;  3VE2 A;  2Y0L A;  5G26 A;  2J1N A;  1Q9G A;  1QJ8 A;  3HW9 A;  2KXP B;  1MPF A;  3HOL A;  3POQ A;  3DWN A;  2KC0 A;  4G75 A;  4N74 A;  2N2L A;  2R89 A;  4AFK A;  4E1T A;  5B66 O;  4O49 A;  2ZLD A;  1T16 A;  5TIS O;  3UU2 A;  2XE5 A;  1ZHW A;  3AA6 A;  5G39 A;  4D64 A;  1P4T A;  2GE4 A;  3AAE B;  2PRN A;  2R8A A;  3LK3 A;  4O3W A;  1PHO A;  1H6S 1;  4D5U A;  4F4B A;  2WJQ A;  2XMX A;  3FYX A;  4XNK A;  5G38 A;  4AUI A;  2X9K A;  5KAF O;  1HXX A;  2IWW A;  1THQ A;  3VZU X;  5DL7 A;  4C4V B;  3VY9 X;  4GHB A;  4K3C A;  1ORM A;  4QQ1 A;  4BUM X;  5AFU L;  3VZT X;  5JDP A;  4O3Y A;  3LK2 A;  1ZHT A;  3DZM A;  2YPV A;  4FRT A;  4KRA A;  4LSI A;  2JMM A;  4N75 A;  3A0B O;  4UB6 O;  4AYD C;  3KZI O;  6PRN A;  2N2M A;  4FUV A;  1BH3 A;  2LFU A;  3G7G A;  5GTH O;  4N59 A;  4RLC A;  1Q9F A;  3SY7 A;  1GFO A;  1IZN B;  2K4T A;  3PRN A;  2KXP A;  4PUX A;  3V8U A;  4U9C A;  4C00 A;  4K3B A;  3PGS A;  1OPF A;  3AA7 B;  4Z3T A;  2R88 A;  5G3A A;  3HOE A;  4O3X B;  2R4P A;  2Y7S A;  5E79 O;  4C69 X;  4PJ0 O;  1ZHZ A;  3AAE A;  2O4V A;  3QRC A;  4FMS A;  4FZM A;  5DL6 A;  3NJT A;  4E1S A;  3BS0 A;  4AYI D;  3LK4 2;  3NSG A;  4O3Z A;  2Y0H A;  3POU A;  5B5E O;  1G90 A;  3PGR A;  3WI4 A;  2FGQ X;  2M07 A;  5DL8 A;  3VE1 A;  5IYU A;  4RL9 A;  1MM5 A;  3PF1 A;  5H2F O;  2Y0K A;  1MM4 A;  4LSH A;  2WVP A;  5FVN A;  4C4V A;  2J4U P;  4GF4 A;  4CTD A;  3BRY A;  5GV0 A;  4O4U A;  1OSM A; 
#chains in the Genus database with same CATH homology
 2W80 C;  4AKR B;  2XE2 A;  4JCH A;  4FZN A;  1ZHY A;  3SZV A;  3SYS A;  4GCQ A;  2QTK A;  1IZN A;  3SY9 A;  3PQU A;  3AA0 B;  3HWB A;  3QRA A;  1QJ9 A;  3T0S A;  4O4X A;  4AKM A;  2KZ7 B;  3AA7 A;  2XG6 A;  2M06 A;  3DA4 A;  3O0E A;  3T20 A;  5D5D A;  1GFP A;  4GCP A;  3POR A;  4AZL A;  3AA1 B;  5ADX L;  1QJP A;  1BT9 A;  1GFQ A;  2XTR A;  3K19 A;  4RLB A;  3C5O A;  3JTY A;  4B61 A;  1GFN A;  4FRX A;  5EE2 A;  3RBH A;  3WI5 A;  1ZHX A;  2F1V A;  1HXT A;  3A2S X;  4GCS A;  3AAA B;  4LSF A;  2XE3 A;  4RJX A;  1YS5 A;  1PRN A;  4FT6 A;  3GP6 A;  4LSE A;  3UAQ A;  3VZW X;  4FOZ A;  4JFB A;  3VY8 X;  4AKR A;  2XE1 A;  2Y2X A;  4N58 A;  5AFU K;  2ERV A;  1HXU A;  2X27 X;  3AA0 A;  4G76 A;  7PRN A;  2MNH A;  4FSO A;  2ODJ A;  4KR8 A;  2K0L A;  2KZ7 A;  2F1T A;  3AA6 B;  4AYN A;  2LHF A;  8PRN A;  3SZD A;  4AYE C;  2POR A;  3LK3 B;  4KR4 A;  4FES A;  3T24 A;  1BXW A;  3UPG A;  3TZG A;  2ZFG A;  5DL5 A;  3EMN X;  1GFM A;  3AA1 A;  4XNL A;  2MHL A;  3KVD D;  4AYM C;  4FZL A;  3PQS A;  5PRN A;  3POX A;  3SYB A;  2XTQ A;  3LK4 1;  5T5F A;  3DA3 A;  2YNK A;  4FSP A;  2FGR A;  3LK2 B;  5ADX K;  2W81 C;  2KDY A;  3AAA A;  4RJW A;  2OMF A;  4D65 A;  1E54 A;  3VE2 A;  2Y0L A;  5G26 A;  2J1N A;  1Q9G A;  1QJ8 A;  3HW9 A;  2KXP B;  1MPF A;  3HOL A;  3POQ A;  2KC0 A;  4G75 A;  2N2L A;  4AFK A;  4E1T A;  4O49 A;  2ZLD A;  3UU2 A;  2XE5 A;  1ZHW A;  3AA6 A;  4D64 A;  1P4T A;  2GE4 A;  3AAE B;  2PRN A;  3LK3 A;  4O3W A;  1PHO A;  1H6S 1;  4D5U A;  4F4B A;  2XMX A;  3FYX A;  4XNK A;  4AUI A;  1HXX A;  1THQ A;  3VZU X;  5DL7 A;  3VY9 X;  4GHB A;  1ORM A;  4QQ1 A;  4BUM X;  5AFU L;  3VZT X;  5JDP A;  4O3Y A;  3LK2 A;  1ZHT A;  2YPV A;  4FRT A;  4KRA A;  4LSI A;  2JMM A;  4AYD C;  6PRN A;  2N2M A;  4FUV A;  1BH3 A;  2LFU A;  3G7G A;  4N59 A;  4RLC A;  1Q9F A;  3SY7 A;  1GFO A;  1IZN B;  2K4T A;  3PRN A;  2KXP A;  4PUX A;  3V8U A;  4U9C A;  1OPF A;  3AA7 B;  4Z3T A;  3HOE A;  4O3X B;  2Y7S A;  4C69 X;  1ZHZ A;  3AAE A;  2O4V A;  3QRC A;  4FMS A;  4FZM A;  5DL6 A;  4E1S A;  4AYI D;  3LK4 2;  3NSG A;  4O3Z A;  2Y0H A;  3POU A;  1G90 A;  3WI4 A;  2FGQ X;  2M07 A;  5DL8 A;  3VE1 A;  5IYU A;  4RL9 A;  1MM5 A;  2Y0K A;  1MM4 A;  4LSH A;  5FVN A;  2J4U P;  4GF4 A;  5GV0 A;  4O4U A;  1OSM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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