3EMNX

The crystal structure of mouse vdac1 at 2.3 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
283
structure length
283
Chain Sequence
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating
pubmed doi rcsb
molecule tags Membrane protein
source organism Mus musculus
molecule keywords Voltage-dependent anion-selective channel protein 1
total genus 63
structure length 283
sequence length 283
ec nomenclature
pdb deposition date 2008-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 3emnX00
2XE2A 4GCPA 2PRNA 4RJWA 3EMNX 3T20A 1GFMA 6PRNA 4GCQA 2O4VA 1GFQA 4LSFA 4D65A 4BUMX 2Y0HA 2Y2XA 3FYXA 1PRNA 4FRTA 2ODJA 1HXXA 1OSMA 5PRNA 4LSEA 2ZFGA 2OMFA 3VY9X 1GFOA 4D64A 3O0EA 2J4UP 3T24A 4FSPA 3VZTX 4GCSA 2K4TA 3SZVA 3UU2A 1GFNA 2QTKA 1E54A 2ZLDA 3UPGA 4KRAA 2XE5A 3WI5A 4JFBA 1HXUA 1BT9A 4KR8A 2XG6A 3NSGA 3POXA 3PORA 2PORA 1OPFA 2FGQX 3VZUX 3A2SX 2J1NA 1GFPA 2XE3A 3SY7A 3POUA 4FT6A 2FGRA 4AUIA 4FRXA 3K19A 3SY9A 5DL8A 3SYSA 3WI4A 4D5UA 4FMSA 3PRNA 4FOZA 3SZDA 1PHOA 7PRNA 4LSIA 3JTYA 4KR4A 4LSHA 5FVNA 2Y0KA 8PRNA 3POQA 4RJXA 3SYBA 3HW9A 5JDPA 1BH3A 5DL5A 4FSOA 2XE1A 3HWBA 2Y0LA 4C69X 5DL7A 1H6S1 3T0SA 3VZWX 3VY8X 5DL6A 1HXTA 1MPFA
chains in the Genus database with same CATH superfamily
4O3ZA 3DWOX 2XE2A 3JCUO 4GCPA 2PRNA 4RJWA 5KAFO 1Q9GA 5TISO 3EMNX 3T20A 1GFMA 2KC0A 6PRNA 2AXTO 4GCQA 1ZHYA 2O4VA 3AA6B 1GFQA 3QRAA 4LSFA 4AYDC 4D65A 2WVPA 4BUMX 2Y0HA 2XMXA 3AA0B 2IWVA 2Y2XA 1QJ9A 1ZHTA 4O49A 4AYMC 3PGRA 2JMMA 2ERVA 5B5EO 3FYXA 4N58A 1PRNA 5D5DA 2M07A 4QQ1A 3PGUA 4O3YA 3UAQA 5G38A 5GV0A 3KZIO 3TZGA 3V8UA 4FRTA 4O4XA 2ODJA 4AKRA 1HXXA 1OSMA 4E1SA 1QJ8A 3AA7B 3AAEA 4FZLA 4LSEA 4O3XB 2ZFGA 2OMFA 3A0BO 5PRNA 3VY9X 4CTDA 1GFOA 5E79O 4D64A 3O0EA 5G3AA 2J4UP 1Q9FA 1IZNA 5T5FA 3T24A 5ADXL 4FSPA 2N2MA 2X9KA 3VZTX 1ZHWA 3BRZA 3LK3B 4B61A 2R8AA 3DWNA 2K4TA 3AAAB 4GCSA 2WJQA 5EE2A 3AA6A 3SZVA 2KZ7B 3UU2A 4N75A 4C00A 1GFNA 2R4LA 2R88A 5AFUK 2LFUA 4G76A 4RLBA 5IYUA 3PF1A 4XNKA 3HOLA 2R4PA 2QTKA 3AA0A 4RLCA 4FUVA 1E54A 2ZLDA 5AFUL 1T1LA 3UPGA 4KRAA 2XE5A 1G90A 4PJ0O 3WI5A 4JFBA 3PQSA 1HXUA 1BT9A 3AA1B 4AKMA 4RL9A 4UB6O 5H2FO 4KR8A 2MNHA 2XG6A 2F1VA 3NSGA 3POXA 3PORA 4AZLA 2F1CX 2PORA 1OPFA 3AA7A 4FQEA 2FGQX 4K3CA 2YPVA 2J1NA 3A2SX 3VE1A 3VZUX 2JQYA 1GFPA 3PGSA 4AYEC 4AYID 5ADXK 2XE3A 4N74A 2X27X 4XNLA 3QRCA 1MM4A 2MHLA 3VE2A 1YS5A 5B66O 4O3WA 3SY7A 3PQUA 3POUA 4FT6A 3LK3A 5G26A 2N2LA 2FGRA 4PR7A 3LK41 3DA3A 4AUIA 3AAAA 1P4TA 4FRXA 3K19A 2KZ7A 3SY9A 5DL8A 1ZHZA 4JCHA 1ZHXA 3LK42 3LK2B 3DA4A 2W81C 2XTRA 4FESA 4FZNA 3SYSA 4G75A 3WI4A 4D5UA 2M06A 4E1TA 2GE4A 4FMSA 3PRNA 2KXPB 4FOZA 3NJTA 1PHOA 3DZMA 3KVDD 4IL6O 3AA1A 3RBHA 7PRNA 2LHFA 1S5LO 2YNKA 4C4VB 4U9CA 3C5OA 1MM5A 4LSIA 2IWWA 3JTYA 4GHBA 2R4NA 5KAIO 4KR4A 4LSHA 4K3BA 2F1TA 4N59A 3BS0A 5FVNA 2Y0KA 2W80C 2WJRA 8PRNA 3A0HO 3POQA 4RJXA 3SZDA 1ORMA 3WU2O 4PUXA 3SYBA 4AFKA 1QJPA 3GP6A 4O4UA 3G7GA 3HW9A 5JDPA 1THQA 2Y7SA 1BH3A 5DL5A 1T16A 2R4OA 4FSOA 2XE1A 4F4BA 3LK2A 4Z3TA 3HWBA 1BXWA 2Y0LA 4C69X 2XTQA 2K0LA 3HOEA 1H6S1 4GF4A 5DL7A 5GTIO 4AKRB 2KXPA 3T0SA 2KDYA 3AAEB 3VZWX 4AYNA 5G39A 2R89A 3VY8X 4C4VA 4FZMA 5GTHO 5DL6A 1HXTA 1IZNB 3BRYA 1MPFA 4UB8O
chains in the Genus database with same CATH topology
4O3ZA 2XE2A 4GCPA 2PRNA 4RJWA 1Q9GA 3EMNX 3T20A 1GFMA 2KC0A 6PRNA 4GCQA 1ZHYA 2O4VA 3AA6B 1GFQA 3QRAA 4LSFA 4AYDC 4D65A 4BUMX 2Y0HA 2XMXA 3AA0B 2Y2XA 1QJ9A 1ZHTA 4O49A 4AYMC 2JMMA 2ERVA 3FYXA 4N58A 1PRNA 5D5DA 2M07A 4QQ1A 4O3YA 3UAQA 5GV0A 3TZGA 3V8UA 4FRTA 4O4XA 2ODJA 4AKRA 1HXXA 1OSMA 4E1SA 1QJ8A 3AA7B 3AAEA 4FZLA 4LSEA 4O3XB 2ZFGA 2OMFA 5PRNA 3VY9X 5ADXK 1GFOA 4D64A 3O0EA 2J4UP 1Q9FA 1IZNA 5T5FA 3T24A 5ADXL 4FSPA 2N2MA 3VZTX 1ZHWA 3LK3B 4B61A 4GCSA 2K4TA 3AAAB 5EE2A 3SZVA 3UU2A 3AA6A 2KZ7B 1GFNA 5AFUK 2LFUA 4G76A 4RLBA 4XNKA 3HOLA 3AA0A 2QTKA 4RLCA 4FUVA 1E54A 2ZLDA 5AFUL 3UPGA 1G90A 4KRAA 2XE5A 3WI5A 4AKMA 4JFBA 3PQSA 1HXUA 1BT9A 3AA1B 4RL9A 4KR8A 2XG6A 2MNHA 2F1VA 3NSGA 3POXA 3PORA 4AZLA 2PORA 1OPFA 3AA7A 2FGQX 3VZUX 2YPVA 2J1NA 3A2SX 3VE1A 4AYID 4AYNA 1GFPA 4AYEC 2XE3A 2X27X 4XNLA 3QRCA 1MM4A 2MHLA 3VE2A 1YS5A 4O3WA 3SY7A 3PQUA 3POUA 4FT6A 3LK3A 5G26A 2N2LA 2FGRA 4AUIA 3LK41 3DA3A 3AAAA 1P4TA 4FRXA 3K19A 2KZ7A 3SY9A 5DL8A 1ZHZA 4JCHA 1ZHXA 3LK42 3LK2B 3DA4A 2W81C 2XTRA 4FESA 4FZNA 3SYSA 4G75A 3WI4A 4D5UA 2M06A 4E1TA 2GE4A 4FMSA 3PRNA 2KXPB 4FOZA 3SZDA 1PHOA 3RBHA 3KVDD 3AA1A 7PRNA 2LHFA 2YNKA 4U9CA 3C5OA 1MM5A 4LSIA 3JTYA 4GHBA 4KR4A 4LSHA 2F1TA 4N59A 5FVNA 2Y0KA 2W80C 8PRNA 3POQA 4RJXA 1ORMA 4AFKA 4PUXA 3SYBA 1QJPA 3GP6A 4O4UA 3G7GA 3HW9A 5JDPA 1THQA 2Y7SA 1BH3A 5DL5A 4FSOA 2XE1A 4F4BA 3LK2A 4Z3TA 3HWBA 1BXWA 2Y0LA 4C69X 2XTQA 2K0LA 3HOEA 1H6S1 4GF4A 5DL7A 4AKRB 2KXPA 3T0SA 2KDYA 3AAEB 3VZWX 3VY8X 4FZMA 5DL6A 1HXTA 1IZNB 1MPFA 5IYUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XE2 A;  4GCP A;  2PRN A;  4RJW A;  3EMN X;  3T20 A;  1GFM A;  6PRN A;  4GCQ A;  2O4V A;  1GFQ A;  4LSF A;  4D65 A;  4BUM X;  2Y0H A;  2Y2X A;  3FYX A;  1PRN A;  4FRT A;  2ODJ A;  1HXX A;  1OSM A;  5PRN A;  4LSE A;  2ZFG A;  2OMF A;  3VY9 X;  1GFO A;  4D64 A;  3O0E A;  2J4U P;  3T24 A;  4FSP A;  3VZT X;  4GCS A;  2K4T A;  3SZV A;  3UU2 A;  1GFN A;  2QTK A;  1E54 A;  2ZLD A;  3UPG A;  4KRA A;  2XE5 A;  3WI5 A;  4JFB A;  1HXU A;  1BT9 A;  4KR8 A;  2XG6 A;  3NSG A;  3POX A;  3POR A;  2POR A;  1OPF A;  2FGQ X;  3VZU X;  3A2S X;  2J1N A;  1GFP A;  2XE3 A;  3SY7 A;  3POU A;  4FT6 A;  2FGR A;  4AUI A;  4FRX A;  3K19 A;  3SY9 A;  5DL8 A;  3SYS A;  3WI4 A;  4D5U A;  4FMS A;  3PRN A;  4FOZ A;  3SZD A;  1PHO A;  7PRN A;  4LSI A;  3JTY A;  4KR4 A;  4LSH A;  5FVN A;  2Y0K A;  8PRN A;  3POQ A;  4RJX A;  3SYB A;  3HW9 A;  5JDP A;  1BH3 A;  5DL5 A;  4FSO A;  2XE1 A;  3HWB A;  2Y0L A;  4C69 X;  5DL7 A;  1H6S 1;  3T0S A;  3VZW X;  3VY8 X;  5DL6 A;  1HXT A;  1MPF A; 
#chains in the Genus database with same CATH topology
 4O3Z A;  3DWO X;  2XE2 A;  3JCU O;  4GCP A;  2PRN A;  4RJW A;  5KAF O;  1Q9G A;  5TIS O;  3EMN X;  3T20 A;  1GFM A;  2KC0 A;  6PRN A;  2AXT O;  4GCQ A;  1ZHY A;  2O4V A;  3AA6 B;  1GFQ A;  3QRA A;  4LSF A;  4AYD C;  4D65 A;  2WVP A;  4BUM X;  2Y0H A;  2XMX A;  3AA0 B;  2IWV A;  2Y2X A;  1QJ9 A;  1ZHT A;  4O49 A;  4AYM C;  3PGR A;  2JMM A;  2ERV A;  5B5E O;  3FYX A;  4N58 A;  1PRN A;  5D5D A;  2M07 A;  4QQ1 A;  3PGU A;  4O3Y A;  3UAQ A;  5G38 A;  5GV0 A;  3KZI O;  3TZG A;  3V8U A;  4FRT A;  4O4X A;  2ODJ A;  4AKR A;  1HXX A;  1OSM A;  4E1S A;  1QJ8 A;  3AA7 B;  3AAE A;  4FZL A;  4LSE A;  4O3X B;  2ZFG A;  2OMF A;  3A0B O;  5PRN A;  3VY9 X;  4CTD A;  1GFO A;  5E79 O;  4D64 A;  3O0E A;  5G3A A;  2J4U P;  1Q9F A;  1IZN A;  5T5F A;  3T24 A;  5ADX L;  4FSP A;  2N2M A;  2X9K A;  3VZT X;  1ZHW A;  3BRZ A;  3LK3 B;  4B61 A;  2R8A A;  3DWN A;  2K4T A;  3AAA B;  4GCS A;  2WJQ A;  5EE2 A;  3AA6 A;  3SZV A;  2KZ7 B;  3UU2 A;  4N75 A;  4C00 A;  1GFN A;  2R4L A;  2R88 A;  5AFU K;  2LFU A;  4G76 A;  4RLB A;  5IYU A;  3PF1 A;  4XNK A;  3HOL A;  2R4P A;  2QTK A;  3AA0 A;  4RLC A;  4FUV A;  1E54 A;  2ZLD A;  5AFU L;  1T1L A;  3UPG A;  4KRA A;  2XE5 A;  1G90 A;  4PJ0 O;  3WI5 A;  4JFB A;  3PQS A;  1HXU A;  1BT9 A;  3AA1 B;  4AKM A;  4RL9 A;  4UB6 O;  5H2F O;  4KR8 A;  2MNH A;  2XG6 A;  2F1V A;  3NSG A;  3POX A;  3POR A;  4AZL A;  2F1C X;  2POR A;  1OPF A;  3AA7 A;  4FQE A;  2FGQ X;  4K3C A;  2YPV A;  2J1N A;  3A2S X;  3VE1 A;  3VZU X;  2JQY A;  1GFP A;  3PGS A;  4AYE C;  4AYI D;  5ADX K;  2XE3 A;  4N74 A;  2X27 X;  4XNL A;  3QRC A;  1MM4 A;  2MHL A;  3VE2 A;  1YS5 A;  5B66 O;  4O3W A;  3SY7 A;  3PQU A;  3POU A;  4FT6 A;  3LK3 A;  5G26 A;  2N2L A;  2FGR A;  4PR7 A;  3LK4 1;  3DA3 A;  4AUI A;  3AAA A;  1P4T A;  4FRX A;  3K19 A;  2KZ7 A;  3SY9 A;  5DL8 A;  1ZHZ A;  4JCH A;  1ZHX A;  3LK4 2;  3LK2 B;  3DA4 A;  2W81 C;  2XTR A;  4FES A;  4FZN A;  3SYS A;  4G75 A;  3WI4 A;  4D5U A;  2M06 A;  4E1T A;  2GE4 A;  4FMS A;  3PRN A;  2KXP B;  4FOZ A;  3NJT A;  1PHO A;  3DZM A;  3KVD D;  4IL6 O;  3AA1 A;  3RBH A;  7PRN A;  2LHF A;  1S5L O;  2YNK A;  4C4V B;  4U9C A;  3C5O A;  1MM5 A;  4LSI A;  2IWW A;  3JTY A;  4GHB A;  2R4N A;  5KAI O;  4KR4 A;  4LSH A;  4K3B A;  2F1T A;  4N59 A;  3BS0 A;  5FVN A;  2Y0K A;  2W80 C;  2WJR A;  8PRN A;  3A0H O;  3POQ A;  4RJX A;  3SZD A;  1ORM A;  3WU2 O;  4PUX A;  3SYB A;  4AFK A;  1QJP A;  3GP6 A;  4O4U A;  3G7G A;  3HW9 A;  5JDP A;  1THQ A;  2Y7S A;  1BH3 A;  5DL5 A;  1T16 A;  2R4O A;  4FSO A;  2XE1 A;  4F4B A;  3LK2 A;  4Z3T A;  3HWB A;  1BXW A;  2Y0L A;  4C69 X;  2XTQ A;  2K0L A;  3HOE A;  1H6S 1;  4GF4 A;  5DL7 A;  5GTI O;  4AKR B;  2KXP A;  3T0S A;  2KDY A;  3AAE B;  3VZW X;  4AYN A;  5G39 A;  2R89 A;  3VY8 X;  4C4V A;  4FZM A;  5GTH O;  5DL6 A;  1HXT A;  1IZN B;  3BRY A;  1MPF A;  4UB8 O; 
#chains in the Genus database with same CATH homology
 4O3Z A;  2XE2 A;  4GCP A;  2PRN A;  4RJW A;  1Q9G A;  3EMN X;  3T20 A;  1GFM A;  2KC0 A;  6PRN A;  4GCQ A;  1ZHY A;  2O4V A;  3AA6 B;  1GFQ A;  3QRA A;  4LSF A;  4AYD C;  4D65 A;  4BUM X;  2Y0H A;  2XMX A;  3AA0 B;  2Y2X A;  1QJ9 A;  1ZHT A;  4O49 A;  4AYM C;  2JMM A;  2ERV A;  3FYX A;  4N58 A;  1PRN A;  5D5D A;  2M07 A;  4QQ1 A;  4O3Y A;  3UAQ A;  5GV0 A;  3TZG A;  3V8U A;  4FRT A;  4O4X A;  2ODJ A;  4AKR A;  1HXX A;  1OSM A;  4E1S A;  1QJ8 A;  3AA7 B;  3AAE A;  4FZL A;  4LSE A;  4O3X B;  2ZFG A;  2OMF A;  5PRN A;  3VY9 X;  5ADX K;  1GFO A;  4D64 A;  3O0E A;  2J4U P;  1Q9F A;  1IZN A;  5T5F A;  3T24 A;  5ADX L;  4FSP A;  2N2M A;  3VZT X;  1ZHW A;  3LK3 B;  4B61 A;  4GCS A;  2K4T A;  3AAA B;  5EE2 A;  3SZV A;  3UU2 A;  3AA6 A;  2KZ7 B;  1GFN A;  5AFU K;  2LFU A;  4G76 A;  4RLB A;  4XNK A;  3HOL A;  3AA0 A;  2QTK A;  4RLC A;  4FUV A;  1E54 A;  2ZLD A;  5AFU L;  3UPG A;  1G90 A;  4KRA A;  2XE5 A;  3WI5 A;  4AKM A;  4JFB A;  3PQS A;  1HXU A;  1BT9 A;  3AA1 B;  4RL9 A;  4KR8 A;  2XG6 A;  2MNH A;  2F1V A;  3NSG A;  3POX A;  3POR A;  4AZL A;  2POR A;  1OPF A;  3AA7 A;  2FGQ X;  3VZU X;  2YPV A;  2J1N A;  3A2S X;  3VE1 A;  4AYI D;  4AYN A;  1GFP A;  4AYE C;  2XE3 A;  2X27 X;  4XNL A;  3QRC A;  1MM4 A;  2MHL A;  3VE2 A;  1YS5 A;  4O3W A;  3SY7 A;  3PQU A;  3POU A;  4FT6 A;  3LK3 A;  5G26 A;  2N2L A;  2FGR A;  4AUI A;  3LK4 1;  3DA3 A;  3AAA A;  1P4T A;  4FRX A;  3K19 A;  2KZ7 A;  3SY9 A;  5DL8 A;  1ZHZ A;  4JCH A;  1ZHX A;  3LK4 2;  3LK2 B;  3DA4 A;  2W81 C;  2XTR A;  4FES A;  4FZN A;  3SYS A;  4G75 A;  3WI4 A;  4D5U A;  2M06 A;  4E1T A;  2GE4 A;  4FMS A;  3PRN A;  2KXP B;  4FOZ A;  3SZD A;  1PHO A;  3RBH A;  3KVD D;  3AA1 A;  7PRN A;  2LHF A;  2YNK A;  4U9C A;  3C5O A;  1MM5 A;  4LSI A;  3JTY A;  4GHB A;  4KR4 A;  4LSH A;  2F1T A;  4N59 A;  5FVN A;  2Y0K A;  2W80 C;  8PRN A;  3POQ A;  4RJX A;  1ORM A;  4AFK A;  4PUX A;  3SYB A;  1QJP A;  3GP6 A;  4O4U A;  3G7G A;  3HW9 A;  5JDP A;  1THQ A;  2Y7S A;  1BH3 A;  5DL5 A;  4FSO A;  2XE1 A;  4F4B A;  3LK2 A;  4Z3T A;  3HWB A;  1BXW A;  2Y0L A;  4C69 X;  2XTQ A;  2K0L A;  3HOE A;  1H6S 1;  4GF4 A;  5DL7 A;  4AKR B;  2KXP A;  3T0S A;  2KDY A;  3AAE B;  3VZW X;  3VY8 X;  4FZM A;  5DL6 A;  1HXT A;  1IZN B;  1MPF A;  5IYU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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