4AKMA

Crystal structure of the human lysosome-associated membrane protein lamp-3 (aka dc-lamp)
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
155
structure length
155
Chain Sequence
VKTGIYQVLNGSRLCIKAEMGIQLIVQDKESVFSPRRYFNIDPNATQASGNCGTRKSNLLLNFQGGFVNLTFTKDEESYYISEVGAYLTVSDPETVYQGIKHAVVMFQTAVGHSFKCVSEQSLQLSAHLQVKTTDVQLQAFDFEDDHFGNVDECS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structure of the Conserved Domain of the Dc Lysosomal Associated Membrane Protein: Implications for the Lysosomal Glycocalyx.
pubmed doi rcsb
molecule tags Membrane protein
source organism Homo sapiens
molecule keywords LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 3
total genus 22
structure length 155
sequence length 155
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01299 Lamp Lysosome-associated membrane glycoprotein (Lamp)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.110 Mainly Beta Beta Barrel Porin Porin 4akmA00
4AKMA 5GV0A
chains in the Genus database with same CATH superfamily
3SY7A 4XNLA 3V8UA 4AYMC 2ODJA 3T20A 2J1NA 5PRNA 4AYDC 1BXWA 4RLCA 4JFBA 1QJ9A 3PF1A 6PRNA 4KRAA 5DL7A 1HXTA 2OMFA 4AYNA 1E54A 2M07A 4RL9A 1H6S1 4AFKA 2XG6A 2XE3A 3JCUO 4N75A 2R4LA 3WI4A 1ZHXA 4N58A 4AYID 4C69X 5AFUK 5JDPA 3POQA 1Q9GA 3C5OA 3UAQA 2Y0HA 4AKMA 3TZGA 1GFOA 3G7GA 2R4OA 2F1TA 1THQA 4C00A 4AYEC 1S5LO 3AA6A 3DA3A 3T24A 1P4TA 3BRZA 3UU2A 3DZMA 1MPFA 2Y2XA 4O3XB 5G39A 3A0HO 3VZTX 3UPGA 3DWOX 4G75A 4FSPA 3AA6B 2QTKA 1HXUA 2K4TA 3RBHA 4PJ0O 3AA1B 1QJ8A 1ZHWA 5KAFO 3SYBA 4BUMX 1PRNA 2F1VA 4G76A 4PR7A 3HOLA 3VY9X 2JQYA 1GFMA 1GFPA 1Q9FA 3AA0B 4FRTA 2MNHA 1HXXA 3JTYA 3PQUA 2K0LA 4UB6O 5G3AA 1QJPA 2KDYA 2XE1A 1GFNA 5GTHO 4FZNA 3HW9A 1ORMA 2AXTO 1BT9A 2ERVA 4O49A 4O4UA 5KAIO 7PRNA 2XTQA 2R89A 1GFQA 3HOEA 2N2LA 2LHFA 3PGSA 3SYSA 4GCPA 3NJTA 3DWNA 3PGUA 3A0BO 4FMSA 4LSEA 4O4XA 5GTIO 3SZDA 1MM5A 4Z3TA 1OSMA 4GCQA 5GV0A 1T1LA 3AA1A 4FRXA 5G26A 3VZWX 4RJXA 4AUIA 4E1SA 4FSOA 4KR4A 5B66O 2WVPA 5E79O 3PORA 4K3CA 3POXA 3AAEB 2KZ7A 3AAAB 4FZLA 4CTDA 3AA0A 3SZVA 2GE4A 4FT6A 4O3YA 8PRNA 3A2SX 2R8AA 5EE2A 2KZ7B 2ZFGA 1IZNA 3LK3A 3FYXA 3NSGA 5H2FO 2M06A 4UB8O 3LK41 2W80C 5D5DA 2Y0LA 5DL8A 3WI5A 2WJRA 4D65A 1IZNB 3LK3B 2YPVA 4LSFA 4E1TA 4O3ZA 3KZIO 3BS0A 5DL5A 5ADXK 4GHBA 3KVDD 3PGRA 4O3WA 2PORA 3POUA 2JMMA 2X27X 5B5EO 3HWBA 2MHLA 4QQ1A 2PRNA 1G90A 1YS5A 2WJQA 3AA7A 4LSHA 5ADXL 3VY8X 4D64A 3WU2O 3AAEA 2J4UP 3AAAA 4FUVA 2R4PA 1BH3A 2W81C 2XTRA 3QRCA 1ZHYA 4U9CA 4C4VB 4IL6O 4N59A 4D5UA 3AA7B 4FZMA 1ZHZA 2KXPB 4F4BA 4N74A 3EMNX 4LSIA 5IYUA 1OPFA 4FQEA 3GP6A 2R88A 3QRAA 4PUXA 2XE2A 2ZLDA 4FESA 5G38A 2Y7SA 2IWWA 2YNKA 3VE2A 5T5FA 1ZHTA 4FOZA 3VE1A 4K3BA 2O4VA 5DL6A 4XNKA 2F1CX 2Y0KA 3LK42 3O0EA 4AZLA 2XE5A 3T0SA 4B61A 4RJWA 2IWVA 4GCSA 2X9KA 4AKRA 5TISO 3LK2A 3PRNA 3VZUX 1T16A 2LFUA 2FGQX 2N2MA 2KC0A 4GF4A 4JCHA 4RLBA 3PQSA 5FVNA 4KR8A 4C4VA 5AFUL 4AKRB 3SY9A 3LK2B 3DA4A 2R4NA 3K19A 1PHOA 2KXPA 2FGRA 1MM4A 3BRYA 2XMXA
chains in the Genus database with same CATH topology
3SY7A 4XNLA 3V8UA 4AYMC 2ODJA 3T20A 2J1NA 5PRNA 4AYDC 1BXWA 4RLCA 4JFBA 1QJ9A 6PRNA 4KRAA 5DL7A 1HXTA 2OMFA 4AYNA 1E54A 2M07A 4RL9A 1H6S1 4AFKA 2XG6A 2XE3A 3WI4A 1ZHXA 4N58A 4AYID 4C69X 5AFUK 5JDPA 3POQA 1Q9GA 3C5OA 3UAQA 2Y0HA 4AKMA 3TZGA 1GFOA 3G7GA 2F1TA 1THQA 4AYEC 3AA6A 3DA3A 3T24A 1P4TA 3UU2A 3VZTX 4O3XB 1MPFA 2Y2XA 3UPGA 4G75A 4FSPA 3AA6B 2QTKA 1HXUA 2K4TA 3RBHA 3SYBA 3AA1B 1QJ8A 1ZHWA 4BUMX 1PRNA 2F1VA 4G76A 3VY9X 3HOLA 1GFMA 1GFPA 1Q9FA 3AA0B 4FRTA 2MNHA 1HXXA 3JTYA 3PQUA 2K0LA 1QJPA 2KDYA 2XE1A 1GFNA 4FZNA 3HW9A 1ORMA 4O4UA 1BT9A 2ERVA 4O49A 7PRNA 2XTQA 1GFQA 3HOEA 2N2LA 2LHFA 3SYSA 4GCPA 3SZDA 4LSEA 4FMSA 4O4XA 4Z3TA 1MM5A 1OSMA 4GCQA 5GV0A 5G26A 3AA1A 4FRXA 3VZWX 4AUIA 4RJXA 4E1SA 4FSOA 4KR4A 3PORA 3POXA 3AAEB 2KZ7A 3AAAB 4FZLA 3AA0A 3SZVA 2GE4A 4FT6A 4O3YA 8PRNA 3A2SX 5EE2A 2KZ7B 2ZFGA 1IZNA 3LK3A 3FYXA 3NSGA 2M06A 3LK41 2W80C 5D5DA 2Y0LA 5DL8A 3WI5A 4E1TA 4D65A 1IZNB 3LK3B 2YPVA 4LSFA 5ADXK 4O3ZA 5DL5A 4GHBA 3KVDD 4O3WA 2PORA 3POUA 2JMMA 2X27X 3HWBA 2MHLA 4QQ1A 2PRNA 1G90A 1YS5A 3AA7A 4LSHA 5ADXL 3VY8X 4D64A 2J4UP 3AAEA 3AAAA 4FUVA 4U9CA 1BH3A 2W81C 2XTRA 3QRCA 1ZHYA 4D5UA 4N59A 3AA7B 4FZMA 1ZHZA 2KXPB 4F4BA 3EMNX 4LSIA 5IYUA 1OPFA 3GP6A 3QRAA 4PUXA 2XE2A 2ZLDA 4FESA 2Y7SA 2YNKA 3VE2A 5T5FA 1ZHTA 4FOZA 3VE1A 2O4VA 5DL6A 4XNKA 4AZLA 2Y0KA 3LK42 3O0EA 2XE5A 3T0SA 4B61A 4RJWA 4GCSA 4AKRA 3LK2A 3PRNA 3VZUX 2LFUA 4RLBA 2FGQX 2N2MA 2KC0A 4GF4A 4JCHA 5FVNA 3PQSA 4KR8A 5AFUL 4AKRB 3SY9A 3LK2B 3DA4A 3K19A 1PHOA 2KXPA 2FGRA 1MM4A 2XMXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AKM A;  5GV0 A; 
#chains in the Genus database with same CATH topology
 3SY7 A;  4XNL A;  3V8U A;  4AYM C;  2ODJ A;  3T20 A;  2J1N A;  5PRN A;  4AYD C;  1BXW A;  4RLC A;  4JFB A;  1QJ9 A;  3PF1 A;  6PRN A;  4KRA A;  5DL7 A;  1HXT A;  2OMF A;  4AYN A;  1E54 A;  2M07 A;  4RL9 A;  1H6S 1;  4AFK A;  2XG6 A;  2XE3 A;  3JCU O;  4N75 A;  2R4L A;  3WI4 A;  1ZHX A;  4N58 A;  4AYI D;  4C69 X;  5AFU K;  5JDP A;  3POQ A;  1Q9G A;  3C5O A;  3UAQ A;  2Y0H A;  4AKM A;  3TZG A;  1GFO A;  3G7G A;  2R4O A;  2F1T A;  1THQ A;  4C00 A;  4AYE C;  1S5L O;  3AA6 A;  3DA3 A;  3T24 A;  1P4T A;  3BRZ A;  3UU2 A;  3DZM A;  1MPF A;  2Y2X A;  4O3X B;  5G39 A;  3A0H O;  3VZT X;  3UPG A;  3DWO X;  4G75 A;  4FSP A;  3AA6 B;  2QTK A;  1HXU A;  2K4T A;  3RBH A;  4PJ0 O;  3AA1 B;  1QJ8 A;  1ZHW A;  5KAF O;  3SYB A;  4BUM X;  1PRN A;  2F1V A;  4G76 A;  4PR7 A;  3HOL A;  3VY9 X;  2JQY A;  1GFM A;  1GFP A;  1Q9F A;  3AA0 B;  4FRT A;  2MNH A;  1HXX A;  3JTY A;  3PQU A;  2K0L A;  4UB6 O;  5G3A A;  1QJP A;  2KDY A;  2XE1 A;  1GFN A;  5GTH O;  4FZN A;  3HW9 A;  1ORM A;  2AXT O;  1BT9 A;  2ERV A;  4O49 A;  4O4U A;  5KAI O;  7PRN A;  2XTQ A;  2R89 A;  1GFQ A;  3HOE A;  2N2L A;  2LHF A;  3PGS A;  3SYS A;  4GCP A;  3NJT A;  3DWN A;  3PGU A;  3A0B O;  4FMS A;  4LSE A;  4O4X A;  5GTI O;  3SZD A;  1MM5 A;  4Z3T A;  1OSM A;  4GCQ A;  5GV0 A;  1T1L A;  3AA1 A;  4FRX A;  5G26 A;  3VZW X;  4RJX A;  4AUI A;  4E1S A;  4FSO A;  4KR4 A;  5B66 O;  2WVP A;  5E79 O;  3POR A;  4K3C A;  3POX A;  3AAE B;  2KZ7 A;  3AAA B;  4FZL A;  4CTD A;  3AA0 A;  3SZV A;  2GE4 A;  4FT6 A;  4O3Y A;  8PRN A;  3A2S X;  2R8A A;  5EE2 A;  2KZ7 B;  2ZFG A;  1IZN A;  3LK3 A;  3FYX A;  3NSG A;  5H2F O;  2M06 A;  4UB8 O;  3LK4 1;  2W80 C;  5D5D A;  2Y0L A;  5DL8 A;  3WI5 A;  2WJR A;  4D65 A;  1IZN B;  3LK3 B;  2YPV A;  4LSF A;  4E1T A;  4O3Z A;  3KZI O;  3BS0 A;  5DL5 A;  5ADX K;  4GHB A;  3KVD D;  3PGR A;  4O3W A;  2POR A;  3POU A;  2JMM A;  2X27 X;  5B5E O;  3HWB A;  2MHL A;  4QQ1 A;  2PRN A;  1G90 A;  1YS5 A;  2WJQ A;  3AA7 A;  4LSH A;  5ADX L;  3VY8 X;  4D64 A;  3WU2 O;  3AAE A;  2J4U P;  3AAA A;  4FUV A;  2R4P A;  1BH3 A;  2W81 C;  2XTR A;  3QRC A;  1ZHY A;  4U9C A;  4C4V B;  4IL6 O;  4N59 A;  4D5U A;  3AA7 B;  4FZM A;  1ZHZ A;  2KXP B;  4F4B A;  4N74 A;  3EMN X;  4LSI A;  5IYU A;  1OPF A;  4FQE A;  3GP6 A;  2R88 A;  3QRA A;  4PUX A;  2XE2 A;  2ZLD A;  4FES A;  5G38 A;  2Y7S A;  2IWW A;  2YNK A;  3VE2 A;  5T5F A;  1ZHT A;  4FOZ A;  3VE1 A;  4K3B A;  2O4V A;  5DL6 A;  4XNK A;  2F1C X;  2Y0K A;  3LK4 2;  3O0E A;  4AZL A;  2XE5 A;  3T0S A;  4B61 A;  4RJW A;  2IWV A;  4GCS A;  2X9K A;  4AKR A;  5TIS O;  3LK2 A;  3PRN A;  3VZU X;  1T16 A;  2LFU A;  2FGQ X;  2N2M A;  2KC0 A;  4GF4 A;  4JCH A;  4RLB A;  3PQS A;  5FVN A;  4KR8 A;  4C4V A;  5AFU L;  4AKR B;  3SY9 A;  3LK2 B;  3DA4 A;  2R4N A;  3K19 A;  1PHO A;  2KXP A;  2FGR A;  1MM4 A;  3BRY A;  2XMX A; 
#chains in the Genus database with same CATH homology
 3SY7 A;  4XNL A;  3V8U A;  4AYM C;  2ODJ A;  3T20 A;  2J1N A;  5PRN A;  4AYD C;  1BXW A;  4RLC A;  4JFB A;  1QJ9 A;  6PRN A;  4KRA A;  5DL7 A;  1HXT A;  2OMF A;  4AYN A;  1E54 A;  2M07 A;  4RL9 A;  1H6S 1;  4AFK A;  2XG6 A;  2XE3 A;  3WI4 A;  1ZHX A;  4N58 A;  4AYI D;  4C69 X;  5AFU K;  5JDP A;  3POQ A;  1Q9G A;  3C5O A;  3UAQ A;  2Y0H A;  4AKM A;  3TZG A;  1GFO A;  3G7G A;  2F1T A;  1THQ A;  4AYE C;  3AA6 A;  3DA3 A;  3T24 A;  1P4T A;  3UU2 A;  3VZT X;  4O3X B;  1MPF A;  2Y2X A;  3UPG A;  4G75 A;  4FSP A;  3AA6 B;  2QTK A;  1HXU A;  2K4T A;  3RBH A;  3SYB A;  3AA1 B;  1QJ8 A;  1ZHW A;  4BUM X;  1PRN A;  2F1V A;  4G76 A;  3VY9 X;  3HOL A;  1GFM A;  1GFP A;  1Q9F A;  3AA0 B;  4FRT A;  2MNH A;  1HXX A;  3JTY A;  3PQU A;  2K0L A;  1QJP A;  2KDY A;  2XE1 A;  1GFN A;  4FZN A;  3HW9 A;  1ORM A;  4O4U A;  1BT9 A;  2ERV A;  4O49 A;  7PRN A;  2XTQ A;  1GFQ A;  3HOE A;  2N2L A;  2LHF A;  3SYS A;  4GCP A;  3SZD A;  4LSE A;  4FMS A;  4O4X A;  4Z3T A;  1MM5 A;  1OSM A;  4GCQ A;  5GV0 A;  5G26 A;  3AA1 A;  4FRX A;  3VZW X;  4AUI A;  4RJX A;  4E1S A;  4FSO A;  4KR4 A;  3POR A;  3POX A;  3AAE B;  2KZ7 A;  3AAA B;  4FZL A;  3AA0 A;  3SZV A;  2GE4 A;  4FT6 A;  4O3Y A;  8PRN A;  3A2S X;  5EE2 A;  2KZ7 B;  2ZFG A;  1IZN A;  3LK3 A;  3FYX A;  3NSG A;  2M06 A;  3LK4 1;  2W80 C;  5D5D A;  2Y0L A;  5DL8 A;  3WI5 A;  4E1T A;  4D65 A;  1IZN B;  3LK3 B;  2YPV A;  4LSF A;  5ADX K;  4O3Z A;  5DL5 A;  4GHB A;  3KVD D;  4O3W A;  2POR A;  3POU A;  2JMM A;  2X27 X;  3HWB A;  2MHL A;  4QQ1 A;  2PRN A;  1G90 A;  1YS5 A;  3AA7 A;  4LSH A;  5ADX L;  3VY8 X;  4D64 A;  2J4U P;  3AAE A;  3AAA A;  4FUV A;  4U9C A;  1BH3 A;  2W81 C;  2XTR A;  3QRC A;  1ZHY A;  4D5U A;  4N59 A;  3AA7 B;  4FZM A;  1ZHZ A;  2KXP B;  4F4B A;  3EMN X;  4LSI A;  5IYU A;  1OPF A;  3GP6 A;  3QRA A;  4PUX A;  2XE2 A;  2ZLD A;  4FES A;  2Y7S A;  2YNK A;  3VE2 A;  5T5F A;  1ZHT A;  4FOZ A;  3VE1 A;  2O4V A;  5DL6 A;  4XNK A;  4AZL A;  2Y0K A;  3LK4 2;  3O0E A;  2XE5 A;  3T0S A;  4B61 A;  4RJW A;  4GCS A;  4AKR A;  3LK2 A;  3PRN A;  3VZU X;  2LFU A;  4RLB A;  2FGQ X;  2N2M A;  2KC0 A;  4GF4 A;  4JCH A;  5FVN A;  3PQS A;  4KR8 A;  5AFU L;  4AKR B;  3SY9 A;  3LK2 B;  3DA4 A;  3K19 A;  1PHO A;  2KXP A;  2FGR A;  1MM4 A;  2XMX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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