4AYNA

Structure of the c-terminal barrel of neisseria meningitidis fhbp variant 2
Total Genus 31
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
125
structure length
125
Chain Sequence
GGEHTAFNQLPSGKAEYHGKAFSSDDPNGRLHYSIDFTKKQGYGRIEHLKTPEQNVELASAELKADEKSHAVILGDTRYGSEEKGTYHLALFGDRAQEIAGSATVKIREKVHEIGIAGKQLEHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
pubmed doi rcsb
molecule tags Immune system
source organism Neisseria meningitidis mc58
molecule keywords FACTOR H-BINDING PROTEIN
total genus 31
structure length 125
sequence length 125
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08794 Lipoprot_C Lipoprotein GNA1870 C terminal like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.90 Mainly Beta Beta Barrel Porin Porin 4aynA00
3VE2A 3VE1A 4AYMC 4O4XA 5EE2A 3UAQA 4AYDC 4O3ZA 2LFUA 2W81C 4AYNA 3V8UA 4O3WA 2Y7SA 5T5FA 2YPVA 4O49A 2KC0A 2W80C 4Z3TA 3PQSA 4O3XB 4O4UA 2KDYA 3KVDD 3PQUA 3HOLA 3HOEA 4U9CA 4AYEC 4O3YA 4QQ1A 1YS5A 4AYID
chains in the Genus database with same CATH superfamily
1BT9A 3VE2A 2R4LA 3DA4A 4FZMA 4KRAA 2R4PA 4G76A 4AYMC 5AFUL 2MNHA 3PF1A 2WVPA 4GF4A 5EE2A 3QRCA 3UAQA 2ODJA 3JCUO 4RLBA 4AYDC 2W81C 3PGUA 5G26A 3AA1B 1HXXA 3A2SX 3PORA 1HXUA 3LK2A 3LK41 3SY9A 4AZLA 4D65A 8PRNA 1BH3A 2PRNA 2JQYA 1Q9GA 5GTIO 2IWWA 4PJ0O 4O49A 4RJXA 5GTHO 5H2FO 2KZ7B 3K19A 1T1LA 2XG6A 3DA3A 4Z3TA 4FQEA 2JMMA 5G3AA 3C5OA 1IZNB 3BRYA 2X9KA 3JTYA 4FESA 3AA7A 3KVDD 4B61A 2KXPB 2LHFA 3PQUA 4C00A 1PHOA 1QJPA 2XE3A 2WJQA 4C69X 2R8AA 3AAEA 5G39A 4D5UA 2R4NA 1YS5A 1GFQA 4XNKA 2Y0LA 3PRNA 3VE1A 5KAIO 3T20A 4N75A 1T16A 5DL6A 4O4XA 4AKRB 4FMSA 2XMXA 2QTKA 2ZLDA 4C4VA 2PORA 4JCHA 5KAFO 3DZMA 3V8UA 3AA6B 3PGRA 4E1SA 3G7GA 4RLCA 1MM5A 4FSOA 2R4OA 2Y7SA 2K4TA 3UU2A 5B66O 3AAAA 4LSEA 5PRNA 3LK3B 3A0HO 1GFPA 2W80C 4JFBA 3TZGA 3AA0A 5D5DA 4O4UA 2N2MA 2KDYA 2IWVA 4N74A 4GHBA 3UPGA 3SYBA 1ZHWA 4U9CA 2AXTO 4FUVA 4D64A 4F4BA 2F1TA 3BS0A 3DWNA 3SYSA 4RJWA 3BRZA 5B5EO 2XE1A 3PGSA 3POUA 3LK2B 5GV0A 3SY7A 2M06A 4LSIA 1ZHTA 2XTQA 2M07A 1THQA 3KZIO 4AYNA 1MM4A 4CTDA 4AFKA 4LSFA 5TISO 1GFMA 1OPFA 4N58A 1PRNA 2O4VA 5T5FA 3AA1A 2YPVA 4E1TA 1ORMA 2J1NA 4IL6O 1E54A 3AA7B 2F1VA 3NJTA 4RL9A 3T24A 3VY8X 5G38A 2YNKA 5E79O 5IYUA 4PUXA 3LK42 1QJ9A 3AAEB 2X27X 1ZHZA 3VY9X 2KZ7A 2WJRA 2FGQX 3HOLA 3RBHA 1BXWA 3HOEA 3NSGA 4XNLA 1QJ8A 1IZNA 1P4TA 3DWOX 2FGRA 2KXPA 1H6S1 4O3YA 4QQ1A 3EMNX 4AYID 4BUMX 1Q9FA 1OSMA 1S5LO 2MHLA 3GP6A 2F1CX 3O0EA 3A0BO 3FYXA 4K3CA 4C4VB 5ADXK 4FZLA 5DL5A 4G75A 4FT6A 2Y2XA 4GCPA 5FVNA 3WI5A 3WI4A 3WU2O 6PRNA 1ZHYA 1HXTA 4FRXA 4O3ZA 2LFUA 4N59A 4UB6O 4GCSA 1G90A 3AAAB 4AKRA 3VZTX 1GFNA 3VZUX 4FZNA 4O3WA 2N2LA 2Y0KA 2Y0HA 4FOZA 3HWBA 1ZHXA 2R88A 2GE4A 4KR4A 2J4UP 4FRTA 5JDPA 4AKMA 3AA0B 4LSHA 4PR7A 4FSPA 2KC0A 3AA6A 5AFUK 5ADXL 5DL8A 3QRAA 2XE2A 5DL7A 3PQSA 2K0LA 3POXA 3LK3A 2R89A 4KR8A 4O3XB 3SZVA 3SZDA 3VZWX 4K3BA 2XTRA 1GFOA 1MPFA 2ZFGA 2OMFA 7PRNA 4GCQA 3T0SA 4AYEC 2ERVA 2XE5A 4UB8O 3HW9A 4AUIA 3POQA
chains in the Genus database with same CATH topology
1BT9A 3VE2A 3DA4A 4FZMA 4KRAA 4G76A 4AYMC 5AFUL 2MNHA 5EE2A 4GF4A 3UAQA 3QRCA 2ODJA 4AYDC 4RLBA 2W81C 5G26A 3AA1B 1HXXA 3A2SX 3PORA 1HXUA 3LK2A 3LK41 3SY9A 4AZLA 4D65A 8PRNA 1BH3A 2PRNA 1Q9GA 4O49A 4RJXA 2KZ7B 3K19A 4Z3TA 2XG6A 3DA3A 2JMMA 3C5OA 1IZNB 3JTYA 4FESA 4B61A 3AA7A 3KVDD 2KXPB 2LHFA 3PQUA 1PHOA 1QJPA 2XE3A 4C69X 3AAEA 4D5UA 1YS5A 1GFQA 4XNKA 2Y0LA 3PRNA 3VE1A 3T20A 5DL6A 4O4XA 4AKRB 4FMSA 2XMXA 2QTKA 2ZLDA 2PORA 4JCHA 3V8UA 3AA6B 4E1SA 3G7GA 4RLCA 1MM5A 4FSOA 2Y7SA 2K4TA 3UU2A 3AAAA 4LSEA 5PRNA 3LK3B 1GFPA 2W80C 4JFBA 3TZGA 3AA0A 5D5DA 4O4UA 2KDYA 2N2MA 4GHBA 3UPGA 3SYBA 1ZHWA 4U9CA 4FUVA 4D64A 4F4BA 2F1TA 3SYSA 4RJWA 2XE1A 3POUA 3LK2B 5GV0A 3SY7A 2M06A 4LSIA 1ZHTA 2XTQA 2M07A 1THQA 4AYNA 1MM4A 4AFKA 4LSFA 1GFMA 1OPFA 4N58A 1PRNA 2O4VA 5T5FA 3AA1A 2YPVA 4E1TA 1ORMA 2J1NA 1E54A 3AA7B 2F1VA 4RL9A 3T24A 3VY8X 2YNKA 5IYUA 4PUXA 3LK42 1QJ9A 3AAEB 2X27X 1ZHZA 3VY9X 2KZ7A 3HOLA 2FGQX 3RBHA 1BXWA 3HOEA 3NSGA 4XNLA 1QJ8A 1IZNA 1P4TA 4O3YA 2FGRA 2KXPA 1H6S1 4QQ1A 4BUMX 3EMNX 4AYID 1Q9FA 1OSMA 2MHLA 3GP6A 3O0EA 5ADXK 3FYXA 4FZLA 5DL5A 4G75A 4FT6A 2Y2XA 4GCPA 5FVNA 3WI5A 3WI4A 6PRNA 1ZHYA 1HXTA 4FRXA 4O3ZA 2LFUA 4N59A 4GCSA 3AAAB 4AKRA 3VZTX 1GFNA 3VZUX 4FZNA 4O3WA 2N2LA 2Y0KA 2Y0HA 4FOZA 3HWBA 1ZHXA 3VZWX 2GE4A 4KR4A 2J4UP 4FRTA 5JDPA 4AKMA 3AA0B 4LSHA 4FSPA 2KC0A 3AA6A 5AFUK 5ADXL 5DL8A 3QRAA 2XE2A 5DL7A 3PQSA 2K0LA 3POXA 3LK3A 4KR8A 4O3XB 3SZVA 3SZDA 1G90A 2XTRA 1GFOA 1MPFA 2ZFGA 2OMFA 7PRNA 4GCQA 3T0SA 4AYEC 2ERVA 2XE5A 3HW9A 4AUIA 3POQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VE2 A;  3VE1 A;  4AYM C;  4O4X A;  5EE2 A;  3UAQ A;  4AYD C;  4O3Z A;  2LFU A;  2W81 C;  4AYN A;  3V8U A;  4O3W A;  2Y7S A;  5T5F A;  2YPV A;  4O49 A;  2KC0 A;  2W80 C;  4Z3T A;  3PQS A;  4O3X B;  4O4U A;  2KDY A;  3KVD D;  3PQU A;  3HOL A;  3HOE A;  4U9C A;  4AYE C;  4O3Y A;  4QQ1 A;  1YS5 A;  4AYI D; 
#chains in the Genus database with same CATH topology
 1BT9 A;  3VE2 A;  2R4L A;  3DA4 A;  4FZM A;  4KRA A;  2R4P A;  4G76 A;  4AYM C;  5AFU L;  2MNH A;  3PF1 A;  2WVP A;  4GF4 A;  5EE2 A;  3QRC A;  3UAQ A;  2ODJ A;  3JCU O;  4RLB A;  4AYD C;  2W81 C;  3PGU A;  5G26 A;  3AA1 B;  1HXX A;  3A2S X;  3POR A;  1HXU A;  3LK2 A;  3LK4 1;  3SY9 A;  4AZL A;  4D65 A;  8PRN A;  1BH3 A;  2PRN A;  2JQY A;  1Q9G A;  5GTI O;  2IWW A;  4PJ0 O;  4O49 A;  4RJX A;  5GTH O;  5H2F O;  2KZ7 B;  3K19 A;  1T1L A;  2XG6 A;  3DA3 A;  4Z3T A;  4FQE A;  2JMM A;  5G3A A;  3C5O A;  1IZN B;  3BRY A;  2X9K A;  3JTY A;  4FES A;  3AA7 A;  3KVD D;  4B61 A;  2KXP B;  2LHF A;  3PQU A;  4C00 A;  1PHO A;  1QJP A;  2XE3 A;  2WJQ A;  4C69 X;  2R8A A;  3AAE A;  5G39 A;  4D5U A;  2R4N A;  1YS5 A;  1GFQ A;  4XNK A;  2Y0L A;  3PRN A;  3VE1 A;  5KAI O;  3T20 A;  4N75 A;  1T16 A;  5DL6 A;  4O4X A;  4AKR B;  4FMS A;  2XMX A;  2QTK A;  2ZLD A;  4C4V A;  2POR A;  4JCH A;  5KAF O;  3DZM A;  3V8U A;  3AA6 B;  3PGR A;  4E1S A;  3G7G A;  4RLC A;  1MM5 A;  4FSO A;  2R4O A;  2Y7S A;  2K4T A;  3UU2 A;  5B66 O;  3AAA A;  4LSE A;  5PRN A;  3LK3 B;  3A0H O;  1GFP A;  2W80 C;  4JFB A;  3TZG A;  3AA0 A;  5D5D A;  4O4U A;  2N2M A;  2KDY A;  2IWV A;  4N74 A;  4GHB A;  3UPG A;  3SYB A;  1ZHW A;  4U9C A;  2AXT O;  4FUV A;  4D64 A;  4F4B A;  2F1T A;  3BS0 A;  3DWN A;  3SYS A;  4RJW A;  3BRZ A;  5B5E O;  2XE1 A;  3PGS A;  3POU A;  3LK2 B;  5GV0 A;  3SY7 A;  2M06 A;  4LSI A;  1ZHT A;  2XTQ A;  2M07 A;  1THQ A;  3KZI O;  4AYN A;  1MM4 A;  4CTD A;  4AFK A;  4LSF A;  5TIS O;  1GFM A;  1OPF A;  4N58 A;  1PRN A;  2O4V A;  5T5F A;  3AA1 A;  2YPV A;  4E1T A;  1ORM A;  2J1N A;  4IL6 O;  1E54 A;  3AA7 B;  2F1V A;  3NJT A;  4RL9 A;  3T24 A;  3VY8 X;  5G38 A;  2YNK A;  5E79 O;  5IYU A;  4PUX A;  3LK4 2;  1QJ9 A;  3AAE B;  2X27 X;  1ZHZ A;  3VY9 X;  2KZ7 A;  2WJR A;  2FGQ X;  3HOL A;  3RBH A;  1BXW A;  3HOE A;  3NSG A;  4XNL A;  1QJ8 A;  1IZN A;  1P4T A;  3DWO X;  2FGR A;  2KXP A;  1H6S 1;  4O3Y A;  4QQ1 A;  3EMN X;  4AYI D;  4BUM X;  1Q9F A;  1OSM A;  1S5L O;  2MHL A;  3GP6 A;  2F1C X;  3O0E A;  3A0B O;  3FYX A;  4K3C A;  4C4V B;  5ADX K;  4FZL A;  5DL5 A;  4G75 A;  4FT6 A;  2Y2X A;  4GCP A;  5FVN A;  3WI5 A;  3WI4 A;  3WU2 O;  6PRN A;  1ZHY A;  1HXT A;  4FRX A;  4O3Z A;  2LFU A;  4N59 A;  4UB6 O;  4GCS A;  1G90 A;  3AAA B;  4AKR A;  3VZT X;  1GFN A;  3VZU X;  4FZN A;  4O3W A;  2N2L A;  2Y0K A;  2Y0H A;  4FOZ A;  3HWB A;  1ZHX A;  2R88 A;  2GE4 A;  4KR4 A;  2J4U P;  4FRT A;  5JDP A;  4AKM A;  3AA0 B;  4LSH A;  4PR7 A;  4FSP A;  2KC0 A;  3AA6 A;  5AFU K;  5ADX L;  5DL8 A;  3QRA A;  2XE2 A;  5DL7 A;  3PQS A;  2K0L A;  3POX A;  3LK3 A;  2R89 A;  4KR8 A;  4O3X B;  3SZV A;  3SZD A;  3VZW X;  4K3B A;  2XTR A;  1GFO A;  1MPF A;  2ZFG A;  2OMF A;  7PRN A;  4GCQ A;  3T0S A;  4AYE C;  2ERV A;  2XE5 A;  4UB8 O;  3HW9 A;  4AUI A;  3POQ A; 
#chains in the Genus database with same CATH homology
 1BT9 A;  3VE2 A;  3DA4 A;  4FZM A;  4KRA A;  4G76 A;  4AYM C;  5AFU L;  2MNH A;  5EE2 A;  4GF4 A;  3UAQ A;  3QRC A;  2ODJ A;  4AYD C;  4RLB A;  2W81 C;  5G26 A;  3AA1 B;  1HXX A;  3A2S X;  3POR A;  1HXU A;  3LK2 A;  3LK4 1;  3SY9 A;  4AZL A;  4D65 A;  8PRN A;  1BH3 A;  2PRN A;  1Q9G A;  4O49 A;  4RJX A;  2KZ7 B;  3K19 A;  4Z3T A;  2XG6 A;  3DA3 A;  2JMM A;  3C5O A;  1IZN B;  3JTY A;  4FES A;  4B61 A;  3AA7 A;  3KVD D;  2KXP B;  2LHF A;  3PQU A;  1PHO A;  1QJP A;  2XE3 A;  4C69 X;  3AAE A;  4D5U A;  1YS5 A;  1GFQ A;  4XNK A;  2Y0L A;  3PRN A;  3VE1 A;  3T20 A;  5DL6 A;  4O4X A;  4AKR B;  4FMS A;  2XMX A;  2QTK A;  2ZLD A;  2POR A;  4JCH A;  3V8U A;  3AA6 B;  4E1S A;  3G7G A;  4RLC A;  1MM5 A;  4FSO A;  2Y7S A;  2K4T A;  3UU2 A;  3AAA A;  4LSE A;  5PRN A;  3LK3 B;  1GFP A;  2W80 C;  4JFB A;  3TZG A;  3AA0 A;  5D5D A;  4O4U A;  2KDY A;  2N2M A;  4GHB A;  3UPG A;  3SYB A;  1ZHW A;  4U9C A;  4FUV A;  4D64 A;  4F4B A;  2F1T A;  3SYS A;  4RJW A;  2XE1 A;  3POU A;  3LK2 B;  5GV0 A;  3SY7 A;  2M06 A;  4LSI A;  1ZHT A;  2XTQ A;  2M07 A;  1THQ A;  4AYN A;  1MM4 A;  4AFK A;  4LSF A;  1GFM A;  1OPF A;  4N58 A;  1PRN A;  2O4V A;  5T5F A;  3AA1 A;  2YPV A;  4E1T A;  1ORM A;  2J1N A;  1E54 A;  3AA7 B;  2F1V A;  4RL9 A;  3T24 A;  3VY8 X;  2YNK A;  5IYU A;  4PUX A;  3LK4 2;  1QJ9 A;  3AAE B;  2X27 X;  1ZHZ A;  3VY9 X;  2KZ7 A;  3HOL A;  2FGQ X;  3RBH A;  1BXW A;  3HOE A;  3NSG A;  4XNL A;  1QJ8 A;  1IZN A;  1P4T A;  4O3Y A;  2FGR A;  2KXP A;  1H6S 1;  4QQ1 A;  4BUM X;  3EMN X;  4AYI D;  1Q9F A;  1OSM A;  2MHL A;  3GP6 A;  3O0E A;  5ADX K;  3FYX A;  4FZL A;  5DL5 A;  4G75 A;  4FT6 A;  2Y2X A;  4GCP A;  5FVN A;  3WI5 A;  3WI4 A;  6PRN A;  1ZHY A;  1HXT A;  4FRX A;  4O3Z A;  2LFU A;  4N59 A;  4GCS A;  3AAA B;  4AKR A;  3VZT X;  1GFN A;  3VZU X;  4FZN A;  4O3W A;  2N2L A;  2Y0K A;  2Y0H A;  4FOZ A;  3HWB A;  1ZHX A;  3VZW X;  2GE4 A;  4KR4 A;  2J4U P;  4FRT A;  5JDP A;  4AKM A;  3AA0 B;  4LSH A;  4FSP A;  2KC0 A;  3AA6 A;  5AFU K;  5ADX L;  5DL8 A;  3QRA A;  2XE2 A;  5DL7 A;  3PQS A;  2K0L A;  3POX A;  3LK3 A;  4KR8 A;  4O3X B;  3SZV A;  3SZD A;  1G90 A;  2XTR A;  1GFO A;  1MPF A;  2ZFG A;  2OMF A;  7PRN A;  4GCQ A;  3T0S A;  4AYE C;  2ERV A;  2XE5 A;  3HW9 A;  4AUI A;  3POQ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...