5GV0 | Genus

Total Genus 35

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	35
sequence length	162
structure length	162
Chain Sequence	DPTVSKYNVTGNNGTCLLASMALQLNITYLKKDNKTVTRAFNISPNDTSSGSCGINLVTLKVENKNRALELQFGMNASSSLFFLQGVRLNMTLPDALVPTFSISNHSLKALQATVGNSYKCNTEEHIFVSKMLSLNVFSVQVQAFKVDSDRFGSVEECVQDG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Membrane protein
source organism	Mus musculus
publication title	Lysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2) assemble via distinct modes pubmed doi rcsb
molecule keywords	Lysosome-associated membrane glycoprotein 1
total genus	35
structure length	162
sequence length	162
ec nomenclature
pdb deposition date	2016-09-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01299	Lamp	Lysosome-associated membrane glycoprotein (Lamp)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.40.160.110	Mainly Beta	Beta Barrel	Porin	Porin	5gv0A00

5GV0A 4AKMA
chains in the Genus database with same CATH superfamily

3LK3A 2O4VA 3PQSA 5E79O 2Y0KA 2ZLDA 1HXUA 4AYNA 4C69X 1IZNA 3LK41 4FOZA 2F1CX 4AZLA 3A2SX 3AA6A 3NSGA 3A0BO 4O4XA 2K0LA 2W80C 3VE1A 2YPVA 4F4BA 2KZ7B 4LSFA 3PORA 4O49A 4D5UA 5GTHO 3AA7B 1OPFA 5DL6A 3DZMA 2GE4A 4G75A 2WJQA 2IWWA 2FGRA 2XE5A 4AUIA 1GFMA 2YNKA 3DA4A 3LK2A 5GV0A 4XNLA 3C5OA 4GHBA 4G76A 3JTYA 4FZNA 2LFUA 2M06A 2R4OA 4FESA 4KRAA 2Y0LA 5DL7A 4PJ0O 5DL5A 4FRXA 1MM5A 5AFUL 1ZHYA 3AAAB 2KXPB 3UAQA 1T1LA 3VZTX 3DWOX 1T16A 3AA1A 1IZNB 3UU2A 2R4PA 4AKRB 4UB6O 3FYXA 1ZHXA 3AA6B 2XG6A 4IL6O 1PRNA 2LHFA 2R88A 5KAFO 3PRNA 4E1TA 1MPFA 3HOLA 3AA0A 4QQ1A 1GFQA 2ERVA 4O3ZA 5G38A 3PF1A 4FUVA 4RL9A 4AKMA 1H6S1 1BXWA 4FMSA 3SYBA 6PRNA 3POUA 2PRNA 1GFOA 3T0SA 4BUMX 1ZHTA 5AFUK 2R4NA 5TISO 5G3AA 4O3XB 3WU2O 4UB8O 4AYDC 1E54A 2R8AA 2X9KA 4N75A 3PGSA 4AFKA 5IYUA 2QTKA 5PRNA 4PR7A 2OMFA 5D5DA 1P4TA 2KDYA 5ADXL 2WJRA 2ODJA 4FZLA 4FQEA 4B61A 1QJPA 3K19A 2F1TA 4FZMA 3LK42 3VY9X 3LK3B 2XTRA 3V8UA 3PQUA 4FT6A 5B5EO 7PRNA 2JMMA 4D64A 3RBHA 4C00A 2J4UP 8PRNA 3AA0B 1G90A 4O4UA 4K3BA 5JDPA 2N2MA 4N58A 3TZGA 4AYID 1OSMA 4XNKA 3AAEA 4RLCA 4N59A 3VY8X 4GCPA 2IWVA 3BS0A 3SY7A 4O3WA 4JCHA 1BT9A 4FRTA 3QRCA 5FVNA 3VZWX 3WI4A 4C4VA 1S5LO 1GFPA 3LK2B 1ORMA 3VZUX 2XE3A 4U9CA 3SYSA 3UPGA 3BRZA 3HW9A 2K4TA 3DA3A 3SZDA 5ADXK 1Q9FA 4Z3TA 3PGUA 1Q9GA 3SZVA 2WVPA 3G7GA 3SY9A 1THQA 2M07A 3QRAA 5DL8A 2R4LA 3AA1B 4JFBA 4LSHA 3VE2A 4AYEC 5EE2A 2JQYA 4GCQA 1BH3A 4RJXA 5KAIO 4E1SA 2R89A 1YS5A 2XE2A 2W81C 4GCSA 4AKRA 4KR4A 1QJ9A 4FSOA 3AAEB 5GTIO 1GFNA 3KVDD 5B66O 2X27X 2Y2XA 4RJWA 4RLBA 4N74A 1PHOA 2KC0A 3POXA 5G26A 4CTDA 4D65A 4O3YA 3GP6A 3POQA 4C4VB 2XE1A 3BRYA 3WI5A 4K3CA 5T5FA 2XTQA 3HOEA 5H2FO 1QJ8A 2XMXA 3JCUO 3NJTA 3EMNX 1MM4A 2KZ7A 5G39A 4KR8A 2Y7SA 3A0HO 3AA7A 2Y0HA 2MHLA 2ZFGA 1ZHZA 3PGRA 4LSEA 3KZIO 1ZHWA 2F1VA 4GF4A 1HXXA 3HWBA 4LSIA 4FSPA 3DWNA 4PUXA 3T24A 3T20A 2J1NA 2FGQX 2AXTO 2MNHA 3O0EA 4AYMC 3AAAA 1HXTA 2PORA 2KXPA 2N2LA
chains in the Genus database with same CATH topology

3LK3A 2O4VA 3PQSA 4AYNA 2Y0KA 2ZLDA 1HXUA 4C69X 1IZNA 3LK41 4FOZA 4AZLA 3A2SX 3AA6A 3NSGA 4O4XA 2K0LA 2W80C 3VE1A 2YPVA 4F4BA 2KZ7B 4LSFA 3PORA 4O49A 4D5UA 3AA7B 1OPFA 5DL6A 2GE4A 4G75A 2FGRA 2XE5A 4AUIA 1GFMA 2YNKA 3DA4A 3LK2A 5GV0A 4XNLA 3C5OA 4GHBA 4G76A 3JTYA 4FZNA 2LFUA 2M06A 4FESA 4KRAA 2Y0LA 5DL7A 5DL5A 4FRXA 1MM5A 5AFUL 1ZHYA 3AAAB 2KXPB 3UAQA 3VZTX 3AA1A 1IZNB 3UU2A 4AKRB 3FYXA 1ZHXA 3AA6B 2XG6A 1PRNA 2LHFA 3PRNA 4E1TA 1MPFA 3HOLA 3AA0A 4QQ1A 1GFQA 2ERVA 4O3ZA 4FUVA 4RL9A 4AKMA 1H6S1 1BXWA 4FMSA 3SYBA 6PRNA 3POUA 2PRNA 1GFOA 3T0SA 4BUMX 1ZHTA 5AFUK 4O3XB 4AYDC 1E54A 4AFKA 5IYUA 2QTKA 5PRNA 2OMFA 5D5DA 1P4TA 2KDYA 5ADXL 2ODJA 4FZLA 4B61A 1QJPA 3K19A 2F1TA 4FZMA 3LK42 3VY9X 3LK3B 2XTRA 3V8UA 3PQUA 4FT6A 7PRNA 2JMMA 4D64A 3RBHA 2J4UP 8PRNA 3AA0B 1G90A 4O4UA 5JDPA 2N2MA 4N58A 3TZGA 4AYID 1OSMA 4XNKA 3AAEA 4RLCA 4N59A 3VY8X 4GCPA 3SY7A 4O3WA 4JCHA 1BT9A 4FRTA 3QRCA 5FVNA 3VZWX 3WI4A 3UPGA 1GFPA 3LK2B 1ORMA 3VZUX 2XE3A 4U9CA 3SYSA 3HW9A 2K4TA 3DA3A 3SZDA 5ADXK 1Q9FA 4Z3TA 1Q9GA 3SZVA 3G7GA 3SY9A 1THQA 2M07A 3QRAA 5DL8A 3VE2A 3AA1B 4JFBA 4LSHA 4AYEC 5EE2A 4GCQA 1BH3A 4RJXA 4E1SA 1YS5A 2XE2A 2W81C 4GCSA 4AKRA 4KR4A 1QJ9A 4FSOA 3AAEB 1GFNA 3KVDD 2X27X 2Y2XA 4RJWA 4RLBA 1PHOA 2KC0A 3POXA 5G26A 4D65A 4O3YA 3GP6A 3POQA 2XE1A 3WI5A 5T5FA 2XTQA 3HOEA 1QJ8A 2XMXA 3EMNX 1MM4A 2KZ7A 4KR8A 2Y7SA 3AA7A 2Y0HA 2MHLA 2ZFGA 1ZHZA 4LSEA 1ZHWA 2F1VA 4GF4A 1HXXA 3HWBA 4LSIA 4FSPA 4PUXA 3T24A 3T20A 2J1NA 2FGQX 2MNHA 3O0EA 4AYMC 3AAAA 1HXTA 2PORA 2KXPA 2N2LA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 5GV0 A;  4AKM A; 
#chains in the Genus database with same CATH topology
 3LK3 A;  2O4V A;  3PQS A;  5E79 O;  2Y0K A;  2ZLD A;  1HXU A;  4AYN A;  4C69 X;  1IZN A;  3LK4 1;  4FOZ A;  2F1C X;  4AZL A;  3A2S X;  3AA6 A;  3NSG A;  3A0B O;  4O4X A;  2K0L A;  2W80 C;  3VE1 A;  2YPV A;  4F4B A;  2KZ7 B;  4LSF A;  3POR A;  4O49 A;  4D5U A;  5GTH O;  3AA7 B;  1OPF A;  5DL6 A;  3DZM A;  2GE4 A;  4G75 A;  2WJQ A;  2IWW A;  2FGR A;  2XE5 A;  4AUI A;  1GFM A;  2YNK A;  3DA4 A;  3LK2 A;  5GV0 A;  4XNL A;  3C5O A;  4GHB A;  4G76 A;  3JTY A;  4FZN A;  2LFU A;  2M06 A;  2R4O A;  4FES A;  4KRA A;  2Y0L A;  5DL7 A;  4PJ0 O;  5DL5 A;  4FRX A;  1MM5 A;  5AFU L;  1ZHY A;  3AAA B;  2KXP B;  3UAQ A;  1T1L A;  3VZT X;  3DWO X;  1T16 A;  3AA1 A;  1IZN B;  3UU2 A;  2R4P A;  4AKR B;  4UB6 O;  3FYX A;  1ZHX A;  3AA6 B;  2XG6 A;  4IL6 O;  1PRN A;  2LHF A;  2R88 A;  5KAF O;  3PRN A;  4E1T A;  1MPF A;  3HOL A;  3AA0 A;  4QQ1 A;  1GFQ A;  2ERV A;  4O3Z A;  5G38 A;  3PF1 A;  4FUV A;  4RL9 A;  4AKM A;  1H6S 1;  1BXW A;  4FMS A;  3SYB A;  6PRN A;  3POU A;  2PRN A;  1GFO A;  3T0S A;  4BUM X;  1ZHT A;  5AFU K;  2R4N A;  5TIS O;  5G3A A;  4O3X B;  3WU2 O;  4UB8 O;  4AYD C;  1E54 A;  2R8A A;  2X9K A;  4N75 A;  3PGS A;  4AFK A;  5IYU A;  2QTK A;  5PRN A;  4PR7 A;  2OMF A;  5D5D A;  1P4T A;  2KDY A;  5ADX L;  2WJR A;  2ODJ A;  4FZL A;  4FQE A;  4B61 A;  1QJP A;  3K19 A;  2F1T A;  4FZM A;  3LK4 2;  3VY9 X;  3LK3 B;  2XTR A;  3V8U A;  3PQU A;  4FT6 A;  5B5E O;  7PRN A;  2JMM A;  4D64 A;  3RBH A;  4C00 A;  2J4U P;  8PRN A;  3AA0 B;  1G90 A;  4O4U A;  4K3B A;  5JDP A;  2N2M A;  4N58 A;  3TZG A;  4AYI D;  1OSM A;  4XNK A;  3AAE A;  4RLC A;  4N59 A;  3VY8 X;  4GCP A;  2IWV A;  3BS0 A;  3SY7 A;  4O3W A;  4JCH A;  1BT9 A;  4FRT A;  3QRC A;  5FVN A;  3VZW X;  3WI4 A;  4C4V A;  1S5L O;  1GFP A;  3LK2 B;  1ORM A;  3VZU X;  2XE3 A;  4U9C A;  3SYS A;  3UPG A;  3BRZ A;  3HW9 A;  2K4T A;  3DA3 A;  3SZD A;  5ADX K;  1Q9F A;  4Z3T A;  3PGU A;  1Q9G A;  3SZV A;  2WVP A;  3G7G A;  3SY9 A;  1THQ A;  2M07 A;  3QRA A;  5DL8 A;  2R4L A;  3AA1 B;  4JFB A;  4LSH A;  3VE2 A;  4AYE C;  5EE2 A;  2JQY A;  4GCQ A;  1BH3 A;  4RJX A;  5KAI O;  4E1S A;  2R89 A;  1YS5 A;  2XE2 A;  2W81 C;  4GCS A;  4AKR A;  4KR4 A;  1QJ9 A;  4FSO A;  3AAE B;  5GTI O;  1GFN A;  3KVD D;  5B66 O;  2X27 X;  2Y2X A;  4RJW A;  4RLB A;  4N74 A;  1PHO A;  2KC0 A;  3POX A;  5G26 A;  4CTD A;  4D65 A;  4O3Y A;  3GP6 A;  3POQ A;  4C4V B;  2XE1 A;  3BRY A;  3WI5 A;  4K3C A;  5T5F A;  2XTQ A;  3HOE A;  5H2F O;  1QJ8 A;  2XMX A;  3JCU O;  3NJT A;  3EMN X;  1MM4 A;  2KZ7 A;  5G39 A;  4KR8 A;  2Y7S A;  3A0H O;  3AA7 A;  2Y0H A;  2MHL A;  2ZFG A;  1ZHZ A;  3PGR A;  4LSE A;  3KZI O;  1ZHW A;  2F1V A;  4GF4 A;  1HXX A;  3HWB A;  4LSI A;  4FSP A;  3DWN A;  4PUX A;  3T24 A;  3T20 A;  2J1N A;  2FGQ X;  2AXT O;  2MNH A;  3O0E A;  4AYM C;  3AAA A;  1HXT A;  2POR A;  2KXP A;  2N2L A; 
#chains in the Genus database with same CATH homology
 3LK3 A;  2O4V A;  3PQS A;  4AYN A;  2Y0K A;  2ZLD A;  1HXU A;  4C69 X;  1IZN A;  3LK4 1;  4FOZ A;  4AZL A;  3A2S X;  3AA6 A;  3NSG A;  4O4X A;  2K0L A;  2W80 C;  3VE1 A;  2YPV A;  4F4B A;  2KZ7 B;  4LSF A;  3POR A;  4O49 A;  4D5U A;  3AA7 B;  1OPF A;  5DL6 A;  2GE4 A;  4G75 A;  2FGR A;  2XE5 A;  4AUI A;  1GFM A;  2YNK A;  3DA4 A;  3LK2 A;  5GV0 A;  4XNL A;  3C5O A;  4GHB A;  4G76 A;  3JTY A;  4FZN A;  2LFU A;  2M06 A;  4FES A;  4KRA A;  2Y0L A;  5DL7 A;  5DL5 A;  4FRX A;  1MM5 A;  5AFU L;  1ZHY A;  3AAA B;  2KXP B;  3UAQ A;  3VZT X;  3AA1 A;  1IZN B;  3UU2 A;  4AKR B;  3FYX A;  1ZHX A;  3AA6 B;  2XG6 A;  1PRN A;  2LHF A;  3PRN A;  4E1T A;  1MPF A;  3HOL A;  3AA0 A;  4QQ1 A;  1GFQ A;  2ERV A;  4O3Z A;  4FUV A;  4RL9 A;  4AKM A;  1H6S 1;  1BXW A;  4FMS A;  3SYB A;  6PRN A;  3POU A;  2PRN A;  1GFO A;  3T0S A;  4BUM X;  1ZHT A;  5AFU K;  4O3X B;  4AYD C;  1E54 A;  4AFK A;  5IYU A;  2QTK A;  5PRN A;  2OMF A;  5D5D A;  1P4T A;  2KDY A;  5ADX L;  2ODJ A;  4FZL A;  4B61 A;  1QJP A;  3K19 A;  2F1T A;  4FZM A;  3LK4 2;  3VY9 X;  3LK3 B;  2XTR A;  3V8U A;  3PQU A;  4FT6 A;  7PRN A;  2JMM A;  4D64 A;  3RBH A;  2J4U P;  8PRN A;  3AA0 B;  1G90 A;  4O4U A;  5JDP A;  2N2M A;  4N58 A;  3TZG A;  4AYI D;  1OSM A;  4XNK A;  3AAE A;  4RLC A;  4N59 A;  3VY8 X;  4GCP A;  3SY7 A;  4O3W A;  4JCH A;  1BT9 A;  4FRT A;  3QRC A;  5FVN A;  3VZW X;  3WI4 A;  3UPG A;  1GFP A;  3LK2 B;  1ORM A;  3VZU X;  2XE3 A;  4U9C A;  3SYS A;  3HW9 A;  2K4T A;  3DA3 A;  3SZD A;  5ADX K;  1Q9F A;  4Z3T A;  1Q9G A;  3SZV A;  3G7G A;  3SY9 A;  1THQ A;  2M07 A;  3QRA A;  5DL8 A;  3VE2 A;  3AA1 B;  4JFB A;  4LSH A;  4AYE C;  5EE2 A;  4GCQ A;  1BH3 A;  4RJX A;  4E1S A;  1YS5 A;  2XE2 A;  2W81 C;  4GCS A;  4AKR A;  4KR4 A;  1QJ9 A;  4FSO A;  3AAE B;  1GFN A;  3KVD D;  2X27 X;  2Y2X A;  4RJW A;  4RLB A;  1PHO A;  2KC0 A;  3POX A;  5G26 A;  4D65 A;  4O3Y A;  3GP6 A;  3POQ A;  2XE1 A;  3WI5 A;  5T5F A;  2XTQ A;  3HOE A;  1QJ8 A;  2XMX A;  3EMN X;  1MM4 A;  2KZ7 A;  4KR8 A;  2Y7S A;  3AA7 A;  2Y0H A;  2MHL A;  2ZFG A;  1ZHZ A;  4LSE A;  1ZHW A;  2F1V A;  4GF4 A;  1HXX A;  3HWB A;  4LSI A;  4FSP A;  4PUX A;  3T24 A;  3T20 A;  2J1N A;  2FGQ X;  2MNH A;  3O0E A;  4AYM C;  3AAA A;  1HXT A;  2POR A;  2KXP A;  2N2L A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5GV0A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations