5JDPA

E73v mutant of the human voltage-dependent anion channel
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
285
structure length
285
Chain Sequence
SAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTVKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQARS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-Resolution NMR Determination of the Dynamic Structure of Membrane Proteins.
pubmed doi rcsb
molecule tags Membrane protein
source organism Homo sapiens
molecule keywords Voltage-dependent anion-selective channel protein 1
total genus 56
structure length 285
sequence length 285
ec nomenclature
pdb deposition date 2016-04-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 5jdpA00
5PRNA 1GFQA 3JTYA 2XE2A 3HWBA 2Y2XA 4GCPA 1MPFA 3POQA 3SZDA 4GCQA 2Y0HA 4JFBA 4LSHA 5DL6A 3SY7A 3NSGA 3T24A 3SZVA 3WI4A 3VY8X 4RJXA 3FYXA 3T20A 4FMSA 4LSFA 3T0SA 1GFOA 2ZLDA 3VY9X 1H6S1 3UU2A 4FSOA 3VZTX 3SY9A 2ZFGA 3HW9A 1HXXA 3SYSA 5JDPA 3VZUX 4BUMX 1GFNA 2OMFA 2J4UP 8PRNA 3K19A 1BH3A 3UPGA 2FGRA 2ODJA 4KR4A 3O0EA 3VZWX 4FSPA 1OPFA 4LSIA 3PORA 2O4VA 4RJWA 5DL8A 4GCSA 4FRXA 1GFMA 6PRNA 4KR8A 3WI5A 4D5UA 2XE5A 2PORA 4FT6A 2J1NA 5FVNA 4AUIA 3POUA 3EMNX 3POXA 1BT9A 1E54A 2FGQX 2XE3A 3A2SX 1PRNA 5DL5A 3SYBA 4KRAA 4FOZA 4D65A 4FRTA 2K4TA 1HXUA 1GFPA 2Y0KA 1OSMA 7PRNA 4C69X 2Y0LA 2XG6A 4D64A 2XE1A 5DL7A 1HXTA 4LSEA 1PHOA 2PRNA 3PRNA 2QTKA
chains in the Genus database with same CATH superfamily
3NJTA 1QJ8A 4FESA 4N59A 2X9KA 4GHBA 1Q9GA 5PRNA 1GFQA 2XMXA 3JTYA 2XE2A 3HWBA 5G3AA 2W80C 4U9CA 2Y2XA 4GCPA 4N58A 3G7GA 3KZIO 1MPFA 3HOLA 2LFUA 1S5LO 1ZHWA 3A0BO 3AA7A 1T1LA 3JCUO 3PF1A 3POQA 3SZDA 3TZGA 4GCQA 2Y0HA 1P4TA 3C5OA 3DZMA 2W81C 3UAQA 4AYEC 4JFBA 4LSHA 5DL6A 4K3BA 4QQ1A 2IWWA 3SY7A 3NSGA 3T24A 1T16A 3SZVA 3PQSA 4PUXA 3WI4A 2F1CX 2KZ7A 4RJXA 3VY8X 3FYXA 4O4UA 2R4PA 4G75A 4B61A 3T20A 1QJ9A 4FMSA 4LSFA 4UB6O 3T0SA 3AAEA 5KAFO 3VE1A 1GFOA 2XTRA 2ZLDA 3VY9X 2F1VA 5EE2A 1H6S1 3AA7B 3UU2A 2XTQA 2KDYA 4FSOA 2JMMA 4AYNA 4Z3TA 4RLCA 4C4VA 5E79O 4UB8O 3VZTX 5G39A 3SY9A 2ZFGA 3HW9A 1HXXA 4O3ZA 3SYSA 2JQYA 5JDPA 4FZNA 1ZHXA 3VZUX 2R4NA 2N2LA 5GV0A 1G90A 3PQUA 1GFNA 4AZLA 3AA6A 1BXWA 4BUMX 2OMFA 3PGSA 2KZ7B 2J4UP 2MNHA 2KC0A 2WJQA 3LK2A 5G26A 8PRNA 1MM5A 1YS5A 4FZLA 2N2MA 5KAIO 3K19A 1BH3A 3AAEB 2KXPA 3UPGA 2AXTO 4AFKA 4AKRA 3GP6A 2FGRA 2R89A 2M07A 2ODJA 3DWNA 4O3YA 4KR4A 4FUVA 4E1TA 3O0EA 3VZWX 4C00A 4CTDA 2GE4A 3QRAA 3DA4A 4FSPA 4C4VB 2F1TA 1OPFA 2R88A 4LSIA 5IYUA 3PORA 3DA3A 2O4VA 4RJWA 5DL8A 3BRYA 4GCSA 4FRXA 1GFMA 4E1SA 5ADXL 5B5EO 3AA6B 4F4BA 6PRNA 3A0HO 2YPVA 4KR8A 3WI5A 4AYMC 4D5UA 5AFUL 2XE5A 4O49A 2MHLA 4O4XA 2PORA 4PR7A 2Y7SA 1IZNA 1MM4A 3LK2B 4FT6A 2J1NA 5B66O 3AAAB 5GTIO 3QRCA 5FVNA 2KXPB 2M06A 3BRZA 4AUIA 2YNKA 2R4OA 3POUA 4N74A 4AKRB 4PJ0O 3EMNX 3AAAA 2R8AA 3AA0A 3LK3B 5G38A 3KVDD 3VE2A 5H2FO 3POXA 1BT9A 3AA1A 3HOEA 3LK42 1QJPA 1E54A 2FGQX 3BS0A 4FZMA 5T5FA 3RBHA 4AYDC 3LK3A 2WVPA 5AFUK 2XE3A 2X27X 3A2SX 1PRNA 5DL5A 5GTHO 3SYBA 4AYID 4KRAA 4FOZA 4G76A 4RLBA 1ORMA 1ZHYA 4O3WA 2K0LA 4K3CA 5D5DA 4AKMA 3PGRA 2R4LA 4FRTA 2K4TA 1IZNB 4D65A 3LK41 1HXUA 4IL6O 4JCHA 2IWVA 2ERVA 1GFPA 2Y0KA 3DWOX 4FQEA 4RL9A 1OSMA 3WU2O 4XNLA 4C69X 7PRNA 1ZHZA 5TISO 2Y0LA 2XG6A 4O3XB 4XNKA 4D64A 2XE1A 3AA0B 3V8UA 1Q9FA 3PGUA 5ADXK 5DL7A 1HXTA 3AA1B 4LSEA 1PHOA 1ZHTA 2PRNA 3PRNA 4GF4A 4N75A 2LHFA 2QTKA 1THQA 2WJRA
chains in the Genus database with same CATH topology
4FESA 1QJ8A 4N59A 4GHBA 1Q9GA 5PRNA 1GFQA 2XMXA 3JTYA 2XE2A 3HWBA 2W80C 4U9CA 2Y2XA 4GCPA 4N58A 3G7GA 1MPFA 3HOLA 2LFUA 1ZHWA 3AA7A 3POQA 3SZDA 3TZGA 4GCQA 2Y0HA 1P4TA 3C5OA 3UAQA 2W81C 4AYEC 4JFBA 4LSHA 5DL6A 4QQ1A 3SY7A 3NSGA 3T24A 3SZVA 3PQSA 4PUXA 3WI4A 3VY8X 2KZ7A 4RJXA 3FYXA 4O4UA 4G75A 4B61A 3T20A 1QJ9A 4FMSA 4LSFA 3T0SA 3AAEA 3VE1A 1GFOA 2XTRA 2ZLDA 3VY9X 2F1VA 5EE2A 1H6S1 3AA7B 3UU2A 2XTQA 2KDYA 4FSOA 2JMMA 4AYNA 4Z3TA 4RLCA 3VZTX 3SY9A 2ZFGA 3HW9A 1HXXA 4O3ZA 3SYSA 5JDPA 4FZNA 1ZHXA 3VZUX 1G90A 2N2LA 5GV0A 3PQUA 1GFNA 4AZLA 3AA6A 1BXWA 4BUMX 2OMFA 2KZ7B 2J4UP 2MNHA 2KC0A 3LK2A 5G26A 8PRNA 1MM5A 1YS5A 4FZLA 2N2MA 3K19A 1BH3A 3AAEB 2KXPA 3UPGA 4AFKA 4AKRA 3GP6A 2FGRA 2M07A 2ODJA 4O3YA 4KR4A 4FUVA 4E1TA 3O0EA 3VZWX 2GE4A 3QRAA 3DA4A 4FSPA 5IYUA 2F1TA 1OPFA 4LSIA 3PORA 3DA3A 2O4VA 4RJWA 5DL8A 4GCSA 4FRXA 1GFMA 4E1SA 5ADXL 6PRNA 3AA6B 4F4BA 2YPVA 4KR8A 3WI5A 4AYMC 4D5UA 5AFUL 2XE5A 4O49A 2MHLA 4O4XA 2PORA 2Y7SA 1IZNA 1MM4A 3LK2B 4FT6A 2J1NA 3AAAB 3QRCA 5FVNA 2KXPB 2M06A 4AUIA 2YNKA 3POUA 4AKRB 3EMNX 3AAAA 3AA0A 3LK3B 3VE2A 3KVDD 3POXA 1BT9A 3AA1A 3HOEA 3LK42 1QJPA 1E54A 2FGQX 4FZMA 5T5FA 3RBHA 4AYDC 3LK3A 5AFUK 2XE3A 2X27X 3A2SX 1PRNA 5DL5A 3SYBA 4AYID 4KRAA 4FOZA 4G76A 4RLBA 1ORMA 1ZHYA 4O3WA 2K0LA 5D5DA 4AKMA 4D65A 4FRTA 2K4TA 1IZNB 3LK41 1HXUA 4JCHA 2ERVA 1GFPA 2Y0KA 4RL9A 1OSMA 7PRNA 4XNLA 4C69X 1ZHZA 2Y0LA 2XG6A 4O3XB 4XNKA 4D64A 2XE1A 3AA0B 3V8UA 1Q9FA 5ADXK 5DL7A 1HXTA 3AA1B 4LSEA 1PHOA 1ZHTA 2PRNA 3PRNA 4GF4A 2LHFA 2QTKA 1THQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5PRN A;  1GFQ A;  3JTY A;  2XE2 A;  3HWB A;  2Y2X A;  4GCP A;  1MPF A;  3POQ A;  3SZD A;  4GCQ A;  2Y0H A;  4JFB A;  4LSH A;  5DL6 A;  3SY7 A;  3NSG A;  3T24 A;  3SZV A;  3WI4 A;  3VY8 X;  4RJX A;  3FYX A;  3T20 A;  4FMS A;  4LSF A;  3T0S A;  1GFO A;  2ZLD A;  3VY9 X;  1H6S 1;  3UU2 A;  4FSO A;  3VZT X;  3SY9 A;  2ZFG A;  3HW9 A;  1HXX A;  3SYS A;  5JDP A;  3VZU X;  4BUM X;  1GFN A;  2OMF A;  2J4U P;  8PRN A;  3K19 A;  1BH3 A;  3UPG A;  2FGR A;  2ODJ A;  4KR4 A;  3O0E A;  3VZW X;  4FSP A;  1OPF A;  4LSI A;  3POR A;  2O4V A;  4RJW A;  5DL8 A;  4GCS A;  4FRX A;  1GFM A;  6PRN A;  4KR8 A;  3WI5 A;  4D5U A;  2XE5 A;  2POR A;  4FT6 A;  2J1N A;  5FVN A;  4AUI A;  3POU A;  3EMN X;  3POX A;  1BT9 A;  1E54 A;  2FGQ X;  2XE3 A;  3A2S X;  1PRN A;  5DL5 A;  3SYB A;  4KRA A;  4FOZ A;  4D65 A;  4FRT A;  2K4T A;  1HXU A;  1GFP A;  2Y0K A;  1OSM A;  7PRN A;  4C69 X;  2Y0L A;  2XG6 A;  4D64 A;  2XE1 A;  5DL7 A;  1HXT A;  4LSE A;  1PHO A;  2PRN A;  3PRN A;  2QTK A; 
#chains in the Genus database with same CATH topology
 3NJT A;  1QJ8 A;  4FES A;  4N59 A;  2X9K A;  4GHB A;  1Q9G A;  5PRN A;  1GFQ A;  2XMX A;  3JTY A;  2XE2 A;  3HWB A;  5G3A A;  2W80 C;  4U9C A;  2Y2X A;  4GCP A;  4N58 A;  3G7G A;  3KZI O;  1MPF A;  3HOL A;  2LFU A;  1S5L O;  1ZHW A;  3A0B O;  3AA7 A;  1T1L A;  3JCU O;  3PF1 A;  3POQ A;  3SZD A;  3TZG A;  4GCQ A;  2Y0H A;  1P4T A;  3C5O A;  3DZM A;  2W81 C;  3UAQ A;  4AYE C;  4JFB A;  4LSH A;  5DL6 A;  4K3B A;  4QQ1 A;  2IWW A;  3SY7 A;  3NSG A;  3T24 A;  1T16 A;  3SZV A;  3PQS A;  4PUX A;  3WI4 A;  2F1C X;  2KZ7 A;  4RJX A;  3VY8 X;  3FYX A;  4O4U A;  2R4P A;  4G75 A;  4B61 A;  3T20 A;  1QJ9 A;  4FMS A;  4LSF A;  4UB6 O;  3T0S A;  3AAE A;  5KAF O;  3VE1 A;  1GFO A;  2XTR A;  2ZLD A;  3VY9 X;  2F1V A;  5EE2 A;  1H6S 1;  3AA7 B;  3UU2 A;  2XTQ A;  2KDY A;  4FSO A;  2JMM A;  4AYN A;  4Z3T A;  4RLC A;  4C4V A;  5E79 O;  4UB8 O;  3VZT X;  5G39 A;  3SY9 A;  2ZFG A;  3HW9 A;  1HXX A;  4O3Z A;  3SYS A;  2JQY A;  5JDP A;  4FZN A;  1ZHX A;  3VZU X;  2R4N A;  2N2L A;  5GV0 A;  1G90 A;  3PQU A;  1GFN A;  4AZL A;  3AA6 A;  1BXW A;  4BUM X;  2OMF A;  3PGS A;  2KZ7 B;  2J4U P;  2MNH A;  2KC0 A;  2WJQ A;  3LK2 A;  5G26 A;  8PRN A;  1MM5 A;  1YS5 A;  4FZL A;  2N2M A;  5KAI O;  3K19 A;  1BH3 A;  3AAE B;  2KXP A;  3UPG A;  2AXT O;  4AFK A;  4AKR A;  3GP6 A;  2FGR A;  2R89 A;  2M07 A;  2ODJ A;  3DWN A;  4O3Y A;  4KR4 A;  4FUV A;  4E1T A;  3O0E A;  3VZW X;  4C00 A;  4CTD A;  2GE4 A;  3QRA A;  3DA4 A;  4FSP A;  4C4V B;  2F1T A;  1OPF A;  2R88 A;  4LSI A;  5IYU A;  3POR A;  3DA3 A;  2O4V A;  4RJW A;  5DL8 A;  3BRY A;  4GCS A;  4FRX A;  1GFM A;  4E1S A;  5ADX L;  5B5E O;  3AA6 B;  4F4B A;  6PRN A;  3A0H O;  2YPV A;  4KR8 A;  3WI5 A;  4AYM C;  4D5U A;  5AFU L;  2XE5 A;  4O49 A;  2MHL A;  4O4X A;  2POR A;  4PR7 A;  2Y7S A;  1IZN A;  1MM4 A;  3LK2 B;  4FT6 A;  2J1N A;  5B66 O;  3AAA B;  5GTI O;  3QRC A;  5FVN A;  2KXP B;  2M06 A;  3BRZ A;  4AUI A;  2YNK A;  2R4O A;  3POU A;  4N74 A;  4AKR B;  4PJ0 O;  3EMN X;  3AAA A;  2R8A A;  3AA0 A;  3LK3 B;  5G38 A;  3KVD D;  3VE2 A;  5H2F O;  3POX A;  1BT9 A;  3AA1 A;  3HOE A;  3LK4 2;  1QJP A;  1E54 A;  2FGQ X;  3BS0 A;  4FZM A;  5T5F A;  3RBH A;  4AYD C;  3LK3 A;  2WVP A;  5AFU K;  2XE3 A;  2X27 X;  3A2S X;  1PRN A;  5DL5 A;  5GTH O;  3SYB A;  4AYI D;  4KRA A;  4FOZ A;  4G76 A;  4RLB A;  1ORM A;  1ZHY A;  4O3W A;  2K0L A;  4K3C A;  5D5D A;  4AKM A;  3PGR A;  2R4L A;  4FRT A;  2K4T A;  1IZN B;  4D65 A;  3LK4 1;  1HXU A;  4IL6 O;  4JCH A;  2IWV A;  2ERV A;  1GFP A;  2Y0K A;  3DWO X;  4FQE A;  4RL9 A;  1OSM A;  3WU2 O;  4XNL A;  4C69 X;  7PRN A;  1ZHZ A;  5TIS O;  2Y0L A;  2XG6 A;  4O3X B;  4XNK A;  4D64 A;  2XE1 A;  3AA0 B;  3V8U A;  1Q9F A;  3PGU A;  5ADX K;  5DL7 A;  1HXT A;  3AA1 B;  4LSE A;  1PHO A;  1ZHT A;  2PRN A;  3PRN A;  4GF4 A;  4N75 A;  2LHF A;  2QTK A;  1THQ A;  2WJR A; 
#chains in the Genus database with same CATH homology
 4FES A;  1QJ8 A;  4N59 A;  4GHB A;  1Q9G A;  5PRN A;  1GFQ A;  2XMX A;  3JTY A;  2XE2 A;  3HWB A;  2W80 C;  4U9C A;  2Y2X A;  4GCP A;  4N58 A;  3G7G A;  1MPF A;  3HOL A;  2LFU A;  1ZHW A;  3AA7 A;  3POQ A;  3SZD A;  3TZG A;  4GCQ A;  2Y0H A;  1P4T A;  3C5O A;  3UAQ A;  2W81 C;  4AYE C;  4JFB A;  4LSH A;  5DL6 A;  4QQ1 A;  3SY7 A;  3NSG A;  3T24 A;  3SZV A;  3PQS A;  4PUX A;  3WI4 A;  3VY8 X;  2KZ7 A;  4RJX A;  3FYX A;  4O4U A;  4G75 A;  4B61 A;  3T20 A;  1QJ9 A;  4FMS A;  4LSF A;  3T0S A;  3AAE A;  3VE1 A;  1GFO A;  2XTR A;  2ZLD A;  3VY9 X;  2F1V A;  5EE2 A;  1H6S 1;  3AA7 B;  3UU2 A;  2XTQ A;  2KDY A;  4FSO A;  2JMM A;  4AYN A;  4Z3T A;  4RLC A;  3VZT X;  3SY9 A;  2ZFG A;  3HW9 A;  1HXX A;  4O3Z A;  3SYS A;  5JDP A;  4FZN A;  1ZHX A;  3VZU X;  1G90 A;  2N2L A;  5GV0 A;  3PQU A;  1GFN A;  4AZL A;  3AA6 A;  1BXW A;  4BUM X;  2OMF A;  2KZ7 B;  2J4U P;  2MNH A;  2KC0 A;  3LK2 A;  5G26 A;  8PRN A;  1MM5 A;  1YS5 A;  4FZL A;  2N2M A;  3K19 A;  1BH3 A;  3AAE B;  2KXP A;  3UPG A;  4AFK A;  4AKR A;  3GP6 A;  2FGR A;  2M07 A;  2ODJ A;  4O3Y A;  4KR4 A;  4FUV A;  4E1T A;  3O0E A;  3VZW X;  2GE4 A;  3QRA A;  3DA4 A;  4FSP A;  5IYU A;  2F1T A;  1OPF A;  4LSI A;  3POR A;  3DA3 A;  2O4V A;  4RJW A;  5DL8 A;  4GCS A;  4FRX A;  1GFM A;  4E1S A;  5ADX L;  6PRN A;  3AA6 B;  4F4B A;  2YPV A;  4KR8 A;  3WI5 A;  4AYM C;  4D5U A;  5AFU L;  2XE5 A;  4O49 A;  2MHL A;  4O4X A;  2POR A;  2Y7S A;  1IZN A;  1MM4 A;  3LK2 B;  4FT6 A;  2J1N A;  3AAA B;  3QRC A;  5FVN A;  2KXP B;  2M06 A;  4AUI A;  2YNK A;  3POU A;  4AKR B;  3EMN X;  3AAA A;  3AA0 A;  3LK3 B;  3VE2 A;  3KVD D;  3POX A;  1BT9 A;  3AA1 A;  3HOE A;  3LK4 2;  1QJP A;  1E54 A;  2FGQ X;  4FZM A;  5T5F A;  3RBH A;  4AYD C;  3LK3 A;  5AFU K;  2XE3 A;  2X27 X;  3A2S X;  1PRN A;  5DL5 A;  3SYB A;  4AYI D;  4KRA A;  4FOZ A;  4G76 A;  4RLB A;  1ORM A;  1ZHY A;  4O3W A;  2K0L A;  5D5D A;  4AKM A;  4D65 A;  4FRT A;  2K4T A;  1IZN B;  3LK4 1;  1HXU A;  4JCH A;  2ERV A;  1GFP A;  2Y0K A;  4RL9 A;  1OSM A;  7PRN A;  4XNL A;  4C69 X;  1ZHZ A;  2Y0L A;  2XG6 A;  4O3X B;  4XNK A;  4D64 A;  2XE1 A;  3AA0 B;  3V8U A;  1Q9F A;  5ADX K;  5DL7 A;  1HXT A;  3AA1 B;  4LSE A;  1PHO A;  1ZHT A;  2PRN A;  3PRN A;  4GF4 A;  2LHF A;  2QTK A;  1THQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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