1A86A

Mmp8 with malonic and aspartic acid based inhibitor
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
158
structure length
158
Chain Sequence
NPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data.
pubmed rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords MMP-8
total genus 46
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.34: Neutrophil collagenase.
pdb deposition date 1998-04-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1a86A00
4WK7A 3LJGA 2RJQA 3HYGA 1GE5A 2JSDA 3CKIA 1JAOA 1GO8P 4GUYA 3LJZA 3KMCA 3F15A 4J4MA 1I73A 4AUOA 1QICA 1CGFA 4WKIA 4HX3A 1UTZA 3EHYA 2QPJA 3K7NA 1HY7A 3EWJA 2OXUA 4ON1A 3L0VA 1KAPP 1GXDA 2DDFA 2JT5A 4JIJA 2WO9A 3P24A 1QJJA 4AIGA 4H82A 1FLSA 4Q1LA 3HDBA 3EDGA 1BQQM 1G49A 1OM8A 3HBUP 1Y8JA 4G9LA 3DPFA 1RM8A 1ZXVA 1XUDA 4PKWA 1HTDA 5D7WA 1XFWA 1IABA 1CGLA 2E3XA 3AYUA 3TS4A 1KUKA 3LJTA 1KUFA 2OXWA 1XURA 1MNCA 1ASTA 3TSKA 1BKCA 4H49A 3ZXHA 3WV3A 1YCMA 1MMBA 2DW0A 966CA 1GKCA 3KECA 4FXYP 3KWVC 2DW2A 2XS4A 3I7GA 2MZEA 4FXQA 1HFSA 2W15A 1R1HA 2OZRA 3ZVSA 2W13A 4GQLA 3USNA 2WO8A 1BQOA 4L19A 4PKRA 3KMEA 3V96B 5JMYA 1G05A 4H76A 3HBVP 3Q2HA 1K7GA 2W0DA 4L6TA 2L0RA 3E8RA 1ZP5A 4GWNA 1YP1A 3RTSA 1QUAA 1KBCA 5D2BA 3N2VA 4GF1A 3F18A 2Z2DA 1IADA 1CK7A 5D3CA 1G4KA 1DMTA 3KEJA 2PJTA 5LABA 1JKYA 2OW1A 2OVXA 1C8TA 1JAPA 1BUVM 1CQRA 4HMAA 2XS3A 1ND1A 4ILWD 1J7NA 5BPAA 1FBLA 2USNA 1RMZA 4JP4A 3U1RA 1D8MA 3F19A 4JPAA 3GBOA 5BOTA 2TCLA 1BSWA 830CA 1BZSA 3B92A 4G0DA 2RJPA 1R1JA 2N8RA 2Y6CA 3HY9A 1OS9A 3KEKA 1ZVXA 4GR8A 3DWBA 5I4OA 1QIAA 2K2GA 1ATLA 1IAAA 1D5JA 2J0TA 1PWWA 2W12A 3Q2GA 2O3EA 1B8YA 1OS2A 1XFZA 3LE9A 1AF0A 1IACA 1BKCE 1USNA 3OHLA 1L6JA 3LQ0A 3F16A 2SRTA 1I76A 1JAQA 4AYKA 1UTTA 2K9CA 1A85A 1IAGA 4FU4A 3BA0A 4PKQA 4QKZA 1MMPA 3KRYA 4A7BA 1MMRA 1XFXA 2I47A 1XUCA 4I03A 5B5OA 4GWMA 2YIGA 1AYKA 1IAEA 1SRPA 2DW1A 1GKDA 3B2ZA 1UEAA 4I35A 1FM1A 1R55A 1OM7A 1ZTQA 3LK8A 4IUWA 3TVCA 3WV1A 2CKIA 3RTTA 1K7IA 2DDYA 4DV8A 4H2EA 1JIWP 3ZUKA 1ROSA 3P1VA 3UVCA 2D1OA 4ZR5A 2OXZA 4PKVA 3HB2P 3LILA 1BUDA 3LEAA 1CIZA 1S4BP 1C7KA 1ZS0A 4FVLA 1YQYA 2JT6A 4DPEA 1SATA 1Y0VA 3AYKA 3LGPA 2MZIA 1HFCA 3EHXA 4PKTA 1CXVA 5CUHA 3TT4A 2ERQA 1OM6A 456CA 2POJA 5I3MA 4IN9A 5CZMA 1OO9A 2MLRA 3KHIA 2X7MA 2OI0A 2O36A 2JIHA 3O2XA 2EROA 4DF9A 1HOVA 2OW0A 4IJOA 3I7IA 2OY2A 3LIRA 2OY4A 1KUIA 3F17A 5D1UA 1PWUA 4WZVA 3SHIA 4WF6A 5D1SA 1R54A 1CGEA 1SMPA 1B3DA 2FV5A 3ELMA 5I0LA 1G9KA 1DTHA 1Y93A 5CXAA 1AKLA 1BIWA 3LQBA 5B5PA 1QIBA 2AYKA 3HDAP 3WV2A 3VTGA 4H3XA 1JH1A 3G5CA 1D7XA 1EUBA 2KRJA 2X3BA 2Y6DA 2JNPA 1UMTA 4H84A 4XM8A 2OVZA 2MZHA 1O0QA 1XFYA 1GE7A 5BOYA 3OHOA 1BKCI 1XFVA 1SU3A 1GO7P 1H71P 2D1NA 5I43A 2FV9A 1C3IA 3DL1A 5H8XA 1R1IA 1G12A 4AXQA 2MLSA 4JA1A 3EDHA 3LKAA 1Z3JA 1GE6A 4WKEA 4XM7A 1JIZA 3VI1A 1JANA 4CTHA 4GR3A 2AIGP 4GR0A 1EAKA 3L0TA 1KUGA 5I12A 1YOUA 1I1IP 1SLNA 2X3CA 3K7LA 1JK3A 2CLTA 5L7FA 2YB9A 1QJIA 4PKUA 3HY7A 2OW2A 1JJ9A 2HU6A 2OW9A 3N2UA 3MA2A 4PKSA 3DSLA 4DD8A 5L79A 1ZXCA 4JQGA 4H1QA 1OMJA 4XM6A 3O64A 4XCTA 1KUHA 1SLMA 1XFUA 4L63A 1PWQA 3NX7A 1UMSA 2ERPA 3DNGA 4H30A 5D1TA 1HV5A 3G42A 3EDIA 1PWPA 3LUNA 2W14A 1O0TA 2E2DA 1Q3AA 1K7QA 1PWVA 3LIKA 2WOAA 4XBHA 1D8FA 1CAQA 1A86A 3DPEA 4A3WA 3AIGA 5I2ZA 2X3AA 1BM6A 3F1AA 2V4BA 1MMQA 3LUMA 1EB6A 2A8HA 3EDZA 3B8ZA 2J83A 3LMCA 4EFSA 4R3VA 1WNIA
chains in the Genus database with same CATH superfamily
4WK7A 3LJGA 2RJQA 3HYGA 1GE5A 1TVIA 2JSDA 3CKIA 1JAOA 1GO8P 4GUYA 3LJZA 3KMCA 3F15A 4J4MA 1I73A 4AUOA 1QICA 1CGFA 4WKIA 4HX3A 1UTZA 3EHYA 2QPJA 3K7NA 1HY7A 3EWJA 2OXUA 4ON1A 3L0VA 1KAPP 1GXDA 2DDFA 2JT5A 4JIJA 2WO9A 3P24A 1QJJA 4AIGA 4H82A 1FLSA 4Q1LA 3HDBA 3EDGA 1BQQM 1G49A 1OM8A 3HBUP 1Y8JA 4G9LA 3DPFA 1RM8A 1ZXVA 1XUDA 4PKWA 1HTDA 5D7WA 1XFWA 1IABA 1CGLA 2E3XA 3AYUA 3TS4A 1KUKA 3LJTA 1KUFA 3DTEA 2OXWA 1XURA 1MNCA 1ASTA 3TSKA 1BKCA 4H49A 3ZXHA 3DTKA 3WV3A 1YCMA 1MMBA 2DW0A 966CA 1GKCA 3KECA 4FXYP 3KWVC 2DW2A 2XS4A 3I7GA 2MZEA 4FXQA 1HFSA 2W15A 1R1HA 2OZRA 3ZVSA 2W13A 4GQLA 3USNA 2WO8A 1BQOA 4L19A 4PKRA 3KMEA 3V96B 5JMYA 1G05A 4H76A 3HBVP 3Q2HA 1K7GA 2W0DA 4L6TA 2L0RA 3E8RA 1ZP5A 4GWNA 1YP1A 3RTSA 1QUAA 1KBCA 2YUFA 5D2BA 3N2VA 4GF1A 3F18A 2Z2DA 1IADA 1CK7A 5D3CA 1G4KA 1DMTA 3KEJA 4L7AA 2PJTA 5LABA 1JKYA 2OW1A 2OVXA 1C8TA 1JAPA 1BUVM 1CQRA 4HMAA 2XS3A 1ND1A 4ILWD 1J7NA 5BPAA 1FBLA 2USNA 1RMZA 4JP4A 3U1RA 1D8MA 3F19A 4JPAA 3GBOA 5BOTA 2TCLA 1BSWA 830CA 1BZSA 3B92A 4G0DA 2RJPA 1R1JA 2N8RA 2Y6CA 3HY9A 1OS9A 3KEKA 1ZVXA 4GR8A 3DWBA 5I4OA 1QIAA 2K2GA 1ATLA 1IAAA 1D5JA 2J0TA 1PWWA 2W12A 3Q2GA 2O3EA 1B8YA 1OS2A 1XFZA 3LE9A 1AF0A 1IACA 1BKCE 1USNA 3OHLA 1L6JA 3LQ0A 3F16A 2SRTA 1I76A 1JAQA 4AYKA 1UTTA 2K9CA 1A85A 1IAGA 4FU4A 3BA0A 4PKQA 4QKZA 1MMPA 3KRYA 4A7BA 1MMRA 1XFXA 2I47A 1XUCA 4I03A 5B5OA 4GWMA 2YIGA 1AYKA 1IAEA 1SRPA 2DW1A 1GKDA 3B2ZA 1UEAA 1XM5A 4I35A 1FM1A 1R55A 1OM7A 1ZTQA 3LK8A 4IUWA 3TVCA 3WV1A 2CKIA 3RTTA 1K7IA 2DDYA 4DV8A 4H2EA 1JIWP 3ZUKA 1ROSA 3P1VA 3UVCA 2D1OA 4ZR5A 2OXZA 4PKVA 3HB2P 3LILA 1BUDA 3LEAA 1CIZA 1S4BP 1C7KA 1ZS0A 4FVLA 1YQYA 2JT6A 4DPEA 1SATA 1Y0VA 3AYKA 3LGPA 2MZIA 1HFCA 3EHXA 4PKTA 1CXVA 5CUHA 3TT4A 2ERQA 1OM6A 456CA 2POJA 5I3MA 4IN9A 5CZMA 1OO9A 2MLRA 3KHIA 2X7MA 2OI0A 2O36A 2JIHA 3O2XA 2EROA 4DF9A 1HOVA 2OW0A 4IJOA 3I7IA 2OY2A 3LIRA 2OY4A 1KUIA 3F17A 5D1UA 1PWUA 4WZVA 3SHIA 4WF6A 5D1SA 1R54A 1CGEA 1SMPA 1B3DA 2FV5A 3ELMA 5I0LA 1G9KA 1DTHA 1Y93A 5CXAA 1AKLA 1BIWA 3LQBA 5B5PA 1QIBA 2AYKA 3HDAP 3WV2A 3VTGA 4H3XA 1JH1A 3G5CA 1D7XA 1EUBA 2KRJA 2X3BA 2Y6DA 2JNPA 1UMTA 4H84A 4XM8A 2OVZA 2MZHA 1O0QA 1XFYA 1GE7A 5BOYA 3OHOA 1BKCI 1XFVA 3DTIA 1SU3A 1GO7P 1H71P 2D1NA 5I43A 2FV9A 1C3IA 3DL1A 5H8XA 1R1IA 1G12A 4AXQA 2MLSA 4JA1A 3EDHA 3LKAA 1Z3JA 1GE6A 4WKEA 4XM7A 1JIZA 3VI1A 1JANA 4CTHA 4GR3A 2AIGP 4GR0A 1EAKA 3L0TA 1KUGA 5I12A 1YOUA 1I1IP 1SLNA 2X3CA 3K7LA 1JK3A 2CLTA 5L7FA 2YB9A 1QJIA 4PKUA 3HY7A 2OW2A 1JJ9A 2HU6A 2OW9A 3N2UA 3MA2A 4PKSA 3DSLA 4DD8A 5L79A 1ZXCA 4JQGA 4H1QA 1OMJA 1OZ9A 4XM6A 3O64A 4XCTA 1KUHA 1SLMA 1XFUA 4L63A 1PWQA 3NX7A 1UMSA 2ERPA 3DNGA 4H30A 5D1TA 1HV5A 3G42A 3EDIA 1PWPA 3LUNA 2W14A 1O0TA 2E2DA 1Q3AA 1K7QA 1PWVA 3LIKA 2WOAA 4XBHA 1D8FA 1CAQA 1A86A 1XAXA 3DPEA 4A3WA 3AIGA 5I2ZA 2X3AA 1BM6A 3F1AA 2V4BA 1MMQA 3LUMA 1EB6A 2A8HA 3EDZA 3B8ZA 2J83A 3LMCA 4EFSA 4R3VA 1WNIA
chains in the Genus database with same CATH topology
4WK7A 3LJGA 2RJQA 3HYGA 1GE5A 2JSDA 3CKIA 1JAOA 1GO8P 4GUYA 3LJZA 3KMCA 3F15A 4J4MA 1I73A 4AUOA 1QICA 1CGFA 4WKIA 4HX3A 1UTZA 3EHYA 2QPJA 3K7NA 1HY7A 3EWJA 2OXUA 4ON1A 3L0VA 1KAPP 1GXDA 2DDFA 2JT5A 4JIJA 2WO9A 3P24A 1QJJA 4AIGA 4H82A 1FLSA 4Q1LA 3HDBA 3EDGA 1BQQM 1G49A 1OM8A 3HBUP 1Y8JA 4G9LA 3DPFA 1RM8A 1ZXVA 1XUDA 4PKWA 1HTDA 5D7WA 1XFWA 1IABA 1CGLA 2E3XA 3AYUA 3TS4A 1KUKA 3LJTA 1KUFA 3DTEA 2OXWA 1XURA 1MNCA 1ASTA 3TSKA 1BKCA 4H49A 3ZXHA 3DTKA 3WV3A 1YCMA 1MMBA 2DW0A 966CA 1GKCA 3KECA 4FXYP 3KWVC 2DW2A 2XS4A 3I7GA 2MZEA 4FXQA 1HFSA 2W15A 1R1HA 2OZRA 3ZVSA 2W13A 4GQLA 3USNA 2WO8A 1BQOA 4L19A 4PKRA 3KMEA 3V96B 5JMYA 1G05A 4H76A 3HBVP 3Q2HA 1K7GA 2W0DA 4L6TA 2L0RA 3E8RA 1ZP5A 4GWNA 1YP1A 3RTSA 1QUAA 1KBCA 2YUFA 5D2BA 3N2VA 4GF1A 3F18A 2Z2DA 1IADA 1CK7A 5D3CA 1G4KA 1DMTA 3KEJA 4L7AA 2PJTA 5LABA 1JKYA 2OW1A 2OVXA 1C8TA 1JAPA 1BUVM 1CQRA 4HMAA 2XS3A 1ND1A 4ILWD 1J7NA 5BPAA 1FBLA 2USNA 1RMZA 4JP4A 3U1RA 1D8MA 3F19A 4JPAA 3GBOA 5BOTA 2TCLA 1BSWA 830CA 1BZSA 3B92A 4G0DA 2RJPA 1R1JA 2N8RA 2Y6CA 3HY9A 1OS9A 3KEKA 1ZVXA 4GR8A 3DWBA 5I4OA 1QIAA 2K2GA 1ATLA 1IAAA 1D5JA 2J0TA 1PWWA 2W12A 3Q2GA 2O3EA 1B8YA 1OS2A 1XFZA 3LE9A 1AF0A 1IACA 1BKCE 1USNA 3OHLA 1L6JA 3LQ0A 3F16A 2SRTA 1I76A 1JAQA 4AYKA 1UTTA 2K9CA 1A85A 1IAGA 4FU4A 3BA0A 4PKQA 4QKZA 1MMPA 3KRYA 4A7BA 1MMRA 1XFXA 2I47A 1XUCA 4I03A 5B5OA 4GWMA 2YIGA 1AYKA 1IAEA 1SRPA 2DW1A 1GKDA 3B2ZA 1UEAA 4I35A 1FM1A 1R55A 1OM7A 1ZTQA 3LK8A 4IUWA 3TVCA 3WV1A 2CKIA 3RTTA 1K7IA 2DDYA 4DV8A 4H2EA 1JIWP 3ZUKA 1ROSA 3P1VA 3UVCA 2D1OA 4ZR5A 2OXZA 4PKVA 3HB2P 3LILA 1BUDA 3LEAA 1CIZA 1S4BP 1C7KA 1ZS0A 4FVLA 1YQYA 2JT6A 4DPEA 1SATA 1Y0VA 3AYKA 3LGPA 2MZIA 1HFCA 3EHXA 4PKTA 1CXVA 5CUHA 3TT4A 2ERQA 1OM6A 456CA 2POJA 5I3MA 4IN9A 5CZMA 1OO9A 2MLRA 3KHIA 2X7MA 2OI0A 2O36A 2JIHA 3O2XA 2EROA 4DF9A 1HOVA 2OW0A 4IJOA 3I7IA 2OY2A 3LIRA 2OY4A 1KUIA 3F17A 5D1UA 1PWUA 4WZVA 3SHIA 4WF6A 5D1SA 1R54A 1CGEA 1SMPA 1B3DA 2FV5A 3ELMA 5I0LA 1G9KA 1DTHA 1Y93A 5CXAA 1AKLA 1BIWA 3LQBA 5B5PA 1QIBA 2AYKA 3HDAP 3WV2A 3VTGA 4H3XA 1JH1A 3G5CA 1D7XA 1EUBA 2KRJA 2X3BA 2Y6DA 2JNPA 1UMTA 4H84A 4XM8A 2OVZA 2MZHA 1O0QA 1XFYA 1GE7A 5BOYA 3OHOA 1BKCI 1XFVA 3DTIA 1SU3A 1GO7P 1H71P 2D1NA 5I43A 2FV9A 1C3IA 3DL1A 5H8XA 1R1IA 1G12A 4AXQA 2MLSA 4JA1A 3EDHA 3LKAA 1Z3JA 1GE6A 4WKEA 4XM7A 1JIZA 3VI1A 1JANA 4CTHA 4GR3A 2AIGP 4GR0A 1EAKA 3L0TA 1KUGA 5I12A 1YOUA 1I1IP 1SLNA 2X3CA 3K7LA 1JK3A 2CLTA 5L7FA 2YB9A 1QJIA 4PKUA 3HY7A 2OW2A 1JJ9A 2HU6A 2OW9A 3N2UA 3MA2A 4PKSA 3DSLA 4DD8A 5L79A 1ZXCA 4JQGA 4H1QA 1OMJA 4XM6A 3O64A 4XCTA 1KUHA 1SLMA 1XFUA 4L63A 1PWQA 3NX7A 1UMSA 2ERPA 3DNGA 4H30A 5D1TA 1HV5A 3G42A 3EDIA 1PWPA 3LUNA 2W14A 1O0TA 2E2DA 1Q3AA 1K7QA 1PWVA 3LIKA 2WOAA 4XBHA 1D8FA 1CAQA 1A86A 3DPEA 4A3WA 3AIGA 5I2ZA 2X3AA 1BM6A 3F1AA 2V4BA 1MMQA 3LUMA 1EB6A 2A8HA 3EDZA 3B8ZA 2J83A 3LMCA 4EFSA 4R3VA 1WNIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WK7 A;  3LJG A;  2RJQ A;  3HYG A;  1GE5 A;  2JSD A;  3CKI A;  1JAO A;  1GO8 P;  4GUY A;  3LJZ A;  3KMC A;  3F15 A;  4J4M A;  1I73 A;  4AUO A;  1QIC A;  1CGF A;  4WKI A;  4HX3 A;  1UTZ A;  3EHY A;  2QPJ A;  3K7N A;  1HY7 A;  3EWJ A;  2OXU A;  4ON1 A;  3L0V A;  1KAP P;  1GXD A;  2DDF A;  2JT5 A;  4JIJ A;  2WO9 A;  3P24 A;  1QJJ A;  4AIG A;  4H82 A;  1FLS A;  4Q1L A;  3HDB A;  3EDG A;  1BQQ M;  1G49 A;  1OM8 A;  3HBU P;  1Y8J A;  4G9L A;  3DPF A;  1RM8 A;  1ZXV A;  1XUD A;  4PKW A;  1HTD A;  5D7W A;  1XFW A;  1IAB A;  1CGL A;  2E3X A;  3AYU A;  3TS4 A;  1KUK A;  3LJT A;  1KUF A;  2OXW A;  1XUR A;  1MNC A;  1AST A;  3TSK A;  1BKC A;  4H49 A;  3ZXH A;  3WV3 A;  1YCM A;  1MMB A;  2DW0 A;  966C A;  1GKC A;  3KEC A;  4FXY P;  3KWV C;  2DW2 A;  2XS4 A;  3I7G A;  2MZE A;  4FXQ A;  1HFS A;  2W15 A;  1R1H A;  2OZR A;  3ZVS A;  2W13 A;  4GQL A;  3USN A;  2WO8 A;  1BQO A;  4L19 A;  4PKR A;  3KME A;  3V96 B;  5JMY A;  1G05 A;  4H76 A;  3HBV P;  3Q2H A;  1K7G A;  2W0D A;  4L6T A;  2L0R A;  3E8R A;  1ZP5 A;  4GWN A;  1YP1 A;  3RTS A;  1QUA A;  1KBC A;  5D2B A;  3N2V A;  4GF1 A;  3F18 A;  2Z2D A;  1IAD A;  1CK7 A;  5D3C A;  1G4K A;  1DMT A;  3KEJ A;  2PJT A;  5LAB A;  1JKY A;  2OW1 A;  2OVX A;  1C8T A;  1JAP A;  1BUV M;  1CQR A;  4HMA A;  2XS3 A;  1ND1 A;  4ILW D;  1J7N A;  5BPA A;  1FBL A;  2USN A;  1RMZ A;  4JP4 A;  3U1R A;  1D8M A;  3F19 A;  4JPA A;  3GBO A;  5BOT A;  2TCL A;  1BSW A;  830C A;  1BZS A;  3B92 A;  4G0D A;  2RJP A;  1R1J A;  2N8R A;  2Y6C A;  3HY9 A;  1OS9 A;  3KEK A;  1ZVX A;  4GR8 A;  3DWB A;  5I4O A;  1QIA A;  2K2G A;  1ATL A;  1IAA A;  1D5J A;  2J0T A;  1PWW A;  2W12 A;  3Q2G A;  2O3E A;  1B8Y A;  1OS2 A;  1XFZ A;  3LE9 A;  1AF0 A;  1IAC A;  1BKC E;  1USN A;  3OHL A;  1L6J A;  3LQ0 A;  3F16 A;  2SRT A;  1I76 A;  1JAQ A;  4AYK A;  1UTT A;  2K9C A;  1A85 A;  1IAG A;  4FU4 A;  3BA0 A;  4PKQ A;  4QKZ A;  1MMP A;  3KRY A;  4A7B A;  1MMR A;  1XFX A;  2I47 A;  1XUC A;  4I03 A;  5B5O A;  4GWM A;  2YIG A;  1AYK A;  1IAE A;  1SRP A;  2DW1 A;  1GKD A;  3B2Z A;  1UEA A;  4I35 A;  1FM1 A;  1R55 A;  1OM7 A;  1ZTQ A;  3LK8 A;  4IUW A;  3TVC A;  3WV1 A;  2CKI A;  3RTT A;  1K7I A;  2DDY A;  4DV8 A;  4H2E A;  1JIW P;  3ZUK A;  1ROS A;  3P1V A;  3UVC A;  2D1O A;  4ZR5 A;  2OXZ A;  4PKV A;  3HB2 P;  3LIL A;  1BUD A;  3LEA A;  1CIZ A;  1S4B P;  1C7K A;  1ZS0 A;  4FVL A;  1YQY A;  2JT6 A;  4DPE A;  1SAT A;  1Y0V A;  3AYK A;  3LGP A;  2MZI A;  1HFC A;  3EHX A;  4PKT A;  1CXV A;  5CUH A;  3TT4 A;  2ERQ A;  1OM6 A;  456C A;  2POJ A;  5I3M A;  4IN9 A;  5CZM A;  1OO9 A;  2MLR A;  3KHI A;  2X7M A;  2OI0 A;  2O36 A;  2JIH A;  3O2X A;  2ERO A;  4DF9 A;  1HOV A;  2OW0 A;  4IJO A;  3I7I A;  2OY2 A;  3LIR A;  2OY4 A;  1KUI A;  3F17 A;  5D1U A;  1PWU A;  4WZV A;  3SHI A;  4WF6 A;  5D1S A;  1R54 A;  1CGE A;  1SMP A;  1B3D A;  2FV5 A;  3ELM A;  5I0L A;  1G9K A;  1DTH A;  1Y93 A;  5CXA A;  1AKL A;  1BIW A;  3LQB A;  5B5P A;  1QIB A;  2AYK A;  3HDA P;  3WV2 A;  3VTG A;  4H3X A;  1JH1 A;  3G5C A;  1D7X A;  1EUB A;  2KRJ A;  2X3B A;  2Y6D A;  2JNP A;  1UMT A;  4H84 A;  4XM8 A;  2OVZ A;  2MZH A;  1O0Q A;  1XFY A;  1GE7 A;  5BOY A;  3OHO A;  1BKC I;  1XFV A;  1SU3 A;  1GO7 P;  1H71 P;  2D1N A;  5I43 A;  2FV9 A;  1C3I A;  3DL1 A;  5H8X A;  1R1I A;  1G12 A;  4AXQ A;  2MLS A;  4JA1 A;  3EDH A;  3LKA A;  1Z3J A;  1GE6 A;  4WKE A;  4XM7 A;  1JIZ A;  3VI1 A;  1JAN A;  4CTH A;  4GR3 A;  2AIG P;  4GR0 A;  1EAK A;  3L0T A;  1KUG A;  5I12 A;  1YOU A;  1I1I P;  1SLN A;  2X3C A;  3K7L A;  1JK3 A;  2CLT A;  5L7F A;  2YB9 A;  1QJI A;  4PKU A;  3HY7 A;  2OW2 A;  1JJ9 A;  2HU6 A;  2OW9 A;  3N2U A;  3MA2 A;  4PKS A;  3DSL A;  4DD8 A;  5L79 A;  1ZXC A;  4JQG A;  4H1Q A;  1OMJ A;  4XM6 A;  3O64 A;  4XCT A;  1KUH A;  1SLM A;  1XFU A;  4L63 A;  1PWQ A;  3NX7 A;  1UMS A;  2ERP A;  3DNG A;  4H30 A;  5D1T A;  1HV5 A;  3G42 A;  3EDI A;  1PWP A;  3LUN A;  2W14 A;  1O0T A;  2E2D A;  1Q3A A;  1K7Q A;  1PWV A;  3LIK A;  2WOA A;  4XBH A;  1D8F A;  1CAQ A;  1A86 A;  3DPE A;  4A3W A;  3AIG A;  5I2Z A;  2X3A A;  1BM6 A;  3F1A A;  2V4B A;  1MMQ A;  3LUM A;  1EB6 A;  2A8H A;  3EDZ A;  3B8Z A;  2J83 A;  3LMC A;  4EFS A;  4R3V A;  1WNI A; 
#chains in the Genus database with same CATH topology
 4WK7 A;  3LJG A;  2RJQ A;  3HYG A;  1GE5 A;  1TVI A;  2JSD A;  3CKI A;  1JAO A;  1GO8 P;  4GUY A;  3LJZ A;  3KMC A;  3F15 A;  4J4M A;  1I73 A;  4AUO A;  1QIC A;  1CGF A;  4WKI A;  4HX3 A;  1UTZ A;  3EHY A;  2QPJ A;  3K7N A;  1HY7 A;  3EWJ A;  2OXU A;  4ON1 A;  3L0V A;  1KAP P;  1GXD A;  2DDF A;  2JT5 A;  4JIJ A;  2WO9 A;  3P24 A;  1QJJ A;  4AIG A;  4H82 A;  1FLS A;  4Q1L A;  3HDB A;  3EDG A;  1BQQ M;  1G49 A;  1OM8 A;  3HBU P;  1Y8J A;  4G9L A;  3DPF A;  1RM8 A;  1ZXV A;  1XUD A;  4PKW A;  1HTD A;  5D7W A;  1XFW A;  1IAB A;  1CGL A;  2E3X A;  3AYU A;  3TS4 A;  1KUK A;  3LJT A;  1KUF A;  3DTE A;  2OXW A;  1XUR A;  1MNC A;  1AST A;  3TSK A;  1BKC A;  4H49 A;  3ZXH A;  3DTK A;  3WV3 A;  1YCM A;  1MMB A;  2DW0 A;  966C A;  1GKC A;  3KEC A;  4FXY P;  3KWV C;  2DW2 A;  2XS4 A;  3I7G A;  2MZE A;  4FXQ A;  1HFS A;  2W15 A;  1R1H A;  2OZR A;  3ZVS A;  2W13 A;  4GQL A;  3USN A;  2WO8 A;  1BQO A;  4L19 A;  4PKR A;  3KME A;  3V96 B;  5JMY A;  1G05 A;  4H76 A;  3HBV P;  3Q2H A;  1K7G A;  2W0D A;  4L6T A;  2L0R A;  3E8R A;  1ZP5 A;  4GWN A;  1YP1 A;  3RTS A;  1QUA A;  1KBC A;  2YUF A;  5D2B A;  3N2V A;  4GF1 A;  3F18 A;  2Z2D A;  1IAD A;  1CK7 A;  5D3C A;  1G4K A;  1DMT A;  3KEJ A;  4L7A A;  2PJT A;  5LAB A;  1JKY A;  2OW1 A;  2OVX A;  1C8T A;  1JAP A;  1BUV M;  1CQR A;  4HMA A;  2XS3 A;  1ND1 A;  4ILW D;  1J7N A;  5BPA A;  1FBL A;  2USN A;  1RMZ A;  4JP4 A;  3U1R A;  1D8M A;  3F19 A;  4JPA A;  3GBO A;  5BOT A;  2TCL A;  1BSW A;  830C A;  1BZS A;  3B92 A;  4G0D A;  2RJP A;  1R1J A;  2N8R A;  2Y6C A;  3HY9 A;  1OS9 A;  3KEK A;  1ZVX A;  4GR8 A;  3DWB A;  5I4O A;  1QIA A;  2K2G A;  1ATL A;  1IAA A;  1D5J A;  2J0T A;  1PWW A;  2W12 A;  3Q2G A;  2O3E A;  1B8Y A;  1OS2 A;  1XFZ A;  3LE9 A;  1AF0 A;  1IAC A;  1BKC E;  1USN A;  3OHL A;  1L6J A;  3LQ0 A;  3F16 A;  2SRT A;  1I76 A;  1JAQ A;  4AYK A;  1UTT A;  2K9C A;  1A85 A;  1IAG A;  4FU4 A;  3BA0 A;  4PKQ A;  4QKZ A;  1MMP A;  3KRY A;  4A7B A;  1MMR A;  1XFX A;  2I47 A;  1XUC A;  4I03 A;  5B5O A;  4GWM A;  2YIG A;  1AYK A;  1IAE A;  1SRP A;  2DW1 A;  1GKD A;  3B2Z A;  1UEA A;  1XM5 A;  4I35 A;  1FM1 A;  1R55 A;  1OM7 A;  1ZTQ A;  3LK8 A;  4IUW A;  3TVC A;  3WV1 A;  2CKI A;  3RTT A;  1K7I A;  2DDY A;  4DV8 A;  4H2E A;  1JIW P;  3ZUK A;  1ROS A;  3P1V A;  3UVC A;  2D1O A;  4ZR5 A;  2OXZ A;  4PKV A;  3HB2 P;  3LIL A;  1BUD A;  3LEA A;  1CIZ A;  1S4B P;  1C7K A;  1ZS0 A;  4FVL A;  1YQY A;  2JT6 A;  4DPE A;  1SAT A;  1Y0V A;  3AYK A;  3LGP A;  2MZI A;  1HFC A;  3EHX A;  4PKT A;  1CXV A;  5CUH A;  3TT4 A;  2ERQ A;  1OM6 A;  456C A;  2POJ A;  5I3M A;  4IN9 A;  5CZM A;  1OO9 A;  2MLR A;  3KHI A;  2X7M A;  2OI0 A;  2O36 A;  2JIH A;  3O2X A;  2ERO A;  4DF9 A;  1HOV A;  2OW0 A;  4IJO A;  3I7I A;  2OY2 A;  3LIR A;  2OY4 A;  1KUI A;  3F17 A;  5D1U A;  1PWU A;  4WZV A;  3SHI A;  4WF6 A;  5D1S A;  1R54 A;  1CGE A;  1SMP A;  1B3D A;  2FV5 A;  3ELM A;  5I0L A;  1G9K A;  1DTH A;  1Y93 A;  5CXA A;  1AKL A;  1BIW A;  3LQB A;  5B5P A;  1QIB A;  2AYK A;  3HDA P;  3WV2 A;  3VTG A;  4H3X A;  1JH1 A;  3G5C A;  1D7X A;  1EUB A;  2KRJ A;  2X3B A;  2Y6D A;  2JNP A;  1UMT A;  4H84 A;  4XM8 A;  2OVZ A;  2MZH A;  1O0Q A;  1XFY A;  1GE7 A;  5BOY A;  3OHO A;  1BKC I;  1XFV A;  3DTI A;  1SU3 A;  1GO7 P;  1H71 P;  2D1N A;  5I43 A;  2FV9 A;  1C3I A;  3DL1 A;  5H8X A;  1R1I A;  1G12 A;  4AXQ A;  2MLS A;  4JA1 A;  3EDH A;  3LKA A;  1Z3J A;  1GE6 A;  4WKE A;  4XM7 A;  1JIZ A;  3VI1 A;  1JAN A;  4CTH A;  4GR3 A;  2AIG P;  4GR0 A;  1EAK A;  3L0T A;  1KUG A;  5I12 A;  1YOU A;  1I1I P;  1SLN A;  2X3C A;  3K7L A;  1JK3 A;  2CLT A;  5L7F A;  2YB9 A;  1QJI A;  4PKU A;  3HY7 A;  2OW2 A;  1JJ9 A;  2HU6 A;  2OW9 A;  3N2U A;  3MA2 A;  4PKS A;  3DSL A;  4DD8 A;  5L79 A;  1ZXC A;  4JQG A;  4H1Q A;  1OMJ A;  1OZ9 A;  4XM6 A;  3O64 A;  4XCT A;  1KUH A;  1SLM A;  1XFU A;  4L63 A;  1PWQ A;  3NX7 A;  1UMS A;  2ERP A;  3DNG A;  4H30 A;  5D1T A;  1HV5 A;  3G42 A;  3EDI A;  1PWP A;  3LUN A;  2W14 A;  1O0T A;  2E2D A;  1Q3A A;  1K7Q A;  1PWV A;  3LIK A;  2WOA A;  4XBH A;  1D8F A;  1CAQ A;  1A86 A;  1XAX A;  3DPE A;  4A3W A;  3AIG A;  5I2Z A;  2X3A A;  1BM6 A;  3F1A A;  2V4B A;  1MMQ A;  3LUM A;  1EB6 A;  2A8H A;  3EDZ A;  3B8Z A;  2J83 A;  3LMC A;  4EFS A;  4R3V A;  1WNI A; 
#chains in the Genus database with same CATH homology
 4WK7 A;  3LJG A;  2RJQ A;  3HYG A;  1GE5 A;  2JSD A;  3CKI A;  1JAO A;  1GO8 P;  4GUY A;  3LJZ A;  3KMC A;  3F15 A;  4J4M A;  1I73 A;  4AUO A;  1QIC A;  1CGF A;  4WKI A;  4HX3 A;  1UTZ A;  3EHY A;  2QPJ A;  3K7N A;  1HY7 A;  3EWJ A;  2OXU A;  4ON1 A;  3L0V A;  1KAP P;  1GXD A;  2DDF A;  2JT5 A;  4JIJ A;  2WO9 A;  3P24 A;  1QJJ A;  4AIG A;  4H82 A;  1FLS A;  4Q1L A;  3HDB A;  3EDG A;  1BQQ M;  1G49 A;  1OM8 A;  3HBU P;  1Y8J A;  4G9L A;  3DPF A;  1RM8 A;  1ZXV A;  1XUD A;  4PKW A;  1HTD A;  5D7W A;  1XFW A;  1IAB A;  1CGL A;  2E3X A;  3AYU A;  3TS4 A;  1KUK A;  3LJT A;  1KUF A;  3DTE A;  2OXW A;  1XUR A;  1MNC A;  1AST A;  3TSK A;  1BKC A;  4H49 A;  3ZXH A;  3DTK A;  3WV3 A;  1YCM A;  1MMB A;  2DW0 A;  966C A;  1GKC A;  3KEC A;  4FXY P;  3KWV C;  2DW2 A;  2XS4 A;  3I7G A;  2MZE A;  4FXQ A;  1HFS A;  2W15 A;  1R1H A;  2OZR A;  3ZVS A;  2W13 A;  4GQL A;  3USN A;  2WO8 A;  1BQO A;  4L19 A;  4PKR A;  3KME A;  3V96 B;  5JMY A;  1G05 A;  4H76 A;  3HBV P;  3Q2H A;  1K7G A;  2W0D A;  4L6T A;  2L0R A;  3E8R A;  1ZP5 A;  4GWN A;  1YP1 A;  3RTS A;  1QUA A;  1KBC A;  2YUF A;  5D2B A;  3N2V A;  4GF1 A;  3F18 A;  2Z2D A;  1IAD A;  1CK7 A;  5D3C A;  1G4K A;  1DMT A;  3KEJ A;  4L7A A;  2PJT A;  5LAB A;  1JKY A;  2OW1 A;  2OVX A;  1C8T A;  1JAP A;  1BUV M;  1CQR A;  4HMA A;  2XS3 A;  1ND1 A;  4ILW D;  1J7N A;  5BPA A;  1FBL A;  2USN A;  1RMZ A;  4JP4 A;  3U1R A;  1D8M A;  3F19 A;  4JPA A;  3GBO A;  5BOT A;  2TCL A;  1BSW A;  830C A;  1BZS A;  3B92 A;  4G0D A;  2RJP A;  1R1J A;  2N8R A;  2Y6C A;  3HY9 A;  1OS9 A;  3KEK A;  1ZVX A;  4GR8 A;  3DWB A;  5I4O A;  1QIA A;  2K2G A;  1ATL A;  1IAA A;  1D5J A;  2J0T A;  1PWW A;  2W12 A;  3Q2G A;  2O3E A;  1B8Y A;  1OS2 A;  1XFZ A;  3LE9 A;  1AF0 A;  1IAC A;  1BKC E;  1USN A;  3OHL A;  1L6J A;  3LQ0 A;  3F16 A;  2SRT A;  1I76 A;  1JAQ A;  4AYK A;  1UTT A;  2K9C A;  1A85 A;  1IAG A;  4FU4 A;  3BA0 A;  4PKQ A;  4QKZ A;  1MMP A;  3KRY A;  4A7B A;  1MMR A;  1XFX A;  2I47 A;  1XUC A;  4I03 A;  5B5O A;  4GWM A;  2YIG A;  1AYK A;  1IAE A;  1SRP A;  2DW1 A;  1GKD A;  3B2Z A;  1UEA A;  4I35 A;  1FM1 A;  1R55 A;  1OM7 A;  1ZTQ A;  3LK8 A;  4IUW A;  3TVC A;  3WV1 A;  2CKI A;  3RTT A;  1K7I A;  2DDY A;  4DV8 A;  4H2E A;  1JIW P;  3ZUK A;  1ROS A;  3P1V A;  3UVC A;  2D1O A;  4ZR5 A;  2OXZ A;  4PKV A;  3HB2 P;  3LIL A;  1BUD A;  3LEA A;  1CIZ A;  1S4B P;  1C7K A;  1ZS0 A;  4FVL A;  1YQY A;  2JT6 A;  4DPE A;  1SAT A;  1Y0V A;  3AYK A;  3LGP A;  2MZI A;  1HFC A;  3EHX A;  4PKT A;  1CXV A;  5CUH A;  3TT4 A;  2ERQ A;  1OM6 A;  456C A;  2POJ A;  5I3M A;  4IN9 A;  5CZM A;  1OO9 A;  2MLR A;  3KHI A;  2X7M A;  2OI0 A;  2O36 A;  2JIH A;  3O2X A;  2ERO A;  4DF9 A;  1HOV A;  2OW0 A;  4IJO A;  3I7I A;  2OY2 A;  3LIR A;  2OY4 A;  1KUI A;  3F17 A;  5D1U A;  1PWU A;  4WZV A;  3SHI A;  4WF6 A;  5D1S A;  1R54 A;  1CGE A;  1SMP A;  1B3D A;  2FV5 A;  3ELM A;  5I0L A;  1G9K A;  1DTH A;  1Y93 A;  5CXA A;  1AKL A;  1BIW A;  3LQB A;  5B5P A;  1QIB A;  2AYK A;  3HDA P;  3WV2 A;  3VTG A;  4H3X A;  1JH1 A;  3G5C A;  1D7X A;  1EUB A;  2KRJ A;  2X3B A;  2Y6D A;  2JNP A;  1UMT A;  4H84 A;  4XM8 A;  2OVZ A;  2MZH A;  1O0Q A;  1XFY A;  1GE7 A;  5BOY A;  3OHO A;  1BKC I;  1XFV A;  3DTI A;  1SU3 A;  1GO7 P;  1H71 P;  2D1N A;  5I43 A;  2FV9 A;  1C3I A;  3DL1 A;  5H8X A;  1R1I A;  1G12 A;  4AXQ A;  2MLS A;  4JA1 A;  3EDH A;  3LKA A;  1Z3J A;  1GE6 A;  4WKE A;  4XM7 A;  1JIZ A;  3VI1 A;  1JAN A;  4CTH A;  4GR3 A;  2AIG P;  4GR0 A;  1EAK A;  3L0T A;  1KUG A;  5I12 A;  1YOU A;  1I1I P;  1SLN A;  2X3C A;  3K7L A;  1JK3 A;  2CLT A;  5L7F A;  2YB9 A;  1QJI A;  4PKU A;  3HY7 A;  2OW2 A;  1JJ9 A;  2HU6 A;  2OW9 A;  3N2U A;  3MA2 A;  4PKS A;  3DSL A;  4DD8 A;  5L79 A;  1ZXC A;  4JQG A;  4H1Q A;  1OMJ A;  4XM6 A;  3O64 A;  4XCT A;  1KUH A;  1SLM A;  1XFU A;  4L63 A;  1PWQ A;  3NX7 A;  1UMS A;  2ERP A;  3DNG A;  4H30 A;  5D1T A;  1HV5 A;  3G42 A;  3EDI A;  1PWP A;  3LUN A;  2W14 A;  1O0T A;  2E2D A;  1Q3A A;  1K7Q A;  1PWV A;  3LIK A;  2WOA A;  4XBH A;  1D8F A;  1CAQ A;  1A86 A;  3DPE A;  4A3W A;  3AIG A;  5I2Z A;  2X3A A;  1BM6 A;  3F1A A;  2V4B A;  1MMQ A;  3LUM A;  1EB6 A;  2A8H A;  3EDZ A;  3B8Z A;  2J83 A;  3LMC A;  4EFS A;  4R3V A;  1WNI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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