3KEKA

Crystal structure of human mmp-13 complexed with a (pyridin-4-yl)-2h-tetrazole compound
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
164
structure length
164
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Collagenase 3
publication title Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.
pubmed doi rcsb
source organism Homo sapiens
total genus 44
structure length 164
sequence length 164
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3kekA00
2OW1A 1CXVA 5D2BA 1R1HA 3LUNA 3KEJA 4PKRA 1C7KA 1KUFA 4G9LA 3V96B 3AIGA 3AYUA 3DWBA 1OS2A 3I7IA 3B2ZA 5B5PA 2POJA 1XFWA 2OVXA 4AYKA 1GO7P 1Y93A 3O2XA 1UMSA 3HDAP 1K7QA 3LUMA 2W12A 4A7BA 4XM8A 4GR3A 3DNGA 1OO9A 3U1RA 3K7NA 3F17A 3TSKA 1L6JA 1BUDA 1QJIA 2WOAA 1BUVM 1BQQM 4GWMA 1R1IA 1GKCA 2X7MA 5CXAA 3VI1A 3WV1A 1HFSA 3RTSA 3EHXA 3LE9A 5I43A 4H84A 1MMRA 1ZVXA 2OW0A 2W15A 2X3AA 3KWVC 4XM6A 5D1UA 1FM1A 4DV8A 4R3VA 1EAKA 5LABA 3Q2HA 2JNPA 1EB6A 1AF0A 2YIGA 2DDYA 1I1IP 1ZS0A 4GWNA 4ZR5A 2K2GA 4FXYP 1YP1A 1G4KA 1SLNA 2XS4A 1JAPA 4A3WA 1KUIA 1UTZA 1XURA 3EHYA 3I7GA 2CKIA 1MMPA 1RMZA 2JSDA 4DPEA 1XFXA 4IUWA 1HOVA 5L79A 2FV9A 3EDZA 3EDGA 3HYGA 3BA0A 2DW1A 1G12A 1BKCE 3LGPA 1B3DA 3HDBA 2D1OA 5H8XA 4AUOA 3EWJA 1JIZA 2OW2A 4XM7A 3LJTA 3LQ0A 1JIWP 2OY4A 4L63A 2WO8A 2V4BA 3UVCA 1QICA 2RJPA 4FU4A 2A8HA 1MMBA 4WZVA 1QIAA 4AIGA 3ZUKA 1YOUA 1JK3A 1BSWA 1XFZA 4PKSA 2ERQA 2L0RA 2OXWA 1YCMA 1D5JA 2OVZA 2MZEA 1JKYA 2X3CA 3LQBA 3MA2A 3LIKA 3CKIA 1FBLA 1SMPA 2MZHA 4AXQA 3B92A 4H2EA 1A85A 2O36A 2PJTA 3OHLA 4J4MA 4GR0A 456CA 2EROA 1ATLA 3GBOA 2E2DA 1O0QA 4H82A 3ZVSA 1ZXVA 3F19A 3F16A 4DF9A 2JT6A 3HY7A 5JMYA 1XFYA 2HU6A 4I35A 1QIBA 1CQRA 2J83A 5I12A 5I0LA 3KMCA 5I3MA 1IAAA 3KMEA 4GUYA 2Y6DA 3LEAA 3LKAA 1CGEA 1PWWA 3LJGA 4PKQA 3TS4A 2JT5A 3N2UA 2OXUA 1R1JA 4L6TA 1KUHA 2WO9A 5D1SA 1HV5A 4HMAA 1S4BP 2SRTA 1CGFA 5BOTA 2DW0A 2MLRA 1ROSA 3KECA 3Q2GA 1MNCA 4ON1A 1Q3AA 3K7LA 2MZIA 4PKUA 5CZMA 1XFUA 1A86A 2JIHA 2W0DA 2D1NA 1QUAA 4JQGA 1UEAA 2MLSA 3WV2A 2YB9A 3L0VA 1G05A 3F1AA 1BM6A 5L7FA 4WK7A 1AYKA 4IN9A 1K7GA 2N8RA 3EDIA 1IABA 1I76A 3OHOA 4FVLA 4JP4A 5I4OA 2OI0A 1FLSA 966CA 4PKVA 1XUDA 1BIWA 1HTDA 1OMJA 1J7NA 3B8ZA 2DDFA 3DSLA 1QJJA 3TT4A 2QPJA 5D7WA 4H76A 2O3EA 1DMTA 1WNIA 1JH1A 1C8TA 1R55A 4JA1A 4IJOA 4WKIA 2AIGP 4PKWA 4GR8A 1I73A 1KBCA 3LMCA 2DW2A 3ZXHA 4JPAA 5BOYA 2Z2DA 2E3XA 1D7XA 5CUHA 3P24A 5D1TA 1CGLA 1D8MA 1OM6A 1HY7A 4H3XA 1RM8A 3NX7A 1GE7A 1ZXCA 5BPAA 1JAQA 2OY2A 1SU3A 3G42A 4WF6A 1B8YA 4H30A 3O64A 1H71P 4CTHA 2W13A 1GO8P 3AYKA 1SLMA 1BKCI 1SATA 1Y8JA 4I03A 2FV5A 3ELMA 1ZP5A 1GXDA 4FXQA 1UTTA 3N2VA 1BQOA 2X3BA 1G49A 3USNA 1SRPA 1YQYA 1JAOA 2OW9A 1PWPA 1PWQA 1IADA 3EDHA 1ZTQA 1DTHA 2K9CA 3DPEA 1Z3JA 4EFSA 1JANA 4H49A 3SHIA 2ERPA 3E8RA 4H1QA 1PWVA 3L0TA 3LJZA 3KHIA 4L19A 2I47A 3G5CA 4GF1A 3F15A 4GQLA 1EUBA 2OZRA 4JIJA 2RJQA 3F18A 1GE5A 1CAQA 3P1VA 1UMTA 2Y6CA 2CLTA 1CIZA 1GE6A 1IAEA 2USNA 3LILA 4PKTA 1G9KA 3WV3A 1XFVA 3DL1A 5I2ZA 3HBUP 4WKEA 2W14A 1IAGA 4ILWD 830CA 1Y0VA 1O0TA 1K7IA 2TCLA 3LK8A 3HB2P 1USNA 1OM7A 3HY9A 3LIRA 3VTGA 2OXZA 1OM8A 1KUKA 1XUCA 1AKLA 3KEKA 3DPFA 2J0TA 1BKCA 4QKZA 1HFCA 1IACA 1MMQA 1ND1A 1KUGA 3TVCA 5B5OA 1BZSA 1GKDA 2XS3A 4HX3A 4XBHA 1ASTA 5D3CA 2AYKA 1JJ9A 4XCTA 1PWUA 3KRYA 3RTTA 1C3IA 1CK7A 1KAPP 4Q1LA 1OS9A 4DD8A 2KRJA 4G0DA 3HBVP 1R54A 1D8FA
chains in the Genus database with same CATH superfamily
2OW1A 1CXVA 5D2BA 1R1HA 3LUNA 3KEJA 4PKRA 1C7KA 1KUFA 4G9LA 3V96B 3AIGA 3AYUA 3DWBA 1OS2A 3I7IA 3B2ZA 5B5PA 1XM5A 2POJA 1XFWA 2OVXA 4AYKA 1GO7P 1Y93A 3O2XA 1UMSA 3HDAP 1K7QA 3LUMA 2W12A 4A7BA 4XM8A 4GR3A 3DNGA 1OO9A 3U1RA 3K7NA 3F17A 3TSKA 1L6JA 1BUDA 1QJIA 2WOAA 1BUVM 1BQQM 4GWMA 1R1IA 1GKCA 2X7MA 5CXAA 3VI1A 3DTKA 3WV1A 1HFSA 3RTSA 3EHXA 3LE9A 5I43A 4H84A 1MMRA 1ZVXA 2OW0A 2W15A 2X3AA 3KWVC 4XM6A 5D1UA 1FM1A 4DV8A 4R3VA 1EAKA 5LABA 3Q2HA 2JNPA 1EB6A 1AF0A 2YIGA 2DDYA 1I1IP 1ZS0A 4GWNA 4ZR5A 2K2GA 4FXYP 1YP1A 1G4KA 1SLNA 2XS4A 1JAPA 4A3WA 1KUIA 1UTZA 1XURA 3EHYA 3I7GA 2CKIA 1MMPA 1RMZA 2JSDA 4DPEA 1XFXA 4IUWA 1HOVA 5L79A 2FV9A 3EDZA 3EDGA 3HYGA 3BA0A 2DW1A 1G12A 1BKCE 3LGPA 1B3DA 3HDBA 2D1OA 5H8XA 4AUOA 3EWJA 1JIZA 2OW2A 4XM7A 3LJTA 3LQ0A 1JIWP 2OY4A 4L63A 2WO8A 2V4BA 3UVCA 1QICA 2RJPA 4FU4A 2A8HA 1MMBA 4WZVA 1QIAA 3DTEA 4AIGA 3ZUKA 1YOUA 1JK3A 1BSWA 1XFZA 4PKSA 2ERQA 2L0RA 2OXWA 1YCMA 1D5JA 2OVZA 2MZEA 1JKYA 2X3CA 3LQBA 3MA2A 3LIKA 3CKIA 1FBLA 1SMPA 2MZHA 4AXQA 3B92A 4H2EA 1A85A 2O36A 2PJTA 3OHLA 4J4MA 4GR0A 456CA 2EROA 1ATLA 3GBOA 2E2DA 1O0QA 4H82A 3ZVSA 1ZXVA 3F19A 3F16A 4DF9A 2JT6A 3HY7A 5JMYA 1XFYA 2HU6A 4I35A 1QIBA 1CQRA 2J83A 5I12A 5I0LA 3KMCA 5I3MA 1IAAA 3KMEA 4GUYA 2Y6DA 3LEAA 3LKAA 1CGEA 1PWWA 3LJGA 4PKQA 3TS4A 2JT5A 3N2UA 2OXUA 1R1JA 4L6TA 1KUHA 2WO9A 5D1SA 3DTIA 1HV5A 4HMAA 1S4BP 2SRTA 1CGFA 5BOTA 2DW0A 2MLRA 1ROSA 3KECA 3Q2GA 1MNCA 2YUFA 4ON1A 1Q3AA 3K7LA 2MZIA 4PKUA 5CZMA 1XFUA 1A86A 2JIHA 2W0DA 2D1NA 1QUAA 4JQGA 1UEAA 2MLSA 3WV2A 2YB9A 3L0VA 1G05A 3F1AA 1BM6A 5L7FA 4WK7A 1AYKA 4IN9A 1K7GA 2N8RA 3EDIA 1IABA 1I76A 3OHOA 4FVLA 4JP4A 5I4OA 2OI0A 1FLSA 966CA 4PKVA 1XUDA 1BIWA 1HTDA 1OMJA 1J7NA 3B8ZA 2DDFA 3DSLA 1QJJA 3TT4A 2QPJA 5D7WA 4H76A 2O3EA 1DMTA 1WNIA 1JH1A 1C8TA 1R55A 4JA1A 4IJOA 4WKIA 2AIGP 4PKWA 4GR8A 1I73A 1KBCA 3LMCA 2DW2A 3ZXHA 4JPAA 5BOYA 2Z2DA 2E3XA 1D7XA 5CUHA 3P24A 5D1TA 1CGLA 1D8MA 1OM6A 1HY7A 4H3XA 1RM8A 3NX7A 1GE7A 1ZXCA 5BPAA 1JAQA 2OY2A 1SU3A 3G42A 4WF6A 1B8YA 4H30A 3O64A 1H71P 4CTHA 2W13A 1GO8P 3AYKA 1SLMA 1BKCI 1SATA 1Y8JA 4I03A 2FV5A 3ELMA 1ZP5A 1GXDA 4FXQA 1UTTA 3N2VA 1BQOA 1OZ9A 2X3BA 1G49A 3USNA 1SRPA 1YQYA 1JAOA 1TVIA 2OW9A 1PWPA 1PWQA 1IADA 3EDHA 1ZTQA 1DTHA 2K9CA 3DPEA 1Z3JA 1XAXA 4EFSA 1JANA 4H49A 3SHIA 2ERPA 3E8RA 4H1QA 1PWVA 3L0TA 3LJZA 3KHIA 4L19A 2I47A 3G5CA 4GF1A 3F15A 4GQLA 1EUBA 2OZRA 4JIJA 2RJQA 3F18A 1GE5A 1CAQA 3P1VA 1UMTA 2Y6CA 2CLTA 1CIZA 1GE6A 1IAEA 2USNA 3LILA 4PKTA 1G9KA 3WV3A 1XFVA 3DL1A 5I2ZA 3HBUP 4WKEA 2W14A 1IAGA 4ILWD 830CA 1Y0VA 1O0TA 1K7IA 2TCLA 3LK8A 3HB2P 1USNA 4L7AA 1OM7A 3HY9A 3LIRA 3VTGA 2OXZA 1OM8A 1KUKA 1XUCA 1AKLA 3KEKA 3DPFA 2J0TA 1BKCA 4QKZA 1HFCA 1IACA 1MMQA 1ND1A 1KUGA 3TVCA 5B5OA 1BZSA 1GKDA 2XS3A 4HX3A 4XBHA 1ASTA 5D3CA 2AYKA 1JJ9A 4XCTA 1PWUA 3KRYA 3RTTA 1C3IA 1CK7A 1KAPP 4Q1LA 1OS9A 4DD8A 2KRJA 4G0DA 3HBVP 1R54A 1D8FA
chains in the Genus database with same CATH topology
2OW1A 1CXVA 5D2BA 1R1HA 3LUNA 3KEJA 4PKRA 1C7KA 1KUFA 4G9LA 3V96B 3AIGA 3AYUA 3DWBA 1OS2A 3I7IA 3B2ZA 5B5PA 2POJA 1XFWA 2OVXA 4AYKA 1GO7P 1Y93A 3O2XA 1UMSA 3HDAP 1K7QA 3LUMA 2W12A 4A7BA 4XM8A 4GR3A 3DNGA 1OO9A 3U1RA 3K7NA 3F17A 3TSKA 1L6JA 1BUDA 1QJIA 2WOAA 1BUVM 1BQQM 4GWMA 1R1IA 1GKCA 2X7MA 5CXAA 3VI1A 3DTKA 3WV1A 1HFSA 3RTSA 3EHXA 3LE9A 5I43A 4H84A 1MMRA 1ZVXA 2OW0A 2W15A 2X3AA 3KWVC 4XM6A 5D1UA 1FM1A 4DV8A 4R3VA 1EAKA 5LABA 3Q2HA 2JNPA 1EB6A 1AF0A 2YIGA 2DDYA 1I1IP 1ZS0A 4GWNA 4ZR5A 2K2GA 4FXYP 1YP1A 1G4KA 1SLNA 2XS4A 1JAPA 4A3WA 1KUIA 1UTZA 1XURA 3EHYA 3I7GA 2CKIA 1MMPA 1RMZA 2JSDA 4DPEA 1XFXA 4IUWA 1HOVA 5L79A 2FV9A 3EDZA 3EDGA 3HYGA 3BA0A 2DW1A 1G12A 1BKCE 3LGPA 1B3DA 3HDBA 2D1OA 5H8XA 4AUOA 3EWJA 1JIZA 2OW2A 4XM7A 3LJTA 3LQ0A 1JIWP 2OY4A 4L63A 2WO8A 2V4BA 3UVCA 1QICA 2RJPA 4FU4A 2A8HA 1MMBA 4WZVA 1QIAA 3DTEA 4AIGA 3ZUKA 1YOUA 1JK3A 1BSWA 1XFZA 4PKSA 2ERQA 2L0RA 2OXWA 1YCMA 1D5JA 2OVZA 2MZEA 1JKYA 2X3CA 3LQBA 3MA2A 3LIKA 3CKIA 1FBLA 1SMPA 2MZHA 4AXQA 3B92A 4H2EA 1A85A 2O36A 2PJTA 3OHLA 4J4MA 4GR0A 456CA 2EROA 1ATLA 3GBOA 2E2DA 1O0QA 4H82A 3ZVSA 1ZXVA 3F19A 3F16A 4DF9A 2JT6A 3HY7A 5JMYA 1XFYA 2HU6A 4I35A 1QIBA 1CQRA 2J83A 5I12A 5I0LA 3KMCA 5I3MA 1IAAA 3KMEA 4GUYA 2Y6DA 3LEAA 3LKAA 1CGEA 1PWWA 3LJGA 4PKQA 3TS4A 2JT5A 3N2UA 2OXUA 1R1JA 4L6TA 1KUHA 2WO9A 5D1SA 3DTIA 1HV5A 4HMAA 1S4BP 2SRTA 1CGFA 5BOTA 2DW0A 2MLRA 1ROSA 3KECA 3Q2GA 1MNCA 2YUFA 4ON1A 1Q3AA 3K7LA 2MZIA 4PKUA 5CZMA 1XFUA 1A86A 2JIHA 2W0DA 2D1NA 1QUAA 4JQGA 1UEAA 2MLSA 3WV2A 2YB9A 3L0VA 1G05A 3F1AA 1BM6A 5L7FA 4WK7A 1AYKA 4IN9A 1K7GA 2N8RA 3EDIA 1IABA 1I76A 3OHOA 4FVLA 4JP4A 5I4OA 2OI0A 1FLSA 966CA 4PKVA 1XUDA 1BIWA 1HTDA 1OMJA 1J7NA 3B8ZA 2DDFA 3DSLA 1QJJA 3TT4A 2QPJA 5D7WA 4H76A 2O3EA 1DMTA 1WNIA 1JH1A 1C8TA 1R55A 4JA1A 4IJOA 4WKIA 2AIGP 4PKWA 4GR8A 1I73A 1KBCA 3LMCA 2DW2A 3ZXHA 4JPAA 5BOYA 2Z2DA 2E3XA 1D7XA 5CUHA 3P24A 5D1TA 1CGLA 1D8MA 1OM6A 1HY7A 4H3XA 1RM8A 3NX7A 1GE7A 1ZXCA 5BPAA 1JAQA 2OY2A 1SU3A 3G42A 4WF6A 1B8YA 4H30A 3O64A 1H71P 4CTHA 2W13A 1GO8P 3AYKA 1SLMA 1BKCI 1SATA 1Y8JA 4I03A 2FV5A 3ELMA 1ZP5A 1GXDA 4FXQA 1UTTA 3N2VA 1BQOA 2X3BA 1G49A 3USNA 1SRPA 1YQYA 1JAOA 2OW9A 1PWPA 1PWQA 1IADA 3EDHA 1ZTQA 1DTHA 2K9CA 3DPEA 1Z3JA 4EFSA 1JANA 4H49A 3SHIA 2ERPA 3E8RA 4H1QA 1PWVA 3L0TA 3LJZA 3KHIA 4L19A 2I47A 3G5CA 4GF1A 3F15A 4GQLA 1EUBA 2OZRA 4JIJA 2RJQA 3F18A 1GE5A 1CAQA 3P1VA 1UMTA 2Y6CA 2CLTA 1CIZA 1GE6A 1IAEA 2USNA 3LILA 4PKTA 1G9KA 3WV3A 1XFVA 3DL1A 5I2ZA 3HBUP 4WKEA 2W14A 1IAGA 4ILWD 830CA 1Y0VA 1O0TA 1K7IA 2TCLA 3LK8A 3HB2P 1USNA 4L7AA 1OM7A 3HY9A 3LIRA 3VTGA 2OXZA 1OM8A 1KUKA 1XUCA 1AKLA 3KEKA 3DPFA 2J0TA 1BKCA 4QKZA 1HFCA 1IACA 1MMQA 1ND1A 1KUGA 3TVCA 5B5OA 1BZSA 1GKDA 2XS3A 4HX3A 4XBHA 1ASTA 5D3CA 2AYKA 1JJ9A 4XCTA 1PWUA 3KRYA 3RTTA 1C3IA 1CK7A 1KAPP 4Q1LA 1OS9A 4DD8A 2KRJA 4G0DA 3HBVP 1R54A 1D8FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OW1 A;  1CXV A;  5D2B A;  1R1H A;  3LUN A;  3KEJ A;  4PKR A;  1C7K A;  1KUF A;  4G9L A;  3V96 B;  3AIG A;  3AYU A;  3DWB A;  1OS2 A;  3I7I A;  3B2Z A;  5B5P A;  2POJ A;  1XFW A;  2OVX A;  4AYK A;  1GO7 P;  1Y93 A;  3O2X A;  1UMS A;  3HDA P;  1K7Q A;  3LUM A;  2W12 A;  4A7B A;  4XM8 A;  4GR3 A;  3DNG A;  1OO9 A;  3U1R A;  3K7N A;  3F17 A;  3TSK A;  1L6J A;  1BUD A;  1QJI A;  2WOA A;  1BUV M;  1BQQ M;  4GWM A;  1R1I A;  1GKC A;  2X7M A;  5CXA A;  3VI1 A;  3WV1 A;  1HFS A;  3RTS A;  3EHX A;  3LE9 A;  5I43 A;  4H84 A;  1MMR A;  1ZVX A;  2OW0 A;  2W15 A;  2X3A A;  3KWV C;  4XM6 A;  5D1U A;  1FM1 A;  4DV8 A;  4R3V A;  1EAK A;  5LAB A;  3Q2H A;  2JNP A;  1EB6 A;  1AF0 A;  2YIG A;  2DDY A;  1I1I P;  1ZS0 A;  4GWN A;  4ZR5 A;  2K2G A;  4FXY P;  1YP1 A;  1G4K A;  1SLN A;  2XS4 A;  1JAP A;  4A3W A;  1KUI A;  1UTZ A;  1XUR A;  3EHY A;  3I7G A;  2CKI A;  1MMP A;  1RMZ A;  2JSD A;  4DPE A;  1XFX A;  4IUW A;  1HOV A;  5L79 A;  2FV9 A;  3EDZ A;  3EDG A;  3HYG A;  3BA0 A;  2DW1 A;  1G12 A;  1BKC E;  3LGP A;  1B3D A;  3HDB A;  2D1O A;  5H8X A;  4AUO A;  3EWJ A;  1JIZ A;  2OW2 A;  4XM7 A;  3LJT A;  3LQ0 A;  1JIW P;  2OY4 A;  4L63 A;  2WO8 A;  2V4B A;  3UVC A;  1QIC A;  2RJP A;  4FU4 A;  2A8H A;  1MMB A;  4WZV A;  1QIA A;  4AIG A;  3ZUK A;  1YOU A;  1JK3 A;  1BSW A;  1XFZ A;  4PKS A;  2ERQ A;  2L0R A;  2OXW A;  1YCM A;  1D5J A;  2OVZ A;  2MZE A;  1JKY A;  2X3C A;  3LQB A;  3MA2 A;  3LIK A;  3CKI A;  1FBL A;  1SMP A;  2MZH A;  4AXQ A;  3B92 A;  4H2E A;  1A85 A;  2O36 A;  2PJT A;  3OHL A;  4J4M A;  4GR0 A;  456C A;  2ERO A;  1ATL A;  3GBO A;  2E2D A;  1O0Q A;  4H82 A;  3ZVS A;  1ZXV A;  3F19 A;  3F16 A;  4DF9 A;  2JT6 A;  3HY7 A;  5JMY A;  1XFY A;  2HU6 A;  4I35 A;  1QIB A;  1CQR A;  2J83 A;  5I12 A;  5I0L A;  3KMC A;  5I3M A;  1IAA A;  3KME A;  4GUY A;  2Y6D A;  3LEA A;  3LKA A;  1CGE A;  1PWW A;  3LJG A;  4PKQ A;  3TS4 A;  2JT5 A;  3N2U A;  2OXU A;  1R1J A;  4L6T A;  1KUH A;  2WO9 A;  5D1S A;  1HV5 A;  4HMA A;  1S4B P;  2SRT A;  1CGF A;  5BOT A;  2DW0 A;  2MLR A;  1ROS A;  3KEC A;  3Q2G A;  1MNC A;  4ON1 A;  1Q3A A;  3K7L A;  2MZI A;  4PKU A;  5CZM A;  1XFU A;  1A86 A;  2JIH A;  2W0D A;  2D1N A;  1QUA A;  4JQG A;  1UEA A;  2MLS A;  3WV2 A;  2YB9 A;  3L0V A;  1G05 A;  3F1A A;  1BM6 A;  5L7F A;  4WK7 A;  1AYK A;  4IN9 A;  1K7G A;  2N8R A;  3EDI A;  1IAB A;  1I76 A;  3OHO A;  4FVL A;  4JP4 A;  5I4O A;  2OI0 A;  1FLS A;  966C A;  4PKV A;  1XUD A;  1BIW A;  1HTD A;  1OMJ A;  1J7N A;  3B8Z A;  2DDF A;  3DSL A;  1QJJ A;  3TT4 A;  2QPJ A;  5D7W A;  4H76 A;  2O3E A;  1DMT A;  1WNI A;  1JH1 A;  1C8T A;  1R55 A;  4JA1 A;  4IJO A;  4WKI A;  2AIG P;  4PKW A;  4GR8 A;  1I73 A;  1KBC A;  3LMC A;  2DW2 A;  3ZXH A;  4JPA A;  5BOY A;  2Z2D A;  2E3X A;  1D7X A;  5CUH A;  3P24 A;  5D1T A;  1CGL A;  1D8M A;  1OM6 A;  1HY7 A;  4H3X A;  1RM8 A;  3NX7 A;  1GE7 A;  1ZXC A;  5BPA A;  1JAQ A;  2OY2 A;  1SU3 A;  3G42 A;  4WF6 A;  1B8Y A;  4H30 A;  3O64 A;  1H71 P;  4CTH A;  2W13 A;  1GO8 P;  3AYK A;  1SLM A;  1BKC I;  1SAT A;  1Y8J A;  4I03 A;  2FV5 A;  3ELM A;  1ZP5 A;  1GXD A;  4FXQ A;  1UTT A;  3N2V A;  1BQO A;  2X3B A;  1G49 A;  3USN A;  1SRP A;  1YQY A;  1JAO A;  2OW9 A;  1PWP A;  1PWQ A;  1IAD A;  3EDH A;  1ZTQ A;  1DTH A;  2K9C A;  3DPE A;  1Z3J A;  4EFS A;  1JAN A;  4H49 A;  3SHI A;  2ERP A;  3E8R A;  4H1Q A;  1PWV A;  3L0T A;  3LJZ A;  3KHI A;  4L19 A;  2I47 A;  3G5C A;  4GF1 A;  3F15 A;  4GQL A;  1EUB A;  2OZR A;  4JIJ A;  2RJQ A;  3F18 A;  1GE5 A;  1CAQ A;  3P1V A;  1UMT A;  2Y6C A;  2CLT A;  1CIZ A;  1GE6 A;  1IAE A;  2USN A;  3LIL A;  4PKT A;  1G9K A;  3WV3 A;  1XFV A;  3DL1 A;  5I2Z A;  3HBU P;  4WKE A;  2W14 A;  1IAG A;  4ILW D;  830C A;  1Y0V A;  1O0T A;  1K7I A;  2TCL A;  3LK8 A;  3HB2 P;  1USN A;  1OM7 A;  3HY9 A;  3LIR A;  3VTG A;  2OXZ A;  1OM8 A;  1KUK A;  1XUC A;  1AKL A;  3KEK A;  3DPF A;  2J0T A;  1BKC A;  4QKZ A;  1HFC A;  1IAC A;  1MMQ A;  1ND1 A;  1KUG A;  3TVC A;  5B5O A;  1BZS A;  1GKD A;  2XS3 A;  4HX3 A;  4XBH A;  1AST A;  5D3C A;  2AYK A;  1JJ9 A;  4XCT A;  1PWU A;  3KRY A;  3RTT A;  1C3I A;  1CK7 A;  1KAP P;  4Q1L A;  1OS9 A;  4DD8 A;  2KRJ A;  4G0D A;  3HBV P;  1R54 A;  1D8F A; 
#chains in the Genus database with same CATH topology
 2OW1 A;  1CXV A;  5D2B A;  1R1H A;  3LUN A;  3KEJ A;  4PKR A;  1C7K A;  1KUF A;  4G9L A;  3V96 B;  3AIG A;  3AYU A;  3DWB A;  1OS2 A;  3I7I A;  3B2Z A;  5B5P A;  1XM5 A;  2POJ A;  1XFW A;  2OVX A;  4AYK A;  1GO7 P;  1Y93 A;  3O2X A;  1UMS A;  3HDA P;  1K7Q A;  3LUM A;  2W12 A;  4A7B A;  4XM8 A;  4GR3 A;  3DNG A;  1OO9 A;  3U1R A;  3K7N A;  3F17 A;  3TSK A;  1L6J A;  1BUD A;  1QJI A;  2WOA A;  1BUV M;  1BQQ M;  4GWM A;  1R1I A;  1GKC A;  2X7M A;  5CXA A;  3VI1 A;  3DTK A;  3WV1 A;  1HFS A;  3RTS A;  3EHX A;  3LE9 A;  5I43 A;  4H84 A;  1MMR A;  1ZVX A;  2OW0 A;  2W15 A;  2X3A A;  3KWV C;  4XM6 A;  5D1U A;  1FM1 A;  4DV8 A;  4R3V A;  1EAK A;  5LAB A;  3Q2H A;  2JNP A;  1EB6 A;  1AF0 A;  2YIG A;  2DDY A;  1I1I P;  1ZS0 A;  4GWN A;  4ZR5 A;  2K2G A;  4FXY P;  1YP1 A;  1G4K A;  1SLN A;  2XS4 A;  1JAP A;  4A3W A;  1KUI A;  1UTZ A;  1XUR A;  3EHY A;  3I7G A;  2CKI A;  1MMP A;  1RMZ A;  2JSD A;  4DPE A;  1XFX A;  4IUW A;  1HOV A;  5L79 A;  2FV9 A;  3EDZ A;  3EDG A;  3HYG A;  3BA0 A;  2DW1 A;  1G12 A;  1BKC E;  3LGP A;  1B3D A;  3HDB A;  2D1O A;  5H8X A;  4AUO A;  3EWJ A;  1JIZ A;  2OW2 A;  4XM7 A;  3LJT A;  3LQ0 A;  1JIW P;  2OY4 A;  4L63 A;  2WO8 A;  2V4B A;  3UVC A;  1QIC A;  2RJP A;  4FU4 A;  2A8H A;  1MMB A;  4WZV A;  1QIA A;  3DTE A;  4AIG A;  3ZUK A;  1YOU A;  1JK3 A;  1BSW A;  1XFZ A;  4PKS A;  2ERQ A;  2L0R A;  2OXW A;  1YCM A;  1D5J A;  2OVZ A;  2MZE A;  1JKY A;  2X3C A;  3LQB A;  3MA2 A;  3LIK A;  3CKI A;  1FBL A;  1SMP A;  2MZH A;  4AXQ A;  3B92 A;  4H2E A;  1A85 A;  2O36 A;  2PJT A;  3OHL A;  4J4M A;  4GR0 A;  456C A;  2ERO A;  1ATL A;  3GBO A;  2E2D A;  1O0Q A;  4H82 A;  3ZVS A;  1ZXV A;  3F19 A;  3F16 A;  4DF9 A;  2JT6 A;  3HY7 A;  5JMY A;  1XFY A;  2HU6 A;  4I35 A;  1QIB A;  1CQR A;  2J83 A;  5I12 A;  5I0L A;  3KMC A;  5I3M A;  1IAA A;  3KME A;  4GUY A;  2Y6D A;  3LEA A;  3LKA A;  1CGE A;  1PWW A;  3LJG A;  4PKQ A;  3TS4 A;  2JT5 A;  3N2U A;  2OXU A;  1R1J A;  4L6T A;  1KUH A;  2WO9 A;  5D1S A;  3DTI A;  1HV5 A;  4HMA A;  1S4B P;  2SRT A;  1CGF A;  5BOT A;  2DW0 A;  2MLR A;  1ROS A;  3KEC A;  3Q2G A;  1MNC A;  2YUF A;  4ON1 A;  1Q3A A;  3K7L A;  2MZI A;  4PKU A;  5CZM A;  1XFU A;  1A86 A;  2JIH A;  2W0D A;  2D1N A;  1QUA A;  4JQG A;  1UEA A;  2MLS A;  3WV2 A;  2YB9 A;  3L0V A;  1G05 A;  3F1A A;  1BM6 A;  5L7F A;  4WK7 A;  1AYK A;  4IN9 A;  1K7G A;  2N8R A;  3EDI A;  1IAB A;  1I76 A;  3OHO A;  4FVL A;  4JP4 A;  5I4O A;  2OI0 A;  1FLS A;  966C A;  4PKV A;  1XUD A;  1BIW A;  1HTD A;  1OMJ A;  1J7N A;  3B8Z A;  2DDF A;  3DSL A;  1QJJ A;  3TT4 A;  2QPJ A;  5D7W A;  4H76 A;  2O3E A;  1DMT A;  1WNI A;  1JH1 A;  1C8T A;  1R55 A;  4JA1 A;  4IJO A;  4WKI A;  2AIG P;  4PKW A;  4GR8 A;  1I73 A;  1KBC A;  3LMC A;  2DW2 A;  3ZXH A;  4JPA A;  5BOY A;  2Z2D A;  2E3X A;  1D7X A;  5CUH A;  3P24 A;  5D1T A;  1CGL A;  1D8M A;  1OM6 A;  1HY7 A;  4H3X A;  1RM8 A;  3NX7 A;  1GE7 A;  1ZXC A;  5BPA A;  1JAQ A;  2OY2 A;  1SU3 A;  3G42 A;  4WF6 A;  1B8Y A;  4H30 A;  3O64 A;  1H71 P;  4CTH A;  2W13 A;  1GO8 P;  3AYK A;  1SLM A;  1BKC I;  1SAT A;  1Y8J A;  4I03 A;  2FV5 A;  3ELM A;  1ZP5 A;  1GXD A;  4FXQ A;  1UTT A;  3N2V A;  1BQO A;  1OZ9 A;  2X3B A;  1G49 A;  3USN A;  1SRP A;  1YQY A;  1JAO A;  1TVI A;  2OW9 A;  1PWP A;  1PWQ A;  1IAD A;  3EDH A;  1ZTQ A;  1DTH A;  2K9C A;  3DPE A;  1Z3J A;  1XAX A;  4EFS A;  1JAN A;  4H49 A;  3SHI A;  2ERP A;  3E8R A;  4H1Q A;  1PWV A;  3L0T A;  3LJZ A;  3KHI A;  4L19 A;  2I47 A;  3G5C A;  4GF1 A;  3F15 A;  4GQL A;  1EUB A;  2OZR A;  4JIJ A;  2RJQ A;  3F18 A;  1GE5 A;  1CAQ A;  3P1V A;  1UMT A;  2Y6C A;  2CLT A;  1CIZ A;  1GE6 A;  1IAE A;  2USN A;  3LIL A;  4PKT A;  1G9K A;  3WV3 A;  1XFV A;  3DL1 A;  5I2Z A;  3HBU P;  4WKE A;  2W14 A;  1IAG A;  4ILW D;  830C A;  1Y0V A;  1O0T A;  1K7I A;  2TCL A;  3LK8 A;  3HB2 P;  1USN A;  4L7A A;  1OM7 A;  3HY9 A;  3LIR A;  3VTG A;  2OXZ A;  1OM8 A;  1KUK A;  1XUC A;  1AKL A;  3KEK A;  3DPF A;  2J0T A;  1BKC A;  4QKZ A;  1HFC A;  1IAC A;  1MMQ A;  1ND1 A;  1KUG A;  3TVC A;  5B5O A;  1BZS A;  1GKD A;  2XS3 A;  4HX3 A;  4XBH A;  1AST A;  5D3C A;  2AYK A;  1JJ9 A;  4XCT A;  1PWU A;  3KRY A;  3RTT A;  1C3I A;  1CK7 A;  1KAP P;  4Q1L A;  1OS9 A;  4DD8 A;  2KRJ A;  4G0D A;  3HBV P;  1R54 A;  1D8F A; 
#chains in the Genus database with same CATH homology
 2OW1 A;  1CXV A;  5D2B A;  1R1H A;  3LUN A;  3KEJ A;  4PKR A;  1C7K A;  1KUF A;  4G9L A;  3V96 B;  3AIG A;  3AYU A;  3DWB A;  1OS2 A;  3I7I A;  3B2Z A;  5B5P A;  2POJ A;  1XFW A;  2OVX A;  4AYK A;  1GO7 P;  1Y93 A;  3O2X A;  1UMS A;  3HDA P;  1K7Q A;  3LUM A;  2W12 A;  4A7B A;  4XM8 A;  4GR3 A;  3DNG A;  1OO9 A;  3U1R A;  3K7N A;  3F17 A;  3TSK A;  1L6J A;  1BUD A;  1QJI A;  2WOA A;  1BUV M;  1BQQ M;  4GWM A;  1R1I A;  1GKC A;  2X7M A;  5CXA A;  3VI1 A;  3DTK A;  3WV1 A;  1HFS A;  3RTS A;  3EHX A;  3LE9 A;  5I43 A;  4H84 A;  1MMR A;  1ZVX A;  2OW0 A;  2W15 A;  2X3A A;  3KWV C;  4XM6 A;  5D1U A;  1FM1 A;  4DV8 A;  4R3V A;  1EAK A;  5LAB A;  3Q2H A;  2JNP A;  1EB6 A;  1AF0 A;  2YIG A;  2DDY A;  1I1I P;  1ZS0 A;  4GWN A;  4ZR5 A;  2K2G A;  4FXY P;  1YP1 A;  1G4K A;  1SLN A;  2XS4 A;  1JAP A;  4A3W A;  1KUI A;  1UTZ A;  1XUR A;  3EHY A;  3I7G A;  2CKI A;  1MMP A;  1RMZ A;  2JSD A;  4DPE A;  1XFX A;  4IUW A;  1HOV A;  5L79 A;  2FV9 A;  3EDZ A;  3EDG A;  3HYG A;  3BA0 A;  2DW1 A;  1G12 A;  1BKC E;  3LGP A;  1B3D A;  3HDB A;  2D1O A;  5H8X A;  4AUO A;  3EWJ A;  1JIZ A;  2OW2 A;  4XM7 A;  3LJT A;  3LQ0 A;  1JIW P;  2OY4 A;  4L63 A;  2WO8 A;  2V4B A;  3UVC A;  1QIC A;  2RJP A;  4FU4 A;  2A8H A;  1MMB A;  4WZV A;  1QIA A;  3DTE A;  4AIG A;  3ZUK A;  1YOU A;  1JK3 A;  1BSW A;  1XFZ A;  4PKS A;  2ERQ A;  2L0R A;  2OXW A;  1YCM A;  1D5J A;  2OVZ A;  2MZE A;  1JKY A;  2X3C A;  3LQB A;  3MA2 A;  3LIK A;  3CKI A;  1FBL A;  1SMP A;  2MZH A;  4AXQ A;  3B92 A;  4H2E A;  1A85 A;  2O36 A;  2PJT A;  3OHL A;  4J4M A;  4GR0 A;  456C A;  2ERO A;  1ATL A;  3GBO A;  2E2D A;  1O0Q A;  4H82 A;  3ZVS A;  1ZXV A;  3F19 A;  3F16 A;  4DF9 A;  2JT6 A;  3HY7 A;  5JMY A;  1XFY A;  2HU6 A;  4I35 A;  1QIB A;  1CQR A;  2J83 A;  5I12 A;  5I0L A;  3KMC A;  5I3M A;  1IAA A;  3KME A;  4GUY A;  2Y6D A;  3LEA A;  3LKA A;  1CGE A;  1PWW A;  3LJG A;  4PKQ A;  3TS4 A;  2JT5 A;  3N2U A;  2OXU A;  1R1J A;  4L6T A;  1KUH A;  2WO9 A;  5D1S A;  3DTI A;  1HV5 A;  4HMA A;  1S4B P;  2SRT A;  1CGF A;  5BOT A;  2DW0 A;  2MLR A;  1ROS A;  3KEC A;  3Q2G A;  1MNC A;  2YUF A;  4ON1 A;  1Q3A A;  3K7L A;  2MZI A;  4PKU A;  5CZM A;  1XFU A;  1A86 A;  2JIH A;  2W0D A;  2D1N A;  1QUA A;  4JQG A;  1UEA A;  2MLS A;  3WV2 A;  2YB9 A;  3L0V A;  1G05 A;  3F1A A;  1BM6 A;  5L7F A;  4WK7 A;  1AYK A;  4IN9 A;  1K7G A;  2N8R A;  3EDI A;  1IAB A;  1I76 A;  3OHO A;  4FVL A;  4JP4 A;  5I4O A;  2OI0 A;  1FLS A;  966C A;  4PKV A;  1XUD A;  1BIW A;  1HTD A;  1OMJ A;  1J7N A;  3B8Z A;  2DDF A;  3DSL A;  1QJJ A;  3TT4 A;  2QPJ A;  5D7W A;  4H76 A;  2O3E A;  1DMT A;  1WNI A;  1JH1 A;  1C8T A;  1R55 A;  4JA1 A;  4IJO A;  4WKI A;  2AIG P;  4PKW A;  4GR8 A;  1I73 A;  1KBC A;  3LMC A;  2DW2 A;  3ZXH A;  4JPA A;  5BOY A;  2Z2D A;  2E3X A;  1D7X A;  5CUH A;  3P24 A;  5D1T A;  1CGL A;  1D8M A;  1OM6 A;  1HY7 A;  4H3X A;  1RM8 A;  3NX7 A;  1GE7 A;  1ZXC A;  5BPA A;  1JAQ A;  2OY2 A;  1SU3 A;  3G42 A;  4WF6 A;  1B8Y A;  4H30 A;  3O64 A;  1H71 P;  4CTH A;  2W13 A;  1GO8 P;  3AYK A;  1SLM A;  1BKC I;  1SAT A;  1Y8J A;  4I03 A;  2FV5 A;  3ELM A;  1ZP5 A;  1GXD A;  4FXQ A;  1UTT A;  3N2V A;  1BQO A;  2X3B A;  1G49 A;  3USN A;  1SRP A;  1YQY A;  1JAO A;  2OW9 A;  1PWP A;  1PWQ A;  1IAD A;  3EDH A;  1ZTQ A;  1DTH A;  2K9C A;  3DPE A;  1Z3J A;  4EFS A;  1JAN A;  4H49 A;  3SHI A;  2ERP A;  3E8R A;  4H1Q A;  1PWV A;  3L0T A;  3LJZ A;  3KHI A;  4L19 A;  2I47 A;  3G5C A;  4GF1 A;  3F15 A;  4GQL A;  1EUB A;  2OZR A;  4JIJ A;  2RJQ A;  3F18 A;  1GE5 A;  1CAQ A;  3P1V A;  1UMT A;  2Y6C A;  2CLT A;  1CIZ A;  1GE6 A;  1IAE A;  2USN A;  3LIL A;  4PKT A;  1G9K A;  3WV3 A;  1XFV A;  3DL1 A;  5I2Z A;  3HBU P;  4WKE A;  2W14 A;  1IAG A;  4ILW D;  830C A;  1Y0V A;  1O0T A;  1K7I A;  2TCL A;  3LK8 A;  3HB2 P;  1USN A;  4L7A A;  1OM7 A;  3HY9 A;  3LIR A;  3VTG A;  2OXZ A;  1OM8 A;  1KUK A;  1XUC A;  1AKL A;  3KEK A;  3DPF A;  2J0T A;  1BKC A;  4QKZ A;  1HFC A;  1IAC A;  1MMQ A;  1ND1 A;  1KUG A;  3TVC A;  5B5O A;  1BZS A;  1GKD A;  2XS3 A;  4HX3 A;  4XBH A;  1AST A;  5D3C A;  2AYK A;  1JJ9 A;  4XCT A;  1PWU A;  3KRY A;  3RTT A;  1C3I A;  1CK7 A;  1KAP P;  4Q1L A;  1OS9 A;  4DD8 A;  2KRJ A;  4G0D A;  3HBV P;  1R54 A;  1D8F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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