2W0DA

Does a fast nuclear magnetic resonance spectroscopy- and x-ray crystallography hybrid approach provide reliable structural information of ligand-protein complexes? a case study of metalloproteinases.
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHAIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Does a Fast Nuclear Magnetic Resonance Spectroscopy- and X-Ray Crystallography Hybrid Approach Provide Reliable Structural Information of Ligand-Protein Complexes? a Case Study of Metalloproteinases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords MACROPHAGE METALLOELASTASE
total genus 47
structure length 158
sequence length 158
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2008-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2w0dA00
1ATLA 2USNA 3LE9A 1MMBA 1D5JA 4XM8A 2E3XA 2YIGA 1K7QA 2WO8A 4IN9A 1HY7A 5I3MA 4PKRA 1EB6A 2Z2DA 5B5OA 5CUHA 4H30A 4ON1A 4WK7A 1D8FA 2JSDA 3LUMA 1IAAA 3DPEA 1C7KA 1S4BP 1GXDA 3AIGA 3EDHA 4DD8A 1XFXA 2Y6CA 4PKVA 1CXVA 2DW0A 1XFVA 2DDYA 5BOYA 1ZXVA 3LJGA 4JPAA 3P1VA 3HDAP 1CGFA 1PWQA 2WOAA 2ERPA 2EROA 1HTDA 2J83A 5B5PA 1CAQA 2FV5A 1C8TA 1Y0VA 3EHYA 3B2ZA 4XBHA 1CGLA 1SLNA 1Y93A 1AKLA 1D7XA 2OVZA 2MZHA 1R1IA 1Y8JA 2OW1A 1QUAA 4A3WA 830CA 2MZIA 3I7GA 1YCMA 966CA 1SU3A 4G9LA 5D1SA 1A86A 1R1JA 1GKCA 3LQ0A 1JANA 1MMQA 1O0TA 2A8HA 1C3IA 1XFUA 2I47A 2OY2A 3LJTA 3F1AA 1D8MA 4QKZA 1JAOA 1G12A 3G42A 2K2GA 2X7MA 3GBOA 3U1RA 1IABA 1UMTA 4DPEA 3HYGA 3ZUKA 3VI1A 1DTHA 1XFWA 2D1NA 5I2ZA 5L7FA 2OXWA 3KEKA 4H82A 3F15A 1I73A 2XS3A 2KRJA 3N2UA 1CK7A 2DDFA 1KUKA 4HMAA 1A85A 2JNPA 4AYKA 3AYKA 3ZXHA 1BUVM 1UTTA 3OHOA 3O64A 1G05A 2XS4A 1KUGA 4GR8A 3F18A 1FBLA 1IAEA 4I35A 3SHIA 3KWVC 5D7WA 2O3EA 2ERQA 1OS9A 4WZVA 1XUCA 1OM8A 5LABA 2FV9A 2MLRA 1QICA 2OI0A 4DF9A 1XFYA 2AIGP 4JQGA 3OHLA 1EAKA 2HU6A 4DV8A 4JP4A 4GUYA 3WV3A 3UVCA 1R1HA 1EUBA 3Q2GA 1ASTA 1B3DA 3AYUA 3LQBA 4IJOA 1JIZA 1K7IA 1CGEA 1FLSA 5I0LA 1XFZA 1MMPA 2OY4A 3LIRA 3DWBA 3L0VA 2K9CA 1GE7A 1I76A 1FM1A 1BQQM 1JH1A 1BIWA 1UTZA 3TVCA 1GKDA 1JKYA 3LMCA 2X3BA 3G5CA 4GQLA 2QPJA 1K7GA 3N2VA 3Q2HA 1UEAA 5JMYA 4GWNA 1KUFA 3TSKA 1JAQA 4H49A 1XUDA 4CTHA 1GE6A 1PWVA 1KBCA 1OM6A 1USNA 3ZVSA 1G4KA 2W13A 1QIBA 4H1QA 2D1OA 2OXZA 1BZSA 1Q3AA 2RJPA 1RM8A 3EWJA 3TT4A 1G9KA 1UMSA 1ZVXA 3HY7A 1R54A 1GO7P 2TCLA 1YQYA 3LUNA 2X3CA 1AYKA 1KUIA 3NX7A 1BKCE 4GWMA 4WF6A 1PWWA 4GR0A 1QJJA 1OS2A 5BOTA 3KEJA 4FVLA 3E8RA 2RJQA 4AUOA 2OW9A 5L79A 4I03A 3DL1A 1YP1A 1BSWA 3HY9A 1WNIA 5CXAA 4AIGA 1JAPA 4H84A 1BKCI 1OMJA 1YOUA 2DW2A 1JIWP 3WV1A 3KMEA 3DSLA 3O2XA 1L6JA 3KECA 3BA0A 3LIKA 2OW0A 1PWUA 4IUWA 1ZXCA 5BPAA 3LGPA 4JIJA 4AXQA 3I7IA 1IAGA 2JT6A 1AF0A 2W12A 1KUHA 2E2DA 3DPFA 1IADA 3P24A 2W0DA 3EDZA 2O36A 1HOVA 3EHXA 1DMTA 2Y6DA 2OW2A 4ILWD 1GO8P 1IACA 3LJZA 1SLMA 2DW1A 1R55A 2OVXA 4GF1A 2JIHA 1GE5A 3HBUP 1HV5A 1JJ9A 5I4OA 3HDBA 4Q1LA 1BM6A 3K7LA 5D2BA 2V4BA 1J7NA 3F19A 2YB9A 2POJA 3CKIA 4H2EA 4XM6A 3V96B 3TS4A 3LEAA 1ND1A 1BKCA 1RMZA 1ZP5A 5CZMA 2W15A 3KHIA 1ROSA 4WKIA 1XURA 2MLSA 5H8XA 4L6TA 3ELMA 456CA 2MZEA 3WV2A 3MA2A 1H71P 4EFSA 3K7NA 1SMPA 4PKUA 3B92A 3LKAA 3KMCA 4PKTA 5D3CA 3EDGA 4H3XA 1B8YA 4GR3A 1MMRA 1G49A 4XCTA 4G0DA 4PKSA 1JK3A 3DNGA 2AYKA 1ZS0A 4FU4A 5D1TA 1HFCA 3HBVP 2OZRA 4FXYP 4ZR5A 3LILA 4L19A 1PWPA 2OXUA 2PJTA 5I12A 1ZTQA 3F16A 1CQRA 3RTTA 1Z3JA 1HFSA 4R3VA 4J4MA 1OM7A 1SRPA 3LK8A 2JT5A 4PKQA 3F17A 3KRYA 4A7BA 2J0TA 3USNA 1QJIA 4L63A 1BUDA 2L0RA 4HX3A 3VTGA 2N8RA 2X3AA 4JA1A 5I43A 2W14A 5D1UA 3HB2P 1O0QA 1CIZA 1BQOA 1MNCA 4FXQA 4H76A 1QIAA 3L0TA 1I1IP 4XM7A 2CKIA 3RTSA 1KAPP 1SATA 2WO9A 4PKWA 1OO9A 2SRTA 4WKEA 3EDIA 2CLTA 3B8ZA
chains in the Genus database with same CATH superfamily
1ATLA 2USNA 3LE9A 1MMBA 1D5JA 4XM8A 2E3XA 2YIGA 1K7QA 2WO8A 4IN9A 1HY7A 5I3MA 4PKRA 1EB6A 2Z2DA 5B5OA 5CUHA 4H30A 4ON1A 4WK7A 1D8FA 2JSDA 3LUMA 1IAAA 3DPEA 1C7KA 1S4BP 1GXDA 3AIGA 3EDHA 4DD8A 1XFXA 2Y6CA 4PKVA 1CXVA 2DW0A 1XFVA 2DDYA 5BOYA 1ZXVA 3LJGA 4JPAA 3P1VA 3HDAP 1CGFA 1PWQA 2WOAA 2ERPA 2EROA 1HTDA 2J83A 5B5PA 1CAQA 2FV5A 1C8TA 1Y0VA 3EHYA 3B2ZA 4XBHA 1CGLA 1SLNA 1Y93A 1AKLA 1D7XA 2OVZA 2MZHA 1R1IA 1Y8JA 2YUFA 2OW1A 1QUAA 3DTKA 4A3WA 830CA 2MZIA 3I7GA 1YCMA 966CA 1SU3A 4G9LA 5D1SA 1A86A 1R1JA 1GKCA 3LQ0A 1JANA 1MMQA 1O0TA 2A8HA 1C3IA 1XM5A 1XFUA 2I47A 2OY2A 3LJTA 3DTIA 3F1AA 1D8MA 4QKZA 1JAOA 1G12A 3G42A 2K2GA 2X7MA 3GBOA 3U1RA 1IABA 1UMTA 4DPEA 3HYGA 3ZUKA 3VI1A 1DTHA 1XFWA 2D1NA 5I2ZA 5L7FA 2OXWA 3KEKA 4H82A 3F15A 1I73A 2XS3A 2KRJA 3N2UA 1CK7A 2DDFA 1KUKA 4HMAA 1A85A 2JNPA 4AYKA 3AYKA 3ZXHA 1BUVM 1UTTA 3OHOA 3O64A 1G05A 2XS4A 1KUGA 4GR8A 3F18A 1FBLA 1IAEA 4I35A 3SHIA 3KWVC 5D7WA 2O3EA 2ERQA 1OS9A 4WZVA 1XUCA 1OM8A 5LABA 2FV9A 2MLRA 1QICA 2OI0A 4DF9A 1XFYA 2AIGP 4JQGA 3OHLA 1EAKA 2HU6A 4DV8A 4JP4A 4GUYA 3WV3A 3UVCA 1R1HA 1EUBA 3Q2GA 1ASTA 1B3DA 3AYUA 3LQBA 4IJOA 1JIZA 1K7IA 1CGEA 1FLSA 5I0LA 1XFZA 1MMPA 2OY4A 3LIRA 3DWBA 3L0VA 2K9CA 1GE7A 1I76A 1FM1A 1BQQM 1JH1A 1BIWA 1UTZA 3TVCA 1GKDA 1JKYA 3LMCA 2X3BA 3G5CA 4GQLA 2QPJA 1K7GA 3N2VA 3Q2HA 3DTEA 1UEAA 5JMYA 4GWNA 1KUFA 3TSKA 1JAQA 4H49A 1XUDA 4CTHA 1GE6A 1PWVA 1KBCA 1OM6A 1USNA 3ZVSA 1G4KA 2W13A 1QIBA 4H1QA 2D1OA 2OXZA 1BZSA 1Q3AA 2RJPA 1RM8A 3EWJA 3TT4A 1G9KA 1UMSA 1ZVXA 3HY7A 1R54A 1GO7P 2TCLA 1YQYA 3LUNA 2X3CA 1AYKA 1KUIA 3NX7A 1BKCE 4GWMA 4WF6A 1PWWA 4GR0A 1QJJA 1OS2A 5BOTA 3KEJA 4FVLA 3E8RA 2RJQA 4AUOA 2OW9A 5L79A 4I03A 3DL1A 1YP1A 1BSWA 3HY9A 1WNIA 5CXAA 4AIGA 1JAPA 1XAXA 4H84A 1BKCI 1OMJA 1YOUA 2DW2A 1TVIA 1JIWP 3WV1A 3KMEA 3DSLA 3O2XA 1L6JA 3KECA 3BA0A 3LIKA 2OW0A 1PWUA 4IUWA 1ZXCA 5BPAA 3LGPA 4JIJA 4AXQA 3I7IA 1IAGA 2JT6A 1AF0A 2W12A 1KUHA 2E2DA 3DPFA 1IADA 3P24A 2W0DA 3EDZA 2O36A 1HOVA 3EHXA 1DMTA 2Y6DA 2OW2A 4ILWD 1GO8P 1IACA 3LJZA 1SLMA 2DW1A 1R55A 2OVXA 4GF1A 2JIHA 1GE5A 3HBUP 1HV5A 1JJ9A 5I4OA 3HDBA 4L7AA 4Q1LA 1BM6A 3K7LA 5D2BA 2V4BA 1J7NA 3F19A 2YB9A 2POJA 3CKIA 4H2EA 4XM6A 3V96B 3TS4A 3LEAA 1ND1A 1BKCA 1RMZA 1ZP5A 5CZMA 2W15A 3KHIA 1ROSA 4WKIA 1XURA 2MLSA 5H8XA 4L6TA 3ELMA 456CA 2MZEA 3WV2A 3MA2A 1H71P 4EFSA 3K7NA 1SMPA 4PKUA 3B92A 3LKAA 3KMCA 4PKTA 5D3CA 3EDGA 4H3XA 1B8YA 4GR3A 1MMRA 1G49A 4XCTA 4G0DA 4PKSA 1JK3A 3DNGA 2AYKA 1ZS0A 4FU4A 5D1TA 1HFCA 3HBVP 2OZRA 4FXYP 4ZR5A 3LILA 4L19A 1PWPA 2OXUA 2PJTA 5I12A 1ZTQA 3F16A 1CQRA 3RTTA 1Z3JA 1HFSA 4R3VA 4J4MA 1OM7A 1SRPA 3LK8A 2JT5A 4PKQA 3F17A 3KRYA 4A7BA 2J0TA 3USNA 1QJIA 4L63A 1BUDA 2L0RA 4HX3A 3VTGA 2N8RA 2X3AA 4JA1A 5I43A 2W14A 5D1UA 3HB2P 1O0QA 1CIZA 1BQOA 1MNCA 4FXQA 4H76A 1OZ9A 1QIAA 3L0TA 1I1IP 4XM7A 2CKIA 3RTSA 1KAPP 1SATA 2WO9A 4PKWA 1OO9A 2SRTA 4WKEA 3EDIA 2CLTA 3B8ZA
chains in the Genus database with same CATH topology
1ATLA 2USNA 3LE9A 1MMBA 1D5JA 4XM8A 2E3XA 2YIGA 1K7QA 2WO8A 4IN9A 1HY7A 5I3MA 4PKRA 1EB6A 2Z2DA 5B5OA 5CUHA 4H30A 4ON1A 4WK7A 1D8FA 2JSDA 3LUMA 1IAAA 3DPEA 1C7KA 1S4BP 1GXDA 3AIGA 3EDHA 4DD8A 1XFXA 2Y6CA 4PKVA 1CXVA 2DW0A 1XFVA 2DDYA 5BOYA 1ZXVA 3LJGA 4JPAA 3P1VA 3HDAP 1CGFA 1PWQA 2WOAA 2ERPA 2EROA 1HTDA 2J83A 5B5PA 1CAQA 2FV5A 1C8TA 1Y0VA 3EHYA 3B2ZA 4XBHA 1CGLA 1SLNA 1Y93A 1AKLA 1D7XA 2OVZA 2MZHA 1R1IA 1Y8JA 2YUFA 2OW1A 1QUAA 3DTKA 4A3WA 830CA 2MZIA 3I7GA 1YCMA 966CA 1SU3A 4G9LA 5D1SA 1A86A 1R1JA 1GKCA 3LQ0A 1JANA 1MMQA 1O0TA 2A8HA 1C3IA 1XFUA 2I47A 2OY2A 3LJTA 3DTIA 3F1AA 1D8MA 4QKZA 1JAOA 1G12A 3G42A 2K2GA 2X7MA 3GBOA 3U1RA 1IABA 1UMTA 4DPEA 3HYGA 3ZUKA 3VI1A 1DTHA 1XFWA 2D1NA 5I2ZA 5L7FA 2OXWA 3KEKA 4H82A 3F15A 1I73A 2XS3A 2KRJA 3N2UA 1CK7A 2DDFA 1KUKA 4HMAA 1A85A 2JNPA 4AYKA 3AYKA 3ZXHA 1BUVM 1UTTA 3OHOA 3O64A 1G05A 2XS4A 1KUGA 4GR8A 3F18A 1FBLA 1IAEA 4I35A 3SHIA 3KWVC 5D7WA 2O3EA 2ERQA 1OS9A 4WZVA 1XUCA 1OM8A 5LABA 2FV9A 2MLRA 1QICA 2OI0A 4DF9A 1XFYA 2AIGP 4JQGA 3OHLA 1EAKA 2HU6A 4DV8A 4JP4A 4GUYA 3WV3A 3UVCA 1R1HA 1EUBA 3Q2GA 1ASTA 1B3DA 3AYUA 3LQBA 4IJOA 1JIZA 1K7IA 1CGEA 1FLSA 5I0LA 1XFZA 1MMPA 2OY4A 3LIRA 3DWBA 3L0VA 2K9CA 1GE7A 1I76A 1FM1A 1BQQM 1JH1A 1BIWA 1UTZA 3TVCA 1GKDA 1JKYA 3LMCA 2X3BA 3G5CA 4GQLA 2QPJA 1K7GA 3N2VA 3Q2HA 3DTEA 1UEAA 5JMYA 4GWNA 1KUFA 3TSKA 1JAQA 4H49A 1XUDA 4CTHA 1GE6A 1PWVA 1KBCA 1OM6A 1USNA 3ZVSA 1G4KA 2W13A 1QIBA 4H1QA 2D1OA 2OXZA 1BZSA 1Q3AA 2RJPA 1RM8A 3EWJA 3TT4A 1G9KA 1UMSA 1ZVXA 3HY7A 1R54A 1GO7P 2TCLA 1YQYA 3LUNA 2X3CA 1AYKA 1KUIA 3NX7A 1BKCE 4GWMA 4WF6A 1PWWA 4GR0A 1QJJA 1OS2A 5BOTA 3KEJA 4FVLA 3E8RA 2RJQA 4AUOA 2OW9A 5L79A 4I03A 3DL1A 1YP1A 1BSWA 3HY9A 1WNIA 5CXAA 4AIGA 1JAPA 4H84A 1BKCI 1OMJA 1YOUA 2DW2A 1JIWP 3WV1A 3KMEA 3DSLA 3O2XA 1L6JA 3KECA 3BA0A 3LIKA 2OW0A 1PWUA 4IUWA 1ZXCA 5BPAA 3LGPA 4JIJA 4AXQA 3I7IA 1IAGA 2JT6A 1AF0A 2W12A 1KUHA 2E2DA 3DPFA 1IADA 3P24A 2W0DA 3EDZA 2O36A 1HOVA 3EHXA 1DMTA 2Y6DA 2OW2A 4ILWD 1GO8P 1IACA 3LJZA 1SLMA 2DW1A 1R55A 2OVXA 4GF1A 2JIHA 1GE5A 3HBUP 1HV5A 1JJ9A 5I4OA 3HDBA 4L7AA 4Q1LA 1BM6A 3K7LA 5D2BA 2V4BA 1J7NA 3F19A 2YB9A 2POJA 3CKIA 4H2EA 4XM6A 3V96B 3TS4A 3LEAA 1ND1A 1BKCA 1RMZA 1ZP5A 5CZMA 2W15A 3KHIA 1ROSA 4WKIA 1XURA 2MLSA 5H8XA 4L6TA 3ELMA 456CA 2MZEA 3WV2A 3MA2A 1H71P 4EFSA 3K7NA 1SMPA 4PKUA 3B92A 3LKAA 3KMCA 4PKTA 5D3CA 3EDGA 4H3XA 1B8YA 4GR3A 1MMRA 1G49A 4XCTA 4G0DA 4PKSA 1JK3A 3DNGA 2AYKA 1ZS0A 4FU4A 5D1TA 1HFCA 3HBVP 2OZRA 4FXYP 4ZR5A 3LILA 4L19A 1PWPA 2OXUA 2PJTA 5I12A 1ZTQA 3F16A 1CQRA 3RTTA 1Z3JA 1HFSA 4R3VA 4J4MA 1OM7A 1SRPA 3LK8A 2JT5A 4PKQA 3F17A 3KRYA 4A7BA 2J0TA 3USNA 1QJIA 4L63A 1BUDA 2L0RA 4HX3A 3VTGA 2N8RA 2X3AA 4JA1A 5I43A 2W14A 5D1UA 3HB2P 1O0QA 1CIZA 1BQOA 1MNCA 4FXQA 4H76A 1QIAA 3L0TA 1I1IP 4XM7A 2CKIA 3RTSA 1KAPP 1SATA 2WO9A 4PKWA 1OO9A 2SRTA 4WKEA 3EDIA 2CLTA 3B8ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ATL A;  2USN A;  3LE9 A;  1MMB A;  1D5J A;  4XM8 A;  2E3X A;  2YIG A;  1K7Q A;  2WO8 A;  4IN9 A;  1HY7 A;  5I3M A;  4PKR A;  1EB6 A;  2Z2D A;  5B5O A;  5CUH A;  4H30 A;  4ON1 A;  4WK7 A;  1D8F A;  2JSD A;  3LUM A;  1IAA A;  3DPE A;  1C7K A;  1S4B P;  1GXD A;  3AIG A;  3EDH A;  4DD8 A;  1XFX A;  2Y6C A;  4PKV A;  1CXV A;  2DW0 A;  1XFV A;  2DDY A;  5BOY A;  1ZXV A;  3LJG A;  4JPA A;  3P1V A;  3HDA P;  1CGF A;  1PWQ A;  2WOA A;  2ERP A;  2ERO A;  1HTD A;  2J83 A;  5B5P A;  1CAQ A;  2FV5 A;  1C8T A;  1Y0V A;  3EHY A;  3B2Z A;  4XBH A;  1CGL A;  1SLN A;  1Y93 A;  1AKL A;  1D7X A;  2OVZ A;  2MZH A;  1R1I A;  1Y8J A;  2OW1 A;  1QUA A;  4A3W A;  830C A;  2MZI A;  3I7G A;  1YCM A;  966C A;  1SU3 A;  4G9L A;  5D1S A;  1A86 A;  1R1J A;  1GKC A;  3LQ0 A;  1JAN A;  1MMQ A;  1O0T A;  2A8H A;  1C3I A;  1XFU A;  2I47 A;  2OY2 A;  3LJT A;  3F1A A;  1D8M A;  4QKZ A;  1JAO A;  1G12 A;  3G42 A;  2K2G A;  2X7M A;  3GBO A;  3U1R A;  1IAB A;  1UMT A;  4DPE A;  3HYG A;  3ZUK A;  3VI1 A;  1DTH A;  1XFW A;  2D1N A;  5I2Z A;  5L7F A;  2OXW A;  3KEK A;  4H82 A;  3F15 A;  1I73 A;  2XS3 A;  2KRJ A;  3N2U A;  1CK7 A;  2DDF A;  1KUK A;  4HMA A;  1A85 A;  2JNP A;  4AYK A;  3AYK A;  3ZXH A;  1BUV M;  1UTT A;  3OHO A;  3O64 A;  1G05 A;  2XS4 A;  1KUG A;  4GR8 A;  3F18 A;  1FBL A;  1IAE A;  4I35 A;  3SHI A;  3KWV C;  5D7W A;  2O3E A;  2ERQ A;  1OS9 A;  4WZV A;  1XUC A;  1OM8 A;  5LAB A;  2FV9 A;  2MLR A;  1QIC A;  2OI0 A;  4DF9 A;  1XFY A;  2AIG P;  4JQG A;  3OHL A;  1EAK A;  2HU6 A;  4DV8 A;  4JP4 A;  4GUY A;  3WV3 A;  3UVC A;  1R1H A;  1EUB A;  3Q2G A;  1AST A;  1B3D A;  3AYU A;  3LQB A;  4IJO A;  1JIZ A;  1K7I A;  1CGE A;  1FLS A;  5I0L A;  1XFZ A;  1MMP A;  2OY4 A;  3LIR A;  3DWB A;  3L0V A;  2K9C A;  1GE7 A;  1I76 A;  1FM1 A;  1BQQ M;  1JH1 A;  1BIW A;  1UTZ A;  3TVC A;  1GKD A;  1JKY A;  3LMC A;  2X3B A;  3G5C A;  4GQL A;  2QPJ A;  1K7G A;  3N2V A;  3Q2H A;  1UEA A;  5JMY A;  4GWN A;  1KUF A;  3TSK A;  1JAQ A;  4H49 A;  1XUD A;  4CTH A;  1GE6 A;  1PWV A;  1KBC A;  1OM6 A;  1USN A;  3ZVS A;  1G4K A;  2W13 A;  1QIB A;  4H1Q A;  2D1O A;  2OXZ A;  1BZS A;  1Q3A A;  2RJP A;  1RM8 A;  3EWJ A;  3TT4 A;  1G9K A;  1UMS A;  1ZVX A;  3HY7 A;  1R54 A;  1GO7 P;  2TCL A;  1YQY A;  3LUN A;  2X3C A;  1AYK A;  1KUI A;  3NX7 A;  1BKC E;  4GWM A;  4WF6 A;  1PWW A;  4GR0 A;  1QJJ A;  1OS2 A;  5BOT A;  3KEJ A;  4FVL A;  3E8R A;  2RJQ A;  4AUO A;  2OW9 A;  5L79 A;  4I03 A;  3DL1 A;  1YP1 A;  1BSW A;  3HY9 A;  1WNI A;  5CXA A;  4AIG A;  1JAP A;  4H84 A;  1BKC I;  1OMJ A;  1YOU A;  2DW2 A;  1JIW P;  3WV1 A;  3KME A;  3DSL A;  3O2X A;  1L6J A;  3KEC A;  3BA0 A;  3LIK A;  2OW0 A;  1PWU A;  4IUW A;  1ZXC A;  5BPA A;  3LGP A;  4JIJ A;  4AXQ A;  3I7I A;  1IAG A;  2JT6 A;  1AF0 A;  2W12 A;  1KUH A;  2E2D A;  3DPF A;  1IAD A;  3P24 A;  2W0D A;  3EDZ A;  2O36 A;  1HOV A;  3EHX A;  1DMT A;  2Y6D A;  2OW2 A;  4ILW D;  1GO8 P;  1IAC A;  3LJZ A;  1SLM A;  2DW1 A;  1R55 A;  2OVX A;  4GF1 A;  2JIH A;  1GE5 A;  3HBU P;  1HV5 A;  1JJ9 A;  5I4O A;  3HDB A;  4Q1L A;  1BM6 A;  3K7L A;  5D2B A;  2V4B A;  1J7N A;  3F19 A;  2YB9 A;  2POJ A;  3CKI A;  4H2E A;  4XM6 A;  3V96 B;  3TS4 A;  3LEA A;  1ND1 A;  1BKC A;  1RMZ A;  1ZP5 A;  5CZM A;  2W15 A;  3KHI A;  1ROS A;  4WKI A;  1XUR A;  2MLS A;  5H8X A;  4L6T A;  3ELM A;  456C A;  2MZE A;  3WV2 A;  3MA2 A;  1H71 P;  4EFS A;  3K7N A;  1SMP A;  4PKU A;  3B92 A;  3LKA A;  3KMC A;  4PKT A;  5D3C A;  3EDG A;  4H3X A;  1B8Y A;  4GR3 A;  1MMR A;  1G49 A;  4XCT A;  4G0D A;  4PKS A;  1JK3 A;  3DNG A;  2AYK A;  1ZS0 A;  4FU4 A;  5D1T A;  1HFC A;  3HBV P;  2OZR A;  4FXY P;  4ZR5 A;  3LIL A;  4L19 A;  1PWP A;  2OXU A;  2PJT A;  5I12 A;  1ZTQ A;  3F16 A;  1CQR A;  3RTT A;  1Z3J A;  1HFS A;  4R3V A;  4J4M A;  1OM7 A;  1SRP A;  3LK8 A;  2JT5 A;  4PKQ A;  3F17 A;  3KRY A;  4A7B A;  2J0T A;  3USN A;  1QJI A;  4L63 A;  1BUD A;  2L0R A;  4HX3 A;  3VTG A;  2N8R A;  2X3A A;  4JA1 A;  5I43 A;  2W14 A;  5D1U A;  3HB2 P;  1O0Q A;  1CIZ A;  1BQO A;  1MNC A;  4FXQ A;  4H76 A;  1QIA A;  3L0T A;  1I1I P;  4XM7 A;  2CKI A;  3RTS A;  1KAP P;  1SAT A;  2WO9 A;  4PKW A;  1OO9 A;  2SRT A;  4WKE A;  3EDI A;  2CLT A;  3B8Z A; 
#chains in the Genus database with same CATH topology
 1ATL A;  2USN A;  3LE9 A;  1MMB A;  1D5J A;  4XM8 A;  2E3X A;  2YIG A;  1K7Q A;  2WO8 A;  4IN9 A;  1HY7 A;  5I3M A;  4PKR A;  1EB6 A;  2Z2D A;  5B5O A;  5CUH A;  4H30 A;  4ON1 A;  4WK7 A;  1D8F A;  2JSD A;  3LUM A;  1IAA A;  3DPE A;  1C7K A;  1S4B P;  1GXD A;  3AIG A;  3EDH A;  4DD8 A;  1XFX A;  2Y6C A;  4PKV A;  1CXV A;  2DW0 A;  1XFV A;  2DDY A;  5BOY A;  1ZXV A;  3LJG A;  4JPA A;  3P1V A;  3HDA P;  1CGF A;  1PWQ A;  2WOA A;  2ERP A;  2ERO A;  1HTD A;  2J83 A;  5B5P A;  1CAQ A;  2FV5 A;  1C8T A;  1Y0V A;  3EHY A;  3B2Z A;  4XBH A;  1CGL A;  1SLN A;  1Y93 A;  1AKL A;  1D7X A;  2OVZ A;  2MZH A;  1R1I A;  1Y8J A;  2YUF A;  2OW1 A;  1QUA A;  3DTK A;  4A3W A;  830C A;  2MZI A;  3I7G A;  1YCM A;  966C A;  1SU3 A;  4G9L A;  5D1S A;  1A86 A;  1R1J A;  1GKC A;  3LQ0 A;  1JAN A;  1MMQ A;  1O0T A;  2A8H A;  1C3I A;  1XM5 A;  1XFU A;  2I47 A;  2OY2 A;  3LJT A;  3DTI A;  3F1A A;  1D8M A;  4QKZ A;  1JAO A;  1G12 A;  3G42 A;  2K2G A;  2X7M A;  3GBO A;  3U1R A;  1IAB A;  1UMT A;  4DPE A;  3HYG A;  3ZUK A;  3VI1 A;  1DTH A;  1XFW A;  2D1N A;  5I2Z A;  5L7F A;  2OXW A;  3KEK A;  4H82 A;  3F15 A;  1I73 A;  2XS3 A;  2KRJ A;  3N2U A;  1CK7 A;  2DDF A;  1KUK A;  4HMA A;  1A85 A;  2JNP A;  4AYK A;  3AYK A;  3ZXH A;  1BUV M;  1UTT A;  3OHO A;  3O64 A;  1G05 A;  2XS4 A;  1KUG A;  4GR8 A;  3F18 A;  1FBL A;  1IAE A;  4I35 A;  3SHI A;  3KWV C;  5D7W A;  2O3E A;  2ERQ A;  1OS9 A;  4WZV A;  1XUC A;  1OM8 A;  5LAB A;  2FV9 A;  2MLR A;  1QIC A;  2OI0 A;  4DF9 A;  1XFY A;  2AIG P;  4JQG A;  3OHL A;  1EAK A;  2HU6 A;  4DV8 A;  4JP4 A;  4GUY A;  3WV3 A;  3UVC A;  1R1H A;  1EUB A;  3Q2G A;  1AST A;  1B3D A;  3AYU A;  3LQB A;  4IJO A;  1JIZ A;  1K7I A;  1CGE A;  1FLS A;  5I0L A;  1XFZ A;  1MMP A;  2OY4 A;  3LIR A;  3DWB A;  3L0V A;  2K9C A;  1GE7 A;  1I76 A;  1FM1 A;  1BQQ M;  1JH1 A;  1BIW A;  1UTZ A;  3TVC A;  1GKD A;  1JKY A;  3LMC A;  2X3B A;  3G5C A;  4GQL A;  2QPJ A;  1K7G A;  3N2V A;  3Q2H A;  3DTE A;  1UEA A;  5JMY A;  4GWN A;  1KUF A;  3TSK A;  1JAQ A;  4H49 A;  1XUD A;  4CTH A;  1GE6 A;  1PWV A;  1KBC A;  1OM6 A;  1USN A;  3ZVS A;  1G4K A;  2W13 A;  1QIB A;  4H1Q A;  2D1O A;  2OXZ A;  1BZS A;  1Q3A A;  2RJP A;  1RM8 A;  3EWJ A;  3TT4 A;  1G9K A;  1UMS A;  1ZVX A;  3HY7 A;  1R54 A;  1GO7 P;  2TCL A;  1YQY A;  3LUN A;  2X3C A;  1AYK A;  1KUI A;  3NX7 A;  1BKC E;  4GWM A;  4WF6 A;  1PWW A;  4GR0 A;  1QJJ A;  1OS2 A;  5BOT A;  3KEJ A;  4FVL A;  3E8R A;  2RJQ A;  4AUO A;  2OW9 A;  5L79 A;  4I03 A;  3DL1 A;  1YP1 A;  1BSW A;  3HY9 A;  1WNI A;  5CXA A;  4AIG A;  1JAP A;  1XAX A;  4H84 A;  1BKC I;  1OMJ A;  1YOU A;  2DW2 A;  1TVI A;  1JIW P;  3WV1 A;  3KME A;  3DSL A;  3O2X A;  1L6J A;  3KEC A;  3BA0 A;  3LIK A;  2OW0 A;  1PWU A;  4IUW A;  1ZXC A;  5BPA A;  3LGP A;  4JIJ A;  4AXQ A;  3I7I A;  1IAG A;  2JT6 A;  1AF0 A;  2W12 A;  1KUH A;  2E2D A;  3DPF A;  1IAD A;  3P24 A;  2W0D A;  3EDZ A;  2O36 A;  1HOV A;  3EHX A;  1DMT A;  2Y6D A;  2OW2 A;  4ILW D;  1GO8 P;  1IAC A;  3LJZ A;  1SLM A;  2DW1 A;  1R55 A;  2OVX A;  4GF1 A;  2JIH A;  1GE5 A;  3HBU P;  1HV5 A;  1JJ9 A;  5I4O A;  3HDB A;  4L7A A;  4Q1L A;  1BM6 A;  3K7L A;  5D2B A;  2V4B A;  1J7N A;  3F19 A;  2YB9 A;  2POJ A;  3CKI A;  4H2E A;  4XM6 A;  3V96 B;  3TS4 A;  3LEA A;  1ND1 A;  1BKC A;  1RMZ A;  1ZP5 A;  5CZM A;  2W15 A;  3KHI A;  1ROS A;  4WKI A;  1XUR A;  2MLS A;  5H8X A;  4L6T A;  3ELM A;  456C A;  2MZE A;  3WV2 A;  3MA2 A;  1H71 P;  4EFS A;  3K7N A;  1SMP A;  4PKU A;  3B92 A;  3LKA A;  3KMC A;  4PKT A;  5D3C A;  3EDG A;  4H3X A;  1B8Y A;  4GR3 A;  1MMR A;  1G49 A;  4XCT A;  4G0D A;  4PKS A;  1JK3 A;  3DNG A;  2AYK A;  1ZS0 A;  4FU4 A;  5D1T A;  1HFC A;  3HBV P;  2OZR A;  4FXY P;  4ZR5 A;  3LIL A;  4L19 A;  1PWP A;  2OXU A;  2PJT A;  5I12 A;  1ZTQ A;  3F16 A;  1CQR A;  3RTT A;  1Z3J A;  1HFS A;  4R3V A;  4J4M A;  1OM7 A;  1SRP A;  3LK8 A;  2JT5 A;  4PKQ A;  3F17 A;  3KRY A;  4A7B A;  2J0T A;  3USN A;  1QJI A;  4L63 A;  1BUD A;  2L0R A;  4HX3 A;  3VTG A;  2N8R A;  2X3A A;  4JA1 A;  5I43 A;  2W14 A;  5D1U A;  3HB2 P;  1O0Q A;  1CIZ A;  1BQO A;  1MNC A;  4FXQ A;  4H76 A;  1OZ9 A;  1QIA A;  3L0T A;  1I1I P;  4XM7 A;  2CKI A;  3RTS A;  1KAP P;  1SAT A;  2WO9 A;  4PKW A;  1OO9 A;  2SRT A;  4WKE A;  3EDI A;  2CLT A;  3B8Z A; 
#chains in the Genus database with same CATH homology
 1ATL A;  2USN A;  3LE9 A;  1MMB A;  1D5J A;  4XM8 A;  2E3X A;  2YIG A;  1K7Q A;  2WO8 A;  4IN9 A;  1HY7 A;  5I3M A;  4PKR A;  1EB6 A;  2Z2D A;  5B5O A;  5CUH A;  4H30 A;  4ON1 A;  4WK7 A;  1D8F A;  2JSD A;  3LUM A;  1IAA A;  3DPE A;  1C7K A;  1S4B P;  1GXD A;  3AIG A;  3EDH A;  4DD8 A;  1XFX A;  2Y6C A;  4PKV A;  1CXV A;  2DW0 A;  1XFV A;  2DDY A;  5BOY A;  1ZXV A;  3LJG A;  4JPA A;  3P1V A;  3HDA P;  1CGF A;  1PWQ A;  2WOA A;  2ERP A;  2ERO A;  1HTD A;  2J83 A;  5B5P A;  1CAQ A;  2FV5 A;  1C8T A;  1Y0V A;  3EHY A;  3B2Z A;  4XBH A;  1CGL A;  1SLN A;  1Y93 A;  1AKL A;  1D7X A;  2OVZ A;  2MZH A;  1R1I A;  1Y8J A;  2YUF A;  2OW1 A;  1QUA A;  3DTK A;  4A3W A;  830C A;  2MZI A;  3I7G A;  1YCM A;  966C A;  1SU3 A;  4G9L A;  5D1S A;  1A86 A;  1R1J A;  1GKC A;  3LQ0 A;  1JAN A;  1MMQ A;  1O0T A;  2A8H A;  1C3I A;  1XFU A;  2I47 A;  2OY2 A;  3LJT A;  3DTI A;  3F1A A;  1D8M A;  4QKZ A;  1JAO A;  1G12 A;  3G42 A;  2K2G A;  2X7M A;  3GBO A;  3U1R A;  1IAB A;  1UMT A;  4DPE A;  3HYG A;  3ZUK A;  3VI1 A;  1DTH A;  1XFW A;  2D1N A;  5I2Z A;  5L7F A;  2OXW A;  3KEK A;  4H82 A;  3F15 A;  1I73 A;  2XS3 A;  2KRJ A;  3N2U A;  1CK7 A;  2DDF A;  1KUK A;  4HMA A;  1A85 A;  2JNP A;  4AYK A;  3AYK A;  3ZXH A;  1BUV M;  1UTT A;  3OHO A;  3O64 A;  1G05 A;  2XS4 A;  1KUG A;  4GR8 A;  3F18 A;  1FBL A;  1IAE A;  4I35 A;  3SHI A;  3KWV C;  5D7W A;  2O3E A;  2ERQ A;  1OS9 A;  4WZV A;  1XUC A;  1OM8 A;  5LAB A;  2FV9 A;  2MLR A;  1QIC A;  2OI0 A;  4DF9 A;  1XFY A;  2AIG P;  4JQG A;  3OHL A;  1EAK A;  2HU6 A;  4DV8 A;  4JP4 A;  4GUY A;  3WV3 A;  3UVC A;  1R1H A;  1EUB A;  3Q2G A;  1AST A;  1B3D A;  3AYU A;  3LQB A;  4IJO A;  1JIZ A;  1K7I A;  1CGE A;  1FLS A;  5I0L A;  1XFZ A;  1MMP A;  2OY4 A;  3LIR A;  3DWB A;  3L0V A;  2K9C A;  1GE7 A;  1I76 A;  1FM1 A;  1BQQ M;  1JH1 A;  1BIW A;  1UTZ A;  3TVC A;  1GKD A;  1JKY A;  3LMC A;  2X3B A;  3G5C A;  4GQL A;  2QPJ A;  1K7G A;  3N2V A;  3Q2H A;  3DTE A;  1UEA A;  5JMY A;  4GWN A;  1KUF A;  3TSK A;  1JAQ A;  4H49 A;  1XUD A;  4CTH A;  1GE6 A;  1PWV A;  1KBC A;  1OM6 A;  1USN A;  3ZVS A;  1G4K A;  2W13 A;  1QIB A;  4H1Q A;  2D1O A;  2OXZ A;  1BZS A;  1Q3A A;  2RJP A;  1RM8 A;  3EWJ A;  3TT4 A;  1G9K A;  1UMS A;  1ZVX A;  3HY7 A;  1R54 A;  1GO7 P;  2TCL A;  1YQY A;  3LUN A;  2X3C A;  1AYK A;  1KUI A;  3NX7 A;  1BKC E;  4GWM A;  4WF6 A;  1PWW A;  4GR0 A;  1QJJ A;  1OS2 A;  5BOT A;  3KEJ A;  4FVL A;  3E8R A;  2RJQ A;  4AUO A;  2OW9 A;  5L79 A;  4I03 A;  3DL1 A;  1YP1 A;  1BSW A;  3HY9 A;  1WNI A;  5CXA A;  4AIG A;  1JAP A;  4H84 A;  1BKC I;  1OMJ A;  1YOU A;  2DW2 A;  1JIW P;  3WV1 A;  3KME A;  3DSL A;  3O2X A;  1L6J A;  3KEC A;  3BA0 A;  3LIK A;  2OW0 A;  1PWU A;  4IUW A;  1ZXC A;  5BPA A;  3LGP A;  4JIJ A;  4AXQ A;  3I7I A;  1IAG A;  2JT6 A;  1AF0 A;  2W12 A;  1KUH A;  2E2D A;  3DPF A;  1IAD A;  3P24 A;  2W0D A;  3EDZ A;  2O36 A;  1HOV A;  3EHX A;  1DMT A;  2Y6D A;  2OW2 A;  4ILW D;  1GO8 P;  1IAC A;  3LJZ A;  1SLM A;  2DW1 A;  1R55 A;  2OVX A;  4GF1 A;  2JIH A;  1GE5 A;  3HBU P;  1HV5 A;  1JJ9 A;  5I4O A;  3HDB A;  4L7A A;  4Q1L A;  1BM6 A;  3K7L A;  5D2B A;  2V4B A;  1J7N A;  3F19 A;  2YB9 A;  2POJ A;  3CKI A;  4H2E A;  4XM6 A;  3V96 B;  3TS4 A;  3LEA A;  1ND1 A;  1BKC A;  1RMZ A;  1ZP5 A;  5CZM A;  2W15 A;  3KHI A;  1ROS A;  4WKI A;  1XUR A;  2MLS A;  5H8X A;  4L6T A;  3ELM A;  456C A;  2MZE A;  3WV2 A;  3MA2 A;  1H71 P;  4EFS A;  3K7N A;  1SMP A;  4PKU A;  3B92 A;  3LKA A;  3KMC A;  4PKT A;  5D3C A;  3EDG A;  4H3X A;  1B8Y A;  4GR3 A;  1MMR A;  1G49 A;  4XCT A;  4G0D A;  4PKS A;  1JK3 A;  3DNG A;  2AYK A;  1ZS0 A;  4FU4 A;  5D1T A;  1HFC A;  3HBV P;  2OZR A;  4FXY P;  4ZR5 A;  3LIL A;  4L19 A;  1PWP A;  2OXU A;  2PJT A;  5I12 A;  1ZTQ A;  3F16 A;  1CQR A;  3RTT A;  1Z3J A;  1HFS A;  4R3V A;  4J4M A;  1OM7 A;  1SRP A;  3LK8 A;  2JT5 A;  4PKQ A;  3F17 A;  3KRY A;  4A7B A;  2J0T A;  3USN A;  1QJI A;  4L63 A;  1BUD A;  2L0R A;  4HX3 A;  3VTG A;  2N8R A;  2X3A A;  4JA1 A;  5I43 A;  2W14 A;  5D1U A;  3HB2 P;  1O0Q A;  1CIZ A;  1BQO A;  1MNC A;  4FXQ A;  4H76 A;  1QIA A;  3L0T A;  1I1I P;  4XM7 A;  2CKI A;  3RTS A;  1KAP P;  1SAT A;  2WO9 A;  4PKW A;  1OO9 A;  2SRT A;  4WKE A;  3EDI A;  2CLT A;  3B8Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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