3LKAA

Catalytic domain of human mmp-12 complexed with hydroxamic acid and paramethoxy-sulfonyl amide
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Entropic contribution to the linking coefficient in fragment based drug design: a case study.
pubmed doi rcsb
molecule keywords Macrophage metalloelastase
molecule tags Hydrolase
source organism Homo sapiens
total genus 45
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3lkaA00
3KWVC 1IACA 1UTZA 2DDYA 5LABA 1MMPA 1Y93A 1YOUA 4PKTA 4R3VA 3LILA 1SATA 5BOTA 1UMTA 1L6JA 3EDGA 3OHOA 5L79A 3WV1A 3LK8A 2I47A 4I35A 1YP1A 1QJIA 1YCMA 1JANA 1IAGA 1FBLA 1G05A 3DPFA 3N2VA 2OXWA 1OS2A 5B5PA 1HOVA 4FXQA 1OM8A 4ON1A 5D1UA 5D1TA 2O3EA 4JP4A 5D1SA 3ZXHA 3DL1A 2AIGP 1CAQA 2QPJA 4GWNA 4PKSA 1BKCI 4WKEA 1K7QA 1ZXCA 3EDIA 3LE9A 2JNPA 4IN9A 3P1VA 2ERPA 4WKIA 3VI1A 3HDBA 2J0TA 1AYKA 1BUVM 3GBOA 3N2UA 4AYKA 3F18A 5I2ZA 1ZTQA 4IUWA 2DW2A 1PWUA 1KUFA 3KEJA 4L6TA 4ILWD 4L63A 4PKVA 1D7XA 4GR0A 4AXQA 3DNGA 4ZR5A 3OHLA 4HMAA 1ATLA 2ERQA 1GKCA 2RJPA 5CUHA 5I12A 4H3XA 2SRTA 3BA0A 1A86A 4GUYA 1Y8JA 2D1OA 2OZRA 1ZXVA 1B3DA 1UMSA 4CTHA 2JT6A 2OW2A 1G4KA 5D7WA 1HTDA 3LEAA 2WOAA 1GE6A 2OXUA 1KUHA 3HB2P 966CA 1HFSA 2MZIA 3O64A 2D1NA 1BKCE 3K7NA 3AYKA 2DDFA 1QIBA 3TVCA 1CGFA 2A8HA 2J83A 4HX3A 3TSKA 5D3CA 3LJTA 2MLSA 1MMRA 3G5CA 1AKLA 2POJA 2W15A 1C7KA 1FLSA 2YIGA 5BPAA 4GQLA 2MZHA 1PWWA 1MNCA 4L19A 2W13A 3UVCA 3B2ZA 4GR3A 1GO7P 1KAPP 1BM6A 1PWVA 2XS3A 4DPEA 3Q2HA 5B5OA 2JSDA 4XCTA 3LJGA 2K9CA 1Z3JA 4PKQA 2DW0A 1G12A 5JMYA 3LJZA 3G42A 3LIRA 1OM6A 1JK3A 456CA 2DW1A 1DMTA 5D2BA 5H8XA 5I3MA 3I7IA 4EFSA 1ZVXA 1ND1A 4XM7A 1RMZA 2OY2A 1CGLA 4WF6A 2WO9A 1JKYA 1O0QA 3ELMA 3KMCA 1CIZA 4H30A 3RTSA 3AIGA 2W14A 1GE5A 1SLMA 3F19A 3B8ZA 1MMBA 1XFZA 4WZVA 2X3AA 1IAAA 1G9KA 3KECA 3LQBA 1R1JA 1EB6A 2MZEA 4H2EA 4AUOA 1R54A 4QKZA 5CXAA 3KHIA 1XUDA 4H84A 3E8RA 1C3IA 4XM8A 1BIWA 2OY4A 3MA2A 3P24A 2E2DA 2OW1A 4PKRA 3VTGA 3NX7A 2MLRA 1GXDA 1QIAA 4PKUA 4WK7A 1C8TA 2OVZA 2K2GA 3L0VA 2YB9A 4J4MA 1KUKA 3LMCA 1IADA 4GWMA 1MMQA 1A85A 1B8YA 1K7GA 1K7IA 1YQYA 3EWJA 4JQGA 2HU6A 1JH1A 4FVLA 1H71P 1D5JA 1R1HA 2FV9A 3LUNA 5I4OA 1Q3AA 4H82A 3V96B 2V4BA 1CQRA 3L0TA 1XFXA 2JIHA 3B92A 1KUGA 1JAPA 4DD8A 2AYKA 2X3BA 1I1IP 1D8MA 1UEAA 2RJQA 2XS4A 4A3WA 3I7GA 2N8RA 3HYGA 1XFYA 3LIKA 4DV8A 4Q1LA 3HBVP 1EUBA 5I0LA 4XBHA 4GF1A 4FXYP 1XFVA 2OI0A 5CZMA 3CKIA 3EDHA 1GE7A 1XURA 1BQOA 1PWQA 4IJOA 1OO9A 1BZSA 1BKCA 1BSWA 2W12A 1DTHA 1FM1A 3EHYA 2O36A 1J7NA 1UTTA 1ZP5A 3AYUA 2Z2DA 3RTTA 2W0DA 3KMEA 4JPAA 1CK7A 3F15A 4GR8A 1EAKA 1CGEA 1SU3A 1XUCA 4PKWA 2L0RA 1QJJA 5I43A 1SLNA 3SHIA 1JIZA 2OXZA 4DF9A 1IABA 3DPEA 2X7MA 3HDAP 3F16A 3EDZA 1KBCA 1S4BP 2KRJA 2TCLA 4JA1A 1PWPA 3WV2A 1SRPA 1XFWA 4G0DA 2OW9A 2USNA 1R1IA 1CXVA 3LGPA 2JT5A 4H1QA 3TS4A 4AIGA 1GO8P 3DSLA 3O2XA 1D8FA 1I76A 1HY7A 1ZS0A 2PJTA 3KRYA 4I03A 3ZUKA 1ROSA 1JAQA 4H49A 4FU4A 1JIWP 1O0TA 2Y6CA 1KUIA 1QUAA 3K7LA 5L7FA 3DWBA 1AF0A 3TT4A 1IAEA 3LKAA 3HY7A 1HFCA 1SMPA 2Y6DA 1JAOA 3HY9A 1USNA 1G49A 4JIJA 2E3XA 4G9LA 1RM8A 3EHXA 1BQQM 2OW0A 3HBUP 4XM6A 3Q2GA 3F1AA 1XFUA 2CKIA 4A7BA 1R55A 1GKDA 2WO8A 3LUMA 3USNA 3ZVSA 4H76A 1I73A 2X3CA 3WV3A 1WNIA 2EROA 2CLTA 1BUDA 3KEKA 1OM7A 2OVXA 3F17A 3U1RA 1HV5A 1OMJA 3LQ0A 5BOYA 1OS9A 1QICA 1JJ9A 2FV5A 830CA 1ASTA 1Y0VA
chains in the Genus database with same CATH superfamily
3KWVC 1IACA 1UTZA 2DDYA 5LABA 1MMPA 1Y93A 1YOUA 4PKTA 4R3VA 3LILA 1SATA 5BOTA 1UMTA 1L6JA 3EDGA 3OHOA 5L79A 3WV1A 3LK8A 2I47A 4I35A 1YP1A 1QJIA 1YCMA 1JANA 1IAGA 1FBLA 1G05A 3DPFA 3N2VA 2OXWA 1OS2A 5B5PA 1HOVA 4FXQA 1OM8A 4ON1A 5D1UA 5D1TA 2O3EA 4JP4A 5D1SA 3ZXHA 3DL1A 2AIGP 1CAQA 2QPJA 2YUFA 4GWNA 4PKSA 1BKCI 4WKEA 1K7QA 1ZXCA 3EDIA 3LE9A 2JNPA 4IN9A 3P1VA 2ERPA 4WKIA 1XAXA 3VI1A 3HDBA 2J0TA 1AYKA 1BUVM 3GBOA 3N2UA 4AYKA 3F18A 5I2ZA 1ZTQA 4IUWA 2DW2A 1PWUA 1KUFA 3KEJA 4L6TA 4ILWD 4L63A 4PKVA 1D7XA 4GR0A 4AXQA 3DNGA 4ZR5A 3OHLA 4HMAA 1ATLA 2ERQA 1GKCA 2RJPA 1XM5A 5CUHA 5I12A 4H3XA 2SRTA 3BA0A 1A86A 4GUYA 1Y8JA 2D1OA 2OZRA 1ZXVA 1B3DA 1UMSA 4CTHA 2JT6A 2OW2A 1G4KA 5D7WA 1HTDA 3LEAA 2WOAA 1GE6A 2OXUA 1KUHA 3HB2P 966CA 1HFSA 2MZIA 3O64A 2D1NA 1BKCE 3K7NA 3AYKA 2DDFA 1QIBA 3TVCA 1CGFA 2A8HA 2J83A 4HX3A 3TSKA 5D3CA 3LJTA 2MLSA 1MMRA 3G5CA 1AKLA 2POJA 2W15A 1C7KA 1FLSA 2YIGA 5BPAA 4GQLA 2MZHA 1PWWA 1MNCA 4L19A 2W13A 3UVCA 3B2ZA 4GR3A 1GO7P 1KAPP 1BM6A 1PWVA 2XS3A 4DPEA 3Q2HA 5B5OA 2JSDA 4XCTA 3LJGA 2K9CA 1Z3JA 4PKQA 2DW0A 1G12A 5JMYA 3LJZA 3G42A 3LIRA 1OM6A 1JK3A 456CA 2DW1A 1DMTA 5D2BA 5H8XA 5I3MA 3I7IA 4EFSA 1ZVXA 1ND1A 4XM7A 1RMZA 2OY2A 1CGLA 4WF6A 2WO9A 1JKYA 1O0QA 3ELMA 3KMCA 1CIZA 4H30A 3RTSA 3AIGA 2W14A 1GE5A 1SLMA 3F19A 3B8ZA 1MMBA 1XFZA 4WZVA 2X3AA 1IAAA 1G9KA 3KECA 3LQBA 1R1JA 1EB6A 2MZEA 4H2EA 4AUOA 1R54A 4QKZA 5CXAA 3KHIA 1XUDA 4H84A 3E8RA 1C3IA 4XM8A 1BIWA 2OY4A 3MA2A 3P24A 2E2DA 2OW1A 4PKRA 3VTGA 3NX7A 2MLRA 1GXDA 1QIAA 4PKUA 4WK7A 1C8TA 2OVZA 2K2GA 3L0VA 2YB9A 4J4MA 1KUKA 3LMCA 1IADA 4GWMA 1MMQA 1A85A 1B8YA 1K7GA 1K7IA 1YQYA 3EWJA 4JQGA 2HU6A 1JH1A 4FVLA 1H71P 1D5JA 1R1HA 2FV9A 3LUNA 5I4OA 1Q3AA 4H82A 3V96B 2V4BA 1CQRA 3L0TA 1XFXA 2JIHA 3B92A 1KUGA 1JAPA 4DD8A 2AYKA 3DTEA 2X3BA 1I1IP 1D8MA 1UEAA 2RJQA 2XS4A 4A3WA 3I7GA 2N8RA 3HYGA 1XFYA 3LIKA 4DV8A 4Q1LA 3HBVP 1EUBA 1TVIA 5I0LA 4XBHA 4GF1A 4FXYP 1XFVA 2OI0A 5CZMA 3CKIA 3EDHA 1GE7A 1XURA 1BQOA 1PWQA 4IJOA 1OO9A 1BZSA 1BKCA 1BSWA 2W12A 1DTHA 1FM1A 3EHYA 2O36A 1J7NA 1UTTA 1ZP5A 3AYUA 2Z2DA 3RTTA 2W0DA 3KMEA 4JPAA 1CK7A 3F15A 4GR8A 1EAKA 1CGEA 1SU3A 1XUCA 4PKWA 2L0RA 1QJJA 5I43A 1SLNA 3SHIA 4L7AA 1JIZA 2OXZA 4DF9A 1IABA 3DPEA 2X7MA 3HDAP 3F16A 3EDZA 1KBCA 1S4BP 2KRJA 2TCLA 4JA1A 1PWPA 3WV2A 1SRPA 1XFWA 4G0DA 2OW9A 2USNA 1R1IA 1CXVA 3LGPA 2JT5A 4H1QA 3TS4A 4AIGA 1GO8P 3DSLA 3O2XA 1D8FA 1I76A 1HY7A 1ZS0A 2PJTA 3KRYA 3DTKA 4I03A 3ZUKA 3DTIA 1ROSA 1JAQA 4H49A 4FU4A 1JIWP 1O0TA 2Y6CA 1KUIA 1QUAA 3K7LA 5L7FA 3DWBA 1AF0A 3TT4A 1IAEA 3LKAA 3HY7A 1HFCA 1SMPA 2Y6DA 1JAOA 3HY9A 1USNA 1G49A 4JIJA 2E3XA 4G9LA 1RM8A 3EHXA 1BQQM 2OW0A 3HBUP 4XM6A 3Q2GA 3F1AA 1XFUA 2CKIA 4A7BA 1R55A 1GKDA 2WO8A 3LUMA 3USNA 3ZVSA 4H76A 1I73A 2X3CA 3WV3A 1WNIA 2EROA 2CLTA 1BUDA 3KEKA 1OM7A 2OVXA 3F17A 3U1RA 1HV5A 1OMJA 1OZ9A 3LQ0A 5BOYA 1OS9A 1QICA 1JJ9A 2FV5A 830CA 1ASTA 1Y0VA
chains in the Genus database with same CATH topology
3KWVC 1IACA 1UTZA 2DDYA 5LABA 1MMPA 1Y93A 1YOUA 4PKTA 4R3VA 3LILA 1SATA 5BOTA 1UMTA 1L6JA 3EDGA 3OHOA 5L79A 3WV1A 3LK8A 2I47A 4I35A 1YP1A 1QJIA 1YCMA 1JANA 1IAGA 1FBLA 1G05A 3DPFA 3N2VA 2OXWA 1OS2A 5B5PA 1HOVA 4FXQA 1OM8A 4ON1A 5D1UA 5D1TA 2O3EA 4JP4A 5D1SA 3ZXHA 3DL1A 2AIGP 1CAQA 2QPJA 2YUFA 4GWNA 4PKSA 1BKCI 4WKEA 1K7QA 1ZXCA 3EDIA 3LE9A 2JNPA 4IN9A 3P1VA 2ERPA 4WKIA 3VI1A 3HDBA 2J0TA 1AYKA 1BUVM 3GBOA 3N2UA 4AYKA 3F18A 5I2ZA 1ZTQA 4IUWA 2DW2A 1PWUA 1KUFA 3KEJA 4L6TA 4ILWD 4L63A 4PKVA 1D7XA 4GR0A 4AXQA 3DNGA 4ZR5A 3OHLA 4HMAA 1ATLA 2ERQA 1GKCA 2RJPA 5CUHA 5I12A 4H3XA 2SRTA 3BA0A 1A86A 4GUYA 1Y8JA 2D1OA 2OZRA 1ZXVA 1B3DA 1UMSA 4CTHA 2JT6A 2OW2A 1G4KA 5D7WA 1HTDA 3LEAA 2WOAA 1GE6A 2OXUA 1KUHA 3HB2P 966CA 1HFSA 2MZIA 3O64A 2D1NA 1BKCE 3K7NA 3AYKA 2DDFA 1QIBA 3TVCA 1CGFA 2A8HA 2J83A 4HX3A 3TSKA 5D3CA 3LJTA 2MLSA 1MMRA 3G5CA 1AKLA 2POJA 2W15A 1C7KA 1FLSA 2YIGA 5BPAA 4GQLA 2MZHA 1PWWA 1MNCA 4L19A 2W13A 3UVCA 3B2ZA 4GR3A 1GO7P 1KAPP 1BM6A 1PWVA 2XS3A 4DPEA 3Q2HA 5B5OA 2JSDA 4XCTA 3LJGA 2K9CA 1Z3JA 4PKQA 2DW0A 1G12A 5JMYA 3LJZA 3G42A 3LIRA 1OM6A 1JK3A 456CA 2DW1A 1DMTA 5D2BA 5H8XA 5I3MA 3I7IA 4EFSA 1ZVXA 1ND1A 4XM7A 1RMZA 2OY2A 1CGLA 4WF6A 2WO9A 1JKYA 1O0QA 3ELMA 3KMCA 1CIZA 4H30A 3RTSA 3AIGA 2W14A 1GE5A 1SLMA 3F19A 3B8ZA 1MMBA 1XFZA 4WZVA 2X3AA 1IAAA 1G9KA 3KECA 3LQBA 1R1JA 1EB6A 2MZEA 4H2EA 4AUOA 1R54A 4QKZA 5CXAA 3KHIA 1XUDA 4H84A 3E8RA 1C3IA 4XM8A 1BIWA 2OY4A 3MA2A 3P24A 2E2DA 2OW1A 4PKRA 3VTGA 3NX7A 2MLRA 1GXDA 1QIAA 4PKUA 4WK7A 1C8TA 2OVZA 2K2GA 3L0VA 2YB9A 4J4MA 1KUKA 3LMCA 1IADA 4GWMA 1MMQA 1A85A 1B8YA 1K7GA 1K7IA 1YQYA 3EWJA 4JQGA 2HU6A 1JH1A 4FVLA 1H71P 1D5JA 1R1HA 2FV9A 3LUNA 5I4OA 1Q3AA 4H82A 3V96B 2V4BA 1CQRA 3L0TA 1XFXA 2JIHA 3B92A 1KUGA 1JAPA 4DD8A 2AYKA 3DTEA 2X3BA 1I1IP 1D8MA 1UEAA 2RJQA 2XS4A 4A3WA 3I7GA 2N8RA 3HYGA 1XFYA 3LIKA 4DV8A 4Q1LA 3HBVP 1EUBA 5I0LA 4XBHA 4GF1A 4FXYP 1XFVA 2OI0A 5CZMA 3CKIA 3EDHA 1GE7A 1XURA 1BQOA 1PWQA 4IJOA 1OO9A 1BZSA 1BKCA 1BSWA 2W12A 1DTHA 1FM1A 3EHYA 2O36A 1J7NA 1UTTA 1ZP5A 3AYUA 2Z2DA 3RTTA 2W0DA 3KMEA 4JPAA 1CK7A 3F15A 4GR8A 1EAKA 1CGEA 1SU3A 1XUCA 4PKWA 2L0RA 1QJJA 5I43A 1SLNA 3SHIA 4L7AA 1JIZA 2OXZA 4DF9A 1IABA 3DPEA 2X7MA 3HDAP 3F16A 3EDZA 1KBCA 1S4BP 2KRJA 2TCLA 4JA1A 1PWPA 3WV2A 1SRPA 1XFWA 4G0DA 2OW9A 2USNA 1R1IA 1CXVA 3LGPA 2JT5A 4H1QA 3TS4A 4AIGA 1GO8P 3DSLA 3O2XA 1D8FA 1I76A 1HY7A 1ZS0A 2PJTA 3KRYA 3DTKA 4I03A 3ZUKA 3DTIA 1ROSA 1JAQA 4H49A 4FU4A 1JIWP 1O0TA 2Y6CA 1KUIA 1QUAA 3K7LA 5L7FA 3DWBA 1AF0A 3TT4A 1IAEA 3LKAA 3HY7A 1HFCA 1SMPA 2Y6DA 1JAOA 3HY9A 1USNA 1G49A 4JIJA 2E3XA 4G9LA 1RM8A 3EHXA 1BQQM 2OW0A 3HBUP 4XM6A 3Q2GA 3F1AA 1XFUA 2CKIA 4A7BA 1R55A 1GKDA 2WO8A 3LUMA 3USNA 3ZVSA 4H76A 1I73A 2X3CA 3WV3A 1WNIA 2EROA 2CLTA 1BUDA 3KEKA 1OM7A 2OVXA 3F17A 3U1RA 1HV5A 1OMJA 3LQ0A 5BOYA 1OS9A 1QICA 1JJ9A 2FV5A 830CA 1ASTA 1Y0VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KWV C;  1IAC A;  1UTZ A;  2DDY A;  5LAB A;  1MMP A;  1Y93 A;  1YOU A;  4PKT A;  4R3V A;  3LIL A;  1SAT A;  5BOT A;  1UMT A;  1L6J A;  3EDG A;  3OHO A;  5L79 A;  3WV1 A;  3LK8 A;  2I47 A;  4I35 A;  1YP1 A;  1QJI A;  1YCM A;  1JAN A;  1IAG A;  1FBL A;  1G05 A;  3DPF A;  3N2V A;  2OXW A;  1OS2 A;  5B5P A;  1HOV A;  4FXQ A;  1OM8 A;  4ON1 A;  5D1U A;  5D1T A;  2O3E A;  4JP4 A;  5D1S A;  3ZXH A;  3DL1 A;  2AIG P;  1CAQ A;  2QPJ A;  4GWN A;  4PKS A;  1BKC I;  4WKE A;  1K7Q A;  1ZXC A;  3EDI A;  3LE9 A;  2JNP A;  4IN9 A;  3P1V A;  2ERP A;  4WKI A;  3VI1 A;  3HDB A;  2J0T A;  1AYK A;  1BUV M;  3GBO A;  3N2U A;  4AYK A;  3F18 A;  5I2Z A;  1ZTQ A;  4IUW A;  2DW2 A;  1PWU A;  1KUF A;  3KEJ A;  4L6T A;  4ILW D;  4L63 A;  4PKV A;  1D7X A;  4GR0 A;  4AXQ A;  3DNG A;  4ZR5 A;  3OHL A;  4HMA A;  1ATL A;  2ERQ A;  1GKC A;  2RJP A;  5CUH A;  5I12 A;  4H3X A;  2SRT A;  3BA0 A;  1A86 A;  4GUY A;  1Y8J A;  2D1O A;  2OZR A;  1ZXV A;  1B3D A;  1UMS A;  4CTH A;  2JT6 A;  2OW2 A;  1G4K A;  5D7W A;  1HTD A;  3LEA A;  2WOA A;  1GE6 A;  2OXU A;  1KUH A;  3HB2 P;  966C A;  1HFS A;  2MZI A;  3O64 A;  2D1N A;  1BKC E;  3K7N A;  3AYK A;  2DDF A;  1QIB A;  3TVC A;  1CGF A;  2A8H A;  2J83 A;  4HX3 A;  3TSK A;  5D3C A;  3LJT A;  2MLS A;  1MMR A;  3G5C A;  1AKL A;  2POJ A;  2W15 A;  1C7K A;  1FLS A;  2YIG A;  5BPA A;  4GQL A;  2MZH A;  1PWW A;  1MNC A;  4L19 A;  2W13 A;  3UVC A;  3B2Z A;  4GR3 A;  1GO7 P;  1KAP P;  1BM6 A;  1PWV A;  2XS3 A;  4DPE A;  3Q2H A;  5B5O A;  2JSD A;  4XCT A;  3LJG A;  2K9C A;  1Z3J A;  4PKQ A;  2DW0 A;  1G12 A;  5JMY A;  3LJZ A;  3G42 A;  3LIR A;  1OM6 A;  1JK3 A;  456C A;  2DW1 A;  1DMT A;  5D2B A;  5H8X A;  5I3M A;  3I7I A;  4EFS A;  1ZVX A;  1ND1 A;  4XM7 A;  1RMZ A;  2OY2 A;  1CGL A;  4WF6 A;  2WO9 A;  1JKY A;  1O0Q A;  3ELM A;  3KMC A;  1CIZ A;  4H30 A;  3RTS A;  3AIG A;  2W14 A;  1GE5 A;  1SLM A;  3F19 A;  3B8Z A;  1MMB A;  1XFZ A;  4WZV A;  2X3A A;  1IAA A;  1G9K A;  3KEC A;  3LQB A;  1R1J A;  1EB6 A;  2MZE A;  4H2E A;  4AUO A;  1R54 A;  4QKZ A;  5CXA A;  3KHI A;  1XUD A;  4H84 A;  3E8R A;  1C3I A;  4XM8 A;  1BIW A;  2OY4 A;  3MA2 A;  3P24 A;  2E2D A;  2OW1 A;  4PKR A;  3VTG A;  3NX7 A;  2MLR A;  1GXD A;  1QIA A;  4PKU A;  4WK7 A;  1C8T A;  2OVZ A;  2K2G A;  3L0V A;  2YB9 A;  4J4M A;  1KUK A;  3LMC A;  1IAD A;  4GWM A;  1MMQ A;  1A85 A;  1B8Y A;  1K7G A;  1K7I A;  1YQY A;  3EWJ A;  4JQG A;  2HU6 A;  1JH1 A;  4FVL A;  1H71 P;  1D5J A;  1R1H A;  2FV9 A;  3LUN A;  5I4O A;  1Q3A A;  4H82 A;  3V96 B;  2V4B A;  1CQR A;  3L0T A;  1XFX A;  2JIH A;  3B92 A;  1KUG A;  1JAP A;  4DD8 A;  2AYK A;  2X3B A;  1I1I P;  1D8M A;  1UEA A;  2RJQ A;  2XS4 A;  4A3W A;  3I7G A;  2N8R A;  3HYG A;  1XFY A;  3LIK A;  4DV8 A;  4Q1L A;  3HBV P;  1EUB A;  5I0L A;  4XBH A;  4GF1 A;  4FXY P;  1XFV A;  2OI0 A;  5CZM A;  3CKI A;  3EDH A;  1GE7 A;  1XUR A;  1BQO A;  1PWQ A;  4IJO A;  1OO9 A;  1BZS A;  1BKC A;  1BSW A;  2W12 A;  1DTH A;  1FM1 A;  3EHY A;  2O36 A;  1J7N A;  1UTT A;  1ZP5 A;  3AYU A;  2Z2D A;  3RTT A;  2W0D A;  3KME A;  4JPA A;  1CK7 A;  3F15 A;  4GR8 A;  1EAK A;  1CGE A;  1SU3 A;  1XUC A;  4PKW A;  2L0R A;  1QJJ A;  5I43 A;  1SLN A;  3SHI A;  1JIZ A;  2OXZ A;  4DF9 A;  1IAB A;  3DPE A;  2X7M A;  3HDA P;  3F16 A;  3EDZ A;  1KBC A;  1S4B P;  2KRJ A;  2TCL A;  4JA1 A;  1PWP A;  3WV2 A;  1SRP A;  1XFW A;  4G0D A;  2OW9 A;  2USN A;  1R1I A;  1CXV A;  3LGP A;  2JT5 A;  4H1Q A;  3TS4 A;  4AIG A;  1GO8 P;  3DSL A;  3O2X A;  1D8F A;  1I76 A;  1HY7 A;  1ZS0 A;  2PJT A;  3KRY A;  4I03 A;  3ZUK A;  1ROS A;  1JAQ A;  4H49 A;  4FU4 A;  1JIW P;  1O0T A;  2Y6C A;  1KUI A;  1QUA A;  3K7L A;  5L7F A;  3DWB A;  1AF0 A;  3TT4 A;  1IAE A;  3LKA A;  3HY7 A;  1HFC A;  1SMP A;  2Y6D A;  1JAO A;  3HY9 A;  1USN A;  1G49 A;  4JIJ A;  2E3X A;  4G9L A;  1RM8 A;  3EHX A;  1BQQ M;  2OW0 A;  3HBU P;  4XM6 A;  3Q2G A;  3F1A A;  1XFU A;  2CKI A;  4A7B A;  1R55 A;  1GKD A;  2WO8 A;  3LUM A;  3USN A;  3ZVS A;  4H76 A;  1I73 A;  2X3C A;  3WV3 A;  1WNI A;  2ERO A;  2CLT A;  1BUD A;  3KEK A;  1OM7 A;  2OVX A;  3F17 A;  3U1R A;  1HV5 A;  1OMJ A;  3LQ0 A;  5BOY A;  1OS9 A;  1QIC A;  1JJ9 A;  2FV5 A;  830C A;  1AST A;  1Y0V A; 
#chains in the Genus database with same CATH topology
 3KWV C;  1IAC A;  1UTZ A;  2DDY A;  5LAB A;  1MMP A;  1Y93 A;  1YOU A;  4PKT A;  4R3V A;  3LIL A;  1SAT A;  5BOT A;  1UMT A;  1L6J A;  3EDG A;  3OHO A;  5L79 A;  3WV1 A;  3LK8 A;  2I47 A;  4I35 A;  1YP1 A;  1QJI A;  1YCM A;  1JAN A;  1IAG A;  1FBL A;  1G05 A;  3DPF A;  3N2V A;  2OXW A;  1OS2 A;  5B5P A;  1HOV A;  4FXQ A;  1OM8 A;  4ON1 A;  5D1U A;  5D1T A;  2O3E A;  4JP4 A;  5D1S A;  3ZXH A;  3DL1 A;  2AIG P;  1CAQ A;  2QPJ A;  2YUF A;  4GWN A;  4PKS A;  1BKC I;  4WKE A;  1K7Q A;  1ZXC A;  3EDI A;  3LE9 A;  2JNP A;  4IN9 A;  3P1V A;  2ERP A;  4WKI A;  1XAX A;  3VI1 A;  3HDB A;  2J0T A;  1AYK A;  1BUV M;  3GBO A;  3N2U A;  4AYK A;  3F18 A;  5I2Z A;  1ZTQ A;  4IUW A;  2DW2 A;  1PWU A;  1KUF A;  3KEJ A;  4L6T A;  4ILW D;  4L63 A;  4PKV A;  1D7X A;  4GR0 A;  4AXQ A;  3DNG A;  4ZR5 A;  3OHL A;  4HMA A;  1ATL A;  2ERQ A;  1GKC A;  2RJP A;  1XM5 A;  5CUH A;  5I12 A;  4H3X A;  2SRT A;  3BA0 A;  1A86 A;  4GUY A;  1Y8J A;  2D1O A;  2OZR A;  1ZXV A;  1B3D A;  1UMS A;  4CTH A;  2JT6 A;  2OW2 A;  1G4K A;  5D7W A;  1HTD A;  3LEA A;  2WOA A;  1GE6 A;  2OXU A;  1KUH A;  3HB2 P;  966C A;  1HFS A;  2MZI A;  3O64 A;  2D1N A;  1BKC E;  3K7N A;  3AYK A;  2DDF A;  1QIB A;  3TVC A;  1CGF A;  2A8H A;  2J83 A;  4HX3 A;  3TSK A;  5D3C A;  3LJT A;  2MLS A;  1MMR A;  3G5C A;  1AKL A;  2POJ A;  2W15 A;  1C7K A;  1FLS A;  2YIG A;  5BPA A;  4GQL A;  2MZH A;  1PWW A;  1MNC A;  4L19 A;  2W13 A;  3UVC A;  3B2Z A;  4GR3 A;  1GO7 P;  1KAP P;  1BM6 A;  1PWV A;  2XS3 A;  4DPE A;  3Q2H A;  5B5O A;  2JSD A;  4XCT A;  3LJG A;  2K9C A;  1Z3J A;  4PKQ A;  2DW0 A;  1G12 A;  5JMY A;  3LJZ A;  3G42 A;  3LIR A;  1OM6 A;  1JK3 A;  456C A;  2DW1 A;  1DMT A;  5D2B A;  5H8X A;  5I3M A;  3I7I A;  4EFS A;  1ZVX A;  1ND1 A;  4XM7 A;  1RMZ A;  2OY2 A;  1CGL A;  4WF6 A;  2WO9 A;  1JKY A;  1O0Q A;  3ELM A;  3KMC A;  1CIZ A;  4H30 A;  3RTS A;  3AIG A;  2W14 A;  1GE5 A;  1SLM A;  3F19 A;  3B8Z A;  1MMB A;  1XFZ A;  4WZV A;  2X3A A;  1IAA A;  1G9K A;  3KEC A;  3LQB A;  1R1J A;  1EB6 A;  2MZE A;  4H2E A;  4AUO A;  1R54 A;  4QKZ A;  5CXA A;  3KHI A;  1XUD A;  4H84 A;  3E8R A;  1C3I A;  4XM8 A;  1BIW A;  2OY4 A;  3MA2 A;  3P24 A;  2E2D A;  2OW1 A;  4PKR A;  3VTG A;  3NX7 A;  2MLR A;  1GXD A;  1QIA A;  4PKU A;  4WK7 A;  1C8T A;  2OVZ A;  2K2G A;  3L0V A;  2YB9 A;  4J4M A;  1KUK A;  3LMC A;  1IAD A;  4GWM A;  1MMQ A;  1A85 A;  1B8Y A;  1K7G A;  1K7I A;  1YQY A;  3EWJ A;  4JQG A;  2HU6 A;  1JH1 A;  4FVL A;  1H71 P;  1D5J A;  1R1H A;  2FV9 A;  3LUN A;  5I4O A;  1Q3A A;  4H82 A;  3V96 B;  2V4B A;  1CQR A;  3L0T A;  1XFX A;  2JIH A;  3B92 A;  1KUG A;  1JAP A;  4DD8 A;  2AYK A;  3DTE A;  2X3B A;  1I1I P;  1D8M A;  1UEA A;  2RJQ A;  2XS4 A;  4A3W A;  3I7G A;  2N8R A;  3HYG A;  1XFY A;  3LIK A;  4DV8 A;  4Q1L A;  3HBV P;  1EUB A;  1TVI A;  5I0L A;  4XBH A;  4GF1 A;  4FXY P;  1XFV A;  2OI0 A;  5CZM A;  3CKI A;  3EDH A;  1GE7 A;  1XUR A;  1BQO A;  1PWQ A;  4IJO A;  1OO9 A;  1BZS A;  1BKC A;  1BSW A;  2W12 A;  1DTH A;  1FM1 A;  3EHY A;  2O36 A;  1J7N A;  1UTT A;  1ZP5 A;  3AYU A;  2Z2D A;  3RTT A;  2W0D A;  3KME A;  4JPA A;  1CK7 A;  3F15 A;  4GR8 A;  1EAK A;  1CGE A;  1SU3 A;  1XUC A;  4PKW A;  2L0R A;  1QJJ A;  5I43 A;  1SLN A;  3SHI A;  4L7A A;  1JIZ A;  2OXZ A;  4DF9 A;  1IAB A;  3DPE A;  2X7M A;  3HDA P;  3F16 A;  3EDZ A;  1KBC A;  1S4B P;  2KRJ A;  2TCL A;  4JA1 A;  1PWP A;  3WV2 A;  1SRP A;  1XFW A;  4G0D A;  2OW9 A;  2USN A;  1R1I A;  1CXV A;  3LGP A;  2JT5 A;  4H1Q A;  3TS4 A;  4AIG A;  1GO8 P;  3DSL A;  3O2X A;  1D8F A;  1I76 A;  1HY7 A;  1ZS0 A;  2PJT A;  3KRY A;  3DTK A;  4I03 A;  3ZUK A;  3DTI A;  1ROS A;  1JAQ A;  4H49 A;  4FU4 A;  1JIW P;  1O0T A;  2Y6C A;  1KUI A;  1QUA A;  3K7L A;  5L7F A;  3DWB A;  1AF0 A;  3TT4 A;  1IAE A;  3LKA A;  3HY7 A;  1HFC A;  1SMP A;  2Y6D A;  1JAO A;  3HY9 A;  1USN A;  1G49 A;  4JIJ A;  2E3X A;  4G9L A;  1RM8 A;  3EHX A;  1BQQ M;  2OW0 A;  3HBU P;  4XM6 A;  3Q2G A;  3F1A A;  1XFU A;  2CKI A;  4A7B A;  1R55 A;  1GKD A;  2WO8 A;  3LUM A;  3USN A;  3ZVS A;  4H76 A;  1I73 A;  2X3C A;  3WV3 A;  1WNI A;  2ERO A;  2CLT A;  1BUD A;  3KEK A;  1OM7 A;  2OVX A;  3F17 A;  3U1R A;  1HV5 A;  1OMJ A;  1OZ9 A;  3LQ0 A;  5BOY A;  1OS9 A;  1QIC A;  1JJ9 A;  2FV5 A;  830C A;  1AST A;  1Y0V A; 
#chains in the Genus database with same CATH homology
 3KWV C;  1IAC A;  1UTZ A;  2DDY A;  5LAB A;  1MMP A;  1Y93 A;  1YOU A;  4PKT A;  4R3V A;  3LIL A;  1SAT A;  5BOT A;  1UMT A;  1L6J A;  3EDG A;  3OHO A;  5L79 A;  3WV1 A;  3LK8 A;  2I47 A;  4I35 A;  1YP1 A;  1QJI A;  1YCM A;  1JAN A;  1IAG A;  1FBL A;  1G05 A;  3DPF A;  3N2V A;  2OXW A;  1OS2 A;  5B5P A;  1HOV A;  4FXQ A;  1OM8 A;  4ON1 A;  5D1U A;  5D1T A;  2O3E A;  4JP4 A;  5D1S A;  3ZXH A;  3DL1 A;  2AIG P;  1CAQ A;  2QPJ A;  2YUF A;  4GWN A;  4PKS A;  1BKC I;  4WKE A;  1K7Q A;  1ZXC A;  3EDI A;  3LE9 A;  2JNP A;  4IN9 A;  3P1V A;  2ERP A;  4WKI A;  3VI1 A;  3HDB A;  2J0T A;  1AYK A;  1BUV M;  3GBO A;  3N2U A;  4AYK A;  3F18 A;  5I2Z A;  1ZTQ A;  4IUW A;  2DW2 A;  1PWU A;  1KUF A;  3KEJ A;  4L6T A;  4ILW D;  4L63 A;  4PKV A;  1D7X A;  4GR0 A;  4AXQ A;  3DNG A;  4ZR5 A;  3OHL A;  4HMA A;  1ATL A;  2ERQ A;  1GKC A;  2RJP A;  5CUH A;  5I12 A;  4H3X A;  2SRT A;  3BA0 A;  1A86 A;  4GUY A;  1Y8J A;  2D1O A;  2OZR A;  1ZXV A;  1B3D A;  1UMS A;  4CTH A;  2JT6 A;  2OW2 A;  1G4K A;  5D7W A;  1HTD A;  3LEA A;  2WOA A;  1GE6 A;  2OXU A;  1KUH A;  3HB2 P;  966C A;  1HFS A;  2MZI A;  3O64 A;  2D1N A;  1BKC E;  3K7N A;  3AYK A;  2DDF A;  1QIB A;  3TVC A;  1CGF A;  2A8H A;  2J83 A;  4HX3 A;  3TSK A;  5D3C A;  3LJT A;  2MLS A;  1MMR A;  3G5C A;  1AKL A;  2POJ A;  2W15 A;  1C7K A;  1FLS A;  2YIG A;  5BPA A;  4GQL A;  2MZH A;  1PWW A;  1MNC A;  4L19 A;  2W13 A;  3UVC A;  3B2Z A;  4GR3 A;  1GO7 P;  1KAP P;  1BM6 A;  1PWV A;  2XS3 A;  4DPE A;  3Q2H A;  5B5O A;  2JSD A;  4XCT A;  3LJG A;  2K9C A;  1Z3J A;  4PKQ A;  2DW0 A;  1G12 A;  5JMY A;  3LJZ A;  3G42 A;  3LIR A;  1OM6 A;  1JK3 A;  456C A;  2DW1 A;  1DMT A;  5D2B A;  5H8X A;  5I3M A;  3I7I A;  4EFS A;  1ZVX A;  1ND1 A;  4XM7 A;  1RMZ A;  2OY2 A;  1CGL A;  4WF6 A;  2WO9 A;  1JKY A;  1O0Q A;  3ELM A;  3KMC A;  1CIZ A;  4H30 A;  3RTS A;  3AIG A;  2W14 A;  1GE5 A;  1SLM A;  3F19 A;  3B8Z A;  1MMB A;  1XFZ A;  4WZV A;  2X3A A;  1IAA A;  1G9K A;  3KEC A;  3LQB A;  1R1J A;  1EB6 A;  2MZE A;  4H2E A;  4AUO A;  1R54 A;  4QKZ A;  5CXA A;  3KHI A;  1XUD A;  4H84 A;  3E8R A;  1C3I A;  4XM8 A;  1BIW A;  2OY4 A;  3MA2 A;  3P24 A;  2E2D A;  2OW1 A;  4PKR A;  3VTG A;  3NX7 A;  2MLR A;  1GXD A;  1QIA A;  4PKU A;  4WK7 A;  1C8T A;  2OVZ A;  2K2G A;  3L0V A;  2YB9 A;  4J4M A;  1KUK A;  3LMC A;  1IAD A;  4GWM A;  1MMQ A;  1A85 A;  1B8Y A;  1K7G A;  1K7I A;  1YQY A;  3EWJ A;  4JQG A;  2HU6 A;  1JH1 A;  4FVL A;  1H71 P;  1D5J A;  1R1H A;  2FV9 A;  3LUN A;  5I4O A;  1Q3A A;  4H82 A;  3V96 B;  2V4B A;  1CQR A;  3L0T A;  1XFX A;  2JIH A;  3B92 A;  1KUG A;  1JAP A;  4DD8 A;  2AYK A;  3DTE A;  2X3B A;  1I1I P;  1D8M A;  1UEA A;  2RJQ A;  2XS4 A;  4A3W A;  3I7G A;  2N8R A;  3HYG A;  1XFY A;  3LIK A;  4DV8 A;  4Q1L A;  3HBV P;  1EUB A;  5I0L A;  4XBH A;  4GF1 A;  4FXY P;  1XFV A;  2OI0 A;  5CZM A;  3CKI A;  3EDH A;  1GE7 A;  1XUR A;  1BQO A;  1PWQ A;  4IJO A;  1OO9 A;  1BZS A;  1BKC A;  1BSW A;  2W12 A;  1DTH A;  1FM1 A;  3EHY A;  2O36 A;  1J7N A;  1UTT A;  1ZP5 A;  3AYU A;  2Z2D A;  3RTT A;  2W0D A;  3KME A;  4JPA A;  1CK7 A;  3F15 A;  4GR8 A;  1EAK A;  1CGE A;  1SU3 A;  1XUC A;  4PKW A;  2L0R A;  1QJJ A;  5I43 A;  1SLN A;  3SHI A;  4L7A A;  1JIZ A;  2OXZ A;  4DF9 A;  1IAB A;  3DPE A;  2X7M A;  3HDA P;  3F16 A;  3EDZ A;  1KBC A;  1S4B P;  2KRJ A;  2TCL A;  4JA1 A;  1PWP A;  3WV2 A;  1SRP A;  1XFW A;  4G0D A;  2OW9 A;  2USN A;  1R1I A;  1CXV A;  3LGP A;  2JT5 A;  4H1Q A;  3TS4 A;  4AIG A;  1GO8 P;  3DSL A;  3O2X A;  1D8F A;  1I76 A;  1HY7 A;  1ZS0 A;  2PJT A;  3KRY A;  3DTK A;  4I03 A;  3ZUK A;  3DTI A;  1ROS A;  1JAQ A;  4H49 A;  4FU4 A;  1JIW P;  1O0T A;  2Y6C A;  1KUI A;  1QUA A;  3K7L A;  5L7F A;  3DWB A;  1AF0 A;  3TT4 A;  1IAE A;  3LKA A;  3HY7 A;  1HFC A;  1SMP A;  2Y6D A;  1JAO A;  3HY9 A;  1USN A;  1G49 A;  4JIJ A;  2E3X A;  4G9L A;  1RM8 A;  3EHX A;  1BQQ M;  2OW0 A;  3HBU P;  4XM6 A;  3Q2G A;  3F1A A;  1XFU A;  2CKI A;  4A7B A;  1R55 A;  1GKD A;  2WO8 A;  3LUM A;  3USN A;  3ZVS A;  4H76 A;  1I73 A;  2X3C A;  3WV3 A;  1WNI A;  2ERO A;  2CLT A;  1BUD A;  3KEK A;  1OM7 A;  2OVX A;  3F17 A;  3U1R A;  1HV5 A;  1OMJ A;  3LQ0 A;  5BOY A;  1OS9 A;  1QIC A;  1JJ9 A;  2FV5 A;  830C A;  1AST A;  1Y0V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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