1ZXCA

Crystal structure of catalytic domain of tnf-alpha converting enzyme (tace) with inhibitor
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
259
structure length
259
Chain Sequence
DPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Acetylenic TACE inhibitors. Part 2: SAR of six-membered cyclic sulfonamide hydroxamates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ADAM 17
total genus 87
structure length 259
sequence length 259
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2005-06-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1zxcA00
4AUOA 4H1QA 4XBHA 2OW0A 3KRYA 2N8RA 3L0VA 2OY4A 2CKIA 1USNA 2DW1A 5JMYA 3N2VA 1XUCA 3LK8A 4HMAA 2YB9A 4IN9A 3MA2A 3F16A 1RM8A 3EDHA 2X7MA 1ZXVA 1GE5A 1MMQA 3HBVP 4L6TA 4L19A 5CXAA 4FVLA 1CGLA 4Q1LA 3AIGA 1PWPA 3Q2GA 1ND1A 2K2GA 2X3CA 3BA0A 3KMCA 1K7IA 1JKYA 2I47A 1I76A 4JQGA 5H8XA 4J4MA 1R54A 1GO7P 2MZHA 5CZMA 2L0RA 1OM8A 2JT6A 2SRTA 1R1IA 2ERPA 2AIGP 1UTZA 2DW2A 2OVXA 3WV1A 4QKZA 1GO8P 3VI1A 3KEJA 1G49A 1PWWA 2JIHA 2ERQA 3SHIA 3DWBA 1BIWA 1R1JA 1G9KA 1H71P 1KUGA 2J0TA 1OM7A 2EROA 1XFXA 3LGPA 1G4KA 2JNPA 1IAAA 2JT5A 4H30A 1YP1A 1DMTA 1CXVA 3HBUP 3KMEA 3KHIA 4H76A 4XCTA 3HDAP 2W15A 1AYKA 5LABA 1KUHA 4XM8A 1GE7A 2W12A 2W0DA 1OMJA 4FXYP 1ASTA 4PKVA 1ZP5A 4AXQA 2Y6CA 4PKUA 5L7FA 2OVZA 3K7NA 3AYUA 3LUNA 2OI0A 1BQOA 4GWMA 1MMRA 4IJOA 1IABA 2HU6A 1BKCE 2AYKA 2OZRA 4PKWA 1I1IP 5B5PA 1BSWA 1K7GA 1G05A 2O3EA 1OS9A 3LQ0A 4DF9A 2PJTA 1JJ9A 3B2ZA 3O2XA 2W13A 1XFYA 1XFUA 5L79A 3G5CA 4AYKA 2CLTA 2Z2DA 2XS4A 1R1HA 3N2UA 1SU3A 1JH1A 3EWJA 1R55A 1DTHA 4ILWD 1JK3A 3WV2A 1HV5A 3F17A 3P1VA 1JIWP 1KUFA 1O0QA 1XFVA 1BM6A 4GQLA 2YIGA 3K7LA 3G42A 4CTHA 2J83A 1QJJA 3GBOA 1IADA 3LIKA 4A3WA 966CA 1ROSA 4IUWA 1HOVA 4WKIA 5BOYA 1D5JA 1C7KA 1FLSA 3LQBA 1KAPP 4WK7A 2JSDA 2RJPA 2K9CA 3EHYA 1Q3AA 5BPAA 3LKAA 4JA1A 2O36A 2X3BA 5D3CA 1MMBA 2X3AA 2MZIA 2V4BA 5I43A 1KBCA 1JAPA 1BKCA 2RJQA 1A85A 5CUHA 5I2ZA 2DDFA 1XURA 4G0DA 3F1AA 1KUKA 1BUDA 5I12A 1A86A 3LILA 5BOTA 3F15A 5D1UA 5B5OA 1MNCA 1D8FA 3U1RA 1JAQA 1CGEA 4DV8A 3Q2HA 5I0LA 3P24A 5D7WA 1SLMA 1HY7A 3OHOA 2A8HA 4WZVA 1EAKA 4G9LA 3TT4A 1L6JA 2OW9A 1GE6A 1Y0VA 4WF6A 3ZXHA 2OW2A 1ATLA 2D1NA 1SLNA 2KRJA 4PKRA 1GKCA 4JIJA 1GXDA 3EDGA 3LJGA 3L0TA 1EB6A 1CAQA 3AYKA 2OY2A 1QJIA 3RTTA 1SMPA 1CGFA 4ON1A 1C8TA 3B92A 3F18A 1FM1A 2USNA 1K7QA 1QIAA 1GKDA 1WNIA 4H3XA 1CQRA 3HY9A 5D1TA 4XM7A 3LJTA 1OM6A 5D2BA 5I3MA 1KUIA 4I03A 4JP4A 2W14A 3HY7A 3B8ZA 4WKEA 1HFSA 1UEAA 1YOUA 1D7XA 3EDIA 1RMZA 2FV5A 2OXWA 1EUBA 3DSLA 1BQQM 2OW1A 4H82A 1C3IA 3ELMA 4DPEA 3DPEA 3UVCA 1G12A 1OO9A 1CIZA 1B8YA 1ZVXA 2E2DA 3CKIA 3EHXA 1BZSA 1O0TA 1SATA 3LMCA 2WOAA 1J7NA 1QICA 4GR3A 3DPFA 3USNA 1HTDA 4H84A 3O64A 3ZUKA 2WO8A 1XFZA 4PKSA 456CA 1FBLA 1JANA 4DD8A 2MZEA 4H49A 3V96B 1Z3JA 1SRPA 4GWNA 3EDZA 2DDYA 830CA 4GR0A 3ZVSA 1YQYA 1XUDA 1QUAA 1IACA 4FU4A 3DL1A 1Y93A 4FXQA 3NX7A 1BKCI 3LEAA 1AF0A 3E8RA 3I7GA 2WO9A 1UMTA 3LIRA 2D1OA 1QIBA 3DNGA 3RTSA 2DW0A 3HDBA 4GF1A 4R3VA 3VTGA 3OHLA 2TCLA 1PWVA 4GUYA 4H2EA 4L63A 2E3XA 2FV9A 2POJA 1I73A 1UTTA 3TSKA 1HFCA 2MLSA 4EFSA 2XS3A 1OS2A 3HYGA 2QPJA 3KECA 1PWUA 2Y6DA 1JIZA 4AIGA 3LUMA 3LJZA 2OXZA 1Y8JA 4HX3A 1JAOA 3I7IA 1MMPA 1XFWA 1S4BP 4PKQA 1ZS0A 1UMSA 3HB2P 4GR8A 1ZXCA 5D1SA 2MLRA 1AKLA 1YCMA 3LE9A 4ZR5A 1IAGA 1BUVM 3TVCA 4XM6A 3KWVC 1CK7A 4A7BA 3TS4A 4JPAA 1ZTQA 5I4OA 3WV3A 4PKTA 1B3DA 1D8MA 1IAEA 1PWQA 2OXUA 3KEKA 3F19A 4I35A
chains in the Genus database with same CATH superfamily
4AUOA 4H1QA 4XBHA 2OW0A 3KRYA 2N8RA 3DTEA 3L0VA 2OY4A 2CKIA 1USNA 2DW1A 5JMYA 3N2VA 1XUCA 3LK8A 4HMAA 2YB9A 4IN9A 3MA2A 3F16A 1RM8A 3EDHA 2X7MA 1ZXVA 1GE5A 1MMQA 3HBVP 4L6TA 4L19A 5CXAA 4FVLA 1CGLA 4Q1LA 3AIGA 1PWPA 3Q2GA 1ND1A 2K2GA 2X3CA 3BA0A 3KMCA 1K7IA 1JKYA 2I47A 1I76A 4JQGA 5H8XA 4J4MA 1R54A 1GO7P 2MZHA 5CZMA 2L0RA 1OM8A 2JT6A 2SRTA 1R1IA 1TVIA 2ERPA 2AIGP 1UTZA 2DW2A 2OVXA 3WV1A 4QKZA 1GO8P 3VI1A 3KEJA 1G49A 1PWWA 2JIHA 2ERQA 3SHIA 3DWBA 1BIWA 1R1JA 1G9KA 1H71P 1KUGA 2J0TA 1OM7A 2EROA 1XFXA 3LGPA 1G4KA 2JNPA 1IAAA 2JT5A 4H30A 1XM5A 1YP1A 1DMTA 1CXVA 3HBUP 3KMEA 3KHIA 4H76A 4XCTA 3HDAP 2W15A 1AYKA 5LABA 1KUHA 4XM8A 1GE7A 2W12A 2W0DA 1OMJA 4FXYP 1ASTA 4PKVA 1ZP5A 4AXQA 2Y6CA 4PKUA 5L7FA 2OVZA 3K7NA 3AYUA 3LUNA 2OI0A 1BQOA 4GWMA 1MMRA 4IJOA 1IABA 2HU6A 1BKCE 2AYKA 2OZRA 4PKWA 1I1IP 5B5PA 1BSWA 1K7GA 1G05A 2O3EA 1OS9A 3LQ0A 4DF9A 2PJTA 1JJ9A 3B2ZA 3O2XA 2W13A 1XFYA 1XFUA 5L79A 3G5CA 4AYKA 2CLTA 2Z2DA 2XS4A 1R1HA 3N2UA 1SU3A 1JH1A 3EWJA 1R55A 1DTHA 4ILWD 1JK3A 3WV2A 1HV5A 3F17A 3P1VA 1JIWP 1KUFA 1O0QA 1XFVA 1BM6A 4GQLA 2YIGA 3K7LA 3G42A 4CTHA 2J83A 1QJJA 3GBOA 1IADA 3LIKA 4A3WA 966CA 1ROSA 4IUWA 1HOVA 4WKIA 5BOYA 1D5JA 1C7KA 1FLSA 3LQBA 1KAPP 4WK7A 2JSDA 2RJPA 2K9CA 3EHYA 1Q3AA 5BPAA 3LKAA 4JA1A 2O36A 2X3BA 5D3CA 1MMBA 2X3AA 2MZIA 2V4BA 5I43A 1KBCA 1JAPA 1BKCA 2RJQA 1A85A 5CUHA 5I2ZA 2DDFA 1XURA 4G0DA 3F1AA 1KUKA 1BUDA 5I12A 1A86A 3LILA 4L7AA 5BOTA 3F15A 5D1UA 3DTIA 5B5OA 1MNCA 1D8FA 3U1RA 1JAQA 1CGEA 4DV8A 3Q2HA 5I0LA 3P24A 5D7WA 1SLMA 1HY7A 3OHOA 2A8HA 4WZVA 1EAKA 4G9LA 3TT4A 1L6JA 2OW9A 1GE6A 1Y0VA 4WF6A 3ZXHA 2OW2A 1ATLA 2D1NA 1SLNA 2KRJA 4PKRA 1GKCA 3DTKA 4JIJA 1GXDA 3EDGA 3LJGA 3L0TA 1EB6A 1CAQA 3AYKA 2OY2A 1QJIA 3RTTA 1SMPA 1CGFA 4ON1A 1C8TA 3B92A 3F18A 1FM1A 2USNA 1K7QA 1QIAA 1GKDA 1WNIA 4H3XA 1CQRA 3HY9A 5D1TA 4XM7A 3LJTA 1OM6A 5D2BA 5I3MA 1KUIA 4I03A 4JP4A 2W14A 3HY7A 3B8ZA 4WKEA 1HFSA 1UEAA 1YOUA 1D7XA 3EDIA 1RMZA 2FV5A 2OXWA 1EUBA 3DSLA 1BQQM 2OW1A 4H82A 1C3IA 3ELMA 4DPEA 3DPEA 3UVCA 1G12A 1OO9A 1CIZA 1B8YA 1ZVXA 2E2DA 3CKIA 3EHXA 1BZSA 1O0TA 1SATA 3LMCA 2WOAA 1J7NA 1QICA 4GR3A 3DPFA 3USNA 1HTDA 4H84A 3O64A 3ZUKA 2WO8A 1XFZA 4PKSA 456CA 1FBLA 1JANA 4DD8A 2MZEA 4H49A 3V96B 1Z3JA 1SRPA 4GWNA 3EDZA 2DDYA 830CA 4GR0A 3ZVSA 1YQYA 1XUDA 1QUAA 1IACA 4FU4A 3DL1A 1Y93A 4FXQA 3NX7A 1BKCI 3LEAA 1AF0A 3E8RA 3I7GA 2WO9A 1UMTA 3LIRA 2D1OA 1QIBA 3DNGA 3RTSA 2DW0A 3HDBA 4GF1A 4R3VA 3VTGA 3OHLA 2TCLA 1PWVA 1XAXA 4GUYA 4H2EA 4L63A 2E3XA 2FV9A 2POJA 1I73A 1UTTA 3TSKA 1HFCA 2MLSA 2YUFA 4EFSA 2XS3A 1OS2A 3HYGA 2QPJA 1OZ9A 3KECA 1PWUA 2Y6DA 1JIZA 4AIGA 3LUMA 3LJZA 2OXZA 1Y8JA 4HX3A 1JAOA 3I7IA 1MMPA 1XFWA 1S4BP 4PKQA 1ZS0A 1UMSA 3HB2P 4GR8A 1ZXCA 5D1SA 2MLRA 1AKLA 1YCMA 3LE9A 4ZR5A 1IAGA 1BUVM 3TVCA 4XM6A 3KWVC 1CK7A 4A7BA 3TS4A 4JPAA 1ZTQA 5I4OA 3WV3A 4PKTA 1B3DA 1D8MA 1IAEA 1PWQA 2OXUA 3KEKA 3F19A 4I35A
chains in the Genus database with same CATH topology
4AUOA 4H1QA 4XBHA 2OW0A 3KRYA 2N8RA 3DTEA 3L0VA 2OY4A 2CKIA 1USNA 2DW1A 5JMYA 3N2VA 1XUCA 3LK8A 4HMAA 2YB9A 4IN9A 3MA2A 3F16A 1RM8A 3EDHA 2X7MA 1ZXVA 1GE5A 1MMQA 3HBVP 4L6TA 4L19A 5CXAA 4FVLA 1CGLA 4Q1LA 3AIGA 1PWPA 3Q2GA 1ND1A 2K2GA 2X3CA 3BA0A 3KMCA 1K7IA 1JKYA 2I47A 1I76A 4JQGA 5H8XA 4J4MA 1R54A 1GO7P 2MZHA 5CZMA 2L0RA 1OM8A 2JT6A 2SRTA 1R1IA 2ERPA 2AIGP 1UTZA 2DW2A 2OVXA 3WV1A 4QKZA 1GO8P 3VI1A 3KEJA 1G49A 1PWWA 2JIHA 2ERQA 3SHIA 3DWBA 1BIWA 1R1JA 1G9KA 1H71P 1KUGA 2J0TA 1OM7A 2EROA 1XFXA 3LGPA 1G4KA 2JNPA 1IAAA 2JT5A 4H30A 1YP1A 1DMTA 1CXVA 3HBUP 3KMEA 3KHIA 4H76A 4XCTA 3HDAP 2W15A 1AYKA 5LABA 1KUHA 4XM8A 1GE7A 2W12A 2W0DA 1OMJA 4FXYP 1ASTA 4PKVA 1ZP5A 4AXQA 2Y6CA 4PKUA 5L7FA 2OVZA 3K7NA 3AYUA 3LUNA 2OI0A 1BQOA 4GWMA 1MMRA 4IJOA 1IABA 2HU6A 1BKCE 2AYKA 2OZRA 4PKWA 1I1IP 5B5PA 1BSWA 1K7GA 1G05A 2O3EA 1OS9A 3LQ0A 4DF9A 2PJTA 1JJ9A 3B2ZA 3O2XA 2W13A 1XFYA 1XFUA 5L79A 3G5CA 4AYKA 2CLTA 2Z2DA 2XS4A 1R1HA 3N2UA 1SU3A 1JH1A 3EWJA 1R55A 1DTHA 4ILWD 1JK3A 3WV2A 1HV5A 3F17A 3P1VA 1JIWP 1KUFA 1O0QA 1XFVA 1BM6A 4GQLA 2YIGA 3K7LA 3G42A 4CTHA 2J83A 1QJJA 3GBOA 1IADA 3LIKA 4A3WA 966CA 1ROSA 4IUWA 1HOVA 4WKIA 5BOYA 1D5JA 1C7KA 1FLSA 3LQBA 1KAPP 4WK7A 2JSDA 2RJPA 2K9CA 3EHYA 1Q3AA 5BPAA 3LKAA 4JA1A 2O36A 2X3BA 5D3CA 1MMBA 2X3AA 2MZIA 2V4BA 5I43A 1KBCA 1JAPA 1BKCA 2RJQA 1A85A 5CUHA 5I2ZA 2DDFA 1XURA 4G0DA 3F1AA 1KUKA 1BUDA 5I12A 1A86A 3LILA 4L7AA 5BOTA 3F15A 5D1UA 3DTIA 5B5OA 1MNCA 1D8FA 3U1RA 1JAQA 1CGEA 4DV8A 3Q2HA 5I0LA 3P24A 5D7WA 1SLMA 1HY7A 3OHOA 2A8HA 4WZVA 1EAKA 4G9LA 3TT4A 1L6JA 2OW9A 1GE6A 1Y0VA 4WF6A 3ZXHA 2OW2A 1ATLA 2D1NA 1SLNA 2KRJA 4PKRA 1GKCA 3DTKA 4JIJA 1GXDA 3EDGA 3LJGA 3L0TA 1EB6A 1CAQA 3AYKA 2OY2A 1QJIA 3RTTA 1SMPA 1CGFA 4ON1A 1C8TA 3B92A 3F18A 1FM1A 2USNA 1K7QA 1QIAA 1GKDA 1WNIA 4H3XA 1CQRA 3HY9A 5D1TA 4XM7A 3LJTA 1OM6A 5D2BA 5I3MA 1KUIA 4I03A 4JP4A 2W14A 3HY7A 3B8ZA 4WKEA 1HFSA 1UEAA 1YOUA 1D7XA 3EDIA 1RMZA 2FV5A 2OXWA 1EUBA 3DSLA 1BQQM 2OW1A 4H82A 1C3IA 3ELMA 4DPEA 3DPEA 3UVCA 1G12A 1OO9A 1CIZA 1B8YA 1ZVXA 2E2DA 3CKIA 3EHXA 1BZSA 1O0TA 1SATA 3LMCA 2WOAA 1J7NA 1QICA 4GR3A 3DPFA 3USNA 1HTDA 4H84A 3O64A 3ZUKA 2WO8A 1XFZA 4PKSA 456CA 1FBLA 1JANA 4DD8A 2MZEA 4H49A 3V96B 1Z3JA 1SRPA 4GWNA 3EDZA 2DDYA 830CA 4GR0A 3ZVSA 1YQYA 1XUDA 1QUAA 1IACA 4FU4A 3DL1A 1Y93A 4FXQA 3NX7A 1BKCI 3LEAA 1AF0A 3E8RA 3I7GA 2WO9A 1UMTA 3LIRA 2D1OA 1QIBA 3DNGA 3RTSA 2DW0A 3HDBA 4GF1A 4R3VA 3VTGA 3OHLA 2TCLA 1PWVA 4GUYA 4H2EA 4L63A 2E3XA 2FV9A 2POJA 1I73A 1UTTA 3TSKA 1HFCA 2MLSA 2YUFA 4EFSA 2XS3A 1OS2A 3HYGA 2QPJA 3KECA 1PWUA 2Y6DA 1JIZA 4AIGA 3LUMA 3LJZA 2OXZA 1Y8JA 4HX3A 1JAOA 3I7IA 1MMPA 1XFWA 1S4BP 4PKQA 1ZS0A 1UMSA 3HB2P 4GR8A 1ZXCA 5D1SA 2MLRA 1AKLA 1YCMA 3LE9A 4ZR5A 1IAGA 1BUVM 3TVCA 4XM6A 3KWVC 1CK7A 4A7BA 3TS4A 4JPAA 1ZTQA 5I4OA 3WV3A 4PKTA 1B3DA 1D8MA 1IAEA 1PWQA 2OXUA 3KEKA 3F19A 4I35A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AUO A;  4H1Q A;  4XBH A;  2OW0 A;  3KRY A;  2N8R A;  3L0V A;  2OY4 A;  2CKI A;  1USN A;  2DW1 A;  5JMY A;  3N2V A;  1XUC A;  3LK8 A;  4HMA A;  2YB9 A;  4IN9 A;  3MA2 A;  3F16 A;  1RM8 A;  3EDH A;  2X7M A;  1ZXV A;  1GE5 A;  1MMQ A;  3HBV P;  4L6T A;  4L19 A;  5CXA A;  4FVL A;  1CGL A;  4Q1L A;  3AIG A;  1PWP A;  3Q2G A;  1ND1 A;  2K2G A;  2X3C A;  3BA0 A;  3KMC A;  1K7I A;  1JKY A;  2I47 A;  1I76 A;  4JQG A;  5H8X A;  4J4M A;  1R54 A;  1GO7 P;  2MZH A;  5CZM A;  2L0R A;  1OM8 A;  2JT6 A;  2SRT A;  1R1I A;  2ERP A;  2AIG P;  1UTZ A;  2DW2 A;  2OVX A;  3WV1 A;  4QKZ A;  1GO8 P;  3VI1 A;  3KEJ A;  1G49 A;  1PWW A;  2JIH A;  2ERQ A;  3SHI A;  3DWB A;  1BIW A;  1R1J A;  1G9K A;  1H71 P;  1KUG A;  2J0T A;  1OM7 A;  2ERO A;  1XFX A;  3LGP A;  1G4K A;  2JNP A;  1IAA A;  2JT5 A;  4H30 A;  1YP1 A;  1DMT A;  1CXV A;  3HBU P;  3KME A;  3KHI A;  4H76 A;  4XCT A;  3HDA P;  2W15 A;  1AYK A;  5LAB A;  1KUH A;  4XM8 A;  1GE7 A;  2W12 A;  2W0D A;  1OMJ A;  4FXY P;  1AST A;  4PKV A;  1ZP5 A;  4AXQ A;  2Y6C A;  4PKU A;  5L7F A;  2OVZ A;  3K7N A;  3AYU A;  3LUN A;  2OI0 A;  1BQO A;  4GWM A;  1MMR A;  4IJO A;  1IAB A;  2HU6 A;  1BKC E;  2AYK A;  2OZR A;  4PKW A;  1I1I P;  5B5P A;  1BSW A;  1K7G A;  1G05 A;  2O3E A;  1OS9 A;  3LQ0 A;  4DF9 A;  2PJT A;  1JJ9 A;  3B2Z A;  3O2X A;  2W13 A;  1XFY A;  1XFU A;  5L79 A;  3G5C A;  4AYK A;  2CLT A;  2Z2D A;  2XS4 A;  1R1H A;  3N2U A;  1SU3 A;  1JH1 A;  3EWJ A;  1R55 A;  1DTH A;  4ILW D;  1JK3 A;  3WV2 A;  1HV5 A;  3F17 A;  3P1V A;  1JIW P;  1KUF A;  1O0Q A;  1XFV A;  1BM6 A;  4GQL A;  2YIG A;  3K7L A;  3G42 A;  4CTH A;  2J83 A;  1QJJ A;  3GBO A;  1IAD A;  3LIK A;  4A3W A;  966C A;  1ROS A;  4IUW A;  1HOV A;  4WKI A;  5BOY A;  1D5J A;  1C7K A;  1FLS A;  3LQB A;  1KAP P;  4WK7 A;  2JSD A;  2RJP A;  2K9C A;  3EHY A;  1Q3A A;  5BPA A;  3LKA A;  4JA1 A;  2O36 A;  2X3B A;  5D3C A;  1MMB A;  2X3A A;  2MZI A;  2V4B A;  5I43 A;  1KBC A;  1JAP A;  1BKC A;  2RJQ A;  1A85 A;  5CUH A;  5I2Z A;  2DDF A;  1XUR A;  4G0D A;  3F1A A;  1KUK A;  1BUD A;  5I12 A;  1A86 A;  3LIL A;  5BOT A;  3F15 A;  5D1U A;  5B5O A;  1MNC A;  1D8F A;  3U1R A;  1JAQ A;  1CGE A;  4DV8 A;  3Q2H A;  5I0L A;  3P24 A;  5D7W A;  1SLM A;  1HY7 A;  3OHO A;  2A8H A;  4WZV A;  1EAK A;  4G9L A;  3TT4 A;  1L6J A;  2OW9 A;  1GE6 A;  1Y0V A;  4WF6 A;  3ZXH A;  2OW2 A;  1ATL A;  2D1N A;  1SLN A;  2KRJ A;  4PKR A;  1GKC A;  4JIJ A;  1GXD A;  3EDG A;  3LJG A;  3L0T A;  1EB6 A;  1CAQ A;  3AYK A;  2OY2 A;  1QJI A;  3RTT A;  1SMP A;  1CGF A;  4ON1 A;  1C8T A;  3B92 A;  3F18 A;  1FM1 A;  2USN A;  1K7Q A;  1QIA A;  1GKD A;  1WNI A;  4H3X A;  1CQR A;  3HY9 A;  5D1T A;  4XM7 A;  3LJT A;  1OM6 A;  5D2B A;  5I3M A;  1KUI A;  4I03 A;  4JP4 A;  2W14 A;  3HY7 A;  3B8Z A;  4WKE A;  1HFS A;  1UEA A;  1YOU A;  1D7X A;  3EDI A;  1RMZ A;  2FV5 A;  2OXW A;  1EUB A;  3DSL A;  1BQQ M;  2OW1 A;  4H82 A;  1C3I A;  3ELM A;  4DPE A;  3DPE A;  3UVC A;  1G12 A;  1OO9 A;  1CIZ A;  1B8Y A;  1ZVX A;  2E2D A;  3CKI A;  3EHX A;  1BZS A;  1O0T A;  1SAT A;  3LMC A;  2WOA A;  1J7N A;  1QIC A;  4GR3 A;  3DPF A;  3USN A;  1HTD A;  4H84 A;  3O64 A;  3ZUK A;  2WO8 A;  1XFZ A;  4PKS A;  456C A;  1FBL A;  1JAN A;  4DD8 A;  2MZE A;  4H49 A;  3V96 B;  1Z3J A;  1SRP A;  4GWN A;  3EDZ A;  2DDY A;  830C A;  4GR0 A;  3ZVS A;  1YQY A;  1XUD A;  1QUA A;  1IAC A;  4FU4 A;  3DL1 A;  1Y93 A;  4FXQ A;  3NX7 A;  1BKC I;  3LEA A;  1AF0 A;  3E8R A;  3I7G A;  2WO9 A;  1UMT A;  3LIR A;  2D1O A;  1QIB A;  3DNG A;  3RTS A;  2DW0 A;  3HDB A;  4GF1 A;  4R3V A;  3VTG A;  3OHL A;  2TCL A;  1PWV A;  4GUY A;  4H2E A;  4L63 A;  2E3X A;  2FV9 A;  2POJ A;  1I73 A;  1UTT A;  3TSK A;  1HFC A;  2MLS A;  4EFS A;  2XS3 A;  1OS2 A;  3HYG A;  2QPJ A;  3KEC A;  1PWU A;  2Y6D A;  1JIZ A;  4AIG A;  3LUM A;  3LJZ A;  2OXZ A;  1Y8J A;  4HX3 A;  1JAO A;  3I7I A;  1MMP A;  1XFW A;  1S4B P;  4PKQ A;  1ZS0 A;  1UMS A;  3HB2 P;  4GR8 A;  1ZXC A;  5D1S A;  2MLR A;  1AKL A;  1YCM A;  3LE9 A;  4ZR5 A;  1IAG A;  1BUV M;  3TVC A;  4XM6 A;  3KWV C;  1CK7 A;  4A7B A;  3TS4 A;  4JPA A;  1ZTQ A;  5I4O A;  3WV3 A;  4PKT A;  1B3D A;  1D8M A;  1IAE A;  1PWQ A;  2OXU A;  3KEK A;  3F19 A;  4I35 A; 
#chains in the Genus database with same CATH topology
 4AUO A;  4H1Q A;  4XBH A;  2OW0 A;  3KRY A;  2N8R A;  3DTE A;  3L0V A;  2OY4 A;  2CKI A;  1USN A;  2DW1 A;  5JMY A;  3N2V A;  1XUC A;  3LK8 A;  4HMA A;  2YB9 A;  4IN9 A;  3MA2 A;  3F16 A;  1RM8 A;  3EDH A;  2X7M A;  1ZXV A;  1GE5 A;  1MMQ A;  3HBV P;  4L6T A;  4L19 A;  5CXA A;  4FVL A;  1CGL A;  4Q1L A;  3AIG A;  1PWP A;  3Q2G A;  1ND1 A;  2K2G A;  2X3C A;  3BA0 A;  3KMC A;  1K7I A;  1JKY A;  2I47 A;  1I76 A;  4JQG A;  5H8X A;  4J4M A;  1R54 A;  1GO7 P;  2MZH A;  5CZM A;  2L0R A;  1OM8 A;  2JT6 A;  2SRT A;  1R1I A;  1TVI A;  2ERP A;  2AIG P;  1UTZ A;  2DW2 A;  2OVX A;  3WV1 A;  4QKZ A;  1GO8 P;  3VI1 A;  3KEJ A;  1G49 A;  1PWW A;  2JIH A;  2ERQ A;  3SHI A;  3DWB A;  1BIW A;  1R1J A;  1G9K A;  1H71 P;  1KUG A;  2J0T A;  1OM7 A;  2ERO A;  1XFX A;  3LGP A;  1G4K A;  2JNP A;  1IAA A;  2JT5 A;  4H30 A;  1XM5 A;  1YP1 A;  1DMT A;  1CXV A;  3HBU P;  3KME A;  3KHI A;  4H76 A;  4XCT A;  3HDA P;  2W15 A;  1AYK A;  5LAB A;  1KUH A;  4XM8 A;  1GE7 A;  2W12 A;  2W0D A;  1OMJ A;  4FXY P;  1AST A;  4PKV A;  1ZP5 A;  4AXQ A;  2Y6C A;  4PKU A;  5L7F A;  2OVZ A;  3K7N A;  3AYU A;  3LUN A;  2OI0 A;  1BQO A;  4GWM A;  1MMR A;  4IJO A;  1IAB A;  2HU6 A;  1BKC E;  2AYK A;  2OZR A;  4PKW A;  1I1I P;  5B5P A;  1BSW A;  1K7G A;  1G05 A;  2O3E A;  1OS9 A;  3LQ0 A;  4DF9 A;  2PJT A;  1JJ9 A;  3B2Z A;  3O2X A;  2W13 A;  1XFY A;  1XFU A;  5L79 A;  3G5C A;  4AYK A;  2CLT A;  2Z2D A;  2XS4 A;  1R1H A;  3N2U A;  1SU3 A;  1JH1 A;  3EWJ A;  1R55 A;  1DTH A;  4ILW D;  1JK3 A;  3WV2 A;  1HV5 A;  3F17 A;  3P1V A;  1JIW P;  1KUF A;  1O0Q A;  1XFV A;  1BM6 A;  4GQL A;  2YIG A;  3K7L A;  3G42 A;  4CTH A;  2J83 A;  1QJJ A;  3GBO A;  1IAD A;  3LIK A;  4A3W A;  966C A;  1ROS A;  4IUW A;  1HOV A;  4WKI A;  5BOY A;  1D5J A;  1C7K A;  1FLS A;  3LQB A;  1KAP P;  4WK7 A;  2JSD A;  2RJP A;  2K9C A;  3EHY A;  1Q3A A;  5BPA A;  3LKA A;  4JA1 A;  2O36 A;  2X3B A;  5D3C A;  1MMB A;  2X3A A;  2MZI A;  2V4B A;  5I43 A;  1KBC A;  1JAP A;  1BKC A;  2RJQ A;  1A85 A;  5CUH A;  5I2Z A;  2DDF A;  1XUR A;  4G0D A;  3F1A A;  1KUK A;  1BUD A;  5I12 A;  1A86 A;  3LIL A;  4L7A A;  5BOT A;  3F15 A;  5D1U A;  3DTI A;  5B5O A;  1MNC A;  1D8F A;  3U1R A;  1JAQ A;  1CGE A;  4DV8 A;  3Q2H A;  5I0L A;  3P24 A;  5D7W A;  1SLM A;  1HY7 A;  3OHO A;  2A8H A;  4WZV A;  1EAK A;  4G9L A;  3TT4 A;  1L6J A;  2OW9 A;  1GE6 A;  1Y0V A;  4WF6 A;  3ZXH A;  2OW2 A;  1ATL A;  2D1N A;  1SLN A;  2KRJ A;  4PKR A;  1GKC A;  3DTK A;  4JIJ A;  1GXD A;  3EDG A;  3LJG A;  3L0T A;  1EB6 A;  1CAQ A;  3AYK A;  2OY2 A;  1QJI A;  3RTT A;  1SMP A;  1CGF A;  4ON1 A;  1C8T A;  3B92 A;  3F18 A;  1FM1 A;  2USN A;  1K7Q A;  1QIA A;  1GKD A;  1WNI A;  4H3X A;  1CQR A;  3HY9 A;  5D1T A;  4XM7 A;  3LJT A;  1OM6 A;  5D2B A;  5I3M A;  1KUI A;  4I03 A;  4JP4 A;  2W14 A;  3HY7 A;  3B8Z A;  4WKE A;  1HFS A;  1UEA A;  1YOU A;  1D7X A;  3EDI A;  1RMZ A;  2FV5 A;  2OXW A;  1EUB A;  3DSL A;  1BQQ M;  2OW1 A;  4H82 A;  1C3I A;  3ELM A;  4DPE A;  3DPE A;  3UVC A;  1G12 A;  1OO9 A;  1CIZ A;  1B8Y A;  1ZVX A;  2E2D A;  3CKI A;  3EHX A;  1BZS A;  1O0T A;  1SAT A;  3LMC A;  2WOA A;  1J7N A;  1QIC A;  4GR3 A;  3DPF A;  3USN A;  1HTD A;  4H84 A;  3O64 A;  3ZUK A;  2WO8 A;  1XFZ A;  4PKS A;  456C A;  1FBL A;  1JAN A;  4DD8 A;  2MZE A;  4H49 A;  3V96 B;  1Z3J A;  1SRP A;  4GWN A;  3EDZ A;  2DDY A;  830C A;  4GR0 A;  3ZVS A;  1YQY A;  1XUD A;  1QUA A;  1IAC A;  4FU4 A;  3DL1 A;  1Y93 A;  4FXQ A;  3NX7 A;  1BKC I;  3LEA A;  1AF0 A;  3E8R A;  3I7G A;  2WO9 A;  1UMT A;  3LIR A;  2D1O A;  1QIB A;  3DNG A;  3RTS A;  2DW0 A;  3HDB A;  4GF1 A;  4R3V A;  3VTG A;  3OHL A;  2TCL A;  1PWV A;  1XAX A;  4GUY A;  4H2E A;  4L63 A;  2E3X A;  2FV9 A;  2POJ A;  1I73 A;  1UTT A;  3TSK A;  1HFC A;  2MLS A;  2YUF A;  4EFS A;  2XS3 A;  1OS2 A;  3HYG A;  2QPJ A;  1OZ9 A;  3KEC A;  1PWU A;  2Y6D A;  1JIZ A;  4AIG A;  3LUM A;  3LJZ A;  2OXZ A;  1Y8J A;  4HX3 A;  1JAO A;  3I7I A;  1MMP A;  1XFW A;  1S4B P;  4PKQ A;  1ZS0 A;  1UMS A;  3HB2 P;  4GR8 A;  1ZXC A;  5D1S A;  2MLR A;  1AKL A;  1YCM A;  3LE9 A;  4ZR5 A;  1IAG A;  1BUV M;  3TVC A;  4XM6 A;  3KWV C;  1CK7 A;  4A7B A;  3TS4 A;  4JPA A;  1ZTQ A;  5I4O A;  3WV3 A;  4PKT A;  1B3D A;  1D8M A;  1IAE A;  1PWQ A;  2OXU A;  3KEK A;  3F19 A;  4I35 A; 
#chains in the Genus database with same CATH homology
 4AUO A;  4H1Q A;  4XBH A;  2OW0 A;  3KRY A;  2N8R A;  3DTE A;  3L0V A;  2OY4 A;  2CKI A;  1USN A;  2DW1 A;  5JMY A;  3N2V A;  1XUC A;  3LK8 A;  4HMA A;  2YB9 A;  4IN9 A;  3MA2 A;  3F16 A;  1RM8 A;  3EDH A;  2X7M A;  1ZXV A;  1GE5 A;  1MMQ A;  3HBV P;  4L6T A;  4L19 A;  5CXA A;  4FVL A;  1CGL A;  4Q1L A;  3AIG A;  1PWP A;  3Q2G A;  1ND1 A;  2K2G A;  2X3C A;  3BA0 A;  3KMC A;  1K7I A;  1JKY A;  2I47 A;  1I76 A;  4JQG A;  5H8X A;  4J4M A;  1R54 A;  1GO7 P;  2MZH A;  5CZM A;  2L0R A;  1OM8 A;  2JT6 A;  2SRT A;  1R1I A;  2ERP A;  2AIG P;  1UTZ A;  2DW2 A;  2OVX A;  3WV1 A;  4QKZ A;  1GO8 P;  3VI1 A;  3KEJ A;  1G49 A;  1PWW A;  2JIH A;  2ERQ A;  3SHI A;  3DWB A;  1BIW A;  1R1J A;  1G9K A;  1H71 P;  1KUG A;  2J0T A;  1OM7 A;  2ERO A;  1XFX A;  3LGP A;  1G4K A;  2JNP A;  1IAA A;  2JT5 A;  4H30 A;  1YP1 A;  1DMT A;  1CXV A;  3HBU P;  3KME A;  3KHI A;  4H76 A;  4XCT A;  3HDA P;  2W15 A;  1AYK A;  5LAB A;  1KUH A;  4XM8 A;  1GE7 A;  2W12 A;  2W0D A;  1OMJ A;  4FXY P;  1AST A;  4PKV A;  1ZP5 A;  4AXQ A;  2Y6C A;  4PKU A;  5L7F A;  2OVZ A;  3K7N A;  3AYU A;  3LUN A;  2OI0 A;  1BQO A;  4GWM A;  1MMR A;  4IJO A;  1IAB A;  2HU6 A;  1BKC E;  2AYK A;  2OZR A;  4PKW A;  1I1I P;  5B5P A;  1BSW A;  1K7G A;  1G05 A;  2O3E A;  1OS9 A;  3LQ0 A;  4DF9 A;  2PJT A;  1JJ9 A;  3B2Z A;  3O2X A;  2W13 A;  1XFY A;  1XFU A;  5L79 A;  3G5C A;  4AYK A;  2CLT A;  2Z2D A;  2XS4 A;  1R1H A;  3N2U A;  1SU3 A;  1JH1 A;  3EWJ A;  1R55 A;  1DTH A;  4ILW D;  1JK3 A;  3WV2 A;  1HV5 A;  3F17 A;  3P1V A;  1JIW P;  1KUF A;  1O0Q A;  1XFV A;  1BM6 A;  4GQL A;  2YIG A;  3K7L A;  3G42 A;  4CTH A;  2J83 A;  1QJJ A;  3GBO A;  1IAD A;  3LIK A;  4A3W A;  966C A;  1ROS A;  4IUW A;  1HOV A;  4WKI A;  5BOY A;  1D5J A;  1C7K A;  1FLS A;  3LQB A;  1KAP P;  4WK7 A;  2JSD A;  2RJP A;  2K9C A;  3EHY A;  1Q3A A;  5BPA A;  3LKA A;  4JA1 A;  2O36 A;  2X3B A;  5D3C A;  1MMB A;  2X3A A;  2MZI A;  2V4B A;  5I43 A;  1KBC A;  1JAP A;  1BKC A;  2RJQ A;  1A85 A;  5CUH A;  5I2Z A;  2DDF A;  1XUR A;  4G0D A;  3F1A A;  1KUK A;  1BUD A;  5I12 A;  1A86 A;  3LIL A;  4L7A A;  5BOT A;  3F15 A;  5D1U A;  3DTI A;  5B5O A;  1MNC A;  1D8F A;  3U1R A;  1JAQ A;  1CGE A;  4DV8 A;  3Q2H A;  5I0L A;  3P24 A;  5D7W A;  1SLM A;  1HY7 A;  3OHO A;  2A8H A;  4WZV A;  1EAK A;  4G9L A;  3TT4 A;  1L6J A;  2OW9 A;  1GE6 A;  1Y0V A;  4WF6 A;  3ZXH A;  2OW2 A;  1ATL A;  2D1N A;  1SLN A;  2KRJ A;  4PKR A;  1GKC A;  3DTK A;  4JIJ A;  1GXD A;  3EDG A;  3LJG A;  3L0T A;  1EB6 A;  1CAQ A;  3AYK A;  2OY2 A;  1QJI A;  3RTT A;  1SMP A;  1CGF A;  4ON1 A;  1C8T A;  3B92 A;  3F18 A;  1FM1 A;  2USN A;  1K7Q A;  1QIA A;  1GKD A;  1WNI A;  4H3X A;  1CQR A;  3HY9 A;  5D1T A;  4XM7 A;  3LJT A;  1OM6 A;  5D2B A;  5I3M A;  1KUI A;  4I03 A;  4JP4 A;  2W14 A;  3HY7 A;  3B8Z A;  4WKE A;  1HFS A;  1UEA A;  1YOU A;  1D7X A;  3EDI A;  1RMZ A;  2FV5 A;  2OXW A;  1EUB A;  3DSL A;  1BQQ M;  2OW1 A;  4H82 A;  1C3I A;  3ELM A;  4DPE A;  3DPE A;  3UVC A;  1G12 A;  1OO9 A;  1CIZ A;  1B8Y A;  1ZVX A;  2E2D A;  3CKI A;  3EHX A;  1BZS A;  1O0T A;  1SAT A;  3LMC A;  2WOA A;  1J7N A;  1QIC A;  4GR3 A;  3DPF A;  3USN A;  1HTD A;  4H84 A;  3O64 A;  3ZUK A;  2WO8 A;  1XFZ A;  4PKS A;  456C A;  1FBL A;  1JAN A;  4DD8 A;  2MZE A;  4H49 A;  3V96 B;  1Z3J A;  1SRP A;  4GWN A;  3EDZ A;  2DDY A;  830C A;  4GR0 A;  3ZVS A;  1YQY A;  1XUD A;  1QUA A;  1IAC A;  4FU4 A;  3DL1 A;  1Y93 A;  4FXQ A;  3NX7 A;  1BKC I;  3LEA A;  1AF0 A;  3E8R A;  3I7G A;  2WO9 A;  1UMT A;  3LIR A;  2D1O A;  1QIB A;  3DNG A;  3RTS A;  2DW0 A;  3HDB A;  4GF1 A;  4R3V A;  3VTG A;  3OHL A;  2TCL A;  1PWV A;  4GUY A;  4H2E A;  4L63 A;  2E3X A;  2FV9 A;  2POJ A;  1I73 A;  1UTT A;  3TSK A;  1HFC A;  2MLS A;  2YUF A;  4EFS A;  2XS3 A;  1OS2 A;  3HYG A;  2QPJ A;  3KEC A;  1PWU A;  2Y6D A;  1JIZ A;  4AIG A;  3LUM A;  3LJZ A;  2OXZ A;  1Y8J A;  4HX3 A;  1JAO A;  3I7I A;  1MMP A;  1XFW A;  1S4B P;  4PKQ A;  1ZS0 A;  1UMS A;  3HB2 P;  4GR8 A;  1ZXC A;  5D1S A;  2MLR A;  1AKL A;  1YCM A;  3LE9 A;  4ZR5 A;  1IAG A;  1BUV M;  3TVC A;  4XM6 A;  3KWV C;  1CK7 A;  4A7B A;  3TS4 A;  4JPA A;  1ZTQ A;  5I4O A;  3WV3 A;  4PKT A;  1B3D A;  1D8M A;  1IAE A;  1PWQ A;  2OXU A;  3KEK A;  3F19 A;  4I35 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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