1ZXCA

Crystal structure of catalytic domain of tnf-alpha converting enzyme (tace) with inhibitor
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
259
structure length
259
Chain Sequence
DPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords ADAM 17
publication title Acetylenic TACE inhibitors. Part 2: SAR of six-membered cyclic sulfonamide hydroxamates.
pubmed doi rcsb
source organism Homo sapiens
total genus 87
structure length 259
sequence length 259
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2005-06-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1zxcA00
3WV1A 4EFSA 5L79A 1XFYA 2L0RA 2Z2DA 4XM7A 5CXAA 2OVZA 4L6TA 4AUOA 3GBOA 1I76A 1C8TA 3RTTA 3EDGA 4PKRA 5CZMA 3ZXHA 3EHXA 1HV5A 4PKUA 3EDHA 2E3XA 3I7GA 1YQYA 1JAOA 3AYKA 1IAAA 3OHOA 5I3MA 4JIJA 1KUGA 2CKIA 1GKCA 1XFZA 1D8FA 1PWQA 1CGEA 3USNA 1USNA 4PKWA 1SATA 1DMTA 2OXZA 1K7GA 2ERPA 5I0LA 5LABA 5B5OA 1EAKA 2E2DA 3F17A 5D3CA 2FV9A 1Y8JA 2OVXA 1OS9A 2J83A 1OO9A 1EUBA 4IUWA 3ELMA 2W15A 2MLSA 1EB6A 3BA0A 1BUVM 1CXVA 4J4MA 2V4BA 1I1IP 3I7IA 3N2UA 3HBVP 3CKIA 2JNPA 1H71P 3KECA 5L7FA 4H1QA 4DD8A 3UVCA 4H76A 1CGLA 2X3BA 4A3WA 1G05A 1S4BP 3EDIA 1BZSA 4PKVA 1ROSA 3AYUA 1QIBA 4JA1A 4DPEA 2YIGA 1G4KA 4IJOA 1KUIA 1MMQA 1KBCA 1CIZA 1G12A 3HDAP 1BKCI 5D7WA 5H8XA 2Y6DA 1MMPA 2HU6A 4FXYP 1D5JA 2WO8A 1CK7A 4GR3A 1KUFA 3KEJA 3LKAA 3ZVSA 1YCMA 1SRPA 1ZS0A 1SU3A 4DV8A 5CUHA 5B5PA 1OM7A 2CLTA 1O0TA 456CA 2DW2A 2X3CA 3LUMA 1QICA 1R1IA 1B3DA 2OY2A 2EROA 1YOUA 3DSLA 4DF9A 1JAPA 1ASTA 2POJA 1ZXVA 3LQBA 1OM8A 4XBHA 4PKQA 3OHLA 3TT4A 1BSWA 3SHIA 1GE6A 1SLMA 4HMAA 1A86A 2FV5A 1Y93A 4G0DA 4GWMA 3LILA 4H30A 1GXDA 4GWNA 3LMCA 4WK7A 1IACA 4WKEA 3O2XA 4ZR5A 2MZIA 2XS4A 3KMEA 2N8RA 3HY7A 3F18A 3EDZA 1PWWA 4WKIA 4H2EA 4L63A 2QPJA 1K7IA 1J7NA 2AIGP 1JKYA 1JIZA 3KMCA 4JP4A 1QUAA 2OI0A 2I47A 1QJJA 3B8ZA 3MA2A 1UMSA 2XS3A 2K2GA 1Q3AA 1O0QA 1GO7P 3RTSA 1RM8A 4HX3A 3DNGA 3KHIA 1L6JA 5D1UA 1XUDA 1GE5A 3AIGA 3KEKA 3N2VA 4H3XA 3V96B 1R1JA 2DDFA 3TS4A 1BKCA 2WOAA 3WV2A 3L0TA 2D1NA 1D7XA 1G9KA 3VTGA 2KRJA 3B92A 2PJTA 4ON1A 3LJTA 5D2BA 3P24A 4WF6A 1ND1A 2JIHA 3HY9A 1IAGA 2Y6CA 4XM6A 2X3AA 3ZUKA 4GR8A 3F16A 2D1OA 2MLRA 1KUHA 4GR0A 3L0VA 3LIKA 1MMRA 1IADA 1QJIA 2W0DA 2USNA 1GE7A 3LUNA 4H84A 1ZXCA 2K9CA 1FM1A 2OXWA 3EWJA 4IN9A 2DW0A 3F15A 1XURA 1XFVA 2OW9A 1SLNA 4QKZA 1Z3JA 2SRTA 3F19A 1BKCE 5I12A 1WNIA 4ILWD 1FBLA 1HY7A 1K7QA 3F1AA 1OMJA 4A7BA 3HDBA 1XUCA 4FXQA 2OW0A 3P1VA 3HYGA 3HB2P 5JMYA 3VI1A 1R54A 1DTHA 1RMZA 1R55A 3K7NA 3LQ0A 3K7LA 2WO9A 2RJPA 2W14A 2YB9A 1SMPA 830CA 1G49A 2X7MA 4L19A 3KRYA 4FU4A 3LJZA 4I35A 4R3VA 4H82A 2JT5A 3KWVC 1BQOA 1BQQM 2DDYA 2JSDA 1C7KA 4I03A 1ZVXA 1JAQA 3G42A 3NX7A 4JPAA 1XFXA 2TCLA 1IAEA 1JH1A 4GUYA 2ERQA 2OZRA 3U1RA 3LK8A 1HTDA 4GQLA 2A8HA 4AIGA 2AYKA 1IABA 1BUDA 1UEAA 1I73A 1GO8P 1CQRA 1KAPP 4H49A 1CAQA 2OY4A 4WZVA 966CA 4JQGA 1PWPA 1D8MA 5I43A 4XM8A 3Q2HA 1UTTA 2DW1A 3Q2GA 3TSKA 1UMTA 2W12A 1HOVA 1PWVA 1C3IA 3HBUP 1ATLA 1HFSA 2J0TA 3LE9A 3LGPA 1A85A 3B2ZA 3TVCA 2MZHA 2O3EA 3G5CA 1XFWA 3LJGA 1OM6A 3EHYA 1BIWA 1BM6A 3O64A 1MNCA 2W13A 1QIAA 1AF0A 1HFCA 1JANA 1CGFA 4Q1LA 1FLSA 5BOTA 1JJ9A 4G9LA 4AXQA 4PKSA 5I2ZA 1MMBA 4FVLA 3DPEA 1ZP5A 1ZTQA 2MZEA 3LIRA 4GF1A 2OW1A 5BOYA 1JK3A 1JIWP 3DL1A 1PWUA 4AYKA 1GKDA 1AKLA 3WV3A 5I4OA 4XCTA 2OXUA 2JT6A 3DPFA 3LEAA 4PKTA 5D1TA 4CTHA 1KUKA 1UTZA 1B8YA 1OS2A 3DWBA 2RJQA 3E8RA 1AYKA 5D1SA 1R1HA 1Y0VA 1XFUA 2OW2A 1YP1A 5BPAA 2O36A
chains in the Genus database with same CATH superfamily
3WV1A 4EFSA 5L79A 1XFYA 2L0RA 2Z2DA 4XM7A 5CXAA 2OVZA 4L6TA 4AUOA 3GBOA 1I76A 1C8TA 3RTTA 3EDGA 4PKRA 5CZMA 3ZXHA 3EHXA 1HV5A 4PKUA 3EDHA 2E3XA 3I7GA 1YQYA 4L7AA 1JAOA 3AYKA 1IAAA 3OHOA 5I3MA 4JIJA 1KUGA 2CKIA 1GKCA 1XFZA 1D8FA 1PWQA 1CGEA 3USNA 1USNA 4PKWA 1SATA 1DMTA 2OXZA 1K7GA 2ERPA 5I0LA 5LABA 5B5OA 1EAKA 2E2DA 3F17A 5D3CA 2FV9A 1Y8JA 2OVXA 1OS9A 2J83A 1OO9A 1EUBA 4IUWA 3ELMA 2W15A 2MLSA 1EB6A 3BA0A 1BUVM 1CXVA 4J4MA 2V4BA 1I1IP 3I7IA 3N2UA 3HBVP 3CKIA 2JNPA 1H71P 3KECA 5L7FA 4H1QA 4DD8A 3UVCA 4H76A 1CGLA 2X3BA 4A3WA 1G05A 1S4BP 3EDIA 1BZSA 4PKVA 1ROSA 3AYUA 1QIBA 2YUFA 4JA1A 4DPEA 2YIGA 1G4KA 4IJOA 1KUIA 1MMQA 1KBCA 1CIZA 1G12A 3HDAP 1BKCI 5D7WA 5H8XA 2Y6DA 1MMPA 2HU6A 4FXYP 1D5JA 2WO8A 1CK7A 4GR3A 1KUFA 3KEJA 3LKAA 3ZVSA 1YCMA 1SRPA 1ZS0A 1SU3A 4DV8A 5CUHA 5B5PA 1OM7A 2CLTA 1O0TA 456CA 2DW2A 2X3CA 3LUMA 1TVIA 1QICA 1R1IA 1B3DA 2OY2A 2EROA 1YOUA 3DSLA 4DF9A 1JAPA 1ASTA 2POJA 1ZXVA 3LQBA 1OM8A 4XBHA 4PKQA 3OHLA 3TT4A 1BSWA 3SHIA 1GE6A 1SLMA 4HMAA 1A86A 2FV5A 1Y93A 4G0DA 4GWMA 3LILA 4H30A 1GXDA 4GWNA 3LMCA 4WK7A 1IACA 4WKEA 3O2XA 4ZR5A 2MZIA 2XS4A 3KMEA 2N8RA 3HY7A 3F18A 3EDZA 1PWWA 4WKIA 4H2EA 4L63A 2QPJA 1K7IA 1J7NA 2AIGP 1JKYA 1JIZA 3KMCA 4JP4A 1QUAA 2OI0A 2I47A 3DTEA 1QJJA 3B8ZA 3MA2A 1UMSA 1OZ9A 2XS3A 2K2GA 1Q3AA 3DTKA 1O0QA 1GO7P 3RTSA 1RM8A 4HX3A 3DNGA 3KHIA 1L6JA 5D1UA 1XUDA 1GE5A 3AIGA 3KEKA 3N2VA 4H3XA 3V96B 1R1JA 2DDFA 3TS4A 1BKCA 2WOAA 3WV2A 3L0TA 2D1NA 1D7XA 1G9KA 3VTGA 2KRJA 3B92A 2PJTA 4ON1A 3LJTA 5D2BA 3P24A 4WF6A 1ND1A 2JIHA 3HY9A 1IAGA 2Y6CA 4XM6A 2X3AA 3ZUKA 4GR8A 3F16A 2D1OA 2MLRA 1KUHA 4GR0A 3L0VA 3LIKA 1MMRA 1IADA 1QJIA 2W0DA 2USNA 1GE7A 3LUNA 4H84A 1ZXCA 2K9CA 1FM1A 2OXWA 3EWJA 4IN9A 2DW0A 3F15A 1XURA 1XFVA 2OW9A 1SLNA 4QKZA 1Z3JA 2SRTA 3F19A 1BKCE 5I12A 1WNIA 4ILWD 1FBLA 1HY7A 1K7QA 3F1AA 1OMJA 4A7BA 3HDBA 1XUCA 4FXQA 2OW0A 3P1VA 3HYGA 3HB2P 5JMYA 3VI1A 1R54A 1DTHA 1RMZA 1R55A 3K7NA 3LQ0A 3K7LA 2WO9A 2RJPA 2W14A 2YB9A 1SMPA 830CA 1G49A 2X7MA 4L19A 3KRYA 4FU4A 3LJZA 4I35A 4R3VA 4H82A 2JT5A 3KWVC 1BQOA 1BQQM 2DDYA 2JSDA 1C7KA 4I03A 1ZVXA 1JAQA 3G42A 3NX7A 4JPAA 1XFXA 2TCLA 1IAEA 1JH1A 4GUYA 2ERQA 2OZRA 3U1RA 3LK8A 1HTDA 4GQLA 2A8HA 4AIGA 2AYKA 1IABA 1BUDA 1UEAA 1I73A 1GO8P 1CQRA 1KAPP 4H49A 1CAQA 2OY4A 1XAXA 4WZVA 966CA 4JQGA 1PWPA 1D8MA 5I43A 4XM8A 3Q2HA 1UTTA 2DW1A 3Q2GA 3TSKA 1UMTA 2W12A 1HOVA 1PWVA 1C3IA 3HBUP 1ATLA 1HFSA 2J0TA 3DTIA 3LE9A 3LGPA 1A85A 3B2ZA 3TVCA 2MZHA 2O3EA 3G5CA 1XFWA 3LJGA 1OM6A 3EHYA 1BIWA 1XM5A 1BM6A 3O64A 1MNCA 2W13A 1QIAA 1AF0A 1HFCA 1JANA 1CGFA 4Q1LA 1FLSA 5BOTA 1JJ9A 4G9LA 4AXQA 4PKSA 5I2ZA 1MMBA 4FVLA 3DPEA 1ZP5A 1ZTQA 2MZEA 3LIRA 4GF1A 2OW1A 5BOYA 1JK3A 1JIWP 3DL1A 1PWUA 4AYKA 1GKDA 1AKLA 3WV3A 5I4OA 4XCTA 2OXUA 2JT6A 3DPFA 3LEAA 4PKTA 5D1TA 4CTHA 1KUKA 1UTZA 1B8YA 1OS2A 3DWBA 2RJQA 3E8RA 1AYKA 5D1SA 1R1HA 1Y0VA 1XFUA 2OW2A 1YP1A 5BPAA 2O36A
chains in the Genus database with same CATH topology
3WV1A 4EFSA 5L79A 1XFYA 2L0RA 2Z2DA 4XM7A 5CXAA 2OVZA 4L6TA 4AUOA 3GBOA 1I76A 1C8TA 3RTTA 3EDGA 4PKRA 5CZMA 3ZXHA 3EHXA 1HV5A 4PKUA 3EDHA 2E3XA 3I7GA 1YQYA 4L7AA 1JAOA 3AYKA 1IAAA 3OHOA 5I3MA 4JIJA 1KUGA 2CKIA 1GKCA 1XFZA 1D8FA 1PWQA 1CGEA 3USNA 1USNA 4PKWA 1SATA 1DMTA 2OXZA 1K7GA 2ERPA 5I0LA 5LABA 5B5OA 1EAKA 2E2DA 3F17A 5D3CA 2FV9A 1Y8JA 2OVXA 1OS9A 2J83A 1OO9A 1EUBA 4IUWA 3ELMA 2W15A 2MLSA 1EB6A 3BA0A 1BUVM 1CXVA 4J4MA 2V4BA 1I1IP 3I7IA 3N2UA 3HBVP 3CKIA 2JNPA 1H71P 3KECA 5L7FA 4H1QA 4DD8A 3UVCA 4H76A 1CGLA 2X3BA 4A3WA 1G05A 1S4BP 3EDIA 1BZSA 4PKVA 1ROSA 3AYUA 1QIBA 2YUFA 4JA1A 4DPEA 2YIGA 1G4KA 4IJOA 1KUIA 1MMQA 1KBCA 1CIZA 1G12A 3HDAP 1BKCI 5D7WA 5H8XA 2Y6DA 1MMPA 2HU6A 4FXYP 1D5JA 2WO8A 1CK7A 4GR3A 1KUFA 3KEJA 3LKAA 3ZVSA 1YCMA 1SRPA 1ZS0A 1SU3A 4DV8A 5CUHA 5B5PA 1OM7A 2CLTA 1O0TA 456CA 2DW2A 2X3CA 3LUMA 1QICA 1R1IA 1B3DA 2OY2A 2EROA 1YOUA 3DSLA 4DF9A 1JAPA 1ASTA 2POJA 1ZXVA 3LQBA 1OM8A 4XBHA 4PKQA 3OHLA 3TT4A 1BSWA 3SHIA 1GE6A 1SLMA 4HMAA 1A86A 2FV5A 1Y93A 4G0DA 4GWMA 3LILA 4H30A 1GXDA 4GWNA 3LMCA 4WK7A 1IACA 4WKEA 3O2XA 4ZR5A 2MZIA 2XS4A 3KMEA 2N8RA 3HY7A 3F18A 3EDZA 1PWWA 4WKIA 4H2EA 4L63A 2QPJA 1K7IA 1J7NA 2AIGP 1JKYA 1JIZA 3KMCA 4JP4A 1QUAA 2OI0A 2I47A 3DTEA 1QJJA 3B8ZA 3MA2A 1UMSA 2XS3A 2K2GA 1Q3AA 3DTKA 1O0QA 1GO7P 3RTSA 1RM8A 4HX3A 3DNGA 3KHIA 1L6JA 5D1UA 1XUDA 1GE5A 3AIGA 3KEKA 3N2VA 4H3XA 3V96B 1R1JA 2DDFA 3TS4A 1BKCA 2WOAA 3WV2A 3L0TA 2D1NA 1D7XA 1G9KA 3VTGA 2KRJA 3B92A 2PJTA 4ON1A 3LJTA 5D2BA 3P24A 4WF6A 1ND1A 2JIHA 3HY9A 1IAGA 2Y6CA 4XM6A 2X3AA 3ZUKA 4GR8A 3F16A 2D1OA 2MLRA 1KUHA 4GR0A 3L0VA 3LIKA 1MMRA 1IADA 1QJIA 2W0DA 2USNA 1GE7A 3LUNA 4H84A 1ZXCA 2K9CA 1FM1A 2OXWA 3EWJA 4IN9A 2DW0A 3F15A 1XURA 1XFVA 2OW9A 1SLNA 4QKZA 1Z3JA 2SRTA 3F19A 1BKCE 5I12A 1WNIA 4ILWD 1FBLA 1HY7A 1K7QA 3F1AA 1OMJA 4A7BA 3HDBA 1XUCA 4FXQA 2OW0A 3P1VA 3HYGA 3HB2P 5JMYA 3VI1A 1R54A 1DTHA 1RMZA 1R55A 3K7NA 3LQ0A 3K7LA 2WO9A 2RJPA 2W14A 2YB9A 1SMPA 830CA 1G49A 2X7MA 4L19A 3KRYA 4FU4A 3LJZA 4I35A 4R3VA 4H82A 2JT5A 3KWVC 1BQOA 1BQQM 2DDYA 2JSDA 1C7KA 4I03A 1ZVXA 1JAQA 3G42A 3NX7A 4JPAA 1XFXA 2TCLA 1IAEA 1JH1A 4GUYA 2ERQA 2OZRA 3U1RA 3LK8A 1HTDA 4GQLA 2A8HA 4AIGA 2AYKA 1IABA 1BUDA 1UEAA 1I73A 1GO8P 1CQRA 1KAPP 4H49A 1CAQA 2OY4A 4WZVA 966CA 4JQGA 1PWPA 1D8MA 5I43A 4XM8A 3Q2HA 1UTTA 2DW1A 3Q2GA 3TSKA 1UMTA 2W12A 1HOVA 1PWVA 1C3IA 3HBUP 1ATLA 1HFSA 2J0TA 3DTIA 3LE9A 3LGPA 1A85A 3B2ZA 3TVCA 2MZHA 2O3EA 3G5CA 1XFWA 3LJGA 1OM6A 3EHYA 1BIWA 1BM6A 3O64A 1MNCA 2W13A 1QIAA 1AF0A 1HFCA 1JANA 1CGFA 4Q1LA 1FLSA 5BOTA 1JJ9A 4G9LA 4AXQA 4PKSA 5I2ZA 1MMBA 4FVLA 3DPEA 1ZP5A 1ZTQA 2MZEA 3LIRA 4GF1A 2OW1A 5BOYA 1JK3A 1JIWP 3DL1A 1PWUA 4AYKA 1GKDA 1AKLA 3WV3A 5I4OA 4XCTA 2OXUA 2JT6A 3DPFA 3LEAA 4PKTA 5D1TA 4CTHA 1KUKA 1UTZA 1B8YA 1OS2A 3DWBA 2RJQA 3E8RA 1AYKA 5D1SA 1R1HA 1Y0VA 1XFUA 2OW2A 1YP1A 5BPAA 2O36A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WV1 A;  4EFS A;  5L79 A;  1XFY A;  2L0R A;  2Z2D A;  4XM7 A;  5CXA A;  2OVZ A;  4L6T A;  4AUO A;  3GBO A;  1I76 A;  1C8T A;  3RTT A;  3EDG A;  4PKR A;  5CZM A;  3ZXH A;  3EHX A;  1HV5 A;  4PKU A;  3EDH A;  2E3X A;  3I7G A;  1YQY A;  1JAO A;  3AYK A;  1IAA A;  3OHO A;  5I3M A;  4JIJ A;  1KUG A;  2CKI A;  1GKC A;  1XFZ A;  1D8F A;  1PWQ A;  1CGE A;  3USN A;  1USN A;  4PKW A;  1SAT A;  1DMT A;  2OXZ A;  1K7G A;  2ERP A;  5I0L A;  5LAB A;  5B5O A;  1EAK A;  2E2D A;  3F17 A;  5D3C A;  2FV9 A;  1Y8J A;  2OVX A;  1OS9 A;  2J83 A;  1OO9 A;  1EUB A;  4IUW A;  3ELM A;  2W15 A;  2MLS A;  1EB6 A;  3BA0 A;  1BUV M;  1CXV A;  4J4M A;  2V4B A;  1I1I P;  3I7I A;  3N2U A;  3HBV P;  3CKI A;  2JNP A;  1H71 P;  3KEC A;  5L7F A;  4H1Q A;  4DD8 A;  3UVC A;  4H76 A;  1CGL A;  2X3B A;  4A3W A;  1G05 A;  1S4B P;  3EDI A;  1BZS A;  4PKV A;  1ROS A;  3AYU A;  1QIB A;  4JA1 A;  4DPE A;  2YIG A;  1G4K A;  4IJO A;  1KUI A;  1MMQ A;  1KBC A;  1CIZ A;  1G12 A;  3HDA P;  1BKC I;  5D7W A;  5H8X A;  2Y6D A;  1MMP A;  2HU6 A;  4FXY P;  1D5J A;  2WO8 A;  1CK7 A;  4GR3 A;  1KUF A;  3KEJ A;  3LKA A;  3ZVS A;  1YCM A;  1SRP A;  1ZS0 A;  1SU3 A;  4DV8 A;  5CUH A;  5B5P A;  1OM7 A;  2CLT A;  1O0T A;  456C A;  2DW2 A;  2X3C A;  3LUM A;  1QIC A;  1R1I A;  1B3D A;  2OY2 A;  2ERO A;  1YOU A;  3DSL A;  4DF9 A;  1JAP A;  1AST A;  2POJ A;  1ZXV A;  3LQB A;  1OM8 A;  4XBH A;  4PKQ A;  3OHL A;  3TT4 A;  1BSW A;  3SHI A;  1GE6 A;  1SLM A;  4HMA A;  1A86 A;  2FV5 A;  1Y93 A;  4G0D A;  4GWM A;  3LIL A;  4H30 A;  1GXD A;  4GWN A;  3LMC A;  4WK7 A;  1IAC A;  4WKE A;  3O2X A;  4ZR5 A;  2MZI A;  2XS4 A;  3KME A;  2N8R A;  3HY7 A;  3F18 A;  3EDZ A;  1PWW A;  4WKI A;  4H2E A;  4L63 A;  2QPJ A;  1K7I A;  1J7N A;  2AIG P;  1JKY A;  1JIZ A;  3KMC A;  4JP4 A;  1QUA A;  2OI0 A;  2I47 A;  1QJJ A;  3B8Z A;  3MA2 A;  1UMS A;  2XS3 A;  2K2G A;  1Q3A A;  1O0Q A;  1GO7 P;  3RTS A;  1RM8 A;  4HX3 A;  3DNG A;  3KHI A;  1L6J A;  5D1U A;  1XUD A;  1GE5 A;  3AIG A;  3KEK A;  3N2V A;  4H3X A;  3V96 B;  1R1J A;  2DDF A;  3TS4 A;  1BKC A;  2WOA A;  3WV2 A;  3L0T A;  2D1N A;  1D7X A;  1G9K A;  3VTG A;  2KRJ A;  3B92 A;  2PJT A;  4ON1 A;  3LJT A;  5D2B A;  3P24 A;  4WF6 A;  1ND1 A;  2JIH A;  3HY9 A;  1IAG A;  2Y6C A;  4XM6 A;  2X3A A;  3ZUK A;  4GR8 A;  3F16 A;  2D1O A;  2MLR A;  1KUH A;  4GR0 A;  3L0V A;  3LIK A;  1MMR A;  1IAD A;  1QJI A;  2W0D A;  2USN A;  1GE7 A;  3LUN A;  4H84 A;  1ZXC A;  2K9C A;  1FM1 A;  2OXW A;  3EWJ A;  4IN9 A;  2DW0 A;  3F15 A;  1XUR A;  1XFV A;  2OW9 A;  1SLN A;  4QKZ A;  1Z3J A;  2SRT A;  3F19 A;  1BKC E;  5I12 A;  1WNI A;  4ILW D;  1FBL A;  1HY7 A;  1K7Q A;  3F1A A;  1OMJ A;  4A7B A;  3HDB A;  1XUC A;  4FXQ A;  2OW0 A;  3P1V A;  3HYG A;  3HB2 P;  5JMY A;  3VI1 A;  1R54 A;  1DTH A;  1RMZ A;  1R55 A;  3K7N A;  3LQ0 A;  3K7L A;  2WO9 A;  2RJP A;  2W14 A;  2YB9 A;  1SMP A;  830C A;  1G49 A;  2X7M A;  4L19 A;  3KRY A;  4FU4 A;  3LJZ A;  4I35 A;  4R3V A;  4H82 A;  2JT5 A;  3KWV C;  1BQO A;  1BQQ M;  2DDY A;  2JSD A;  1C7K A;  4I03 A;  1ZVX A;  1JAQ A;  3G42 A;  3NX7 A;  4JPA A;  1XFX A;  2TCL A;  1IAE A;  1JH1 A;  4GUY A;  2ERQ A;  2OZR A;  3U1R A;  3LK8 A;  1HTD A;  4GQL A;  2A8H A;  4AIG A;  2AYK A;  1IAB A;  1BUD A;  1UEA A;  1I73 A;  1GO8 P;  1CQR A;  1KAP P;  4H49 A;  1CAQ A;  2OY4 A;  4WZV A;  966C A;  4JQG A;  1PWP A;  1D8M A;  5I43 A;  4XM8 A;  3Q2H A;  1UTT A;  2DW1 A;  3Q2G A;  3TSK A;  1UMT A;  2W12 A;  1HOV A;  1PWV A;  1C3I A;  3HBU P;  1ATL A;  1HFS A;  2J0T A;  3LE9 A;  3LGP A;  1A85 A;  3B2Z A;  3TVC A;  2MZH A;  2O3E A;  3G5C A;  1XFW A;  3LJG A;  1OM6 A;  3EHY A;  1BIW A;  1BM6 A;  3O64 A;  1MNC A;  2W13 A;  1QIA A;  1AF0 A;  1HFC A;  1JAN A;  1CGF A;  4Q1L A;  1FLS A;  5BOT A;  1JJ9 A;  4G9L A;  4AXQ A;  4PKS A;  5I2Z A;  1MMB A;  4FVL A;  3DPE A;  1ZP5 A;  1ZTQ A;  2MZE A;  3LIR A;  4GF1 A;  2OW1 A;  5BOY A;  1JK3 A;  1JIW P;  3DL1 A;  1PWU A;  4AYK A;  1GKD A;  1AKL A;  3WV3 A;  5I4O A;  4XCT A;  2OXU A;  2JT6 A;  3DPF A;  3LEA A;  4PKT A;  5D1T A;  4CTH A;  1KUK A;  1UTZ A;  1B8Y A;  1OS2 A;  3DWB A;  2RJQ A;  3E8R A;  1AYK A;  5D1S A;  1R1H A;  1Y0V A;  1XFU A;  2OW2 A;  1YP1 A;  5BPA A;  2O36 A; 
#chains in the Genus database with same CATH topology
 3WV1 A;  4EFS A;  5L79 A;  1XFY A;  2L0R A;  2Z2D A;  4XM7 A;  5CXA A;  2OVZ A;  4L6T A;  4AUO A;  3GBO A;  1I76 A;  1C8T A;  3RTT A;  3EDG A;  4PKR A;  5CZM A;  3ZXH A;  3EHX A;  1HV5 A;  4PKU A;  3EDH A;  2E3X A;  3I7G A;  1YQY A;  4L7A A;  1JAO A;  3AYK A;  1IAA A;  3OHO A;  5I3M A;  4JIJ A;  1KUG A;  2CKI A;  1GKC A;  1XFZ A;  1D8F A;  1PWQ A;  1CGE A;  3USN A;  1USN A;  4PKW A;  1SAT A;  1DMT A;  2OXZ A;  1K7G A;  2ERP A;  5I0L A;  5LAB A;  5B5O A;  1EAK A;  2E2D A;  3F17 A;  5D3C A;  2FV9 A;  1Y8J A;  2OVX A;  1OS9 A;  2J83 A;  1OO9 A;  1EUB A;  4IUW A;  3ELM A;  2W15 A;  2MLS A;  1EB6 A;  3BA0 A;  1BUV M;  1CXV A;  4J4M A;  2V4B A;  1I1I P;  3I7I A;  3N2U A;  3HBV P;  3CKI A;  2JNP A;  1H71 P;  3KEC A;  5L7F A;  4H1Q A;  4DD8 A;  3UVC A;  4H76 A;  1CGL A;  2X3B A;  4A3W A;  1G05 A;  1S4B P;  3EDI A;  1BZS A;  4PKV A;  1ROS A;  3AYU A;  1QIB A;  2YUF A;  4JA1 A;  4DPE A;  2YIG A;  1G4K A;  4IJO A;  1KUI A;  1MMQ A;  1KBC A;  1CIZ A;  1G12 A;  3HDA P;  1BKC I;  5D7W A;  5H8X A;  2Y6D A;  1MMP A;  2HU6 A;  4FXY P;  1D5J A;  2WO8 A;  1CK7 A;  4GR3 A;  1KUF A;  3KEJ A;  3LKA A;  3ZVS A;  1YCM A;  1SRP A;  1ZS0 A;  1SU3 A;  4DV8 A;  5CUH A;  5B5P A;  1OM7 A;  2CLT A;  1O0T A;  456C A;  2DW2 A;  2X3C A;  3LUM A;  1TVI A;  1QIC A;  1R1I A;  1B3D A;  2OY2 A;  2ERO A;  1YOU A;  3DSL A;  4DF9 A;  1JAP A;  1AST A;  2POJ A;  1ZXV A;  3LQB A;  1OM8 A;  4XBH A;  4PKQ A;  3OHL A;  3TT4 A;  1BSW A;  3SHI A;  1GE6 A;  1SLM A;  4HMA A;  1A86 A;  2FV5 A;  1Y93 A;  4G0D A;  4GWM A;  3LIL A;  4H30 A;  1GXD A;  4GWN A;  3LMC A;  4WK7 A;  1IAC A;  4WKE A;  3O2X A;  4ZR5 A;  2MZI A;  2XS4 A;  3KME A;  2N8R A;  3HY7 A;  3F18 A;  3EDZ A;  1PWW A;  4WKI A;  4H2E A;  4L63 A;  2QPJ A;  1K7I A;  1J7N A;  2AIG P;  1JKY A;  1JIZ A;  3KMC A;  4JP4 A;  1QUA A;  2OI0 A;  2I47 A;  3DTE A;  1QJJ A;  3B8Z A;  3MA2 A;  1UMS A;  1OZ9 A;  2XS3 A;  2K2G A;  1Q3A A;  3DTK A;  1O0Q A;  1GO7 P;  3RTS A;  1RM8 A;  4HX3 A;  3DNG A;  3KHI A;  1L6J A;  5D1U A;  1XUD A;  1GE5 A;  3AIG A;  3KEK A;  3N2V A;  4H3X A;  3V96 B;  1R1J A;  2DDF A;  3TS4 A;  1BKC A;  2WOA A;  3WV2 A;  3L0T A;  2D1N A;  1D7X A;  1G9K A;  3VTG A;  2KRJ A;  3B92 A;  2PJT A;  4ON1 A;  3LJT A;  5D2B A;  3P24 A;  4WF6 A;  1ND1 A;  2JIH A;  3HY9 A;  1IAG A;  2Y6C A;  4XM6 A;  2X3A A;  3ZUK A;  4GR8 A;  3F16 A;  2D1O A;  2MLR A;  1KUH A;  4GR0 A;  3L0V A;  3LIK A;  1MMR A;  1IAD A;  1QJI A;  2W0D A;  2USN A;  1GE7 A;  3LUN A;  4H84 A;  1ZXC A;  2K9C A;  1FM1 A;  2OXW A;  3EWJ A;  4IN9 A;  2DW0 A;  3F15 A;  1XUR A;  1XFV A;  2OW9 A;  1SLN A;  4QKZ A;  1Z3J A;  2SRT A;  3F19 A;  1BKC E;  5I12 A;  1WNI A;  4ILW D;  1FBL A;  1HY7 A;  1K7Q A;  3F1A A;  1OMJ A;  4A7B A;  3HDB A;  1XUC A;  4FXQ A;  2OW0 A;  3P1V A;  3HYG A;  3HB2 P;  5JMY A;  3VI1 A;  1R54 A;  1DTH A;  1RMZ A;  1R55 A;  3K7N A;  3LQ0 A;  3K7L A;  2WO9 A;  2RJP A;  2W14 A;  2YB9 A;  1SMP A;  830C A;  1G49 A;  2X7M A;  4L19 A;  3KRY A;  4FU4 A;  3LJZ A;  4I35 A;  4R3V A;  4H82 A;  2JT5 A;  3KWV C;  1BQO A;  1BQQ M;  2DDY A;  2JSD A;  1C7K A;  4I03 A;  1ZVX A;  1JAQ A;  3G42 A;  3NX7 A;  4JPA A;  1XFX A;  2TCL A;  1IAE A;  1JH1 A;  4GUY A;  2ERQ A;  2OZR A;  3U1R A;  3LK8 A;  1HTD A;  4GQL A;  2A8H A;  4AIG A;  2AYK A;  1IAB A;  1BUD A;  1UEA A;  1I73 A;  1GO8 P;  1CQR A;  1KAP P;  4H49 A;  1CAQ A;  2OY4 A;  1XAX A;  4WZV A;  966C A;  4JQG A;  1PWP A;  1D8M A;  5I43 A;  4XM8 A;  3Q2H A;  1UTT A;  2DW1 A;  3Q2G A;  3TSK A;  1UMT A;  2W12 A;  1HOV A;  1PWV A;  1C3I A;  3HBU P;  1ATL A;  1HFS A;  2J0T A;  3DTI A;  3LE9 A;  3LGP A;  1A85 A;  3B2Z A;  3TVC A;  2MZH A;  2O3E A;  3G5C A;  1XFW A;  3LJG A;  1OM6 A;  3EHY A;  1BIW A;  1XM5 A;  1BM6 A;  3O64 A;  1MNC A;  2W13 A;  1QIA A;  1AF0 A;  1HFC A;  1JAN A;  1CGF A;  4Q1L A;  1FLS A;  5BOT A;  1JJ9 A;  4G9L A;  4AXQ A;  4PKS A;  5I2Z A;  1MMB A;  4FVL A;  3DPE A;  1ZP5 A;  1ZTQ A;  2MZE A;  3LIR A;  4GF1 A;  2OW1 A;  5BOY A;  1JK3 A;  1JIW P;  3DL1 A;  1PWU A;  4AYK A;  1GKD A;  1AKL A;  3WV3 A;  5I4O A;  4XCT A;  2OXU A;  2JT6 A;  3DPF A;  3LEA A;  4PKT A;  5D1T A;  4CTH A;  1KUK A;  1UTZ A;  1B8Y A;  1OS2 A;  3DWB A;  2RJQ A;  3E8R A;  1AYK A;  5D1S A;  1R1H A;  1Y0V A;  1XFU A;  2OW2 A;  1YP1 A;  5BPA A;  2O36 A; 
#chains in the Genus database with same CATH homology
 3WV1 A;  4EFS A;  5L79 A;  1XFY A;  2L0R A;  2Z2D A;  4XM7 A;  5CXA A;  2OVZ A;  4L6T A;  4AUO A;  3GBO A;  1I76 A;  1C8T A;  3RTT A;  3EDG A;  4PKR A;  5CZM A;  3ZXH A;  3EHX A;  1HV5 A;  4PKU A;  3EDH A;  2E3X A;  3I7G A;  1YQY A;  4L7A A;  1JAO A;  3AYK A;  1IAA A;  3OHO A;  5I3M A;  4JIJ A;  1KUG A;  2CKI A;  1GKC A;  1XFZ A;  1D8F A;  1PWQ A;  1CGE A;  3USN A;  1USN A;  4PKW A;  1SAT A;  1DMT A;  2OXZ A;  1K7G A;  2ERP A;  5I0L A;  5LAB A;  5B5O A;  1EAK A;  2E2D A;  3F17 A;  5D3C A;  2FV9 A;  1Y8J A;  2OVX A;  1OS9 A;  2J83 A;  1OO9 A;  1EUB A;  4IUW A;  3ELM A;  2W15 A;  2MLS A;  1EB6 A;  3BA0 A;  1BUV M;  1CXV A;  4J4M A;  2V4B A;  1I1I P;  3I7I A;  3N2U A;  3HBV P;  3CKI A;  2JNP A;  1H71 P;  3KEC A;  5L7F A;  4H1Q A;  4DD8 A;  3UVC A;  4H76 A;  1CGL A;  2X3B A;  4A3W A;  1G05 A;  1S4B P;  3EDI A;  1BZS A;  4PKV A;  1ROS A;  3AYU A;  1QIB A;  2YUF A;  4JA1 A;  4DPE A;  2YIG A;  1G4K A;  4IJO A;  1KUI A;  1MMQ A;  1KBC A;  1CIZ A;  1G12 A;  3HDA P;  1BKC I;  5D7W A;  5H8X A;  2Y6D A;  1MMP A;  2HU6 A;  4FXY P;  1D5J A;  2WO8 A;  1CK7 A;  4GR3 A;  1KUF A;  3KEJ A;  3LKA A;  3ZVS A;  1YCM A;  1SRP A;  1ZS0 A;  1SU3 A;  4DV8 A;  5CUH A;  5B5P A;  1OM7 A;  2CLT A;  1O0T A;  456C A;  2DW2 A;  2X3C A;  3LUM A;  1QIC A;  1R1I A;  1B3D A;  2OY2 A;  2ERO A;  1YOU A;  3DSL A;  4DF9 A;  1JAP A;  1AST A;  2POJ A;  1ZXV A;  3LQB A;  1OM8 A;  4XBH A;  4PKQ A;  3OHL A;  3TT4 A;  1BSW A;  3SHI A;  1GE6 A;  1SLM A;  4HMA A;  1A86 A;  2FV5 A;  1Y93 A;  4G0D A;  4GWM A;  3LIL A;  4H30 A;  1GXD A;  4GWN A;  3LMC A;  4WK7 A;  1IAC A;  4WKE A;  3O2X A;  4ZR5 A;  2MZI A;  2XS4 A;  3KME A;  2N8R A;  3HY7 A;  3F18 A;  3EDZ A;  1PWW A;  4WKI A;  4H2E A;  4L63 A;  2QPJ A;  1K7I A;  1J7N A;  2AIG P;  1JKY A;  1JIZ A;  3KMC A;  4JP4 A;  1QUA A;  2OI0 A;  2I47 A;  3DTE A;  1QJJ A;  3B8Z A;  3MA2 A;  1UMS A;  2XS3 A;  2K2G A;  1Q3A A;  3DTK A;  1O0Q A;  1GO7 P;  3RTS A;  1RM8 A;  4HX3 A;  3DNG A;  3KHI A;  1L6J A;  5D1U A;  1XUD A;  1GE5 A;  3AIG A;  3KEK A;  3N2V A;  4H3X A;  3V96 B;  1R1J A;  2DDF A;  3TS4 A;  1BKC A;  2WOA A;  3WV2 A;  3L0T A;  2D1N A;  1D7X A;  1G9K A;  3VTG A;  2KRJ A;  3B92 A;  2PJT A;  4ON1 A;  3LJT A;  5D2B A;  3P24 A;  4WF6 A;  1ND1 A;  2JIH A;  3HY9 A;  1IAG A;  2Y6C A;  4XM6 A;  2X3A A;  3ZUK A;  4GR8 A;  3F16 A;  2D1O A;  2MLR A;  1KUH A;  4GR0 A;  3L0V A;  3LIK A;  1MMR A;  1IAD A;  1QJI A;  2W0D A;  2USN A;  1GE7 A;  3LUN A;  4H84 A;  1ZXC A;  2K9C A;  1FM1 A;  2OXW A;  3EWJ A;  4IN9 A;  2DW0 A;  3F15 A;  1XUR A;  1XFV A;  2OW9 A;  1SLN A;  4QKZ A;  1Z3J A;  2SRT A;  3F19 A;  1BKC E;  5I12 A;  1WNI A;  4ILW D;  1FBL A;  1HY7 A;  1K7Q A;  3F1A A;  1OMJ A;  4A7B A;  3HDB A;  1XUC A;  4FXQ A;  2OW0 A;  3P1V A;  3HYG A;  3HB2 P;  5JMY A;  3VI1 A;  1R54 A;  1DTH A;  1RMZ A;  1R55 A;  3K7N A;  3LQ0 A;  3K7L A;  2WO9 A;  2RJP A;  2W14 A;  2YB9 A;  1SMP A;  830C A;  1G49 A;  2X7M A;  4L19 A;  3KRY A;  4FU4 A;  3LJZ A;  4I35 A;  4R3V A;  4H82 A;  2JT5 A;  3KWV C;  1BQO A;  1BQQ M;  2DDY A;  2JSD A;  1C7K A;  4I03 A;  1ZVX A;  1JAQ A;  3G42 A;  3NX7 A;  4JPA A;  1XFX A;  2TCL A;  1IAE A;  1JH1 A;  4GUY A;  2ERQ A;  2OZR A;  3U1R A;  3LK8 A;  1HTD A;  4GQL A;  2A8H A;  4AIG A;  2AYK A;  1IAB A;  1BUD A;  1UEA A;  1I73 A;  1GO8 P;  1CQR A;  1KAP P;  4H49 A;  1CAQ A;  2OY4 A;  4WZV A;  966C A;  4JQG A;  1PWP A;  1D8M A;  5I43 A;  4XM8 A;  3Q2H A;  1UTT A;  2DW1 A;  3Q2G A;  3TSK A;  1UMT A;  2W12 A;  1HOV A;  1PWV A;  1C3I A;  3HBU P;  1ATL A;  1HFS A;  2J0T A;  3DTI A;  3LE9 A;  3LGP A;  1A85 A;  3B2Z A;  3TVC A;  2MZH A;  2O3E A;  3G5C A;  1XFW A;  3LJG A;  1OM6 A;  3EHY A;  1BIW A;  1BM6 A;  3O64 A;  1MNC A;  2W13 A;  1QIA A;  1AF0 A;  1HFC A;  1JAN A;  1CGF A;  4Q1L A;  1FLS A;  5BOT A;  1JJ9 A;  4G9L A;  4AXQ A;  4PKS A;  5I2Z A;  1MMB A;  4FVL A;  3DPE A;  1ZP5 A;  1ZTQ A;  2MZE A;  3LIR A;  4GF1 A;  2OW1 A;  5BOY A;  1JK3 A;  1JIW P;  3DL1 A;  1PWU A;  4AYK A;  1GKD A;  1AKL A;  3WV3 A;  5I4O A;  4XCT A;  2OXU A;  2JT6 A;  3DPF A;  3LEA A;  4PKT A;  5D1T A;  4CTH A;  1KUK A;  1UTZ A;  1B8Y A;  1OS2 A;  3DWB A;  2RJQ A;  3E8R A;  1AYK A;  5D1S A;  1R1H A;  1Y0V A;  1XFU A;  2OW2 A;  1YP1 A;  5BPA A;  2O36 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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