3G42A

Crystal structure of tace with tryptophan sulfonamide derivative inhibitor
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
254
structure length
254
Chain Sequence
MKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords ADAM 17
publication title Synthesis and activity of tryptophan sulfonamide derivatives as novel non-hydroxamate TNF-alpha converting enzyme (TACE) inhibitors.
pubmed doi rcsb
source organism Homo sapiens
total genus 84
structure length 254
sequence length 254
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3g42A00
1QICA 2DDFA 3B2ZA 5B5OA 1KUHA 3B8ZA 1BUVM 966CA 4R3VA 2OY2A 1A85A 2X3CA 4HX3A 4PKSA 4WKEA 1MNCA 1KUKA 3DWBA 2ERQA 2W0DA 4ILWD 1OS9A 2K2GA 3LUMA 3F16A 4ON1A 4PKRA 1XUCA 1GXDA 1BKCA 1UMTA 3TVCA 4PKQA 1PWVA 1IAAA 1CGEA 3O2XA 1BZSA 1GKDA 2X3BA 2PJTA 1ROSA 3EHYA 1MMQA 1G49A 1XFXA 3EDZA 5LABA 1I73A 1J7NA 4XM8A 1GE5A 2AYKA 2L0RA 1DTHA 1SLNA 4A7BA 2KRJA 3DPEA 3MA2A 1G12A 1C8TA 3LJZA 3VTGA 3KEJA 3LIKA 1AF0A 2OY4A 1GE7A 1KBCA 3F1AA 1SRPA 1ATLA 1SMPA 3UVCA 1BKCI 1KUGA 2MLSA 1I76A 3LJGA 1BQQM 1YP1A 5B5PA 3L0TA 1RM8A 1KAPP 4GUYA 1CGLA 3Q2HA 2OXWA 2DW2A 1ASTA 1D8MA 3CKIA 1HTDA 4WF6A 1OM6A 3BA0A 3AYUA 2W13A 1AYKA 2MZEA 1BUDA 1R1JA 3F18A 3DL1A 1MMBA 1R1IA 4H76A 1ZP5A 2RJQA 3V96B 4FXYP 4EFSA 1G4KA 4JIJA 4J4MA 1G9KA 1JAPA 1IADA 1USNA 3KHIA 5D3CA 2D1NA 5BOTA 2SRTA 2CKIA 2X3AA 3OHLA 5D1SA 2TCLA 3HDAP 1PWWA 3P1VA 1O0QA 2I47A 1JKYA 2WO9A 5D1UA 2YB9A 4ZR5A 2XS3A 1K7GA 3B92A 3DNGA 1EB6A 5D2BA 2OVZA 1OM8A 5BPAA 1EUBA 1RMZA 2OW1A 1JANA 3OHOA 3TSKA 2MZHA 2OXUA 1D7XA 1QJJA 1SLMA 1IABA 1H71P 1ZTQA 1WNIA 4WZVA 3I7IA 1Z3JA 1PWPA 2HU6A 2WO8A 4JA1A 2E3XA 3HY7A 1CAQA 1GKCA 2O36A 2MZIA 1BM6A 4HMAA 2XS4A 2K9CA 3F19A 3LQ0A 3LILA 1I1IP 2EROA 3NX7A 1CQRA 3AYKA 4G9LA 1ZXVA 1JAQA 2DW0A 2OI0A 2Y6DA 4GR3A 1AKLA 1UTZA 5H8XA 3KMEA 2Y6CA 5I3MA 3TS4A 4GWMA 4IJOA 5L7FA 3EHXA 1QUAA 5CZMA 1HY7A 1HFSA 3LE9A 1QIBA 2A8HA 1D8FA 1DMTA 1R1HA 1XFWA 2ERPA 4DF9A 1K7IA 1PWUA 1HV5A 3KMCA 1BKCE 4G0DA 1OMJA 1XFYA 1FLSA 2JNPA 4XM7A 5I12A 4FU4A 3LEAA 4QKZA 4GR0A 2JT6A 4GR8A 1EAKA 2D1OA 2V4BA 3HY9A 3EDIA 1GO8P 3WV2A 4XCTA 1FM1A 3LKAA 4JP4A 4H49A 5I2ZA 1CK7A 830CA 2OW2A 1CXVA 3HDBA 3LJTA 4CTHA 1A86A 1Q3AA 1O0TA 1JIWP 1G05A 2POJA 1BIWA 1XURA 4FVLA 1IACA 4GQLA 1XFUA 1C3IA 1OM7A 3O64A 2JSDA 2OXZA 3KECA 1ZS0A 4IUWA 4PKTA 3HBUP 3Q2GA 1MMPA 5CUHA 4IN9A 1SU3A 1XFVA 2J0TA 3EDHA 2MLRA 1S4BP 4AYKA 3F15A 1D5JA 1OS2A 1GE6A 2USNA 1JAOA 4H2EA 3ELMA 2DW1A 1L6JA 2OW9A 2WOAA 1UTTA 2JIHA 4GF1A 4H82A 1FBLA 2W12A 3U1RA 1Y8JA 3G42A 2E2DA 3LIRA 3I7GA 3KEKA 2QPJA 4H84A 4PKVA 1QJIA 3ZXHA 4DD8A 3LMCA 3HBVP 3RTSA 2W14A 3RTTA 3ZUKA 1HFCA 1GO7P 1IAEA 4PKWA 3HYGA 3HB2P 5L79A 3G5CA 5D1TA 4DPEA 1UEAA 1YOUA 4FXQA 2Z2DA 4L6TA 4DV8A 3ZVSA 1HOVA 1JIZA 1CGFA 1K7QA 2DDYA 2CLTA 4L19A 3L0VA 1XFZA 5I43A 1OO9A 1QIAA 3K7NA 2RJPA 2FV9A 3EWJA 3KWVC 3N2UA 4Q1LA 1JH1A 4XBHA 3E8RA 1KUIA 1JJ9A 4AUOA 4H3XA 1B3DA 2X7MA 3EDGA 3K7LA 5I4OA 1B8YA 4JPAA 5JMYA 1ZXCA 2OVXA 4GWNA 4L63A 3USNA 4AXQA 1R54A 1XUDA 3AIGA 3TT4A 1BQOA 3VI1A 4H30A 4AIGA 3LGPA 2JT5A 1KUFA 1PWQA 3KRYA 3N2VA 2AIGP 4WK7A 3WV1A 2OW0A 2W15A 5D7WA 4WKIA 2OZRA 5CXAA 2FV5A 3WV3A 456CA 4I03A 1Y93A 5I0LA 3DPFA 5BOYA 2N8RA 2O3EA 1ZVXA 3LUNA 1UMSA 4A3WA 1Y0VA 4I35A 3GBOA 1MMRA 1YQYA 4H1QA 1C7KA 4XM6A 4PKUA 1ND1A 1BSWA 1R55A 2J83A 1SATA 3DSLA 3F17A 1YCMA 3LK8A 4JQGA 1IAGA 3P24A 2YIGA 1CIZA 1JK3A 3SHIA 3LQBA
chains in the Genus database with same CATH superfamily
1QICA 2DDFA 3B2ZA 5B5OA 1KUHA 3B8ZA 1BUVM 966CA 4R3VA 2OY2A 1A85A 2X3CA 4HX3A 4PKSA 4WKEA 1MNCA 1KUKA 3DWBA 2ERQA 2W0DA 4ILWD 1OS9A 2K2GA 3LUMA 3F16A 4ON1A 4PKRA 1XUCA 1GXDA 1BKCA 1OZ9A 1UMTA 3TVCA 4PKQA 1PWVA 1IAAA 1CGEA 3O2XA 1BZSA 1GKDA 2X3BA 2PJTA 1ROSA 3EHYA 1MMQA 1G49A 1XFXA 3EDZA 5LABA 1I73A 1J7NA 4XM8A 1GE5A 2AYKA 2L0RA 1DTHA 1SLNA 4A7BA 2KRJA 3DPEA 3MA2A 1G12A 1C8TA 3LJZA 3VTGA 3KEJA 3LIKA 1AF0A 2OY4A 1GE7A 1KBCA 3F1AA 1SRPA 1ATLA 1SMPA 3UVCA 1BKCI 1KUGA 2MLSA 1I76A 3LJGA 1BQQM 1YP1A 5B5PA 3L0TA 1RM8A 1KAPP 4GUYA 1CGLA 3Q2HA 2OXWA 2DW2A 1ASTA 1D8MA 3CKIA 1HTDA 4WF6A 1OM6A 3BA0A 4L7AA 3AYUA 2W13A 1AYKA 2MZEA 1BUDA 1R1JA 3F18A 3DL1A 1MMBA 1R1IA 4H76A 1ZP5A 2RJQA 3V96B 4FXYP 4EFSA 1G4KA 4JIJA 4J4MA 1G9KA 1JAPA 1IADA 1USNA 3KHIA 5D3CA 2D1NA 5BOTA 2SRTA 2CKIA 2X3AA 3OHLA 5D1SA 2TCLA 3HDAP 1PWWA 3P1VA 1O0QA 2I47A 1JKYA 2WO9A 5D1UA 2YB9A 4ZR5A 2XS3A 1K7GA 3B92A 3DNGA 1EB6A 5D2BA 2OVZA 1OM8A 5BPAA 1EUBA 1RMZA 2OW1A 1JANA 3OHOA 3TSKA 2MZHA 2OXUA 1D7XA 1QJJA 1SLMA 1IABA 1H71P 1ZTQA 1WNIA 4WZVA 3I7IA 1Z3JA 1PWPA 2HU6A 2WO8A 4JA1A 2E3XA 3HY7A 1CAQA 1GKCA 2O36A 2MZIA 1BM6A 4HMAA 2XS4A 2K9CA 3F19A 3LQ0A 3LILA 1I1IP 2EROA 3NX7A 1CQRA 3AYKA 4G9LA 1ZXVA 1JAQA 2DW0A 2OI0A 2Y6DA 4GR3A 1AKLA 1UTZA 5H8XA 3KMEA 2Y6CA 5I3MA 2YUFA 3TS4A 1TVIA 4GWMA 4IJOA 5L7FA 3EHXA 1QUAA 5CZMA 1HY7A 1HFSA 3LE9A 1QIBA 2A8HA 1D8FA 1DMTA 1R1HA 1XFWA 2ERPA 4DF9A 1K7IA 1PWUA 1HV5A 3KMCA 1BKCE 4G0DA 1OMJA 1XFYA 1FLSA 2JNPA 4XM7A 5I12A 4FU4A 3LEAA 4QKZA 4GR0A 2JT6A 4GR8A 1EAKA 2D1OA 2V4BA 3HY9A 3EDIA 1GO8P 3WV2A 4XCTA 1FM1A 3LKAA 4JP4A 4H49A 5I2ZA 1CK7A 830CA 2OW2A 1CXVA 3HDBA 3LJTA 1XAXA 4CTHA 1A86A 1Q3AA 1O0TA 1JIWP 1G05A 2POJA 1BIWA 1XURA 4FVLA 1IACA 4GQLA 1XFUA 1C3IA 1OM7A 3O64A 2JSDA 2OXZA 3KECA 1ZS0A 4IUWA 4PKTA 3HBUP 3Q2GA 1MMPA 5CUHA 4IN9A 1SU3A 1XFVA 2J0TA 3EDHA 2MLRA 1S4BP 4AYKA 3F15A 1D5JA 1OS2A 1GE6A 2USNA 1JAOA 4H2EA 3ELMA 2DW1A 1L6JA 2OW9A 2WOAA 1UTTA 2JIHA 3DTEA 4GF1A 4H82A 1FBLA 2W12A 3U1RA 1Y8JA 3G42A 2E2DA 3LIRA 3I7GA 3KEKA 2QPJA 4H84A 4PKVA 1QJIA 3ZXHA 4DD8A 3LMCA 3HBVP 3RTSA 2W14A 3RTTA 3ZUKA 1HFCA 1GO7P 1IAEA 4PKWA 3HYGA 3HB2P 5L79A 3G5CA 5D1TA 4DPEA 1UEAA 1YOUA 4FXQA 2Z2DA 4L6TA 4DV8A 3ZVSA 1HOVA 1JIZA 1CGFA 1K7QA 2DDYA 2CLTA 4L19A 3L0VA 1XFZA 5I43A 1OO9A 1QIAA 3K7NA 2RJPA 2FV9A 3EWJA 3KWVC 3N2UA 4Q1LA 1JH1A 4XBHA 3E8RA 1KUIA 1JJ9A 4AUOA 4H3XA 1B3DA 2X7MA 3EDGA 3K7LA 5I4OA 1B8YA 4JPAA 5JMYA 1ZXCA 2OVXA 4GWNA 4L63A 3USNA 4AXQA 1R54A 1XUDA 3AIGA 3TT4A 1BQOA 3VI1A 4H30A 4AIGA 3LGPA 2JT5A 1KUFA 1PWQA 3KRYA 3N2VA 2AIGP 4WK7A 3WV1A 2OW0A 2W15A 5D7WA 1XM5A 4WKIA 2OZRA 5CXAA 2FV5A 3WV3A 456CA 4I03A 1Y93A 5I0LA 3DPFA 5BOYA 2N8RA 2O3EA 1ZVXA 3LUNA 1UMSA 4A3WA 1Y0VA 3DTIA 4I35A 3DTKA 3GBOA 1MMRA 1YQYA 4H1QA 1C7KA 4XM6A 4PKUA 1ND1A 1BSWA 1R55A 2J83A 1SATA 3DSLA 3F17A 1YCMA 3LK8A 4JQGA 1IAGA 3P24A 2YIGA 1CIZA 1JK3A 3SHIA 3LQBA
chains in the Genus database with same CATH topology
1QICA 2DDFA 3B2ZA 5B5OA 1KUHA 3B8ZA 1BUVM 966CA 4R3VA 2OY2A 1A85A 2X3CA 4HX3A 4PKSA 4WKEA 1MNCA 1KUKA 3DWBA 2ERQA 2W0DA 4ILWD 1OS9A 2K2GA 3LUMA 3F16A 4ON1A 4PKRA 1XUCA 1GXDA 1BKCA 1UMTA 3TVCA 4PKQA 1PWVA 1IAAA 1CGEA 3O2XA 1BZSA 1GKDA 2X3BA 2PJTA 1ROSA 3EHYA 1MMQA 1G49A 1XFXA 3EDZA 5LABA 1I73A 1J7NA 4XM8A 1GE5A 2AYKA 2L0RA 1DTHA 1SLNA 4A7BA 2KRJA 3DPEA 3MA2A 1G12A 1C8TA 3LJZA 3VTGA 3KEJA 3LIKA 1AF0A 2OY4A 1GE7A 1KBCA 3F1AA 1SRPA 1ATLA 1SMPA 3UVCA 1BKCI 1KUGA 2MLSA 1I76A 3LJGA 1BQQM 1YP1A 5B5PA 3L0TA 1RM8A 1KAPP 4GUYA 1CGLA 3Q2HA 2OXWA 2DW2A 1ASTA 1D8MA 3CKIA 1HTDA 4WF6A 1OM6A 3BA0A 4L7AA 3AYUA 2W13A 1AYKA 2MZEA 1BUDA 1R1JA 3F18A 3DL1A 1MMBA 1R1IA 4H76A 1ZP5A 2RJQA 3V96B 4FXYP 4EFSA 1G4KA 4JIJA 4J4MA 1G9KA 1JAPA 1IADA 1USNA 3KHIA 5D3CA 2D1NA 5BOTA 2SRTA 2CKIA 2X3AA 3OHLA 5D1SA 2TCLA 3HDAP 1PWWA 3P1VA 1O0QA 2I47A 1JKYA 2WO9A 5D1UA 2YB9A 4ZR5A 2XS3A 1K7GA 3B92A 3DNGA 1EB6A 5D2BA 2OVZA 1OM8A 5BPAA 1EUBA 1RMZA 2OW1A 1JANA 3OHOA 3TSKA 2MZHA 2OXUA 1D7XA 1QJJA 1SLMA 1IABA 1H71P 1ZTQA 1WNIA 4WZVA 3I7IA 1Z3JA 1PWPA 2HU6A 2WO8A 4JA1A 2E3XA 3HY7A 1CAQA 1GKCA 2O36A 2MZIA 1BM6A 4HMAA 2XS4A 2K9CA 3F19A 3LQ0A 3LILA 1I1IP 2EROA 3NX7A 1CQRA 3AYKA 4G9LA 1ZXVA 1JAQA 2DW0A 2OI0A 2Y6DA 4GR3A 1AKLA 1UTZA 5H8XA 3KMEA 2Y6CA 5I3MA 2YUFA 3TS4A 4GWMA 4IJOA 5L7FA 3EHXA 1QUAA 5CZMA 1HY7A 1HFSA 3LE9A 1QIBA 2A8HA 1D8FA 1DMTA 1R1HA 1XFWA 2ERPA 4DF9A 1K7IA 1PWUA 1HV5A 3KMCA 1BKCE 4G0DA 1OMJA 1XFYA 1FLSA 2JNPA 4XM7A 5I12A 4FU4A 3LEAA 4QKZA 4GR0A 2JT6A 4GR8A 1EAKA 2D1OA 2V4BA 3HY9A 3EDIA 1GO8P 3WV2A 4XCTA 1FM1A 3LKAA 4JP4A 4H49A 5I2ZA 1CK7A 830CA 2OW2A 1CXVA 3HDBA 3LJTA 4CTHA 1A86A 1Q3AA 1O0TA 1JIWP 1G05A 2POJA 1BIWA 1XURA 4FVLA 1IACA 4GQLA 1XFUA 1C3IA 1OM7A 3O64A 2JSDA 2OXZA 3KECA 1ZS0A 4IUWA 4PKTA 3HBUP 3Q2GA 1MMPA 5CUHA 4IN9A 1SU3A 1XFVA 2J0TA 3EDHA 2MLRA 1S4BP 4AYKA 3F15A 1D5JA 1OS2A 1GE6A 2USNA 1JAOA 4H2EA 3ELMA 2DW1A 1L6JA 2OW9A 2WOAA 1UTTA 2JIHA 3DTEA 4GF1A 4H82A 1FBLA 2W12A 3U1RA 1Y8JA 3G42A 2E2DA 3LIRA 3I7GA 3KEKA 2QPJA 4H84A 4PKVA 1QJIA 3ZXHA 4DD8A 3LMCA 3HBVP 3RTSA 2W14A 3RTTA 3ZUKA 1HFCA 1GO7P 1IAEA 4PKWA 3HYGA 3HB2P 5L79A 3G5CA 5D1TA 4DPEA 1UEAA 1YOUA 4FXQA 2Z2DA 4L6TA 4DV8A 3ZVSA 1HOVA 1JIZA 1CGFA 1K7QA 2DDYA 2CLTA 4L19A 3L0VA 1XFZA 5I43A 1OO9A 1QIAA 3K7NA 2RJPA 2FV9A 3EWJA 3KWVC 3N2UA 4Q1LA 1JH1A 4XBHA 3E8RA 1KUIA 1JJ9A 4AUOA 4H3XA 1B3DA 2X7MA 3EDGA 3K7LA 5I4OA 1B8YA 4JPAA 5JMYA 1ZXCA 2OVXA 4GWNA 4L63A 3USNA 4AXQA 1R54A 1XUDA 3AIGA 3TT4A 1BQOA 3VI1A 4H30A 4AIGA 3LGPA 2JT5A 1KUFA 1PWQA 3KRYA 3N2VA 2AIGP 4WK7A 3WV1A 2OW0A 2W15A 5D7WA 4WKIA 2OZRA 5CXAA 2FV5A 3WV3A 456CA 4I03A 1Y93A 5I0LA 3DPFA 5BOYA 2N8RA 2O3EA 1ZVXA 3LUNA 1UMSA 4A3WA 1Y0VA 3DTIA 4I35A 3DTKA 3GBOA 1MMRA 1YQYA 4H1QA 1C7KA 4XM6A 4PKUA 1ND1A 1BSWA 1R55A 2J83A 1SATA 3DSLA 3F17A 1YCMA 3LK8A 4JQGA 1IAGA 3P24A 2YIGA 1CIZA 1JK3A 3SHIA 3LQBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QIC A;  2DDF A;  3B2Z A;  5B5O A;  1KUH A;  3B8Z A;  1BUV M;  966C A;  4R3V A;  2OY2 A;  1A85 A;  2X3C A;  4HX3 A;  4PKS A;  4WKE A;  1MNC A;  1KUK A;  3DWB A;  2ERQ A;  2W0D A;  4ILW D;  1OS9 A;  2K2G A;  3LUM A;  3F16 A;  4ON1 A;  4PKR A;  1XUC A;  1GXD A;  1BKC A;  1UMT A;  3TVC A;  4PKQ A;  1PWV A;  1IAA A;  1CGE A;  3O2X A;  1BZS A;  1GKD A;  2X3B A;  2PJT A;  1ROS A;  3EHY A;  1MMQ A;  1G49 A;  1XFX A;  3EDZ A;  5LAB A;  1I73 A;  1J7N A;  4XM8 A;  1GE5 A;  2AYK A;  2L0R A;  1DTH A;  1SLN A;  4A7B A;  2KRJ A;  3DPE A;  3MA2 A;  1G12 A;  1C8T A;  3LJZ A;  3VTG A;  3KEJ A;  3LIK A;  1AF0 A;  2OY4 A;  1GE7 A;  1KBC A;  3F1A A;  1SRP A;  1ATL A;  1SMP A;  3UVC A;  1BKC I;  1KUG A;  2MLS A;  1I76 A;  3LJG A;  1BQQ M;  1YP1 A;  5B5P A;  3L0T A;  1RM8 A;  1KAP P;  4GUY A;  1CGL A;  3Q2H A;  2OXW A;  2DW2 A;  1AST A;  1D8M A;  3CKI A;  1HTD A;  4WF6 A;  1OM6 A;  3BA0 A;  3AYU A;  2W13 A;  1AYK A;  2MZE A;  1BUD A;  1R1J A;  3F18 A;  3DL1 A;  1MMB A;  1R1I A;  4H76 A;  1ZP5 A;  2RJQ A;  3V96 B;  4FXY P;  4EFS A;  1G4K A;  4JIJ A;  4J4M A;  1G9K A;  1JAP A;  1IAD A;  1USN A;  3KHI A;  5D3C A;  2D1N A;  5BOT A;  2SRT A;  2CKI A;  2X3A A;  3OHL A;  5D1S A;  2TCL A;  3HDA P;  1PWW A;  3P1V A;  1O0Q A;  2I47 A;  1JKY A;  2WO9 A;  5D1U A;  2YB9 A;  4ZR5 A;  2XS3 A;  1K7G A;  3B92 A;  3DNG A;  1EB6 A;  5D2B A;  2OVZ A;  1OM8 A;  5BPA A;  1EUB A;  1RMZ A;  2OW1 A;  1JAN A;  3OHO A;  3TSK A;  2MZH A;  2OXU A;  1D7X A;  1QJJ A;  1SLM A;  1IAB A;  1H71 P;  1ZTQ A;  1WNI A;  4WZV A;  3I7I A;  1Z3J A;  1PWP A;  2HU6 A;  2WO8 A;  4JA1 A;  2E3X A;  3HY7 A;  1CAQ A;  1GKC A;  2O36 A;  2MZI A;  1BM6 A;  4HMA A;  2XS4 A;  2K9C A;  3F19 A;  3LQ0 A;  3LIL A;  1I1I P;  2ERO A;  3NX7 A;  1CQR A;  3AYK A;  4G9L A;  1ZXV A;  1JAQ A;  2DW0 A;  2OI0 A;  2Y6D A;  4GR3 A;  1AKL A;  1UTZ A;  5H8X A;  3KME A;  2Y6C A;  5I3M A;  3TS4 A;  4GWM A;  4IJO A;  5L7F A;  3EHX A;  1QUA A;  5CZM A;  1HY7 A;  1HFS A;  3LE9 A;  1QIB A;  2A8H A;  1D8F A;  1DMT A;  1R1H A;  1XFW A;  2ERP A;  4DF9 A;  1K7I A;  1PWU A;  1HV5 A;  3KMC A;  1BKC E;  4G0D A;  1OMJ A;  1XFY A;  1FLS A;  2JNP A;  4XM7 A;  5I12 A;  4FU4 A;  3LEA A;  4QKZ A;  4GR0 A;  2JT6 A;  4GR8 A;  1EAK A;  2D1O A;  2V4B A;  3HY9 A;  3EDI A;  1GO8 P;  3WV2 A;  4XCT A;  1FM1 A;  3LKA A;  4JP4 A;  4H49 A;  5I2Z A;  1CK7 A;  830C A;  2OW2 A;  1CXV A;  3HDB A;  3LJT A;  4CTH A;  1A86 A;  1Q3A A;  1O0T A;  1JIW P;  1G05 A;  2POJ A;  1BIW A;  1XUR A;  4FVL A;  1IAC A;  4GQL A;  1XFU A;  1C3I A;  1OM7 A;  3O64 A;  2JSD A;  2OXZ A;  3KEC A;  1ZS0 A;  4IUW A;  4PKT A;  3HBU P;  3Q2G A;  1MMP A;  5CUH A;  4IN9 A;  1SU3 A;  1XFV A;  2J0T A;  3EDH A;  2MLR A;  1S4B P;  4AYK A;  3F15 A;  1D5J A;  1OS2 A;  1GE6 A;  2USN A;  1JAO A;  4H2E A;  3ELM A;  2DW1 A;  1L6J A;  2OW9 A;  2WOA A;  1UTT A;  2JIH A;  4GF1 A;  4H82 A;  1FBL A;  2W12 A;  3U1R A;  1Y8J A;  3G42 A;  2E2D A;  3LIR A;  3I7G A;  3KEK A;  2QPJ A;  4H84 A;  4PKV A;  1QJI A;  3ZXH A;  4DD8 A;  3LMC A;  3HBV P;  3RTS A;  2W14 A;  3RTT A;  3ZUK A;  1HFC A;  1GO7 P;  1IAE A;  4PKW A;  3HYG A;  3HB2 P;  5L79 A;  3G5C A;  5D1T A;  4DPE A;  1UEA A;  1YOU A;  4FXQ A;  2Z2D A;  4L6T A;  4DV8 A;  3ZVS A;  1HOV A;  1JIZ A;  1CGF A;  1K7Q A;  2DDY A;  2CLT A;  4L19 A;  3L0V A;  1XFZ A;  5I43 A;  1OO9 A;  1QIA A;  3K7N A;  2RJP A;  2FV9 A;  3EWJ A;  3KWV C;  3N2U A;  4Q1L A;  1JH1 A;  4XBH A;  3E8R A;  1KUI A;  1JJ9 A;  4AUO A;  4H3X A;  1B3D A;  2X7M A;  3EDG A;  3K7L A;  5I4O A;  1B8Y A;  4JPA A;  5JMY A;  1ZXC A;  2OVX A;  4GWN A;  4L63 A;  3USN A;  4AXQ A;  1R54 A;  1XUD A;  3AIG A;  3TT4 A;  1BQO A;  3VI1 A;  4H30 A;  4AIG A;  3LGP A;  2JT5 A;  1KUF A;  1PWQ A;  3KRY A;  3N2V A;  2AIG P;  4WK7 A;  3WV1 A;  2OW0 A;  2W15 A;  5D7W A;  4WKI A;  2OZR A;  5CXA A;  2FV5 A;  3WV3 A;  456C A;  4I03 A;  1Y93 A;  5I0L A;  3DPF A;  5BOY A;  2N8R A;  2O3E A;  1ZVX A;  3LUN A;  1UMS A;  4A3W A;  1Y0V A;  4I35 A;  3GBO A;  1MMR A;  1YQY A;  4H1Q A;  1C7K A;  4XM6 A;  4PKU A;  1ND1 A;  1BSW A;  1R55 A;  2J83 A;  1SAT A;  3DSL A;  3F17 A;  1YCM A;  3LK8 A;  4JQG A;  1IAG A;  3P24 A;  2YIG A;  1CIZ A;  1JK3 A;  3SHI A;  3LQB A; 
#chains in the Genus database with same CATH topology
 1QIC A;  2DDF A;  3B2Z A;  5B5O A;  1KUH A;  3B8Z A;  1BUV M;  966C A;  4R3V A;  2OY2 A;  1A85 A;  2X3C A;  4HX3 A;  4PKS A;  4WKE A;  1MNC A;  1KUK A;  3DWB A;  2ERQ A;  2W0D A;  4ILW D;  1OS9 A;  2K2G A;  3LUM A;  3F16 A;  4ON1 A;  4PKR A;  1XUC A;  1GXD A;  1BKC A;  1OZ9 A;  1UMT A;  3TVC A;  4PKQ A;  1PWV A;  1IAA A;  1CGE A;  3O2X A;  1BZS A;  1GKD A;  2X3B A;  2PJT A;  1ROS A;  3EHY A;  1MMQ A;  1G49 A;  1XFX A;  3EDZ A;  5LAB A;  1I73 A;  1J7N A;  4XM8 A;  1GE5 A;  2AYK A;  2L0R A;  1DTH A;  1SLN A;  4A7B A;  2KRJ A;  3DPE A;  3MA2 A;  1G12 A;  1C8T A;  3LJZ A;  3VTG A;  3KEJ A;  3LIK A;  1AF0 A;  2OY4 A;  1GE7 A;  1KBC A;  3F1A A;  1SRP A;  1ATL A;  1SMP A;  3UVC A;  1BKC I;  1KUG A;  2MLS A;  1I76 A;  3LJG A;  1BQQ M;  1YP1 A;  5B5P A;  3L0T A;  1RM8 A;  1KAP P;  4GUY A;  1CGL A;  3Q2H A;  2OXW A;  2DW2 A;  1AST A;  1D8M A;  3CKI A;  1HTD A;  4WF6 A;  1OM6 A;  3BA0 A;  4L7A A;  3AYU A;  2W13 A;  1AYK A;  2MZE A;  1BUD A;  1R1J A;  3F18 A;  3DL1 A;  1MMB A;  1R1I A;  4H76 A;  1ZP5 A;  2RJQ A;  3V96 B;  4FXY P;  4EFS A;  1G4K A;  4JIJ A;  4J4M A;  1G9K A;  1JAP A;  1IAD A;  1USN A;  3KHI A;  5D3C A;  2D1N A;  5BOT A;  2SRT A;  2CKI A;  2X3A A;  3OHL A;  5D1S A;  2TCL A;  3HDA P;  1PWW A;  3P1V A;  1O0Q A;  2I47 A;  1JKY A;  2WO9 A;  5D1U A;  2YB9 A;  4ZR5 A;  2XS3 A;  1K7G A;  3B92 A;  3DNG A;  1EB6 A;  5D2B A;  2OVZ A;  1OM8 A;  5BPA A;  1EUB A;  1RMZ A;  2OW1 A;  1JAN A;  3OHO A;  3TSK A;  2MZH A;  2OXU A;  1D7X A;  1QJJ A;  1SLM A;  1IAB A;  1H71 P;  1ZTQ A;  1WNI A;  4WZV A;  3I7I A;  1Z3J A;  1PWP A;  2HU6 A;  2WO8 A;  4JA1 A;  2E3X A;  3HY7 A;  1CAQ A;  1GKC A;  2O36 A;  2MZI A;  1BM6 A;  4HMA A;  2XS4 A;  2K9C A;  3F19 A;  3LQ0 A;  3LIL A;  1I1I P;  2ERO A;  3NX7 A;  1CQR A;  3AYK A;  4G9L A;  1ZXV A;  1JAQ A;  2DW0 A;  2OI0 A;  2Y6D A;  4GR3 A;  1AKL A;  1UTZ A;  5H8X A;  3KME A;  2Y6C A;  5I3M A;  2YUF A;  3TS4 A;  1TVI A;  4GWM A;  4IJO A;  5L7F A;  3EHX A;  1QUA A;  5CZM A;  1HY7 A;  1HFS A;  3LE9 A;  1QIB A;  2A8H A;  1D8F A;  1DMT A;  1R1H A;  1XFW A;  2ERP A;  4DF9 A;  1K7I A;  1PWU A;  1HV5 A;  3KMC A;  1BKC E;  4G0D A;  1OMJ A;  1XFY A;  1FLS A;  2JNP A;  4XM7 A;  5I12 A;  4FU4 A;  3LEA A;  4QKZ A;  4GR0 A;  2JT6 A;  4GR8 A;  1EAK A;  2D1O A;  2V4B A;  3HY9 A;  3EDI A;  1GO8 P;  3WV2 A;  4XCT A;  1FM1 A;  3LKA A;  4JP4 A;  4H49 A;  5I2Z A;  1CK7 A;  830C A;  2OW2 A;  1CXV A;  3HDB A;  3LJT A;  1XAX A;  4CTH A;  1A86 A;  1Q3A A;  1O0T A;  1JIW P;  1G05 A;  2POJ A;  1BIW A;  1XUR A;  4FVL A;  1IAC A;  4GQL A;  1XFU A;  1C3I A;  1OM7 A;  3O64 A;  2JSD A;  2OXZ A;  3KEC A;  1ZS0 A;  4IUW A;  4PKT A;  3HBU P;  3Q2G A;  1MMP A;  5CUH A;  4IN9 A;  1SU3 A;  1XFV A;  2J0T A;  3EDH A;  2MLR A;  1S4B P;  4AYK A;  3F15 A;  1D5J A;  1OS2 A;  1GE6 A;  2USN A;  1JAO A;  4H2E A;  3ELM A;  2DW1 A;  1L6J A;  2OW9 A;  2WOA A;  1UTT A;  2JIH A;  3DTE A;  4GF1 A;  4H82 A;  1FBL A;  2W12 A;  3U1R A;  1Y8J A;  3G42 A;  2E2D A;  3LIR A;  3I7G A;  3KEK A;  2QPJ A;  4H84 A;  4PKV A;  1QJI A;  3ZXH A;  4DD8 A;  3LMC A;  3HBV P;  3RTS A;  2W14 A;  3RTT A;  3ZUK A;  1HFC A;  1GO7 P;  1IAE A;  4PKW A;  3HYG A;  3HB2 P;  5L79 A;  3G5C A;  5D1T A;  4DPE A;  1UEA A;  1YOU A;  4FXQ A;  2Z2D A;  4L6T A;  4DV8 A;  3ZVS A;  1HOV A;  1JIZ A;  1CGF A;  1K7Q A;  2DDY A;  2CLT A;  4L19 A;  3L0V A;  1XFZ A;  5I43 A;  1OO9 A;  1QIA A;  3K7N A;  2RJP A;  2FV9 A;  3EWJ A;  3KWV C;  3N2U A;  4Q1L A;  1JH1 A;  4XBH A;  3E8R A;  1KUI A;  1JJ9 A;  4AUO A;  4H3X A;  1B3D A;  2X7M A;  3EDG A;  3K7L A;  5I4O A;  1B8Y A;  4JPA A;  5JMY A;  1ZXC A;  2OVX A;  4GWN A;  4L63 A;  3USN A;  4AXQ A;  1R54 A;  1XUD A;  3AIG A;  3TT4 A;  1BQO A;  3VI1 A;  4H30 A;  4AIG A;  3LGP A;  2JT5 A;  1KUF A;  1PWQ A;  3KRY A;  3N2V A;  2AIG P;  4WK7 A;  3WV1 A;  2OW0 A;  2W15 A;  5D7W A;  1XM5 A;  4WKI A;  2OZR A;  5CXA A;  2FV5 A;  3WV3 A;  456C A;  4I03 A;  1Y93 A;  5I0L A;  3DPF A;  5BOY A;  2N8R A;  2O3E A;  1ZVX A;  3LUN A;  1UMS A;  4A3W A;  1Y0V A;  3DTI A;  4I35 A;  3DTK A;  3GBO A;  1MMR A;  1YQY A;  4H1Q A;  1C7K A;  4XM6 A;  4PKU A;  1ND1 A;  1BSW A;  1R55 A;  2J83 A;  1SAT A;  3DSL A;  3F17 A;  1YCM A;  3LK8 A;  4JQG A;  1IAG A;  3P24 A;  2YIG A;  1CIZ A;  1JK3 A;  3SHI A;  3LQB A; 
#chains in the Genus database with same CATH homology
 1QIC A;  2DDF A;  3B2Z A;  5B5O A;  1KUH A;  3B8Z A;  1BUV M;  966C A;  4R3V A;  2OY2 A;  1A85 A;  2X3C A;  4HX3 A;  4PKS A;  4WKE A;  1MNC A;  1KUK A;  3DWB A;  2ERQ A;  2W0D A;  4ILW D;  1OS9 A;  2K2G A;  3LUM A;  3F16 A;  4ON1 A;  4PKR A;  1XUC A;  1GXD A;  1BKC A;  1UMT A;  3TVC A;  4PKQ A;  1PWV A;  1IAA A;  1CGE A;  3O2X A;  1BZS A;  1GKD A;  2X3B A;  2PJT A;  1ROS A;  3EHY A;  1MMQ A;  1G49 A;  1XFX A;  3EDZ A;  5LAB A;  1I73 A;  1J7N A;  4XM8 A;  1GE5 A;  2AYK A;  2L0R A;  1DTH A;  1SLN A;  4A7B A;  2KRJ A;  3DPE A;  3MA2 A;  1G12 A;  1C8T A;  3LJZ A;  3VTG A;  3KEJ A;  3LIK A;  1AF0 A;  2OY4 A;  1GE7 A;  1KBC A;  3F1A A;  1SRP A;  1ATL A;  1SMP A;  3UVC A;  1BKC I;  1KUG A;  2MLS A;  1I76 A;  3LJG A;  1BQQ M;  1YP1 A;  5B5P A;  3L0T A;  1RM8 A;  1KAP P;  4GUY A;  1CGL A;  3Q2H A;  2OXW A;  2DW2 A;  1AST A;  1D8M A;  3CKI A;  1HTD A;  4WF6 A;  1OM6 A;  3BA0 A;  4L7A A;  3AYU A;  2W13 A;  1AYK A;  2MZE A;  1BUD A;  1R1J A;  3F18 A;  3DL1 A;  1MMB A;  1R1I A;  4H76 A;  1ZP5 A;  2RJQ A;  3V96 B;  4FXY P;  4EFS A;  1G4K A;  4JIJ A;  4J4M A;  1G9K A;  1JAP A;  1IAD A;  1USN A;  3KHI A;  5D3C A;  2D1N A;  5BOT A;  2SRT A;  2CKI A;  2X3A A;  3OHL A;  5D1S A;  2TCL A;  3HDA P;  1PWW A;  3P1V A;  1O0Q A;  2I47 A;  1JKY A;  2WO9 A;  5D1U A;  2YB9 A;  4ZR5 A;  2XS3 A;  1K7G A;  3B92 A;  3DNG A;  1EB6 A;  5D2B A;  2OVZ A;  1OM8 A;  5BPA A;  1EUB A;  1RMZ A;  2OW1 A;  1JAN A;  3OHO A;  3TSK A;  2MZH A;  2OXU A;  1D7X A;  1QJJ A;  1SLM A;  1IAB A;  1H71 P;  1ZTQ A;  1WNI A;  4WZV A;  3I7I A;  1Z3J A;  1PWP A;  2HU6 A;  2WO8 A;  4JA1 A;  2E3X A;  3HY7 A;  1CAQ A;  1GKC A;  2O36 A;  2MZI A;  1BM6 A;  4HMA A;  2XS4 A;  2K9C A;  3F19 A;  3LQ0 A;  3LIL A;  1I1I P;  2ERO A;  3NX7 A;  1CQR A;  3AYK A;  4G9L A;  1ZXV A;  1JAQ A;  2DW0 A;  2OI0 A;  2Y6D A;  4GR3 A;  1AKL A;  1UTZ A;  5H8X A;  3KME A;  2Y6C A;  5I3M A;  2YUF A;  3TS4 A;  4GWM A;  4IJO A;  5L7F A;  3EHX A;  1QUA A;  5CZM A;  1HY7 A;  1HFS A;  3LE9 A;  1QIB A;  2A8H A;  1D8F A;  1DMT A;  1R1H A;  1XFW A;  2ERP A;  4DF9 A;  1K7I A;  1PWU A;  1HV5 A;  3KMC A;  1BKC E;  4G0D A;  1OMJ A;  1XFY A;  1FLS A;  2JNP A;  4XM7 A;  5I12 A;  4FU4 A;  3LEA A;  4QKZ A;  4GR0 A;  2JT6 A;  4GR8 A;  1EAK A;  2D1O A;  2V4B A;  3HY9 A;  3EDI A;  1GO8 P;  3WV2 A;  4XCT A;  1FM1 A;  3LKA A;  4JP4 A;  4H49 A;  5I2Z A;  1CK7 A;  830C A;  2OW2 A;  1CXV A;  3HDB A;  3LJT A;  4CTH A;  1A86 A;  1Q3A A;  1O0T A;  1JIW P;  1G05 A;  2POJ A;  1BIW A;  1XUR A;  4FVL A;  1IAC A;  4GQL A;  1XFU A;  1C3I A;  1OM7 A;  3O64 A;  2JSD A;  2OXZ A;  3KEC A;  1ZS0 A;  4IUW A;  4PKT A;  3HBU P;  3Q2G A;  1MMP A;  5CUH A;  4IN9 A;  1SU3 A;  1XFV A;  2J0T A;  3EDH A;  2MLR A;  1S4B P;  4AYK A;  3F15 A;  1D5J A;  1OS2 A;  1GE6 A;  2USN A;  1JAO A;  4H2E A;  3ELM A;  2DW1 A;  1L6J A;  2OW9 A;  2WOA A;  1UTT A;  2JIH A;  3DTE A;  4GF1 A;  4H82 A;  1FBL A;  2W12 A;  3U1R A;  1Y8J A;  3G42 A;  2E2D A;  3LIR A;  3I7G A;  3KEK A;  2QPJ A;  4H84 A;  4PKV A;  1QJI A;  3ZXH A;  4DD8 A;  3LMC A;  3HBV P;  3RTS A;  2W14 A;  3RTT A;  3ZUK A;  1HFC A;  1GO7 P;  1IAE A;  4PKW A;  3HYG A;  3HB2 P;  5L79 A;  3G5C A;  5D1T A;  4DPE A;  1UEA A;  1YOU A;  4FXQ A;  2Z2D A;  4L6T A;  4DV8 A;  3ZVS A;  1HOV A;  1JIZ A;  1CGF A;  1K7Q A;  2DDY A;  2CLT A;  4L19 A;  3L0V A;  1XFZ A;  5I43 A;  1OO9 A;  1QIA A;  3K7N A;  2RJP A;  2FV9 A;  3EWJ A;  3KWV C;  3N2U A;  4Q1L A;  1JH1 A;  4XBH A;  3E8R A;  1KUI A;  1JJ9 A;  4AUO A;  4H3X A;  1B3D A;  2X7M A;  3EDG A;  3K7L A;  5I4O A;  1B8Y A;  4JPA A;  5JMY A;  1ZXC A;  2OVX A;  4GWN A;  4L63 A;  3USN A;  4AXQ A;  1R54 A;  1XUD A;  3AIG A;  3TT4 A;  1BQO A;  3VI1 A;  4H30 A;  4AIG A;  3LGP A;  2JT5 A;  1KUF A;  1PWQ A;  3KRY A;  3N2V A;  2AIG P;  4WK7 A;  3WV1 A;  2OW0 A;  2W15 A;  5D7W A;  4WKI A;  2OZR A;  5CXA A;  2FV5 A;  3WV3 A;  456C A;  4I03 A;  1Y93 A;  5I0L A;  3DPF A;  5BOY A;  2N8R A;  2O3E A;  1ZVX A;  3LUN A;  1UMS A;  4A3W A;  1Y0V A;  3DTI A;  4I35 A;  3DTK A;  3GBO A;  1MMR A;  1YQY A;  4H1Q A;  1C7K A;  4XM6 A;  4PKU A;  1ND1 A;  1BSW A;  1R55 A;  2J83 A;  1SAT A;  3DSL A;  3F17 A;  1YCM A;  3LK8 A;  4JQG A;  1IAG A;  3P24 A;  2YIG A;  1CIZ A;  1JK3 A;  3SHI A;  3LQB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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