2E2DA

Flexibility and variability of timp binding: x-ray structure of the complex between collagenase-3/mmp-13 and timp-2
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
165
structure length
165
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Flexibility and Variability of TIMP Binding: X-ray Structure of the Complex Between Collagenase-3/MMP-13 and TIMP-2
pubmed doi rcsb
molecule keywords Matrix metallopeptidase 13
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 48
structure length 165
sequence length 165
ec nomenclature ec 3.4.24.-:
pdb deposition date 2006-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2e2dA00
5I2ZA 5JMYA 3V96B 4H30A 1JAQA 1QJJA 1BUDA 2X3BA 1QUAA 3DWBA 1C7KA 4A3WA 2ERPA 1OS2A 4H1QA 2POJA 3KECA 1EUBA 4A7BA 3O2XA 1CXVA 1BZSA 3F15A 3LQ0A 1FLSA 1MNCA 4GR8A 1ROSA 3L0TA 3Q2HA 4H49A 1GXDA 2TCLA 1OM8A 1AF0A 1GO8P 1K7GA 1ZP5A 2JIHA 1OS9A 2JT5A 2MZIA 3LUMA 2K2GA 1KUGA 4GUYA 1HFCA 1D7XA 1UTZA 1R1JA 1HY7A 2AIGP 2DDFA 1BKCI 1ATLA 1JAOA 1OMJA 2OW0A 3TVCA 3KHIA 4L19A 1G9KA 3LIKA 3WV1A 2X3AA 1S4BP 4XBHA 966CA 3O64A 1XFXA 3DPEA 3ZUKA 3AYUA 1A85A 1H71P 2DDYA 2E2DA 1YQYA 3B92A 3P24A 1CGLA 2HU6A 1D5JA 2MLSA 4WK7A 2JSDA 1PWUA 3EHXA 3KWVC 1CIZA 3HBUP 3LQBA 1JKYA 1IAGA 4H84A 1BKCE 1MMRA 3HY7A 3DSLA 2QPJA 4JQGA 1FM1A 3U1RA 1G49A 5D7WA 2DW1A 1MMBA 2USNA 1OM7A 5BOYA 3P1VA 3G42A 3N2VA 2OY4A 2RJPA 3LE9A 1OO9A 3MA2A 1IABA 2Y6DA 5BPAA 5I3MA 5I43A 1IAEA 1Y93A 2K9CA 3LILA 4L63A 5CXAA 3WV3A 1JJ9A 2OI0A 3Q2GA 5D2BA 1J7NA 1BUVM 1ZXCA 1MMQA 1FBLA 1YCMA 1CK7A 2N8RA 3RTTA 3VTGA 3LJTA 3SHIA 3KRYA 4DV8A 1USNA 1JK3A 1K7IA 1GKDA 1RMZA 4I35A 3HY9A 1KAPP 4FXYP 3ELMA 3F19A 4AUOA 5D1TA 1KUFA 5I0LA 4XM8A 1C3IA 2W14A 1I76A 4QKZA 4IN9A 3K7LA 2OY2A 3HBVP 3HB2P 1ZVXA 4WZVA 2O3EA 1UTTA 1XFVA 3LEAA 4WF6A 3AYKA 2PJTA 3NX7A 3DNGA 4XM7A 2I47A 1ASTA 2OXUA 3EWJA 4WKEA 3BA0A 1KUHA 3F17A 5L7FA 1MMPA 2E3XA 2JT6A 5LABA 2O36A 1SATA 1CGFA 2V4BA 2W15A 4GQLA 1XUCA 4L6TA 2YB9A 3K7NA 5BOTA 3CKIA 1HOVA 1BQOA 1KBCA 3TT4A 1A86A 3DL1A 2FV5A 3EDIA 2OZRA 3WV2A 1QIAA 3F18A 3UVCA 4ZR5A 4H2EA 2FV9A 2OW1A 1R1IA 1Z3JA 2DW0A 4DD8A 2OVZA 3EHYA 3LMCA 830CA 3B2ZA 1XFUA 4EFSA 1R54A 4ILWD 2XS4A 2MZEA 4FU4A 4PKVA 4JA1A 1KUIA 4H82A 3B8ZA 1SLMA 1UMTA 2Z2DA 3TSKA 2OW2A 2WOAA 4JP4A 4JIJA 3LJZA 4H3XA 1GKCA 5D1SA 1JIZA 1Q3AA 3GBOA 1PWPA 1CQRA 1HV5A 1EB6A 1IACA 4DF9A 1KUKA 3KMEA 1ZTQA 4GR0A 1L6JA 4GF1A 2SRTA 1K7QA 2MLRA 1XFZA 1R55A 2OXWA 4XCTA 2D1OA 1AKLA 1O0QA 1G05A 2Y6CA 4PKWA 1B8YA 1GE5A 4G9LA 1YOUA 4HMAA 1YP1A 3OHOA 1XFWA 4I03A 4ON1A 1BQQM 1O0TA 1SLNA 1UEAA 2W0DA 3L0VA 5D3CA 3LGPA 4G0DA 3KMCA 2KRJA 4AYKA 1GE7A 2EROA 2D1NA 1DTHA 1JANA 2L0RA 1B3DA 5CUHA 4GWMA 1PWQA 2WO9A 1EAKA 3EDHA 2ERQA 3LJGA 4CTHA 2OXZA 3TS4A 1I73A 5H8XA 1RM8A 3F1AA 3KEJA 5D1UA 2MZHA 3KEKA 1ZS0A 2CKIA 3ZVSA 1G12A 4PKSA 1I1IP 1BIWA 2J83A 4IUWA 4PKRA 3F16A 1ND1A 3LUNA 1Y8JA 1JIWP 1BM6A 4DPEA 1SU3A 4J4MA 5I4OA 4FXQA 1HFSA 2YIGA 2JNPA 1JAPA 4Q1LA 4HX3A 1XURA 1Y0VA 2W12A 3AIGA 3RTSA 1D8MA 1GO7P 1IADA 2RJQA 1OM6A 5L79A 1C8TA 2OVXA 3G5CA 4FVLA 3HDAP 1PWVA 2X7MA 1BKCA 1DMTA 4PKQA 3HYGA 1CAQA 3LK8A 3OHLA 456CA 1UMSA 1JH1A 5B5PA 3EDGA 1G4KA 2W13A 3VI1A 5CZMA 1QICA 2DW2A 1AYKA 4IJOA 1GE6A 3I7GA 4R3VA 3N2UA 5B5OA 4GR3A 3EDZA 2A8HA 3USNA 4PKUA 1R1HA 1XUDA 4XM6A 4AIGA 1XFYA 3DPFA 1SMPA 3LKAA 4GWNA 2WO8A 3I7IA 4AXQA 3E8RA 1WNIA 3HDBA 3LIRA 1ZXVA 1CGEA 3ZXHA 1D8FA 1PWWA 2CLTA 4WKIA 2OW9A 2J0TA 1QIBA 2XS3A 4JPAA 5I12A 1IAAA 4H76A 2AYKA 1SRPA 2X3CA 1BSWA 1QJIA 1HTDA 4PKTA
chains in the Genus database with same CATH superfamily
5I2ZA 5JMYA 3V96B 4H30A 1JAQA 1QJJA 1BUDA 2X3BA 1OZ9A 1QUAA 3DWBA 1C7KA 4A3WA 2ERPA 1OS2A 4H1QA 2POJA 3KECA 1EUBA 1XAXA 4A7BA 3O2XA 1CXVA 1BZSA 3F15A 3LQ0A 1FLSA 1MNCA 4GR8A 1ROSA 3L0TA 3Q2HA 4H49A 1GXDA 2TCLA 1OM8A 1AF0A 1GO8P 1K7GA 1ZP5A 2JIHA 1OS9A 2JT5A 2MZIA 3LUMA 2K2GA 1KUGA 4GUYA 1HFCA 1D7XA 1UTZA 1R1JA 1HY7A 2AIGP 2DDFA 1BKCI 1ATLA 1JAOA 1OMJA 2OW0A 3TVCA 3KHIA 4L19A 1G9KA 3LIKA 3WV1A 2X3AA 1S4BP 3DTEA 4XBHA 966CA 3O64A 4L7AA 1XFXA 3DPEA 3ZUKA 3AYUA 1A85A 1H71P 2DDYA 2E2DA 1YQYA 3B92A 3P24A 1CGLA 2HU6A 1D5JA 2MLSA 4WK7A 2JSDA 1PWUA 3EHXA 3KWVC 1XM5A 1CIZA 3HBUP 3LQBA 1JKYA 1IAGA 4H84A 1BKCE 1MMRA 3HY7A 3DSLA 2QPJA 4JQGA 1FM1A 3U1RA 1G49A 5D7WA 2DW1A 1MMBA 2USNA 1OM7A 5BOYA 3P1VA 3G42A 3N2VA 2OY4A 2RJPA 3LE9A 1OO9A 3MA2A 1IABA 2Y6DA 5BPAA 5I3MA 5I43A 1IAEA 1Y93A 2K9CA 3LILA 4L63A 5CXAA 3WV3A 1JJ9A 2OI0A 3Q2GA 5D2BA 1J7NA 1BUVM 1ZXCA 1MMQA 1FBLA 1YCMA 1CK7A 2N8RA 3RTTA 3VTGA 2YUFA 3LJTA 3SHIA 3KRYA 4DV8A 1USNA 1JK3A 1K7IA 1GKDA 1RMZA 4I35A 3HY9A 1KAPP 4FXYP 3ELMA 3F19A 4AUOA 5D1TA 1KUFA 5I0LA 4XM8A 1C3IA 2W14A 1I76A 4QKZA 4IN9A 3K7LA 2OY2A 3HBVP 3HB2P 1ZVXA 4WZVA 2O3EA 1UTTA 1XFVA 3LEAA 4WF6A 3AYKA 2PJTA 3NX7A 3DNGA 4XM7A 2I47A 1ASTA 2OXUA 3EWJA 4WKEA 3BA0A 1KUHA 3F17A 5L7FA 1MMPA 2E3XA 2JT6A 1TVIA 5LABA 2O36A 1SATA 1CGFA 2V4BA 2W15A 4GQLA 1XUCA 4L6TA 2YB9A 3K7NA 5BOTA 3CKIA 1HOVA 1BQOA 1KBCA 3TT4A 1A86A 3DL1A 2FV5A 3DTKA 3EDIA 2OZRA 3WV2A 1QIAA 3F18A 3UVCA 4ZR5A 4H2EA 2FV9A 2OW1A 1R1IA 1Z3JA 2DW0A 4DD8A 2OVZA 3EHYA 3LMCA 830CA 3B2ZA 1XFUA 4EFSA 1R54A 4ILWD 2XS4A 2MZEA 4FU4A 4PKVA 4JA1A 1KUIA 4H82A 3B8ZA 1SLMA 1UMTA 2Z2DA 3TSKA 2OW2A 2WOAA 4JP4A 4JIJA 3LJZA 4H3XA 1GKCA 5D1SA 1JIZA 1Q3AA 3GBOA 1PWPA 1CQRA 1HV5A 1EB6A 1IACA 4DF9A 1KUKA 3DTIA 3KMEA 1ZTQA 4GR0A 1L6JA 4GF1A 2SRTA 1K7QA 2MLRA 1XFZA 1R55A 2OXWA 4XCTA 2D1OA 1AKLA 1O0QA 1G05A 2Y6CA 4PKWA 1B8YA 1GE5A 4G9LA 1YOUA 4HMAA 1YP1A 3OHOA 1XFWA 4I03A 4ON1A 1BQQM 1O0TA 1SLNA 1UEAA 2W0DA 3L0VA 5D3CA 3LGPA 4G0DA 3KMCA 2KRJA 4AYKA 1GE7A 2EROA 2D1NA 1DTHA 1JANA 2L0RA 1B3DA 5CUHA 4GWMA 1PWQA 2WO9A 1EAKA 3EDHA 2ERQA 3LJGA 4CTHA 2OXZA 3TS4A 1I73A 5H8XA 1RM8A 3F1AA 3KEJA 5D1UA 2MZHA 3KEKA 1ZS0A 2CKIA 3ZVSA 1G12A 4PKSA 1I1IP 1BIWA 2J83A 4IUWA 4PKRA 3F16A 1ND1A 3LUNA 1Y8JA 1JIWP 1BM6A 4DPEA 1SU3A 4J4MA 5I4OA 4FXQA 1HFSA 2YIGA 2JNPA 1JAPA 4Q1LA 4HX3A 1XURA 1Y0VA 2W12A 3AIGA 3RTSA 1D8MA 1GO7P 1IADA 2RJQA 1OM6A 5L79A 1C8TA 2OVXA 3G5CA 4FVLA 3HDAP 1PWVA 2X7MA 1BKCA 1DMTA 4PKQA 3HYGA 1CAQA 3LK8A 3OHLA 456CA 1UMSA 1JH1A 5B5PA 3EDGA 1G4KA 2W13A 3VI1A 5CZMA 1QICA 2DW2A 1AYKA 4IJOA 1GE6A 3I7GA 4R3VA 3N2UA 5B5OA 4GR3A 3EDZA 2A8HA 3USNA 4PKUA 1R1HA 1XUDA 4XM6A 4AIGA 1XFYA 3DPFA 1SMPA 3LKAA 4GWNA 2WO8A 3I7IA 4AXQA 3E8RA 1WNIA 3HDBA 3LIRA 1ZXVA 1CGEA 3ZXHA 1D8FA 1PWWA 2CLTA 4WKIA 2OW9A 2J0TA 1QIBA 2XS3A 4JPAA 5I12A 1IAAA 4H76A 2AYKA 1SRPA 2X3CA 1BSWA 1QJIA 1HTDA 4PKTA
chains in the Genus database with same CATH topology
5I2ZA 5JMYA 3V96B 4H30A 1JAQA 1QJJA 1BUDA 2X3BA 1QUAA 3DWBA 1C7KA 4A3WA 2ERPA 1OS2A 4H1QA 2POJA 3KECA 1EUBA 4A7BA 3O2XA 1CXVA 1BZSA 3F15A 3LQ0A 1FLSA 1MNCA 4GR8A 1ROSA 3L0TA 3Q2HA 4H49A 1GXDA 2TCLA 1OM8A 1AF0A 1GO8P 1K7GA 1ZP5A 2JIHA 1OS9A 2JT5A 2MZIA 3LUMA 2K2GA 1KUGA 4GUYA 1HFCA 1D7XA 1UTZA 1R1JA 1HY7A 2AIGP 2DDFA 1BKCI 1ATLA 1JAOA 1OMJA 2OW0A 3TVCA 3KHIA 4L19A 1G9KA 3LIKA 3WV1A 2X3AA 1S4BP 3DTEA 4XBHA 966CA 3O64A 4L7AA 1XFXA 3DPEA 3ZUKA 3AYUA 1A85A 1H71P 2DDYA 2E2DA 1YQYA 3B92A 3P24A 1CGLA 2HU6A 1D5JA 2MLSA 4WK7A 2JSDA 1PWUA 3EHXA 3KWVC 1CIZA 3HBUP 3LQBA 1JKYA 1IAGA 4H84A 1BKCE 1MMRA 3HY7A 3DSLA 2QPJA 4JQGA 1FM1A 3U1RA 1G49A 5D7WA 2DW1A 1MMBA 2USNA 1OM7A 5BOYA 3P1VA 3G42A 3N2VA 2OY4A 2RJPA 3LE9A 1OO9A 3MA2A 1IABA 2Y6DA 5BPAA 5I3MA 5I43A 1IAEA 1Y93A 2K9CA 3LILA 4L63A 5CXAA 3WV3A 1JJ9A 2OI0A 3Q2GA 5D2BA 1J7NA 1BUVM 1ZXCA 1MMQA 1FBLA 1YCMA 1CK7A 2N8RA 3RTTA 3VTGA 2YUFA 3LJTA 3SHIA 3KRYA 4DV8A 1USNA 1JK3A 1K7IA 1GKDA 1RMZA 4I35A 3HY9A 1KAPP 4FXYP 3ELMA 3F19A 4AUOA 5D1TA 1KUFA 5I0LA 4XM8A 1C3IA 2W14A 1I76A 4QKZA 4IN9A 3K7LA 2OY2A 3HBVP 3HB2P 1ZVXA 4WZVA 2O3EA 1UTTA 1XFVA 3LEAA 4WF6A 3AYKA 2PJTA 3NX7A 3DNGA 4XM7A 2I47A 1ASTA 2OXUA 3EWJA 4WKEA 3BA0A 1KUHA 3F17A 5L7FA 1MMPA 2E3XA 2JT6A 5LABA 2O36A 1SATA 1CGFA 2V4BA 2W15A 4GQLA 1XUCA 4L6TA 2YB9A 3K7NA 5BOTA 3CKIA 1HOVA 1BQOA 1KBCA 3TT4A 1A86A 3DL1A 2FV5A 3DTKA 3EDIA 2OZRA 3WV2A 1QIAA 3F18A 3UVCA 4ZR5A 4H2EA 2FV9A 2OW1A 1R1IA 1Z3JA 2DW0A 4DD8A 2OVZA 3EHYA 3LMCA 830CA 3B2ZA 1XFUA 4EFSA 1R54A 4ILWD 2XS4A 2MZEA 4FU4A 4PKVA 4JA1A 1KUIA 4H82A 3B8ZA 1SLMA 1UMTA 2Z2DA 3TSKA 2OW2A 2WOAA 4JP4A 4JIJA 3LJZA 4H3XA 1GKCA 5D1SA 1JIZA 1Q3AA 3GBOA 1PWPA 1CQRA 1HV5A 1EB6A 1IACA 4DF9A 1KUKA 3DTIA 3KMEA 1ZTQA 4GR0A 1L6JA 4GF1A 2SRTA 1K7QA 2MLRA 1XFZA 1R55A 2OXWA 4XCTA 2D1OA 1AKLA 1O0QA 1G05A 2Y6CA 4PKWA 1B8YA 1GE5A 4G9LA 1YOUA 4HMAA 1YP1A 3OHOA 1XFWA 4I03A 4ON1A 1BQQM 1O0TA 1SLNA 1UEAA 2W0DA 3L0VA 5D3CA 3LGPA 4G0DA 3KMCA 2KRJA 4AYKA 1GE7A 2EROA 2D1NA 1DTHA 1JANA 2L0RA 1B3DA 5CUHA 4GWMA 1PWQA 2WO9A 1EAKA 3EDHA 2ERQA 3LJGA 4CTHA 2OXZA 3TS4A 1I73A 5H8XA 1RM8A 3F1AA 3KEJA 5D1UA 2MZHA 3KEKA 1ZS0A 2CKIA 3ZVSA 1G12A 4PKSA 1I1IP 1BIWA 2J83A 4IUWA 4PKRA 3F16A 1ND1A 3LUNA 1Y8JA 1JIWP 1BM6A 4DPEA 1SU3A 4J4MA 5I4OA 4FXQA 1HFSA 2YIGA 2JNPA 1JAPA 4Q1LA 4HX3A 1XURA 1Y0VA 2W12A 3AIGA 3RTSA 1D8MA 1GO7P 1IADA 2RJQA 1OM6A 5L79A 1C8TA 2OVXA 3G5CA 4FVLA 3HDAP 1PWVA 2X7MA 1BKCA 1DMTA 4PKQA 3HYGA 1CAQA 3LK8A 3OHLA 456CA 1UMSA 1JH1A 5B5PA 3EDGA 1G4KA 2W13A 3VI1A 5CZMA 1QICA 2DW2A 1AYKA 4IJOA 1GE6A 3I7GA 4R3VA 3N2UA 5B5OA 4GR3A 3EDZA 2A8HA 3USNA 4PKUA 1R1HA 1XUDA 4XM6A 4AIGA 1XFYA 3DPFA 1SMPA 3LKAA 4GWNA 2WO8A 3I7IA 4AXQA 3E8RA 1WNIA 3HDBA 3LIRA 1ZXVA 1CGEA 3ZXHA 1D8FA 1PWWA 2CLTA 4WKIA 2OW9A 2J0TA 1QIBA 2XS3A 4JPAA 5I12A 1IAAA 4H76A 2AYKA 1SRPA 2X3CA 1BSWA 1QJIA 1HTDA 4PKTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I2Z A;  5JMY A;  3V96 B;  4H30 A;  1JAQ A;  1QJJ A;  1BUD A;  2X3B A;  1QUA A;  3DWB A;  1C7K A;  4A3W A;  2ERP A;  1OS2 A;  4H1Q A;  2POJ A;  3KEC A;  1EUB A;  4A7B A;  3O2X A;  1CXV A;  1BZS A;  3F15 A;  3LQ0 A;  1FLS A;  1MNC A;  4GR8 A;  1ROS A;  3L0T A;  3Q2H A;  4H49 A;  1GXD A;  2TCL A;  1OM8 A;  1AF0 A;  1GO8 P;  1K7G A;  1ZP5 A;  2JIH A;  1OS9 A;  2JT5 A;  2MZI A;  3LUM A;  2K2G A;  1KUG A;  4GUY A;  1HFC A;  1D7X A;  1UTZ A;  1R1J A;  1HY7 A;  2AIG P;  2DDF A;  1BKC I;  1ATL A;  1JAO A;  1OMJ A;  2OW0 A;  3TVC A;  3KHI A;  4L19 A;  1G9K A;  3LIK A;  3WV1 A;  2X3A A;  1S4B P;  4XBH A;  966C A;  3O64 A;  1XFX A;  3DPE A;  3ZUK A;  3AYU A;  1A85 A;  1H71 P;  2DDY A;  2E2D A;  1YQY A;  3B92 A;  3P24 A;  1CGL A;  2HU6 A;  1D5J A;  2MLS A;  4WK7 A;  2JSD A;  1PWU A;  3EHX A;  3KWV C;  1CIZ A;  3HBU P;  3LQB A;  1JKY A;  1IAG A;  4H84 A;  1BKC E;  1MMR A;  3HY7 A;  3DSL A;  2QPJ A;  4JQG A;  1FM1 A;  3U1R A;  1G49 A;  5D7W A;  2DW1 A;  1MMB A;  2USN A;  1OM7 A;  5BOY A;  3P1V A;  3G42 A;  3N2V A;  2OY4 A;  2RJP A;  3LE9 A;  1OO9 A;  3MA2 A;  1IAB A;  2Y6D A;  5BPA A;  5I3M A;  5I43 A;  1IAE A;  1Y93 A;  2K9C A;  3LIL A;  4L63 A;  5CXA A;  3WV3 A;  1JJ9 A;  2OI0 A;  3Q2G A;  5D2B A;  1J7N A;  1BUV M;  1ZXC A;  1MMQ A;  1FBL A;  1YCM A;  1CK7 A;  2N8R A;  3RTT A;  3VTG A;  3LJT A;  3SHI A;  3KRY A;  4DV8 A;  1USN A;  1JK3 A;  1K7I A;  1GKD A;  1RMZ A;  4I35 A;  3HY9 A;  1KAP P;  4FXY P;  3ELM A;  3F19 A;  4AUO A;  5D1T A;  1KUF A;  5I0L A;  4XM8 A;  1C3I A;  2W14 A;  1I76 A;  4QKZ A;  4IN9 A;  3K7L A;  2OY2 A;  3HBV P;  3HB2 P;  1ZVX A;  4WZV A;  2O3E A;  1UTT A;  1XFV A;  3LEA A;  4WF6 A;  3AYK A;  2PJT A;  3NX7 A;  3DNG A;  4XM7 A;  2I47 A;  1AST A;  2OXU A;  3EWJ A;  4WKE A;  3BA0 A;  1KUH A;  3F17 A;  5L7F A;  1MMP A;  2E3X A;  2JT6 A;  5LAB A;  2O36 A;  1SAT A;  1CGF A;  2V4B A;  2W15 A;  4GQL A;  1XUC A;  4L6T A;  2YB9 A;  3K7N A;  5BOT A;  3CKI A;  1HOV A;  1BQO A;  1KBC A;  3TT4 A;  1A86 A;  3DL1 A;  2FV5 A;  3EDI A;  2OZR A;  3WV2 A;  1QIA A;  3F18 A;  3UVC A;  4ZR5 A;  4H2E A;  2FV9 A;  2OW1 A;  1R1I A;  1Z3J A;  2DW0 A;  4DD8 A;  2OVZ A;  3EHY A;  3LMC A;  830C A;  3B2Z A;  1XFU A;  4EFS A;  1R54 A;  4ILW D;  2XS4 A;  2MZE A;  4FU4 A;  4PKV A;  4JA1 A;  1KUI A;  4H82 A;  3B8Z A;  1SLM A;  1UMT A;  2Z2D A;  3TSK A;  2OW2 A;  2WOA A;  4JP4 A;  4JIJ A;  3LJZ A;  4H3X A;  1GKC A;  5D1S A;  1JIZ A;  1Q3A A;  3GBO A;  1PWP A;  1CQR A;  1HV5 A;  1EB6 A;  1IAC A;  4DF9 A;  1KUK A;  3KME A;  1ZTQ A;  4GR0 A;  1L6J A;  4GF1 A;  2SRT A;  1K7Q A;  2MLR A;  1XFZ A;  1R55 A;  2OXW A;  4XCT A;  2D1O A;  1AKL A;  1O0Q A;  1G05 A;  2Y6C A;  4PKW A;  1B8Y A;  1GE5 A;  4G9L A;  1YOU A;  4HMA A;  1YP1 A;  3OHO A;  1XFW A;  4I03 A;  4ON1 A;  1BQQ M;  1O0T A;  1SLN A;  1UEA A;  2W0D A;  3L0V A;  5D3C A;  3LGP A;  4G0D A;  3KMC A;  2KRJ A;  4AYK A;  1GE7 A;  2ERO A;  2D1N A;  1DTH A;  1JAN A;  2L0R A;  1B3D A;  5CUH A;  4GWM A;  1PWQ A;  2WO9 A;  1EAK A;  3EDH A;  2ERQ A;  3LJG A;  4CTH A;  2OXZ A;  3TS4 A;  1I73 A;  5H8X A;  1RM8 A;  3F1A A;  3KEJ A;  5D1U A;  2MZH A;  3KEK A;  1ZS0 A;  2CKI A;  3ZVS A;  1G12 A;  4PKS A;  1I1I P;  1BIW A;  2J83 A;  4IUW A;  4PKR A;  3F16 A;  1ND1 A;  3LUN A;  1Y8J A;  1JIW P;  1BM6 A;  4DPE A;  1SU3 A;  4J4M A;  5I4O A;  4FXQ A;  1HFS A;  2YIG A;  2JNP A;  1JAP A;  4Q1L A;  4HX3 A;  1XUR A;  1Y0V A;  2W12 A;  3AIG A;  3RTS A;  1D8M A;  1GO7 P;  1IAD A;  2RJQ A;  1OM6 A;  5L79 A;  1C8T A;  2OVX A;  3G5C A;  4FVL A;  3HDA P;  1PWV A;  2X7M A;  1BKC A;  1DMT A;  4PKQ A;  3HYG A;  1CAQ A;  3LK8 A;  3OHL A;  456C A;  1UMS A;  1JH1 A;  5B5P A;  3EDG A;  1G4K A;  2W13 A;  3VI1 A;  5CZM A;  1QIC A;  2DW2 A;  1AYK A;  4IJO A;  1GE6 A;  3I7G A;  4R3V A;  3N2U A;  5B5O A;  4GR3 A;  3EDZ A;  2A8H A;  3USN A;  4PKU A;  1R1H A;  1XUD A;  4XM6 A;  4AIG A;  1XFY A;  3DPF A;  1SMP A;  3LKA A;  4GWN A;  2WO8 A;  3I7I A;  4AXQ A;  3E8R A;  1WNI A;  3HDB A;  3LIR A;  1ZXV A;  1CGE A;  3ZXH A;  1D8F A;  1PWW A;  2CLT A;  4WKI A;  2OW9 A;  2J0T A;  1QIB A;  2XS3 A;  4JPA A;  5I12 A;  1IAA A;  4H76 A;  2AYK A;  1SRP A;  2X3C A;  1BSW A;  1QJI A;  1HTD A;  4PKT A; 
#chains in the Genus database with same CATH topology
 5I2Z A;  5JMY A;  3V96 B;  4H30 A;  1JAQ A;  1QJJ A;  1BUD A;  2X3B A;  1OZ9 A;  1QUA A;  3DWB A;  1C7K A;  4A3W A;  2ERP A;  1OS2 A;  4H1Q A;  2POJ A;  3KEC A;  1EUB A;  1XAX A;  4A7B A;  3O2X A;  1CXV A;  1BZS A;  3F15 A;  3LQ0 A;  1FLS A;  1MNC A;  4GR8 A;  1ROS A;  3L0T A;  3Q2H A;  4H49 A;  1GXD A;  2TCL A;  1OM8 A;  1AF0 A;  1GO8 P;  1K7G A;  1ZP5 A;  2JIH A;  1OS9 A;  2JT5 A;  2MZI A;  3LUM A;  2K2G A;  1KUG A;  4GUY A;  1HFC A;  1D7X A;  1UTZ A;  1R1J A;  1HY7 A;  2AIG P;  2DDF A;  1BKC I;  1ATL A;  1JAO A;  1OMJ A;  2OW0 A;  3TVC A;  3KHI A;  4L19 A;  1G9K A;  3LIK A;  3WV1 A;  2X3A A;  1S4B P;  3DTE A;  4XBH A;  966C A;  3O64 A;  4L7A A;  1XFX A;  3DPE A;  3ZUK A;  3AYU A;  1A85 A;  1H71 P;  2DDY A;  2E2D A;  1YQY A;  3B92 A;  3P24 A;  1CGL A;  2HU6 A;  1D5J A;  2MLS A;  4WK7 A;  2JSD A;  1PWU A;  3EHX A;  3KWV C;  1XM5 A;  1CIZ A;  3HBU P;  3LQB A;  1JKY A;  1IAG A;  4H84 A;  1BKC E;  1MMR A;  3HY7 A;  3DSL A;  2QPJ A;  4JQG A;  1FM1 A;  3U1R A;  1G49 A;  5D7W A;  2DW1 A;  1MMB A;  2USN A;  1OM7 A;  5BOY A;  3P1V A;  3G42 A;  3N2V A;  2OY4 A;  2RJP A;  3LE9 A;  1OO9 A;  3MA2 A;  1IAB A;  2Y6D A;  5BPA A;  5I3M A;  5I43 A;  1IAE A;  1Y93 A;  2K9C A;  3LIL A;  4L63 A;  5CXA A;  3WV3 A;  1JJ9 A;  2OI0 A;  3Q2G A;  5D2B A;  1J7N A;  1BUV M;  1ZXC A;  1MMQ A;  1FBL A;  1YCM A;  1CK7 A;  2N8R A;  3RTT A;  3VTG A;  2YUF A;  3LJT A;  3SHI A;  3KRY A;  4DV8 A;  1USN A;  1JK3 A;  1K7I A;  1GKD A;  1RMZ A;  4I35 A;  3HY9 A;  1KAP P;  4FXY P;  3ELM A;  3F19 A;  4AUO A;  5D1T A;  1KUF A;  5I0L A;  4XM8 A;  1C3I A;  2W14 A;  1I76 A;  4QKZ A;  4IN9 A;  3K7L A;  2OY2 A;  3HBV P;  3HB2 P;  1ZVX A;  4WZV A;  2O3E A;  1UTT A;  1XFV A;  3LEA A;  4WF6 A;  3AYK A;  2PJT A;  3NX7 A;  3DNG A;  4XM7 A;  2I47 A;  1AST A;  2OXU A;  3EWJ A;  4WKE A;  3BA0 A;  1KUH A;  3F17 A;  5L7F A;  1MMP A;  2E3X A;  2JT6 A;  1TVI A;  5LAB A;  2O36 A;  1SAT A;  1CGF A;  2V4B A;  2W15 A;  4GQL A;  1XUC A;  4L6T A;  2YB9 A;  3K7N A;  5BOT A;  3CKI A;  1HOV A;  1BQO A;  1KBC A;  3TT4 A;  1A86 A;  3DL1 A;  2FV5 A;  3DTK A;  3EDI A;  2OZR A;  3WV2 A;  1QIA A;  3F18 A;  3UVC A;  4ZR5 A;  4H2E A;  2FV9 A;  2OW1 A;  1R1I A;  1Z3J A;  2DW0 A;  4DD8 A;  2OVZ A;  3EHY A;  3LMC A;  830C A;  3B2Z A;  1XFU A;  4EFS A;  1R54 A;  4ILW D;  2XS4 A;  2MZE A;  4FU4 A;  4PKV A;  4JA1 A;  1KUI A;  4H82 A;  3B8Z A;  1SLM A;  1UMT A;  2Z2D A;  3TSK A;  2OW2 A;  2WOA A;  4JP4 A;  4JIJ A;  3LJZ A;  4H3X A;  1GKC A;  5D1S A;  1JIZ A;  1Q3A A;  3GBO A;  1PWP A;  1CQR A;  1HV5 A;  1EB6 A;  1IAC A;  4DF9 A;  1KUK A;  3DTI A;  3KME A;  1ZTQ A;  4GR0 A;  1L6J A;  4GF1 A;  2SRT A;  1K7Q A;  2MLR A;  1XFZ A;  1R55 A;  2OXW A;  4XCT A;  2D1O A;  1AKL A;  1O0Q A;  1G05 A;  2Y6C A;  4PKW A;  1B8Y A;  1GE5 A;  4G9L A;  1YOU A;  4HMA A;  1YP1 A;  3OHO A;  1XFW A;  4I03 A;  4ON1 A;  1BQQ M;  1O0T A;  1SLN A;  1UEA A;  2W0D A;  3L0V A;  5D3C A;  3LGP A;  4G0D A;  3KMC A;  2KRJ A;  4AYK A;  1GE7 A;  2ERO A;  2D1N A;  1DTH A;  1JAN A;  2L0R A;  1B3D A;  5CUH A;  4GWM A;  1PWQ A;  2WO9 A;  1EAK A;  3EDH A;  2ERQ A;  3LJG A;  4CTH A;  2OXZ A;  3TS4 A;  1I73 A;  5H8X A;  1RM8 A;  3F1A A;  3KEJ A;  5D1U A;  2MZH A;  3KEK A;  1ZS0 A;  2CKI A;  3ZVS A;  1G12 A;  4PKS A;  1I1I P;  1BIW A;  2J83 A;  4IUW A;  4PKR A;  3F16 A;  1ND1 A;  3LUN A;  1Y8J A;  1JIW P;  1BM6 A;  4DPE A;  1SU3 A;  4J4M A;  5I4O A;  4FXQ A;  1HFS A;  2YIG A;  2JNP A;  1JAP A;  4Q1L A;  4HX3 A;  1XUR A;  1Y0V A;  2W12 A;  3AIG A;  3RTS A;  1D8M A;  1GO7 P;  1IAD A;  2RJQ A;  1OM6 A;  5L79 A;  1C8T A;  2OVX A;  3G5C A;  4FVL A;  3HDA P;  1PWV A;  2X7M A;  1BKC A;  1DMT A;  4PKQ A;  3HYG A;  1CAQ A;  3LK8 A;  3OHL A;  456C A;  1UMS A;  1JH1 A;  5B5P A;  3EDG A;  1G4K A;  2W13 A;  3VI1 A;  5CZM A;  1QIC A;  2DW2 A;  1AYK A;  4IJO A;  1GE6 A;  3I7G A;  4R3V A;  3N2U A;  5B5O A;  4GR3 A;  3EDZ A;  2A8H A;  3USN A;  4PKU A;  1R1H A;  1XUD A;  4XM6 A;  4AIG A;  1XFY A;  3DPF A;  1SMP A;  3LKA A;  4GWN A;  2WO8 A;  3I7I A;  4AXQ A;  3E8R A;  1WNI A;  3HDB A;  3LIR A;  1ZXV A;  1CGE A;  3ZXH A;  1D8F A;  1PWW A;  2CLT A;  4WKI A;  2OW9 A;  2J0T A;  1QIB A;  2XS3 A;  4JPA A;  5I12 A;  1IAA A;  4H76 A;  2AYK A;  1SRP A;  2X3C A;  1BSW A;  1QJI A;  1HTD A;  4PKT A; 
#chains in the Genus database with same CATH homology
 5I2Z A;  5JMY A;  3V96 B;  4H30 A;  1JAQ A;  1QJJ A;  1BUD A;  2X3B A;  1QUA A;  3DWB A;  1C7K A;  4A3W A;  2ERP A;  1OS2 A;  4H1Q A;  2POJ A;  3KEC A;  1EUB A;  4A7B A;  3O2X A;  1CXV A;  1BZS A;  3F15 A;  3LQ0 A;  1FLS A;  1MNC A;  4GR8 A;  1ROS A;  3L0T A;  3Q2H A;  4H49 A;  1GXD A;  2TCL A;  1OM8 A;  1AF0 A;  1GO8 P;  1K7G A;  1ZP5 A;  2JIH A;  1OS9 A;  2JT5 A;  2MZI A;  3LUM A;  2K2G A;  1KUG A;  4GUY A;  1HFC A;  1D7X A;  1UTZ A;  1R1J A;  1HY7 A;  2AIG P;  2DDF A;  1BKC I;  1ATL A;  1JAO A;  1OMJ A;  2OW0 A;  3TVC A;  3KHI A;  4L19 A;  1G9K A;  3LIK A;  3WV1 A;  2X3A A;  1S4B P;  3DTE A;  4XBH A;  966C A;  3O64 A;  4L7A A;  1XFX A;  3DPE A;  3ZUK A;  3AYU A;  1A85 A;  1H71 P;  2DDY A;  2E2D A;  1YQY A;  3B92 A;  3P24 A;  1CGL A;  2HU6 A;  1D5J A;  2MLS A;  4WK7 A;  2JSD A;  1PWU A;  3EHX A;  3KWV C;  1CIZ A;  3HBU P;  3LQB A;  1JKY A;  1IAG A;  4H84 A;  1BKC E;  1MMR A;  3HY7 A;  3DSL A;  2QPJ A;  4JQG A;  1FM1 A;  3U1R A;  1G49 A;  5D7W A;  2DW1 A;  1MMB A;  2USN A;  1OM7 A;  5BOY A;  3P1V A;  3G42 A;  3N2V A;  2OY4 A;  2RJP A;  3LE9 A;  1OO9 A;  3MA2 A;  1IAB A;  2Y6D A;  5BPA A;  5I3M A;  5I43 A;  1IAE A;  1Y93 A;  2K9C A;  3LIL A;  4L63 A;  5CXA A;  3WV3 A;  1JJ9 A;  2OI0 A;  3Q2G A;  5D2B A;  1J7N A;  1BUV M;  1ZXC A;  1MMQ A;  1FBL A;  1YCM A;  1CK7 A;  2N8R A;  3RTT A;  3VTG A;  2YUF A;  3LJT A;  3SHI A;  3KRY A;  4DV8 A;  1USN A;  1JK3 A;  1K7I A;  1GKD A;  1RMZ A;  4I35 A;  3HY9 A;  1KAP P;  4FXY P;  3ELM A;  3F19 A;  4AUO A;  5D1T A;  1KUF A;  5I0L A;  4XM8 A;  1C3I A;  2W14 A;  1I76 A;  4QKZ A;  4IN9 A;  3K7L A;  2OY2 A;  3HBV P;  3HB2 P;  1ZVX A;  4WZV A;  2O3E A;  1UTT A;  1XFV A;  3LEA A;  4WF6 A;  3AYK A;  2PJT A;  3NX7 A;  3DNG A;  4XM7 A;  2I47 A;  1AST A;  2OXU A;  3EWJ A;  4WKE A;  3BA0 A;  1KUH A;  3F17 A;  5L7F A;  1MMP A;  2E3X A;  2JT6 A;  5LAB A;  2O36 A;  1SAT A;  1CGF A;  2V4B A;  2W15 A;  4GQL A;  1XUC A;  4L6T A;  2YB9 A;  3K7N A;  5BOT A;  3CKI A;  1HOV A;  1BQO A;  1KBC A;  3TT4 A;  1A86 A;  3DL1 A;  2FV5 A;  3DTK A;  3EDI A;  2OZR A;  3WV2 A;  1QIA A;  3F18 A;  3UVC A;  4ZR5 A;  4H2E A;  2FV9 A;  2OW1 A;  1R1I A;  1Z3J A;  2DW0 A;  4DD8 A;  2OVZ A;  3EHY A;  3LMC A;  830C A;  3B2Z A;  1XFU A;  4EFS A;  1R54 A;  4ILW D;  2XS4 A;  2MZE A;  4FU4 A;  4PKV A;  4JA1 A;  1KUI A;  4H82 A;  3B8Z A;  1SLM A;  1UMT A;  2Z2D A;  3TSK A;  2OW2 A;  2WOA A;  4JP4 A;  4JIJ A;  3LJZ A;  4H3X A;  1GKC A;  5D1S A;  1JIZ A;  1Q3A A;  3GBO A;  1PWP A;  1CQR A;  1HV5 A;  1EB6 A;  1IAC A;  4DF9 A;  1KUK A;  3DTI A;  3KME A;  1ZTQ A;  4GR0 A;  1L6J A;  4GF1 A;  2SRT A;  1K7Q A;  2MLR A;  1XFZ A;  1R55 A;  2OXW A;  4XCT A;  2D1O A;  1AKL A;  1O0Q A;  1G05 A;  2Y6C A;  4PKW A;  1B8Y A;  1GE5 A;  4G9L A;  1YOU A;  4HMA A;  1YP1 A;  3OHO A;  1XFW A;  4I03 A;  4ON1 A;  1BQQ M;  1O0T A;  1SLN A;  1UEA A;  2W0D A;  3L0V A;  5D3C A;  3LGP A;  4G0D A;  3KMC A;  2KRJ A;  4AYK A;  1GE7 A;  2ERO A;  2D1N A;  1DTH A;  1JAN A;  2L0R A;  1B3D A;  5CUH A;  4GWM A;  1PWQ A;  2WO9 A;  1EAK A;  3EDH A;  2ERQ A;  3LJG A;  4CTH A;  2OXZ A;  3TS4 A;  1I73 A;  5H8X A;  1RM8 A;  3F1A A;  3KEJ A;  5D1U A;  2MZH A;  3KEK A;  1ZS0 A;  2CKI A;  3ZVS A;  1G12 A;  4PKS A;  1I1I P;  1BIW A;  2J83 A;  4IUW A;  4PKR A;  3F16 A;  1ND1 A;  3LUN A;  1Y8J A;  1JIW P;  1BM6 A;  4DPE A;  1SU3 A;  4J4M A;  5I4O A;  4FXQ A;  1HFS A;  2YIG A;  2JNP A;  1JAP A;  4Q1L A;  4HX3 A;  1XUR A;  1Y0V A;  2W12 A;  3AIG A;  3RTS A;  1D8M A;  1GO7 P;  1IAD A;  2RJQ A;  1OM6 A;  5L79 A;  1C8T A;  2OVX A;  3G5C A;  4FVL A;  3HDA P;  1PWV A;  2X7M A;  1BKC A;  1DMT A;  4PKQ A;  3HYG A;  1CAQ A;  3LK8 A;  3OHL A;  456C A;  1UMS A;  1JH1 A;  5B5P A;  3EDG A;  1G4K A;  2W13 A;  3VI1 A;  5CZM A;  1QIC A;  2DW2 A;  1AYK A;  4IJO A;  1GE6 A;  3I7G A;  4R3V A;  3N2U A;  5B5O A;  4GR3 A;  3EDZ A;  2A8H A;  3USN A;  4PKU A;  1R1H A;  1XUD A;  4XM6 A;  4AIG A;  1XFY A;  3DPF A;  1SMP A;  3LKA A;  4GWN A;  2WO8 A;  3I7I A;  4AXQ A;  3E8R A;  1WNI A;  3HDB A;  3LIR A;  1ZXV A;  1CGE A;  3ZXH A;  1D8F A;  1PWW A;  2CLT A;  4WKI A;  2OW9 A;  2J0T A;  1QIB A;  2XS3 A;  4JPA A;  5I12 A;  1IAA A;  4H76 A;  2AYK A;  1SRP A;  2X3C A;  1BSW A;  1QJI A;  1HTD A;  4PKT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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