2FV5A

Crystal structure of tace in complex with ik682
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
261
structure length
261
Chain Sequence
ADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSNA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords ADAM 17
publication title IK682, a tight binding inhibitor of TACE.
pubmed doi rcsb
source organism Homo sapiens
total genus 81
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2006-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2fv5A00
2K2GA 3HY9A 2USNA 3WV2A 2AYKA 4L63A 3KEKA 2OW1A 2W0DA 2MZEA 5BPAA 3P24A 2OW2A 2OZRA 3TSKA 3L0TA 1XUCA 5H8XA 2RJQA 3Q2GA 3ZVSA 2DDFA 2I47A 1KBCA 1GO8P 3E8RA 1KUFA 1SATA 3N2UA 2OVXA 3B2ZA 3U1RA 4L6TA 3LJZA 2PJTA 1MMPA 1Y0VA 1JAOA 1ZXCA 3K7NA 2OXUA 1CXVA 2XS3A 3HDAP 2ERPA 5I4OA 5D3CA 1BQOA 1I76A 1YP1A 2MLSA 5BOYA 4H30A 2POJA 1BKCI 2FV5A 1ROSA 966CA 1OO9A 1QUAA 2V4BA 4A7BA 2W14A 1UMTA 1XFWA 3KEJA 2ERQA 2SRTA 2J0TA 1ZVXA 1CQRA 1IAEA 1OM8A 3ZUKA 3LQ0A 1R1HA 2J83A 2DW2A 5JMYA 1CAQA 1XFVA 1IABA 3HYGA 3OHLA 4G9LA 2JT5A 1H71P 1A86A 2QPJA 1ZS0A 2N8RA 1Q3AA 1JAPA 3AIGA 3EHYA 4GUYA 1ZXVA 1CGLA 2MLRA 2WO8A 3TT4A 3DNGA 1ATLA 5I2ZA 3F17A 3K7LA 4AYKA 1G12A 1SRPA 3LK8A 5D1SA 1AYKA 1KUGA 2JNPA 3VI1A 1GE5A 4I03A 4H76A 1MMQA 1BSWA 2TCLA 3LUNA 1JJ9A 3KHIA 3KRYA 4IUWA 1D7XA 2YB9A 2HU6A 2X3CA 1R1JA 3CKIA 5D2BA 3LMCA 4PKTA 2KRJA 3Q2HA 1JANA 3F18A 1KUHA 1I73A 5I0LA 2O3EA 4WKIA 2K9CA 4GF1A 1XFZA 1QIAA 1USNA 1XFYA 2X3BA 1BUDA 5L7FA 1K7GA 2RJPA 4ON1A 3B8ZA 1OM6A 2X7MA 1D5JA 5I43A 1QIBA 1UTZA 3DSLA 1B8YA 1SMPA 2W15A 1XFXA 5BOTA 3MA2A 1MMBA 4HMAA 4DF9A 2Y6DA 5D7WA 3DPEA 3OHOA 1OM7A 2W13A 2E2DA 2OW9A 3I7GA 2O36A 1UTTA 1EUBA 3AYUA 3LJTA 3VTGA 4R3VA 4XM8A 1OMJA 2D1NA 1JAQA 1DMTA 1Z3JA 3G5CA 1EB6A 5CUHA 1BIWA 1MNCA 2OW0A 1HTDA 3RTTA 4JP4A 1BKCE 2Z2DA 2JT6A 4PKQA 4PKVA 4H2EA 1PWQA 4FXYP 1GXDA 3TS4A 3LJGA 3KMEA 4IJOA 4FVLA 4I35A 3AYKA 4EFSA 1G9KA 4XM6A 3ELMA 1GKCA 1HOVA 1G05A 3SHIA 2WO9A 3LEAA 3F15A 1PWVA 4ILWD 1OS9A 1B3DA 1O0TA 4PKRA 3EDGA 1IACA 2DW0A 1GKDA 1QICA 4DPEA 1UEAA 5CZMA 1AF0A 4XM7A 1AKLA 1JH1A 1O0QA 2X3AA 4HX3A 1UMSA 4PKUA 1R1IA 4JA1A 1BUVM 1FM1A 1IADA 1SU3A 4FU4A 4H82A 3L0VA 1QJJA 2JIHA 3N2VA 4AXQA 3LILA 4GWNA 2CLTA 3BA0A 2AIGP 4L19A 1YQYA 3V96B 1Y8JA 4CTHA 3EWJA 1GO7P 3DWBA 3O2XA 3KECA 4G0DA 3HB2P 1IAAA 4JPAA 4H3XA 3B92A 1FBLA 1CGFA 4WKEA 1GE7A 1I1IP 1R55A 3F16A 3RTSA 3KWVC 1ASTA 3GBOA 1G4KA 3DPFA 2OVZA 1G49A 3EDIA 1KAPP 1FLSA 2OY4A 1EAKA 3I7IA 1K7QA 3DL1A 1IAGA 1RM8A 3UVCA 4GR3A 4DD8A 1C3IA 1ND1A 3LKAA 4WZVA 2E3XA 1BZSA 3LIRA 4WK7A 3USNA 2FV9A 2MZIA 2OI0A 2W12A 2Y6CA 4H49A 1DTHA 2JSDA 3G42A 2WOAA 1QJIA 3F19A 1L6JA 3ZXHA 3LIKA 4PKSA 2MZHA 1GE6A 3LQBA 2XS4A 4JIJA 3TVCA 1PWUA 1RMZA 3LGPA 3O64A 5CXAA 5B5PA 1SLMA 1JK3A 1BQQM 2DW1A 4H84A 1J7NA 1CGEA 1S4BP 2OY2A 4PKWA 4H1QA 1OS2A 3NX7A 2OXWA 830CA 5I3MA 1XFUA 4GR8A 4IN9A 4AIGA 1D8MA 3P1VA 4GQLA 5D1UA 4A3WA 4ZR5A 1CK7A 3LUMA 1HY7A 3HDBA 5D1TA 4XCTA 1KUKA 3EHXA 4XBHA 4GWMA 1Y93A 1HV5A 4GR0A 1BM6A 4Q1LA 3KMCA 1WNIA 2YIGA 2L0RA 4DV8A 2DDYA 3LE9A 1SLNA 1PWWA 1K7IA 1XURA 1C7KA 1ZTQA 3EDHA 1C8TA 1YOUA 3HY7A 5I12A 1D8FA 3HBVP 3EDZA 1BKCA 5L79A 1JKYA 1KUIA 1MMRA 5LABA 1PWPA 1JIWP 1R54A 2EROA 1HFSA 5B5OA 456CA 3F1AA 4QKZA 3WV3A 1ZP5A 4J4MA 1YCMA 2D1OA 1CIZA 1JIZA 2OXZA 2CKIA 3WV1A 1XUDA 4AUOA 4JQGA 1A85A 4WF6A 1HFCA 3HBUP 4FXQA 2A8HA
chains in the Genus database with same CATH superfamily
2K2GA 3HY9A 2USNA 3WV2A 2AYKA 4L63A 3KEKA 2OW1A 2W0DA 2MZEA 5BPAA 3P24A 2OW2A 2OZRA 3TSKA 3L0TA 1XUCA 5H8XA 2RJQA 3Q2GA 3ZVSA 2DDFA 2I47A 1KBCA 1GO8P 3E8RA 1KUFA 1SATA 3N2UA 2OVXA 3B2ZA 3U1RA 4L6TA 3LJZA 2PJTA 1MMPA 1Y0VA 1JAOA 1ZXCA 3K7NA 2OXUA 1CXVA 2XS3A 3HDAP 2ERPA 5I4OA 5D3CA 1BQOA 1I76A 1YP1A 2MLSA 5BOYA 4H30A 2POJA 1BKCI 2FV5A 1ROSA 966CA 1OO9A 1QUAA 2V4BA 4A7BA 2W14A 1UMTA 1XFWA 3KEJA 2ERQA 2SRTA 2J0TA 1ZVXA 1CQRA 1IAEA 1OM8A 3ZUKA 3LQ0A 1R1HA 2J83A 2DW2A 5JMYA 1CAQA 1XFVA 1IABA 3HYGA 3OHLA 4G9LA 2JT5A 1H71P 1A86A 2QPJA 1ZS0A 2N8RA 1Q3AA 1JAPA 3AIGA 3EHYA 4GUYA 1ZXVA 1CGLA 2MLRA 2WO8A 3TT4A 3DNGA 1ATLA 5I2ZA 3F17A 3K7LA 4AYKA 1G12A 1SRPA 3LK8A 5D1SA 1AYKA 1KUGA 2JNPA 3VI1A 1GE5A 4I03A 3DTIA 4H76A 1MMQA 1BSWA 2TCLA 3LUNA 1JJ9A 3KHIA 3KRYA 4IUWA 1D7XA 2YB9A 2HU6A 2X3CA 1R1JA 3CKIA 5D2BA 3LMCA 4PKTA 2KRJA 3Q2HA 1JANA 3F18A 1KUHA 1I73A 5I0LA 1TVIA 2O3EA 4WKIA 2K9CA 4GF1A 1XFZA 1QIAA 1USNA 1XFYA 2X3BA 1BUDA 5L7FA 1K7GA 2RJPA 4ON1A 3B8ZA 1OM6A 2X7MA 1D5JA 5I43A 1QIBA 1UTZA 3DSLA 1B8YA 1SMPA 2W15A 1XFXA 5BOTA 3MA2A 1MMBA 4HMAA 4DF9A 2Y6DA 5D7WA 3DPEA 3OHOA 1OM7A 2W13A 2E2DA 2OW9A 3I7GA 2O36A 1UTTA 1EUBA 3AYUA 3LJTA 3VTGA 4R3VA 4XM8A 1OMJA 2D1NA 1JAQA 1DMTA 1Z3JA 3G5CA 1EB6A 5CUHA 1BIWA 1MNCA 2OW0A 1HTDA 3RTTA 4JP4A 1BKCE 2Z2DA 2JT6A 4PKQA 4PKVA 4H2EA 1PWQA 4FXYP 1GXDA 3TS4A 3LJGA 3KMEA 4IJOA 4FVLA 4I35A 3AYKA 4EFSA 1G9KA 4XM6A 3ELMA 1GKCA 1HOVA 1G05A 4L7AA 3SHIA 2WO9A 3LEAA 3F15A 1PWVA 4ILWD 1OS9A 1B3DA 1O0TA 4PKRA 3EDGA 1IACA 2DW0A 1GKDA 1QICA 4DPEA 1UEAA 5CZMA 1AF0A 4XM7A 1AKLA 1JH1A 1O0QA 2X3AA 4HX3A 1UMSA 4PKUA 1R1IA 4JA1A 1BUVM 1FM1A 1IADA 1SU3A 4FU4A 4H82A 3L0VA 1QJJA 2JIHA 3N2VA 4AXQA 3LILA 4GWNA 2CLTA 3BA0A 2AIGP 4L19A 1YQYA 3DTKA 3V96B 1Y8JA 4CTHA 3EWJA 1GO7P 3DWBA 3O2XA 3KECA 4G0DA 3HB2P 1IAAA 4JPAA 4H3XA 3B92A 1FBLA 1CGFA 4WKEA 1GE7A 1I1IP 1R55A 3F16A 3RTSA 3KWVC 1ASTA 3GBOA 1G4KA 3DPFA 2OVZA 2YUFA 1G49A 3EDIA 1KAPP 1FLSA 2OY4A 1EAKA 3I7IA 1K7QA 3DL1A 1IAGA 1RM8A 3UVCA 4GR3A 4DD8A 1C3IA 1ND1A 3LKAA 4WZVA 2E3XA 1BZSA 3LIRA 4WK7A 3USNA 2FV9A 2MZIA 2OI0A 2W12A 2Y6CA 4H49A 1DTHA 1XAXA 2JSDA 3G42A 2WOAA 1QJIA 3F19A 1L6JA 3ZXHA 3LIKA 4PKSA 2MZHA 1GE6A 3LQBA 2XS4A 4JIJA 3TVCA 1PWUA 1RMZA 3LGPA 3O64A 5CXAA 5B5PA 1SLMA 1JK3A 1BQQM 2DW1A 4H84A 1J7NA 1CGEA 1S4BP 2OY2A 3DTEA 4PKWA 4H1QA 1OS2A 3NX7A 2OXWA 830CA 5I3MA 1XFUA 4GR8A 4IN9A 4AIGA 1D8MA 3P1VA 4GQLA 5D1UA 4A3WA 4ZR5A 1CK7A 3LUMA 1HY7A 3HDBA 5D1TA 4XCTA 1KUKA 3EHXA 4XBHA 4GWMA 1Y93A 1HV5A 4GR0A 1BM6A 4Q1LA 1OZ9A 3KMCA 1WNIA 2YIGA 2L0RA 4DV8A 2DDYA 3LE9A 1SLNA 1PWWA 1K7IA 1XURA 1C7KA 1ZTQA 3EDHA 1C8TA 1YOUA 3HY7A 5I12A 1D8FA 3HBVP 3EDZA 1BKCA 5L79A 1JKYA 1KUIA 1MMRA 5LABA 1PWPA 1JIWP 1R54A 2EROA 1HFSA 5B5OA 1XM5A 456CA 3F1AA 4QKZA 3WV3A 1ZP5A 4J4MA 1YCMA 2D1OA 1CIZA 1JIZA 2OXZA 2CKIA 3WV1A 1XUDA 4AUOA 4JQGA 1A85A 4WF6A 1HFCA 3HBUP 4FXQA 2A8HA
chains in the Genus database with same CATH topology
2K2GA 3HY9A 2USNA 3WV2A 2AYKA 4L63A 3KEKA 2OW1A 2W0DA 2MZEA 5BPAA 3P24A 2OW2A 2OZRA 3TSKA 3L0TA 1XUCA 5H8XA 2RJQA 3Q2GA 3ZVSA 2DDFA 2I47A 1KBCA 1GO8P 3E8RA 1KUFA 1SATA 3N2UA 2OVXA 3B2ZA 3U1RA 4L6TA 3LJZA 2PJTA 1MMPA 1Y0VA 1JAOA 1ZXCA 3K7NA 2OXUA 1CXVA 2XS3A 3HDAP 2ERPA 5I4OA 5D3CA 1BQOA 1I76A 1YP1A 2MLSA 5BOYA 4H30A 2POJA 1BKCI 2FV5A 1ROSA 966CA 1OO9A 1QUAA 2V4BA 4A7BA 2W14A 1UMTA 1XFWA 3KEJA 2ERQA 2SRTA 2J0TA 1ZVXA 1CQRA 1IAEA 1OM8A 3ZUKA 3LQ0A 1R1HA 2J83A 2DW2A 5JMYA 1CAQA 1XFVA 1IABA 3HYGA 3OHLA 4G9LA 2JT5A 1H71P 1A86A 2QPJA 1ZS0A 2N8RA 1Q3AA 1JAPA 3AIGA 3EHYA 4GUYA 1ZXVA 1CGLA 2MLRA 2WO8A 3TT4A 3DNGA 1ATLA 5I2ZA 3F17A 3K7LA 4AYKA 1G12A 1SRPA 3LK8A 5D1SA 1AYKA 1KUGA 2JNPA 3VI1A 1GE5A 4I03A 3DTIA 4H76A 1MMQA 1BSWA 2TCLA 3LUNA 1JJ9A 3KHIA 3KRYA 4IUWA 1D7XA 2YB9A 2HU6A 2X3CA 1R1JA 3CKIA 5D2BA 3LMCA 4PKTA 2KRJA 3Q2HA 1JANA 3F18A 1KUHA 1I73A 5I0LA 2O3EA 4WKIA 2K9CA 4GF1A 1XFZA 1QIAA 1USNA 1XFYA 2X3BA 1BUDA 5L7FA 1K7GA 2RJPA 4ON1A 3B8ZA 1OM6A 2X7MA 1D5JA 5I43A 1QIBA 1UTZA 3DSLA 1B8YA 1SMPA 2W15A 1XFXA 5BOTA 3MA2A 1MMBA 4HMAA 4DF9A 2Y6DA 5D7WA 3DPEA 3OHOA 1OM7A 2W13A 2E2DA 2OW9A 3I7GA 2O36A 1UTTA 1EUBA 3AYUA 3LJTA 3VTGA 4R3VA 4XM8A 1OMJA 2D1NA 1JAQA 1DMTA 1Z3JA 3G5CA 1EB6A 5CUHA 1BIWA 1MNCA 2OW0A 1HTDA 3RTTA 4JP4A 1BKCE 2Z2DA 2JT6A 4PKQA 4PKVA 4H2EA 1PWQA 4FXYP 1GXDA 3TS4A 3LJGA 3KMEA 4IJOA 4FVLA 4I35A 3AYKA 4EFSA 1G9KA 4XM6A 3ELMA 1GKCA 1HOVA 1G05A 4L7AA 3SHIA 2WO9A 3LEAA 3F15A 1PWVA 4ILWD 1OS9A 1B3DA 1O0TA 4PKRA 3EDGA 1IACA 2DW0A 1GKDA 1QICA 4DPEA 1UEAA 5CZMA 1AF0A 4XM7A 1AKLA 1JH1A 1O0QA 2X3AA 4HX3A 1UMSA 4PKUA 1R1IA 4JA1A 1BUVM 1FM1A 1IADA 1SU3A 4FU4A 4H82A 3L0VA 1QJJA 2JIHA 3N2VA 4AXQA 3LILA 4GWNA 2CLTA 3BA0A 2AIGP 4L19A 1YQYA 3DTKA 3V96B 1Y8JA 4CTHA 3EWJA 1GO7P 3DWBA 3O2XA 3KECA 4G0DA 3HB2P 1IAAA 4JPAA 4H3XA 3B92A 1FBLA 1CGFA 4WKEA 1GE7A 1I1IP 1R55A 3F16A 3RTSA 3KWVC 1ASTA 3GBOA 1G4KA 3DPFA 2OVZA 2YUFA 1G49A 3EDIA 1KAPP 1FLSA 2OY4A 1EAKA 3I7IA 1K7QA 3DL1A 1IAGA 1RM8A 3UVCA 4GR3A 4DD8A 1C3IA 1ND1A 3LKAA 4WZVA 2E3XA 1BZSA 3LIRA 4WK7A 3USNA 2FV9A 2MZIA 2OI0A 2W12A 2Y6CA 4H49A 1DTHA 2JSDA 3G42A 2WOAA 1QJIA 3F19A 1L6JA 3ZXHA 3LIKA 4PKSA 2MZHA 1GE6A 3LQBA 2XS4A 4JIJA 3TVCA 1PWUA 1RMZA 3LGPA 3O64A 5CXAA 5B5PA 1SLMA 1JK3A 1BQQM 2DW1A 4H84A 1J7NA 1CGEA 1S4BP 2OY2A 3DTEA 4PKWA 4H1QA 1OS2A 3NX7A 2OXWA 830CA 5I3MA 1XFUA 4GR8A 4IN9A 4AIGA 1D8MA 3P1VA 4GQLA 5D1UA 4A3WA 4ZR5A 1CK7A 3LUMA 1HY7A 3HDBA 5D1TA 4XCTA 1KUKA 3EHXA 4XBHA 4GWMA 1Y93A 1HV5A 4GR0A 1BM6A 4Q1LA 3KMCA 1WNIA 2YIGA 2L0RA 4DV8A 2DDYA 3LE9A 1SLNA 1PWWA 1K7IA 1XURA 1C7KA 1ZTQA 3EDHA 1C8TA 1YOUA 3HY7A 5I12A 1D8FA 3HBVP 3EDZA 1BKCA 5L79A 1JKYA 1KUIA 1MMRA 5LABA 1PWPA 1JIWP 1R54A 2EROA 1HFSA 5B5OA 456CA 3F1AA 4QKZA 3WV3A 1ZP5A 4J4MA 1YCMA 2D1OA 1CIZA 1JIZA 2OXZA 2CKIA 3WV1A 1XUDA 4AUOA 4JQGA 1A85A 4WF6A 1HFCA 3HBUP 4FXQA 2A8HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K2G A;  3HY9 A;  2USN A;  3WV2 A;  2AYK A;  4L63 A;  3KEK A;  2OW1 A;  2W0D A;  2MZE A;  5BPA A;  3P24 A;  2OW2 A;  2OZR A;  3TSK A;  3L0T A;  1XUC A;  5H8X A;  2RJQ A;  3Q2G A;  3ZVS A;  2DDF A;  2I47 A;  1KBC A;  1GO8 P;  3E8R A;  1KUF A;  1SAT A;  3N2U A;  2OVX A;  3B2Z A;  3U1R A;  4L6T A;  3LJZ A;  2PJT A;  1MMP A;  1Y0V A;  1JAO A;  1ZXC A;  3K7N A;  2OXU A;  1CXV A;  2XS3 A;  3HDA P;  2ERP A;  5I4O A;  5D3C A;  1BQO A;  1I76 A;  1YP1 A;  2MLS A;  5BOY A;  4H30 A;  2POJ A;  1BKC I;  2FV5 A;  1ROS A;  966C A;  1OO9 A;  1QUA A;  2V4B A;  4A7B A;  2W14 A;  1UMT A;  1XFW A;  3KEJ A;  2ERQ A;  2SRT A;  2J0T A;  1ZVX A;  1CQR A;  1IAE A;  1OM8 A;  3ZUK A;  3LQ0 A;  1R1H A;  2J83 A;  2DW2 A;  5JMY A;  1CAQ A;  1XFV A;  1IAB A;  3HYG A;  3OHL A;  4G9L A;  2JT5 A;  1H71 P;  1A86 A;  2QPJ A;  1ZS0 A;  2N8R A;  1Q3A A;  1JAP A;  3AIG A;  3EHY A;  4GUY A;  1ZXV A;  1CGL A;  2MLR A;  2WO8 A;  3TT4 A;  3DNG A;  1ATL A;  5I2Z A;  3F17 A;  3K7L A;  4AYK A;  1G12 A;  1SRP A;  3LK8 A;  5D1S A;  1AYK A;  1KUG A;  2JNP A;  3VI1 A;  1GE5 A;  4I03 A;  4H76 A;  1MMQ A;  1BSW A;  2TCL A;  3LUN A;  1JJ9 A;  3KHI A;  3KRY A;  4IUW A;  1D7X A;  2YB9 A;  2HU6 A;  2X3C A;  1R1J A;  3CKI A;  5D2B A;  3LMC A;  4PKT A;  2KRJ A;  3Q2H A;  1JAN A;  3F18 A;  1KUH A;  1I73 A;  5I0L A;  2O3E A;  4WKI A;  2K9C A;  4GF1 A;  1XFZ A;  1QIA A;  1USN A;  1XFY A;  2X3B A;  1BUD A;  5L7F A;  1K7G A;  2RJP A;  4ON1 A;  3B8Z A;  1OM6 A;  2X7M A;  1D5J A;  5I43 A;  1QIB A;  1UTZ A;  3DSL A;  1B8Y A;  1SMP A;  2W15 A;  1XFX A;  5BOT A;  3MA2 A;  1MMB A;  4HMA A;  4DF9 A;  2Y6D A;  5D7W A;  3DPE A;  3OHO A;  1OM7 A;  2W13 A;  2E2D A;  2OW9 A;  3I7G A;  2O36 A;  1UTT A;  1EUB A;  3AYU A;  3LJT A;  3VTG A;  4R3V A;  4XM8 A;  1OMJ A;  2D1N A;  1JAQ A;  1DMT A;  1Z3J A;  3G5C A;  1EB6 A;  5CUH A;  1BIW A;  1MNC A;  2OW0 A;  1HTD A;  3RTT A;  4JP4 A;  1BKC E;  2Z2D A;  2JT6 A;  4PKQ A;  4PKV A;  4H2E A;  1PWQ A;  4FXY P;  1GXD A;  3TS4 A;  3LJG A;  3KME A;  4IJO A;  4FVL A;  4I35 A;  3AYK A;  4EFS A;  1G9K A;  4XM6 A;  3ELM A;  1GKC A;  1HOV A;  1G05 A;  3SHI A;  2WO9 A;  3LEA A;  3F15 A;  1PWV A;  4ILW D;  1OS9 A;  1B3D A;  1O0T A;  4PKR A;  3EDG A;  1IAC A;  2DW0 A;  1GKD A;  1QIC A;  4DPE A;  1UEA A;  5CZM A;  1AF0 A;  4XM7 A;  1AKL A;  1JH1 A;  1O0Q A;  2X3A A;  4HX3 A;  1UMS A;  4PKU A;  1R1I A;  4JA1 A;  1BUV M;  1FM1 A;  1IAD A;  1SU3 A;  4FU4 A;  4H82 A;  3L0V A;  1QJJ A;  2JIH A;  3N2V A;  4AXQ A;  3LIL A;  4GWN A;  2CLT A;  3BA0 A;  2AIG P;  4L19 A;  1YQY A;  3V96 B;  1Y8J A;  4CTH A;  3EWJ A;  1GO7 P;  3DWB A;  3O2X A;  3KEC A;  4G0D A;  3HB2 P;  1IAA A;  4JPA A;  4H3X A;  3B92 A;  1FBL A;  1CGF A;  4WKE A;  1GE7 A;  1I1I P;  1R55 A;  3F16 A;  3RTS A;  3KWV C;  1AST A;  3GBO A;  1G4K A;  3DPF A;  2OVZ A;  1G49 A;  3EDI A;  1KAP P;  1FLS A;  2OY4 A;  1EAK A;  3I7I A;  1K7Q A;  3DL1 A;  1IAG A;  1RM8 A;  3UVC A;  4GR3 A;  4DD8 A;  1C3I A;  1ND1 A;  3LKA A;  4WZV A;  2E3X A;  1BZS A;  3LIR A;  4WK7 A;  3USN A;  2FV9 A;  2MZI A;  2OI0 A;  2W12 A;  2Y6C A;  4H49 A;  1DTH A;  2JSD A;  3G42 A;  2WOA A;  1QJI A;  3F19 A;  1L6J A;  3ZXH A;  3LIK A;  4PKS A;  2MZH A;  1GE6 A;  3LQB A;  2XS4 A;  4JIJ A;  3TVC A;  1PWU A;  1RMZ A;  3LGP A;  3O64 A;  5CXA A;  5B5P A;  1SLM A;  1JK3 A;  1BQQ M;  2DW1 A;  4H84 A;  1J7N A;  1CGE A;  1S4B P;  2OY2 A;  4PKW A;  4H1Q A;  1OS2 A;  3NX7 A;  2OXW A;  830C A;  5I3M A;  1XFU A;  4GR8 A;  4IN9 A;  4AIG A;  1D8M A;  3P1V A;  4GQL A;  5D1U A;  4A3W A;  4ZR5 A;  1CK7 A;  3LUM A;  1HY7 A;  3HDB A;  5D1T A;  4XCT A;  1KUK A;  3EHX A;  4XBH A;  4GWM A;  1Y93 A;  1HV5 A;  4GR0 A;  1BM6 A;  4Q1L A;  3KMC A;  1WNI A;  2YIG A;  2L0R A;  4DV8 A;  2DDY A;  3LE9 A;  1SLN A;  1PWW A;  1K7I A;  1XUR A;  1C7K A;  1ZTQ A;  3EDH A;  1C8T A;  1YOU A;  3HY7 A;  5I12 A;  1D8F A;  3HBV P;  3EDZ A;  1BKC A;  5L79 A;  1JKY A;  1KUI A;  1MMR A;  5LAB A;  1PWP A;  1JIW P;  1R54 A;  2ERO A;  1HFS A;  5B5O A;  456C A;  3F1A A;  4QKZ A;  3WV3 A;  1ZP5 A;  4J4M A;  1YCM A;  2D1O A;  1CIZ A;  1JIZ A;  2OXZ A;  2CKI A;  3WV1 A;  1XUD A;  4AUO A;  4JQG A;  1A85 A;  4WF6 A;  1HFC A;  3HBU P;  4FXQ A;  2A8H A; 
#chains in the Genus database with same CATH topology
 2K2G A;  3HY9 A;  2USN A;  3WV2 A;  2AYK A;  4L63 A;  3KEK A;  2OW1 A;  2W0D A;  2MZE A;  5BPA A;  3P24 A;  2OW2 A;  2OZR A;  3TSK A;  3L0T A;  1XUC A;  5H8X A;  2RJQ A;  3Q2G A;  3ZVS A;  2DDF A;  2I47 A;  1KBC A;  1GO8 P;  3E8R A;  1KUF A;  1SAT A;  3N2U A;  2OVX A;  3B2Z A;  3U1R A;  4L6T A;  3LJZ A;  2PJT A;  1MMP A;  1Y0V A;  1JAO A;  1ZXC A;  3K7N A;  2OXU A;  1CXV A;  2XS3 A;  3HDA P;  2ERP A;  5I4O A;  5D3C A;  1BQO A;  1I76 A;  1YP1 A;  2MLS A;  5BOY A;  4H30 A;  2POJ A;  1BKC I;  2FV5 A;  1ROS A;  966C A;  1OO9 A;  1QUA A;  2V4B A;  4A7B A;  2W14 A;  1UMT A;  1XFW A;  3KEJ A;  2ERQ A;  2SRT A;  2J0T A;  1ZVX A;  1CQR A;  1IAE A;  1OM8 A;  3ZUK A;  3LQ0 A;  1R1H A;  2J83 A;  2DW2 A;  5JMY A;  1CAQ A;  1XFV A;  1IAB A;  3HYG A;  3OHL A;  4G9L A;  2JT5 A;  1H71 P;  1A86 A;  2QPJ A;  1ZS0 A;  2N8R A;  1Q3A A;  1JAP A;  3AIG A;  3EHY A;  4GUY A;  1ZXV A;  1CGL A;  2MLR A;  2WO8 A;  3TT4 A;  3DNG A;  1ATL A;  5I2Z A;  3F17 A;  3K7L A;  4AYK A;  1G12 A;  1SRP A;  3LK8 A;  5D1S A;  1AYK A;  1KUG A;  2JNP A;  3VI1 A;  1GE5 A;  4I03 A;  3DTI A;  4H76 A;  1MMQ A;  1BSW A;  2TCL A;  3LUN A;  1JJ9 A;  3KHI A;  3KRY A;  4IUW A;  1D7X A;  2YB9 A;  2HU6 A;  2X3C A;  1R1J A;  3CKI A;  5D2B A;  3LMC A;  4PKT A;  2KRJ A;  3Q2H A;  1JAN A;  3F18 A;  1KUH A;  1I73 A;  5I0L A;  1TVI A;  2O3E A;  4WKI A;  2K9C A;  4GF1 A;  1XFZ A;  1QIA A;  1USN A;  1XFY A;  2X3B A;  1BUD A;  5L7F A;  1K7G A;  2RJP A;  4ON1 A;  3B8Z A;  1OM6 A;  2X7M A;  1D5J A;  5I43 A;  1QIB A;  1UTZ A;  3DSL A;  1B8Y A;  1SMP A;  2W15 A;  1XFX A;  5BOT A;  3MA2 A;  1MMB A;  4HMA A;  4DF9 A;  2Y6D A;  5D7W A;  3DPE A;  3OHO A;  1OM7 A;  2W13 A;  2E2D A;  2OW9 A;  3I7G A;  2O36 A;  1UTT A;  1EUB A;  3AYU A;  3LJT A;  3VTG A;  4R3V A;  4XM8 A;  1OMJ A;  2D1N A;  1JAQ A;  1DMT A;  1Z3J A;  3G5C A;  1EB6 A;  5CUH A;  1BIW A;  1MNC A;  2OW0 A;  1HTD A;  3RTT A;  4JP4 A;  1BKC E;  2Z2D A;  2JT6 A;  4PKQ A;  4PKV A;  4H2E A;  1PWQ A;  4FXY P;  1GXD A;  3TS4 A;  3LJG A;  3KME A;  4IJO A;  4FVL A;  4I35 A;  3AYK A;  4EFS A;  1G9K A;  4XM6 A;  3ELM A;  1GKC A;  1HOV A;  1G05 A;  4L7A A;  3SHI A;  2WO9 A;  3LEA A;  3F15 A;  1PWV A;  4ILW D;  1OS9 A;  1B3D A;  1O0T A;  4PKR A;  3EDG A;  1IAC A;  2DW0 A;  1GKD A;  1QIC A;  4DPE A;  1UEA A;  5CZM A;  1AF0 A;  4XM7 A;  1AKL A;  1JH1 A;  1O0Q A;  2X3A A;  4HX3 A;  1UMS A;  4PKU A;  1R1I A;  4JA1 A;  1BUV M;  1FM1 A;  1IAD A;  1SU3 A;  4FU4 A;  4H82 A;  3L0V A;  1QJJ A;  2JIH A;  3N2V A;  4AXQ A;  3LIL A;  4GWN A;  2CLT A;  3BA0 A;  2AIG P;  4L19 A;  1YQY A;  3DTK A;  3V96 B;  1Y8J A;  4CTH A;  3EWJ A;  1GO7 P;  3DWB A;  3O2X A;  3KEC A;  4G0D A;  3HB2 P;  1IAA A;  4JPA A;  4H3X A;  3B92 A;  1FBL A;  1CGF A;  4WKE A;  1GE7 A;  1I1I P;  1R55 A;  3F16 A;  3RTS A;  3KWV C;  1AST A;  3GBO A;  1G4K A;  3DPF A;  2OVZ A;  2YUF A;  1G49 A;  3EDI A;  1KAP P;  1FLS A;  2OY4 A;  1EAK A;  3I7I A;  1K7Q A;  3DL1 A;  1IAG A;  1RM8 A;  3UVC A;  4GR3 A;  4DD8 A;  1C3I A;  1ND1 A;  3LKA A;  4WZV A;  2E3X A;  1BZS A;  3LIR A;  4WK7 A;  3USN A;  2FV9 A;  2MZI A;  2OI0 A;  2W12 A;  2Y6C A;  4H49 A;  1DTH A;  1XAX A;  2JSD A;  3G42 A;  2WOA A;  1QJI A;  3F19 A;  1L6J A;  3ZXH A;  3LIK A;  4PKS A;  2MZH A;  1GE6 A;  3LQB A;  2XS4 A;  4JIJ A;  3TVC A;  1PWU A;  1RMZ A;  3LGP A;  3O64 A;  5CXA A;  5B5P A;  1SLM A;  1JK3 A;  1BQQ M;  2DW1 A;  4H84 A;  1J7N A;  1CGE A;  1S4B P;  2OY2 A;  3DTE A;  4PKW A;  4H1Q A;  1OS2 A;  3NX7 A;  2OXW A;  830C A;  5I3M A;  1XFU A;  4GR8 A;  4IN9 A;  4AIG A;  1D8M A;  3P1V A;  4GQL A;  5D1U A;  4A3W A;  4ZR5 A;  1CK7 A;  3LUM A;  1HY7 A;  3HDB A;  5D1T A;  4XCT A;  1KUK A;  3EHX A;  4XBH A;  4GWM A;  1Y93 A;  1HV5 A;  4GR0 A;  1BM6 A;  4Q1L A;  1OZ9 A;  3KMC A;  1WNI A;  2YIG A;  2L0R A;  4DV8 A;  2DDY A;  3LE9 A;  1SLN A;  1PWW A;  1K7I A;  1XUR A;  1C7K A;  1ZTQ A;  3EDH A;  1C8T A;  1YOU A;  3HY7 A;  5I12 A;  1D8F A;  3HBV P;  3EDZ A;  1BKC A;  5L79 A;  1JKY A;  1KUI A;  1MMR A;  5LAB A;  1PWP A;  1JIW P;  1R54 A;  2ERO A;  1HFS A;  5B5O A;  1XM5 A;  456C A;  3F1A A;  4QKZ A;  3WV3 A;  1ZP5 A;  4J4M A;  1YCM A;  2D1O A;  1CIZ A;  1JIZ A;  2OXZ A;  2CKI A;  3WV1 A;  1XUD A;  4AUO A;  4JQG A;  1A85 A;  4WF6 A;  1HFC A;  3HBU P;  4FXQ A;  2A8H A; 
#chains in the Genus database with same CATH homology
 2K2G A;  3HY9 A;  2USN A;  3WV2 A;  2AYK A;  4L63 A;  3KEK A;  2OW1 A;  2W0D A;  2MZE A;  5BPA A;  3P24 A;  2OW2 A;  2OZR A;  3TSK A;  3L0T A;  1XUC A;  5H8X A;  2RJQ A;  3Q2G A;  3ZVS A;  2DDF A;  2I47 A;  1KBC A;  1GO8 P;  3E8R A;  1KUF A;  1SAT A;  3N2U A;  2OVX A;  3B2Z A;  3U1R A;  4L6T A;  3LJZ A;  2PJT A;  1MMP A;  1Y0V A;  1JAO A;  1ZXC A;  3K7N A;  2OXU A;  1CXV A;  2XS3 A;  3HDA P;  2ERP A;  5I4O A;  5D3C A;  1BQO A;  1I76 A;  1YP1 A;  2MLS A;  5BOY A;  4H30 A;  2POJ A;  1BKC I;  2FV5 A;  1ROS A;  966C A;  1OO9 A;  1QUA A;  2V4B A;  4A7B A;  2W14 A;  1UMT A;  1XFW A;  3KEJ A;  2ERQ A;  2SRT A;  2J0T A;  1ZVX A;  1CQR A;  1IAE A;  1OM8 A;  3ZUK A;  3LQ0 A;  1R1H A;  2J83 A;  2DW2 A;  5JMY A;  1CAQ A;  1XFV A;  1IAB A;  3HYG A;  3OHL A;  4G9L A;  2JT5 A;  1H71 P;  1A86 A;  2QPJ A;  1ZS0 A;  2N8R A;  1Q3A A;  1JAP A;  3AIG A;  3EHY A;  4GUY A;  1ZXV A;  1CGL A;  2MLR A;  2WO8 A;  3TT4 A;  3DNG A;  1ATL A;  5I2Z A;  3F17 A;  3K7L A;  4AYK A;  1G12 A;  1SRP A;  3LK8 A;  5D1S A;  1AYK A;  1KUG A;  2JNP A;  3VI1 A;  1GE5 A;  4I03 A;  3DTI A;  4H76 A;  1MMQ A;  1BSW A;  2TCL A;  3LUN A;  1JJ9 A;  3KHI A;  3KRY A;  4IUW A;  1D7X A;  2YB9 A;  2HU6 A;  2X3C A;  1R1J A;  3CKI A;  5D2B A;  3LMC A;  4PKT A;  2KRJ A;  3Q2H A;  1JAN A;  3F18 A;  1KUH A;  1I73 A;  5I0L A;  2O3E A;  4WKI A;  2K9C A;  4GF1 A;  1XFZ A;  1QIA A;  1USN A;  1XFY A;  2X3B A;  1BUD A;  5L7F A;  1K7G A;  2RJP A;  4ON1 A;  3B8Z A;  1OM6 A;  2X7M A;  1D5J A;  5I43 A;  1QIB A;  1UTZ A;  3DSL A;  1B8Y A;  1SMP A;  2W15 A;  1XFX A;  5BOT A;  3MA2 A;  1MMB A;  4HMA A;  4DF9 A;  2Y6D A;  5D7W A;  3DPE A;  3OHO A;  1OM7 A;  2W13 A;  2E2D A;  2OW9 A;  3I7G A;  2O36 A;  1UTT A;  1EUB A;  3AYU A;  3LJT A;  3VTG A;  4R3V A;  4XM8 A;  1OMJ A;  2D1N A;  1JAQ A;  1DMT A;  1Z3J A;  3G5C A;  1EB6 A;  5CUH A;  1BIW A;  1MNC A;  2OW0 A;  1HTD A;  3RTT A;  4JP4 A;  1BKC E;  2Z2D A;  2JT6 A;  4PKQ A;  4PKV A;  4H2E A;  1PWQ A;  4FXY P;  1GXD A;  3TS4 A;  3LJG A;  3KME A;  4IJO A;  4FVL A;  4I35 A;  3AYK A;  4EFS A;  1G9K A;  4XM6 A;  3ELM A;  1GKC A;  1HOV A;  1G05 A;  4L7A A;  3SHI A;  2WO9 A;  3LEA A;  3F15 A;  1PWV A;  4ILW D;  1OS9 A;  1B3D A;  1O0T A;  4PKR A;  3EDG A;  1IAC A;  2DW0 A;  1GKD A;  1QIC A;  4DPE A;  1UEA A;  5CZM A;  1AF0 A;  4XM7 A;  1AKL A;  1JH1 A;  1O0Q A;  2X3A A;  4HX3 A;  1UMS A;  4PKU A;  1R1I A;  4JA1 A;  1BUV M;  1FM1 A;  1IAD A;  1SU3 A;  4FU4 A;  4H82 A;  3L0V A;  1QJJ A;  2JIH A;  3N2V A;  4AXQ A;  3LIL A;  4GWN A;  2CLT A;  3BA0 A;  2AIG P;  4L19 A;  1YQY A;  3DTK A;  3V96 B;  1Y8J A;  4CTH A;  3EWJ A;  1GO7 P;  3DWB A;  3O2X A;  3KEC A;  4G0D A;  3HB2 P;  1IAA A;  4JPA A;  4H3X A;  3B92 A;  1FBL A;  1CGF A;  4WKE A;  1GE7 A;  1I1I P;  1R55 A;  3F16 A;  3RTS A;  3KWV C;  1AST A;  3GBO A;  1G4K A;  3DPF A;  2OVZ A;  2YUF A;  1G49 A;  3EDI A;  1KAP P;  1FLS A;  2OY4 A;  1EAK A;  3I7I A;  1K7Q A;  3DL1 A;  1IAG A;  1RM8 A;  3UVC A;  4GR3 A;  4DD8 A;  1C3I A;  1ND1 A;  3LKA A;  4WZV A;  2E3X A;  1BZS A;  3LIR A;  4WK7 A;  3USN A;  2FV9 A;  2MZI A;  2OI0 A;  2W12 A;  2Y6C A;  4H49 A;  1DTH A;  2JSD A;  3G42 A;  2WOA A;  1QJI A;  3F19 A;  1L6J A;  3ZXH A;  3LIK A;  4PKS A;  2MZH A;  1GE6 A;  3LQB A;  2XS4 A;  4JIJ A;  3TVC A;  1PWU A;  1RMZ A;  3LGP A;  3O64 A;  5CXA A;  5B5P A;  1SLM A;  1JK3 A;  1BQQ M;  2DW1 A;  4H84 A;  1J7N A;  1CGE A;  1S4B P;  2OY2 A;  3DTE A;  4PKW A;  4H1Q A;  1OS2 A;  3NX7 A;  2OXW A;  830C A;  5I3M A;  1XFU A;  4GR8 A;  4IN9 A;  4AIG A;  1D8M A;  3P1V A;  4GQL A;  5D1U A;  4A3W A;  4ZR5 A;  1CK7 A;  3LUM A;  1HY7 A;  3HDB A;  5D1T A;  4XCT A;  1KUK A;  3EHX A;  4XBH A;  4GWM A;  1Y93 A;  1HV5 A;  4GR0 A;  1BM6 A;  4Q1L A;  3KMC A;  1WNI A;  2YIG A;  2L0R A;  4DV8 A;  2DDY A;  3LE9 A;  1SLN A;  1PWW A;  1K7I A;  1XUR A;  1C7K A;  1ZTQ A;  3EDH A;  1C8T A;  1YOU A;  3HY7 A;  5I12 A;  1D8F A;  3HBV P;  3EDZ A;  1BKC A;  5L79 A;  1JKY A;  1KUI A;  1MMR A;  5LAB A;  1PWP A;  1JIW P;  1R54 A;  2ERO A;  1HFS A;  5B5O A;  456C A;  3F1A A;  4QKZ A;  3WV3 A;  1ZP5 A;  4J4M A;  1YCM A;  2D1O A;  1CIZ A;  1JIZ A;  2OXZ A;  2CKI A;  3WV1 A;  1XUD A;  4AUO A;  4JQG A;  1A85 A;  4WF6 A;  1HFC A;  3HBU P;  4FXQ A;  2A8H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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