3CKIA

Crystal structure of the tace-n-timp-3 complex
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
256
structure length
256
Chain Sequence
DPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex.
pubmed doi rcsb
molecule tags Hydrolase, hydrolase inhibitor
source organism Homo sapiens
molecule keywords ADAM 17
total genus 82
structure length 256
sequence length 256
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2008-03-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3ckiA00
3EHXA 1QJJA 1KUIA 3TS4A 4Q1LA 4WZVA 2V4BA 1ZXCA 2ERQA 3Q2HA 2EROA 4AYKA 4GQLA 3O2XA 1XFXA 1BUVM 2OW0A 1ZVXA 1D5JA 1JIWP 1I73A 2WO9A 2W15A 3LE9A 2MLRA 3LIRA 5D1TA 1Z3JA 3L0TA 4G0DA 3OHOA 5I0LA 4H49A 3LJTA 3G5CA 5BOYA 5D1UA 4FU4A 4I03A 4H82A 1XURA 1GE5A 3EDGA 3B92A 4XBHA 1ZXVA 4H84A 5L7FA 4PKUA 4FXYP 966CA 3DPEA 2OW1A 1AF0A 2PJTA 1BZSA 3F15A 1QIAA 2YB9A 1QUAA 3HBUP 2MZHA 1YP1A 1J7NA 5CXAA 4JA1A 2CLTA 4JPAA 1JAPA 3ZVSA 4G9LA 4AXQA 3DWBA 3GBOA 2OY2A 5I2ZA 1SATA 3I7GA 2W13A 4HMAA 5B5PA 4DPEA 4WKEA 3G42A 1JIZA 1FM1A 1JANA 1GKDA 4A7BA 1KUGA 2X3CA 1KUKA 2KRJA 4PKRA 1IACA 2I47A 1CXVA 1BSWA 4ZR5A 5CZMA 2WOAA 1UTZA 2Y6DA 1HFCA 2JIHA 3TVCA 3MA2A 4AIGA 2FV9A 1BKCA 1CIZA 1XFUA 1D8MA 4ILWD 3AIGA 3HBVP 3AYUA 3RTTA 2OXWA 2D1NA 1RM8A 1BM6A 2D1OA 3LJGA 1QIBA 1IAGA 1KBCA 1ND1A 1JH1A 1AYKA 1IABA 2X3AA 3KRYA 2CKIA 3F18A 4GWMA 3CKIA 1K7GA 2SRTA 2OXUA 2W14A 1DTHA 1EB6A 1JKYA 2W0DA 1FLSA 1A86A 1JK3A 3EWJA 1USNA 3RTSA 1MMPA 3WV3A 4GR0A 4CTHA 4DD8A 4HX3A 1C3IA 1G4KA 5LABA 1MNCA 1HOVA 5BPAA 3V96B 3KMEA 2XS3A 2OW9A 1JAQA 3E8RA 5D7WA 2JNPA 3N2UA 4FVLA 1R1HA 1QJIA 2FV5A 3EHYA 1D8FA 2J83A 4DF9A 3HDAP 3K7LA 3KECA 5D1SA 1MMRA 1XFWA 3F19A 4PKSA 2X3BA 2X7MA 2POJA 1SRPA 2ERPA 1R1JA 3HYGA 1CGLA 3ZUKA 3HY9A 3LIKA 1SMPA 1OM8A 1IAEA 2J0TA 1Y93A 4H30A 1AKLA 1PWVA 1A85A 5CUHA 3VTGA 5I4OA 2A8HA 5I3MA 4PKVA 1G05A 1YCMA 3K7NA 5H8XA 1IADA 4L6TA 3DPFA 1H71P 1G12A 1XFVA 3LUMA 2O3EA 830CA 1C8TA 2W12A 4WKIA 5B5OA 3EDHA 4H2EA 1CGFA 3KWVC 1K7QA 1I1IP 3LJZA 2DDYA 1PWQA 4XM8A 1ASTA 3NX7A 1XUDA 1JJ9A 1YOUA 3DNGA 3KEJA 3LMCA 1GO8P 4I35A 2HU6A 3P24A 3KHIA 2O36A 1OS9A 1BIWA 2L0RA 4QKZA 1HV5A 1UMTA 1RMZA 5D3CA 4JP4A 1UMSA 4ON1A 1OMJA 3KMCA 1KUHA 3P1VA 1GE7A 4AUOA 1HTDA 4H76A 1BQOA 1S4BP 1R54A 1PWPA 1UEAA 1Y8JA 1GKCA 4DV8A 4PKTA 1OO9A 4XCTA 2MZEA 1OM6A 2YIGA 3BA0A 1ZP5A 3DL1A 1EUBA 2DW0A 1DMTA 4GR8A 1GXDA 1GE6A 4JIJA 1BUDA 3LUNA 1SU3A 4WF6A 2Z2DA 1SLMA 2K2GA 3L0VA 2JT5A 2K9CA 2TCLA 4JQGA 1CQRA 1ZS0A 3LGPA 3HY7A 1I76A 2Y6CA 5JMYA 1R55A 3WV2A 1EAKA 3HDBA 3LK8A 1ATLA 3LQBA 1XFYA 1B8YA 1FBLA 2OI0A 3Q2GA 1YQYA 4IN9A 3O64A 1G49A 4GF1A 4R3VA 456CA 3SHIA 1UTTA 4GUYA 3ZXHA 1Y0VA 5I12A 1CAQA 1PWWA 2MZIA 3USNA 3LILA 4XM6A 1OS2A 1B3DA 4XM7A 3DSLA 3F1AA 3TSKA 4A3WA 3LKAA 1CK7A 2WO8A 3N2VA 1L6JA 1K7IA 4J4MA 2QPJA 4H3XA 4GR3A 3EDIA 2USNA 3U1RA 4PKQA 1MMQA 1PWUA 3ELMA 5L79A 1XFZA 2OVZA 2RJPA 4WK7A 1HY7A 1BKCI 3F17A 2OW2A 3UVCA 5D2BA 1C7KA 2OY4A 3VI1A 1ROSA 2OVXA 4EFSA 1QICA 1XUCA 3OHLA 2OXZA 3HB2P 1Q3AA 3EDZA 4L63A 1G9KA 3B2ZA 2XS4A 3LEAA 2JT6A 4L19A 2AIGP 3F16A 3B8ZA 1GO7P 3LQ0A 2AYKA 1CGEA 1MMBA 2DW1A 2OZRA 1KUFA 1O0QA 3WV1A 2RJQA 3TT4A 2DDFA 2MLSA 2E3XA 1D7XA 1SLNA 4FXQA 1IAAA 4H1QA 1O0TA 1ZTQA 1BQQM 1KAPP 3KEKA 1BKCE 5I43A 2JSDA 1WNIA 2N8RA 5BOTA 2DW2A 1JAOA 2E2DA 4IUWA 1OM7A 4PKWA 3I7IA 3AYKA 1R1IA 4GWNA 4IJOA 1HFSA
chains in the Genus database with same CATH superfamily
3EHXA 1QJJA 1KUIA 3TS4A 4Q1LA 4WZVA 2V4BA 1ZXCA 2ERQA 3Q2HA 2EROA 4AYKA 4GQLA 3O2XA 1XFXA 1BUVM 2OW0A 1ZVXA 1D5JA 1JIWP 1I73A 2WO9A 2W15A 3LE9A 2MLRA 3LIRA 5D1TA 1Z3JA 3L0TA 4G0DA 3OHOA 5I0LA 4H49A 3LJTA 3G5CA 5BOYA 5D1UA 4FU4A 4I03A 4H82A 1XURA 1GE5A 3EDGA 3B92A 4XBHA 1ZXVA 4H84A 5L7FA 4PKUA 4FXYP 966CA 3DPEA 2OW1A 1AF0A 2PJTA 1BZSA 3F15A 1QIAA 2YB9A 1QUAA 3HBUP 2MZHA 1YP1A 1J7NA 5CXAA 4JA1A 2CLTA 4JPAA 1JAPA 3ZVSA 4G9LA 4AXQA 3DWBA 3GBOA 2OY2A 5I2ZA 1SATA 3I7GA 2W13A 4HMAA 5B5PA 4DPEA 4WKEA 3G42A 1JIZA 1FM1A 3DTIA 1JANA 1GKDA 4A7BA 1KUGA 2X3CA 1KUKA 2KRJA 4PKRA 1IACA 2I47A 1CXVA 1BSWA 4ZR5A 5CZMA 2WOAA 1UTZA 2Y6DA 1HFCA 2JIHA 3TVCA 3MA2A 4AIGA 2FV9A 1BKCA 1CIZA 1XFUA 1D8MA 4ILWD 3AIGA 3HBVP 3AYUA 3RTTA 2OXWA 2D1NA 1RM8A 1BM6A 2D1OA 3LJGA 1QIBA 1IAGA 1KBCA 1ND1A 1JH1A 1AYKA 1IABA 2X3AA 3KRYA 2CKIA 3F18A 4GWMA 3CKIA 1K7GA 2SRTA 2OXUA 2W14A 1DTHA 1EB6A 1JKYA 2W0DA 1FLSA 1A86A 1JK3A 3EWJA 1USNA 3RTSA 1MMPA 3WV3A 3DTEA 4GR0A 4CTHA 4DD8A 4HX3A 1C3IA 1G4KA 5LABA 1MNCA 1HOVA 5BPAA 3V96B 3KMEA 2XS3A 2OW9A 1JAQA 3E8RA 5D7WA 2JNPA 3N2UA 4FVLA 1R1HA 1QJIA 2FV5A 3EHYA 1D8FA 2J83A 4DF9A 3HDAP 1XM5A 3K7LA 3KECA 5D1SA 1MMRA 1XFWA 3F19A 4PKSA 2X3BA 1OZ9A 2X7MA 2POJA 1SRPA 2ERPA 1R1JA 3HYGA 1CGLA 3ZUKA 3HY9A 3LIKA 1SMPA 1OM8A 1IAEA 2J0TA 1Y93A 4H30A 1AKLA 1PWVA 1A85A 5CUHA 3VTGA 5I4OA 2A8HA 5I3MA 4PKVA 1G05A 1YCMA 3K7NA 5H8XA 1XAXA 1IADA 4L6TA 3DPFA 1H71P 1G12A 1XFVA 3LUMA 2O3EA 830CA 1C8TA 2W12A 4WKIA 5B5OA 3EDHA 4H2EA 1CGFA 3KWVC 1K7QA 1I1IP 3LJZA 2DDYA 1PWQA 4XM8A 1ASTA 3NX7A 1XUDA 1JJ9A 1YOUA 3DNGA 3KEJA 3LMCA 1GO8P 4I35A 2HU6A 3P24A 3KHIA 2O36A 1OS9A 1BIWA 2L0RA 4QKZA 1HV5A 1UMTA 1RMZA 5D3CA 4JP4A 1UMSA 4ON1A 1OMJA 3KMCA 1KUHA 3P1VA 1GE7A 4AUOA 1HTDA 4H76A 1BQOA 1S4BP 1R54A 1PWPA 1UEAA 3DTKA 1Y8JA 1GKCA 4DV8A 4PKTA 1OO9A 4XCTA 2MZEA 1OM6A 2YIGA 1TVIA 3BA0A 1ZP5A 3DL1A 1EUBA 2DW0A 1DMTA 4GR8A 1GXDA 1GE6A 4JIJA 4L7AA 1BUDA 3LUNA 1SU3A 4WF6A 2Z2DA 1SLMA 2K2GA 3L0VA 2JT5A 2K9CA 2TCLA 4JQGA 1CQRA 1ZS0A 3LGPA 3HY7A 1I76A 2Y6CA 5JMYA 1R55A 3WV2A 1EAKA 3HDBA 3LK8A 1ATLA 3LQBA 1XFYA 1B8YA 1FBLA 2OI0A 3Q2GA 1YQYA 4IN9A 3O64A 1G49A 4GF1A 4R3VA 456CA 3SHIA 1UTTA 4GUYA 3ZXHA 1Y0VA 5I12A 1CAQA 1PWWA 2MZIA 3USNA 2YUFA 3LILA 4XM6A 1OS2A 1B3DA 4XM7A 3DSLA 3F1AA 3TSKA 4A3WA 3LKAA 1CK7A 2WO8A 3N2VA 1L6JA 1K7IA 4J4MA 2QPJA 4H3XA 4GR3A 3EDIA 2USNA 3U1RA 4PKQA 1MMQA 1PWUA 3ELMA 5L79A 1XFZA 2OVZA 2RJPA 4WK7A 1HY7A 1BKCI 3F17A 2OW2A 3UVCA 5D2BA 1C7KA 2OY4A 3VI1A 1ROSA 2OVXA 4EFSA 1QICA 1XUCA 3OHLA 2OXZA 3HB2P 1Q3AA 3EDZA 4L63A 1G9KA 3B2ZA 2XS4A 3LEAA 2JT6A 4L19A 2AIGP 3F16A 3B8ZA 1GO7P 3LQ0A 2AYKA 1CGEA 1MMBA 2DW1A 2OZRA 1KUFA 1O0QA 3WV1A 2RJQA 3TT4A 2DDFA 2MLSA 2E3XA 1D7XA 1SLNA 4FXQA 1IAAA 4H1QA 1O0TA 1ZTQA 1BQQM 1KAPP 3KEKA 1BKCE 5I43A 2JSDA 1WNIA 2N8RA 5BOTA 2DW2A 1JAOA 2E2DA 4IUWA 1OM7A 4PKWA 3I7IA 3AYKA 1R1IA 4GWNA 4IJOA 1HFSA
chains in the Genus database with same CATH topology
3EHXA 1QJJA 1KUIA 3TS4A 4Q1LA 4WZVA 2V4BA 1ZXCA 2ERQA 3Q2HA 2EROA 4AYKA 4GQLA 3O2XA 1XFXA 1BUVM 2OW0A 1ZVXA 1D5JA 1JIWP 1I73A 2WO9A 2W15A 3LE9A 2MLRA 3LIRA 5D1TA 1Z3JA 3L0TA 4G0DA 3OHOA 5I0LA 4H49A 3LJTA 3G5CA 5BOYA 5D1UA 4FU4A 4I03A 4H82A 1XURA 1GE5A 3EDGA 3B92A 4XBHA 1ZXVA 4H84A 5L7FA 4PKUA 4FXYP 966CA 3DPEA 2OW1A 1AF0A 2PJTA 1BZSA 3F15A 1QIAA 2YB9A 1QUAA 3HBUP 2MZHA 1YP1A 1J7NA 5CXAA 4JA1A 2CLTA 4JPAA 1JAPA 3ZVSA 4G9LA 4AXQA 3DWBA 3GBOA 2OY2A 5I2ZA 1SATA 3I7GA 2W13A 4HMAA 5B5PA 4DPEA 4WKEA 3G42A 1JIZA 1FM1A 3DTIA 1JANA 1GKDA 4A7BA 1KUGA 2X3CA 1KUKA 2KRJA 4PKRA 1IACA 2I47A 1CXVA 1BSWA 4ZR5A 5CZMA 2WOAA 1UTZA 2Y6DA 1HFCA 2JIHA 3TVCA 3MA2A 4AIGA 2FV9A 1BKCA 1CIZA 1XFUA 1D8MA 4ILWD 3AIGA 3HBVP 3AYUA 3RTTA 2OXWA 2D1NA 1RM8A 1BM6A 2D1OA 3LJGA 1QIBA 1IAGA 1KBCA 1ND1A 1JH1A 1AYKA 1IABA 2X3AA 3KRYA 2CKIA 3F18A 4GWMA 3CKIA 1K7GA 2SRTA 2OXUA 2W14A 1DTHA 1EB6A 1JKYA 2W0DA 1FLSA 1A86A 1JK3A 3EWJA 1USNA 3RTSA 1MMPA 3WV3A 3DTEA 4GR0A 4CTHA 4DD8A 4HX3A 1C3IA 1G4KA 5LABA 1MNCA 1HOVA 5BPAA 3V96B 3KMEA 2XS3A 2OW9A 1JAQA 3E8RA 5D7WA 2JNPA 3N2UA 4FVLA 1R1HA 1QJIA 2FV5A 3EHYA 1D8FA 2J83A 4DF9A 3HDAP 3K7LA 3KECA 5D1SA 1MMRA 1XFWA 3F19A 4PKSA 2X3BA 2X7MA 2POJA 1SRPA 2ERPA 1R1JA 3HYGA 1CGLA 3ZUKA 3HY9A 3LIKA 1SMPA 1OM8A 1IAEA 2J0TA 1Y93A 4H30A 1AKLA 1PWVA 1A85A 5CUHA 3VTGA 5I4OA 2A8HA 5I3MA 4PKVA 1G05A 1YCMA 3K7NA 5H8XA 1IADA 4L6TA 3DPFA 1H71P 1G12A 1XFVA 3LUMA 2O3EA 830CA 1C8TA 2W12A 4WKIA 5B5OA 3EDHA 4H2EA 1CGFA 3KWVC 1K7QA 1I1IP 3LJZA 2DDYA 1PWQA 4XM8A 1ASTA 3NX7A 1XUDA 1JJ9A 1YOUA 3DNGA 3KEJA 3LMCA 1GO8P 4I35A 2HU6A 3P24A 3KHIA 2O36A 1OS9A 1BIWA 2L0RA 4QKZA 1HV5A 1UMTA 1RMZA 5D3CA 4JP4A 1UMSA 4ON1A 1OMJA 3KMCA 1KUHA 3P1VA 1GE7A 4AUOA 1HTDA 4H76A 1BQOA 1S4BP 1R54A 1PWPA 1UEAA 3DTKA 1Y8JA 1GKCA 4DV8A 4PKTA 1OO9A 4XCTA 2MZEA 1OM6A 2YIGA 3BA0A 1ZP5A 3DL1A 1EUBA 2DW0A 1DMTA 4GR8A 1GXDA 1GE6A 4JIJA 4L7AA 1BUDA 3LUNA 1SU3A 4WF6A 2Z2DA 1SLMA 2K2GA 3L0VA 2JT5A 2K9CA 2TCLA 4JQGA 1CQRA 1ZS0A 3LGPA 3HY7A 1I76A 2Y6CA 5JMYA 1R55A 3WV2A 1EAKA 3HDBA 3LK8A 1ATLA 3LQBA 1XFYA 1B8YA 1FBLA 2OI0A 3Q2GA 1YQYA 4IN9A 3O64A 1G49A 4GF1A 4R3VA 456CA 3SHIA 1UTTA 4GUYA 3ZXHA 1Y0VA 5I12A 1CAQA 1PWWA 2MZIA 3USNA 2YUFA 3LILA 4XM6A 1OS2A 1B3DA 4XM7A 3DSLA 3F1AA 3TSKA 4A3WA 3LKAA 1CK7A 2WO8A 3N2VA 1L6JA 1K7IA 4J4MA 2QPJA 4H3XA 4GR3A 3EDIA 2USNA 3U1RA 4PKQA 1MMQA 1PWUA 3ELMA 5L79A 1XFZA 2OVZA 2RJPA 4WK7A 1HY7A 1BKCI 3F17A 2OW2A 3UVCA 5D2BA 1C7KA 2OY4A 3VI1A 1ROSA 2OVXA 4EFSA 1QICA 1XUCA 3OHLA 2OXZA 3HB2P 1Q3AA 3EDZA 4L63A 1G9KA 3B2ZA 2XS4A 3LEAA 2JT6A 4L19A 2AIGP 3F16A 3B8ZA 1GO7P 3LQ0A 2AYKA 1CGEA 1MMBA 2DW1A 2OZRA 1KUFA 1O0QA 3WV1A 2RJQA 3TT4A 2DDFA 2MLSA 2E3XA 1D7XA 1SLNA 4FXQA 1IAAA 4H1QA 1O0TA 1ZTQA 1BQQM 1KAPP 3KEKA 1BKCE 5I43A 2JSDA 1WNIA 2N8RA 5BOTA 2DW2A 1JAOA 2E2DA 4IUWA 1OM7A 4PKWA 3I7IA 3AYKA 1R1IA 4GWNA 4IJOA 1HFSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EHX A;  1QJJ A;  1KUI A;  3TS4 A;  4Q1L A;  4WZV A;  2V4B A;  1ZXC A;  2ERQ A;  3Q2H A;  2ERO A;  4AYK A;  4GQL A;  3O2X A;  1XFX A;  1BUV M;  2OW0 A;  1ZVX A;  1D5J A;  1JIW P;  1I73 A;  2WO9 A;  2W15 A;  3LE9 A;  2MLR A;  3LIR A;  5D1T A;  1Z3J A;  3L0T A;  4G0D A;  3OHO A;  5I0L A;  4H49 A;  3LJT A;  3G5C A;  5BOY A;  5D1U A;  4FU4 A;  4I03 A;  4H82 A;  1XUR A;  1GE5 A;  3EDG A;  3B92 A;  4XBH A;  1ZXV A;  4H84 A;  5L7F A;  4PKU A;  4FXY P;  966C A;  3DPE A;  2OW1 A;  1AF0 A;  2PJT A;  1BZS A;  3F15 A;  1QIA A;  2YB9 A;  1QUA A;  3HBU P;  2MZH A;  1YP1 A;  1J7N A;  5CXA A;  4JA1 A;  2CLT A;  4JPA A;  1JAP A;  3ZVS A;  4G9L A;  4AXQ A;  3DWB A;  3GBO A;  2OY2 A;  5I2Z A;  1SAT A;  3I7G A;  2W13 A;  4HMA A;  5B5P A;  4DPE A;  4WKE A;  3G42 A;  1JIZ A;  1FM1 A;  1JAN A;  1GKD A;  4A7B A;  1KUG A;  2X3C A;  1KUK A;  2KRJ A;  4PKR A;  1IAC A;  2I47 A;  1CXV A;  1BSW A;  4ZR5 A;  5CZM A;  2WOA A;  1UTZ A;  2Y6D A;  1HFC A;  2JIH A;  3TVC A;  3MA2 A;  4AIG A;  2FV9 A;  1BKC A;  1CIZ A;  1XFU A;  1D8M A;  4ILW D;  3AIG A;  3HBV P;  3AYU A;  3RTT A;  2OXW A;  2D1N A;  1RM8 A;  1BM6 A;  2D1O A;  3LJG A;  1QIB A;  1IAG A;  1KBC A;  1ND1 A;  1JH1 A;  1AYK A;  1IAB A;  2X3A A;  3KRY A;  2CKI A;  3F18 A;  4GWM A;  3CKI A;  1K7G A;  2SRT A;  2OXU A;  2W14 A;  1DTH A;  1EB6 A;  1JKY A;  2W0D A;  1FLS A;  1A86 A;  1JK3 A;  3EWJ A;  1USN A;  3RTS A;  1MMP A;  3WV3 A;  4GR0 A;  4CTH A;  4DD8 A;  4HX3 A;  1C3I A;  1G4K A;  5LAB A;  1MNC A;  1HOV A;  5BPA A;  3V96 B;  3KME A;  2XS3 A;  2OW9 A;  1JAQ A;  3E8R A;  5D7W A;  2JNP A;  3N2U A;  4FVL A;  1R1H A;  1QJI A;  2FV5 A;  3EHY A;  1D8F A;  2J83 A;  4DF9 A;  3HDA P;  3K7L A;  3KEC A;  5D1S A;  1MMR A;  1XFW A;  3F19 A;  4PKS A;  2X3B A;  2X7M A;  2POJ A;  1SRP A;  2ERP A;  1R1J A;  3HYG A;  1CGL A;  3ZUK A;  3HY9 A;  3LIK A;  1SMP A;  1OM8 A;  1IAE A;  2J0T A;  1Y93 A;  4H30 A;  1AKL A;  1PWV A;  1A85 A;  5CUH A;  3VTG A;  5I4O A;  2A8H A;  5I3M A;  4PKV A;  1G05 A;  1YCM A;  3K7N A;  5H8X A;  1IAD A;  4L6T A;  3DPF A;  1H71 P;  1G12 A;  1XFV A;  3LUM A;  2O3E A;  830C A;  1C8T A;  2W12 A;  4WKI A;  5B5O A;  3EDH A;  4H2E A;  1CGF A;  3KWV C;  1K7Q A;  1I1I P;  3LJZ A;  2DDY A;  1PWQ A;  4XM8 A;  1AST A;  3NX7 A;  1XUD A;  1JJ9 A;  1YOU A;  3DNG A;  3KEJ A;  3LMC A;  1GO8 P;  4I35 A;  2HU6 A;  3P24 A;  3KHI A;  2O36 A;  1OS9 A;  1BIW A;  2L0R A;  4QKZ A;  1HV5 A;  1UMT A;  1RMZ A;  5D3C A;  4JP4 A;  1UMS A;  4ON1 A;  1OMJ A;  3KMC A;  1KUH A;  3P1V A;  1GE7 A;  4AUO A;  1HTD A;  4H76 A;  1BQO A;  1S4B P;  1R54 A;  1PWP A;  1UEA A;  1Y8J A;  1GKC A;  4DV8 A;  4PKT A;  1OO9 A;  4XCT A;  2MZE A;  1OM6 A;  2YIG A;  3BA0 A;  1ZP5 A;  3DL1 A;  1EUB A;  2DW0 A;  1DMT A;  4GR8 A;  1GXD A;  1GE6 A;  4JIJ A;  1BUD A;  3LUN A;  1SU3 A;  4WF6 A;  2Z2D A;  1SLM A;  2K2G A;  3L0V A;  2JT5 A;  2K9C A;  2TCL A;  4JQG A;  1CQR A;  1ZS0 A;  3LGP A;  3HY7 A;  1I76 A;  2Y6C A;  5JMY A;  1R55 A;  3WV2 A;  1EAK A;  3HDB A;  3LK8 A;  1ATL A;  3LQB A;  1XFY A;  1B8Y A;  1FBL A;  2OI0 A;  3Q2G A;  1YQY A;  4IN9 A;  3O64 A;  1G49 A;  4GF1 A;  4R3V A;  456C A;  3SHI A;  1UTT A;  4GUY A;  3ZXH A;  1Y0V A;  5I12 A;  1CAQ A;  1PWW A;  2MZI A;  3USN A;  3LIL A;  4XM6 A;  1OS2 A;  1B3D A;  4XM7 A;  3DSL A;  3F1A A;  3TSK A;  4A3W A;  3LKA A;  1CK7 A;  2WO8 A;  3N2V A;  1L6J A;  1K7I A;  4J4M A;  2QPJ A;  4H3X A;  4GR3 A;  3EDI A;  2USN A;  3U1R A;  4PKQ A;  1MMQ A;  1PWU A;  3ELM A;  5L79 A;  1XFZ A;  2OVZ A;  2RJP A;  4WK7 A;  1HY7 A;  1BKC I;  3F17 A;  2OW2 A;  3UVC A;  5D2B A;  1C7K A;  2OY4 A;  3VI1 A;  1ROS A;  2OVX A;  4EFS A;  1QIC A;  1XUC A;  3OHL A;  2OXZ A;  3HB2 P;  1Q3A A;  3EDZ A;  4L63 A;  1G9K A;  3B2Z A;  2XS4 A;  3LEA A;  2JT6 A;  4L19 A;  2AIG P;  3F16 A;  3B8Z A;  1GO7 P;  3LQ0 A;  2AYK A;  1CGE A;  1MMB A;  2DW1 A;  2OZR A;  1KUF A;  1O0Q A;  3WV1 A;  2RJQ A;  3TT4 A;  2DDF A;  2MLS A;  2E3X A;  1D7X A;  1SLN A;  4FXQ A;  1IAA A;  4H1Q A;  1O0T A;  1ZTQ A;  1BQQ M;  1KAP P;  3KEK A;  1BKC E;  5I43 A;  2JSD A;  1WNI A;  2N8R A;  5BOT A;  2DW2 A;  1JAO A;  2E2D A;  4IUW A;  1OM7 A;  4PKW A;  3I7I A;  3AYK A;  1R1I A;  4GWN A;  4IJO A;  1HFS A; 
#chains in the Genus database with same CATH topology
 3EHX A;  1QJJ A;  1KUI A;  3TS4 A;  4Q1L A;  4WZV A;  2V4B A;  1ZXC A;  2ERQ A;  3Q2H A;  2ERO A;  4AYK A;  4GQL A;  3O2X A;  1XFX A;  1BUV M;  2OW0 A;  1ZVX A;  1D5J A;  1JIW P;  1I73 A;  2WO9 A;  2W15 A;  3LE9 A;  2MLR A;  3LIR A;  5D1T A;  1Z3J A;  3L0T A;  4G0D A;  3OHO A;  5I0L A;  4H49 A;  3LJT A;  3G5C A;  5BOY A;  5D1U A;  4FU4 A;  4I03 A;  4H82 A;  1XUR A;  1GE5 A;  3EDG A;  3B92 A;  4XBH A;  1ZXV A;  4H84 A;  5L7F A;  4PKU A;  4FXY P;  966C A;  3DPE A;  2OW1 A;  1AF0 A;  2PJT A;  1BZS A;  3F15 A;  1QIA A;  2YB9 A;  1QUA A;  3HBU P;  2MZH A;  1YP1 A;  1J7N A;  5CXA A;  4JA1 A;  2CLT A;  4JPA A;  1JAP A;  3ZVS A;  4G9L A;  4AXQ A;  3DWB A;  3GBO A;  2OY2 A;  5I2Z A;  1SAT A;  3I7G A;  2W13 A;  4HMA A;  5B5P A;  4DPE A;  4WKE A;  3G42 A;  1JIZ A;  1FM1 A;  3DTI A;  1JAN A;  1GKD A;  4A7B A;  1KUG A;  2X3C A;  1KUK A;  2KRJ A;  4PKR A;  1IAC A;  2I47 A;  1CXV A;  1BSW A;  4ZR5 A;  5CZM A;  2WOA A;  1UTZ A;  2Y6D A;  1HFC A;  2JIH A;  3TVC A;  3MA2 A;  4AIG A;  2FV9 A;  1BKC A;  1CIZ A;  1XFU A;  1D8M A;  4ILW D;  3AIG A;  3HBV P;  3AYU A;  3RTT A;  2OXW A;  2D1N A;  1RM8 A;  1BM6 A;  2D1O A;  3LJG A;  1QIB A;  1IAG A;  1KBC A;  1ND1 A;  1JH1 A;  1AYK A;  1IAB A;  2X3A A;  3KRY A;  2CKI A;  3F18 A;  4GWM A;  3CKI A;  1K7G A;  2SRT A;  2OXU A;  2W14 A;  1DTH A;  1EB6 A;  1JKY A;  2W0D A;  1FLS A;  1A86 A;  1JK3 A;  3EWJ A;  1USN A;  3RTS A;  1MMP A;  3WV3 A;  3DTE A;  4GR0 A;  4CTH A;  4DD8 A;  4HX3 A;  1C3I A;  1G4K A;  5LAB A;  1MNC A;  1HOV A;  5BPA A;  3V96 B;  3KME A;  2XS3 A;  2OW9 A;  1JAQ A;  3E8R A;  5D7W A;  2JNP A;  3N2U A;  4FVL A;  1R1H A;  1QJI A;  2FV5 A;  3EHY A;  1D8F A;  2J83 A;  4DF9 A;  3HDA P;  1XM5 A;  3K7L A;  3KEC A;  5D1S A;  1MMR A;  1XFW A;  3F19 A;  4PKS A;  2X3B A;  1OZ9 A;  2X7M A;  2POJ A;  1SRP A;  2ERP A;  1R1J A;  3HYG A;  1CGL A;  3ZUK A;  3HY9 A;  3LIK A;  1SMP A;  1OM8 A;  1IAE A;  2J0T A;  1Y93 A;  4H30 A;  1AKL A;  1PWV A;  1A85 A;  5CUH A;  3VTG A;  5I4O A;  2A8H A;  5I3M A;  4PKV A;  1G05 A;  1YCM A;  3K7N A;  5H8X A;  1XAX A;  1IAD A;  4L6T A;  3DPF A;  1H71 P;  1G12 A;  1XFV A;  3LUM A;  2O3E A;  830C A;  1C8T A;  2W12 A;  4WKI A;  5B5O A;  3EDH A;  4H2E A;  1CGF A;  3KWV C;  1K7Q A;  1I1I P;  3LJZ A;  2DDY A;  1PWQ A;  4XM8 A;  1AST A;  3NX7 A;  1XUD A;  1JJ9 A;  1YOU A;  3DNG A;  3KEJ A;  3LMC A;  1GO8 P;  4I35 A;  2HU6 A;  3P24 A;  3KHI A;  2O36 A;  1OS9 A;  1BIW A;  2L0R A;  4QKZ A;  1HV5 A;  1UMT A;  1RMZ A;  5D3C A;  4JP4 A;  1UMS A;  4ON1 A;  1OMJ A;  3KMC A;  1KUH A;  3P1V A;  1GE7 A;  4AUO A;  1HTD A;  4H76 A;  1BQO A;  1S4B P;  1R54 A;  1PWP A;  1UEA A;  3DTK A;  1Y8J A;  1GKC A;  4DV8 A;  4PKT A;  1OO9 A;  4XCT A;  2MZE A;  1OM6 A;  2YIG A;  1TVI A;  3BA0 A;  1ZP5 A;  3DL1 A;  1EUB A;  2DW0 A;  1DMT A;  4GR8 A;  1GXD A;  1GE6 A;  4JIJ A;  4L7A A;  1BUD A;  3LUN A;  1SU3 A;  4WF6 A;  2Z2D A;  1SLM A;  2K2G A;  3L0V A;  2JT5 A;  2K9C A;  2TCL A;  4JQG A;  1CQR A;  1ZS0 A;  3LGP A;  3HY7 A;  1I76 A;  2Y6C A;  5JMY A;  1R55 A;  3WV2 A;  1EAK A;  3HDB A;  3LK8 A;  1ATL A;  3LQB A;  1XFY A;  1B8Y A;  1FBL A;  2OI0 A;  3Q2G A;  1YQY A;  4IN9 A;  3O64 A;  1G49 A;  4GF1 A;  4R3V A;  456C A;  3SHI A;  1UTT A;  4GUY A;  3ZXH A;  1Y0V A;  5I12 A;  1CAQ A;  1PWW A;  2MZI A;  3USN A;  2YUF A;  3LIL A;  4XM6 A;  1OS2 A;  1B3D A;  4XM7 A;  3DSL A;  3F1A A;  3TSK A;  4A3W A;  3LKA A;  1CK7 A;  2WO8 A;  3N2V A;  1L6J A;  1K7I A;  4J4M A;  2QPJ A;  4H3X A;  4GR3 A;  3EDI A;  2USN A;  3U1R A;  4PKQ A;  1MMQ A;  1PWU A;  3ELM A;  5L79 A;  1XFZ A;  2OVZ A;  2RJP A;  4WK7 A;  1HY7 A;  1BKC I;  3F17 A;  2OW2 A;  3UVC A;  5D2B A;  1C7K A;  2OY4 A;  3VI1 A;  1ROS A;  2OVX A;  4EFS A;  1QIC A;  1XUC A;  3OHL A;  2OXZ A;  3HB2 P;  1Q3A A;  3EDZ A;  4L63 A;  1G9K A;  3B2Z A;  2XS4 A;  3LEA A;  2JT6 A;  4L19 A;  2AIG P;  3F16 A;  3B8Z A;  1GO7 P;  3LQ0 A;  2AYK A;  1CGE A;  1MMB A;  2DW1 A;  2OZR A;  1KUF A;  1O0Q A;  3WV1 A;  2RJQ A;  3TT4 A;  2DDF A;  2MLS A;  2E3X A;  1D7X A;  1SLN A;  4FXQ A;  1IAA A;  4H1Q A;  1O0T A;  1ZTQ A;  1BQQ M;  1KAP P;  3KEK A;  1BKC E;  5I43 A;  2JSD A;  1WNI A;  2N8R A;  5BOT A;  2DW2 A;  1JAO A;  2E2D A;  4IUW A;  1OM7 A;  4PKW A;  3I7I A;  3AYK A;  1R1I A;  4GWN A;  4IJO A;  1HFS A; 
#chains in the Genus database with same CATH homology
 3EHX A;  1QJJ A;  1KUI A;  3TS4 A;  4Q1L A;  4WZV A;  2V4B A;  1ZXC A;  2ERQ A;  3Q2H A;  2ERO A;  4AYK A;  4GQL A;  3O2X A;  1XFX A;  1BUV M;  2OW0 A;  1ZVX A;  1D5J A;  1JIW P;  1I73 A;  2WO9 A;  2W15 A;  3LE9 A;  2MLR A;  3LIR A;  5D1T A;  1Z3J A;  3L0T A;  4G0D A;  3OHO A;  5I0L A;  4H49 A;  3LJT A;  3G5C A;  5BOY A;  5D1U A;  4FU4 A;  4I03 A;  4H82 A;  1XUR A;  1GE5 A;  3EDG A;  3B92 A;  4XBH A;  1ZXV A;  4H84 A;  5L7F A;  4PKU A;  4FXY P;  966C A;  3DPE A;  2OW1 A;  1AF0 A;  2PJT A;  1BZS A;  3F15 A;  1QIA A;  2YB9 A;  1QUA A;  3HBU P;  2MZH A;  1YP1 A;  1J7N A;  5CXA A;  4JA1 A;  2CLT A;  4JPA A;  1JAP A;  3ZVS A;  4G9L A;  4AXQ A;  3DWB A;  3GBO A;  2OY2 A;  5I2Z A;  1SAT A;  3I7G A;  2W13 A;  4HMA A;  5B5P A;  4DPE A;  4WKE A;  3G42 A;  1JIZ A;  1FM1 A;  3DTI A;  1JAN A;  1GKD A;  4A7B A;  1KUG A;  2X3C A;  1KUK A;  2KRJ A;  4PKR A;  1IAC A;  2I47 A;  1CXV A;  1BSW A;  4ZR5 A;  5CZM A;  2WOA A;  1UTZ A;  2Y6D A;  1HFC A;  2JIH A;  3TVC A;  3MA2 A;  4AIG A;  2FV9 A;  1BKC A;  1CIZ A;  1XFU A;  1D8M A;  4ILW D;  3AIG A;  3HBV P;  3AYU A;  3RTT A;  2OXW A;  2D1N A;  1RM8 A;  1BM6 A;  2D1O A;  3LJG A;  1QIB A;  1IAG A;  1KBC A;  1ND1 A;  1JH1 A;  1AYK A;  1IAB A;  2X3A A;  3KRY A;  2CKI A;  3F18 A;  4GWM A;  3CKI A;  1K7G A;  2SRT A;  2OXU A;  2W14 A;  1DTH A;  1EB6 A;  1JKY A;  2W0D A;  1FLS A;  1A86 A;  1JK3 A;  3EWJ A;  1USN A;  3RTS A;  1MMP A;  3WV3 A;  3DTE A;  4GR0 A;  4CTH A;  4DD8 A;  4HX3 A;  1C3I A;  1G4K A;  5LAB A;  1MNC A;  1HOV A;  5BPA A;  3V96 B;  3KME A;  2XS3 A;  2OW9 A;  1JAQ A;  3E8R A;  5D7W A;  2JNP A;  3N2U A;  4FVL A;  1R1H A;  1QJI A;  2FV5 A;  3EHY A;  1D8F A;  2J83 A;  4DF9 A;  3HDA P;  3K7L A;  3KEC A;  5D1S A;  1MMR A;  1XFW A;  3F19 A;  4PKS A;  2X3B A;  2X7M A;  2POJ A;  1SRP A;  2ERP A;  1R1J A;  3HYG A;  1CGL A;  3ZUK A;  3HY9 A;  3LIK A;  1SMP A;  1OM8 A;  1IAE A;  2J0T A;  1Y93 A;  4H30 A;  1AKL A;  1PWV A;  1A85 A;  5CUH A;  3VTG A;  5I4O A;  2A8H A;  5I3M A;  4PKV A;  1G05 A;  1YCM A;  3K7N A;  5H8X A;  1IAD A;  4L6T A;  3DPF A;  1H71 P;  1G12 A;  1XFV A;  3LUM A;  2O3E A;  830C A;  1C8T A;  2W12 A;  4WKI A;  5B5O A;  3EDH A;  4H2E A;  1CGF A;  3KWV C;  1K7Q A;  1I1I P;  3LJZ A;  2DDY A;  1PWQ A;  4XM8 A;  1AST A;  3NX7 A;  1XUD A;  1JJ9 A;  1YOU A;  3DNG A;  3KEJ A;  3LMC A;  1GO8 P;  4I35 A;  2HU6 A;  3P24 A;  3KHI A;  2O36 A;  1OS9 A;  1BIW A;  2L0R A;  4QKZ A;  1HV5 A;  1UMT A;  1RMZ A;  5D3C A;  4JP4 A;  1UMS A;  4ON1 A;  1OMJ A;  3KMC A;  1KUH A;  3P1V A;  1GE7 A;  4AUO A;  1HTD A;  4H76 A;  1BQO A;  1S4B P;  1R54 A;  1PWP A;  1UEA A;  3DTK A;  1Y8J A;  1GKC A;  4DV8 A;  4PKT A;  1OO9 A;  4XCT A;  2MZE A;  1OM6 A;  2YIG A;  3BA0 A;  1ZP5 A;  3DL1 A;  1EUB A;  2DW0 A;  1DMT A;  4GR8 A;  1GXD A;  1GE6 A;  4JIJ A;  4L7A A;  1BUD A;  3LUN A;  1SU3 A;  4WF6 A;  2Z2D A;  1SLM A;  2K2G A;  3L0V A;  2JT5 A;  2K9C A;  2TCL A;  4JQG A;  1CQR A;  1ZS0 A;  3LGP A;  3HY7 A;  1I76 A;  2Y6C A;  5JMY A;  1R55 A;  3WV2 A;  1EAK A;  3HDB A;  3LK8 A;  1ATL A;  3LQB A;  1XFY A;  1B8Y A;  1FBL A;  2OI0 A;  3Q2G A;  1YQY A;  4IN9 A;  3O64 A;  1G49 A;  4GF1 A;  4R3V A;  456C A;  3SHI A;  1UTT A;  4GUY A;  3ZXH A;  1Y0V A;  5I12 A;  1CAQ A;  1PWW A;  2MZI A;  3USN A;  2YUF A;  3LIL A;  4XM6 A;  1OS2 A;  1B3D A;  4XM7 A;  3DSL A;  3F1A A;  3TSK A;  4A3W A;  3LKA A;  1CK7 A;  2WO8 A;  3N2V A;  1L6J A;  1K7I A;  4J4M A;  2QPJ A;  4H3X A;  4GR3 A;  3EDI A;  2USN A;  3U1R A;  4PKQ A;  1MMQ A;  1PWU A;  3ELM A;  5L79 A;  1XFZ A;  2OVZ A;  2RJP A;  4WK7 A;  1HY7 A;  1BKC I;  3F17 A;  2OW2 A;  3UVC A;  5D2B A;  1C7K A;  2OY4 A;  3VI1 A;  1ROS A;  2OVX A;  4EFS A;  1QIC A;  1XUC A;  3OHL A;  2OXZ A;  3HB2 P;  1Q3A A;  3EDZ A;  4L63 A;  1G9K A;  3B2Z A;  2XS4 A;  3LEA A;  2JT6 A;  4L19 A;  2AIG P;  3F16 A;  3B8Z A;  1GO7 P;  3LQ0 A;  2AYK A;  1CGE A;  1MMB A;  2DW1 A;  2OZR A;  1KUF A;  1O0Q A;  3WV1 A;  2RJQ A;  3TT4 A;  2DDF A;  2MLS A;  2E3X A;  1D7X A;  1SLN A;  4FXQ A;  1IAA A;  4H1Q A;  1O0T A;  1ZTQ A;  1BQQ M;  1KAP P;  3KEK A;  1BKC E;  5I43 A;  2JSD A;  1WNI A;  2N8R A;  5BOT A;  2DW2 A;  1JAO A;  2E2D A;  4IUW A;  1OM7 A;  4PKW A;  3I7I A;  3AYK A;  1R1I A;  4GWN A;  4IJO A;  1HFS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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