2OZRA

Mmp13 catalytic domain complexed with 4-{[1-methyl-2,4-dioxo-6-(3-phenylprop-1-yn-1-yl)-1,4-dihydroquinazolin-3(2h)-yl]methyl}benzoic acid
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
167
structure length
167
Chain Sequence
b'YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGD'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Collagenase 3
publication title Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 47
structure length 167
sequence length 167
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 3.4.24.-:
pdb deposition date 2007-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2ozrA00
1CIZA 3Q2GA 4IJOA 5I4OA 1JKYA 3MA2A 2W0DA 3VTGA 4WK7A 3DNGA 5LABA 1Y93A 2RJQA 1XUCA 4L19A 3HB2P 3HY9A 1Y8JA 3KMEA 3P24A 3LJTA 1KUFA 5H8XA 1G12A 1ZVXA 3OHLA 1UEAA 3TT4A 2OI0A 5D3CA 3DWBA 1ROSA 3N2UA 1YQYA 5I0LA 4GQLA 2OW0A 3N2VA 4WF6A 1ZS0A 1HOVA 1A85A 2JSDA 4FU4A 1MMRA 1BKCA 3EHXA 3LE9A 1K7QA 4ON1A 1QUAA 2O36A 4ZR5A 1UTZA 4GR8A 1SLNA 1K7IA 1PWQA 2OXUA 4PKWA 5CUHA 1BKCI 4H2EA 1JAPA 4I03A 1RMZA 2XS3A 4PKVA 2JT5A 1K7GA 1B8YA 5D1TA 4IN9A 4Q1LA 2USNA 2DW0A 3LJGA 2EROA 1SU3A 4A7BA 1B3DA 4JA1A 1DMTA 1GE6A 3Q2HA 4G9LA 1BQQM 3ELMA 2W13A 1OM7A 1S4BP 5I3MA 3B8ZA 1KUHA 3AYKA 1SATA 2D1OA 2ERPA 2FV9A 4GWNA 1JH1A 1BSWA 2E2DA 2OY4A 4GF1A 4DPEA 1I73A 4WZVA 2O3EA 1MNCA 3L0VA 1AYKA 2OVZA 4GR0A 3U1RA 3LMCA 4I35A 1ASTA 1JANA 1R1HA 3WV2A 1FLSA 3HBVP 2X3CA 3LGPA 3LQ0A 4WKIA 5BPAA 5D7WA 1HFSA 5I12A 2X7MA 2J0TA 2TCLA 1G4KA 5D1SA 3TVCA 1OS9A 3HDAP 2MLRA 4DD8A 3P1VA 1XFXA 3KHIA 1UMTA 4GWMA 3RTTA 4AXQA 1XFYA 1C7KA 1BUDA 2JIHA 1UMSA 4R3VA 1OO9A 1HY7A 1OM6A 1XFWA 1G9KA 3HY7A 1XURA 1Y0VA 2OY2A 2W15A 1SMPA 3AIGA 5CZMA 2K2GA 4FVLA 1CK7A 1R1JA 3ZVSA 2DW1A 1PWPA 1D8MA 3EDHA 1C8TA 5D1UA 1BQOA 4PKSA 3KWVC 2J83A 1JAQA 3NX7A 1CXVA 1BZSA 4H1QA 3SHIA 1GE5A 1ND1A 1EUBA 3V96B 2MZIA 2POJA 3O64A 2A8HA 1GO7P 3DPEA 1GXDA 4H30A 456CA 4AYKA 2E3XA 3LQBA 1YCMA 3LIRA 2QPJA 1UTTA 1KBCA 4PKQA 3KEKA 1I1IP 1BM6A 2X3BA 4EFSA 1PWWA 2MZEA 3O2XA 1I76A 1QJIA 1GKDA 2DDYA 3WV3A 1EAKA 2OXWA 1AF0A 2OW9A 1KUKA 3EWJA 3L0TA 3EDGA 2N8RA 1MMQA 3F19A 1CAQA 3ZUKA 2AYKA 3LK8A 4WKEA 1D8FA 4H3XA 1IAAA 2WO9A 3OHOA 5I43A 1ATLA 3HDBA 4J4MA 1RM8A 3EDIA 1R54A 4PKTA 1J7NA 1BKCE 1O0QA 5L79A 3VI1A 2DW2A 1KAPP 3BA0A 830CA 3KECA 4HMAA 4H82A 3TS4A 4GUYA 1BUVM 1QIBA 2HU6A 4QKZA 2CLTA 3F18A 5L7FA 1DTHA 1OS2A 2MZHA 1D5JA 2OW1A 4H76A 1FBLA 1EB6A 1XUDA 2XS4A 1ZXCA 4DF9A 1GE7A 3LILA 3F17A 5BOTA 1CGLA 3DPFA 1JIZA 2KRJA 966CA 1JIWP 2PJTA 2DDFA 3LUMA 4XCTA 1AKLA 2V4BA 2JT6A 3EHYA 1ZTQA 5JMYA 4L63A 1WNIA 1QJJA 3UVCA 1USNA 1H71P 2RJPA 1G05A 3RTSA 3B92A 1XFUA 1ZXVA 2Z2DA 1GO8P 2Y6DA 2YB9A 3F1AA 2OW2A 4XM8A 1IACA 4JPAA 2W12A 1IABA 3USNA 1KUGA 1MMBA 3F16A 1SLMA 1C3IA 1PWUA 1OMJA 3AYUA 4IUWA 3KRYA 3WV1A 1CQRA 2K9CA 3K7LA 4XBHA 5B5OA 2YIGA 3LEAA 2WOAA 1HFCA 4GR3A 4JP4A 3LUNA 1Q3AA 4DV8A 3E8RA 1D7XA 3DSLA 1O0TA 3B2ZA 3LIKA 1XFVA 2FV5A 3HBUP 4AUOA 3F15A 2ERQA 2WO8A 1IAEA 3TSKA 5D2BA 3KEJA 1HV5A 2L0RA 3I7IA 5B5PA 4CTHA 4FXYP 3HYGA 1YOUA 3G42A 2OZRA 3I7GA 1PWVA 3KMCA 3G5CA 4FXQA 2Y6CA 1G49A 1Z3JA 2W14A 1JK3A 1QICA 1BIWA 1OM8A 3GBOA 1HTDA 2SRTA 1JJ9A 5I2ZA 2AIGP 1IAGA 4HX3A 2OVXA 1FM1A 1R55A 1MMPA 4G0DA 5CXAA 1CGFA 4PKRA 3LJZA 2CKIA 1SRPA 1ZP5A 1IADA 4L6TA 3LKAA 4H84A 1JAOA 1QIAA 2I47A 1CGEA 4XM7A 1KUIA 4JQGA 3DL1A 2OXZA 1A86A 2JNPA 5BOYA 1YP1A 1R1IA 4H49A 4XM6A 1GKCA 3ZXHA 3CKIA 4AIGA 4ILWD 4PKUA 4A3WA 2D1NA 2X3AA 3K7NA 2MLSA 4JIJA 3EDZA 1L6JA 1XFZA
chains in the Genus database with same CATH superfamily
1CIZA 3Q2GA 4IJOA 5I4OA 1JKYA 3MA2A 2W0DA 3VTGA 4WK7A 3DNGA 5LABA 1Y93A 2RJQA 1XUCA 4L19A 3HB2P 3HY9A 1Y8JA 3KMEA 3P24A 3LJTA 1KUFA 5H8XA 1G12A 1ZVXA 3OHLA 1UEAA 3TT4A 2OI0A 5D3CA 3DWBA 1ROSA 3N2UA 1YQYA 5I0LA 4GQLA 2OW0A 3N2VA 4WF6A 1ZS0A 3DTEA 1A85A 2JSDA 1HOVA 4FU4A 1MMRA 1BKCA 3EHXA 3LE9A 1K7QA 4ON1A 1QUAA 2O36A 4ZR5A 1UTZA 4GR8A 1SLNA 1K7IA 1PWQA 2OXUA 4PKWA 5CUHA 1BKCI 4H2EA 1JAPA 4I03A 1RMZA 2XS3A 4PKVA 2JT5A 1K7GA 1B8YA 5D1TA 4IN9A 4Q1LA 2USNA 2DW0A 3LJGA 2EROA 1SU3A 4A7BA 1B3DA 4JA1A 1DMTA 1GE6A 3Q2HA 4G9LA 1BQQM 3ELMA 2W13A 1OM7A 1S4BP 5I3MA 3B8ZA 1KUHA 3AYKA 1SATA 2D1OA 2ERPA 2FV9A 4GWNA 1JH1A 1BSWA 2E2DA 2OY4A 4GF1A 4DPEA 1I73A 4WZVA 2O3EA 1MNCA 3L0VA 1AYKA 2OVZA 4GR0A 3U1RA 3LMCA 4I35A 1ASTA 1JANA 1R1HA 3WV2A 1FLSA 1XAXA 3HBVP 2X3CA 3LGPA 3DTIA 3LQ0A 4WKIA 5BPAA 5D7WA 1HFSA 5I12A 2X7MA 2J0TA 2TCLA 1G4KA 5D1SA 3TVCA 1OS9A 3HDAP 2MLRA 4DD8A 3P1VA 1XFXA 3KHIA 1UMTA 4GWMA 3RTTA 4AXQA 1XFYA 1C7KA 1XM5A 1BUDA 2JIHA 1UMSA 4R3VA 2YUFA 1OO9A 1HY7A 1OM6A 1XFWA 1G9KA 3HY7A 1XURA 1Y0VA 2OY2A 2W15A 1SMPA 3AIGA 5CZMA 2K2GA 4FVLA 1CK7A 1R1JA 3ZVSA 2DW1A 1PWPA 1D8MA 3EDHA 1C8TA 5D1UA 1BQOA 4PKSA 3KWVC 2J83A 1JAQA 3NX7A 1CXVA 1BZSA 4H1QA 3SHIA 1GE5A 1ND1A 1EUBA 3V96B 2MZIA 2POJA 3O64A 2A8HA 1GO7P 3DPEA 1GXDA 4H30A 456CA 1TVIA 4AYKA 2E3XA 3LQBA 1YCMA 3LIRA 2QPJA 1UTTA 1KBCA 4PKQA 3KEKA 1I1IP 1BM6A 2X3BA 4EFSA 1PWWA 2MZEA 3O2XA 1I76A 1QJIA 1GKDA 2DDYA 3WV3A 1EAKA 2OXWA 1AF0A 2OW9A 1KUKA 3EWJA 3L0TA 3EDGA 2N8RA 1MMQA 3F19A 1CAQA 4L7AA 3ZUKA 2AYKA 3LK8A 4WKEA 1D8FA 4H3XA 1IAAA 2WO9A 3OHOA 5I43A 1ATLA 3HDBA 4J4MA 1RM8A 3EDIA 1R54A 4PKTA 1J7NA 1BKCE 1O0QA 5L79A 3VI1A 2DW2A 1KAPP 3BA0A 830CA 3KECA 4HMAA 4H82A 3TS4A 4GUYA 1BUVM 1QIBA 2HU6A 4QKZA 2CLTA 3F18A 5L7FA 1DTHA 1OS2A 2MZHA 1D5JA 2OW1A 4H76A 1FBLA 1EB6A 1XUDA 2XS4A 1ZXCA 4DF9A 1GE7A 3LILA 3F17A 5BOTA 1CGLA 3DPFA 1JIZA 2KRJA 966CA 1JIWP 2PJTA 2DDFA 3LUMA 4XCTA 1AKLA 2V4BA 2JT6A 3EHYA 1ZTQA 5JMYA 4L63A 1WNIA 1QJJA 3UVCA 1USNA 1H71P 2RJPA 1G05A 3RTSA 3B92A 1XFUA 1ZXVA 2Z2DA 1GO8P 2Y6DA 2YB9A 3F1AA 2OW2A 4XM8A 1IACA 4JPAA 2W12A 1IABA 3USNA 1KUGA 1MMBA 3F16A 1SLMA 1C3IA 1PWUA 1OMJA 3AYUA 4IUWA 3KRYA 3WV1A 1CQRA 2K9CA 3K7LA 4XBHA 5B5OA 2YIGA 3LEAA 2WOAA 1HFCA 4GR3A 4JP4A 3LUNA 1Q3AA 4DV8A 3E8RA 1D7XA 3DSLA 1O0TA 3B2ZA 3LIKA 1XFVA 2FV5A 3HBUP 4AUOA 3F15A 2ERQA 2WO8A 1IAEA 3TSKA 5D2BA 3KEJA 1HV5A 2L0RA 3I7IA 5B5PA 4CTHA 4FXYP 3HYGA 1YOUA 3G42A 2OZRA 3I7GA 1PWVA 1OZ9A 3KMCA 3G5CA 4FXQA 2Y6CA 1G49A 1Z3JA 2W14A 1JK3A 1QICA 1BIWA 1OM8A 3GBOA 1HTDA 2SRTA 1JJ9A 5I2ZA 2AIGP 1IAGA 4HX3A 2OVXA 1FM1A 1R55A 1MMPA 4G0DA 5CXAA 1CGFA 4PKRA 3LJZA 2CKIA 1SRPA 1ZP5A 1IADA 4L6TA 3LKAA 4H84A 1JAOA 1QIAA 2I47A 1CGEA 4XM7A 1KUIA 4JQGA 3DL1A 2OXZA 1A86A 2JNPA 5BOYA 1YP1A 3DTKA 1R1IA 4H49A 4XM6A 1GKCA 3ZXHA 3CKIA 4AIGA 4ILWD 4PKUA 4A3WA 2D1NA 2X3AA 3K7NA 2MLSA 4JIJA 3EDZA 1L6JA 1XFZA
chains in the Genus database with same CATH topology
1CIZA 3Q2GA 4IJOA 5I4OA 1JKYA 3MA2A 2W0DA 3VTGA 4WK7A 3DNGA 5LABA 1Y93A 2RJQA 1XUCA 4L19A 3HB2P 3HY9A 1Y8JA 3KMEA 3P24A 3LJTA 1KUFA 5H8XA 1G12A 1ZVXA 3OHLA 1UEAA 3TT4A 2OI0A 5D3CA 3DWBA 1ROSA 3N2UA 1YQYA 5I0LA 4GQLA 2OW0A 3N2VA 4WF6A 1ZS0A 3DTEA 1A85A 2JSDA 1HOVA 4FU4A 1MMRA 1BKCA 3EHXA 3LE9A 1K7QA 4ON1A 1QUAA 2O36A 4ZR5A 1UTZA 4GR8A 1SLNA 1K7IA 1PWQA 2OXUA 4PKWA 5CUHA 1BKCI 4H2EA 1JAPA 4I03A 1RMZA 2XS3A 4PKVA 2JT5A 1K7GA 1B8YA 5D1TA 4IN9A 4Q1LA 2USNA 2DW0A 3LJGA 2EROA 1SU3A 4A7BA 1B3DA 4JA1A 1DMTA 1GE6A 3Q2HA 4G9LA 1BQQM 3ELMA 2W13A 1OM7A 1S4BP 5I3MA 3B8ZA 1KUHA 3AYKA 1SATA 2D1OA 2ERPA 2FV9A 4GWNA 1JH1A 1BSWA 2E2DA 2OY4A 4GF1A 4DPEA 1I73A 4WZVA 2O3EA 1MNCA 3L0VA 1AYKA 2OVZA 4GR0A 3U1RA 3LMCA 4I35A 1ASTA 1JANA 1R1HA 3WV2A 1FLSA 3HBVP 2X3CA 3LGPA 3DTIA 3LQ0A 4WKIA 5BPAA 5D7WA 1HFSA 5I12A 2X7MA 2J0TA 2TCLA 1G4KA 5D1SA 3TVCA 1OS9A 3HDAP 2MLRA 4DD8A 3P1VA 1XFXA 3KHIA 1UMTA 4GWMA 3RTTA 4AXQA 1XFYA 1C7KA 1BUDA 2JIHA 1UMSA 4R3VA 2YUFA 1OO9A 1HY7A 1OM6A 1XFWA 1G9KA 3HY7A 1XURA 1Y0VA 2OY2A 2W15A 1SMPA 3AIGA 5CZMA 2K2GA 4FVLA 1CK7A 1R1JA 3ZVSA 2DW1A 1PWPA 1D8MA 3EDHA 1C8TA 5D1UA 1BQOA 4PKSA 3KWVC 2J83A 1JAQA 3NX7A 1CXVA 1BZSA 4H1QA 3SHIA 1GE5A 1ND1A 1EUBA 3V96B 2MZIA 2POJA 3O64A 2A8HA 1GO7P 3DPEA 1GXDA 4H30A 456CA 4AYKA 2E3XA 3LQBA 1YCMA 3LIRA 2QPJA 1UTTA 1KBCA 4PKQA 3KEKA 1I1IP 1BM6A 2X3BA 4EFSA 1PWWA 2MZEA 3O2XA 1I76A 1QJIA 1GKDA 2DDYA 3WV3A 1EAKA 2OXWA 1AF0A 2OW9A 1KUKA 3EWJA 3L0TA 3EDGA 2N8RA 1MMQA 3F19A 1CAQA 4L7AA 3ZUKA 2AYKA 3LK8A 4WKEA 1D8FA 4H3XA 1IAAA 2WO9A 3OHOA 5I43A 1ATLA 3HDBA 4J4MA 1RM8A 3EDIA 1R54A 4PKTA 1J7NA 1BKCE 1O0QA 5L79A 3VI1A 2DW2A 1KAPP 3BA0A 830CA 3KECA 4HMAA 4H82A 3TS4A 4GUYA 1BUVM 1QIBA 2HU6A 4QKZA 2CLTA 3F18A 5L7FA 1DTHA 1OS2A 2MZHA 1D5JA 2OW1A 4H76A 1FBLA 1EB6A 1XUDA 2XS4A 1ZXCA 4DF9A 1GE7A 3LILA 3F17A 5BOTA 1CGLA 3DPFA 1JIZA 2KRJA 966CA 1JIWP 2PJTA 2DDFA 3LUMA 4XCTA 1AKLA 2V4BA 2JT6A 3EHYA 1ZTQA 5JMYA 4L63A 1WNIA 1QJJA 3UVCA 1USNA 1H71P 2RJPA 1G05A 3RTSA 3B92A 1XFUA 1ZXVA 2Z2DA 1GO8P 2Y6DA 2YB9A 3F1AA 2OW2A 4XM8A 1IACA 4JPAA 2W12A 1IABA 3USNA 1KUGA 1MMBA 3F16A 1SLMA 1C3IA 1PWUA 1OMJA 3AYUA 4IUWA 3KRYA 3WV1A 1CQRA 2K9CA 3K7LA 4XBHA 5B5OA 2YIGA 3LEAA 2WOAA 1HFCA 4GR3A 4JP4A 3LUNA 1Q3AA 4DV8A 3E8RA 1D7XA 3DSLA 1O0TA 3B2ZA 3LIKA 1XFVA 2FV5A 3HBUP 4AUOA 3F15A 2ERQA 2WO8A 1IAEA 3TSKA 5D2BA 3KEJA 1HV5A 2L0RA 3I7IA 5B5PA 4CTHA 4FXYP 3HYGA 1YOUA 3G42A 2OZRA 3I7GA 1PWVA 3KMCA 3G5CA 4FXQA 2Y6CA 1G49A 1Z3JA 2W14A 1JK3A 1QICA 1BIWA 1OM8A 3GBOA 1HTDA 2SRTA 1JJ9A 5I2ZA 2AIGP 1IAGA 4HX3A 2OVXA 1FM1A 1R55A 1MMPA 4G0DA 5CXAA 1CGFA 4PKRA 3LJZA 2CKIA 1SRPA 1ZP5A 1IADA 4L6TA 3LKAA 4H84A 1JAOA 1QIAA 2I47A 1CGEA 4XM7A 1KUIA 4JQGA 3DL1A 2OXZA 1A86A 2JNPA 5BOYA 1YP1A 3DTKA 1R1IA 4H49A 4XM6A 1GKCA 3ZXHA 3CKIA 4AIGA 4ILWD 4PKUA 4A3WA 2D1NA 2X3AA 3K7NA 2MLSA 4JIJA 3EDZA 1L6JA 1XFZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CIZ A;  3Q2G A;  4IJO A;  5I4O A;  1JKY A;  3MA2 A;  2W0D A;  3VTG A;  4WK7 A;  3DNG A;  5LAB A;  1Y93 A;  2RJQ A;  1XUC A;  4L19 A;  3HB2 P;  3HY9 A;  1Y8J A;  3KME A;  3P24 A;  3LJT A;  1KUF A;  5H8X A;  1G12 A;  1ZVX A;  3OHL A;  1UEA A;  3TT4 A;  2OI0 A;  5D3C A;  3DWB A;  1ROS A;  3N2U A;  1YQY A;  5I0L A;  4GQL A;  2OW0 A;  3N2V A;  4WF6 A;  1ZS0 A;  1HOV A;  1A85 A;  2JSD A;  4FU4 A;  1MMR A;  1BKC A;  3EHX A;  3LE9 A;  1K7Q A;  4ON1 A;  1QUA A;  2O36 A;  4ZR5 A;  1UTZ A;  4GR8 A;  1SLN A;  1K7I A;  1PWQ A;  2OXU A;  4PKW A;  5CUH A;  1BKC I;  4H2E A;  1JAP A;  4I03 A;  1RMZ A;  2XS3 A;  4PKV A;  2JT5 A;  1K7G A;  1B8Y A;  5D1T A;  4IN9 A;  4Q1L A;  2USN A;  2DW0 A;  3LJG A;  2ERO A;  1SU3 A;  4A7B A;  1B3D A;  4JA1 A;  1DMT A;  1GE6 A;  3Q2H A;  4G9L A;  1BQQ M;  3ELM A;  2W13 A;  1OM7 A;  1S4B P;  5I3M A;  3B8Z A;  1KUH A;  3AYK A;  1SAT A;  2D1O A;  2ERP A;  2FV9 A;  4GWN A;  1JH1 A;  1BSW A;  2E2D A;  2OY4 A;  4GF1 A;  4DPE A;  1I73 A;  4WZV A;  2O3E A;  1MNC A;  3L0V A;  1AYK A;  2OVZ A;  4GR0 A;  3U1R A;  3LMC A;  4I35 A;  1AST A;  1JAN A;  1R1H A;  3WV2 A;  1FLS A;  3HBV P;  2X3C A;  3LGP A;  3LQ0 A;  4WKI A;  5BPA A;  5D7W A;  1HFS A;  5I12 A;  2X7M A;  2J0T A;  2TCL A;  1G4K A;  5D1S A;  3TVC A;  1OS9 A;  3HDA P;  2MLR A;  4DD8 A;  3P1V A;  1XFX A;  3KHI A;  1UMT A;  4GWM A;  3RTT A;  4AXQ A;  1XFY A;  1C7K A;  1BUD A;  2JIH A;  1UMS A;  4R3V A;  1OO9 A;  1HY7 A;  1OM6 A;  1XFW A;  1G9K A;  3HY7 A;  1XUR A;  1Y0V A;  2OY2 A;  2W15 A;  1SMP A;  3AIG A;  5CZM A;  2K2G A;  4FVL A;  1CK7 A;  1R1J A;  3ZVS A;  2DW1 A;  1PWP A;  1D8M A;  3EDH A;  1C8T A;  5D1U A;  1BQO A;  4PKS A;  3KWV C;  2J83 A;  1JAQ A;  3NX7 A;  1CXV A;  1BZS A;  4H1Q A;  3SHI A;  1GE5 A;  1ND1 A;  1EUB A;  3V96 B;  2MZI A;  2POJ A;  3O64 A;  2A8H A;  1GO7 P;  3DPE A;  1GXD A;  4H30 A;  456C A;  4AYK A;  2E3X A;  3LQB A;  1YCM A;  3LIR A;  2QPJ A;  1UTT A;  1KBC A;  4PKQ A;  3KEK A;  1I1I P;  1BM6 A;  2X3B A;  4EFS A;  1PWW A;  2MZE A;  3O2X A;  1I76 A;  1QJI A;  1GKD A;  2DDY A;  3WV3 A;  1EAK A;  2OXW A;  1AF0 A;  2OW9 A;  1KUK A;  3EWJ A;  3L0T A;  3EDG A;  2N8R A;  1MMQ A;  3F19 A;  1CAQ A;  3ZUK A;  2AYK A;  3LK8 A;  4WKE A;  1D8F A;  4H3X A;  1IAA A;  2WO9 A;  3OHO A;  5I43 A;  1ATL A;  3HDB A;  4J4M A;  1RM8 A;  3EDI A;  1R54 A;  4PKT A;  1J7N A;  1BKC E;  1O0Q A;  5L79 A;  3VI1 A;  2DW2 A;  1KAP P;  3BA0 A;  830C A;  3KEC A;  4HMA A;  4H82 A;  3TS4 A;  4GUY A;  1BUV M;  1QIB A;  2HU6 A;  4QKZ A;  2CLT A;  3F18 A;  5L7F A;  1DTH A;  1OS2 A;  2MZH A;  1D5J A;  2OW1 A;  4H76 A;  1FBL A;  1EB6 A;  1XUD A;  2XS4 A;  1ZXC A;  4DF9 A;  1GE7 A;  3LIL A;  3F17 A;  5BOT A;  1CGL A;  3DPF A;  1JIZ A;  2KRJ A;  966C A;  1JIW P;  2PJT A;  2DDF A;  3LUM A;  4XCT A;  1AKL A;  2V4B A;  2JT6 A;  3EHY A;  1ZTQ A;  5JMY A;  4L63 A;  1WNI A;  1QJJ A;  3UVC A;  1USN A;  1H71 P;  2RJP A;  1G05 A;  3RTS A;  3B92 A;  1XFU A;  1ZXV A;  2Z2D A;  1GO8 P;  2Y6D A;  2YB9 A;  3F1A A;  2OW2 A;  4XM8 A;  1IAC A;  4JPA A;  2W12 A;  1IAB A;  3USN A;  1KUG A;  1MMB A;  3F16 A;  1SLM A;  1C3I A;  1PWU A;  1OMJ A;  3AYU A;  4IUW A;  3KRY A;  3WV1 A;  1CQR A;  2K9C A;  3K7L A;  4XBH A;  5B5O A;  2YIG A;  3LEA A;  2WOA A;  1HFC A;  4GR3 A;  4JP4 A;  3LUN A;  1Q3A A;  4DV8 A;  3E8R A;  1D7X A;  3DSL A;  1O0T A;  3B2Z A;  3LIK A;  1XFV A;  2FV5 A;  3HBU P;  4AUO A;  3F15 A;  2ERQ A;  2WO8 A;  1IAE A;  3TSK A;  5D2B A;  3KEJ A;  1HV5 A;  2L0R A;  3I7I A;  5B5P A;  4CTH A;  4FXY P;  3HYG A;  1YOU A;  3G42 A;  2OZR A;  3I7G A;  1PWV A;  3KMC A;  3G5C A;  4FXQ A;  2Y6C A;  1G49 A;  1Z3J A;  2W14 A;  1JK3 A;  1QIC A;  1BIW A;  1OM8 A;  3GBO A;  1HTD A;  2SRT A;  1JJ9 A;  5I2Z A;  2AIG P;  1IAG A;  4HX3 A;  2OVX A;  1FM1 A;  1R55 A;  1MMP A;  4G0D A;  5CXA A;  1CGF A;  4PKR A;  3LJZ A;  2CKI A;  1SRP A;  1ZP5 A;  1IAD A;  4L6T A;  3LKA A;  4H84 A;  1JAO A;  1QIA A;  2I47 A;  1CGE A;  4XM7 A;  1KUI A;  4JQG A;  3DL1 A;  2OXZ A;  1A86 A;  2JNP A;  5BOY A;  1YP1 A;  1R1I A;  4H49 A;  4XM6 A;  1GKC A;  3ZXH A;  3CKI A;  4AIG A;  4ILW D;  4PKU A;  4A3W A;  2D1N A;  2X3A A;  3K7N A;  2MLS A;  4JIJ A;  3EDZ A;  1L6J A;  1XFZ A; 
#chains in the Genus database with same CATH topology
 1CIZ A;  3Q2G A;  4IJO A;  5I4O A;  1JKY A;  3MA2 A;  2W0D A;  3VTG A;  4WK7 A;  3DNG A;  5LAB A;  1Y93 A;  2RJQ A;  1XUC A;  4L19 A;  3HB2 P;  3HY9 A;  1Y8J A;  3KME A;  3P24 A;  3LJT A;  1KUF A;  5H8X A;  1G12 A;  1ZVX A;  3OHL A;  1UEA A;  3TT4 A;  2OI0 A;  5D3C A;  3DWB A;  1ROS A;  3N2U A;  1YQY A;  5I0L A;  4GQL A;  2OW0 A;  3N2V A;  4WF6 A;  1ZS0 A;  3DTE A;  1A85 A;  2JSD A;  1HOV A;  4FU4 A;  1MMR A;  1BKC A;  3EHX A;  3LE9 A;  1K7Q A;  4ON1 A;  1QUA A;  2O36 A;  4ZR5 A;  1UTZ A;  4GR8 A;  1SLN A;  1K7I A;  1PWQ A;  2OXU A;  4PKW A;  5CUH A;  1BKC I;  4H2E A;  1JAP A;  4I03 A;  1RMZ A;  2XS3 A;  4PKV A;  2JT5 A;  1K7G A;  1B8Y A;  5D1T A;  4IN9 A;  4Q1L A;  2USN A;  2DW0 A;  3LJG A;  2ERO A;  1SU3 A;  4A7B A;  1B3D A;  4JA1 A;  1DMT A;  1GE6 A;  3Q2H A;  4G9L A;  1BQQ M;  3ELM A;  2W13 A;  1OM7 A;  1S4B P;  5I3M A;  3B8Z A;  1KUH A;  3AYK A;  1SAT A;  2D1O A;  2ERP A;  2FV9 A;  4GWN A;  1JH1 A;  1BSW A;  2E2D A;  2OY4 A;  4GF1 A;  4DPE A;  1I73 A;  4WZV A;  2O3E A;  1MNC A;  3L0V A;  1AYK A;  2OVZ A;  4GR0 A;  3U1R A;  3LMC A;  4I35 A;  1AST A;  1JAN A;  1R1H A;  3WV2 A;  1FLS A;  1XAX A;  3HBV P;  2X3C A;  3LGP A;  3DTI A;  3LQ0 A;  4WKI A;  5BPA A;  5D7W A;  1HFS A;  5I12 A;  2X7M A;  2J0T A;  2TCL A;  1G4K A;  5D1S A;  3TVC A;  1OS9 A;  3HDA P;  2MLR A;  4DD8 A;  3P1V A;  1XFX A;  3KHI A;  1UMT A;  4GWM A;  3RTT A;  4AXQ A;  1XFY A;  1C7K A;  1XM5 A;  1BUD A;  2JIH A;  1UMS A;  4R3V A;  2YUF A;  1OO9 A;  1HY7 A;  1OM6 A;  1XFW A;  1G9K A;  3HY7 A;  1XUR A;  1Y0V A;  2OY2 A;  2W15 A;  1SMP A;  3AIG A;  5CZM A;  2K2G A;  4FVL A;  1CK7 A;  1R1J A;  3ZVS A;  2DW1 A;  1PWP A;  1D8M A;  3EDH A;  1C8T A;  5D1U A;  1BQO A;  4PKS A;  3KWV C;  2J83 A;  1JAQ A;  3NX7 A;  1CXV A;  1BZS A;  4H1Q A;  3SHI A;  1GE5 A;  1ND1 A;  1EUB A;  3V96 B;  2MZI A;  2POJ A;  3O64 A;  2A8H A;  1GO7 P;  3DPE A;  1GXD A;  4H30 A;  456C A;  1TVI A;  4AYK A;  2E3X A;  3LQB A;  1YCM A;  3LIR A;  2QPJ A;  1UTT A;  1KBC A;  4PKQ A;  3KEK A;  1I1I P;  1BM6 A;  2X3B A;  4EFS A;  1PWW A;  2MZE A;  3O2X A;  1I76 A;  1QJI A;  1GKD A;  2DDY A;  3WV3 A;  1EAK A;  2OXW A;  1AF0 A;  2OW9 A;  1KUK A;  3EWJ A;  3L0T A;  3EDG A;  2N8R A;  1MMQ A;  3F19 A;  1CAQ A;  4L7A A;  3ZUK A;  2AYK A;  3LK8 A;  4WKE A;  1D8F A;  4H3X A;  1IAA A;  2WO9 A;  3OHO A;  5I43 A;  1ATL A;  3HDB A;  4J4M A;  1RM8 A;  3EDI A;  1R54 A;  4PKT A;  1J7N A;  1BKC E;  1O0Q A;  5L79 A;  3VI1 A;  2DW2 A;  1KAP P;  3BA0 A;  830C A;  3KEC A;  4HMA A;  4H82 A;  3TS4 A;  4GUY A;  1BUV M;  1QIB A;  2HU6 A;  4QKZ A;  2CLT A;  3F18 A;  5L7F A;  1DTH A;  1OS2 A;  2MZH A;  1D5J A;  2OW1 A;  4H76 A;  1FBL A;  1EB6 A;  1XUD A;  2XS4 A;  1ZXC A;  4DF9 A;  1GE7 A;  3LIL A;  3F17 A;  5BOT A;  1CGL A;  3DPF A;  1JIZ A;  2KRJ A;  966C A;  1JIW P;  2PJT A;  2DDF A;  3LUM A;  4XCT A;  1AKL A;  2V4B A;  2JT6 A;  3EHY A;  1ZTQ A;  5JMY A;  4L63 A;  1WNI A;  1QJJ A;  3UVC A;  1USN A;  1H71 P;  2RJP A;  1G05 A;  3RTS A;  3B92 A;  1XFU A;  1ZXV A;  2Z2D A;  1GO8 P;  2Y6D A;  2YB9 A;  3F1A A;  2OW2 A;  4XM8 A;  1IAC A;  4JPA A;  2W12 A;  1IAB A;  3USN A;  1KUG A;  1MMB A;  3F16 A;  1SLM A;  1C3I A;  1PWU A;  1OMJ A;  3AYU A;  4IUW A;  3KRY A;  3WV1 A;  1CQR A;  2K9C A;  3K7L A;  4XBH A;  5B5O A;  2YIG A;  3LEA A;  2WOA A;  1HFC A;  4GR3 A;  4JP4 A;  3LUN A;  1Q3A A;  4DV8 A;  3E8R A;  1D7X A;  3DSL A;  1O0T A;  3B2Z A;  3LIK A;  1XFV A;  2FV5 A;  3HBU P;  4AUO A;  3F15 A;  2ERQ A;  2WO8 A;  1IAE A;  3TSK A;  5D2B A;  3KEJ A;  1HV5 A;  2L0R A;  3I7I A;  5B5P A;  4CTH A;  4FXY P;  3HYG A;  1YOU A;  3G42 A;  2OZR A;  3I7G A;  1PWV A;  1OZ9 A;  3KMC A;  3G5C A;  4FXQ A;  2Y6C A;  1G49 A;  1Z3J A;  2W14 A;  1JK3 A;  1QIC A;  1BIW A;  1OM8 A;  3GBO A;  1HTD A;  2SRT A;  1JJ9 A;  5I2Z A;  2AIG P;  1IAG A;  4HX3 A;  2OVX A;  1FM1 A;  1R55 A;  1MMP A;  4G0D A;  5CXA A;  1CGF A;  4PKR A;  3LJZ A;  2CKI A;  1SRP A;  1ZP5 A;  1IAD A;  4L6T A;  3LKA A;  4H84 A;  1JAO A;  1QIA A;  2I47 A;  1CGE A;  4XM7 A;  1KUI A;  4JQG A;  3DL1 A;  2OXZ A;  1A86 A;  2JNP A;  5BOY A;  1YP1 A;  3DTK A;  1R1I A;  4H49 A;  4XM6 A;  1GKC A;  3ZXH A;  3CKI A;  4AIG A;  4ILW D;  4PKU A;  4A3W A;  2D1N A;  2X3A A;  3K7N A;  2MLS A;  4JIJ A;  3EDZ A;  1L6J A;  1XFZ A; 
#chains in the Genus database with same CATH homology
 1CIZ A;  3Q2G A;  4IJO A;  5I4O A;  1JKY A;  3MA2 A;  2W0D A;  3VTG A;  4WK7 A;  3DNG A;  5LAB A;  1Y93 A;  2RJQ A;  1XUC A;  4L19 A;  3HB2 P;  3HY9 A;  1Y8J A;  3KME A;  3P24 A;  3LJT A;  1KUF A;  5H8X A;  1G12 A;  1ZVX A;  3OHL A;  1UEA A;  3TT4 A;  2OI0 A;  5D3C A;  3DWB A;  1ROS A;  3N2U A;  1YQY A;  5I0L A;  4GQL A;  2OW0 A;  3N2V A;  4WF6 A;  1ZS0 A;  3DTE A;  1A85 A;  2JSD A;  1HOV A;  4FU4 A;  1MMR A;  1BKC A;  3EHX A;  3LE9 A;  1K7Q A;  4ON1 A;  1QUA A;  2O36 A;  4ZR5 A;  1UTZ A;  4GR8 A;  1SLN A;  1K7I A;  1PWQ A;  2OXU A;  4PKW A;  5CUH A;  1BKC I;  4H2E A;  1JAP A;  4I03 A;  1RMZ A;  2XS3 A;  4PKV A;  2JT5 A;  1K7G A;  1B8Y A;  5D1T A;  4IN9 A;  4Q1L A;  2USN A;  2DW0 A;  3LJG A;  2ERO A;  1SU3 A;  4A7B A;  1B3D A;  4JA1 A;  1DMT A;  1GE6 A;  3Q2H A;  4G9L A;  1BQQ M;  3ELM A;  2W13 A;  1OM7 A;  1S4B P;  5I3M A;  3B8Z A;  1KUH A;  3AYK A;  1SAT A;  2D1O A;  2ERP A;  2FV9 A;  4GWN A;  1JH1 A;  1BSW A;  2E2D A;  2OY4 A;  4GF1 A;  4DPE A;  1I73 A;  4WZV A;  2O3E A;  1MNC A;  3L0V A;  1AYK A;  2OVZ A;  4GR0 A;  3U1R A;  3LMC A;  4I35 A;  1AST A;  1JAN A;  1R1H A;  3WV2 A;  1FLS A;  3HBV P;  2X3C A;  3LGP A;  3DTI A;  3LQ0 A;  4WKI A;  5BPA A;  5D7W A;  1HFS A;  5I12 A;  2X7M A;  2J0T A;  2TCL A;  1G4K A;  5D1S A;  3TVC A;  1OS9 A;  3HDA P;  2MLR A;  4DD8 A;  3P1V A;  1XFX A;  3KHI A;  1UMT A;  4GWM A;  3RTT A;  4AXQ A;  1XFY A;  1C7K A;  1BUD A;  2JIH A;  1UMS A;  4R3V A;  2YUF A;  1OO9 A;  1HY7 A;  1OM6 A;  1XFW A;  1G9K A;  3HY7 A;  1XUR A;  1Y0V A;  2OY2 A;  2W15 A;  1SMP A;  3AIG A;  5CZM A;  2K2G A;  4FVL A;  1CK7 A;  1R1J A;  3ZVS A;  2DW1 A;  1PWP A;  1D8M A;  3EDH A;  1C8T A;  5D1U A;  1BQO A;  4PKS A;  3KWV C;  2J83 A;  1JAQ A;  3NX7 A;  1CXV A;  1BZS A;  4H1Q A;  3SHI A;  1GE5 A;  1ND1 A;  1EUB A;  3V96 B;  2MZI A;  2POJ A;  3O64 A;  2A8H A;  1GO7 P;  3DPE A;  1GXD A;  4H30 A;  456C A;  4AYK A;  2E3X A;  3LQB A;  1YCM A;  3LIR A;  2QPJ A;  1UTT A;  1KBC A;  4PKQ A;  3KEK A;  1I1I P;  1BM6 A;  2X3B A;  4EFS A;  1PWW A;  2MZE A;  3O2X A;  1I76 A;  1QJI A;  1GKD A;  2DDY A;  3WV3 A;  1EAK A;  2OXW A;  1AF0 A;  2OW9 A;  1KUK A;  3EWJ A;  3L0T A;  3EDG A;  2N8R A;  1MMQ A;  3F19 A;  1CAQ A;  4L7A A;  3ZUK A;  2AYK A;  3LK8 A;  4WKE A;  1D8F A;  4H3X A;  1IAA A;  2WO9 A;  3OHO A;  5I43 A;  1ATL A;  3HDB A;  4J4M A;  1RM8 A;  3EDI A;  1R54 A;  4PKT A;  1J7N A;  1BKC E;  1O0Q A;  5L79 A;  3VI1 A;  2DW2 A;  1KAP P;  3BA0 A;  830C A;  3KEC A;  4HMA A;  4H82 A;  3TS4 A;  4GUY A;  1BUV M;  1QIB A;  2HU6 A;  4QKZ A;  2CLT A;  3F18 A;  5L7F A;  1DTH A;  1OS2 A;  2MZH A;  1D5J A;  2OW1 A;  4H76 A;  1FBL A;  1EB6 A;  1XUD A;  2XS4 A;  1ZXC A;  4DF9 A;  1GE7 A;  3LIL A;  3F17 A;  5BOT A;  1CGL A;  3DPF A;  1JIZ A;  2KRJ A;  966C A;  1JIW P;  2PJT A;  2DDF A;  3LUM A;  4XCT A;  1AKL A;  2V4B A;  2JT6 A;  3EHY A;  1ZTQ A;  5JMY A;  4L63 A;  1WNI A;  1QJJ A;  3UVC A;  1USN A;  1H71 P;  2RJP A;  1G05 A;  3RTS A;  3B92 A;  1XFU A;  1ZXV A;  2Z2D A;  1GO8 P;  2Y6D A;  2YB9 A;  3F1A A;  2OW2 A;  4XM8 A;  1IAC A;  4JPA A;  2W12 A;  1IAB A;  3USN A;  1KUG A;  1MMB A;  3F16 A;  1SLM A;  1C3I A;  1PWU A;  1OMJ A;  3AYU A;  4IUW A;  3KRY A;  3WV1 A;  1CQR A;  2K9C A;  3K7L A;  4XBH A;  5B5O A;  2YIG A;  3LEA A;  2WOA A;  1HFC A;  4GR3 A;  4JP4 A;  3LUN A;  1Q3A A;  4DV8 A;  3E8R A;  1D7X A;  3DSL A;  1O0T A;  3B2Z A;  3LIK A;  1XFV A;  2FV5 A;  3HBU P;  4AUO A;  3F15 A;  2ERQ A;  2WO8 A;  1IAE A;  3TSK A;  5D2B A;  3KEJ A;  1HV5 A;  2L0R A;  3I7I A;  5B5P A;  4CTH A;  4FXY P;  3HYG A;  1YOU A;  3G42 A;  2OZR A;  3I7G A;  1PWV A;  3KMC A;  3G5C A;  4FXQ A;  2Y6C A;  1G49 A;  1Z3J A;  2W14 A;  1JK3 A;  1QIC A;  1BIW A;  1OM8 A;  3GBO A;  1HTD A;  2SRT A;  1JJ9 A;  5I2Z A;  2AIG P;  1IAG A;  4HX3 A;  2OVX A;  1FM1 A;  1R55 A;  1MMP A;  4G0D A;  5CXA A;  1CGF A;  4PKR A;  3LJZ A;  2CKI A;  1SRP A;  1ZP5 A;  1IAD A;  4L6T A;  3LKA A;  4H84 A;  1JAO A;  1QIA A;  2I47 A;  1CGE A;  4XM7 A;  1KUI A;  4JQG A;  3DL1 A;  2OXZ A;  1A86 A;  2JNP A;  5BOY A;  1YP1 A;  3DTK A;  1R1I A;  4H49 A;  4XM6 A;  1GKC A;  3ZXH A;  3CKI A;  4AIG A;  4ILW D;  4PKU A;  4A3W A;  2D1N A;  2X3A A;  3K7N A;  2MLS A;  4JIJ A;  3EDZ A;  1L6J A;  1XFZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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