3HY9A

Crystal structure of the catalytic domain of adamts-5 in complex with an amino-2-indanol compound
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
217
structure length
217
Chain Sequence
b'SRARQVELLLVADASMARKYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQI'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Catalytic Domain of ADAMTS-5
publication title Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 74
structure length 217
sequence length 217
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01421 Reprolysin Reprolysin (M12B) family zinc metalloprotease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3hy9A00
3KRYA 5D1UA 2J83A 2KRJA 3EHYA 1OMJA 2V4BA 3K7NA 3ZUKA 2X7MA 1D8MA 4AXQA 3F1AA 1AKLA 4A7BA 1HY7A 3MA2A 1CXVA 3EHXA 2OXZA 1CGLA 3P1VA 4PKQA 1SU3A 5L79A 1DMTA 4L6TA 1ZS0A 1UTTA 2HU6A 3LGPA 1JANA 4WZVA 2CKIA 5BOYA 1OO9A 1BQQM 3I7GA 2L0RA 1CGFA 1SRPA 1QIBA 1FLSA 1USNA 4GR8A 5CXAA 1J7NA 5D3CA 1B8YA 3LK8A 2JT5A 4JP4A 1EUBA 1GO7P 830CA 4JQGA 4AUOA 1JIZA 3WV3A 1OS9A 1GE6A 1UTZA 1UMTA 5H8XA 2O36A 3G42A 3AYKA 1IAEA 4IUWA 2OW1A 3LJZA 4FXQA 1OM6A 3F15A 3G5CA 3B92A 4DF9A 3LJTA 2OY4A 2Z2DA 3EWJA 1D8FA 456CA 1OM7A 2YIGA 3UVCA 2Y6DA 1QIAA 4GWNA 1ZXVA 3LQ0A 4DPEA 2RJQA 4GWMA 3BA0A 1BQOA 4FXYP 3I7IA 2WOAA 2MLRA 1IAAA 2W13A 1HFCA 3USNA 3ZVSA 1JH1A 4R3VA 1RM8A 5I0LA 1GO8P 3P24A 1KAPP 2W14A 1MNCA 1GKDA 1O0QA 4DV8A 1QJJA 3DWBA 2E2DA 2WO8A 4DD8A 3OHOA 1FM1A 1CK7A 2X3BA 4A3WA 1IABA 4FVLA 1ATLA 3LKAA 1CQRA 1XFUA 5D2BA 1I73A 3AIGA 2J0TA 4PKTA 5JMYA 1I1IP 2OXUA 3HB2P 3LIKA 1JJ9A 2WO9A 1UEAA 1GKCA 1R1IA 1Y93A 2D1OA 4G0DA 3EDHA 1AYKA 2N8RA 2DDFA 2ERPA 1QJIA 3HBVP 1GE5A 1PWQA 4WK7A 2EROA 2XS3A 3O64A 2X3CA 3KMCA 4H49A 3DL1A 1BKCA 1JKYA 2DW2A 1KUKA 1UMSA 1YOUA 1O0TA 3LUMA 1K7IA 3F18A 3N2VA 2I47A 1IADA 1C3IA 4XM8A 3KEKA 4GUYA 3N2UA 1D5JA 4L19A 2FV9A 1SLMA 3TSKA 1MMQA 4Q1LA 2OZRA 4I03A 4ON1A 3B8ZA 4H82A 5D1TA 2D1NA 3OHLA 1GXDA 2K2GA 1R55A 2JIHA 3F16A 4L63A 3DNGA 4HX3A 3VI1A 3L0TA 1BSWA 1HV5A 3U1RA 4H76A 1PWPA 2DDYA 3O2XA 2RJPA 1BUDA 1ASTA 4PKVA 1ZXCA 3AYUA 966CA 2JSDA 1BZSA 2OVXA 1C7KA 1JAOA 1BUVM 1B3DA 4XBHA 3HDAP 4PKRA 1GE7A 1ND1A 1FBLA 3Q2GA 1ZTQA 3SHIA 2QPJA 2OXWA 1HOVA 1ROSA 3EDZA 1JAPA 2K9CA 2OW0A 1IAGA 1YCMA 2FV5A 4WF6A 5CZMA 3HY7A 1AF0A 3TT4A 3KHIA 2MZIA 5BOTA 1IACA 4CTHA 1KUHA 2OVZA 1ZVXA 3KMEA 3LEAA 4H2EA 1C8TA 1CIZA 1QICA 3HDBA 3K7LA 3DPEA 5I2ZA 4I35A 1BKCE 4QKZA 2OW2A 1JAQA 2E3XA 3L0VA 5I43A 1QUAA 1HFSA 2JNPA 1YP1A 1KUIA 1D7XA 4JA1A 4PKWA 1S4BP 1G4KA 4PKSA 1BKCI 4H84A 4H3XA 4GQLA 4XM6A 2W0DA 1OM8A 1G05A 3ELMA 4WKEA 2TCLA 5D7WA 1CGEA 4WKIA 1KUFA 1MMRA 1XFWA 1G12A 2DW0A 3DSLA 1CAQA 1SATA 1KBCA 4H1QA 3CKIA 5L7FA 2OW9A 4IN9A 1Y8JA 1G49A 2OI0A 3LE9A 2X3AA 1L6JA 3KWVC 3LILA 2POJA 2MZHA 5I3MA 1JK3A 1PWVA 3LJGA 3F17A 3WV2A 4PKUA 3TVCA 1HTDA 4EFSA 1DTHA 4GR3A 4JIJA 3NX7A 3EDGA 2OY2A 1XFXA 2YB9A 1Q3AA 4ZR5A 1KUGA 1R1JA 2DW1A 2AIGP 5D1SA 3WV1A 2MLSA 3HY9A 3GBOA 1SMPA 4ILWD 1A86A 2XS4A 4GR0A 3DPFA 3TS4A 3E8RA 1PWWA 3B2ZA 2W15A 1XFZA 4AYKA 1R54A 1YQYA 2MZEA 1MMPA 2SRTA 2PJTA 5LABA 1XFYA 1JIWP 4GF1A 1OS2A 3HYGA 5B5OA 3ZXHA 3LQBA 2JT6A 5I4OA 5CUHA 1WNIA 3RTSA 1Y0VA 4XCTA 1XUDA 2Y6CA 1ZP5A 3LIRA 1XUCA 1G9KA 1XURA 3RTTA 1SLNA 1K7GA 4G9LA 2W12A 2O3EA 3VTGA 3V96B 4AIGA 1A85A 4H30A 4IJOA 1R1HA 1XFVA 1BIWA 1K7QA 1MMBA 2CLTA 1PWUA 1Z3JA 2AYKA 1EAKA 3EDIA 2ERQA 4FU4A 4XM7A 1RMZA 3KECA 1I76A 3Q2HA 4J4MA 3HBUP 2A8HA 1H71P 3F19A 3LUNA 5B5PA 5I12A 3KEJA 1BM6A 3LMCA 1EB6A 4JPAA 4HMAA 5BPAA 2USNA
chains in the Genus database with same CATH superfamily
3KRYA 5D1UA 2J83A 2KRJA 3EHYA 1OMJA 2V4BA 3K7NA 3ZUKA 2X7MA 1D8MA 4AXQA 3F1AA 1AKLA 4A7BA 1HY7A 3MA2A 1CXVA 3EHXA 2OXZA 1CGLA 3P1VA 4PKQA 1SU3A 5L79A 1DMTA 4L6TA 1ZS0A 1UTTA 2HU6A 3LGPA 1JANA 4WZVA 2CKIA 5BOYA 1OO9A 1BQQM 3I7GA 2L0RA 1CGFA 1SRPA 1QIBA 1FLSA 1USNA 4GR8A 5CXAA 1J7NA 5D3CA 1B8YA 3LK8A 1TVIA 2JT5A 4JP4A 1EUBA 1GO7P 830CA 4JQGA 4AUOA 1JIZA 3WV3A 1OS9A 1GE6A 1UTZA 1UMTA 5H8XA 2O36A 3G42A 3AYKA 1IAEA 4IUWA 2OW1A 3LJZA 4FXQA 1OM6A 3F15A 3G5CA 3B92A 4DF9A 3LJTA 2OY4A 2Z2DA 3EWJA 1D8FA 456CA 1OM7A 2YIGA 3UVCA 2Y6DA 1QIAA 4GWNA 1ZXVA 3LQ0A 4DPEA 2RJQA 4GWMA 3BA0A 1BQOA 4FXYP 3I7IA 2WOAA 2MLRA 1IAAA 2W13A 1HFCA 3USNA 3ZVSA 1JH1A 4R3VA 1RM8A 5I0LA 1GO8P 3P24A 1KAPP 2W14A 1MNCA 1GKDA 1O0QA 4DV8A 1QJJA 3DWBA 2E2DA 2WO8A 4DD8A 3OHOA 1FM1A 1CK7A 2X3BA 4A3WA 1IABA 4FVLA 1ATLA 3LKAA 2YUFA 1CQRA 1XFUA 5D2BA 1I73A 3AIGA 2J0TA 4L7AA 4PKTA 5JMYA 1I1IP 2OXUA 3HB2P 3LIKA 1JJ9A 2WO9A 1UEAA 1GKCA 1R1IA 1Y93A 2D1OA 4G0DA 3EDHA 1AYKA 2N8RA 2DDFA 2ERPA 1QJIA 3HBVP 1GE5A 1PWQA 4WK7A 2EROA 2XS3A 3O64A 2X3CA 3KMCA 4H49A 3DL1A 1BKCA 1JKYA 2DW2A 1KUKA 1UMSA 1YOUA 1O0TA 3LUMA 1K7IA 3F18A 3N2VA 2I47A 1IADA 1C3IA 4XM8A 3KEKA 4GUYA 3N2UA 1D5JA 4L19A 2FV9A 1SLMA 3TSKA 1MMQA 4Q1LA 2OZRA 4I03A 4ON1A 3B8ZA 4H82A 5D1TA 2D1NA 3OHLA 1GXDA 2K2GA 1R55A 2JIHA 3F16A 4L63A 3DNGA 4HX3A 3VI1A 3L0TA 1BSWA 1HV5A 3U1RA 4H76A 1PWPA 2DDYA 3O2XA 2RJPA 1BUDA 1ASTA 4PKVA 1ZXCA 3AYUA 966CA 2JSDA 1BZSA 2OVXA 1C7KA 1JAOA 1BUVM 1B3DA 4XBHA 3HDAP 4PKRA 1GE7A 1ND1A 1FBLA 3Q2GA 1ZTQA 3SHIA 2QPJA 2OXWA 1HOVA 1ROSA 3EDZA 1JAPA 2K9CA 2OW0A 1IAGA 1YCMA 2FV5A 4WF6A 5CZMA 3HY7A 1AF0A 3TT4A 3KHIA 2MZIA 5BOTA 1IACA 4CTHA 1KUHA 2OVZA 1ZVXA 3KMEA 3LEAA 4H2EA 1C8TA 1CIZA 1QICA 3HDBA 3K7LA 3DPEA 5I2ZA 4I35A 1BKCE 4QKZA 2OW2A 1JAQA 2E3XA 3L0VA 5I43A 1QUAA 1HFSA 1OZ9A 2JNPA 1YP1A 1KUIA 1D7XA 4JA1A 4PKWA 1S4BP 1G4KA 4PKSA 1BKCI 4H84A 4H3XA 4GQLA 4XM6A 2W0DA 1OM8A 1G05A 3ELMA 4WKEA 2TCLA 5D7WA 1CGEA 4WKIA 1KUFA 1MMRA 1XFWA 1G12A 2DW0A 3DSLA 1CAQA 1SATA 1KBCA 3DTKA 4H1QA 3CKIA 3DTIA 5L7FA 2OW9A 4IN9A 1Y8JA 1G49A 2OI0A 3LE9A 2X3AA 1L6JA 3KWVC 3LILA 2POJA 2MZHA 5I3MA 1JK3A 1PWVA 3LJGA 3F17A 3WV2A 4PKUA 3TVCA 1HTDA 4EFSA 1DTHA 4GR3A 4JIJA 3NX7A 3EDGA 2OY2A 1XFXA 2YB9A 1Q3AA 4ZR5A 1KUGA 1R1JA 2DW1A 2AIGP 5D1SA 3WV1A 2MLSA 3HY9A 3GBOA 1SMPA 4ILWD 1A86A 2XS4A 3DTEA 4GR0A 3DPFA 3TS4A 3E8RA 1PWWA 3B2ZA 2W15A 1XFZA 4AYKA 1R54A 1YQYA 2MZEA 1MMPA 2SRTA 2PJTA 5LABA 1XFYA 1JIWP 4GF1A 1OS2A 3HYGA 5B5OA 3ZXHA 3LQBA 2JT6A 5I4OA 5CUHA 1XM5A 1WNIA 3RTSA 1XAXA 1Y0VA 4XCTA 1XUDA 2Y6CA 1ZP5A 3LIRA 1XUCA 1G9KA 1XURA 3RTTA 1SLNA 1K7GA 4G9LA 2W12A 2O3EA 3VTGA 3V96B 4AIGA 1A85A 4H30A 4IJOA 1R1HA 1XFVA 1BIWA 1K7QA 1MMBA 2CLTA 1PWUA 1Z3JA 2AYKA 1EAKA 3EDIA 2ERQA 4FU4A 4XM7A 1RMZA 3KECA 1I76A 3Q2HA 4J4MA 3HBUP 2A8HA 1H71P 3F19A 3LUNA 5B5PA 5I12A 3KEJA 1BM6A 3LMCA 1EB6A 4JPAA 4HMAA 5BPAA 2USNA
chains in the Genus database with same CATH topology
3KRYA 5D1UA 2J83A 2KRJA 3EHYA 1OMJA 2V4BA 3K7NA 3ZUKA 2X7MA 1D8MA 4AXQA 3F1AA 1AKLA 4A7BA 1HY7A 3MA2A 1CXVA 3EHXA 2OXZA 1CGLA 3P1VA 4PKQA 1SU3A 5L79A 1DMTA 4L6TA 1ZS0A 1UTTA 2HU6A 3LGPA 1JANA 4WZVA 2CKIA 5BOYA 1OO9A 1BQQM 3I7GA 2L0RA 1CGFA 1SRPA 1QIBA 1FLSA 1USNA 4GR8A 5CXAA 1J7NA 5D3CA 1B8YA 3LK8A 2JT5A 4JP4A 1EUBA 1GO7P 830CA 4JQGA 4AUOA 1JIZA 3WV3A 1OS9A 1GE6A 1UTZA 1UMTA 5H8XA 2O36A 3G42A 3AYKA 1IAEA 4IUWA 2OW1A 3LJZA 4FXQA 1OM6A 3F15A 3G5CA 3B92A 4DF9A 3LJTA 2OY4A 2Z2DA 3EWJA 1D8FA 456CA 1OM7A 2YIGA 3UVCA 2Y6DA 1QIAA 4GWNA 1ZXVA 3LQ0A 4DPEA 2RJQA 4GWMA 3BA0A 1BQOA 4FXYP 3I7IA 2WOAA 2MLRA 1IAAA 2W13A 1HFCA 3USNA 3ZVSA 1JH1A 4R3VA 1RM8A 5I0LA 1GO8P 3P24A 1KAPP 2W14A 1MNCA 1GKDA 1O0QA 4DV8A 1QJJA 3DWBA 2E2DA 2WO8A 4DD8A 3OHOA 1FM1A 1CK7A 2X3BA 4A3WA 1IABA 4FVLA 1ATLA 3LKAA 2YUFA 1CQRA 1XFUA 5D2BA 1I73A 3AIGA 2J0TA 4L7AA 4PKTA 5JMYA 1I1IP 2OXUA 3HB2P 3LIKA 1JJ9A 2WO9A 1UEAA 1GKCA 1R1IA 1Y93A 2D1OA 4G0DA 3EDHA 1AYKA 2N8RA 2DDFA 2ERPA 1QJIA 3HBVP 1GE5A 1PWQA 4WK7A 2EROA 2XS3A 3O64A 2X3CA 3KMCA 4H49A 3DL1A 1BKCA 1JKYA 2DW2A 1KUKA 1UMSA 1YOUA 1O0TA 3LUMA 1K7IA 3F18A 3N2VA 2I47A 1IADA 1C3IA 4XM8A 3KEKA 4GUYA 3N2UA 1D5JA 4L19A 2FV9A 1SLMA 3TSKA 1MMQA 4Q1LA 2OZRA 4I03A 4ON1A 3B8ZA 4H82A 5D1TA 2D1NA 3OHLA 1GXDA 2K2GA 1R55A 2JIHA 3F16A 4L63A 3DNGA 4HX3A 3VI1A 3L0TA 1BSWA 1HV5A 3U1RA 4H76A 1PWPA 2DDYA 3O2XA 2RJPA 1BUDA 1ASTA 4PKVA 1ZXCA 3AYUA 966CA 2JSDA 1BZSA 2OVXA 1C7KA 1JAOA 1BUVM 1B3DA 4XBHA 3HDAP 4PKRA 1GE7A 1ND1A 1FBLA 3Q2GA 1ZTQA 3SHIA 2QPJA 2OXWA 1HOVA 1ROSA 3EDZA 1JAPA 2K9CA 2OW0A 1IAGA 1YCMA 2FV5A 4WF6A 5CZMA 3HY7A 1AF0A 3TT4A 3KHIA 2MZIA 5BOTA 1IACA 4CTHA 1KUHA 2OVZA 1ZVXA 3KMEA 3LEAA 4H2EA 1C8TA 1CIZA 1QICA 3HDBA 3K7LA 3DPEA 5I2ZA 4I35A 1BKCE 4QKZA 2OW2A 1JAQA 2E3XA 3L0VA 5I43A 1QUAA 1HFSA 2JNPA 1YP1A 1KUIA 1D7XA 4JA1A 4PKWA 1S4BP 1G4KA 4PKSA 1BKCI 4H84A 4H3XA 4GQLA 4XM6A 2W0DA 1OM8A 1G05A 3ELMA 4WKEA 2TCLA 5D7WA 1CGEA 4WKIA 1KUFA 1MMRA 1XFWA 1G12A 2DW0A 3DSLA 1CAQA 1SATA 1KBCA 3DTKA 4H1QA 3CKIA 3DTIA 5L7FA 2OW9A 4IN9A 1Y8JA 1G49A 2OI0A 3LE9A 2X3AA 1L6JA 3KWVC 3LILA 2POJA 2MZHA 5I3MA 1JK3A 1PWVA 3LJGA 3F17A 3WV2A 4PKUA 3TVCA 1HTDA 4EFSA 1DTHA 4GR3A 4JIJA 3NX7A 3EDGA 2OY2A 1XFXA 2YB9A 1Q3AA 4ZR5A 1KUGA 1R1JA 2DW1A 2AIGP 5D1SA 3WV1A 2MLSA 3HY9A 3GBOA 1SMPA 4ILWD 1A86A 2XS4A 3DTEA 4GR0A 3DPFA 3TS4A 3E8RA 1PWWA 3B2ZA 2W15A 1XFZA 4AYKA 1R54A 1YQYA 2MZEA 1MMPA 2SRTA 2PJTA 5LABA 1XFYA 1JIWP 4GF1A 1OS2A 3HYGA 5B5OA 3ZXHA 3LQBA 2JT6A 5I4OA 5CUHA 1WNIA 3RTSA 1Y0VA 4XCTA 1XUDA 2Y6CA 1ZP5A 3LIRA 1XUCA 1G9KA 1XURA 3RTTA 1SLNA 1K7GA 4G9LA 2W12A 2O3EA 3VTGA 3V96B 4AIGA 1A85A 4H30A 4IJOA 1R1HA 1XFVA 1BIWA 1K7QA 1MMBA 2CLTA 1PWUA 1Z3JA 2AYKA 1EAKA 3EDIA 2ERQA 4FU4A 4XM7A 1RMZA 3KECA 1I76A 3Q2HA 4J4MA 3HBUP 2A8HA 1H71P 3F19A 3LUNA 5B5PA 5I12A 3KEJA 1BM6A 3LMCA 1EB6A 4JPAA 4HMAA 5BPAA 2USNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KRY A;  5D1U A;  2J83 A;  2KRJ A;  3EHY A;  1OMJ A;  2V4B A;  3K7N A;  3ZUK A;  2X7M A;  1D8M A;  4AXQ A;  3F1A A;  1AKL A;  4A7B A;  1HY7 A;  3MA2 A;  1CXV A;  3EHX A;  2OXZ A;  1CGL A;  3P1V A;  4PKQ A;  1SU3 A;  5L79 A;  1DMT A;  4L6T A;  1ZS0 A;  1UTT A;  2HU6 A;  3LGP A;  1JAN A;  4WZV A;  2CKI A;  5BOY A;  1OO9 A;  1BQQ M;  3I7G A;  2L0R A;  1CGF A;  1SRP A;  1QIB A;  1FLS A;  1USN A;  4GR8 A;  5CXA A;  1J7N A;  5D3C A;  1B8Y A;  3LK8 A;  2JT5 A;  4JP4 A;  1EUB A;  1GO7 P;  830C A;  4JQG A;  4AUO A;  1JIZ A;  3WV3 A;  1OS9 A;  1GE6 A;  1UTZ A;  1UMT A;  5H8X A;  2O36 A;  3G42 A;  3AYK A;  1IAE A;  4IUW A;  2OW1 A;  3LJZ A;  4FXQ A;  1OM6 A;  3F15 A;  3G5C A;  3B92 A;  4DF9 A;  3LJT A;  2OY4 A;  2Z2D A;  3EWJ A;  1D8F A;  456C A;  1OM7 A;  2YIG A;  3UVC A;  2Y6D A;  1QIA A;  4GWN A;  1ZXV A;  3LQ0 A;  4DPE A;  2RJQ A;  4GWM A;  3BA0 A;  1BQO A;  4FXY P;  3I7I A;  2WOA A;  2MLR A;  1IAA A;  2W13 A;  1HFC A;  3USN A;  3ZVS A;  1JH1 A;  4R3V A;  1RM8 A;  5I0L A;  1GO8 P;  3P24 A;  1KAP P;  2W14 A;  1MNC A;  1GKD A;  1O0Q A;  4DV8 A;  1QJJ A;  3DWB A;  2E2D A;  2WO8 A;  4DD8 A;  3OHO A;  1FM1 A;  1CK7 A;  2X3B A;  4A3W A;  1IAB A;  4FVL A;  1ATL A;  3LKA A;  1CQR A;  1XFU A;  5D2B A;  1I73 A;  3AIG A;  2J0T A;  4PKT A;  5JMY A;  1I1I P;  2OXU A;  3HB2 P;  3LIK A;  1JJ9 A;  2WO9 A;  1UEA A;  1GKC A;  1R1I A;  1Y93 A;  2D1O A;  4G0D A;  3EDH A;  1AYK A;  2N8R A;  2DDF A;  2ERP A;  1QJI A;  3HBV P;  1GE5 A;  1PWQ A;  4WK7 A;  2ERO A;  2XS3 A;  3O64 A;  2X3C A;  3KMC A;  4H49 A;  3DL1 A;  1BKC A;  1JKY A;  2DW2 A;  1KUK A;  1UMS A;  1YOU A;  1O0T A;  3LUM A;  1K7I A;  3F18 A;  3N2V A;  2I47 A;  1IAD A;  1C3I A;  4XM8 A;  3KEK A;  4GUY A;  3N2U A;  1D5J A;  4L19 A;  2FV9 A;  1SLM A;  3TSK A;  1MMQ A;  4Q1L A;  2OZR A;  4I03 A;  4ON1 A;  3B8Z A;  4H82 A;  5D1T A;  2D1N A;  3OHL A;  1GXD A;  2K2G A;  1R55 A;  2JIH A;  3F16 A;  4L63 A;  3DNG A;  4HX3 A;  3VI1 A;  3L0T A;  1BSW A;  1HV5 A;  3U1R A;  4H76 A;  1PWP A;  2DDY A;  3O2X A;  2RJP A;  1BUD A;  1AST A;  4PKV A;  1ZXC A;  3AYU A;  966C A;  2JSD A;  1BZS A;  2OVX A;  1C7K A;  1JAO A;  1BUV M;  1B3D A;  4XBH A;  3HDA P;  4PKR A;  1GE7 A;  1ND1 A;  1FBL A;  3Q2G A;  1ZTQ A;  3SHI A;  2QPJ A;  2OXW A;  1HOV A;  1ROS A;  3EDZ A;  1JAP A;  2K9C A;  2OW0 A;  1IAG A;  1YCM A;  2FV5 A;  4WF6 A;  5CZM A;  3HY7 A;  1AF0 A;  3TT4 A;  3KHI A;  2MZI A;  5BOT A;  1IAC A;  4CTH A;  1KUH A;  2OVZ A;  1ZVX A;  3KME A;  3LEA A;  4H2E A;  1C8T A;  1CIZ A;  1QIC A;  3HDB A;  3K7L A;  3DPE A;  5I2Z A;  4I35 A;  1BKC E;  4QKZ A;  2OW2 A;  1JAQ A;  2E3X A;  3L0V A;  5I43 A;  1QUA A;  1HFS A;  2JNP A;  1YP1 A;  1KUI A;  1D7X A;  4JA1 A;  4PKW A;  1S4B P;  1G4K A;  4PKS A;  1BKC I;  4H84 A;  4H3X A;  4GQL A;  4XM6 A;  2W0D A;  1OM8 A;  1G05 A;  3ELM A;  4WKE A;  2TCL A;  5D7W A;  1CGE A;  4WKI A;  1KUF A;  1MMR A;  1XFW A;  1G12 A;  2DW0 A;  3DSL A;  1CAQ A;  1SAT A;  1KBC A;  4H1Q A;  3CKI A;  5L7F A;  2OW9 A;  4IN9 A;  1Y8J A;  1G49 A;  2OI0 A;  3LE9 A;  2X3A A;  1L6J A;  3KWV C;  3LIL A;  2POJ A;  2MZH A;  5I3M A;  1JK3 A;  1PWV A;  3LJG A;  3F17 A;  3WV2 A;  4PKU A;  3TVC A;  1HTD A;  4EFS A;  1DTH A;  4GR3 A;  4JIJ A;  3NX7 A;  3EDG A;  2OY2 A;  1XFX A;  2YB9 A;  1Q3A A;  4ZR5 A;  1KUG A;  1R1J A;  2DW1 A;  2AIG P;  5D1S A;  3WV1 A;  2MLS A;  3HY9 A;  3GBO A;  1SMP A;  4ILW D;  1A86 A;  2XS4 A;  4GR0 A;  3DPF A;  3TS4 A;  3E8R A;  1PWW A;  3B2Z A;  2W15 A;  1XFZ A;  4AYK A;  1R54 A;  1YQY A;  2MZE A;  1MMP A;  2SRT A;  2PJT A;  5LAB A;  1XFY A;  1JIW P;  4GF1 A;  1OS2 A;  3HYG A;  5B5O A;  3ZXH A;  3LQB A;  2JT6 A;  5I4O A;  5CUH A;  1WNI A;  3RTS A;  1Y0V A;  4XCT A;  1XUD A;  2Y6C A;  1ZP5 A;  3LIR A;  1XUC A;  1G9K A;  1XUR A;  3RTT A;  1SLN A;  1K7G A;  4G9L A;  2W12 A;  2O3E A;  3VTG A;  3V96 B;  4AIG A;  1A85 A;  4H30 A;  4IJO A;  1R1H A;  1XFV A;  1BIW A;  1K7Q A;  1MMB A;  2CLT A;  1PWU A;  1Z3J A;  2AYK A;  1EAK A;  3EDI A;  2ERQ A;  4FU4 A;  4XM7 A;  1RMZ A;  3KEC A;  1I76 A;  3Q2H A;  4J4M A;  3HBU P;  2A8H A;  1H71 P;  3F19 A;  3LUN A;  5B5P A;  5I12 A;  3KEJ A;  1BM6 A;  3LMC A;  1EB6 A;  4JPA A;  4HMA A;  5BPA A;  2USN A; 
#chains in the Genus database with same CATH topology
 3KRY A;  5D1U A;  2J83 A;  2KRJ A;  3EHY A;  1OMJ A;  2V4B A;  3K7N A;  3ZUK A;  2X7M A;  1D8M A;  4AXQ A;  3F1A A;  1AKL A;  4A7B A;  1HY7 A;  3MA2 A;  1CXV A;  3EHX A;  2OXZ A;  1CGL A;  3P1V A;  4PKQ A;  1SU3 A;  5L79 A;  1DMT A;  4L6T A;  1ZS0 A;  1UTT A;  2HU6 A;  3LGP A;  1JAN A;  4WZV A;  2CKI A;  5BOY A;  1OO9 A;  1BQQ M;  3I7G A;  2L0R A;  1CGF A;  1SRP A;  1QIB A;  1FLS A;  1USN A;  4GR8 A;  5CXA A;  1J7N A;  5D3C A;  1B8Y A;  3LK8 A;  1TVI A;  2JT5 A;  4JP4 A;  1EUB A;  1GO7 P;  830C A;  4JQG A;  4AUO A;  1JIZ A;  3WV3 A;  1OS9 A;  1GE6 A;  1UTZ A;  1UMT A;  5H8X A;  2O36 A;  3G42 A;  3AYK A;  1IAE A;  4IUW A;  2OW1 A;  3LJZ A;  4FXQ A;  1OM6 A;  3F15 A;  3G5C A;  3B92 A;  4DF9 A;  3LJT A;  2OY4 A;  2Z2D A;  3EWJ A;  1D8F A;  456C A;  1OM7 A;  2YIG A;  3UVC A;  2Y6D A;  1QIA A;  4GWN A;  1ZXV A;  3LQ0 A;  4DPE A;  2RJQ A;  4GWM A;  3BA0 A;  1BQO A;  4FXY P;  3I7I A;  2WOA A;  2MLR A;  1IAA A;  2W13 A;  1HFC A;  3USN A;  3ZVS A;  1JH1 A;  4R3V A;  1RM8 A;  5I0L A;  1GO8 P;  3P24 A;  1KAP P;  2W14 A;  1MNC A;  1GKD A;  1O0Q A;  4DV8 A;  1QJJ A;  3DWB A;  2E2D A;  2WO8 A;  4DD8 A;  3OHO A;  1FM1 A;  1CK7 A;  2X3B A;  4A3W A;  1IAB A;  4FVL A;  1ATL A;  3LKA A;  2YUF A;  1CQR A;  1XFU A;  5D2B A;  1I73 A;  3AIG A;  2J0T A;  4L7A A;  4PKT A;  5JMY A;  1I1I P;  2OXU A;  3HB2 P;  3LIK A;  1JJ9 A;  2WO9 A;  1UEA A;  1GKC A;  1R1I A;  1Y93 A;  2D1O A;  4G0D A;  3EDH A;  1AYK A;  2N8R A;  2DDF A;  2ERP A;  1QJI A;  3HBV P;  1GE5 A;  1PWQ A;  4WK7 A;  2ERO A;  2XS3 A;  3O64 A;  2X3C A;  3KMC A;  4H49 A;  3DL1 A;  1BKC A;  1JKY A;  2DW2 A;  1KUK A;  1UMS A;  1YOU A;  1O0T A;  3LUM A;  1K7I A;  3F18 A;  3N2V A;  2I47 A;  1IAD A;  1C3I A;  4XM8 A;  3KEK A;  4GUY A;  3N2U A;  1D5J A;  4L19 A;  2FV9 A;  1SLM A;  3TSK A;  1MMQ A;  4Q1L A;  2OZR A;  4I03 A;  4ON1 A;  3B8Z A;  4H82 A;  5D1T A;  2D1N A;  3OHL A;  1GXD A;  2K2G A;  1R55 A;  2JIH A;  3F16 A;  4L63 A;  3DNG A;  4HX3 A;  3VI1 A;  3L0T A;  1BSW A;  1HV5 A;  3U1R A;  4H76 A;  1PWP A;  2DDY A;  3O2X A;  2RJP A;  1BUD A;  1AST A;  4PKV A;  1ZXC A;  3AYU A;  966C A;  2JSD A;  1BZS A;  2OVX A;  1C7K A;  1JAO A;  1BUV M;  1B3D A;  4XBH A;  3HDA P;  4PKR A;  1GE7 A;  1ND1 A;  1FBL A;  3Q2G A;  1ZTQ A;  3SHI A;  2QPJ A;  2OXW A;  1HOV A;  1ROS A;  3EDZ A;  1JAP A;  2K9C A;  2OW0 A;  1IAG A;  1YCM A;  2FV5 A;  4WF6 A;  5CZM A;  3HY7 A;  1AF0 A;  3TT4 A;  3KHI A;  2MZI A;  5BOT A;  1IAC A;  4CTH A;  1KUH A;  2OVZ A;  1ZVX A;  3KME A;  3LEA A;  4H2E A;  1C8T A;  1CIZ A;  1QIC A;  3HDB A;  3K7L A;  3DPE A;  5I2Z A;  4I35 A;  1BKC E;  4QKZ A;  2OW2 A;  1JAQ A;  2E3X A;  3L0V A;  5I43 A;  1QUA A;  1HFS A;  1OZ9 A;  2JNP A;  1YP1 A;  1KUI A;  1D7X A;  4JA1 A;  4PKW A;  1S4B P;  1G4K A;  4PKS A;  1BKC I;  4H84 A;  4H3X A;  4GQL A;  4XM6 A;  2W0D A;  1OM8 A;  1G05 A;  3ELM A;  4WKE A;  2TCL A;  5D7W A;  1CGE A;  4WKI A;  1KUF A;  1MMR A;  1XFW A;  1G12 A;  2DW0 A;  3DSL A;  1CAQ A;  1SAT A;  1KBC A;  3DTK A;  4H1Q A;  3CKI A;  3DTI A;  5L7F A;  2OW9 A;  4IN9 A;  1Y8J A;  1G49 A;  2OI0 A;  3LE9 A;  2X3A A;  1L6J A;  3KWV C;  3LIL A;  2POJ A;  2MZH A;  5I3M A;  1JK3 A;  1PWV A;  3LJG A;  3F17 A;  3WV2 A;  4PKU A;  3TVC A;  1HTD A;  4EFS A;  1DTH A;  4GR3 A;  4JIJ A;  3NX7 A;  3EDG A;  2OY2 A;  1XFX A;  2YB9 A;  1Q3A A;  4ZR5 A;  1KUG A;  1R1J A;  2DW1 A;  2AIG P;  5D1S A;  3WV1 A;  2MLS A;  3HY9 A;  3GBO A;  1SMP A;  4ILW D;  1A86 A;  2XS4 A;  3DTE A;  4GR0 A;  3DPF A;  3TS4 A;  3E8R A;  1PWW A;  3B2Z A;  2W15 A;  1XFZ A;  4AYK A;  1R54 A;  1YQY A;  2MZE A;  1MMP A;  2SRT A;  2PJT A;  5LAB A;  1XFY A;  1JIW P;  4GF1 A;  1OS2 A;  3HYG A;  5B5O A;  3ZXH A;  3LQB A;  2JT6 A;  5I4O A;  5CUH A;  1XM5 A;  1WNI A;  3RTS A;  1XAX A;  1Y0V A;  4XCT A;  1XUD A;  2Y6C A;  1ZP5 A;  3LIR A;  1XUC A;  1G9K A;  1XUR A;  3RTT A;  1SLN A;  1K7G A;  4G9L A;  2W12 A;  2O3E A;  3VTG A;  3V96 B;  4AIG A;  1A85 A;  4H30 A;  4IJO A;  1R1H A;  1XFV A;  1BIW A;  1K7Q A;  1MMB A;  2CLT A;  1PWU A;  1Z3J A;  2AYK A;  1EAK A;  3EDI A;  2ERQ A;  4FU4 A;  4XM7 A;  1RMZ A;  3KEC A;  1I76 A;  3Q2H A;  4J4M A;  3HBU P;  2A8H A;  1H71 P;  3F19 A;  3LUN A;  5B5P A;  5I12 A;  3KEJ A;  1BM6 A;  3LMC A;  1EB6 A;  4JPA A;  4HMA A;  5BPA A;  2USN A; 
#chains in the Genus database with same CATH homology
 3KRY A;  5D1U A;  2J83 A;  2KRJ A;  3EHY A;  1OMJ A;  2V4B A;  3K7N A;  3ZUK A;  2X7M A;  1D8M A;  4AXQ A;  3F1A A;  1AKL A;  4A7B A;  1HY7 A;  3MA2 A;  1CXV A;  3EHX A;  2OXZ A;  1CGL A;  3P1V A;  4PKQ A;  1SU3 A;  5L79 A;  1DMT A;  4L6T A;  1ZS0 A;  1UTT A;  2HU6 A;  3LGP A;  1JAN A;  4WZV A;  2CKI A;  5BOY A;  1OO9 A;  1BQQ M;  3I7G A;  2L0R A;  1CGF A;  1SRP A;  1QIB A;  1FLS A;  1USN A;  4GR8 A;  5CXA A;  1J7N A;  5D3C A;  1B8Y A;  3LK8 A;  2JT5 A;  4JP4 A;  1EUB A;  1GO7 P;  830C A;  4JQG A;  4AUO A;  1JIZ A;  3WV3 A;  1OS9 A;  1GE6 A;  1UTZ A;  1UMT A;  5H8X A;  2O36 A;  3G42 A;  3AYK A;  1IAE A;  4IUW A;  2OW1 A;  3LJZ A;  4FXQ A;  1OM6 A;  3F15 A;  3G5C A;  3B92 A;  4DF9 A;  3LJT A;  2OY4 A;  2Z2D A;  3EWJ A;  1D8F A;  456C A;  1OM7 A;  2YIG A;  3UVC A;  2Y6D A;  1QIA A;  4GWN A;  1ZXV A;  3LQ0 A;  4DPE A;  2RJQ A;  4GWM A;  3BA0 A;  1BQO A;  4FXY P;  3I7I A;  2WOA A;  2MLR A;  1IAA A;  2W13 A;  1HFC A;  3USN A;  3ZVS A;  1JH1 A;  4R3V A;  1RM8 A;  5I0L A;  1GO8 P;  3P24 A;  1KAP P;  2W14 A;  1MNC A;  1GKD A;  1O0Q A;  4DV8 A;  1QJJ A;  3DWB A;  2E2D A;  2WO8 A;  4DD8 A;  3OHO A;  1FM1 A;  1CK7 A;  2X3B A;  4A3W A;  1IAB A;  4FVL A;  1ATL A;  3LKA A;  2YUF A;  1CQR A;  1XFU A;  5D2B A;  1I73 A;  3AIG A;  2J0T A;  4L7A A;  4PKT A;  5JMY A;  1I1I P;  2OXU A;  3HB2 P;  3LIK A;  1JJ9 A;  2WO9 A;  1UEA A;  1GKC A;  1R1I A;  1Y93 A;  2D1O A;  4G0D A;  3EDH A;  1AYK A;  2N8R A;  2DDF A;  2ERP A;  1QJI A;  3HBV P;  1GE5 A;  1PWQ A;  4WK7 A;  2ERO A;  2XS3 A;  3O64 A;  2X3C A;  3KMC A;  4H49 A;  3DL1 A;  1BKC A;  1JKY A;  2DW2 A;  1KUK A;  1UMS A;  1YOU A;  1O0T A;  3LUM A;  1K7I A;  3F18 A;  3N2V A;  2I47 A;  1IAD A;  1C3I A;  4XM8 A;  3KEK A;  4GUY A;  3N2U A;  1D5J A;  4L19 A;  2FV9 A;  1SLM A;  3TSK A;  1MMQ A;  4Q1L A;  2OZR A;  4I03 A;  4ON1 A;  3B8Z A;  4H82 A;  5D1T A;  2D1N A;  3OHL A;  1GXD A;  2K2G A;  1R55 A;  2JIH A;  3F16 A;  4L63 A;  3DNG A;  4HX3 A;  3VI1 A;  3L0T A;  1BSW A;  1HV5 A;  3U1R A;  4H76 A;  1PWP A;  2DDY A;  3O2X A;  2RJP A;  1BUD A;  1AST A;  4PKV A;  1ZXC A;  3AYU A;  966C A;  2JSD A;  1BZS A;  2OVX A;  1C7K A;  1JAO A;  1BUV M;  1B3D A;  4XBH A;  3HDA P;  4PKR A;  1GE7 A;  1ND1 A;  1FBL A;  3Q2G A;  1ZTQ A;  3SHI A;  2QPJ A;  2OXW A;  1HOV A;  1ROS A;  3EDZ A;  1JAP A;  2K9C A;  2OW0 A;  1IAG A;  1YCM A;  2FV5 A;  4WF6 A;  5CZM A;  3HY7 A;  1AF0 A;  3TT4 A;  3KHI A;  2MZI A;  5BOT A;  1IAC A;  4CTH A;  1KUH A;  2OVZ A;  1ZVX A;  3KME A;  3LEA A;  4H2E A;  1C8T A;  1CIZ A;  1QIC A;  3HDB A;  3K7L A;  3DPE A;  5I2Z A;  4I35 A;  1BKC E;  4QKZ A;  2OW2 A;  1JAQ A;  2E3X A;  3L0V A;  5I43 A;  1QUA A;  1HFS A;  2JNP A;  1YP1 A;  1KUI A;  1D7X A;  4JA1 A;  4PKW A;  1S4B P;  1G4K A;  4PKS A;  1BKC I;  4H84 A;  4H3X A;  4GQL A;  4XM6 A;  2W0D A;  1OM8 A;  1G05 A;  3ELM A;  4WKE A;  2TCL A;  5D7W A;  1CGE A;  4WKI A;  1KUF A;  1MMR A;  1XFW A;  1G12 A;  2DW0 A;  3DSL A;  1CAQ A;  1SAT A;  1KBC A;  3DTK A;  4H1Q A;  3CKI A;  3DTI A;  5L7F A;  2OW9 A;  4IN9 A;  1Y8J A;  1G49 A;  2OI0 A;  3LE9 A;  2X3A A;  1L6J A;  3KWV C;  3LIL A;  2POJ A;  2MZH A;  5I3M A;  1JK3 A;  1PWV A;  3LJG A;  3F17 A;  3WV2 A;  4PKU A;  3TVC A;  1HTD A;  4EFS A;  1DTH A;  4GR3 A;  4JIJ A;  3NX7 A;  3EDG A;  2OY2 A;  1XFX A;  2YB9 A;  1Q3A A;  4ZR5 A;  1KUG A;  1R1J A;  2DW1 A;  2AIG P;  5D1S A;  3WV1 A;  2MLS A;  3HY9 A;  3GBO A;  1SMP A;  4ILW D;  1A86 A;  2XS4 A;  3DTE A;  4GR0 A;  3DPF A;  3TS4 A;  3E8R A;  1PWW A;  3B2Z A;  2W15 A;  1XFZ A;  4AYK A;  1R54 A;  1YQY A;  2MZE A;  1MMP A;  2SRT A;  2PJT A;  5LAB A;  1XFY A;  1JIW P;  4GF1 A;  1OS2 A;  3HYG A;  5B5O A;  3ZXH A;  3LQB A;  2JT6 A;  5I4O A;  5CUH A;  1WNI A;  3RTS A;  1Y0V A;  4XCT A;  1XUD A;  2Y6C A;  1ZP5 A;  3LIR A;  1XUC A;  1G9K A;  1XUR A;  3RTT A;  1SLN A;  1K7G A;  4G9L A;  2W12 A;  2O3E A;  3VTG A;  3V96 B;  4AIG A;  1A85 A;  4H30 A;  4IJO A;  1R1H A;  1XFV A;  1BIW A;  1K7Q A;  1MMB A;  2CLT A;  1PWU A;  1Z3J A;  2AYK A;  1EAK A;  3EDI A;  2ERQ A;  4FU4 A;  4XM7 A;  1RMZ A;  3KEC A;  1I76 A;  3Q2H A;  4J4M A;  3HBU P;  2A8H A;  1H71 P;  3F19 A;  3LUN A;  5B5P A;  5I12 A;  3KEJ A;  1BM6 A;  3LMC A;  1EB6 A;  4JPA A;  4HMA A;  5BPA A;  2USN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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