4A7BA

Mmp13 in complex with a novel selective non zinc binding inhibitor cmpd22
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
169
structure length
169
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords COLLAGENASE 3
publication title Lead Optimisation of Selective Non-Zinc Binding Inhibitors of Mmp13. Part 2.
pubmed doi rcsb
source organism Homo sapiens
total genus 47
structure length 169
sequence length 169
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2011-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4a7bA00
1A85A 1XUDA 5BOTA 2W12A 1KUGA 1Y8JA 3F17A 2OW2A 2MZHA 3EDIA 4H1QA 1JKYA 2D1OA 3DNGA 1BKCI 1OS2A 4IN9A 1BM6A 2USNA 1PWVA 3WV2A 3Q2GA 3KMCA 1C8TA 2OVZA 4GR0A 1CXVA 1OS9A 4G0DA 1CQRA 3F16A 4JIJA 4FXQA 1OMJA 4PKQA 1XFUA 1L6JA 2YIGA 1OM8A 1MMQA 3LQ0A 4DV8A 1HTDA 3K7LA 1XURA 2OXZA 1PWUA 1XUCA 2MLSA 3L0VA 1ZTQA 4GR8A 2X3CA 4QKZA 3HDAP 1CGEA 2MLRA 1Y0VA 1XFVA 4JA1A 2O3EA 1JH1A 5H8XA 4WKEA 456CA 2EROA 3GBOA 1QIBA 3KECA 5LABA 4A7BA 1OO9A 5JMYA 1GE5A 1KUIA 2WO9A 2X7MA 3EWJA 5I2ZA 5I4OA 4AYKA 5I0LA 1ZXCA 2SRTA 1QICA 4AIGA 3F15A 2RJPA 1BQOA 3E8RA 1B8YA 2V4BA 3I7GA 4H49A 1MMPA 1RM8A 1XFWA 3UVCA 1BKCA 1KUKA 1BIWA 4PKVA 3TSKA 1D8MA 1UTZA 1BUDA 1QJJA 1A86A 3DWBA 1GO8P 3EDZA 4IUWA 1USNA 1IAAA 3LQBA 1ND1A 2DDYA 5I12A 1MMRA 4XM6A 4PKUA 2POJA 1DTHA 1C7KA 3LIKA 3F18A 5CZMA 1Y93A 4DPEA 3B2ZA 3KWVC 3TT4A 1FM1A 3Q2HA 1D7XA 4H2EA 2W13A 1KUHA 4WKIA 5I43A 3O2XA 4ILWD 3LIRA 1JAPA 4JQGA 1XFXA 4H76A 1R1HA 5D1TA 1GXDA 4JPAA 1ZS0A 2RJQA 3BA0A 1PWQA 3ZXHA 1ZVXA 1R54A 1O0QA 2DDFA 2JNPA 1S4BP 4R3VA 1GE6A 3LUNA 1SRPA 1K7IA 3RTTA 1O0TA 4IJOA 1GE7A 3VTGA 4XBHA 1OM7A 2L0RA 1UMTA 1JIWP 2K2GA 1B3DA 1XFZA 4ON1A 1OM6A 3KRYA 2KRJA 2OI0A 3OHOA 1BSWA 1UMSA 3HBUP 1AKLA 1GKDA 1MNCA 4GF1A 3DPEA 1PWPA 1K7QA 2X3BA 2E2DA 3AIGA 3V96B 4H3XA 4A3WA 5I3MA 2MZIA 3MA2A 4DD8A 2CLTA 1BQQM 2A8HA 2O36A 4XCTA 4ZR5A 3KMEA 2W15A 2OW0A 4I03A 3HB2P 3P1VA 3LEAA 2OVXA 2MZEA 3EDHA 2OW9A 3HDBA 2OXUA 4EFSA 1JAQA 4WK7A 1GO7P 4PKRA 4PKTA 1DMTA 1QIAA 3N2UA 2QPJA 1H71P 2D1NA 5L7FA 1UTTA 1IAGA 1GKCA 3P24A 4G9LA 2Y6DA 5L79A 1C3IA 5D1UA 3HYGA 1EAKA 1CGLA 1G4KA 1SLMA 4HMAA 3DL1A 3DSLA 1HV5A 2ERQA 1UEAA 3I7IA 1CGFA 5CUHA 1IABA 3LK8A 1BZSA 5B5OA 3O64A 4JP4A 3USNA 2XS3A 3WV1A 2E3XA 1R55A 2OW1A 1YP1A 4I35A 1EB6A 5D1SA 1RMZA 3TVCA 4GUYA 1AF0A 1MMBA 4GWMA 3KHIA 2X3AA 1J7NA 2TCLA 3AYKA 4L63A 2XS4A 3G5CA 3LILA 3SHIA 966CA 2FV9A 2DW0A 1QUAA 3NX7A 4H84A 4XM8A 1D8FA 5D3CA 4FVLA 2W0DA 2WOAA 1HOVA 2Y6CA 2I47A 5D7WA 1R1IA 3LJTA 3OHLA 4L6TA 3HY7A 1I73A 2OXWA 3TS4A 1QJIA 3LE9A 4WZVA 1SATA 5BPAA 3LUMA 1CIZA 1I1IP 2OY4A 3ELMA 1BKCE 2JT5A 3AYUA 4GR3A 1IAEA 3DPFA 1KUFA 3L0TA 4H30A 4XM7A 830CA 3F1AA 2CKIA 1KAPP 1JIZA 1SMPA 4Q1LA 1CK7A 4DF9A 4FXYP 1G05A 4GQLA 1G49A 2W14A 3B92A 1IACA 3LKAA 3N2VA 1ASTA 3K7NA 1JJ9A 5B5PA 3EHYA 1YQYA 1ATLA 3VI1A 3U1RA 1EUBA 1D5JA 4J4MA 3EHXA 2DW2A 4CTHA 4PKWA 3RTSA 3HY9A 5BOYA 1JK3A 2J0TA 2YB9A 2JT6A 4PKSA 3LGPA 1IADA 2AIGP 4AXQA 4HX3A 1HFSA 1YCMA 3LJZA 1K7GA 3B8ZA 1PWWA 1Q3AA 2OY2A 1ZP5A 1HY7A 4L19A 3F19A 2N8RA 3ZUKA 4FU4A 3KEKA 1JAOA 2K9CA 5CXAA 1SLNA 3LMCA 1JANA 4GWNA 3LJGA 3G42A 1ROSA 2JSDA 2FV5A 1R1JA 4WF6A 1HFCA 1CAQA 1YOUA 1G9KA 1AYKA 2WO8A 2JIHA 3EDGA 1FBLA 3HBVP 2OZRA 2Z2DA 3ZVSA 5D2BA 2AYKA 3WV3A 1XFYA 4AUOA 2ERPA 1KBCA 3CKIA 2J83A 1I76A 1ZXVA 4H82A 1BUVM 1FLSA 1SU3A 2HU6A 2DW1A 1Z3JA 2PJTA 1WNIA 3KEJA 1G12A
chains in the Genus database with same CATH superfamily
1A85A 1XUDA 5BOTA 2W12A 1KUGA 1Y8JA 3F17A 2OW2A 2MZHA 3DTKA 3EDIA 4H1QA 1JKYA 2D1OA 3DNGA 1BKCI 1OS2A 4IN9A 1BM6A 2USNA 1PWVA 3WV2A 3Q2GA 3KMCA 1C8TA 2OVZA 4GR0A 1CXVA 1OS9A 4G0DA 1CQRA 3F16A 4JIJA 4FXQA 1OMJA 4PKQA 1XFUA 1L6JA 2YIGA 1OM8A 1MMQA 3LQ0A 4DV8A 1HTDA 3DTEA 3K7LA 1XURA 2OXZA 1PWUA 1XUCA 2MLSA 3L0VA 1ZTQA 4GR8A 2X3CA 4QKZA 3HDAP 1CGEA 2MLRA 1Y0VA 1XFVA 4JA1A 2O3EA 1JH1A 5H8XA 4WKEA 456CA 2EROA 3GBOA 1QIBA 3KECA 5LABA 4A7BA 1OO9A 5JMYA 1GE5A 1KUIA 2WO9A 2X7MA 3EWJA 5I2ZA 5I4OA 4AYKA 5I0LA 1ZXCA 2SRTA 1QICA 4AIGA 3F15A 2RJPA 1BQOA 3E8RA 1B8YA 2V4BA 3I7GA 4H49A 1MMPA 1RM8A 1XFWA 3UVCA 1BKCA 1KUKA 1BIWA 4PKVA 3TSKA 1D8MA 1UTZA 1BUDA 1QJJA 1A86A 3DWBA 1GO8P 3EDZA 4IUWA 1USNA 1IAAA 3LQBA 1ND1A 2DDYA 5I12A 1MMRA 4XM6A 4PKUA 2POJA 1DTHA 1C7KA 3LIKA 3F18A 5CZMA 1Y93A 4DPEA 3B2ZA 3KWVC 3TT4A 1FM1A 3Q2HA 1D7XA 4H2EA 2W13A 1KUHA 4WKIA 5I43A 3O2XA 4ILWD 3LIRA 1JAPA 4JQGA 1XFXA 4H76A 1R1HA 5D1TA 1GXDA 4JPAA 1ZS0A 2RJQA 3BA0A 1PWQA 3ZXHA 1ZVXA 1R54A 3DTIA 1O0QA 2DDFA 2JNPA 1S4BP 4R3VA 1GE6A 3LUNA 1SRPA 1K7IA 3RTTA 1O0TA 4IJOA 1GE7A 3VTGA 4XBHA 1OM7A 2L0RA 1UMTA 1JIWP 2K2GA 1B3DA 1XFZA 4ON1A 1OM6A 3KRYA 2KRJA 2OI0A 3OHOA 1BSWA 1UMSA 3HBUP 1AKLA 1GKDA 1MNCA 4GF1A 3DPEA 1PWPA 1K7QA 2X3BA 2E2DA 3AIGA 1XAXA 3V96B 4H3XA 4A3WA 5I3MA 2MZIA 3MA2A 4DD8A 2CLTA 1BQQM 2A8HA 2O36A 4XCTA 4ZR5A 3KMEA 2W15A 2OW0A 4I03A 3HB2P 3P1VA 3LEAA 2OVXA 2MZEA 3EDHA 2OW9A 3HDBA 2OXUA 4EFSA 1JAQA 4WK7A 1GO7P 4PKRA 4PKTA 1DMTA 1QIAA 3N2UA 2QPJA 1H71P 1OZ9A 2D1NA 5L7FA 1UTTA 1IAGA 1GKCA 3P24A 4G9LA 2Y6DA 5L79A 1C3IA 5D1UA 3HYGA 1EAKA 1CGLA 1G4KA 1SLMA 4HMAA 3DL1A 3DSLA 1HV5A 2ERQA 1UEAA 3I7IA 1CGFA 5CUHA 1IABA 3LK8A 1BZSA 5B5OA 3O64A 4JP4A 3USNA 2XS3A 3WV1A 2E3XA 1R55A 2OW1A 1YP1A 4L7AA 4I35A 1EB6A 5D1SA 1RMZA 3TVCA 4GUYA 1AF0A 1MMBA 4GWMA 3KHIA 2X3AA 1J7NA 2TCLA 3AYKA 4L63A 2XS4A 3G5CA 3LILA 2YUFA 3SHIA 966CA 2FV9A 2DW0A 1QUAA 3NX7A 4H84A 4XM8A 1D8FA 5D3CA 4FVLA 2W0DA 2WOAA 1HOVA 2Y6CA 2I47A 5D7WA 1R1IA 3LJTA 3OHLA 4L6TA 3HY7A 1I73A 2OXWA 3TS4A 1QJIA 3LE9A 4WZVA 1SATA 1XM5A 5BPAA 3LUMA 1CIZA 1I1IP 2OY4A 3ELMA 1BKCE 2JT5A 3AYUA 4GR3A 1IAEA 3DPFA 1KUFA 3L0TA 4H30A 4XM7A 830CA 3F1AA 2CKIA 1KAPP 1JIZA 1SMPA 4Q1LA 1CK7A 4DF9A 4FXYP 1G05A 4GQLA 1G49A 2W14A 3B92A 1IACA 3LKAA 3N2VA 1ASTA 3K7NA 1JJ9A 5B5PA 3EHYA 1YQYA 1ATLA 3VI1A 3U1RA 1EUBA 1D5JA 4J4MA 3EHXA 2DW2A 4CTHA 4PKWA 3RTSA 3HY9A 5BOYA 1JK3A 2J0TA 2YB9A 2JT6A 4PKSA 3LGPA 1IADA 2AIGP 4AXQA 4HX3A 1HFSA 1YCMA 3LJZA 1K7GA 3B8ZA 1PWWA 1Q3AA 2OY2A 1ZP5A 1HY7A 4L19A 3F19A 2N8RA 3ZUKA 4FU4A 3KEKA 1JAOA 2K9CA 5CXAA 1SLNA 3LMCA 1JANA 4GWNA 3LJGA 3G42A 1ROSA 2JSDA 2FV5A 1R1JA 4WF6A 1HFCA 1CAQA 1YOUA 1G9KA 1AYKA 2WO8A 2JIHA 3EDGA 1FBLA 3HBVP 2OZRA 1TVIA 2Z2DA 3ZVSA 5D2BA 2AYKA 3WV3A 1XFYA 4AUOA 2ERPA 1KBCA 3CKIA 2J83A 1I76A 1ZXVA 4H82A 1BUVM 1FLSA 1SU3A 2HU6A 2DW1A 1Z3JA 2PJTA 1WNIA 3KEJA 1G12A
chains in the Genus database with same CATH topology
1A85A 1XUDA 5BOTA 2W12A 1KUGA 1Y8JA 3F17A 2OW2A 2MZHA 3DTKA 3EDIA 4H1QA 1JKYA 2D1OA 3DNGA 1BKCI 1OS2A 4IN9A 1BM6A 2USNA 1PWVA 3WV2A 3Q2GA 3KMCA 1C8TA 2OVZA 4GR0A 1CXVA 1OS9A 4G0DA 1CQRA 3F16A 4JIJA 4FXQA 1OMJA 4PKQA 1XFUA 1L6JA 2YIGA 1OM8A 1MMQA 3LQ0A 4DV8A 1HTDA 3DTEA 3K7LA 1XURA 2OXZA 1PWUA 1XUCA 2MLSA 3L0VA 1ZTQA 4GR8A 2X3CA 4QKZA 3HDAP 1CGEA 2MLRA 1Y0VA 1XFVA 4JA1A 2O3EA 1JH1A 5H8XA 4WKEA 456CA 2EROA 3GBOA 1QIBA 3KECA 5LABA 4A7BA 1OO9A 5JMYA 1GE5A 1KUIA 2WO9A 2X7MA 3EWJA 5I2ZA 5I4OA 4AYKA 5I0LA 1ZXCA 2SRTA 1QICA 4AIGA 3F15A 2RJPA 1BQOA 3E8RA 1B8YA 2V4BA 3I7GA 4H49A 1MMPA 1RM8A 1XFWA 3UVCA 1BKCA 1KUKA 1BIWA 4PKVA 3TSKA 1D8MA 1UTZA 1BUDA 1QJJA 1A86A 3DWBA 1GO8P 3EDZA 4IUWA 1USNA 1IAAA 3LQBA 1ND1A 2DDYA 5I12A 1MMRA 4XM6A 4PKUA 2POJA 1DTHA 1C7KA 3LIKA 3F18A 5CZMA 1Y93A 4DPEA 3B2ZA 3KWVC 3TT4A 1FM1A 3Q2HA 1D7XA 4H2EA 2W13A 1KUHA 4WKIA 5I43A 3O2XA 4ILWD 3LIRA 1JAPA 4JQGA 1XFXA 4H76A 1R1HA 5D1TA 1GXDA 4JPAA 1ZS0A 2RJQA 3BA0A 1PWQA 3ZXHA 1ZVXA 1R54A 3DTIA 1O0QA 2DDFA 2JNPA 1S4BP 4R3VA 1GE6A 3LUNA 1SRPA 1K7IA 3RTTA 1O0TA 4IJOA 1GE7A 3VTGA 4XBHA 1OM7A 2L0RA 1UMTA 1JIWP 2K2GA 1B3DA 1XFZA 4ON1A 1OM6A 3KRYA 2KRJA 2OI0A 3OHOA 1BSWA 1UMSA 3HBUP 1AKLA 1GKDA 1MNCA 4GF1A 3DPEA 1PWPA 1K7QA 2X3BA 2E2DA 3AIGA 3V96B 4H3XA 4A3WA 5I3MA 2MZIA 3MA2A 4DD8A 2CLTA 1BQQM 2A8HA 2O36A 4XCTA 4ZR5A 3KMEA 2W15A 2OW0A 4I03A 3HB2P 3P1VA 3LEAA 2OVXA 2MZEA 3EDHA 2OW9A 3HDBA 2OXUA 4EFSA 1JAQA 4WK7A 1GO7P 4PKRA 4PKTA 1DMTA 1QIAA 3N2UA 2QPJA 1H71P 2D1NA 5L7FA 1UTTA 1IAGA 1GKCA 3P24A 4G9LA 2Y6DA 5L79A 1C3IA 5D1UA 3HYGA 1EAKA 1CGLA 1G4KA 1SLMA 4HMAA 3DL1A 3DSLA 1HV5A 2ERQA 1UEAA 3I7IA 1CGFA 5CUHA 1IABA 3LK8A 1BZSA 5B5OA 3O64A 4JP4A 3USNA 2XS3A 3WV1A 2E3XA 1R55A 2OW1A 1YP1A 4L7AA 4I35A 1EB6A 5D1SA 1RMZA 3TVCA 4GUYA 1AF0A 1MMBA 4GWMA 3KHIA 2X3AA 1J7NA 2TCLA 3AYKA 4L63A 2XS4A 3G5CA 3LILA 2YUFA 3SHIA 966CA 2FV9A 2DW0A 1QUAA 3NX7A 4H84A 4XM8A 1D8FA 5D3CA 4FVLA 2W0DA 2WOAA 1HOVA 2Y6CA 2I47A 5D7WA 1R1IA 3LJTA 3OHLA 4L6TA 3HY7A 1I73A 2OXWA 3TS4A 1QJIA 3LE9A 4WZVA 1SATA 5BPAA 3LUMA 1CIZA 1I1IP 2OY4A 3ELMA 1BKCE 2JT5A 3AYUA 4GR3A 1IAEA 3DPFA 1KUFA 3L0TA 4H30A 4XM7A 830CA 3F1AA 2CKIA 1KAPP 1JIZA 1SMPA 4Q1LA 1CK7A 4DF9A 4FXYP 1G05A 4GQLA 1G49A 2W14A 3B92A 1IACA 3LKAA 3N2VA 1ASTA 3K7NA 1JJ9A 5B5PA 3EHYA 1YQYA 1ATLA 3VI1A 3U1RA 1EUBA 1D5JA 4J4MA 3EHXA 2DW2A 4CTHA 4PKWA 3RTSA 3HY9A 5BOYA 1JK3A 2J0TA 2YB9A 2JT6A 4PKSA 3LGPA 1IADA 2AIGP 4AXQA 4HX3A 1HFSA 1YCMA 3LJZA 1K7GA 3B8ZA 1PWWA 1Q3AA 2OY2A 1ZP5A 1HY7A 4L19A 3F19A 2N8RA 3ZUKA 4FU4A 3KEKA 1JAOA 2K9CA 5CXAA 1SLNA 3LMCA 1JANA 4GWNA 3LJGA 3G42A 1ROSA 2JSDA 2FV5A 1R1JA 4WF6A 1HFCA 1CAQA 1YOUA 1G9KA 1AYKA 2WO8A 2JIHA 3EDGA 1FBLA 3HBVP 2OZRA 2Z2DA 3ZVSA 5D2BA 2AYKA 3WV3A 1XFYA 4AUOA 2ERPA 1KBCA 3CKIA 2J83A 1I76A 1ZXVA 4H82A 1BUVM 1FLSA 1SU3A 2HU6A 2DW1A 1Z3JA 2PJTA 1WNIA 3KEJA 1G12A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A85 A;  1XUD A;  5BOT A;  2W12 A;  1KUG A;  1Y8J A;  3F17 A;  2OW2 A;  2MZH A;  3EDI A;  4H1Q A;  1JKY A;  2D1O A;  3DNG A;  1BKC I;  1OS2 A;  4IN9 A;  1BM6 A;  2USN A;  1PWV A;  3WV2 A;  3Q2G A;  3KMC A;  1C8T A;  2OVZ A;  4GR0 A;  1CXV A;  1OS9 A;  4G0D A;  1CQR A;  3F16 A;  4JIJ A;  4FXQ A;  1OMJ A;  4PKQ A;  1XFU A;  1L6J A;  2YIG A;  1OM8 A;  1MMQ A;  3LQ0 A;  4DV8 A;  1HTD A;  3K7L A;  1XUR A;  2OXZ A;  1PWU A;  1XUC A;  2MLS A;  3L0V A;  1ZTQ A;  4GR8 A;  2X3C A;  4QKZ A;  3HDA P;  1CGE A;  2MLR A;  1Y0V A;  1XFV A;  4JA1 A;  2O3E A;  1JH1 A;  5H8X A;  4WKE A;  456C A;  2ERO A;  3GBO A;  1QIB A;  3KEC A;  5LAB A;  4A7B A;  1OO9 A;  5JMY A;  1GE5 A;  1KUI A;  2WO9 A;  2X7M A;  3EWJ A;  5I2Z A;  5I4O A;  4AYK A;  5I0L A;  1ZXC A;  2SRT A;  1QIC A;  4AIG A;  3F15 A;  2RJP A;  1BQO A;  3E8R A;  1B8Y A;  2V4B A;  3I7G A;  4H49 A;  1MMP A;  1RM8 A;  1XFW A;  3UVC A;  1BKC A;  1KUK A;  1BIW A;  4PKV A;  3TSK A;  1D8M A;  1UTZ A;  1BUD A;  1QJJ A;  1A86 A;  3DWB A;  1GO8 P;  3EDZ A;  4IUW A;  1USN A;  1IAA A;  3LQB A;  1ND1 A;  2DDY A;  5I12 A;  1MMR A;  4XM6 A;  4PKU A;  2POJ A;  1DTH A;  1C7K A;  3LIK A;  3F18 A;  5CZM A;  1Y93 A;  4DPE A;  3B2Z A;  3KWV C;  3TT4 A;  1FM1 A;  3Q2H A;  1D7X A;  4H2E A;  2W13 A;  1KUH A;  4WKI A;  5I43 A;  3O2X A;  4ILW D;  3LIR A;  1JAP A;  4JQG A;  1XFX A;  4H76 A;  1R1H A;  5D1T A;  1GXD A;  4JPA A;  1ZS0 A;  2RJQ A;  3BA0 A;  1PWQ A;  3ZXH A;  1ZVX A;  1R54 A;  1O0Q A;  2DDF A;  2JNP A;  1S4B P;  4R3V A;  1GE6 A;  3LUN A;  1SRP A;  1K7I A;  3RTT A;  1O0T A;  4IJO A;  1GE7 A;  3VTG A;  4XBH A;  1OM7 A;  2L0R A;  1UMT A;  1JIW P;  2K2G A;  1B3D A;  1XFZ A;  4ON1 A;  1OM6 A;  3KRY A;  2KRJ A;  2OI0 A;  3OHO A;  1BSW A;  1UMS A;  3HBU P;  1AKL A;  1GKD A;  1MNC A;  4GF1 A;  3DPE A;  1PWP A;  1K7Q A;  2X3B A;  2E2D A;  3AIG A;  3V96 B;  4H3X A;  4A3W A;  5I3M A;  2MZI A;  3MA2 A;  4DD8 A;  2CLT A;  1BQQ M;  2A8H A;  2O36 A;  4XCT A;  4ZR5 A;  3KME A;  2W15 A;  2OW0 A;  4I03 A;  3HB2 P;  3P1V A;  3LEA A;  2OVX A;  2MZE A;  3EDH A;  2OW9 A;  3HDB A;  2OXU A;  4EFS A;  1JAQ A;  4WK7 A;  1GO7 P;  4PKR A;  4PKT A;  1DMT A;  1QIA A;  3N2U A;  2QPJ A;  1H71 P;  2D1N A;  5L7F A;  1UTT A;  1IAG A;  1GKC A;  3P24 A;  4G9L A;  2Y6D A;  5L79 A;  1C3I A;  5D1U A;  3HYG A;  1EAK A;  1CGL A;  1G4K A;  1SLM A;  4HMA A;  3DL1 A;  3DSL A;  1HV5 A;  2ERQ A;  1UEA A;  3I7I A;  1CGF A;  5CUH A;  1IAB A;  3LK8 A;  1BZS A;  5B5O A;  3O64 A;  4JP4 A;  3USN A;  2XS3 A;  3WV1 A;  2E3X A;  1R55 A;  2OW1 A;  1YP1 A;  4I35 A;  1EB6 A;  5D1S A;  1RMZ A;  3TVC A;  4GUY A;  1AF0 A;  1MMB A;  4GWM A;  3KHI A;  2X3A A;  1J7N A;  2TCL A;  3AYK A;  4L63 A;  2XS4 A;  3G5C A;  3LIL A;  3SHI A;  966C A;  2FV9 A;  2DW0 A;  1QUA A;  3NX7 A;  4H84 A;  4XM8 A;  1D8F A;  5D3C A;  4FVL A;  2W0D A;  2WOA A;  1HOV A;  2Y6C A;  2I47 A;  5D7W A;  1R1I A;  3LJT A;  3OHL A;  4L6T A;  3HY7 A;  1I73 A;  2OXW A;  3TS4 A;  1QJI A;  3LE9 A;  4WZV A;  1SAT A;  5BPA A;  3LUM A;  1CIZ A;  1I1I P;  2OY4 A;  3ELM A;  1BKC E;  2JT5 A;  3AYU A;  4GR3 A;  1IAE A;  3DPF A;  1KUF A;  3L0T A;  4H30 A;  4XM7 A;  830C A;  3F1A A;  2CKI A;  1KAP P;  1JIZ A;  1SMP A;  4Q1L A;  1CK7 A;  4DF9 A;  4FXY P;  1G05 A;  4GQL A;  1G49 A;  2W14 A;  3B92 A;  1IAC A;  3LKA A;  3N2V A;  1AST A;  3K7N A;  1JJ9 A;  5B5P A;  3EHY A;  1YQY A;  1ATL A;  3VI1 A;  3U1R A;  1EUB A;  1D5J A;  4J4M A;  3EHX A;  2DW2 A;  4CTH A;  4PKW A;  3RTS A;  3HY9 A;  5BOY A;  1JK3 A;  2J0T A;  2YB9 A;  2JT6 A;  4PKS A;  3LGP A;  1IAD A;  2AIG P;  4AXQ A;  4HX3 A;  1HFS A;  1YCM A;  3LJZ A;  1K7G A;  3B8Z A;  1PWW A;  1Q3A A;  2OY2 A;  1ZP5 A;  1HY7 A;  4L19 A;  3F19 A;  2N8R A;  3ZUK A;  4FU4 A;  3KEK A;  1JAO A;  2K9C A;  5CXA A;  1SLN A;  3LMC A;  1JAN A;  4GWN A;  3LJG A;  3G42 A;  1ROS A;  2JSD A;  2FV5 A;  1R1J A;  4WF6 A;  1HFC A;  1CAQ A;  1YOU A;  1G9K A;  1AYK A;  2WO8 A;  2JIH A;  3EDG A;  1FBL A;  3HBV P;  2OZR A;  2Z2D A;  3ZVS A;  5D2B A;  2AYK A;  3WV3 A;  1XFY A;  4AUO A;  2ERP A;  1KBC A;  3CKI A;  2J83 A;  1I76 A;  1ZXV A;  4H82 A;  1BUV M;  1FLS A;  1SU3 A;  2HU6 A;  2DW1 A;  1Z3J A;  2PJT A;  1WNI A;  3KEJ A;  1G12 A; 
#chains in the Genus database with same CATH topology
 1A85 A;  1XUD A;  5BOT A;  2W12 A;  1KUG A;  1Y8J A;  3F17 A;  2OW2 A;  2MZH A;  3DTK A;  3EDI A;  4H1Q A;  1JKY A;  2D1O A;  3DNG A;  1BKC I;  1OS2 A;  4IN9 A;  1BM6 A;  2USN A;  1PWV A;  3WV2 A;  3Q2G A;  3KMC A;  1C8T A;  2OVZ A;  4GR0 A;  1CXV A;  1OS9 A;  4G0D A;  1CQR A;  3F16 A;  4JIJ A;  4FXQ A;  1OMJ A;  4PKQ A;  1XFU A;  1L6J A;  2YIG A;  1OM8 A;  1MMQ A;  3LQ0 A;  4DV8 A;  1HTD A;  3DTE A;  3K7L A;  1XUR A;  2OXZ A;  1PWU A;  1XUC A;  2MLS A;  3L0V A;  1ZTQ A;  4GR8 A;  2X3C A;  4QKZ A;  3HDA P;  1CGE A;  2MLR A;  1Y0V A;  1XFV A;  4JA1 A;  2O3E A;  1JH1 A;  5H8X A;  4WKE A;  456C A;  2ERO A;  3GBO A;  1QIB A;  3KEC A;  5LAB A;  4A7B A;  1OO9 A;  5JMY A;  1GE5 A;  1KUI A;  2WO9 A;  2X7M A;  3EWJ A;  5I2Z A;  5I4O A;  4AYK A;  5I0L A;  1ZXC A;  2SRT A;  1QIC A;  4AIG A;  3F15 A;  2RJP A;  1BQO A;  3E8R A;  1B8Y A;  2V4B A;  3I7G A;  4H49 A;  1MMP A;  1RM8 A;  1XFW A;  3UVC A;  1BKC A;  1KUK A;  1BIW A;  4PKV A;  3TSK A;  1D8M A;  1UTZ A;  1BUD A;  1QJJ A;  1A86 A;  3DWB A;  1GO8 P;  3EDZ A;  4IUW A;  1USN A;  1IAA A;  3LQB A;  1ND1 A;  2DDY A;  5I12 A;  1MMR A;  4XM6 A;  4PKU A;  2POJ A;  1DTH A;  1C7K A;  3LIK A;  3F18 A;  5CZM A;  1Y93 A;  4DPE A;  3B2Z A;  3KWV C;  3TT4 A;  1FM1 A;  3Q2H A;  1D7X A;  4H2E A;  2W13 A;  1KUH A;  4WKI A;  5I43 A;  3O2X A;  4ILW D;  3LIR A;  1JAP A;  4JQG A;  1XFX A;  4H76 A;  1R1H A;  5D1T A;  1GXD A;  4JPA A;  1ZS0 A;  2RJQ A;  3BA0 A;  1PWQ A;  3ZXH A;  1ZVX A;  1R54 A;  3DTI A;  1O0Q A;  2DDF A;  2JNP A;  1S4B P;  4R3V A;  1GE6 A;  3LUN A;  1SRP A;  1K7I A;  3RTT A;  1O0T A;  4IJO A;  1GE7 A;  3VTG A;  4XBH A;  1OM7 A;  2L0R A;  1UMT A;  1JIW P;  2K2G A;  1B3D A;  1XFZ A;  4ON1 A;  1OM6 A;  3KRY A;  2KRJ A;  2OI0 A;  3OHO A;  1BSW A;  1UMS A;  3HBU P;  1AKL A;  1GKD A;  1MNC A;  4GF1 A;  3DPE A;  1PWP A;  1K7Q A;  2X3B A;  2E2D A;  3AIG A;  1XAX A;  3V96 B;  4H3X A;  4A3W A;  5I3M A;  2MZI A;  3MA2 A;  4DD8 A;  2CLT A;  1BQQ M;  2A8H A;  2O36 A;  4XCT A;  4ZR5 A;  3KME A;  2W15 A;  2OW0 A;  4I03 A;  3HB2 P;  3P1V A;  3LEA A;  2OVX A;  2MZE A;  3EDH A;  2OW9 A;  3HDB A;  2OXU A;  4EFS A;  1JAQ A;  4WK7 A;  1GO7 P;  4PKR A;  4PKT A;  1DMT A;  1QIA A;  3N2U A;  2QPJ A;  1H71 P;  1OZ9 A;  2D1N A;  5L7F A;  1UTT A;  1IAG A;  1GKC A;  3P24 A;  4G9L A;  2Y6D A;  5L79 A;  1C3I A;  5D1U A;  3HYG A;  1EAK A;  1CGL A;  1G4K A;  1SLM A;  4HMA A;  3DL1 A;  3DSL A;  1HV5 A;  2ERQ A;  1UEA A;  3I7I A;  1CGF A;  5CUH A;  1IAB A;  3LK8 A;  1BZS A;  5B5O A;  3O64 A;  4JP4 A;  3USN A;  2XS3 A;  3WV1 A;  2E3X A;  1R55 A;  2OW1 A;  1YP1 A;  4L7A A;  4I35 A;  1EB6 A;  5D1S A;  1RMZ A;  3TVC A;  4GUY A;  1AF0 A;  1MMB A;  4GWM A;  3KHI A;  2X3A A;  1J7N A;  2TCL A;  3AYK A;  4L63 A;  2XS4 A;  3G5C A;  3LIL A;  2YUF A;  3SHI A;  966C A;  2FV9 A;  2DW0 A;  1QUA A;  3NX7 A;  4H84 A;  4XM8 A;  1D8F A;  5D3C A;  4FVL A;  2W0D A;  2WOA A;  1HOV A;  2Y6C A;  2I47 A;  5D7W A;  1R1I A;  3LJT A;  3OHL A;  4L6T A;  3HY7 A;  1I73 A;  2OXW A;  3TS4 A;  1QJI A;  3LE9 A;  4WZV A;  1SAT A;  1XM5 A;  5BPA A;  3LUM A;  1CIZ A;  1I1I P;  2OY4 A;  3ELM A;  1BKC E;  2JT5 A;  3AYU A;  4GR3 A;  1IAE A;  3DPF A;  1KUF A;  3L0T A;  4H30 A;  4XM7 A;  830C A;  3F1A A;  2CKI A;  1KAP P;  1JIZ A;  1SMP A;  4Q1L A;  1CK7 A;  4DF9 A;  4FXY P;  1G05 A;  4GQL A;  1G49 A;  2W14 A;  3B92 A;  1IAC A;  3LKA A;  3N2V A;  1AST A;  3K7N A;  1JJ9 A;  5B5P A;  3EHY A;  1YQY A;  1ATL A;  3VI1 A;  3U1R A;  1EUB A;  1D5J A;  4J4M A;  3EHX A;  2DW2 A;  4CTH A;  4PKW A;  3RTS A;  3HY9 A;  5BOY A;  1JK3 A;  2J0T A;  2YB9 A;  2JT6 A;  4PKS A;  3LGP A;  1IAD A;  2AIG P;  4AXQ A;  4HX3 A;  1HFS A;  1YCM A;  3LJZ A;  1K7G A;  3B8Z A;  1PWW A;  1Q3A A;  2OY2 A;  1ZP5 A;  1HY7 A;  4L19 A;  3F19 A;  2N8R A;  3ZUK A;  4FU4 A;  3KEK A;  1JAO A;  2K9C A;  5CXA A;  1SLN A;  3LMC A;  1JAN A;  4GWN A;  3LJG A;  3G42 A;  1ROS A;  2JSD A;  2FV5 A;  1R1J A;  4WF6 A;  1HFC A;  1CAQ A;  1YOU A;  1G9K A;  1AYK A;  2WO8 A;  2JIH A;  3EDG A;  1FBL A;  3HBV P;  2OZR A;  1TVI A;  2Z2D A;  3ZVS A;  5D2B A;  2AYK A;  3WV3 A;  1XFY A;  4AUO A;  2ERP A;  1KBC A;  3CKI A;  2J83 A;  1I76 A;  1ZXV A;  4H82 A;  1BUV M;  1FLS A;  1SU3 A;  2HU6 A;  2DW1 A;  1Z3J A;  2PJT A;  1WNI A;  3KEJ A;  1G12 A; 
#chains in the Genus database with same CATH homology
 1A85 A;  1XUD A;  5BOT A;  2W12 A;  1KUG A;  1Y8J A;  3F17 A;  2OW2 A;  2MZH A;  3DTK A;  3EDI A;  4H1Q A;  1JKY A;  2D1O A;  3DNG A;  1BKC I;  1OS2 A;  4IN9 A;  1BM6 A;  2USN A;  1PWV A;  3WV2 A;  3Q2G A;  3KMC A;  1C8T A;  2OVZ A;  4GR0 A;  1CXV A;  1OS9 A;  4G0D A;  1CQR A;  3F16 A;  4JIJ A;  4FXQ A;  1OMJ A;  4PKQ A;  1XFU A;  1L6J A;  2YIG A;  1OM8 A;  1MMQ A;  3LQ0 A;  4DV8 A;  1HTD A;  3DTE A;  3K7L A;  1XUR A;  2OXZ A;  1PWU A;  1XUC A;  2MLS A;  3L0V A;  1ZTQ A;  4GR8 A;  2X3C A;  4QKZ A;  3HDA P;  1CGE A;  2MLR A;  1Y0V A;  1XFV A;  4JA1 A;  2O3E A;  1JH1 A;  5H8X A;  4WKE A;  456C A;  2ERO A;  3GBO A;  1QIB A;  3KEC A;  5LAB A;  4A7B A;  1OO9 A;  5JMY A;  1GE5 A;  1KUI A;  2WO9 A;  2X7M A;  3EWJ A;  5I2Z A;  5I4O A;  4AYK A;  5I0L A;  1ZXC A;  2SRT A;  1QIC A;  4AIG A;  3F15 A;  2RJP A;  1BQO A;  3E8R A;  1B8Y A;  2V4B A;  3I7G A;  4H49 A;  1MMP A;  1RM8 A;  1XFW A;  3UVC A;  1BKC A;  1KUK A;  1BIW A;  4PKV A;  3TSK A;  1D8M A;  1UTZ A;  1BUD A;  1QJJ A;  1A86 A;  3DWB A;  1GO8 P;  3EDZ A;  4IUW A;  1USN A;  1IAA A;  3LQB A;  1ND1 A;  2DDY A;  5I12 A;  1MMR A;  4XM6 A;  4PKU A;  2POJ A;  1DTH A;  1C7K A;  3LIK A;  3F18 A;  5CZM A;  1Y93 A;  4DPE A;  3B2Z A;  3KWV C;  3TT4 A;  1FM1 A;  3Q2H A;  1D7X A;  4H2E A;  2W13 A;  1KUH A;  4WKI A;  5I43 A;  3O2X A;  4ILW D;  3LIR A;  1JAP A;  4JQG A;  1XFX A;  4H76 A;  1R1H A;  5D1T A;  1GXD A;  4JPA A;  1ZS0 A;  2RJQ A;  3BA0 A;  1PWQ A;  3ZXH A;  1ZVX A;  1R54 A;  3DTI A;  1O0Q A;  2DDF A;  2JNP A;  1S4B P;  4R3V A;  1GE6 A;  3LUN A;  1SRP A;  1K7I A;  3RTT A;  1O0T A;  4IJO A;  1GE7 A;  3VTG A;  4XBH A;  1OM7 A;  2L0R A;  1UMT A;  1JIW P;  2K2G A;  1B3D A;  1XFZ A;  4ON1 A;  1OM6 A;  3KRY A;  2KRJ A;  2OI0 A;  3OHO A;  1BSW A;  1UMS A;  3HBU P;  1AKL A;  1GKD A;  1MNC A;  4GF1 A;  3DPE A;  1PWP A;  1K7Q A;  2X3B A;  2E2D A;  3AIG A;  3V96 B;  4H3X A;  4A3W A;  5I3M A;  2MZI A;  3MA2 A;  4DD8 A;  2CLT A;  1BQQ M;  2A8H A;  2O36 A;  4XCT A;  4ZR5 A;  3KME A;  2W15 A;  2OW0 A;  4I03 A;  3HB2 P;  3P1V A;  3LEA A;  2OVX A;  2MZE A;  3EDH A;  2OW9 A;  3HDB A;  2OXU A;  4EFS A;  1JAQ A;  4WK7 A;  1GO7 P;  4PKR A;  4PKT A;  1DMT A;  1QIA A;  3N2U A;  2QPJ A;  1H71 P;  2D1N A;  5L7F A;  1UTT A;  1IAG A;  1GKC A;  3P24 A;  4G9L A;  2Y6D A;  5L79 A;  1C3I A;  5D1U A;  3HYG A;  1EAK A;  1CGL A;  1G4K A;  1SLM A;  4HMA A;  3DL1 A;  3DSL A;  1HV5 A;  2ERQ A;  1UEA A;  3I7I A;  1CGF A;  5CUH A;  1IAB A;  3LK8 A;  1BZS A;  5B5O A;  3O64 A;  4JP4 A;  3USN A;  2XS3 A;  3WV1 A;  2E3X A;  1R55 A;  2OW1 A;  1YP1 A;  4L7A A;  4I35 A;  1EB6 A;  5D1S A;  1RMZ A;  3TVC A;  4GUY A;  1AF0 A;  1MMB A;  4GWM A;  3KHI A;  2X3A A;  1J7N A;  2TCL A;  3AYK A;  4L63 A;  2XS4 A;  3G5C A;  3LIL A;  2YUF A;  3SHI A;  966C A;  2FV9 A;  2DW0 A;  1QUA A;  3NX7 A;  4H84 A;  4XM8 A;  1D8F A;  5D3C A;  4FVL A;  2W0D A;  2WOA A;  1HOV A;  2Y6C A;  2I47 A;  5D7W A;  1R1I A;  3LJT A;  3OHL A;  4L6T A;  3HY7 A;  1I73 A;  2OXW A;  3TS4 A;  1QJI A;  3LE9 A;  4WZV A;  1SAT A;  5BPA A;  3LUM A;  1CIZ A;  1I1I P;  2OY4 A;  3ELM A;  1BKC E;  2JT5 A;  3AYU A;  4GR3 A;  1IAE A;  3DPF A;  1KUF A;  3L0T A;  4H30 A;  4XM7 A;  830C A;  3F1A A;  2CKI A;  1KAP P;  1JIZ A;  1SMP A;  4Q1L A;  1CK7 A;  4DF9 A;  4FXY P;  1G05 A;  4GQL A;  1G49 A;  2W14 A;  3B92 A;  1IAC A;  3LKA A;  3N2V A;  1AST A;  3K7N A;  1JJ9 A;  5B5P A;  3EHY A;  1YQY A;  1ATL A;  3VI1 A;  3U1R A;  1EUB A;  1D5J A;  4J4M A;  3EHX A;  2DW2 A;  4CTH A;  4PKW A;  3RTS A;  3HY9 A;  5BOY A;  1JK3 A;  2J0T A;  2YB9 A;  2JT6 A;  4PKS A;  3LGP A;  1IAD A;  2AIG P;  4AXQ A;  4HX3 A;  1HFS A;  1YCM A;  3LJZ A;  1K7G A;  3B8Z A;  1PWW A;  1Q3A A;  2OY2 A;  1ZP5 A;  1HY7 A;  4L19 A;  3F19 A;  2N8R A;  3ZUK A;  4FU4 A;  3KEK A;  1JAO A;  2K9C A;  5CXA A;  1SLN A;  3LMC A;  1JAN A;  4GWN A;  3LJG A;  3G42 A;  1ROS A;  2JSD A;  2FV5 A;  1R1J A;  4WF6 A;  1HFC A;  1CAQ A;  1YOU A;  1G9K A;  1AYK A;  2WO8 A;  2JIH A;  3EDG A;  1FBL A;  3HBV P;  2OZR A;  2Z2D A;  3ZVS A;  5D2B A;  2AYK A;  3WV3 A;  1XFY A;  4AUO A;  2ERP A;  1KBC A;  3CKI A;  2J83 A;  1I76 A;  1ZXV A;  4H82 A;  1BUV M;  1FLS A;  1SU3 A;  2HU6 A;  2DW1 A;  1Z3J A;  2PJT A;  1WNI A;  3KEJ A;  1G12 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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