1UTTA

Crystal structure of mmp-12 complexed to 2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)ethyl-4-(4-ethoxy[1,1-biphenyl]-4-yl)-4-oxobutanoic acid
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12.
pubmed doi rcsb
molecule keywords MACROPHAGE METALLOELASTASE
molecule tags Hydrolase
source organism Homo sapiens
total genus 44
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2003-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1uttA00
1YOUA 3LK8A 3LQ0A 1C3IA 4R3VA 2W14A 3LIRA 1EAKA 1K7GA 1I73A 2E3XA 1D8MA 2V4BA 3TSKA 2MZHA 2DW1A 4H3XA 5I0LA 1XFUA 1QUAA 4JPAA 4XM7A 5I2ZA 2JT6A 5BOYA 1YQYA 2AYKA 1JANA 3EWJA 1UMSA 2L0RA 1G05A 1IABA 1JJ9A 3WV1A 3WV3A 1PWQA 3VI1A 1SMPA 4GR3A 3LJTA 3LUMA 4PKTA 830CA 4H1QA 1BM6A 4PKRA 1BKCA 1KUHA 4IJOA 1MNCA 2DW2A 1J7NA 1KUGA 2XS3A 3LJGA 3N2UA 2X3AA 2QPJA 2MLSA 5D7WA 3KHIA 2YIGA 5D3CA 4GWMA 4A3WA 1R1JA 3NX7A 3I7GA 2D1OA 4ZR5A 1KUFA 3RTSA 1MMBA 4JQGA 2YB9A 2SRTA 3OHLA 1CGLA 1D8FA 5CXAA 4H76A 4PKUA 1C8TA 4FXQA 1FM1A 5CZMA 4J4MA 1BUDA 4IUWA 1FBLA 2OY2A 4GUYA 2N8RA 2XS4A 1OM6A 3HDAP 1HV5A 1PWWA 3E8RA 3SHIA 3TT4A 2WO8A 2Z2DA 1D7XA 1JAQA 1GE5A 2J0TA 1GE7A 1CIZA 3DSLA 5BPAA 1OM7A 4PKVA 1ZXCA 3EHYA 3B2ZA 1BQQM 1B8YA 4H82A 3Q2GA 1EB6A 2RJPA 3ZUKA 4A7BA 2ERPA 1KBCA 1GO8P 3WV2A 2JSDA 1MMQA 4GF1A 1G12A 1CQRA 1SU3A 5I3MA 4AXQA 2O3EA 3HYGA 2A8HA 4IN9A 3LILA 1GKDA 3B92A 4XCTA 3P1VA 1R55A 2X3CA 3G42A 966CA 2OXWA 4GR8A 3EHXA 4DD8A 3DPFA 1HFCA 1XFWA 3N2VA 1JH1A 3LMCA 4GWNA 5L7FA 4GQLA 1BZSA 3KMCA 3B8ZA 3HDBA 1HOVA 1CK7A 5L79A 4CTHA 4G0DA 1XFXA 1ZS0A 1SRPA 5I43A 1ZXVA 2W0DA 1Q3AA 3AYUA 2ERQA 3MA2A 1JIWP 4DV8A 4PKSA 2Y6CA 1JIZA 1UTZA 1QICA 1YCMA 5D1UA 1QIAA 3BA0A 4XBHA 4WF6A 4DF9A 2OY4A 3LIKA 2OW0A 1OS2A 2DDFA 1G4KA 3F18A 1GKCA 1A85A 1USNA 1SLNA 4H30A 1OS9A 2CLTA 2OW1A 3AYKA 5B5PA 4AUOA 1YP1A 5B5OA 1OM8A 3HBUP 1UTTA 1ASTA 3LJZA 5D1SA 3GBOA 3KEKA 3L0TA 1MMRA 1PWVA 3O64A 1IAEA 2USNA 3CKIA 4ILWD 2MZIA 4G9LA 3OHOA 1Y93A 4L6TA 1PWUA 3UVCA 1R54A 1O0TA 3ZVSA 2DW0A 3LUNA 2FV9A 1QIBA 4L19A 1O0QA 3AIGA 1KAPP 3KMEA 1ZVXA 2EROA 3DPEA 5I12A 4Q1LA 4AIGA 4PKWA 456CA 3F1AA 1XUDA 5D2BA 1KUKA 2X7MA 3LEAA 2CKIA 1EUBA 2OXZA 3K7LA 1CXVA 3KRYA 3EDHA 5H8XA 2JT5A 3O2XA 1XURA 5D1TA 3EDZA 5BOTA 2K9CA 4PKQA 1BKCE 1JK3A 1C7KA 2OZRA 1R1HA 2Y6DA 4JA1A 1H71P 5JMYA 3DWBA 4WK7A 4ON1A 1D5JA 4HMAA 1AYKA 4H49A 4DPEA 1Y8JA 4H2EA 5LABA 1DTHA 1ZTQA 3HBVP 3LKAA 2E2DA 1JAPA 1OMJA 3DL1A 1PWPA 1I1IP 1B3DA 3TVCA 3Q2HA 3F16A 2OVZA 3EDGA 1G49A 1CAQA 1CGFA 2PJTA 3L0VA 1A86A 2K2GA 4XM8A 1HY7A 3HB2P 3K7NA 1MMPA 1G9KA 2HU6A 3F15A 1SLMA 4WZVA 1JKYA 1BQOA 4JP4A 4L63A 1ND1A 2AIGP 4I03A 1RM8A 1Y0VA 4QKZA 2W13A 2KRJA 3I7IA 3F19A 1CGEA 1HFSA 2I47A 1GE6A 3TS4A 2JNPA 1L6JA 2TCLA 3KECA 1UEAA 3F17A 2W15A 1BSWA 2MLRA 2OW9A 2OVXA 2FV5A 1K7QA 1I76A 5CUHA 1ZP5A 4WKEA 1IADA 1QJJA 2OI0A 2X3BA 1OO9A 1S4BP 1XFYA 1WNIA 4EFSA 2DDYA 3EDIA 4WKIA 1FLSA 3P24A 1ATLA 3LE9A 4FVLA 1BKCI 1HTDA 1IAGA 1Z3JA 1BUVM 1QJIA 2WOAA 3ELMA 1KUIA 4FU4A 3USNA 2WO9A 3VTGA 1AF0A 2J83A 1IAAA 3RTTA 1GXDA 1XUCA 1SATA 2OW2A 2MZEA 1R1IA 2OXUA 1K7IA 1XFZA 3V96B 3KWVC 3ZXHA 4AYKA 3LGPA 1ROSA 2POJA 4H84A 4HX3A 1AKLA 1JAOA 1XFVA 3KEJA 2W12A 1GO7P 2JIHA 5I4OA 4FXYP 1UMTA 1BIWA 1IACA 3LQBA 3U1RA 1DMTA 2D1NA 4I35A 2RJQA 3HY7A 3HY9A 4GR0A 2O36A 1RMZA 3G5CA 3DNGA 4XM6A 4JIJA
chains in the Genus database with same CATH superfamily
1YOUA 3LK8A 3LQ0A 1C3IA 4R3VA 2W14A 3LIRA 1EAKA 1K7GA 1I73A 2E3XA 1D8MA 2V4BA 3TSKA 2MZHA 2DW1A 4H3XA 5I0LA 1XFUA 1QUAA 4JPAA 4XM7A 5I2ZA 2JT6A 5BOYA 3DTKA 3DTIA 1YQYA 2AYKA 1JANA 3EWJA 1UMSA 2L0RA 1G05A 1IABA 1JJ9A 3WV1A 3WV3A 1PWQA 3VI1A 1SMPA 4GR3A 3LJTA 3LUMA 4PKTA 830CA 4H1QA 1BM6A 4PKRA 1BKCA 1KUHA 4IJOA 1MNCA 2DW2A 1J7NA 1KUGA 2XS3A 3LJGA 3N2UA 2X3AA 2QPJA 2MLSA 5D7WA 3KHIA 2YIGA 5D3CA 4GWMA 4A3WA 1R1JA 3NX7A 3I7GA 2D1OA 4ZR5A 1KUFA 3RTSA 1MMBA 4JQGA 2YB9A 2SRTA 3OHLA 1CGLA 1D8FA 5CXAA 4H76A 4PKUA 1C8TA 4FXQA 1FM1A 5CZMA 4J4MA 1BUDA 4IUWA 1FBLA 2OY2A 4GUYA 2N8RA 2XS4A 1OM6A 3HDAP 1HV5A 1PWWA 3E8RA 3SHIA 3TT4A 1XM5A 2WO8A 2Z2DA 1D7XA 1JAQA 1GE5A 2J0TA 1GE7A 1CIZA 3DSLA 5BPAA 1OM7A 4PKVA 1ZXCA 3EHYA 3B2ZA 1BQQM 1B8YA 4H82A 3Q2GA 1EB6A 2RJPA 3ZUKA 4A7BA 2ERPA 1KBCA 1GO8P 3WV2A 2JSDA 1MMQA 4GF1A 1G12A 1CQRA 1SU3A 5I3MA 4AXQA 2O3EA 3HYGA 2A8HA 4IN9A 3LILA 1GKDA 3B92A 4XCTA 3P1VA 1R55A 2X3CA 3G42A 966CA 2OXWA 4GR8A 3EHXA 4DD8A 3DPFA 1HFCA 1XFWA 3N2VA 1JH1A 3LMCA 4GWNA 5L7FA 4GQLA 1BZSA 3KMCA 3B8ZA 3HDBA 1HOVA 1CK7A 5L79A 4CTHA 4G0DA 1XFXA 1ZS0A 1SRPA 5I43A 1ZXVA 2W0DA 1Q3AA 3AYUA 2ERQA 3MA2A 1JIWP 4DV8A 4PKSA 2Y6CA 1JIZA 1UTZA 1QICA 1YCMA 5D1UA 1QIAA 3BA0A 4XBHA 4WF6A 4DF9A 2OY4A 3LIKA 2OW0A 1OS2A 2DDFA 1G4KA 3F18A 1GKCA 1A85A 1USNA 1SLNA 4H30A 1OS9A 2CLTA 2OW1A 3AYKA 5B5PA 4AUOA 1YP1A 5B5OA 1OM8A 3HBUP 1UTTA 1ASTA 3LJZA 5D1SA 3GBOA 3KEKA 3L0TA 1MMRA 1PWVA 3O64A 1IAEA 2USNA 3CKIA 4ILWD 2MZIA 4G9LA 3OHOA 4L7AA 1Y93A 4L6TA 1PWUA 1TVIA 3UVCA 1R54A 1O0TA 3ZVSA 2DW0A 3LUNA 2FV9A 1QIBA 4L19A 1O0QA 3AIGA 1KAPP 3KMEA 1ZVXA 2EROA 3DPEA 5I12A 4Q1LA 4AIGA 4PKWA 456CA 3F1AA 1XUDA 5D2BA 1KUKA 2X7MA 3DTEA 3LEAA 2CKIA 1EUBA 2OXZA 3K7LA 1CXVA 3KRYA 3EDHA 5H8XA 2JT5A 3O2XA 1XURA 5D1TA 3EDZA 5BOTA 2K9CA 4PKQA 1BKCE 1JK3A 1C7KA 2OZRA 1R1HA 2Y6DA 4JA1A 1H71P 5JMYA 3DWBA 4WK7A 4ON1A 1D5JA 2YUFA 4HMAA 1AYKA 4H49A 4DPEA 1Y8JA 4H2EA 5LABA 1DTHA 1ZTQA 3HBVP 3LKAA 2E2DA 1JAPA 1OMJA 3DL1A 1PWPA 1I1IP 1B3DA 3TVCA 3Q2HA 3F16A 2OVZA 3EDGA 1G49A 1CAQA 1CGFA 2PJTA 3L0VA 1A86A 2K2GA 4XM8A 1HY7A 3HB2P 3K7NA 1MMPA 1G9KA 2HU6A 3F15A 1SLMA 4WZVA 1JKYA 1BQOA 4JP4A 4L63A 1ND1A 2AIGP 4I03A 1RM8A 1Y0VA 4QKZA 2W13A 2KRJA 3I7IA 3F19A 1CGEA 1HFSA 2I47A 1GE6A 3TS4A 2JNPA 1L6JA 2TCLA 3KECA 1UEAA 3F17A 2W15A 1BSWA 2MLRA 2OW9A 2OVXA 2FV5A 1K7QA 1I76A 5CUHA 1ZP5A 4WKEA 1IADA 1QJJA 2OI0A 2X3BA 1OO9A 1S4BP 1XFYA 1WNIA 4EFSA 2DDYA 3EDIA 4WKIA 1FLSA 3P24A 1ATLA 3LE9A 4FVLA 1BKCI 1HTDA 1IAGA 1Z3JA 1BUVM 1QJIA 2WOAA 3ELMA 1KUIA 4FU4A 3USNA 2WO9A 3VTGA 1AF0A 2J83A 1IAAA 3RTTA 1GXDA 1XUCA 1SATA 2OW2A 2MZEA 1R1IA 2OXUA 1K7IA 1XFZA 3V96B 1OZ9A 3KWVC 3ZXHA 4AYKA 3LGPA 1ROSA 2POJA 4H84A 4HX3A 1AKLA 1JAOA 1XFVA 3KEJA 2W12A 1GO7P 2JIHA 5I4OA 4FXYP 1UMTA 1BIWA 1IACA 3LQBA 3U1RA 1DMTA 2D1NA 4I35A 2RJQA 3HY7A 3HY9A 4GR0A 2O36A 1RMZA 3G5CA 3DNGA 4XM6A 1XAXA 4JIJA
chains in the Genus database with same CATH topology
1YOUA 3LK8A 3LQ0A 1C3IA 4R3VA 2W14A 3LIRA 1EAKA 1K7GA 1I73A 2E3XA 1D8MA 2V4BA 3TSKA 2MZHA 2DW1A 4H3XA 5I0LA 1XFUA 1QUAA 4JPAA 4XM7A 5I2ZA 2JT6A 5BOYA 3DTKA 3DTIA 1YQYA 2AYKA 1JANA 3EWJA 1UMSA 2L0RA 1G05A 1IABA 1JJ9A 3WV1A 3WV3A 1PWQA 3VI1A 1SMPA 4GR3A 3LJTA 3LUMA 4PKTA 830CA 4H1QA 1BM6A 4PKRA 1BKCA 1KUHA 4IJOA 1MNCA 2DW2A 1J7NA 1KUGA 2XS3A 3LJGA 3N2UA 2X3AA 2QPJA 2MLSA 5D7WA 3KHIA 2YIGA 5D3CA 4GWMA 4A3WA 1R1JA 3NX7A 3I7GA 2D1OA 4ZR5A 1KUFA 3RTSA 1MMBA 4JQGA 2YB9A 2SRTA 3OHLA 1CGLA 1D8FA 5CXAA 4H76A 4PKUA 1C8TA 4FXQA 1FM1A 5CZMA 4J4MA 1BUDA 4IUWA 1FBLA 2OY2A 4GUYA 2N8RA 2XS4A 1OM6A 3HDAP 1HV5A 1PWWA 3E8RA 3SHIA 3TT4A 2WO8A 2Z2DA 1D7XA 1JAQA 1GE5A 2J0TA 1GE7A 1CIZA 3DSLA 5BPAA 1OM7A 4PKVA 1ZXCA 3EHYA 3B2ZA 1BQQM 1B8YA 4H82A 3Q2GA 1EB6A 2RJPA 3ZUKA 4A7BA 2ERPA 1KBCA 1GO8P 3WV2A 2JSDA 1MMQA 4GF1A 1G12A 1CQRA 1SU3A 5I3MA 4AXQA 2O3EA 3HYGA 2A8HA 4IN9A 3LILA 1GKDA 3B92A 4XCTA 3P1VA 1R55A 2X3CA 3G42A 966CA 2OXWA 4GR8A 3EHXA 4DD8A 3DPFA 1HFCA 1XFWA 3N2VA 1JH1A 3LMCA 4GWNA 5L7FA 4GQLA 1BZSA 3KMCA 3B8ZA 3HDBA 1HOVA 1CK7A 5L79A 4CTHA 4G0DA 1XFXA 1ZS0A 1SRPA 5I43A 1ZXVA 2W0DA 1Q3AA 3AYUA 2ERQA 3MA2A 1JIWP 4DV8A 4PKSA 2Y6CA 1JIZA 1UTZA 1QICA 1YCMA 5D1UA 1QIAA 3BA0A 4XBHA 4WF6A 4DF9A 2OY4A 3LIKA 2OW0A 1OS2A 2DDFA 1G4KA 3F18A 1GKCA 1A85A 1USNA 1SLNA 4H30A 1OS9A 2CLTA 2OW1A 3AYKA 5B5PA 4AUOA 1YP1A 5B5OA 1OM8A 3HBUP 1UTTA 1ASTA 3LJZA 5D1SA 3GBOA 3KEKA 3L0TA 1MMRA 1PWVA 3O64A 1IAEA 2USNA 3CKIA 4ILWD 2MZIA 4G9LA 3OHOA 4L7AA 1Y93A 4L6TA 1PWUA 3UVCA 1R54A 1O0TA 3ZVSA 2DW0A 3LUNA 2FV9A 1QIBA 4L19A 1O0QA 3AIGA 1KAPP 3KMEA 1ZVXA 2EROA 3DPEA 5I12A 4Q1LA 4AIGA 4PKWA 456CA 3F1AA 1XUDA 5D2BA 1KUKA 2X7MA 3DTEA 3LEAA 2CKIA 1EUBA 2OXZA 3K7LA 1CXVA 3KRYA 3EDHA 5H8XA 2JT5A 3O2XA 1XURA 5D1TA 3EDZA 5BOTA 2K9CA 4PKQA 1BKCE 1JK3A 1C7KA 2OZRA 1R1HA 2Y6DA 4JA1A 1H71P 5JMYA 3DWBA 4WK7A 4ON1A 1D5JA 2YUFA 4HMAA 1AYKA 4H49A 4DPEA 1Y8JA 4H2EA 5LABA 1DTHA 1ZTQA 3HBVP 3LKAA 2E2DA 1JAPA 1OMJA 3DL1A 1PWPA 1I1IP 1B3DA 3TVCA 3Q2HA 3F16A 2OVZA 3EDGA 1G49A 1CAQA 1CGFA 2PJTA 3L0VA 1A86A 2K2GA 4XM8A 1HY7A 3HB2P 3K7NA 1MMPA 1G9KA 2HU6A 3F15A 1SLMA 4WZVA 1JKYA 1BQOA 4JP4A 4L63A 1ND1A 2AIGP 4I03A 1RM8A 1Y0VA 4QKZA 2W13A 2KRJA 3I7IA 3F19A 1CGEA 1HFSA 2I47A 1GE6A 3TS4A 2JNPA 1L6JA 2TCLA 3KECA 1UEAA 3F17A 2W15A 1BSWA 2MLRA 2OW9A 2OVXA 2FV5A 1K7QA 1I76A 5CUHA 1ZP5A 4WKEA 1IADA 1QJJA 2OI0A 2X3BA 1OO9A 1S4BP 1XFYA 1WNIA 4EFSA 2DDYA 3EDIA 4WKIA 1FLSA 3P24A 1ATLA 3LE9A 4FVLA 1BKCI 1HTDA 1IAGA 1Z3JA 1BUVM 1QJIA 2WOAA 3ELMA 1KUIA 4FU4A 3USNA 2WO9A 3VTGA 1AF0A 2J83A 1IAAA 3RTTA 1GXDA 1XUCA 1SATA 2OW2A 2MZEA 1R1IA 2OXUA 1K7IA 1XFZA 3V96B 3KWVC 3ZXHA 4AYKA 3LGPA 1ROSA 2POJA 4H84A 4HX3A 1AKLA 1JAOA 1XFVA 3KEJA 2W12A 1GO7P 2JIHA 5I4OA 4FXYP 1UMTA 1BIWA 1IACA 3LQBA 3U1RA 1DMTA 2D1NA 4I35A 2RJQA 3HY7A 3HY9A 4GR0A 2O36A 1RMZA 3G5CA 3DNGA 4XM6A 4JIJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YOU A;  3LK8 A;  3LQ0 A;  1C3I A;  4R3V A;  2W14 A;  3LIR A;  1EAK A;  1K7G A;  1I73 A;  2E3X A;  1D8M A;  2V4B A;  3TSK A;  2MZH A;  2DW1 A;  4H3X A;  5I0L A;  1XFU A;  1QUA A;  4JPA A;  4XM7 A;  5I2Z A;  2JT6 A;  5BOY A;  1YQY A;  2AYK A;  1JAN A;  3EWJ A;  1UMS A;  2L0R A;  1G05 A;  1IAB A;  1JJ9 A;  3WV1 A;  3WV3 A;  1PWQ A;  3VI1 A;  1SMP A;  4GR3 A;  3LJT A;  3LUM A;  4PKT A;  830C A;  4H1Q A;  1BM6 A;  4PKR A;  1BKC A;  1KUH A;  4IJO A;  1MNC A;  2DW2 A;  1J7N A;  1KUG A;  2XS3 A;  3LJG A;  3N2U A;  2X3A A;  2QPJ A;  2MLS A;  5D7W A;  3KHI A;  2YIG A;  5D3C A;  4GWM A;  4A3W A;  1R1J A;  3NX7 A;  3I7G A;  2D1O A;  4ZR5 A;  1KUF A;  3RTS A;  1MMB A;  4JQG A;  2YB9 A;  2SRT A;  3OHL A;  1CGL A;  1D8F A;  5CXA A;  4H76 A;  4PKU A;  1C8T A;  4FXQ A;  1FM1 A;  5CZM A;  4J4M A;  1BUD A;  4IUW A;  1FBL A;  2OY2 A;  4GUY A;  2N8R A;  2XS4 A;  1OM6 A;  3HDA P;  1HV5 A;  1PWW A;  3E8R A;  3SHI A;  3TT4 A;  2WO8 A;  2Z2D A;  1D7X A;  1JAQ A;  1GE5 A;  2J0T A;  1GE7 A;  1CIZ A;  3DSL A;  5BPA A;  1OM7 A;  4PKV A;  1ZXC A;  3EHY A;  3B2Z A;  1BQQ M;  1B8Y A;  4H82 A;  3Q2G A;  1EB6 A;  2RJP A;  3ZUK A;  4A7B A;  2ERP A;  1KBC A;  1GO8 P;  3WV2 A;  2JSD A;  1MMQ A;  4GF1 A;  1G12 A;  1CQR A;  1SU3 A;  5I3M A;  4AXQ A;  2O3E A;  3HYG A;  2A8H A;  4IN9 A;  3LIL A;  1GKD A;  3B92 A;  4XCT A;  3P1V A;  1R55 A;  2X3C A;  3G42 A;  966C A;  2OXW A;  4GR8 A;  3EHX A;  4DD8 A;  3DPF A;  1HFC A;  1XFW A;  3N2V A;  1JH1 A;  3LMC A;  4GWN A;  5L7F A;  4GQL A;  1BZS A;  3KMC A;  3B8Z A;  3HDB A;  1HOV A;  1CK7 A;  5L79 A;  4CTH A;  4G0D A;  1XFX A;  1ZS0 A;  1SRP A;  5I43 A;  1ZXV A;  2W0D A;  1Q3A A;  3AYU A;  2ERQ A;  3MA2 A;  1JIW P;  4DV8 A;  4PKS A;  2Y6C A;  1JIZ A;  1UTZ A;  1QIC A;  1YCM A;  5D1U A;  1QIA A;  3BA0 A;  4XBH A;  4WF6 A;  4DF9 A;  2OY4 A;  3LIK A;  2OW0 A;  1OS2 A;  2DDF A;  1G4K A;  3F18 A;  1GKC A;  1A85 A;  1USN A;  1SLN A;  4H30 A;  1OS9 A;  2CLT A;  2OW1 A;  3AYK A;  5B5P A;  4AUO A;  1YP1 A;  5B5O A;  1OM8 A;  3HBU P;  1UTT A;  1AST A;  3LJZ A;  5D1S A;  3GBO A;  3KEK A;  3L0T A;  1MMR A;  1PWV A;  3O64 A;  1IAE A;  2USN A;  3CKI A;  4ILW D;  2MZI A;  4G9L A;  3OHO A;  1Y93 A;  4L6T A;  1PWU A;  3UVC A;  1R54 A;  1O0T A;  3ZVS A;  2DW0 A;  3LUN A;  2FV9 A;  1QIB A;  4L19 A;  1O0Q A;  3AIG A;  1KAP P;  3KME A;  1ZVX A;  2ERO A;  3DPE A;  5I12 A;  4Q1L A;  4AIG A;  4PKW A;  456C A;  3F1A A;  1XUD A;  5D2B A;  1KUK A;  2X7M A;  3LEA A;  2CKI A;  1EUB A;  2OXZ A;  3K7L A;  1CXV A;  3KRY A;  3EDH A;  5H8X A;  2JT5 A;  3O2X A;  1XUR A;  5D1T A;  3EDZ A;  5BOT A;  2K9C A;  4PKQ A;  1BKC E;  1JK3 A;  1C7K A;  2OZR A;  1R1H A;  2Y6D A;  4JA1 A;  1H71 P;  5JMY A;  3DWB A;  4WK7 A;  4ON1 A;  1D5J A;  4HMA A;  1AYK A;  4H49 A;  4DPE A;  1Y8J A;  4H2E A;  5LAB A;  1DTH A;  1ZTQ A;  3HBV P;  3LKA A;  2E2D A;  1JAP A;  1OMJ A;  3DL1 A;  1PWP A;  1I1I P;  1B3D A;  3TVC A;  3Q2H A;  3F16 A;  2OVZ A;  3EDG A;  1G49 A;  1CAQ A;  1CGF A;  2PJT A;  3L0V A;  1A86 A;  2K2G A;  4XM8 A;  1HY7 A;  3HB2 P;  3K7N A;  1MMP A;  1G9K A;  2HU6 A;  3F15 A;  1SLM A;  4WZV A;  1JKY A;  1BQO A;  4JP4 A;  4L63 A;  1ND1 A;  2AIG P;  4I03 A;  1RM8 A;  1Y0V A;  4QKZ A;  2W13 A;  2KRJ A;  3I7I A;  3F19 A;  1CGE A;  1HFS A;  2I47 A;  1GE6 A;  3TS4 A;  2JNP A;  1L6J A;  2TCL A;  3KEC A;  1UEA A;  3F17 A;  2W15 A;  1BSW A;  2MLR A;  2OW9 A;  2OVX A;  2FV5 A;  1K7Q A;  1I76 A;  5CUH A;  1ZP5 A;  4WKE A;  1IAD A;  1QJJ A;  2OI0 A;  2X3B A;  1OO9 A;  1S4B P;  1XFY A;  1WNI A;  4EFS A;  2DDY A;  3EDI A;  4WKI A;  1FLS A;  3P24 A;  1ATL A;  3LE9 A;  4FVL A;  1BKC I;  1HTD A;  1IAG A;  1Z3J A;  1BUV M;  1QJI A;  2WOA A;  3ELM A;  1KUI A;  4FU4 A;  3USN A;  2WO9 A;  3VTG A;  1AF0 A;  2J83 A;  1IAA A;  3RTT A;  1GXD A;  1XUC A;  1SAT A;  2OW2 A;  2MZE A;  1R1I A;  2OXU A;  1K7I A;  1XFZ A;  3V96 B;  3KWV C;  3ZXH A;  4AYK A;  3LGP A;  1ROS A;  2POJ A;  4H84 A;  4HX3 A;  1AKL A;  1JAO A;  1XFV A;  3KEJ A;  2W12 A;  1GO7 P;  2JIH A;  5I4O A;  4FXY P;  1UMT A;  1BIW A;  1IAC A;  3LQB A;  3U1R A;  1DMT A;  2D1N A;  4I35 A;  2RJQ A;  3HY7 A;  3HY9 A;  4GR0 A;  2O36 A;  1RMZ A;  3G5C A;  3DNG A;  4XM6 A;  4JIJ A; 
#chains in the Genus database with same CATH topology
 1YOU A;  3LK8 A;  3LQ0 A;  1C3I A;  4R3V A;  2W14 A;  3LIR A;  1EAK A;  1K7G A;  1I73 A;  2E3X A;  1D8M A;  2V4B A;  3TSK A;  2MZH A;  2DW1 A;  4H3X A;  5I0L A;  1XFU A;  1QUA A;  4JPA A;  4XM7 A;  5I2Z A;  2JT6 A;  5BOY A;  3DTK A;  3DTI A;  1YQY A;  2AYK A;  1JAN A;  3EWJ A;  1UMS A;  2L0R A;  1G05 A;  1IAB A;  1JJ9 A;  3WV1 A;  3WV3 A;  1PWQ A;  3VI1 A;  1SMP A;  4GR3 A;  3LJT A;  3LUM A;  4PKT A;  830C A;  4H1Q A;  1BM6 A;  4PKR A;  1BKC A;  1KUH A;  4IJO A;  1MNC A;  2DW2 A;  1J7N A;  1KUG A;  2XS3 A;  3LJG A;  3N2U A;  2X3A A;  2QPJ A;  2MLS A;  5D7W A;  3KHI A;  2YIG A;  5D3C A;  4GWM A;  4A3W A;  1R1J A;  3NX7 A;  3I7G A;  2D1O A;  4ZR5 A;  1KUF A;  3RTS A;  1MMB A;  4JQG A;  2YB9 A;  2SRT A;  3OHL A;  1CGL A;  1D8F A;  5CXA A;  4H76 A;  4PKU A;  1C8T A;  4FXQ A;  1FM1 A;  5CZM A;  4J4M A;  1BUD A;  4IUW A;  1FBL A;  2OY2 A;  4GUY A;  2N8R A;  2XS4 A;  1OM6 A;  3HDA P;  1HV5 A;  1PWW A;  3E8R A;  3SHI A;  3TT4 A;  1XM5 A;  2WO8 A;  2Z2D A;  1D7X A;  1JAQ A;  1GE5 A;  2J0T A;  1GE7 A;  1CIZ A;  3DSL A;  5BPA A;  1OM7 A;  4PKV A;  1ZXC A;  3EHY A;  3B2Z A;  1BQQ M;  1B8Y A;  4H82 A;  3Q2G A;  1EB6 A;  2RJP A;  3ZUK A;  4A7B A;  2ERP A;  1KBC A;  1GO8 P;  3WV2 A;  2JSD A;  1MMQ A;  4GF1 A;  1G12 A;  1CQR A;  1SU3 A;  5I3M A;  4AXQ A;  2O3E A;  3HYG A;  2A8H A;  4IN9 A;  3LIL A;  1GKD A;  3B92 A;  4XCT A;  3P1V A;  1R55 A;  2X3C A;  3G42 A;  966C A;  2OXW A;  4GR8 A;  3EHX A;  4DD8 A;  3DPF A;  1HFC A;  1XFW A;  3N2V A;  1JH1 A;  3LMC A;  4GWN A;  5L7F A;  4GQL A;  1BZS A;  3KMC A;  3B8Z A;  3HDB A;  1HOV A;  1CK7 A;  5L79 A;  4CTH A;  4G0D A;  1XFX A;  1ZS0 A;  1SRP A;  5I43 A;  1ZXV A;  2W0D A;  1Q3A A;  3AYU A;  2ERQ A;  3MA2 A;  1JIW P;  4DV8 A;  4PKS A;  2Y6C A;  1JIZ A;  1UTZ A;  1QIC A;  1YCM A;  5D1U A;  1QIA A;  3BA0 A;  4XBH A;  4WF6 A;  4DF9 A;  2OY4 A;  3LIK A;  2OW0 A;  1OS2 A;  2DDF A;  1G4K A;  3F18 A;  1GKC A;  1A85 A;  1USN A;  1SLN A;  4H30 A;  1OS9 A;  2CLT A;  2OW1 A;  3AYK A;  5B5P A;  4AUO A;  1YP1 A;  5B5O A;  1OM8 A;  3HBU P;  1UTT A;  1AST A;  3LJZ A;  5D1S A;  3GBO A;  3KEK A;  3L0T A;  1MMR A;  1PWV A;  3O64 A;  1IAE A;  2USN A;  3CKI A;  4ILW D;  2MZI A;  4G9L A;  3OHO A;  4L7A A;  1Y93 A;  4L6T A;  1PWU A;  1TVI A;  3UVC A;  1R54 A;  1O0T A;  3ZVS A;  2DW0 A;  3LUN A;  2FV9 A;  1QIB A;  4L19 A;  1O0Q A;  3AIG A;  1KAP P;  3KME A;  1ZVX A;  2ERO A;  3DPE A;  5I12 A;  4Q1L A;  4AIG A;  4PKW A;  456C A;  3F1A A;  1XUD A;  5D2B A;  1KUK A;  2X7M A;  3DTE A;  3LEA A;  2CKI A;  1EUB A;  2OXZ A;  3K7L A;  1CXV A;  3KRY A;  3EDH A;  5H8X A;  2JT5 A;  3O2X A;  1XUR A;  5D1T A;  3EDZ A;  5BOT A;  2K9C A;  4PKQ A;  1BKC E;  1JK3 A;  1C7K A;  2OZR A;  1R1H A;  2Y6D A;  4JA1 A;  1H71 P;  5JMY A;  3DWB A;  4WK7 A;  4ON1 A;  1D5J A;  2YUF A;  4HMA A;  1AYK A;  4H49 A;  4DPE A;  1Y8J A;  4H2E A;  5LAB A;  1DTH A;  1ZTQ A;  3HBV P;  3LKA A;  2E2D A;  1JAP A;  1OMJ A;  3DL1 A;  1PWP A;  1I1I P;  1B3D A;  3TVC A;  3Q2H A;  3F16 A;  2OVZ A;  3EDG A;  1G49 A;  1CAQ A;  1CGF A;  2PJT A;  3L0V A;  1A86 A;  2K2G A;  4XM8 A;  1HY7 A;  3HB2 P;  3K7N A;  1MMP A;  1G9K A;  2HU6 A;  3F15 A;  1SLM A;  4WZV A;  1JKY A;  1BQO A;  4JP4 A;  4L63 A;  1ND1 A;  2AIG P;  4I03 A;  1RM8 A;  1Y0V A;  4QKZ A;  2W13 A;  2KRJ A;  3I7I A;  3F19 A;  1CGE A;  1HFS A;  2I47 A;  1GE6 A;  3TS4 A;  2JNP A;  1L6J A;  2TCL A;  3KEC A;  1UEA A;  3F17 A;  2W15 A;  1BSW A;  2MLR A;  2OW9 A;  2OVX A;  2FV5 A;  1K7Q A;  1I76 A;  5CUH A;  1ZP5 A;  4WKE A;  1IAD A;  1QJJ A;  2OI0 A;  2X3B A;  1OO9 A;  1S4B P;  1XFY A;  1WNI A;  4EFS A;  2DDY A;  3EDI A;  4WKI A;  1FLS A;  3P24 A;  1ATL A;  3LE9 A;  4FVL A;  1BKC I;  1HTD A;  1IAG A;  1Z3J A;  1BUV M;  1QJI A;  2WOA A;  3ELM A;  1KUI A;  4FU4 A;  3USN A;  2WO9 A;  3VTG A;  1AF0 A;  2J83 A;  1IAA A;  3RTT A;  1GXD A;  1XUC A;  1SAT A;  2OW2 A;  2MZE A;  1R1I A;  2OXU A;  1K7I A;  1XFZ A;  3V96 B;  1OZ9 A;  3KWV C;  3ZXH A;  4AYK A;  3LGP A;  1ROS A;  2POJ A;  4H84 A;  4HX3 A;  1AKL A;  1JAO A;  1XFV A;  3KEJ A;  2W12 A;  1GO7 P;  2JIH A;  5I4O A;  4FXY P;  1UMT A;  1BIW A;  1IAC A;  3LQB A;  3U1R A;  1DMT A;  2D1N A;  4I35 A;  2RJQ A;  3HY7 A;  3HY9 A;  4GR0 A;  2O36 A;  1RMZ A;  3G5C A;  3DNG A;  4XM6 A;  1XAX A;  4JIJ A; 
#chains in the Genus database with same CATH homology
 1YOU A;  3LK8 A;  3LQ0 A;  1C3I A;  4R3V A;  2W14 A;  3LIR A;  1EAK A;  1K7G A;  1I73 A;  2E3X A;  1D8M A;  2V4B A;  3TSK A;  2MZH A;  2DW1 A;  4H3X A;  5I0L A;  1XFU A;  1QUA A;  4JPA A;  4XM7 A;  5I2Z A;  2JT6 A;  5BOY A;  3DTK A;  3DTI A;  1YQY A;  2AYK A;  1JAN A;  3EWJ A;  1UMS A;  2L0R A;  1G05 A;  1IAB A;  1JJ9 A;  3WV1 A;  3WV3 A;  1PWQ A;  3VI1 A;  1SMP A;  4GR3 A;  3LJT A;  3LUM A;  4PKT A;  830C A;  4H1Q A;  1BM6 A;  4PKR A;  1BKC A;  1KUH A;  4IJO A;  1MNC A;  2DW2 A;  1J7N A;  1KUG A;  2XS3 A;  3LJG A;  3N2U A;  2X3A A;  2QPJ A;  2MLS A;  5D7W A;  3KHI A;  2YIG A;  5D3C A;  4GWM A;  4A3W A;  1R1J A;  3NX7 A;  3I7G A;  2D1O A;  4ZR5 A;  1KUF A;  3RTS A;  1MMB A;  4JQG A;  2YB9 A;  2SRT A;  3OHL A;  1CGL A;  1D8F A;  5CXA A;  4H76 A;  4PKU A;  1C8T A;  4FXQ A;  1FM1 A;  5CZM A;  4J4M A;  1BUD A;  4IUW A;  1FBL A;  2OY2 A;  4GUY A;  2N8R A;  2XS4 A;  1OM6 A;  3HDA P;  1HV5 A;  1PWW A;  3E8R A;  3SHI A;  3TT4 A;  2WO8 A;  2Z2D A;  1D7X A;  1JAQ A;  1GE5 A;  2J0T A;  1GE7 A;  1CIZ A;  3DSL A;  5BPA A;  1OM7 A;  4PKV A;  1ZXC A;  3EHY A;  3B2Z A;  1BQQ M;  1B8Y A;  4H82 A;  3Q2G A;  1EB6 A;  2RJP A;  3ZUK A;  4A7B A;  2ERP A;  1KBC A;  1GO8 P;  3WV2 A;  2JSD A;  1MMQ A;  4GF1 A;  1G12 A;  1CQR A;  1SU3 A;  5I3M A;  4AXQ A;  2O3E A;  3HYG A;  2A8H A;  4IN9 A;  3LIL A;  1GKD A;  3B92 A;  4XCT A;  3P1V A;  1R55 A;  2X3C A;  3G42 A;  966C A;  2OXW A;  4GR8 A;  3EHX A;  4DD8 A;  3DPF A;  1HFC A;  1XFW A;  3N2V A;  1JH1 A;  3LMC A;  4GWN A;  5L7F A;  4GQL A;  1BZS A;  3KMC A;  3B8Z A;  3HDB A;  1HOV A;  1CK7 A;  5L79 A;  4CTH A;  4G0D A;  1XFX A;  1ZS0 A;  1SRP A;  5I43 A;  1ZXV A;  2W0D A;  1Q3A A;  3AYU A;  2ERQ A;  3MA2 A;  1JIW P;  4DV8 A;  4PKS A;  2Y6C A;  1JIZ A;  1UTZ A;  1QIC A;  1YCM A;  5D1U A;  1QIA A;  3BA0 A;  4XBH A;  4WF6 A;  4DF9 A;  2OY4 A;  3LIK A;  2OW0 A;  1OS2 A;  2DDF A;  1G4K A;  3F18 A;  1GKC A;  1A85 A;  1USN A;  1SLN A;  4H30 A;  1OS9 A;  2CLT A;  2OW1 A;  3AYK A;  5B5P A;  4AUO A;  1YP1 A;  5B5O A;  1OM8 A;  3HBU P;  1UTT A;  1AST A;  3LJZ A;  5D1S A;  3GBO A;  3KEK A;  3L0T A;  1MMR A;  1PWV A;  3O64 A;  1IAE A;  2USN A;  3CKI A;  4ILW D;  2MZI A;  4G9L A;  3OHO A;  4L7A A;  1Y93 A;  4L6T A;  1PWU A;  3UVC A;  1R54 A;  1O0T A;  3ZVS A;  2DW0 A;  3LUN A;  2FV9 A;  1QIB A;  4L19 A;  1O0Q A;  3AIG A;  1KAP P;  3KME A;  1ZVX A;  2ERO A;  3DPE A;  5I12 A;  4Q1L A;  4AIG A;  4PKW A;  456C A;  3F1A A;  1XUD A;  5D2B A;  1KUK A;  2X7M A;  3DTE A;  3LEA A;  2CKI A;  1EUB A;  2OXZ A;  3K7L A;  1CXV A;  3KRY A;  3EDH A;  5H8X A;  2JT5 A;  3O2X A;  1XUR A;  5D1T A;  3EDZ A;  5BOT A;  2K9C A;  4PKQ A;  1BKC E;  1JK3 A;  1C7K A;  2OZR A;  1R1H A;  2Y6D A;  4JA1 A;  1H71 P;  5JMY A;  3DWB A;  4WK7 A;  4ON1 A;  1D5J A;  2YUF A;  4HMA A;  1AYK A;  4H49 A;  4DPE A;  1Y8J A;  4H2E A;  5LAB A;  1DTH A;  1ZTQ A;  3HBV P;  3LKA A;  2E2D A;  1JAP A;  1OMJ A;  3DL1 A;  1PWP A;  1I1I P;  1B3D A;  3TVC A;  3Q2H A;  3F16 A;  2OVZ A;  3EDG A;  1G49 A;  1CAQ A;  1CGF A;  2PJT A;  3L0V A;  1A86 A;  2K2G A;  4XM8 A;  1HY7 A;  3HB2 P;  3K7N A;  1MMP A;  1G9K A;  2HU6 A;  3F15 A;  1SLM A;  4WZV A;  1JKY A;  1BQO A;  4JP4 A;  4L63 A;  1ND1 A;  2AIG P;  4I03 A;  1RM8 A;  1Y0V A;  4QKZ A;  2W13 A;  2KRJ A;  3I7I A;  3F19 A;  1CGE A;  1HFS A;  2I47 A;  1GE6 A;  3TS4 A;  2JNP A;  1L6J A;  2TCL A;  3KEC A;  1UEA A;  3F17 A;  2W15 A;  1BSW A;  2MLR A;  2OW9 A;  2OVX A;  2FV5 A;  1K7Q A;  1I76 A;  5CUH A;  1ZP5 A;  4WKE A;  1IAD A;  1QJJ A;  2OI0 A;  2X3B A;  1OO9 A;  1S4B P;  1XFY A;  1WNI A;  4EFS A;  2DDY A;  3EDI A;  4WKI A;  1FLS A;  3P24 A;  1ATL A;  3LE9 A;  4FVL A;  1BKC I;  1HTD A;  1IAG A;  1Z3J A;  1BUV M;  1QJI A;  2WOA A;  3ELM A;  1KUI A;  4FU4 A;  3USN A;  2WO9 A;  3VTG A;  1AF0 A;  2J83 A;  1IAA A;  3RTT A;  1GXD A;  1XUC A;  1SAT A;  2OW2 A;  2MZE A;  1R1I A;  2OXU A;  1K7I A;  1XFZ A;  3V96 B;  3KWV C;  3ZXH A;  4AYK A;  3LGP A;  1ROS A;  2POJ A;  4H84 A;  4HX3 A;  1AKL A;  1JAO A;  1XFV A;  3KEJ A;  2W12 A;  1GO7 P;  2JIH A;  5I4O A;  4FXY P;  1UMT A;  1BIW A;  1IAC A;  3LQB A;  3U1R A;  1DMT A;  2D1N A;  4I35 A;  2RJQ A;  3HY7 A;  3HY9 A;  4GR0 A;  2O36 A;  1RMZ A;  3G5C A;  3DNG A;  4XM6 A;  4JIJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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