1USNA

Crystal structure of the catalytic domain of human fibroblast stromelysin-1 inhibited with thiadiazole inhibitor pnu-142372
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
165
structure length
164
Chain Sequence
FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTALMYPLYHSLTDLTRFRLSQDDINGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity.
pubmed rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords STROMELYSIN-1
total genus 45
structure length 164
sequence length 165
ec nomenclature ec 3.4.24.17: Stromelysin 1.
pdb deposition date 1998-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1usnA00
2YB9A 3RTSA 1QIAA 3UVCA 3ZVSA 1R54A 1MMRA 4ILWD 1GKDA 2X7MA 1PWQA 1EAKA 2I47A 4A7BA 1Y0VA 5I43A 1GO7P 3EHXA 3SHIA 4FU4A 3LE9A 4GR8A 3LUNA 2OW0A 3LIRA 2OW1A 1FBLA 1XURA 4HX3A 3F15A 1YCMA 2QPJA 1QICA 4GWMA 1CGEA 3Q2HA 3DPEA 3P24A 2Y6DA 4DF9A 2OVZA 1CQRA 2XS4A 1O0QA 1HFCA 1EB6A 4JPAA 2JSDA 1G9KA 3KECA 4JA1A 2MLSA 1SMPA 2X3BA 3P1VA 1JAQA 3DNGA 1XUDA 1IADA 1HFSA 3EHYA 4PKTA 2K9CA 2TCLA 1C3IA 5JMYA 1G12A 1JK3A 2E2DA 4JP4A 4GWNA 830CA 1D8FA 2D1OA 3AYKA 4PKWA 5CUHA 4H2EA 1HOVA 1KBCA 4XBHA 2KRJA 1BUVM 4XM7A 1GKCA 4AUOA 4PKQA 1D5JA 2CLTA 4H1QA 4GF1A 4WZVA 2YIGA 1XFUA 2K2GA 2A8HA 1OM6A 3KHIA 4QKZA 2AIGP 1BIWA 3HY7A 5D3CA 5L79A 3DPFA 5LABA 1A85A 2X3CA 1UEAA 1UTTA 1B8YA 3I7GA 2J0TA 4ZR5A 2XS3A 4H49A 4I35A 1BSWA 1XUCA 4GR0A 4DV8A 3EDHA 4AIGA 2OVXA 5BPAA 3I7IA 3L0TA 2ERPA 3BA0A 1SU3A 2O36A 2DW1A 4PKSA 1GXDA 3LJTA 2Z2DA 1D8MA 1QUAA 5BOYA 1CIZA 3F16A 2OI0A 1XFYA 1QIBA 3B2ZA 1JIZA 3KMEA 1CAQA 3TS4A 1ZVXA 3KEKA 1YP1A 1KUIA 1I1IP 1OM8A 3N2VA 3DWBA 4XCTA 3KEJA 1UMSA 3HBUP 3ZXHA 1KUHA 1FLSA 1HY7A 2N8RA 3TVCA 1AYKA 3WV3A 5L7FA 3K7LA 1Y8JA 3MA2A 1BQOA 1R1JA 1UTZA 1OM7A 2MLRA 1MMBA 1K7QA 3USNA 3LQ0A 3O2XA 3Q2GA 1PWWA 3OHLA 2CKIA 4GUYA 3HBVP 4H30A 4WK7A 3U1RA 2W14A 1MNCA 4XM8A 1OS2A 3CKIA 1RMZA 3F19A 3G5CA 1BKCA 2W15A 1G49A 3K7NA 2USNA 1IAGA 1JANA 4WF6A 4EFSA 1BKCE 2FV9A 2O3EA 1I76A 3OHOA 1CGFA 1BUDA 4PKUA 3ELMA 2MZEA 1KAPP 1HV5A 3DL1A 4ON1A 1CK7A 3TT4A 5I4OA 3DSLA 1AKLA 3AYUA 3LIKA 3EDGA 4JQGA 5BOTA 3RTTA 2WO9A 1PWPA 1RM8A 1Z3JA 4A3WA 2MZIA 3N2UA 966CA 2E3XA 5CXAA 1Q3AA 3WV1A 1MMQA 1ND1A 3LUMA 1SRPA 1I73A 2DDFA 3F18A 2DDYA 1UMTA 2DW2A 2AYKA 4FXQA 5D1UA 1BM6A 1K7IA 2RJQA 4R3VA 2OXUA 3LGPA 4FXYP 4J4MA 3E8RA 1KUFA 1CGLA 1ROSA 2MZHA 4IN9A 3EWJA 5B5PA 3VTGA 2JT5A 3LK8A 1D7XA 1MMPA 4L63A 1ZXCA 4HMAA 1BKCI 1XFVA 1FM1A 1PWUA 3AIGA 2W0DA 1SLMA 2EROA 5I0LA 1IAEA 4WKIA 2JNPA 4GQLA 1EUBA 3O64A 3LJZA 1R55A 1OS9A 1QJJA 1B3DA 1OMJA 2V4BA 3LILA 1O0TA 5I3MA 4CTHA 2SRTA 1CXVA 1IAAA 3HYGA 2W13A 4PKVA 3ZUKA 5D1SA 4WKEA 4AXQA 3G42A 1ZXVA 1R1IA 4H76A 3EDZA 2OW2A 4G0DA 1JAPA 4H84A 3F17A 4PKRA 1ZS0A 1ZTQA 2W12A 3F1AA 1R1HA 3HB2P 3NX7A 4AYKA 1JH1A 5CZMA 5D1TA 1USNA 3HDBA 2OXZA 1SLNA 3HDAP 4IUWA 1JKYA 2FV5A 456CA 2X3AA 3WV2A 3B92A 3VI1A 1WNIA 4I03A 3KWVC 1QJIA 1G4KA 5I2ZA 3LMCA 1JAOA 2DW0A 1IACA 2D1NA 4L19A 3TSKA 1L6JA 2POJA 3L0VA 5I12A 3KMCA 5B5OA 1HTDA 5D2BA 4DD8A 4DPEA 1XFZA 1KUGA 1PWVA 4IJOA 1JIWP 2RJPA 1DMTA 1C8TA 1YOUA 3B8ZA 4L6TA 1AF0A 2J83A 3LQBA 4JIJA 1C7KA 4H82A 1H71P 3LEAA 5D7WA 1BZSA 1XFWA 4FVLA 2WO8A 1ASTA 1GE5A 1KUKA 1Y93A 1K7GA 2JIHA 2ERQA 1GO8P 3GBOA 1G05A 4Q1LA 1ZP5A 4G9LA 2OY2A 2PJTA 1GE7A 1JJ9A 2HU6A 1S4BP 1BQQM 2OZRA 1A86A 2OW9A 1J7NA 4GR3A 4XM6A 1GE6A 3HY9A 1ATLA 4H3XA 2JT6A 1OO9A 1XFXA 3KRYA 3LJGA 5H8XA 1IABA 1SATA 2WOAA 3EDIA 1YQYA 2OXWA 2OY4A 3LKAA 2L0RA 3V96B 1DTHA 2Y6CA
chains in the Genus database with same CATH superfamily
2YB9A 3RTSA 1QIAA 3UVCA 3ZVSA 1R54A 1MMRA 4ILWD 1GKDA 2X7MA 1PWQA 1EAKA 2I47A 4A7BA 1Y0VA 5I43A 1GO7P 3EHXA 3SHIA 4FU4A 3LE9A 4GR8A 3LUNA 2OW0A 3LIRA 2OW1A 1FBLA 1XURA 4HX3A 3F15A 1YCMA 2QPJA 1QICA 4GWMA 1CGEA 3Q2HA 3DPEA 3P24A 2Y6DA 4DF9A 2OVZA 1CQRA 2XS4A 1O0QA 1HFCA 1EB6A 4JPAA 2JSDA 1G9KA 3KECA 4JA1A 2MLSA 1SMPA 2X3BA 3P1VA 1JAQA 3DNGA 1XUDA 1IADA 1HFSA 3EHYA 4PKTA 2YUFA 2K9CA 2TCLA 1C3IA 5JMYA 1G12A 1JK3A 2E2DA 4JP4A 4GWNA 830CA 1D8FA 2D1OA 3AYKA 4PKWA 5CUHA 4H2EA 1HOVA 1KBCA 4XBHA 2KRJA 1BUVM 4XM7A 1GKCA 4AUOA 4PKQA 1D5JA 2CLTA 4H1QA 4GF1A 4WZVA 2YIGA 1XFUA 2K2GA 2A8HA 1OM6A 3KHIA 4QKZA 2AIGP 1BIWA 3HY7A 5D3CA 5L79A 3DPFA 3DTKA 5LABA 1A85A 2X3CA 1UEAA 1UTTA 1B8YA 3I7GA 2J0TA 4ZR5A 2XS3A 1XM5A 4H49A 4I35A 1BSWA 1XUCA 4GR0A 4DV8A 3EDHA 4AIGA 2OVXA 5BPAA 3I7IA 3L0TA 2ERPA 3BA0A 1SU3A 2O36A 2DW1A 4PKSA 1GXDA 3LJTA 2Z2DA 1D8MA 1QUAA 5BOYA 1CIZA 3F16A 2OI0A 1XFYA 1QIBA 3B2ZA 1JIZA 3KMEA 1CAQA 3TS4A 1ZVXA 3KEKA 1YP1A 1KUIA 1I1IP 1OM8A 3N2VA 3DWBA 4XCTA 3KEJA 1UMSA 3HBUP 3ZXHA 1KUHA 1FLSA 1HY7A 2N8RA 3TVCA 1AYKA 3WV3A 5L7FA 3K7LA 1Y8JA 3MA2A 1BQOA 1R1JA 1UTZA 1OM7A 2MLRA 1MMBA 1K7QA 3USNA 3LQ0A 3O2XA 3Q2GA 1PWWA 3OHLA 2CKIA 4GUYA 3HBVP 4H30A 4WK7A 3U1RA 2W14A 1MNCA 4XM8A 1OS2A 3CKIA 1RMZA 3F19A 3G5CA 1BKCA 2W15A 1G49A 3K7NA 2USNA 1IAGA 1JANA 4WF6A 4EFSA 4L7AA 1BKCE 2FV9A 2O3EA 1I76A 3OHOA 1CGFA 1BUDA 4PKUA 3ELMA 2MZEA 1KAPP 1HV5A 3DL1A 4ON1A 1CK7A 3TT4A 5I4OA 3DSLA 1AKLA 1TVIA 3AYUA 3LIKA 3EDGA 4JQGA 5BOTA 3RTTA 2WO9A 1PWPA 1RM8A 1Z3JA 4A3WA 2MZIA 3N2UA 966CA 2E3XA 5CXAA 1Q3AA 3WV1A 1MMQA 1ND1A 3LUMA 1SRPA 1I73A 2DDFA 3F18A 2DDYA 1UMTA 2DW2A 2AYKA 4FXQA 5D1UA 1BM6A 1K7IA 2RJQA 4R3VA 2OXUA 3LGPA 4FXYP 4J4MA 3E8RA 1KUFA 1CGLA 1ROSA 2MZHA 4IN9A 3EWJA 5B5PA 3VTGA 2JT5A 3LK8A 1D7XA 1MMPA 4L63A 1ZXCA 4HMAA 1BKCI 1XFVA 1FM1A 1PWUA 3AIGA 2W0DA 1SLMA 2EROA 5I0LA 1IAEA 4WKIA 2JNPA 4GQLA 1EUBA 3O64A 3LJZA 1R55A 1OS9A 1QJJA 1B3DA 1OMJA 1OZ9A 1XAXA 2V4BA 3LILA 1O0TA 5I3MA 4CTHA 2SRTA 1CXVA 1IAAA 3HYGA 2W13A 4PKVA 3ZUKA 3DTIA 5D1SA 4WKEA 4AXQA 3G42A 1ZXVA 1R1IA 4H76A 3EDZA 2OW2A 4G0DA 1JAPA 4H84A 3F17A 4PKRA 1ZS0A 1ZTQA 2W12A 3F1AA 1R1HA 3HB2P 3NX7A 4AYKA 1JH1A 5CZMA 5D1TA 1USNA 3HDBA 2OXZA 1SLNA 3HDAP 4IUWA 1JKYA 2FV5A 456CA 2X3AA 3WV2A 3B92A 3VI1A 1WNIA 4I03A 3KWVC 1QJIA 1G4KA 5I2ZA 3LMCA 1JAOA 2DW0A 1IACA 2D1NA 4L19A 3TSKA 1L6JA 2POJA 3L0VA 5I12A 3KMCA 5B5OA 1HTDA 5D2BA 4DD8A 4DPEA 1XFZA 1KUGA 1PWVA 4IJOA 1JIWP 2RJPA 1DMTA 1C8TA 1YOUA 3B8ZA 4L6TA 1AF0A 2J83A 3LQBA 4JIJA 1C7KA 4H82A 1H71P 3LEAA 5D7WA 1BZSA 1XFWA 4FVLA 2WO8A 1ASTA 1GE5A 1KUKA 1Y93A 1K7GA 2JIHA 2ERQA 1GO8P 3GBOA 1G05A 4Q1LA 1ZP5A 4G9LA 2OY2A 2PJTA 1GE7A 1JJ9A 2HU6A 1S4BP 1BQQM 2OZRA 1A86A 2OW9A 1J7NA 4GR3A 4XM6A 1GE6A 3HY9A 1ATLA 4H3XA 2JT6A 1OO9A 1XFXA 3KRYA 3LJGA 5H8XA 1IABA 1SATA 2WOAA 3EDIA 1YQYA 3DTEA 2OXWA 2OY4A 3LKAA 2L0RA 3V96B 1DTHA 2Y6CA
chains in the Genus database with same CATH topology
2YB9A 3RTSA 1QIAA 3UVCA 3ZVSA 1R54A 1MMRA 4ILWD 1GKDA 2X7MA 1PWQA 1EAKA 2I47A 4A7BA 1Y0VA 5I43A 1GO7P 3EHXA 3SHIA 4FU4A 3LE9A 4GR8A 3LUNA 2OW0A 3LIRA 2OW1A 1FBLA 1XURA 4HX3A 3F15A 1YCMA 2QPJA 1QICA 4GWMA 1CGEA 3Q2HA 3DPEA 3P24A 2Y6DA 4DF9A 2OVZA 1CQRA 2XS4A 1O0QA 1HFCA 1EB6A 4JPAA 2JSDA 1G9KA 3KECA 4JA1A 2MLSA 1SMPA 2X3BA 3P1VA 1JAQA 3DNGA 1XUDA 1IADA 1HFSA 3EHYA 4PKTA 2YUFA 2K9CA 2TCLA 1C3IA 5JMYA 1G12A 1JK3A 2E2DA 4JP4A 4GWNA 830CA 1D8FA 2D1OA 3AYKA 4PKWA 5CUHA 4H2EA 1HOVA 1KBCA 4XBHA 2KRJA 1BUVM 4XM7A 1GKCA 4AUOA 4PKQA 1D5JA 2CLTA 4H1QA 4GF1A 4WZVA 2YIGA 1XFUA 2K2GA 2A8HA 1OM6A 3KHIA 4QKZA 2AIGP 1BIWA 3HY7A 5D3CA 5L79A 3DPFA 3DTKA 5LABA 1A85A 2X3CA 1UEAA 1UTTA 1B8YA 3I7GA 2J0TA 4ZR5A 2XS3A 4H49A 4I35A 1BSWA 1XUCA 4GR0A 4DV8A 3EDHA 4AIGA 2OVXA 5BPAA 3I7IA 3L0TA 2ERPA 3BA0A 1SU3A 2O36A 2DW1A 4PKSA 1GXDA 3LJTA 2Z2DA 1D8MA 1QUAA 5BOYA 1CIZA 3F16A 2OI0A 1XFYA 1QIBA 3B2ZA 1JIZA 3KMEA 1CAQA 3TS4A 1ZVXA 3KEKA 1YP1A 1KUIA 1I1IP 1OM8A 3N2VA 3DWBA 4XCTA 3KEJA 1UMSA 3HBUP 3ZXHA 1KUHA 1FLSA 1HY7A 2N8RA 3TVCA 1AYKA 3WV3A 5L7FA 3K7LA 1Y8JA 3MA2A 1BQOA 1R1JA 1UTZA 1OM7A 2MLRA 1MMBA 1K7QA 3USNA 3LQ0A 3O2XA 3Q2GA 1PWWA 3OHLA 2CKIA 4GUYA 3HBVP 4H30A 4WK7A 3U1RA 2W14A 1MNCA 4XM8A 1OS2A 3CKIA 1RMZA 3F19A 3G5CA 1BKCA 2W15A 1G49A 3K7NA 2USNA 1IAGA 1JANA 4WF6A 4EFSA 4L7AA 1BKCE 2FV9A 2O3EA 1I76A 3OHOA 1CGFA 1BUDA 4PKUA 3ELMA 2MZEA 1KAPP 1HV5A 3DL1A 4ON1A 1CK7A 3TT4A 5I4OA 3DSLA 1AKLA 3AYUA 3LIKA 3EDGA 4JQGA 5BOTA 3RTTA 2WO9A 1PWPA 1RM8A 1Z3JA 4A3WA 2MZIA 3N2UA 966CA 2E3XA 5CXAA 1Q3AA 3WV1A 1MMQA 1ND1A 3LUMA 1SRPA 1I73A 2DDFA 3F18A 2DDYA 1UMTA 2DW2A 2AYKA 4FXQA 5D1UA 1BM6A 1K7IA 2RJQA 4R3VA 2OXUA 3LGPA 4FXYP 4J4MA 3E8RA 1KUFA 1CGLA 1ROSA 2MZHA 4IN9A 3EWJA 5B5PA 3VTGA 2JT5A 3LK8A 1D7XA 1MMPA 4L63A 1ZXCA 4HMAA 1BKCI 1XFVA 1FM1A 1PWUA 3AIGA 2W0DA 1SLMA 2EROA 5I0LA 1IAEA 4WKIA 2JNPA 4GQLA 1EUBA 3O64A 3LJZA 1R55A 1OS9A 1QJJA 1B3DA 1OMJA 2V4BA 3LILA 1O0TA 5I3MA 4CTHA 2SRTA 1CXVA 1IAAA 3HYGA 2W13A 4PKVA 3ZUKA 3DTIA 5D1SA 4WKEA 4AXQA 3G42A 1ZXVA 1R1IA 4H76A 3EDZA 2OW2A 4G0DA 1JAPA 4H84A 3F17A 4PKRA 1ZS0A 1ZTQA 2W12A 3F1AA 1R1HA 3HB2P 3NX7A 4AYKA 1JH1A 5CZMA 5D1TA 1USNA 3HDBA 2OXZA 1SLNA 3HDAP 4IUWA 1JKYA 2FV5A 456CA 2X3AA 3WV2A 3B92A 3VI1A 1WNIA 4I03A 3KWVC 1QJIA 1G4KA 5I2ZA 3LMCA 1JAOA 2DW0A 1IACA 2D1NA 4L19A 3TSKA 1L6JA 2POJA 3L0VA 5I12A 3KMCA 5B5OA 1HTDA 5D2BA 4DD8A 4DPEA 1XFZA 1KUGA 1PWVA 4IJOA 1JIWP 2RJPA 1DMTA 1C8TA 1YOUA 3B8ZA 4L6TA 1AF0A 2J83A 3LQBA 4JIJA 1C7KA 4H82A 1H71P 3LEAA 5D7WA 1BZSA 1XFWA 4FVLA 2WO8A 1ASTA 1GE5A 1KUKA 1Y93A 1K7GA 2JIHA 2ERQA 1GO8P 3GBOA 1G05A 4Q1LA 1ZP5A 4G9LA 2OY2A 2PJTA 1GE7A 1JJ9A 2HU6A 1S4BP 1BQQM 2OZRA 1A86A 2OW9A 1J7NA 4GR3A 4XM6A 1GE6A 3HY9A 1ATLA 4H3XA 2JT6A 1OO9A 1XFXA 3KRYA 3LJGA 5H8XA 1IABA 1SATA 2WOAA 3EDIA 1YQYA 3DTEA 2OXWA 2OY4A 3LKAA 2L0RA 3V96B 1DTHA 2Y6CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YB9 A;  3RTS A;  1QIA A;  3UVC A;  3ZVS A;  1R54 A;  1MMR A;  4ILW D;  1GKD A;  2X7M A;  1PWQ A;  1EAK A;  2I47 A;  4A7B A;  1Y0V A;  5I43 A;  1GO7 P;  3EHX A;  3SHI A;  4FU4 A;  3LE9 A;  4GR8 A;  3LUN A;  2OW0 A;  3LIR A;  2OW1 A;  1FBL A;  1XUR A;  4HX3 A;  3F15 A;  1YCM A;  2QPJ A;  1QIC A;  4GWM A;  1CGE A;  3Q2H A;  3DPE A;  3P24 A;  2Y6D A;  4DF9 A;  2OVZ A;  1CQR A;  2XS4 A;  1O0Q A;  1HFC A;  1EB6 A;  4JPA A;  2JSD A;  1G9K A;  3KEC A;  4JA1 A;  2MLS A;  1SMP A;  2X3B A;  3P1V A;  1JAQ A;  3DNG A;  1XUD A;  1IAD A;  1HFS A;  3EHY A;  4PKT A;  2K9C A;  2TCL A;  1C3I A;  5JMY A;  1G12 A;  1JK3 A;  2E2D A;  4JP4 A;  4GWN A;  830C A;  1D8F A;  2D1O A;  3AYK A;  4PKW A;  5CUH A;  4H2E A;  1HOV A;  1KBC A;  4XBH A;  2KRJ A;  1BUV M;  4XM7 A;  1GKC A;  4AUO A;  4PKQ A;  1D5J A;  2CLT A;  4H1Q A;  4GF1 A;  4WZV A;  2YIG A;  1XFU A;  2K2G A;  2A8H A;  1OM6 A;  3KHI A;  4QKZ A;  2AIG P;  1BIW A;  3HY7 A;  5D3C A;  5L79 A;  3DPF A;  5LAB A;  1A85 A;  2X3C A;  1UEA A;  1UTT A;  1B8Y A;  3I7G A;  2J0T A;  4ZR5 A;  2XS3 A;  4H49 A;  4I35 A;  1BSW A;  1XUC A;  4GR0 A;  4DV8 A;  3EDH A;  4AIG A;  2OVX A;  5BPA A;  3I7I A;  3L0T A;  2ERP A;  3BA0 A;  1SU3 A;  2O36 A;  2DW1 A;  4PKS A;  1GXD A;  3LJT A;  2Z2D A;  1D8M A;  1QUA A;  5BOY A;  1CIZ A;  3F16 A;  2OI0 A;  1XFY A;  1QIB A;  3B2Z A;  1JIZ A;  3KME A;  1CAQ A;  3TS4 A;  1ZVX A;  3KEK A;  1YP1 A;  1KUI A;  1I1I P;  1OM8 A;  3N2V A;  3DWB A;  4XCT A;  3KEJ A;  1UMS A;  3HBU P;  3ZXH A;  1KUH A;  1FLS A;  1HY7 A;  2N8R A;  3TVC A;  1AYK A;  3WV3 A;  5L7F A;  3K7L A;  1Y8J A;  3MA2 A;  1BQO A;  1R1J A;  1UTZ A;  1OM7 A;  2MLR A;  1MMB A;  1K7Q A;  3USN A;  3LQ0 A;  3O2X A;  3Q2G A;  1PWW A;  3OHL A;  2CKI A;  4GUY A;  3HBV P;  4H30 A;  4WK7 A;  3U1R A;  2W14 A;  1MNC A;  4XM8 A;  1OS2 A;  3CKI A;  1RMZ A;  3F19 A;  3G5C A;  1BKC A;  2W15 A;  1G49 A;  3K7N A;  2USN A;  1IAG A;  1JAN A;  4WF6 A;  4EFS A;  1BKC E;  2FV9 A;  2O3E A;  1I76 A;  3OHO A;  1CGF A;  1BUD A;  4PKU A;  3ELM A;  2MZE A;  1KAP P;  1HV5 A;  3DL1 A;  4ON1 A;  1CK7 A;  3TT4 A;  5I4O A;  3DSL A;  1AKL A;  3AYU A;  3LIK A;  3EDG A;  4JQG A;  5BOT A;  3RTT A;  2WO9 A;  1PWP A;  1RM8 A;  1Z3J A;  4A3W A;  2MZI A;  3N2U A;  966C A;  2E3X A;  5CXA A;  1Q3A A;  3WV1 A;  1MMQ A;  1ND1 A;  3LUM A;  1SRP A;  1I73 A;  2DDF A;  3F18 A;  2DDY A;  1UMT A;  2DW2 A;  2AYK A;  4FXQ A;  5D1U A;  1BM6 A;  1K7I A;  2RJQ A;  4R3V A;  2OXU A;  3LGP A;  4FXY P;  4J4M A;  3E8R A;  1KUF A;  1CGL A;  1ROS A;  2MZH A;  4IN9 A;  3EWJ A;  5B5P A;  3VTG A;  2JT5 A;  3LK8 A;  1D7X A;  1MMP A;  4L63 A;  1ZXC A;  4HMA A;  1BKC I;  1XFV A;  1FM1 A;  1PWU A;  3AIG A;  2W0D A;  1SLM A;  2ERO A;  5I0L A;  1IAE A;  4WKI A;  2JNP A;  4GQL A;  1EUB A;  3O64 A;  3LJZ A;  1R55 A;  1OS9 A;  1QJJ A;  1B3D A;  1OMJ A;  2V4B A;  3LIL A;  1O0T A;  5I3M A;  4CTH A;  2SRT A;  1CXV A;  1IAA A;  3HYG A;  2W13 A;  4PKV A;  3ZUK A;  5D1S A;  4WKE A;  4AXQ A;  3G42 A;  1ZXV A;  1R1I A;  4H76 A;  3EDZ A;  2OW2 A;  4G0D A;  1JAP A;  4H84 A;  3F17 A;  4PKR A;  1ZS0 A;  1ZTQ A;  2W12 A;  3F1A A;  1R1H A;  3HB2 P;  3NX7 A;  4AYK A;  1JH1 A;  5CZM A;  5D1T A;  1USN A;  3HDB A;  2OXZ A;  1SLN A;  3HDA P;  4IUW A;  1JKY A;  2FV5 A;  456C A;  2X3A A;  3WV2 A;  3B92 A;  3VI1 A;  1WNI A;  4I03 A;  3KWV C;  1QJI A;  1G4K A;  5I2Z A;  3LMC A;  1JAO A;  2DW0 A;  1IAC A;  2D1N A;  4L19 A;  3TSK A;  1L6J A;  2POJ A;  3L0V A;  5I12 A;  3KMC A;  5B5O A;  1HTD A;  5D2B A;  4DD8 A;  4DPE A;  1XFZ A;  1KUG A;  1PWV A;  4IJO A;  1JIW P;  2RJP A;  1DMT A;  1C8T A;  1YOU A;  3B8Z A;  4L6T A;  1AF0 A;  2J83 A;  3LQB A;  4JIJ A;  1C7K A;  4H82 A;  1H71 P;  3LEA A;  5D7W A;  1BZS A;  1XFW A;  4FVL A;  2WO8 A;  1AST A;  1GE5 A;  1KUK A;  1Y93 A;  1K7G A;  2JIH A;  2ERQ A;  1GO8 P;  3GBO A;  1G05 A;  4Q1L A;  1ZP5 A;  4G9L A;  2OY2 A;  2PJT A;  1GE7 A;  1JJ9 A;  2HU6 A;  1S4B P;  1BQQ M;  2OZR A;  1A86 A;  2OW9 A;  1J7N A;  4GR3 A;  4XM6 A;  1GE6 A;  3HY9 A;  1ATL A;  4H3X A;  2JT6 A;  1OO9 A;  1XFX A;  3KRY A;  3LJG A;  5H8X A;  1IAB A;  1SAT A;  2WOA A;  3EDI A;  1YQY A;  2OXW A;  2OY4 A;  3LKA A;  2L0R A;  3V96 B;  1DTH A;  2Y6C A; 
#chains in the Genus database with same CATH topology
 2YB9 A;  3RTS A;  1QIA A;  3UVC A;  3ZVS A;  1R54 A;  1MMR A;  4ILW D;  1GKD A;  2X7M A;  1PWQ A;  1EAK A;  2I47 A;  4A7B A;  1Y0V A;  5I43 A;  1GO7 P;  3EHX A;  3SHI A;  4FU4 A;  3LE9 A;  4GR8 A;  3LUN A;  2OW0 A;  3LIR A;  2OW1 A;  1FBL A;  1XUR A;  4HX3 A;  3F15 A;  1YCM A;  2QPJ A;  1QIC A;  4GWM A;  1CGE A;  3Q2H A;  3DPE A;  3P24 A;  2Y6D A;  4DF9 A;  2OVZ A;  1CQR A;  2XS4 A;  1O0Q A;  1HFC A;  1EB6 A;  4JPA A;  2JSD A;  1G9K A;  3KEC A;  4JA1 A;  2MLS A;  1SMP A;  2X3B A;  3P1V A;  1JAQ A;  3DNG A;  1XUD A;  1IAD A;  1HFS A;  3EHY A;  4PKT A;  2YUF A;  2K9C A;  2TCL A;  1C3I A;  5JMY A;  1G12 A;  1JK3 A;  2E2D A;  4JP4 A;  4GWN A;  830C A;  1D8F A;  2D1O A;  3AYK A;  4PKW A;  5CUH A;  4H2E A;  1HOV A;  1KBC A;  4XBH A;  2KRJ A;  1BUV M;  4XM7 A;  1GKC A;  4AUO A;  4PKQ A;  1D5J A;  2CLT A;  4H1Q A;  4GF1 A;  4WZV A;  2YIG A;  1XFU A;  2K2G A;  2A8H A;  1OM6 A;  3KHI A;  4QKZ A;  2AIG P;  1BIW A;  3HY7 A;  5D3C A;  5L79 A;  3DPF A;  3DTK A;  5LAB A;  1A85 A;  2X3C A;  1UEA A;  1UTT A;  1B8Y A;  3I7G A;  2J0T A;  4ZR5 A;  2XS3 A;  1XM5 A;  4H49 A;  4I35 A;  1BSW A;  1XUC A;  4GR0 A;  4DV8 A;  3EDH A;  4AIG A;  2OVX A;  5BPA A;  3I7I A;  3L0T A;  2ERP A;  3BA0 A;  1SU3 A;  2O36 A;  2DW1 A;  4PKS A;  1GXD A;  3LJT A;  2Z2D A;  1D8M A;  1QUA A;  5BOY A;  1CIZ A;  3F16 A;  2OI0 A;  1XFY A;  1QIB A;  3B2Z A;  1JIZ A;  3KME A;  1CAQ A;  3TS4 A;  1ZVX A;  3KEK A;  1YP1 A;  1KUI A;  1I1I P;  1OM8 A;  3N2V A;  3DWB A;  4XCT A;  3KEJ A;  1UMS A;  3HBU P;  3ZXH A;  1KUH A;  1FLS A;  1HY7 A;  2N8R A;  3TVC A;  1AYK A;  3WV3 A;  5L7F A;  3K7L A;  1Y8J A;  3MA2 A;  1BQO A;  1R1J A;  1UTZ A;  1OM7 A;  2MLR A;  1MMB A;  1K7Q A;  3USN A;  3LQ0 A;  3O2X A;  3Q2G A;  1PWW A;  3OHL A;  2CKI A;  4GUY A;  3HBV P;  4H30 A;  4WK7 A;  3U1R A;  2W14 A;  1MNC A;  4XM8 A;  1OS2 A;  3CKI A;  1RMZ A;  3F19 A;  3G5C A;  1BKC A;  2W15 A;  1G49 A;  3K7N A;  2USN A;  1IAG A;  1JAN A;  4WF6 A;  4EFS A;  4L7A A;  1BKC E;  2FV9 A;  2O3E A;  1I76 A;  3OHO A;  1CGF A;  1BUD A;  4PKU A;  3ELM A;  2MZE A;  1KAP P;  1HV5 A;  3DL1 A;  4ON1 A;  1CK7 A;  3TT4 A;  5I4O A;  3DSL A;  1AKL A;  1TVI A;  3AYU A;  3LIK A;  3EDG A;  4JQG A;  5BOT A;  3RTT A;  2WO9 A;  1PWP A;  1RM8 A;  1Z3J A;  4A3W A;  2MZI A;  3N2U A;  966C A;  2E3X A;  5CXA A;  1Q3A A;  3WV1 A;  1MMQ A;  1ND1 A;  3LUM A;  1SRP A;  1I73 A;  2DDF A;  3F18 A;  2DDY A;  1UMT A;  2DW2 A;  2AYK A;  4FXQ A;  5D1U A;  1BM6 A;  1K7I A;  2RJQ A;  4R3V A;  2OXU A;  3LGP A;  4FXY P;  4J4M A;  3E8R A;  1KUF A;  1CGL A;  1ROS A;  2MZH A;  4IN9 A;  3EWJ A;  5B5P A;  3VTG A;  2JT5 A;  3LK8 A;  1D7X A;  1MMP A;  4L63 A;  1ZXC A;  4HMA A;  1BKC I;  1XFV A;  1FM1 A;  1PWU A;  3AIG A;  2W0D A;  1SLM A;  2ERO A;  5I0L A;  1IAE A;  4WKI A;  2JNP A;  4GQL A;  1EUB A;  3O64 A;  3LJZ A;  1R55 A;  1OS9 A;  1QJJ A;  1B3D A;  1OMJ A;  1OZ9 A;  1XAX A;  2V4B A;  3LIL A;  1O0T A;  5I3M A;  4CTH A;  2SRT A;  1CXV A;  1IAA A;  3HYG A;  2W13 A;  4PKV A;  3ZUK A;  3DTI A;  5D1S A;  4WKE A;  4AXQ A;  3G42 A;  1ZXV A;  1R1I A;  4H76 A;  3EDZ A;  2OW2 A;  4G0D A;  1JAP A;  4H84 A;  3F17 A;  4PKR A;  1ZS0 A;  1ZTQ A;  2W12 A;  3F1A A;  1R1H A;  3HB2 P;  3NX7 A;  4AYK A;  1JH1 A;  5CZM A;  5D1T A;  1USN A;  3HDB A;  2OXZ A;  1SLN A;  3HDA P;  4IUW A;  1JKY A;  2FV5 A;  456C A;  2X3A A;  3WV2 A;  3B92 A;  3VI1 A;  1WNI A;  4I03 A;  3KWV C;  1QJI A;  1G4K A;  5I2Z A;  3LMC A;  1JAO A;  2DW0 A;  1IAC A;  2D1N A;  4L19 A;  3TSK A;  1L6J A;  2POJ A;  3L0V A;  5I12 A;  3KMC A;  5B5O A;  1HTD A;  5D2B A;  4DD8 A;  4DPE A;  1XFZ A;  1KUG A;  1PWV A;  4IJO A;  1JIW P;  2RJP A;  1DMT A;  1C8T A;  1YOU A;  3B8Z A;  4L6T A;  1AF0 A;  2J83 A;  3LQB A;  4JIJ A;  1C7K A;  4H82 A;  1H71 P;  3LEA A;  5D7W A;  1BZS A;  1XFW A;  4FVL A;  2WO8 A;  1AST A;  1GE5 A;  1KUK A;  1Y93 A;  1K7G A;  2JIH A;  2ERQ A;  1GO8 P;  3GBO A;  1G05 A;  4Q1L A;  1ZP5 A;  4G9L A;  2OY2 A;  2PJT A;  1GE7 A;  1JJ9 A;  2HU6 A;  1S4B P;  1BQQ M;  2OZR A;  1A86 A;  2OW9 A;  1J7N A;  4GR3 A;  4XM6 A;  1GE6 A;  3HY9 A;  1ATL A;  4H3X A;  2JT6 A;  1OO9 A;  1XFX A;  3KRY A;  3LJG A;  5H8X A;  1IAB A;  1SAT A;  2WOA A;  3EDI A;  1YQY A;  3DTE A;  2OXW A;  2OY4 A;  3LKA A;  2L0R A;  3V96 B;  1DTH A;  2Y6C A; 
#chains in the Genus database with same CATH homology
 2YB9 A;  3RTS A;  1QIA A;  3UVC A;  3ZVS A;  1R54 A;  1MMR A;  4ILW D;  1GKD A;  2X7M A;  1PWQ A;  1EAK A;  2I47 A;  4A7B A;  1Y0V A;  5I43 A;  1GO7 P;  3EHX A;  3SHI A;  4FU4 A;  3LE9 A;  4GR8 A;  3LUN A;  2OW0 A;  3LIR A;  2OW1 A;  1FBL A;  1XUR A;  4HX3 A;  3F15 A;  1YCM A;  2QPJ A;  1QIC A;  4GWM A;  1CGE A;  3Q2H A;  3DPE A;  3P24 A;  2Y6D A;  4DF9 A;  2OVZ A;  1CQR A;  2XS4 A;  1O0Q A;  1HFC A;  1EB6 A;  4JPA A;  2JSD A;  1G9K A;  3KEC A;  4JA1 A;  2MLS A;  1SMP A;  2X3B A;  3P1V A;  1JAQ A;  3DNG A;  1XUD A;  1IAD A;  1HFS A;  3EHY A;  4PKT A;  2YUF A;  2K9C A;  2TCL A;  1C3I A;  5JMY A;  1G12 A;  1JK3 A;  2E2D A;  4JP4 A;  4GWN A;  830C A;  1D8F A;  2D1O A;  3AYK A;  4PKW A;  5CUH A;  4H2E A;  1HOV A;  1KBC A;  4XBH A;  2KRJ A;  1BUV M;  4XM7 A;  1GKC A;  4AUO A;  4PKQ A;  1D5J A;  2CLT A;  4H1Q A;  4GF1 A;  4WZV A;  2YIG A;  1XFU A;  2K2G A;  2A8H A;  1OM6 A;  3KHI A;  4QKZ A;  2AIG P;  1BIW A;  3HY7 A;  5D3C A;  5L79 A;  3DPF A;  3DTK A;  5LAB A;  1A85 A;  2X3C A;  1UEA A;  1UTT A;  1B8Y A;  3I7G A;  2J0T A;  4ZR5 A;  2XS3 A;  4H49 A;  4I35 A;  1BSW A;  1XUC A;  4GR0 A;  4DV8 A;  3EDH A;  4AIG A;  2OVX A;  5BPA A;  3I7I A;  3L0T A;  2ERP A;  3BA0 A;  1SU3 A;  2O36 A;  2DW1 A;  4PKS A;  1GXD A;  3LJT A;  2Z2D A;  1D8M A;  1QUA A;  5BOY A;  1CIZ A;  3F16 A;  2OI0 A;  1XFY A;  1QIB A;  3B2Z A;  1JIZ A;  3KME A;  1CAQ A;  3TS4 A;  1ZVX A;  3KEK A;  1YP1 A;  1KUI A;  1I1I P;  1OM8 A;  3N2V A;  3DWB A;  4XCT A;  3KEJ A;  1UMS A;  3HBU P;  3ZXH A;  1KUH A;  1FLS A;  1HY7 A;  2N8R A;  3TVC A;  1AYK A;  3WV3 A;  5L7F A;  3K7L A;  1Y8J A;  3MA2 A;  1BQO A;  1R1J A;  1UTZ A;  1OM7 A;  2MLR A;  1MMB A;  1K7Q A;  3USN A;  3LQ0 A;  3O2X A;  3Q2G A;  1PWW A;  3OHL A;  2CKI A;  4GUY A;  3HBV P;  4H30 A;  4WK7 A;  3U1R A;  2W14 A;  1MNC A;  4XM8 A;  1OS2 A;  3CKI A;  1RMZ A;  3F19 A;  3G5C A;  1BKC A;  2W15 A;  1G49 A;  3K7N A;  2USN A;  1IAG A;  1JAN A;  4WF6 A;  4EFS A;  4L7A A;  1BKC E;  2FV9 A;  2O3E A;  1I76 A;  3OHO A;  1CGF A;  1BUD A;  4PKU A;  3ELM A;  2MZE A;  1KAP P;  1HV5 A;  3DL1 A;  4ON1 A;  1CK7 A;  3TT4 A;  5I4O A;  3DSL A;  1AKL A;  3AYU A;  3LIK A;  3EDG A;  4JQG A;  5BOT A;  3RTT A;  2WO9 A;  1PWP A;  1RM8 A;  1Z3J A;  4A3W A;  2MZI A;  3N2U A;  966C A;  2E3X A;  5CXA A;  1Q3A A;  3WV1 A;  1MMQ A;  1ND1 A;  3LUM A;  1SRP A;  1I73 A;  2DDF A;  3F18 A;  2DDY A;  1UMT A;  2DW2 A;  2AYK A;  4FXQ A;  5D1U A;  1BM6 A;  1K7I A;  2RJQ A;  4R3V A;  2OXU A;  3LGP A;  4FXY P;  4J4M A;  3E8R A;  1KUF A;  1CGL A;  1ROS A;  2MZH A;  4IN9 A;  3EWJ A;  5B5P A;  3VTG A;  2JT5 A;  3LK8 A;  1D7X A;  1MMP A;  4L63 A;  1ZXC A;  4HMA A;  1BKC I;  1XFV A;  1FM1 A;  1PWU A;  3AIG A;  2W0D A;  1SLM A;  2ERO A;  5I0L A;  1IAE A;  4WKI A;  2JNP A;  4GQL A;  1EUB A;  3O64 A;  3LJZ A;  1R55 A;  1OS9 A;  1QJJ A;  1B3D A;  1OMJ A;  2V4B A;  3LIL A;  1O0T A;  5I3M A;  4CTH A;  2SRT A;  1CXV A;  1IAA A;  3HYG A;  2W13 A;  4PKV A;  3ZUK A;  3DTI A;  5D1S A;  4WKE A;  4AXQ A;  3G42 A;  1ZXV A;  1R1I A;  4H76 A;  3EDZ A;  2OW2 A;  4G0D A;  1JAP A;  4H84 A;  3F17 A;  4PKR A;  1ZS0 A;  1ZTQ A;  2W12 A;  3F1A A;  1R1H A;  3HB2 P;  3NX7 A;  4AYK A;  1JH1 A;  5CZM A;  5D1T A;  1USN A;  3HDB A;  2OXZ A;  1SLN A;  3HDA P;  4IUW A;  1JKY A;  2FV5 A;  456C A;  2X3A A;  3WV2 A;  3B92 A;  3VI1 A;  1WNI A;  4I03 A;  3KWV C;  1QJI A;  1G4K A;  5I2Z A;  3LMC A;  1JAO A;  2DW0 A;  1IAC A;  2D1N A;  4L19 A;  3TSK A;  1L6J A;  2POJ A;  3L0V A;  5I12 A;  3KMC A;  5B5O A;  1HTD A;  5D2B A;  4DD8 A;  4DPE A;  1XFZ A;  1KUG A;  1PWV A;  4IJO A;  1JIW P;  2RJP A;  1DMT A;  1C8T A;  1YOU A;  3B8Z A;  4L6T A;  1AF0 A;  2J83 A;  3LQB A;  4JIJ A;  1C7K A;  4H82 A;  1H71 P;  3LEA A;  5D7W A;  1BZS A;  1XFW A;  4FVL A;  2WO8 A;  1AST A;  1GE5 A;  1KUK A;  1Y93 A;  1K7G A;  2JIH A;  2ERQ A;  1GO8 P;  3GBO A;  1G05 A;  4Q1L A;  1ZP5 A;  4G9L A;  2OY2 A;  2PJT A;  1GE7 A;  1JJ9 A;  2HU6 A;  1S4B P;  1BQQ M;  2OZR A;  1A86 A;  2OW9 A;  1J7N A;  4GR3 A;  4XM6 A;  1GE6 A;  3HY9 A;  1ATL A;  4H3X A;  2JT6 A;  1OO9 A;  1XFX A;  3KRY A;  3LJG A;  5H8X A;  1IAB A;  1SAT A;  2WOA A;  3EDI A;  1YQY A;  3DTE A;  2OXW A;  2OY4 A;  3LKA A;  2L0R A;  3V96 B;  1DTH A;  2Y6C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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