2DDFA

Crystal structure of tace in complex with tapi-2
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
257
structure length
253
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADAM 17
publication title Stabilization of the autoproteolysis of TNF-alpha converting enzyme (TACE) results in a novel crystal form suitable for structure-based drug design studies.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 82
structure length 253
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2006-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2ddfA00
1CAQA 4JP4A 2X7MA 1CK7A 2MZEA 2CLTA 1HV5A 4I03A 3B92A 3VI1A 2L0RA 1SATA 4GWNA 1RM8A 1FM1A 4H76A 1D5JA 1G9KA 1XFYA 1HY7A 1OM8A 2K9CA 3EWJA 3EDIA 1XURA 4IN9A 5CUHA 2JT5A 1H71P 2O3EA 4I35A 1FLSA 3Q2GA 4AUOA 2POJA 2J83A 2W13A 4CTHA 4IJOA 830CA 4R3VA 1BQOA 5B5OA 2W15A 1JH1A 4G9LA 5D7WA 2QPJA 4GR0A 5CXAA 1QIBA 3DPEA 4IUWA 1ROSA 1KUKA 1BZSA 5JMYA 3KEKA 3LUNA 4ON1A 3EHXA 4PKVA 1Y0VA 2I47A 2WO8A 2XS4A 1MMRA 2OW1A 4JQGA 1JANA 4L19A 4XM6A 4L6TA 2Z2DA 1B8YA 3KECA 3U1RA 1BKCA 1O0QA 1ZTQA 4HX3A 4AIGA 4PKQA 1G49A 3NX7A 1BM6A 4FXQA 3WV2A 2MLSA 1QJIA 3F17A 3TT4A 5I2ZA 1PWVA 5L7FA 3EDZA 1JIWP 3AYKA 1IAAA 1GO8P 1QICA 4WKEA 1S4BP 1KAPP 5BOYA 4HMAA 1A86A 1KUHA 5H8XA 1XFVA 2O36A 2WOAA 1AF0A 4PKTA 2ERQA 3KHIA 2SRTA 3G5CA 1A85A 1QUAA 1GE7A 2FV5A 3DNGA 1FBLA 3LKAA 4PKUA 4DPEA 4XBHA 1XFUA 2V4BA 1K7GA 1UMSA 1GKDA 4H30A 4L63A 4XM7A 4DV8A 1ZS0A 3AIGA 3N2UA 3HY9A 4GWMA 3SHIA 3CKIA 3LIKA 4PKRA 1D7XA 4WZVA 2HU6A 1JAPA 3DSLA 2D1NA 5L79A 3K7NA 1SU3A 2OZRA 3MA2A 2FV9A 1QIAA 1Y8JA 2OVZA 3LMCA 1WNIA 1C3IA 1CQRA 1JKYA 2W0DA 4J4MA 1K7IA 3L0TA 1J7NA 2ERPA 4FXYP 1BQQM 3LUMA 1R55A 5D1UA 1MMPA 3BA0A 5I12A 2OW2A 2X3AA 4Q1LA 1GO7P 2JIHA 4AXQA 1IAGA 2USNA 4H84A 2X3BA 2E3XA 2DDFA 1PWUA 2OW9A 1ZVXA 1CGEA 1ZP5A 4H1QA 1XFZA 3RTSA 4A7BA 3DWBA 2OXUA 3F1AA 2W14A 3KEJA 3O64A 1XUDA 1BKCE 2OVXA 1CGFA 1I73A 1JJ9A 3I7GA 1DMTA 3KMCA 3LK8A 4ILWD 4FU4A 5D1SA 3TVCA 1YQYA 1G12A 4PKSA 1CIZA 1YP1A 3DPFA 1EAKA 1XFWA 3DL1A 2RJPA 1G4KA 4PKWA 4GR8A 1MNCA 5D1TA 1OO9A 5BOTA 1IABA 3I7IA 1UTZA 4GR3A 2JSDA 1BSWA 2OY2A 1Z3JA 3ZXHA 1HFSA 2W12A 1QJJA 4EFSA 3KWVC 2J0TA 2OI0A 3B2ZA 4WKIA 2MZIA 2Y6CA 3N2VA 2N8RA 4GQLA 3V96B 2X3CA 1JAOA 1IAEA 1K7QA 2MZHA 1L6JA 3E8RA 1GKCA 1SMPA 4H3XA 3P24A 1XFXA 3GBOA 2OW0A 1SRPA 1HOVA 2PJTA 3LGPA 1JAQA 1R1JA 1AKLA 1CGLA 1ATLA 1R1HA 1UEAA 1KUFA 3F18A 1I1IP 1I76A 3WV1A 1DTHA 3LE9A 3KMEA 2D1OA 4FVLA 3G42A 2MLRA 5BPAA 3HBVP 966CA 1CXVA 1SLNA 1OM7A 1C8TA 2DW2A 3F15A 2TCLA 3HDAP 2E2DA 1GE6A 1HFCA 2YB9A 2XS3A 1C7KA 4G0DA 1G05A 4JA1A 1OS2A 4ZR5A 5D3CA 5LABA 3LQBA 1OMJA 2A8HA 1XUCA 3OHOA 4H2EA 2YIGA 5B5PA 2DW1A 1R54A 3EDGA 3F19A 2K2GA 3TS4A 2JT6A 1KBCA 5I3MA 2OY4A 3EHYA 3K7LA 4H49A 3LQ0A 1OS9A 3ZUKA 1YCMA 2OXWA 5CZMA 3L0VA 1ASTA 2AYKA 3ZVSA 1OM6A 1O0TA 1BUDA 4XCTA 1IADA 2WO9A 1KUGA 1PWWA 1PWPA 1R1IA 2RJQA 4WF6A 1JK3A 3UVCA 2CKIA 1EB6A 3O2XA 1UTTA 3HDBA 1Y93A 3P1VA 3B8ZA 1D8FA 1BKCI 5D2BA 5I4OA 3KRYA 2KRJA 3WV3A 1PWQA 1MMBA 4H82A 3LEAA 2DW0A 4GF1A 4GUYA 3RTTA 2JNPA 1ZXCA 4DF9A 3HY7A 2Y6DA 1AYKA 3VTGA 4A3WA 3LJZA 4XM8A 1SLMA 3LJTA 3OHLA 4QKZA 3USNA 4WK7A 2OXZA 3LIRA 3LILA 1MMQA 2EROA 3AYUA 1GXDA 5I0LA 4JIJA 4DD8A 3EDHA 4JPAA 2AIGP 1BIWA 1D8MA 5I43A 3HYGA 3TSKA 4AYKA 1HTDA 2DDYA 1EUBA 3Q2HA 3HBUP 1BUVM 1YOUA 456CA 3LJGA 1JIZA 1GE5A 1USNA 1Q3AA 1UMTA 1ND1A 3ELMA 1B3DA 1ZXVA 1IACA 3F16A 1KUIA 3HB2P 1RMZA
chains in the Genus database with same CATH superfamily
1CAQA 4JP4A 2X7MA 1CK7A 2MZEA 2CLTA 1HV5A 4I03A 3B92A 3VI1A 2L0RA 1SATA 4GWNA 1RM8A 1FM1A 4H76A 1XM5A 1D5JA 1G9KA 1XFYA 1HY7A 1OM8A 2K9CA 3EWJA 3EDIA 1XURA 4IN9A 5CUHA 2JT5A 1H71P 2O3EA 4I35A 1FLSA 3Q2GA 4AUOA 2POJA 2J83A 2W13A 4CTHA 4IJOA 830CA 4R3VA 1BQOA 5B5OA 2W15A 1JH1A 4G9LA 5D7WA 2QPJA 4GR0A 5CXAA 1QIBA 3DPEA 4IUWA 1ROSA 1KUKA 1BZSA 5JMYA 3KEKA 3LUNA 4ON1A 3EHXA 4PKVA 1Y0VA 2I47A 2WO8A 2XS4A 1MMRA 2OW1A 4JQGA 1JANA 4L19A 4XM6A 4L6TA 2Z2DA 1B8YA 3KECA 3U1RA 1BKCA 1O0QA 1ZTQA 4L7AA 4HX3A 4AIGA 4PKQA 1G49A 3NX7A 1BM6A 4FXQA 3WV2A 2MLSA 1QJIA 3F17A 3TT4A 5I2ZA 1PWVA 1OZ9A 5L7FA 3EDZA 1JIWP 3AYKA 1IAAA 1GO8P 1QICA 4WKEA 1S4BP 1KAPP 5BOYA 4HMAA 1A86A 1KUHA 5H8XA 1XFVA 2O36A 2WOAA 1AF0A 4PKTA 2ERQA 3KHIA 2SRTA 3G5CA 1A85A 1QUAA 1GE7A 2FV5A 3DNGA 1FBLA 3LKAA 4PKUA 4DPEA 4XBHA 1XFUA 2V4BA 1K7GA 1UMSA 1GKDA 4H30A 4L63A 4XM7A 4DV8A 1ZS0A 3AIGA 3N2UA 3HY9A 4GWMA 3SHIA 3CKIA 3LIKA 4PKRA 1D7XA 4WZVA 2HU6A 1JAPA 3DSLA 2D1NA 5L79A 3K7NA 1SU3A 2OZRA 3MA2A 2FV9A 1QIAA 1Y8JA 2OVZA 3LMCA 1WNIA 1C3IA 1CQRA 1JKYA 2W0DA 4J4MA 1K7IA 3L0TA 1J7NA 2ERPA 4FXYP 1BQQM 3LUMA 1R55A 5D1UA 1MMPA 3BA0A 5I12A 2OW2A 2X3AA 4Q1LA 1GO7P 2JIHA 4AXQA 1IAGA 2USNA 4H84A 2X3BA 2E3XA 2DDFA 1PWUA 2OW9A 1ZVXA 1CGEA 1ZP5A 4H1QA 1XFZA 3RTSA 4A7BA 3DWBA 2OXUA 3F1AA 2W14A 3KEJA 3O64A 1XUDA 1BKCE 2OVXA 1CGFA 1I73A 1JJ9A 3I7GA 1DMTA 3KMCA 3LK8A 4ILWD 4FU4A 5D1SA 3TVCA 1YQYA 1G12A 4PKSA 1CIZA 1YP1A 3DPFA 1EAKA 1XFWA 3DL1A 2RJPA 2YUFA 1G4KA 4PKWA 4GR8A 1MNCA 5D1TA 1OO9A 5BOTA 1IABA 3I7IA 1UTZA 4GR3A 2JSDA 1BSWA 3DTEA 2OY2A 1Z3JA 3ZXHA 1HFSA 2W12A 1QJJA 4EFSA 3KWVC 2J0TA 2OI0A 3B2ZA 4WKIA 2MZIA 2Y6CA 3N2VA 2N8RA 4GQLA 3V96B 2X3CA 1JAOA 1IAEA 1K7QA 2MZHA 1L6JA 3E8RA 1GKCA 1SMPA 4H3XA 3P24A 1XFXA 3GBOA 2OW0A 1SRPA 1HOVA 2PJTA 3LGPA 1JAQA 1R1JA 1AKLA 1CGLA 1ATLA 1R1HA 1UEAA 1KUFA 3F18A 1I1IP 1I76A 3WV1A 1DTHA 3LE9A 3KMEA 2D1OA 4FVLA 3G42A 2MLRA 5BPAA 3HBVP 966CA 1CXVA 1SLNA 1OM7A 1C8TA 2DW2A 3F15A 2TCLA 3HDAP 2E2DA 1GE6A 1HFCA 2YB9A 2XS3A 1C7KA 4G0DA 1G05A 4JA1A 1OS2A 4ZR5A 5D3CA 5LABA 3LQBA 1OMJA 3DTIA 2A8HA 1XUCA 3OHOA 4H2EA 2YIGA 5B5PA 2DW1A 1R54A 3EDGA 3F19A 2K2GA 3TS4A 2JT6A 1KBCA 5I3MA 2OY4A 3EHYA 3K7LA 4H49A 3LQ0A 1OS9A 3ZUKA 1YCMA 2OXWA 5CZMA 3L0VA 1ASTA 2AYKA 3ZVSA 1OM6A 1O0TA 1BUDA 4XCTA 1IADA 2WO9A 1KUGA 1PWWA 1PWPA 1R1IA 2RJQA 4WF6A 1JK3A 3UVCA 2CKIA 1EB6A 3O2XA 1UTTA 3HDBA 1Y93A 3P1VA 3B8ZA 1D8FA 1BKCI 5D2BA 5I4OA 3KRYA 2KRJA 3WV3A 1PWQA 1MMBA 4H82A 3LEAA 2DW0A 4GF1A 4GUYA 3RTTA 2JNPA 1ZXCA 4DF9A 3HY7A 2Y6DA 1AYKA 3VTGA 4A3WA 3LJZA 4XM8A 1SLMA 3LJTA 3OHLA 4QKZA 3USNA 4WK7A 2OXZA 3LIRA 3LILA 1TVIA 1XAXA 1MMQA 2EROA 3AYUA 1GXDA 5I0LA 4JIJA 4DD8A 3EDHA 4JPAA 2AIGP 1BIWA 1D8MA 5I43A 3HYGA 3TSKA 4AYKA 1HTDA 2DDYA 1EUBA 3Q2HA 3HBUP 1BUVM 1YOUA 456CA 3LJGA 1JIZA 1GE5A 1USNA 3DTKA 1Q3AA 1UMTA 1ND1A 3ELMA 1B3DA 1ZXVA 1IACA 3F16A 1KUIA 3HB2P 1RMZA
chains in the Genus database with same CATH topology
1CAQA 4JP4A 2X7MA 1CK7A 2MZEA 2CLTA 1HV5A 4I03A 3B92A 3VI1A 2L0RA 1SATA 4GWNA 1RM8A 1FM1A 4H76A 1D5JA 1G9KA 1XFYA 1HY7A 1OM8A 2K9CA 3EWJA 3EDIA 1XURA 4IN9A 5CUHA 2JT5A 1H71P 2O3EA 4I35A 1FLSA 3Q2GA 4AUOA 2POJA 2J83A 2W13A 4CTHA 4IJOA 830CA 4R3VA 1BQOA 5B5OA 2W15A 1JH1A 4G9LA 5D7WA 2QPJA 4GR0A 5CXAA 1QIBA 3DPEA 4IUWA 1ROSA 1KUKA 1BZSA 5JMYA 3KEKA 3LUNA 4ON1A 3EHXA 4PKVA 1Y0VA 2I47A 2WO8A 2XS4A 1MMRA 2OW1A 4JQGA 1JANA 4L19A 4XM6A 4L6TA 2Z2DA 1B8YA 3KECA 3U1RA 1BKCA 1O0QA 1ZTQA 4L7AA 4HX3A 4AIGA 4PKQA 1G49A 3NX7A 1BM6A 4FXQA 3WV2A 2MLSA 1QJIA 3F17A 3TT4A 5I2ZA 1PWVA 5L7FA 3EDZA 1JIWP 3AYKA 1IAAA 1GO8P 1QICA 4WKEA 1S4BP 1KAPP 5BOYA 4HMAA 1A86A 1KUHA 5H8XA 1XFVA 2O36A 2WOAA 1AF0A 4PKTA 2ERQA 3KHIA 2SRTA 3G5CA 1A85A 1QUAA 1GE7A 2FV5A 3DNGA 1FBLA 3LKAA 4PKUA 4DPEA 4XBHA 1XFUA 2V4BA 1K7GA 1UMSA 1GKDA 4H30A 4L63A 4XM7A 4DV8A 1ZS0A 3AIGA 3N2UA 3HY9A 4GWMA 3SHIA 3CKIA 3LIKA 4PKRA 1D7XA 4WZVA 2HU6A 1JAPA 3DSLA 2D1NA 5L79A 3K7NA 1SU3A 2OZRA 3MA2A 2FV9A 1QIAA 1Y8JA 2OVZA 3LMCA 1WNIA 1C3IA 1CQRA 1JKYA 2W0DA 4J4MA 1K7IA 3L0TA 1J7NA 2ERPA 4FXYP 1BQQM 3LUMA 1R55A 5D1UA 1MMPA 3BA0A 5I12A 2OW2A 2X3AA 4Q1LA 1GO7P 2JIHA 4AXQA 1IAGA 2USNA 4H84A 2X3BA 2E3XA 2DDFA 1PWUA 2OW9A 1ZVXA 1CGEA 1ZP5A 4H1QA 1XFZA 3RTSA 4A7BA 3DWBA 2OXUA 3F1AA 2W14A 3KEJA 3O64A 1XUDA 1BKCE 2OVXA 1CGFA 1I73A 1JJ9A 3I7GA 1DMTA 3KMCA 3LK8A 4ILWD 4FU4A 5D1SA 3TVCA 1YQYA 1G12A 4PKSA 1CIZA 1YP1A 3DPFA 1EAKA 1XFWA 3DL1A 2RJPA 2YUFA 1G4KA 4PKWA 4GR8A 1MNCA 5D1TA 1OO9A 5BOTA 1IABA 3I7IA 1UTZA 4GR3A 2JSDA 1BSWA 3DTEA 2OY2A 1Z3JA 3ZXHA 1HFSA 2W12A 1QJJA 4EFSA 3KWVC 2J0TA 2OI0A 3B2ZA 4WKIA 2MZIA 2Y6CA 3N2VA 2N8RA 4GQLA 3V96B 2X3CA 1JAOA 1IAEA 1K7QA 2MZHA 1L6JA 3E8RA 1GKCA 1SMPA 4H3XA 3P24A 1XFXA 3GBOA 2OW0A 1SRPA 1HOVA 2PJTA 3LGPA 1JAQA 1R1JA 1AKLA 1CGLA 1ATLA 1R1HA 1UEAA 1KUFA 3F18A 1I1IP 1I76A 3WV1A 1DTHA 3LE9A 3KMEA 2D1OA 4FVLA 3G42A 2MLRA 5BPAA 3HBVP 966CA 1CXVA 1SLNA 1OM7A 1C8TA 2DW2A 3F15A 2TCLA 3HDAP 2E2DA 1GE6A 1HFCA 2YB9A 2XS3A 1C7KA 4G0DA 1G05A 4JA1A 1OS2A 4ZR5A 5D3CA 5LABA 3LQBA 1OMJA 3DTIA 2A8HA 1XUCA 3OHOA 4H2EA 2YIGA 5B5PA 2DW1A 1R54A 3EDGA 3F19A 2K2GA 3TS4A 2JT6A 1KBCA 5I3MA 2OY4A 3EHYA 3K7LA 4H49A 3LQ0A 1OS9A 3ZUKA 1YCMA 2OXWA 5CZMA 3L0VA 1ASTA 2AYKA 3ZVSA 1OM6A 1O0TA 1BUDA 4XCTA 1IADA 2WO9A 1KUGA 1PWWA 1PWPA 1R1IA 2RJQA 4WF6A 1JK3A 3UVCA 2CKIA 1EB6A 3O2XA 1UTTA 3HDBA 1Y93A 3P1VA 3B8ZA 1D8FA 1BKCI 5D2BA 5I4OA 3KRYA 2KRJA 3WV3A 1PWQA 1MMBA 4H82A 3LEAA 2DW0A 4GF1A 4GUYA 3RTTA 2JNPA 1ZXCA 4DF9A 3HY7A 2Y6DA 1AYKA 3VTGA 4A3WA 3LJZA 4XM8A 1SLMA 3LJTA 3OHLA 4QKZA 3USNA 4WK7A 2OXZA 3LIRA 3LILA 1MMQA 2EROA 3AYUA 1GXDA 5I0LA 4JIJA 4DD8A 3EDHA 4JPAA 2AIGP 1BIWA 1D8MA 5I43A 3HYGA 3TSKA 4AYKA 1HTDA 2DDYA 1EUBA 3Q2HA 3HBUP 1BUVM 1YOUA 456CA 3LJGA 1JIZA 1GE5A 1USNA 3DTKA 1Q3AA 1UMTA 1ND1A 3ELMA 1B3DA 1ZXVA 1IACA 3F16A 1KUIA 3HB2P 1RMZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CAQ A;  4JP4 A;  2X7M A;  1CK7 A;  2MZE A;  2CLT A;  1HV5 A;  4I03 A;  3B92 A;  3VI1 A;  2L0R A;  1SAT A;  4GWN A;  1RM8 A;  1FM1 A;  4H76 A;  1D5J A;  1G9K A;  1XFY A;  1HY7 A;  1OM8 A;  2K9C A;  3EWJ A;  3EDI A;  1XUR A;  4IN9 A;  5CUH A;  2JT5 A;  1H71 P;  2O3E A;  4I35 A;  1FLS A;  3Q2G A;  4AUO A;  2POJ A;  2J83 A;  2W13 A;  4CTH A;  4IJO A;  830C A;  4R3V A;  1BQO A;  5B5O A;  2W15 A;  1JH1 A;  4G9L A;  5D7W A;  2QPJ A;  4GR0 A;  5CXA A;  1QIB A;  3DPE A;  4IUW A;  1ROS A;  1KUK A;  1BZS A;  5JMY A;  3KEK A;  3LUN A;  4ON1 A;  3EHX A;  4PKV A;  1Y0V A;  2I47 A;  2WO8 A;  2XS4 A;  1MMR A;  2OW1 A;  4JQG A;  1JAN A;  4L19 A;  4XM6 A;  4L6T A;  2Z2D A;  1B8Y A;  3KEC A;  3U1R A;  1BKC A;  1O0Q A;  1ZTQ A;  4HX3 A;  4AIG A;  4PKQ A;  1G49 A;  3NX7 A;  1BM6 A;  4FXQ A;  3WV2 A;  2MLS A;  1QJI A;  3F17 A;  3TT4 A;  5I2Z A;  1PWV A;  5L7F A;  3EDZ A;  1JIW P;  3AYK A;  1IAA A;  1GO8 P;  1QIC A;  4WKE A;  1S4B P;  1KAP P;  5BOY A;  4HMA A;  1A86 A;  1KUH A;  5H8X A;  1XFV A;  2O36 A;  2WOA A;  1AF0 A;  4PKT A;  2ERQ A;  3KHI A;  2SRT A;  3G5C A;  1A85 A;  1QUA A;  1GE7 A;  2FV5 A;  3DNG A;  1FBL A;  3LKA A;  4PKU A;  4DPE A;  4XBH A;  1XFU A;  2V4B A;  1K7G A;  1UMS A;  1GKD A;  4H30 A;  4L63 A;  4XM7 A;  4DV8 A;  1ZS0 A;  3AIG A;  3N2U A;  3HY9 A;  4GWM A;  3SHI A;  3CKI A;  3LIK A;  4PKR A;  1D7X A;  4WZV A;  2HU6 A;  1JAP A;  3DSL A;  2D1N A;  5L79 A;  3K7N A;  1SU3 A;  2OZR A;  3MA2 A;  2FV9 A;  1QIA A;  1Y8J A;  2OVZ A;  3LMC A;  1WNI A;  1C3I A;  1CQR A;  1JKY A;  2W0D A;  4J4M A;  1K7I A;  3L0T A;  1J7N A;  2ERP A;  4FXY P;  1BQQ M;  3LUM A;  1R55 A;  5D1U A;  1MMP A;  3BA0 A;  5I12 A;  2OW2 A;  2X3A A;  4Q1L A;  1GO7 P;  2JIH A;  4AXQ A;  1IAG A;  2USN A;  4H84 A;  2X3B A;  2E3X A;  2DDF A;  1PWU A;  2OW9 A;  1ZVX A;  1CGE A;  1ZP5 A;  4H1Q A;  1XFZ A;  3RTS A;  4A7B A;  3DWB A;  2OXU A;  3F1A A;  2W14 A;  3KEJ A;  3O64 A;  1XUD A;  1BKC E;  2OVX A;  1CGF A;  1I73 A;  1JJ9 A;  3I7G A;  1DMT A;  3KMC A;  3LK8 A;  4ILW D;  4FU4 A;  5D1S A;  3TVC A;  1YQY A;  1G12 A;  4PKS A;  1CIZ A;  1YP1 A;  3DPF A;  1EAK A;  1XFW A;  3DL1 A;  2RJP A;  1G4K A;  4PKW A;  4GR8 A;  1MNC A;  5D1T A;  1OO9 A;  5BOT A;  1IAB A;  3I7I A;  1UTZ A;  4GR3 A;  2JSD A;  1BSW A;  2OY2 A;  1Z3J A;  3ZXH A;  1HFS A;  2W12 A;  1QJJ A;  4EFS A;  3KWV C;  2J0T A;  2OI0 A;  3B2Z A;  4WKI A;  2MZI A;  2Y6C A;  3N2V A;  2N8R A;  4GQL A;  3V96 B;  2X3C A;  1JAO A;  1IAE A;  1K7Q A;  2MZH A;  1L6J A;  3E8R A;  1GKC A;  1SMP A;  4H3X A;  3P24 A;  1XFX A;  3GBO A;  2OW0 A;  1SRP A;  1HOV A;  2PJT A;  3LGP A;  1JAQ A;  1R1J A;  1AKL A;  1CGL A;  1ATL A;  1R1H A;  1UEA A;  1KUF A;  3F18 A;  1I1I P;  1I76 A;  3WV1 A;  1DTH A;  3LE9 A;  3KME A;  2D1O A;  4FVL A;  3G42 A;  2MLR A;  5BPA A;  3HBV P;  966C A;  1CXV A;  1SLN A;  1OM7 A;  1C8T A;  2DW2 A;  3F15 A;  2TCL A;  3HDA P;  2E2D A;  1GE6 A;  1HFC A;  2YB9 A;  2XS3 A;  1C7K A;  4G0D A;  1G05 A;  4JA1 A;  1OS2 A;  4ZR5 A;  5D3C A;  5LAB A;  3LQB A;  1OMJ A;  2A8H A;  1XUC A;  3OHO A;  4H2E A;  2YIG A;  5B5P A;  2DW1 A;  1R54 A;  3EDG A;  3F19 A;  2K2G A;  3TS4 A;  2JT6 A;  1KBC A;  5I3M A;  2OY4 A;  3EHY A;  3K7L A;  4H49 A;  3LQ0 A;  1OS9 A;  3ZUK A;  1YCM A;  2OXW A;  5CZM A;  3L0V A;  1AST A;  2AYK A;  3ZVS A;  1OM6 A;  1O0T A;  1BUD A;  4XCT A;  1IAD A;  2WO9 A;  1KUG A;  1PWW A;  1PWP A;  1R1I A;  2RJQ A;  4WF6 A;  1JK3 A;  3UVC A;  2CKI A;  1EB6 A;  3O2X A;  1UTT A;  3HDB A;  1Y93 A;  3P1V A;  3B8Z A;  1D8F A;  1BKC I;  5D2B A;  5I4O A;  3KRY A;  2KRJ A;  3WV3 A;  1PWQ A;  1MMB A;  4H82 A;  3LEA A;  2DW0 A;  4GF1 A;  4GUY A;  3RTT A;  2JNP A;  1ZXC A;  4DF9 A;  3HY7 A;  2Y6D A;  1AYK A;  3VTG A;  4A3W A;  3LJZ A;  4XM8 A;  1SLM A;  3LJT A;  3OHL A;  4QKZ A;  3USN A;  4WK7 A;  2OXZ A;  3LIR A;  3LIL A;  1MMQ A;  2ERO A;  3AYU A;  1GXD A;  5I0L A;  4JIJ A;  4DD8 A;  3EDH A;  4JPA A;  2AIG P;  1BIW A;  1D8M A;  5I43 A;  3HYG A;  3TSK A;  4AYK A;  1HTD A;  2DDY A;  1EUB A;  3Q2H A;  3HBU P;  1BUV M;  1YOU A;  456C A;  3LJG A;  1JIZ A;  1GE5 A;  1USN A;  1Q3A A;  1UMT A;  1ND1 A;  3ELM A;  1B3D A;  1ZXV A;  1IAC A;  3F16 A;  1KUI A;  3HB2 P;  1RMZ A; 
#chains in the Genus database with same CATH topology
 1CAQ A;  4JP4 A;  2X7M A;  1CK7 A;  2MZE A;  2CLT A;  1HV5 A;  4I03 A;  3B92 A;  3VI1 A;  2L0R A;  1SAT A;  4GWN A;  1RM8 A;  1FM1 A;  4H76 A;  1XM5 A;  1D5J A;  1G9K A;  1XFY A;  1HY7 A;  1OM8 A;  2K9C A;  3EWJ A;  3EDI A;  1XUR A;  4IN9 A;  5CUH A;  2JT5 A;  1H71 P;  2O3E A;  4I35 A;  1FLS A;  3Q2G A;  4AUO A;  2POJ A;  2J83 A;  2W13 A;  4CTH A;  4IJO A;  830C A;  4R3V A;  1BQO A;  5B5O A;  2W15 A;  1JH1 A;  4G9L A;  5D7W A;  2QPJ A;  4GR0 A;  5CXA A;  1QIB A;  3DPE A;  4IUW A;  1ROS A;  1KUK A;  1BZS A;  5JMY A;  3KEK A;  3LUN A;  4ON1 A;  3EHX A;  4PKV A;  1Y0V A;  2I47 A;  2WO8 A;  2XS4 A;  1MMR A;  2OW1 A;  4JQG A;  1JAN A;  4L19 A;  4XM6 A;  4L6T A;  2Z2D A;  1B8Y A;  3KEC A;  3U1R A;  1BKC A;  1O0Q A;  1ZTQ A;  4L7A A;  4HX3 A;  4AIG A;  4PKQ A;  1G49 A;  3NX7 A;  1BM6 A;  4FXQ A;  3WV2 A;  2MLS A;  1QJI A;  3F17 A;  3TT4 A;  5I2Z A;  1PWV A;  1OZ9 A;  5L7F A;  3EDZ A;  1JIW P;  3AYK A;  1IAA A;  1GO8 P;  1QIC A;  4WKE A;  1S4B P;  1KAP P;  5BOY A;  4HMA A;  1A86 A;  1KUH A;  5H8X A;  1XFV A;  2O36 A;  2WOA A;  1AF0 A;  4PKT A;  2ERQ A;  3KHI A;  2SRT A;  3G5C A;  1A85 A;  1QUA A;  1GE7 A;  2FV5 A;  3DNG A;  1FBL A;  3LKA A;  4PKU A;  4DPE A;  4XBH A;  1XFU A;  2V4B A;  1K7G A;  1UMS A;  1GKD A;  4H30 A;  4L63 A;  4XM7 A;  4DV8 A;  1ZS0 A;  3AIG A;  3N2U A;  3HY9 A;  4GWM A;  3SHI A;  3CKI A;  3LIK A;  4PKR A;  1D7X A;  4WZV A;  2HU6 A;  1JAP A;  3DSL A;  2D1N A;  5L79 A;  3K7N A;  1SU3 A;  2OZR A;  3MA2 A;  2FV9 A;  1QIA A;  1Y8J A;  2OVZ A;  3LMC A;  1WNI A;  1C3I A;  1CQR A;  1JKY A;  2W0D A;  4J4M A;  1K7I A;  3L0T A;  1J7N A;  2ERP A;  4FXY P;  1BQQ M;  3LUM A;  1R55 A;  5D1U A;  1MMP A;  3BA0 A;  5I12 A;  2OW2 A;  2X3A A;  4Q1L A;  1GO7 P;  2JIH A;  4AXQ A;  1IAG A;  2USN A;  4H84 A;  2X3B A;  2E3X A;  2DDF A;  1PWU A;  2OW9 A;  1ZVX A;  1CGE A;  1ZP5 A;  4H1Q A;  1XFZ A;  3RTS A;  4A7B A;  3DWB A;  2OXU A;  3F1A A;  2W14 A;  3KEJ A;  3O64 A;  1XUD A;  1BKC E;  2OVX A;  1CGF A;  1I73 A;  1JJ9 A;  3I7G A;  1DMT A;  3KMC A;  3LK8 A;  4ILW D;  4FU4 A;  5D1S A;  3TVC A;  1YQY A;  1G12 A;  4PKS A;  1CIZ A;  1YP1 A;  3DPF A;  1EAK A;  1XFW A;  3DL1 A;  2RJP A;  2YUF A;  1G4K A;  4PKW A;  4GR8 A;  1MNC A;  5D1T A;  1OO9 A;  5BOT A;  1IAB A;  3I7I A;  1UTZ A;  4GR3 A;  2JSD A;  1BSW A;  3DTE A;  2OY2 A;  1Z3J A;  3ZXH A;  1HFS A;  2W12 A;  1QJJ A;  4EFS A;  3KWV C;  2J0T A;  2OI0 A;  3B2Z A;  4WKI A;  2MZI A;  2Y6C A;  3N2V A;  2N8R A;  4GQL A;  3V96 B;  2X3C A;  1JAO A;  1IAE A;  1K7Q A;  2MZH A;  1L6J A;  3E8R A;  1GKC A;  1SMP A;  4H3X A;  3P24 A;  1XFX A;  3GBO A;  2OW0 A;  1SRP A;  1HOV A;  2PJT A;  3LGP A;  1JAQ A;  1R1J A;  1AKL A;  1CGL A;  1ATL A;  1R1H A;  1UEA A;  1KUF A;  3F18 A;  1I1I P;  1I76 A;  3WV1 A;  1DTH A;  3LE9 A;  3KME A;  2D1O A;  4FVL A;  3G42 A;  2MLR A;  5BPA A;  3HBV P;  966C A;  1CXV A;  1SLN A;  1OM7 A;  1C8T A;  2DW2 A;  3F15 A;  2TCL A;  3HDA P;  2E2D A;  1GE6 A;  1HFC A;  2YB9 A;  2XS3 A;  1C7K A;  4G0D A;  1G05 A;  4JA1 A;  1OS2 A;  4ZR5 A;  5D3C A;  5LAB A;  3LQB A;  1OMJ A;  3DTI A;  2A8H A;  1XUC A;  3OHO A;  4H2E A;  2YIG A;  5B5P A;  2DW1 A;  1R54 A;  3EDG A;  3F19 A;  2K2G A;  3TS4 A;  2JT6 A;  1KBC A;  5I3M A;  2OY4 A;  3EHY A;  3K7L A;  4H49 A;  3LQ0 A;  1OS9 A;  3ZUK A;  1YCM A;  2OXW A;  5CZM A;  3L0V A;  1AST A;  2AYK A;  3ZVS A;  1OM6 A;  1O0T A;  1BUD A;  4XCT A;  1IAD A;  2WO9 A;  1KUG A;  1PWW A;  1PWP A;  1R1I A;  2RJQ A;  4WF6 A;  1JK3 A;  3UVC A;  2CKI A;  1EB6 A;  3O2X A;  1UTT A;  3HDB A;  1Y93 A;  3P1V A;  3B8Z A;  1D8F A;  1BKC I;  5D2B A;  5I4O A;  3KRY A;  2KRJ A;  3WV3 A;  1PWQ A;  1MMB A;  4H82 A;  3LEA A;  2DW0 A;  4GF1 A;  4GUY A;  3RTT A;  2JNP A;  1ZXC A;  4DF9 A;  3HY7 A;  2Y6D A;  1AYK A;  3VTG A;  4A3W A;  3LJZ A;  4XM8 A;  1SLM A;  3LJT A;  3OHL A;  4QKZ A;  3USN A;  4WK7 A;  2OXZ A;  3LIR A;  3LIL A;  1TVI A;  1XAX A;  1MMQ A;  2ERO A;  3AYU A;  1GXD A;  5I0L A;  4JIJ A;  4DD8 A;  3EDH A;  4JPA A;  2AIG P;  1BIW A;  1D8M A;  5I43 A;  3HYG A;  3TSK A;  4AYK A;  1HTD A;  2DDY A;  1EUB A;  3Q2H A;  3HBU P;  1BUV M;  1YOU A;  456C A;  3LJG A;  1JIZ A;  1GE5 A;  1USN A;  3DTK A;  1Q3A A;  1UMT A;  1ND1 A;  3ELM A;  1B3D A;  1ZXV A;  1IAC A;  3F16 A;  1KUI A;  3HB2 P;  1RMZ A; 
#chains in the Genus database with same CATH homology
 1CAQ A;  4JP4 A;  2X7M A;  1CK7 A;  2MZE A;  2CLT A;  1HV5 A;  4I03 A;  3B92 A;  3VI1 A;  2L0R A;  1SAT A;  4GWN A;  1RM8 A;  1FM1 A;  4H76 A;  1D5J A;  1G9K A;  1XFY A;  1HY7 A;  1OM8 A;  2K9C A;  3EWJ A;  3EDI A;  1XUR A;  4IN9 A;  5CUH A;  2JT5 A;  1H71 P;  2O3E A;  4I35 A;  1FLS A;  3Q2G A;  4AUO A;  2POJ A;  2J83 A;  2W13 A;  4CTH A;  4IJO A;  830C A;  4R3V A;  1BQO A;  5B5O A;  2W15 A;  1JH1 A;  4G9L A;  5D7W A;  2QPJ A;  4GR0 A;  5CXA A;  1QIB A;  3DPE A;  4IUW A;  1ROS A;  1KUK A;  1BZS A;  5JMY A;  3KEK A;  3LUN A;  4ON1 A;  3EHX A;  4PKV A;  1Y0V A;  2I47 A;  2WO8 A;  2XS4 A;  1MMR A;  2OW1 A;  4JQG A;  1JAN A;  4L19 A;  4XM6 A;  4L6T A;  2Z2D A;  1B8Y A;  3KEC A;  3U1R A;  1BKC A;  1O0Q A;  1ZTQ A;  4L7A A;  4HX3 A;  4AIG A;  4PKQ A;  1G49 A;  3NX7 A;  1BM6 A;  4FXQ A;  3WV2 A;  2MLS A;  1QJI A;  3F17 A;  3TT4 A;  5I2Z A;  1PWV A;  5L7F A;  3EDZ A;  1JIW P;  3AYK A;  1IAA A;  1GO8 P;  1QIC A;  4WKE A;  1S4B P;  1KAP P;  5BOY A;  4HMA A;  1A86 A;  1KUH A;  5H8X A;  1XFV A;  2O36 A;  2WOA A;  1AF0 A;  4PKT A;  2ERQ A;  3KHI A;  2SRT A;  3G5C A;  1A85 A;  1QUA A;  1GE7 A;  2FV5 A;  3DNG A;  1FBL A;  3LKA A;  4PKU A;  4DPE A;  4XBH A;  1XFU A;  2V4B A;  1K7G A;  1UMS A;  1GKD A;  4H30 A;  4L63 A;  4XM7 A;  4DV8 A;  1ZS0 A;  3AIG A;  3N2U A;  3HY9 A;  4GWM A;  3SHI A;  3CKI A;  3LIK A;  4PKR A;  1D7X A;  4WZV A;  2HU6 A;  1JAP A;  3DSL A;  2D1N A;  5L79 A;  3K7N A;  1SU3 A;  2OZR A;  3MA2 A;  2FV9 A;  1QIA A;  1Y8J A;  2OVZ A;  3LMC A;  1WNI A;  1C3I A;  1CQR A;  1JKY A;  2W0D A;  4J4M A;  1K7I A;  3L0T A;  1J7N A;  2ERP A;  4FXY P;  1BQQ M;  3LUM A;  1R55 A;  5D1U A;  1MMP A;  3BA0 A;  5I12 A;  2OW2 A;  2X3A A;  4Q1L A;  1GO7 P;  2JIH A;  4AXQ A;  1IAG A;  2USN A;  4H84 A;  2X3B A;  2E3X A;  2DDF A;  1PWU A;  2OW9 A;  1ZVX A;  1CGE A;  1ZP5 A;  4H1Q A;  1XFZ A;  3RTS A;  4A7B A;  3DWB A;  2OXU A;  3F1A A;  2W14 A;  3KEJ A;  3O64 A;  1XUD A;  1BKC E;  2OVX A;  1CGF A;  1I73 A;  1JJ9 A;  3I7G A;  1DMT A;  3KMC A;  3LK8 A;  4ILW D;  4FU4 A;  5D1S A;  3TVC A;  1YQY A;  1G12 A;  4PKS A;  1CIZ A;  1YP1 A;  3DPF A;  1EAK A;  1XFW A;  3DL1 A;  2RJP A;  2YUF A;  1G4K A;  4PKW A;  4GR8 A;  1MNC A;  5D1T A;  1OO9 A;  5BOT A;  1IAB A;  3I7I A;  1UTZ A;  4GR3 A;  2JSD A;  1BSW A;  3DTE A;  2OY2 A;  1Z3J A;  3ZXH A;  1HFS A;  2W12 A;  1QJJ A;  4EFS A;  3KWV C;  2J0T A;  2OI0 A;  3B2Z A;  4WKI A;  2MZI A;  2Y6C A;  3N2V A;  2N8R A;  4GQL A;  3V96 B;  2X3C A;  1JAO A;  1IAE A;  1K7Q A;  2MZH A;  1L6J A;  3E8R A;  1GKC A;  1SMP A;  4H3X A;  3P24 A;  1XFX A;  3GBO A;  2OW0 A;  1SRP A;  1HOV A;  2PJT A;  3LGP A;  1JAQ A;  1R1J A;  1AKL A;  1CGL A;  1ATL A;  1R1H A;  1UEA A;  1KUF A;  3F18 A;  1I1I P;  1I76 A;  3WV1 A;  1DTH A;  3LE9 A;  3KME A;  2D1O A;  4FVL A;  3G42 A;  2MLR A;  5BPA A;  3HBV P;  966C A;  1CXV A;  1SLN A;  1OM7 A;  1C8T A;  2DW2 A;  3F15 A;  2TCL A;  3HDA P;  2E2D A;  1GE6 A;  1HFC A;  2YB9 A;  2XS3 A;  1C7K A;  4G0D A;  1G05 A;  4JA1 A;  1OS2 A;  4ZR5 A;  5D3C A;  5LAB A;  3LQB A;  1OMJ A;  3DTI A;  2A8H A;  1XUC A;  3OHO A;  4H2E A;  2YIG A;  5B5P A;  2DW1 A;  1R54 A;  3EDG A;  3F19 A;  2K2G A;  3TS4 A;  2JT6 A;  1KBC A;  5I3M A;  2OY4 A;  3EHY A;  3K7L A;  4H49 A;  3LQ0 A;  1OS9 A;  3ZUK A;  1YCM A;  2OXW A;  5CZM A;  3L0V A;  1AST A;  2AYK A;  3ZVS A;  1OM6 A;  1O0T A;  1BUD A;  4XCT A;  1IAD A;  2WO9 A;  1KUG A;  1PWW A;  1PWP A;  1R1I A;  2RJQ A;  4WF6 A;  1JK3 A;  3UVC A;  2CKI A;  1EB6 A;  3O2X A;  1UTT A;  3HDB A;  1Y93 A;  3P1V A;  3B8Z A;  1D8F A;  1BKC I;  5D2B A;  5I4O A;  3KRY A;  2KRJ A;  3WV3 A;  1PWQ A;  1MMB A;  4H82 A;  3LEA A;  2DW0 A;  4GF1 A;  4GUY A;  3RTT A;  2JNP A;  1ZXC A;  4DF9 A;  3HY7 A;  2Y6D A;  1AYK A;  3VTG A;  4A3W A;  3LJZ A;  4XM8 A;  1SLM A;  3LJT A;  3OHL A;  4QKZ A;  3USN A;  4WK7 A;  2OXZ A;  3LIR A;  3LIL A;  1MMQ A;  2ERO A;  3AYU A;  1GXD A;  5I0L A;  4JIJ A;  4DD8 A;  3EDH A;  4JPA A;  2AIG P;  1BIW A;  1D8M A;  5I43 A;  3HYG A;  3TSK A;  4AYK A;  1HTD A;  2DDY A;  1EUB A;  3Q2H A;  3HBU P;  1BUV M;  1YOU A;  456C A;  3LJG A;  1JIZ A;  1GE5 A;  1USN A;  3DTK A;  1Q3A A;  1UMT A;  1ND1 A;  3ELM A;  1B3D A;  1ZXV A;  1IAC A;  3F16 A;  1KUI A;  3HB2 P;  1RMZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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