2DDFA

Crystal structure of tace in complex with tapi-2
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
257
structure length
253
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords ADAM 17
publication title Stabilization of the autoproteolysis of TNF-alpha converting enzyme (TACE) results in a novel crystal form suitable for structure-based drug design studies.
pubmed doi rcsb
source organism Homo sapiens
total genus 82
structure length 253
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2006-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2ddfA00
2DW2A 4AXQA 4A7BA 2OW9A 3F18A 1B8YA 3NX7A 1ROSA 1Y93A 2JT6A 1D8MA 1H71P 1HTDA 1D5JA 1K7QA 3L0VA 3LILA 1IAGA 2OW0A 4Q1LA 4JPAA 1ZXCA 3WV3A 3LE9A 1K7IA 5D7WA 1GE5A 4GR3A 1O0TA 2K9CA 1FM1A 1BQQM 1BKCA 1PWWA 5BOTA 1Z3JA 1S4BP 1KUHA 5L7FA 4G9LA 4H84A 3B2ZA 3EDGA 1KBCA 1QJIA 1QUAA 1AF0A 3G42A 4ILWD 4WK7A 1MMBA 4PKWA 2CKIA 1EAKA 3AIGA 1JKYA 3ZUKA 2J0TA 3ELMA 1BM6A 1IAEA 5I43A 3TT4A 1A86A 1IAAA 2WO9A 5B5OA 3HBVP 2WOAA 5L79A 3AYKA 966CA 2MLRA 2RJPA 4R3VA 3RTTA 2X3CA 1R1JA 1HY7A 2SRTA 2K2GA 2AIGP 1XFZA 1XURA 1I73A 1EB6A 3V96B 3OHOA 1BIWA 4WZVA 3LJGA 4PKUA 1OO9A 2HU6A 4XM8A 4IJOA 1MMRA 2DW1A 1GO8P 3EDHA 3DSLA 4GQLA 3GBOA 5LABA 4JP4A 1FLSA 3F17A 3OHLA 4H82A 1JIWP 1YCMA 4DPEA 1BUVM 2I47A 5D1SA 2POJA 4DV8A 1IACA 1MMQA 3TVCA 830CA 1GXDA 2DDYA 1OS2A 4H30A 4PKRA 5D1UA 1CXVA 2KRJA 1D8FA 2EROA 2OXWA 1AKLA 1IABA 3LJZA 1GE7A 1QICA 2X3BA 3HY7A 3DNGA 1CK7A 4ZR5A 1HFCA 3TSKA 1C8TA 1O0QA 4GWNA 3HY9A 5I4OA 3DWBA 1ZVXA 3F16A 1G05A 1XFUA 3F1AA 4H1QA 3MA2A 5JMYA 2J83A 1G4KA 1SMPA 4XM7A 1KUKA 1KAPP 3I7IA 1JJ9A 3VTGA 1HFSA 2XS4A 3VI1A 3KEJA 4L6TA 1JAPA 2JNPA 4PKVA 3O64A 1G12A 3I7GA 1ZXVA 1GO7P 4GF1A 1AYKA 1QJJA 1SLMA 1QIAA 1OS9A 3Q2HA 2TCLA 3ZXHA 2DDFA 4XCTA 3HDAP 3EDZA 3CKIA 1I1IP 5D3CA 1XUDA 3EHXA 3O2XA 2JSDA 1MMPA 3RTSA 1WNIA 2O36A 4XBHA 2MLSA 1C3IA 3LIRA 1ASTA 1BSWA 5D2BA 3UVCA 1ND1A 1FBLA 1OM7A 2W12A 3N2UA 1JK3A 3LQ0A 4AYKA 4L63A 1L6JA 2XS3A 2ERQA 1R54A 1HV5A 1R55A 4HX3A 1ATLA 3EHYA 3LUNA 1I76A 2OZRA 3KHIA 1BKCI 1G9KA 4QKZA 4GR8A 2FV5A 4HMAA 2QPJA 3DL1A 2YIGA 4WF6A 2A8HA 1DMTA 4AUOA 1GKCA 1OM8A 1XFWA 2AYKA 5CXAA 2YB9A 3EDIA 1CIZA 4G0DA 1PWPA 5BPAA 5I3MA 1R1IA 3LJTA 2W13A 1JANA 2OY4A 3LGPA 2MZIA 3BA0A 2WO8A 1SRPA 1CQRA 3KRYA 1C7KA 1CAQA 1RMZA 4GUYA 5D1TA 1QIBA 3SHIA 2MZEA 1A85A 3WV1A 3KMCA 4PKSA 1KUGA 1UEAA 2OW1A 2W0DA 2ERPA 3F19A 3N2VA 4FXYP 1SLNA 2E2DA 5CUHA 1Y8JA 4JA1A 2OW2A 4FVLA 3K7NA 1UTZA 3LIKA 3B92A 1G49A 1RM8A 2X7MA 2OVZA 3HYGA 2CLTA 2PJTA 2JIHA 1JIZA 3EWJA 3P1VA 3LKAA 5I2ZA 2Y6CA 4XM6A 1BQOA 1PWQA 2OY2A 1KUFA 2Z2DA 1J7NA 3P24A 4H2EA 1BUDA 1OM6A 3L0TA 1SU3A 2X3AA 1BKCE 2L0RA 5B5PA 4JQGA 1DTHA 3KECA 1ZTQA 2V4BA 4H3XA 4EFSA 1CGLA 3F15A 4JIJA 3KMEA 3Q2GA 2D1OA 1GE6A 1ZP5A 2MZHA 1PWVA 4DF9A 4IUWA 4PKTA 2RJQA 3DPEA 1XUCA 4ON1A 2N8RA 4AIGA 3G5CA 1CGEA 3HBUP 1JH1A 3TS4A 5I12A 1JAQA 3B8ZA 3AYUA 4I03A 1PWUA 5H8XA 1YOUA 3LK8A 1MNCA 2FV9A 1XFVA 1Q3AA 3WV2A 2OVXA 3LEAA 1Y0VA 1UMTA 2E3XA 1XFYA 3K7LA 2D1NA 4J4MA 1KUIA 1YQYA 2USNA 4GWMA 1UMSA 3LMCA 3KEKA 3U1RA 3HB2P 456CA 3DPFA 3USNA 4FXQA 1IADA 1R1HA 3ZVSA 2W15A 4IN9A 4PKQA 4CTHA 4L19A 3LQBA 4H49A 1BZSA 3E8RA 4A3WA 2Y6DA 1B3DA 3KWVC 4GR0A 1SATA 1K7GA 1CGFA 4H76A 2OXZA 4I35A 4FU4A 2O3EA 1USNA 5BOYA 1HOVA 3HDBA 1GKDA 1OMJA 1EUBA 1ZS0A 4WKIA 2OXUA 5CZMA 2W14A 4WKEA 5I0LA 1YP1A 1D7XA 1UTTA 2JT5A 1JAOA 2OI0A 4DD8A 3LUMA 2DW0A 1XFXA
chains in the Genus database with same CATH superfamily
2DW2A 4AXQA 4A7BA 2OW9A 3F18A 1B8YA 3NX7A 1ROSA 1Y93A 2JT6A 1D8MA 1H71P 1HTDA 1D5JA 1K7QA 3L0VA 3LILA 1IAGA 2OW0A 4Q1LA 4JPAA 1ZXCA 3WV3A 3LE9A 1K7IA 5D7WA 1GE5A 4GR3A 1O0TA 2K9CA 4L7AA 1FM1A 1BQQM 1BKCA 1PWWA 5BOTA 1Z3JA 1S4BP 1KUHA 5L7FA 4G9LA 4H84A 3B2ZA 3EDGA 1KBCA 1QJIA 1QUAA 1AF0A 3G42A 4ILWD 4WK7A 1MMBA 4PKWA 2CKIA 1EAKA 3AIGA 1JKYA 3ZUKA 2J0TA 3ELMA 1BM6A 1IAEA 5I43A 3TT4A 1A86A 1IAAA 2WO9A 5B5OA 3HBVP 2WOAA 5L79A 3AYKA 966CA 2MLRA 2RJPA 4R3VA 3RTTA 2X3CA 1R1JA 1HY7A 2SRTA 2K2GA 2AIGP 1XFZA 1XURA 1I73A 1EB6A 3V96B 3OHOA 1BIWA 4WZVA 3LJGA 4PKUA 1OO9A 2HU6A 4XM8A 4IJOA 1MMRA 2DW1A 1GO8P 3EDHA 3DSLA 4GQLA 3GBOA 5LABA 4JP4A 1FLSA 3F17A 3OHLA 4H82A 3DTEA 1JIWP 1YCMA 4DPEA 1BUVM 2I47A 5D1SA 2POJA 4DV8A 1IACA 1MMQA 3TVCA 830CA 1GXDA 2DDYA 1OS2A 4H30A 4PKRA 5D1UA 1CXVA 2KRJA 1D8FA 2YUFA 2EROA 2OXWA 1AKLA 1IABA 3LJZA 1GE7A 1QICA 2X3BA 3HY7A 3DNGA 1CK7A 4ZR5A 1HFCA 3TSKA 1C8TA 1O0QA 4GWNA 3HY9A 5I4OA 3DWBA 1ZVXA 3F16A 1G05A 1XFUA 3F1AA 4H1QA 3MA2A 5JMYA 2J83A 1G4KA 1SMPA 4XM7A 1KUKA 1KAPP 3I7IA 1JJ9A 3VTGA 1HFSA 2XS4A 3VI1A 3KEJA 4L6TA 1JAPA 2JNPA 4PKVA 3O64A 1G12A 3I7GA 1ZXVA 1GO7P 4GF1A 1AYKA 1QJJA 1SLMA 1QIAA 1OS9A 3Q2HA 2TCLA 3ZXHA 2DDFA 4XCTA 3HDAP 3EDZA 3CKIA 1I1IP 5D3CA 1XUDA 3EHXA 3O2XA 2JSDA 1MMPA 3RTSA 1WNIA 2O36A 4XBHA 2MLSA 1C3IA 3LIRA 1ASTA 1BSWA 5D2BA 3UVCA 1ND1A 1FBLA 1OM7A 2W12A 3N2UA 1JK3A 3LQ0A 4AYKA 4L63A 1L6JA 2XS3A 2ERQA 1R54A 1HV5A 1R55A 4HX3A 1ATLA 3EHYA 3LUNA 1I76A 2OZRA 3KHIA 1BKCI 1G9KA 4QKZA 4GR8A 2FV5A 4HMAA 2QPJA 3DL1A 2YIGA 4WF6A 2A8HA 1DMTA 4AUOA 1GKCA 1OM8A 1XFWA 2AYKA 5CXAA 2YB9A 3EDIA 1CIZA 4G0DA 1OZ9A 1PWPA 5BPAA 5I3MA 1R1IA 3LJTA 2W13A 1JANA 2OY4A 3LGPA 2MZIA 3BA0A 1XAXA 2WO8A 1SRPA 1CQRA 3KRYA 1C7KA 1CAQA 1RMZA 4GUYA 5D1TA 1QIBA 3SHIA 2MZEA 1A85A 3WV1A 3KMCA 4PKSA 1KUGA 1UEAA 2OW1A 2W0DA 2ERPA 3F19A 3N2VA 4FXYP 1SLNA 2E2DA 5CUHA 1Y8JA 4JA1A 2OW2A 4FVLA 3K7NA 1UTZA 3LIKA 3B92A 1G49A 1RM8A 2X7MA 2OVZA 3HYGA 2CLTA 2PJTA 2JIHA 1JIZA 3EWJA 3P1VA 3LKAA 5I2ZA 1XM5A 2Y6CA 4XM6A 1BQOA 1PWQA 2OY2A 1KUFA 2Z2DA 1J7NA 3P24A 4H2EA 1BUDA 1OM6A 3L0TA 1SU3A 2X3AA 1BKCE 2L0RA 5B5PA 4JQGA 1DTHA 3KECA 1ZTQA 2V4BA 4H3XA 4EFSA 1CGLA 3F15A 3DTIA 4JIJA 3KMEA 3Q2GA 2D1OA 1GE6A 1ZP5A 2MZHA 1PWVA 4DF9A 4IUWA 4PKTA 2RJQA 3DPEA 1XUCA 4ON1A 2N8RA 4AIGA 3G5CA 1CGEA 3HBUP 1JH1A 3TS4A 5I12A 1JAQA 3B8ZA 3AYUA 4I03A 1PWUA 5H8XA 1YOUA 3LK8A 1MNCA 2FV9A 1XFVA 1Q3AA 3WV2A 2OVXA 3LEAA 1Y0VA 1UMTA 2E3XA 1XFYA 3K7LA 2D1NA 4J4MA 1KUIA 1YQYA 2USNA 4GWMA 1UMSA 3LMCA 3KEKA 3U1RA 3HB2P 456CA 3DPFA 3USNA 4FXQA 1IADA 1R1HA 3ZVSA 2W15A 4IN9A 4PKQA 4CTHA 4L19A 1TVIA 3LQBA 4H49A 1BZSA 3E8RA 4A3WA 2Y6DA 1B3DA 3KWVC 4GR0A 1SATA 1K7GA 1CGFA 4H76A 2OXZA 3DTKA 4I35A 4FU4A 2O3EA 1USNA 5BOYA 1HOVA 3HDBA 1GKDA 1OMJA 1EUBA 1ZS0A 4WKIA 2OXUA 5CZMA 2W14A 4WKEA 5I0LA 1YP1A 1D7XA 1UTTA 2JT5A 1JAOA 2OI0A 4DD8A 3LUMA 2DW0A 1XFXA
chains in the Genus database with same CATH topology
2DW2A 4AXQA 4A7BA 2OW9A 3F18A 1B8YA 3NX7A 1ROSA 1Y93A 2JT6A 1D8MA 1H71P 1HTDA 1D5JA 1K7QA 3L0VA 3LILA 1IAGA 2OW0A 4Q1LA 4JPAA 1ZXCA 3WV3A 3LE9A 1K7IA 5D7WA 1GE5A 4GR3A 1O0TA 2K9CA 4L7AA 1FM1A 1BQQM 1BKCA 1PWWA 5BOTA 1Z3JA 1S4BP 1KUHA 5L7FA 4G9LA 4H84A 3B2ZA 3EDGA 1KBCA 1QJIA 1QUAA 1AF0A 3G42A 4ILWD 4WK7A 1MMBA 4PKWA 2CKIA 1EAKA 3AIGA 1JKYA 3ZUKA 2J0TA 3ELMA 1BM6A 1IAEA 5I43A 3TT4A 1A86A 1IAAA 2WO9A 5B5OA 3HBVP 2WOAA 5L79A 3AYKA 966CA 2MLRA 2RJPA 4R3VA 3RTTA 2X3CA 1R1JA 1HY7A 2SRTA 2K2GA 2AIGP 1XFZA 1XURA 1I73A 1EB6A 3V96B 3OHOA 1BIWA 4WZVA 3LJGA 4PKUA 1OO9A 2HU6A 4XM8A 4IJOA 1MMRA 2DW1A 1GO8P 3EDHA 3DSLA 4GQLA 3GBOA 5LABA 4JP4A 1FLSA 3F17A 3OHLA 4H82A 3DTEA 1JIWP 1YCMA 4DPEA 1BUVM 2I47A 5D1SA 2POJA 4DV8A 1IACA 1MMQA 3TVCA 830CA 1GXDA 2DDYA 1OS2A 4H30A 4PKRA 5D1UA 1CXVA 2KRJA 1D8FA 2YUFA 2EROA 2OXWA 1AKLA 1IABA 3LJZA 1GE7A 1QICA 2X3BA 3HY7A 3DNGA 1CK7A 4ZR5A 1HFCA 3TSKA 1C8TA 1O0QA 4GWNA 3HY9A 5I4OA 3DWBA 1ZVXA 3F16A 1G05A 1XFUA 3F1AA 4H1QA 3MA2A 5JMYA 2J83A 1G4KA 1SMPA 4XM7A 1KUKA 1KAPP 3I7IA 1JJ9A 3VTGA 1HFSA 2XS4A 3VI1A 3KEJA 4L6TA 1JAPA 2JNPA 4PKVA 3O64A 1G12A 3I7GA 1ZXVA 1GO7P 4GF1A 1AYKA 1QJJA 1SLMA 1QIAA 1OS9A 3Q2HA 2TCLA 3ZXHA 2DDFA 4XCTA 3HDAP 3EDZA 3CKIA 1I1IP 5D3CA 1XUDA 3EHXA 3O2XA 2JSDA 1MMPA 3RTSA 1WNIA 2O36A 4XBHA 2MLSA 1C3IA 3LIRA 1ASTA 1BSWA 5D2BA 3UVCA 1ND1A 1FBLA 1OM7A 2W12A 3N2UA 1JK3A 3LQ0A 4AYKA 4L63A 1L6JA 2XS3A 2ERQA 1R54A 1HV5A 1R55A 4HX3A 1ATLA 3EHYA 3LUNA 1I76A 2OZRA 3KHIA 1BKCI 1G9KA 4QKZA 4GR8A 2FV5A 4HMAA 2QPJA 3DL1A 2YIGA 4WF6A 2A8HA 1DMTA 4AUOA 1GKCA 1OM8A 1XFWA 2AYKA 5CXAA 2YB9A 3EDIA 1CIZA 4G0DA 1PWPA 5BPAA 5I3MA 1R1IA 3LJTA 2W13A 1JANA 2OY4A 3LGPA 2MZIA 3BA0A 2WO8A 1SRPA 1CQRA 3KRYA 1C7KA 1CAQA 1RMZA 4GUYA 5D1TA 1QIBA 3SHIA 2MZEA 1A85A 3WV1A 3KMCA 4PKSA 1KUGA 1UEAA 2OW1A 2W0DA 2ERPA 3F19A 3N2VA 4FXYP 1SLNA 2E2DA 5CUHA 1Y8JA 4JA1A 2OW2A 4FVLA 3K7NA 1UTZA 3LIKA 3B92A 1G49A 1RM8A 2X7MA 2OVZA 3HYGA 2CLTA 2PJTA 2JIHA 1JIZA 3EWJA 3P1VA 3LKAA 5I2ZA 2Y6CA 4XM6A 1BQOA 1PWQA 2OY2A 1KUFA 2Z2DA 1J7NA 3P24A 4H2EA 1BUDA 1OM6A 3L0TA 1SU3A 2X3AA 1BKCE 2L0RA 5B5PA 4JQGA 1DTHA 3KECA 1ZTQA 2V4BA 4H3XA 4EFSA 1CGLA 3F15A 3DTIA 4JIJA 3KMEA 3Q2GA 2D1OA 1GE6A 1ZP5A 2MZHA 1PWVA 4DF9A 4IUWA 4PKTA 2RJQA 3DPEA 1XUCA 4ON1A 2N8RA 4AIGA 3G5CA 1CGEA 3HBUP 1JH1A 3TS4A 5I12A 1JAQA 3B8ZA 3AYUA 4I03A 1PWUA 5H8XA 1YOUA 3LK8A 1MNCA 2FV9A 1XFVA 1Q3AA 3WV2A 2OVXA 3LEAA 1Y0VA 1UMTA 2E3XA 1XFYA 3K7LA 2D1NA 4J4MA 1KUIA 1YQYA 2USNA 4GWMA 1UMSA 3LMCA 3KEKA 3U1RA 3HB2P 456CA 3DPFA 3USNA 4FXQA 1IADA 1R1HA 3ZVSA 2W15A 4IN9A 4PKQA 4CTHA 4L19A 3LQBA 4H49A 1BZSA 3E8RA 4A3WA 2Y6DA 1B3DA 3KWVC 4GR0A 1SATA 1K7GA 1CGFA 4H76A 2OXZA 3DTKA 4I35A 4FU4A 2O3EA 1USNA 5BOYA 1HOVA 3HDBA 1GKDA 1OMJA 1EUBA 1ZS0A 4WKIA 2OXUA 5CZMA 2W14A 4WKEA 5I0LA 1YP1A 1D7XA 1UTTA 2JT5A 1JAOA 2OI0A 4DD8A 3LUMA 2DW0A 1XFXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DW2 A;  4AXQ A;  4A7B A;  2OW9 A;  3F18 A;  1B8Y A;  3NX7 A;  1ROS A;  1Y93 A;  2JT6 A;  1D8M A;  1H71 P;  1HTD A;  1D5J A;  1K7Q A;  3L0V A;  3LIL A;  1IAG A;  2OW0 A;  4Q1L A;  4JPA A;  1ZXC A;  3WV3 A;  3LE9 A;  1K7I A;  5D7W A;  1GE5 A;  4GR3 A;  1O0T A;  2K9C A;  1FM1 A;  1BQQ M;  1BKC A;  1PWW A;  5BOT A;  1Z3J A;  1S4B P;  1KUH A;  5L7F A;  4G9L A;  4H84 A;  3B2Z A;  3EDG A;  1KBC A;  1QJI A;  1QUA A;  1AF0 A;  3G42 A;  4ILW D;  4WK7 A;  1MMB A;  4PKW A;  2CKI A;  1EAK A;  3AIG A;  1JKY A;  3ZUK A;  2J0T A;  3ELM A;  1BM6 A;  1IAE A;  5I43 A;  3TT4 A;  1A86 A;  1IAA A;  2WO9 A;  5B5O A;  3HBV P;  2WOA A;  5L79 A;  3AYK A;  966C A;  2MLR A;  2RJP A;  4R3V A;  3RTT A;  2X3C A;  1R1J A;  1HY7 A;  2SRT A;  2K2G A;  2AIG P;  1XFZ A;  1XUR A;  1I73 A;  1EB6 A;  3V96 B;  3OHO A;  1BIW A;  4WZV A;  3LJG A;  4PKU A;  1OO9 A;  2HU6 A;  4XM8 A;  4IJO A;  1MMR A;  2DW1 A;  1GO8 P;  3EDH A;  3DSL A;  4GQL A;  3GBO A;  5LAB A;  4JP4 A;  1FLS A;  3F17 A;  3OHL A;  4H82 A;  1JIW P;  1YCM A;  4DPE A;  1BUV M;  2I47 A;  5D1S A;  2POJ A;  4DV8 A;  1IAC A;  1MMQ A;  3TVC A;  830C A;  1GXD A;  2DDY A;  1OS2 A;  4H30 A;  4PKR A;  5D1U A;  1CXV A;  2KRJ A;  1D8F A;  2ERO A;  2OXW A;  1AKL A;  1IAB A;  3LJZ A;  1GE7 A;  1QIC A;  2X3B A;  3HY7 A;  3DNG A;  1CK7 A;  4ZR5 A;  1HFC A;  3TSK A;  1C8T A;  1O0Q A;  4GWN A;  3HY9 A;  5I4O A;  3DWB A;  1ZVX A;  3F16 A;  1G05 A;  1XFU A;  3F1A A;  4H1Q A;  3MA2 A;  5JMY A;  2J83 A;  1G4K A;  1SMP A;  4XM7 A;  1KUK A;  1KAP P;  3I7I A;  1JJ9 A;  3VTG A;  1HFS A;  2XS4 A;  3VI1 A;  3KEJ A;  4L6T A;  1JAP A;  2JNP A;  4PKV A;  3O64 A;  1G12 A;  3I7G A;  1ZXV A;  1GO7 P;  4GF1 A;  1AYK A;  1QJJ A;  1SLM A;  1QIA A;  1OS9 A;  3Q2H A;  2TCL A;  3ZXH A;  2DDF A;  4XCT A;  3HDA P;  3EDZ A;  3CKI A;  1I1I P;  5D3C A;  1XUD A;  3EHX A;  3O2X A;  2JSD A;  1MMP A;  3RTS A;  1WNI A;  2O36 A;  4XBH A;  2MLS A;  1C3I A;  3LIR A;  1AST A;  1BSW A;  5D2B A;  3UVC A;  1ND1 A;  1FBL A;  1OM7 A;  2W12 A;  3N2U A;  1JK3 A;  3LQ0 A;  4AYK A;  4L63 A;  1L6J A;  2XS3 A;  2ERQ A;  1R54 A;  1HV5 A;  1R55 A;  4HX3 A;  1ATL A;  3EHY A;  3LUN A;  1I76 A;  2OZR A;  3KHI A;  1BKC I;  1G9K A;  4QKZ A;  4GR8 A;  2FV5 A;  4HMA A;  2QPJ A;  3DL1 A;  2YIG A;  4WF6 A;  2A8H A;  1DMT A;  4AUO A;  1GKC A;  1OM8 A;  1XFW A;  2AYK A;  5CXA A;  2YB9 A;  3EDI A;  1CIZ A;  4G0D A;  1PWP A;  5BPA A;  5I3M A;  1R1I A;  3LJT A;  2W13 A;  1JAN A;  2OY4 A;  3LGP A;  2MZI A;  3BA0 A;  2WO8 A;  1SRP A;  1CQR A;  3KRY A;  1C7K A;  1CAQ A;  1RMZ A;  4GUY A;  5D1T A;  1QIB A;  3SHI A;  2MZE A;  1A85 A;  3WV1 A;  3KMC A;  4PKS A;  1KUG A;  1UEA A;  2OW1 A;  2W0D A;  2ERP A;  3F19 A;  3N2V A;  4FXY P;  1SLN A;  2E2D A;  5CUH A;  1Y8J A;  4JA1 A;  2OW2 A;  4FVL A;  3K7N A;  1UTZ A;  3LIK A;  3B92 A;  1G49 A;  1RM8 A;  2X7M A;  2OVZ A;  3HYG A;  2CLT A;  2PJT A;  2JIH A;  1JIZ A;  3EWJ A;  3P1V A;  3LKA A;  5I2Z A;  2Y6C A;  4XM6 A;  1BQO A;  1PWQ A;  2OY2 A;  1KUF A;  2Z2D A;  1J7N A;  3P24 A;  4H2E A;  1BUD A;  1OM6 A;  3L0T A;  1SU3 A;  2X3A A;  1BKC E;  2L0R A;  5B5P A;  4JQG A;  1DTH A;  3KEC A;  1ZTQ A;  2V4B A;  4H3X A;  4EFS A;  1CGL A;  3F15 A;  4JIJ A;  3KME A;  3Q2G A;  2D1O A;  1GE6 A;  1ZP5 A;  2MZH A;  1PWV A;  4DF9 A;  4IUW A;  4PKT A;  2RJQ A;  3DPE A;  1XUC A;  4ON1 A;  2N8R A;  4AIG A;  3G5C A;  1CGE A;  3HBU P;  1JH1 A;  3TS4 A;  5I12 A;  1JAQ A;  3B8Z A;  3AYU A;  4I03 A;  1PWU A;  5H8X A;  1YOU A;  3LK8 A;  1MNC A;  2FV9 A;  1XFV A;  1Q3A A;  3WV2 A;  2OVX A;  3LEA A;  1Y0V A;  1UMT A;  2E3X A;  1XFY A;  3K7L A;  2D1N A;  4J4M A;  1KUI A;  1YQY A;  2USN A;  4GWM A;  1UMS A;  3LMC A;  3KEK A;  3U1R A;  3HB2 P;  456C A;  3DPF A;  3USN A;  4FXQ A;  1IAD A;  1R1H A;  3ZVS A;  2W15 A;  4IN9 A;  4PKQ A;  4CTH A;  4L19 A;  3LQB A;  4H49 A;  1BZS A;  3E8R A;  4A3W A;  2Y6D A;  1B3D A;  3KWV C;  4GR0 A;  1SAT A;  1K7G A;  1CGF A;  4H76 A;  2OXZ A;  4I35 A;  4FU4 A;  2O3E A;  1USN A;  5BOY A;  1HOV A;  3HDB A;  1GKD A;  1OMJ A;  1EUB A;  1ZS0 A;  4WKI A;  2OXU A;  5CZM A;  2W14 A;  4WKE A;  5I0L A;  1YP1 A;  1D7X A;  1UTT A;  2JT5 A;  1JAO A;  2OI0 A;  4DD8 A;  3LUM A;  2DW0 A;  1XFX A; 
#chains in the Genus database with same CATH topology
 2DW2 A;  4AXQ A;  4A7B A;  2OW9 A;  3F18 A;  1B8Y A;  3NX7 A;  1ROS A;  1Y93 A;  2JT6 A;  1D8M A;  1H71 P;  1HTD A;  1D5J A;  1K7Q A;  3L0V A;  3LIL A;  1IAG A;  2OW0 A;  4Q1L A;  4JPA A;  1ZXC A;  3WV3 A;  3LE9 A;  1K7I A;  5D7W A;  1GE5 A;  4GR3 A;  1O0T A;  2K9C A;  4L7A A;  1FM1 A;  1BQQ M;  1BKC A;  1PWW A;  5BOT A;  1Z3J A;  1S4B P;  1KUH A;  5L7F A;  4G9L A;  4H84 A;  3B2Z A;  3EDG A;  1KBC A;  1QJI A;  1QUA A;  1AF0 A;  3G42 A;  4ILW D;  4WK7 A;  1MMB A;  4PKW A;  2CKI A;  1EAK A;  3AIG A;  1JKY A;  3ZUK A;  2J0T A;  3ELM A;  1BM6 A;  1IAE A;  5I43 A;  3TT4 A;  1A86 A;  1IAA A;  2WO9 A;  5B5O A;  3HBV P;  2WOA A;  5L79 A;  3AYK A;  966C A;  2MLR A;  2RJP A;  4R3V A;  3RTT A;  2X3C A;  1R1J A;  1HY7 A;  2SRT A;  2K2G A;  2AIG P;  1XFZ A;  1XUR A;  1I73 A;  1EB6 A;  3V96 B;  3OHO A;  1BIW A;  4WZV A;  3LJG A;  4PKU A;  1OO9 A;  2HU6 A;  4XM8 A;  4IJO A;  1MMR A;  2DW1 A;  1GO8 P;  3EDH A;  3DSL A;  4GQL A;  3GBO A;  5LAB A;  4JP4 A;  1FLS A;  3F17 A;  3OHL A;  4H82 A;  3DTE A;  1JIW P;  1YCM A;  4DPE A;  1BUV M;  2I47 A;  5D1S A;  2POJ A;  4DV8 A;  1IAC A;  1MMQ A;  3TVC A;  830C A;  1GXD A;  2DDY A;  1OS2 A;  4H30 A;  4PKR A;  5D1U A;  1CXV A;  2KRJ A;  1D8F A;  2YUF A;  2ERO A;  2OXW A;  1AKL A;  1IAB A;  3LJZ A;  1GE7 A;  1QIC A;  2X3B A;  3HY7 A;  3DNG A;  1CK7 A;  4ZR5 A;  1HFC A;  3TSK A;  1C8T A;  1O0Q A;  4GWN A;  3HY9 A;  5I4O A;  3DWB A;  1ZVX A;  3F16 A;  1G05 A;  1XFU A;  3F1A A;  4H1Q A;  3MA2 A;  5JMY A;  2J83 A;  1G4K A;  1SMP A;  4XM7 A;  1KUK A;  1KAP P;  3I7I A;  1JJ9 A;  3VTG A;  1HFS A;  2XS4 A;  3VI1 A;  3KEJ A;  4L6T A;  1JAP A;  2JNP A;  4PKV A;  3O64 A;  1G12 A;  3I7G A;  1ZXV A;  1GO7 P;  4GF1 A;  1AYK A;  1QJJ A;  1SLM A;  1QIA A;  1OS9 A;  3Q2H A;  2TCL A;  3ZXH A;  2DDF A;  4XCT A;  3HDA P;  3EDZ A;  3CKI A;  1I1I P;  5D3C A;  1XUD A;  3EHX A;  3O2X A;  2JSD A;  1MMP A;  3RTS A;  1WNI A;  2O36 A;  4XBH A;  2MLS A;  1C3I A;  3LIR A;  1AST A;  1BSW A;  5D2B A;  3UVC A;  1ND1 A;  1FBL A;  1OM7 A;  2W12 A;  3N2U A;  1JK3 A;  3LQ0 A;  4AYK A;  4L63 A;  1L6J A;  2XS3 A;  2ERQ A;  1R54 A;  1HV5 A;  1R55 A;  4HX3 A;  1ATL A;  3EHY A;  3LUN A;  1I76 A;  2OZR A;  3KHI A;  1BKC I;  1G9K A;  4QKZ A;  4GR8 A;  2FV5 A;  4HMA A;  2QPJ A;  3DL1 A;  2YIG A;  4WF6 A;  2A8H A;  1DMT A;  4AUO A;  1GKC A;  1OM8 A;  1XFW A;  2AYK A;  5CXA A;  2YB9 A;  3EDI A;  1CIZ A;  4G0D A;  1OZ9 A;  1PWP A;  5BPA A;  5I3M A;  1R1I A;  3LJT A;  2W13 A;  1JAN A;  2OY4 A;  3LGP A;  2MZI A;  3BA0 A;  1XAX A;  2WO8 A;  1SRP A;  1CQR A;  3KRY A;  1C7K A;  1CAQ A;  1RMZ A;  4GUY A;  5D1T A;  1QIB A;  3SHI A;  2MZE A;  1A85 A;  3WV1 A;  3KMC A;  4PKS A;  1KUG A;  1UEA A;  2OW1 A;  2W0D A;  2ERP A;  3F19 A;  3N2V A;  4FXY P;  1SLN A;  2E2D A;  5CUH A;  1Y8J A;  4JA1 A;  2OW2 A;  4FVL A;  3K7N A;  1UTZ A;  3LIK A;  3B92 A;  1G49 A;  1RM8 A;  2X7M A;  2OVZ A;  3HYG A;  2CLT A;  2PJT A;  2JIH A;  1JIZ A;  3EWJ A;  3P1V A;  3LKA A;  5I2Z A;  1XM5 A;  2Y6C A;  4XM6 A;  1BQO A;  1PWQ A;  2OY2 A;  1KUF A;  2Z2D A;  1J7N A;  3P24 A;  4H2E A;  1BUD A;  1OM6 A;  3L0T A;  1SU3 A;  2X3A A;  1BKC E;  2L0R A;  5B5P A;  4JQG A;  1DTH A;  3KEC A;  1ZTQ A;  2V4B A;  4H3X A;  4EFS A;  1CGL A;  3F15 A;  3DTI A;  4JIJ A;  3KME A;  3Q2G A;  2D1O A;  1GE6 A;  1ZP5 A;  2MZH A;  1PWV A;  4DF9 A;  4IUW A;  4PKT A;  2RJQ A;  3DPE A;  1XUC A;  4ON1 A;  2N8R A;  4AIG A;  3G5C A;  1CGE A;  3HBU P;  1JH1 A;  3TS4 A;  5I12 A;  1JAQ A;  3B8Z A;  3AYU A;  4I03 A;  1PWU A;  5H8X A;  1YOU A;  3LK8 A;  1MNC A;  2FV9 A;  1XFV A;  1Q3A A;  3WV2 A;  2OVX A;  3LEA A;  1Y0V A;  1UMT A;  2E3X A;  1XFY A;  3K7L A;  2D1N A;  4J4M A;  1KUI A;  1YQY A;  2USN A;  4GWM A;  1UMS A;  3LMC A;  3KEK A;  3U1R A;  3HB2 P;  456C A;  3DPF A;  3USN A;  4FXQ A;  1IAD A;  1R1H A;  3ZVS A;  2W15 A;  4IN9 A;  4PKQ A;  4CTH A;  4L19 A;  1TVI A;  3LQB A;  4H49 A;  1BZS A;  3E8R A;  4A3W A;  2Y6D A;  1B3D A;  3KWV C;  4GR0 A;  1SAT A;  1K7G A;  1CGF A;  4H76 A;  2OXZ A;  3DTK A;  4I35 A;  4FU4 A;  2O3E A;  1USN A;  5BOY A;  1HOV A;  3HDB A;  1GKD A;  1OMJ A;  1EUB A;  1ZS0 A;  4WKI A;  2OXU A;  5CZM A;  2W14 A;  4WKE A;  5I0L A;  1YP1 A;  1D7X A;  1UTT A;  2JT5 A;  1JAO A;  2OI0 A;  4DD8 A;  3LUM A;  2DW0 A;  1XFX A; 
#chains in the Genus database with same CATH homology
 2DW2 A;  4AXQ A;  4A7B A;  2OW9 A;  3F18 A;  1B8Y A;  3NX7 A;  1ROS A;  1Y93 A;  2JT6 A;  1D8M A;  1H71 P;  1HTD A;  1D5J A;  1K7Q A;  3L0V A;  3LIL A;  1IAG A;  2OW0 A;  4Q1L A;  4JPA A;  1ZXC A;  3WV3 A;  3LE9 A;  1K7I A;  5D7W A;  1GE5 A;  4GR3 A;  1O0T A;  2K9C A;  4L7A A;  1FM1 A;  1BQQ M;  1BKC A;  1PWW A;  5BOT A;  1Z3J A;  1S4B P;  1KUH A;  5L7F A;  4G9L A;  4H84 A;  3B2Z A;  3EDG A;  1KBC A;  1QJI A;  1QUA A;  1AF0 A;  3G42 A;  4ILW D;  4WK7 A;  1MMB A;  4PKW A;  2CKI A;  1EAK A;  3AIG A;  1JKY A;  3ZUK A;  2J0T A;  3ELM A;  1BM6 A;  1IAE A;  5I43 A;  3TT4 A;  1A86 A;  1IAA A;  2WO9 A;  5B5O A;  3HBV P;  2WOA A;  5L79 A;  3AYK A;  966C A;  2MLR A;  2RJP A;  4R3V A;  3RTT A;  2X3C A;  1R1J A;  1HY7 A;  2SRT A;  2K2G A;  2AIG P;  1XFZ A;  1XUR A;  1I73 A;  1EB6 A;  3V96 B;  3OHO A;  1BIW A;  4WZV A;  3LJG A;  4PKU A;  1OO9 A;  2HU6 A;  4XM8 A;  4IJO A;  1MMR A;  2DW1 A;  1GO8 P;  3EDH A;  3DSL A;  4GQL A;  3GBO A;  5LAB A;  4JP4 A;  1FLS A;  3F17 A;  3OHL A;  4H82 A;  3DTE A;  1JIW P;  1YCM A;  4DPE A;  1BUV M;  2I47 A;  5D1S A;  2POJ A;  4DV8 A;  1IAC A;  1MMQ A;  3TVC A;  830C A;  1GXD A;  2DDY A;  1OS2 A;  4H30 A;  4PKR A;  5D1U A;  1CXV A;  2KRJ A;  1D8F A;  2YUF A;  2ERO A;  2OXW A;  1AKL A;  1IAB A;  3LJZ A;  1GE7 A;  1QIC A;  2X3B A;  3HY7 A;  3DNG A;  1CK7 A;  4ZR5 A;  1HFC A;  3TSK A;  1C8T A;  1O0Q A;  4GWN A;  3HY9 A;  5I4O A;  3DWB A;  1ZVX A;  3F16 A;  1G05 A;  1XFU A;  3F1A A;  4H1Q A;  3MA2 A;  5JMY A;  2J83 A;  1G4K A;  1SMP A;  4XM7 A;  1KUK A;  1KAP P;  3I7I A;  1JJ9 A;  3VTG A;  1HFS A;  2XS4 A;  3VI1 A;  3KEJ A;  4L6T A;  1JAP A;  2JNP A;  4PKV A;  3O64 A;  1G12 A;  3I7G A;  1ZXV A;  1GO7 P;  4GF1 A;  1AYK A;  1QJJ A;  1SLM A;  1QIA A;  1OS9 A;  3Q2H A;  2TCL A;  3ZXH A;  2DDF A;  4XCT A;  3HDA P;  3EDZ A;  3CKI A;  1I1I P;  5D3C A;  1XUD A;  3EHX A;  3O2X A;  2JSD A;  1MMP A;  3RTS A;  1WNI A;  2O36 A;  4XBH A;  2MLS A;  1C3I A;  3LIR A;  1AST A;  1BSW A;  5D2B A;  3UVC A;  1ND1 A;  1FBL A;  1OM7 A;  2W12 A;  3N2U A;  1JK3 A;  3LQ0 A;  4AYK A;  4L63 A;  1L6J A;  2XS3 A;  2ERQ A;  1R54 A;  1HV5 A;  1R55 A;  4HX3 A;  1ATL A;  3EHY A;  3LUN A;  1I76 A;  2OZR A;  3KHI A;  1BKC I;  1G9K A;  4QKZ A;  4GR8 A;  2FV5 A;  4HMA A;  2QPJ A;  3DL1 A;  2YIG A;  4WF6 A;  2A8H A;  1DMT A;  4AUO A;  1GKC A;  1OM8 A;  1XFW A;  2AYK A;  5CXA A;  2YB9 A;  3EDI A;  1CIZ A;  4G0D A;  1PWP A;  5BPA A;  5I3M A;  1R1I A;  3LJT A;  2W13 A;  1JAN A;  2OY4 A;  3LGP A;  2MZI A;  3BA0 A;  2WO8 A;  1SRP A;  1CQR A;  3KRY A;  1C7K A;  1CAQ A;  1RMZ A;  4GUY A;  5D1T A;  1QIB A;  3SHI A;  2MZE A;  1A85 A;  3WV1 A;  3KMC A;  4PKS A;  1KUG A;  1UEA A;  2OW1 A;  2W0D A;  2ERP A;  3F19 A;  3N2V A;  4FXY P;  1SLN A;  2E2D A;  5CUH A;  1Y8J A;  4JA1 A;  2OW2 A;  4FVL A;  3K7N A;  1UTZ A;  3LIK A;  3B92 A;  1G49 A;  1RM8 A;  2X7M A;  2OVZ A;  3HYG A;  2CLT A;  2PJT A;  2JIH A;  1JIZ A;  3EWJ A;  3P1V A;  3LKA A;  5I2Z A;  2Y6C A;  4XM6 A;  1BQO A;  1PWQ A;  2OY2 A;  1KUF A;  2Z2D A;  1J7N A;  3P24 A;  4H2E A;  1BUD A;  1OM6 A;  3L0T A;  1SU3 A;  2X3A A;  1BKC E;  2L0R A;  5B5P A;  4JQG A;  1DTH A;  3KEC A;  1ZTQ A;  2V4B A;  4H3X A;  4EFS A;  1CGL A;  3F15 A;  3DTI A;  4JIJ A;  3KME A;  3Q2G A;  2D1O A;  1GE6 A;  1ZP5 A;  2MZH A;  1PWV A;  4DF9 A;  4IUW A;  4PKT A;  2RJQ A;  3DPE A;  1XUC A;  4ON1 A;  2N8R A;  4AIG A;  3G5C A;  1CGE A;  3HBU P;  1JH1 A;  3TS4 A;  5I12 A;  1JAQ A;  3B8Z A;  3AYU A;  4I03 A;  1PWU A;  5H8X A;  1YOU A;  3LK8 A;  1MNC A;  2FV9 A;  1XFV A;  1Q3A A;  3WV2 A;  2OVX A;  3LEA A;  1Y0V A;  1UMT A;  2E3X A;  1XFY A;  3K7L A;  2D1N A;  4J4M A;  1KUI A;  1YQY A;  2USN A;  4GWM A;  1UMS A;  3LMC A;  3KEK A;  3U1R A;  3HB2 P;  456C A;  3DPF A;  3USN A;  4FXQ A;  1IAD A;  1R1H A;  3ZVS A;  2W15 A;  4IN9 A;  4PKQ A;  4CTH A;  4L19 A;  3LQB A;  4H49 A;  1BZS A;  3E8R A;  4A3W A;  2Y6D A;  1B3D A;  3KWV C;  4GR0 A;  1SAT A;  1K7G A;  1CGF A;  4H76 A;  2OXZ A;  3DTK A;  4I35 A;  4FU4 A;  2O3E A;  1USN A;  5BOY A;  1HOV A;  3HDB A;  1GKD A;  1OMJ A;  1EUB A;  1ZS0 A;  4WKI A;  2OXU A;  5CZM A;  2W14 A;  4WKE A;  5I0L A;  1YP1 A;  1D7X A;  1UTT A;  2JT5 A;  1JAO A;  2OI0 A;  4DD8 A;  3LUM A;  2DW0 A;  1XFX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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