1YOUA

Crystal structure of the catalytic domain of mmp-13 complexed with a potent pyrimidinetrione inhibitor
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
168
structure length
168
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14.
pubmed doi rcsb
molecule keywords Collagenase 3
molecule tags Hydrolase
source organism Homo sapiens
total genus 49
structure length 168
sequence length 168
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2005-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1youA00
1J7NA 3VTGA 4PKUA 1QIAA 5I3MA 1BSWA 1K7QA 4XM7A 1AYKA 2OW0A 3DPEA 1ZVXA 2W0DA 2K2GA 3AYKA 3KEKA 3L0VA 2JT6A 5I2ZA 2CLTA 2AIGP 3AYUA 1R55A 2XS3A 3OHOA 4H82A 2MLSA 3NX7A 3TVCA 4FXQA 5I4OA 1K7GA 1D8MA 2X3CA 1GKDA 1YQYA 4H30A 3HY9A 3HYGA 3WV1A 3WV3A 3F17A 3TSKA 1SLMA 2W12A 2K9CA 4JA1A 1DTHA 5I12A 4AYKA 1IAAA 4H1QA 3LUMA 3BA0A 1BM6A 1HFCA 4IN9A 3ZXHA 4ZR5A 1I1IP 1SATA 3LIKA 1AF0A 1CK7A 3RTSA 4I03A 3KRYA 4XCTA 2DDYA 3ELMA 2O36A 2MLRA 2HU6A 3K7NA 4JIJA 4PKSA 1PWVA 1ATLA 1XFZA 1GKCA 3Q2GA 3LJZA 3LEAA 2JIHA 1KUGA 4G9LA 1SRPA 2OVXA 1ZXVA 4L63A 1OM6A 5D2BA 1G9KA 4WF6A 2W15A 3F1AA 3OHLA 3HBVP 5D3CA 3I7GA 1CAQA 3EDIA 1EB6A 2J83A 5D1SA 3EDHA 3VI1A 2OXUA 4FU4A 1OM7A 2OXWA 3KMEA 2YB9A 1O0TA 4HX3A 2OXZA 2MZHA 1SMPA 3KECA 1WNIA 3P24A 4GWNA 2D1NA 3KMCA 3LMCA 1R1HA 4PKWA 3EHYA 4H76A 3F19A 4CTHA 3ZUKA 2DDFA 1CGLA 1KBCA 3F18A 2Y6DA 1JIWP 1B8YA 3DNGA 3LJGA 4HMAA 1PWQA 3LE9A 4AIGA 1JAPA 2JSDA 5D1UA 4PKVA 2J0TA 3N2VA 1ZTQA 3LKAA 4QKZA 3DWBA 4GR8A 2CKIA 2QPJA 966CA 3Q2HA 1XFYA 1KAPP 1XUCA 5CZMA 4DD8A 3K7LA 3EHXA 1BQOA 1R1IA 3EDZA 4ILWD 2E3XA 5I43A 5B5OA 3DL1A 1USNA 3LQ0A 2DW1A 2E2DA 1C3IA 3ZVSA 4AUOA 1SU3A 4FVLA 2AYKA 2JT5A 1D5JA 5BOTA 3U1RA 3B92A 4G0DA 1KUKA 1JK3A 1D7XA 4I35A 5I0LA 3DSLA 2ERPA 1RMZA 3EDGA 4H49A 3KHIA 2OY2A 1JAQA 3HDBA 3SHIA 1SLNA 2OY4A 2ERQA 1HFSA 1CGFA 1PWUA 1IACA 2FV5A 1G4KA 1RM8A 1R54A 1GE6A 2O3EA 1QIBA 4WKIA 830CA 1IABA 4JPAA 2RJQA 4A3WA 4H3XA 3F16A 1AKLA 4DPEA 1Z3JA 1ZXCA 4H2EA 1BKCE 3L0TA 1ND1A 2X7MA 1I76A 4PKTA 4XM6A 1OMJA 1XURA 1XFUA 1OS9A 1S4BP 1ZP5A 1OO9A 1OM8A 3RTTA 1BKCA 2OZRA 1YOUA 1Y8JA 3B8ZA 1MNCA 1D8FA 2EROA 2WO8A 3O64A 2JNPA 5H8XA 2X3BA 3CKIA 2WO9A 3P1VA 1IADA 3G5CA 2OVZA 5D1TA 2L0RA 2MZIA 1GE5A 4AXQA 1BKCI 3MA2A 1I73A 1EAKA 1HY7A 3GBOA 1O0QA 1XUDA 4JP4A 4L6TA 1IAGA 1Q3AA 1HV5A 2USNA 2MZEA 1GO8P 1YCMA 1EUBA 4PKQA 5CXAA 3EWJA 1BZSA 4WZVA 1XFWA 1XFVA 2OW2A 2DW2A 5B5PA 1Y0VA 1K7IA 3V96B 1HOVA 1MMRA 456CA 1MMQA 2POJA 4J4MA 1BUVM 1GO7P 2OW1A 3LQBA 1H71P 3LJTA 2TCLA 1R1JA 4ON1A 2D1OA 3LIRA 1FBLA 2Y6CA 1KUFA 3N2UA 1UMTA 3TT4A 1G49A 4A7BA 1GXDA 4IUWA 1BIWA 3HBUP 2YIGA 1QJIA 1UEAA 3G42A 4DV8A 1KUHA 4DF9A 2DW0A 3F15A 3UVCA 1C8TA 3KEJA 2X3AA 1A85A 2W14A 4XM8A 1FM1A 1DMTA 4EFSA 1JAOA 2Z2DA 3HY7A 4H84A 1ZS0A 2I47A 1ASTA 4XBHA 2OI0A 3DPFA 2WOAA 1JIZA 4R3VA 1CIZA 5L79A 4IJOA 2W13A 3AIGA 5BOYA 4L19A 1QICA 1KUIA 1OS2A 4GR0A 2XS4A 2KRJA 3HDAP 4PKRA 1PWWA 1IAEA 1CXVA 1ROSA 2RJPA 4WKEA 3I7IA 1UTTA 4GQLA 4JQGA 5CUHA 5JMYA 1G05A 1QJJA 5L7FA 1YP1A 1MMPA 2FV9A 1CQRA 1Y93A 4GF1A 1BUDA 1XFXA 1C7KA 2A8HA 1QUAA 1UTZA 4Q1LA 2OW9A 5LABA 3USNA 1JH1A 2SRTA 1A86A 3LILA 3HB2P 4FXYP 1JJ9A 2V4BA 1BQQM 3B2ZA 5BPAA 5D7WA 3KWVC 3O2XA 1HTDA 4GUYA 3WV2A 1CGEA 1JKYA 4GWMA 3E8RA 1L6JA 2N8RA 4GR3A 3LK8A 1PWPA 1JANA 1UMSA 1MMBA 2PJTA 3LUNA 1G12A 1B3DA 3TS4A 4WK7A 1FLSA 1GE7A 3LGPA
chains in the Genus database with same CATH superfamily
1J7NA 3VTGA 4PKUA 1QIAA 5I3MA 1BSWA 1K7QA 4XM7A 1AYKA 2OW0A 3DPEA 1ZVXA 2W0DA 2K2GA 3AYKA 3KEKA 3L0VA 2JT6A 5I2ZA 2CLTA 2AIGP 3DTIA 3AYUA 1R55A 2XS3A 3OHOA 4H82A 2MLSA 3NX7A 3TVCA 4FXQA 5I4OA 1K7GA 1D8MA 2X3CA 1GKDA 1YQYA 4H30A 3HY9A 3HYGA 3WV1A 3WV3A 3F17A 3TSKA 1SLMA 2W12A 2K9CA 4JA1A 1DTHA 5I12A 4AYKA 1IAAA 4H1QA 3LUMA 3BA0A 1BM6A 1HFCA 4IN9A 3ZXHA 4ZR5A 1I1IP 1SATA 3LIKA 1AF0A 1CK7A 3RTSA 4I03A 3KRYA 2YUFA 4XCTA 2DDYA 3ELMA 2O36A 2MLRA 2HU6A 3K7NA 4JIJA 4PKSA 1PWVA 1ATLA 1XFZA 1GKCA 3Q2GA 3LJZA 3LEAA 2JIHA 1KUGA 4G9LA 1SRPA 2OVXA 1ZXVA 4L63A 1OM6A 5D2BA 1G9KA 4WF6A 2W15A 3F1AA 3OHLA 3HBVP 5D3CA 3I7GA 1CAQA 3EDIA 1EB6A 2J83A 5D1SA 3EDHA 1XM5A 3VI1A 2OXUA 4FU4A 1OM7A 2OXWA 3KMEA 2YB9A 1O0TA 4HX3A 2OXZA 2MZHA 1SMPA 3KECA 1WNIA 3P24A 4GWNA 2D1NA 3KMCA 3LMCA 1R1HA 4PKWA 3EHYA 4H76A 3F19A 4CTHA 3ZUKA 2DDFA 1CGLA 1KBCA 3F18A 2Y6DA 1JIWP 1B8YA 3DNGA 3LJGA 4HMAA 1PWQA 3LE9A 4AIGA 1JAPA 2JSDA 5D1UA 4PKVA 2J0TA 3N2VA 1ZTQA 3LKAA 4QKZA 3DWBA 4GR8A 2CKIA 2QPJA 966CA 3Q2HA 1XFYA 1KAPP 1XUCA 3DTEA 5CZMA 3DTKA 3K7LA 3EHXA 4DD8A 1BQOA 1R1IA 3EDZA 4ILWD 2E3XA 5I43A 5B5OA 3DL1A 1USNA 3LQ0A 2DW1A 2E2DA 1C3IA 3ZVSA 4AUOA 1SU3A 4FVLA 2AYKA 2JT5A 1D5JA 1OZ9A 5BOTA 3U1RA 3B92A 4G0DA 1KUKA 1JK3A 1D7XA 4I35A 5I0LA 3DSLA 2ERPA 1RMZA 3EDGA 4H49A 3KHIA 2OY2A 1JAQA 3HDBA 3SHIA 1SLNA 2OY4A 2ERQA 1HFSA 1CGFA 1PWUA 1IACA 2FV5A 1G4KA 1RM8A 1R54A 1GE6A 2O3EA 1QIBA 4WKIA 830CA 1IABA 4JPAA 2RJQA 4A3WA 4H3XA 3F16A 1AKLA 4DPEA 1Z3JA 1ZXCA 4H2EA 1BKCE 3L0TA 1ND1A 2X7MA 1I76A 4PKTA 4XM6A 1OMJA 1XURA 1XFUA 1OS9A 1S4BP 1ZP5A 1OO9A 1OM8A 3RTTA 1BKCA 2OZRA 1YOUA 1Y8JA 3B8ZA 1MNCA 1D8FA 2EROA 2WO8A 3O64A 2JNPA 5H8XA 2X3BA 3CKIA 2WO9A 3P1VA 1IADA 3G5CA 2OVZA 5D1TA 2L0RA 2MZIA 1GE5A 4AXQA 1BKCI 3MA2A 1I73A 1EAKA 1HY7A 3GBOA 1O0QA 1XUDA 4JP4A 4L6TA 1IAGA 1Q3AA 1XAXA 1HV5A 2USNA 2MZEA 1GO8P 1YCMA 1EUBA 4PKQA 5CXAA 3EWJA 1BZSA 4WZVA 1XFWA 1XFVA 2OW2A 2DW2A 5B5PA 1Y0VA 1K7IA 3V96B 1HOVA 1MMRA 456CA 1MMQA 2POJA 4J4MA 1BUVM 1GO7P 2OW1A 3LQBA 1H71P 3LJTA 2TCLA 1R1JA 4ON1A 2D1OA 3LIRA 1FBLA 2Y6CA 1KUFA 3N2UA 1UMTA 3TT4A 1G49A 4A7BA 1GXDA 4IUWA 1BIWA 3HBUP 2YIGA 1QJIA 1UEAA 3G42A 4DV8A 1KUHA 4DF9A 2DW0A 3F15A 3UVCA 1C8TA 3KEJA 2X3AA 1A85A 2W14A 4XM8A 1FM1A 1DMTA 4EFSA 1JAOA 2Z2DA 3HY7A 4H84A 1ZS0A 2I47A 1ASTA 4XBHA 2OI0A 3DPFA 2WOAA 1JIZA 1TVIA 4R3VA 1CIZA 4L7AA 5L79A 4IJOA 2W13A 3AIGA 5BOYA 4L19A 1QICA 1KUIA 1OS2A 4GR0A 2XS4A 2KRJA 3HDAP 4PKRA 1PWWA 1IAEA 1CXVA 1ROSA 2RJPA 4WKEA 3I7IA 1UTTA 4GQLA 4JQGA 5CUHA 5JMYA 1G05A 1QJJA 5L7FA 1YP1A 1MMPA 2FV9A 1CQRA 1Y93A 4GF1A 1BUDA 1XFXA 1C7KA 2A8HA 1QUAA 1UTZA 4Q1LA 2OW9A 5LABA 3USNA 1JH1A 2SRTA 1A86A 3LILA 3HB2P 4FXYP 1JJ9A 2V4BA 1BQQM 3B2ZA 5BPAA 5D7WA 3KWVC 3O2XA 1HTDA 4GUYA 3WV2A 1CGEA 1JKYA 4GWMA 3E8RA 1L6JA 2N8RA 4GR3A 3LK8A 1PWPA 1JANA 1UMSA 1MMBA 2PJTA 3LUNA 1G12A 1B3DA 3TS4A 4WK7A 1FLSA 1GE7A 3LGPA
chains in the Genus database with same CATH topology
1J7NA 3VTGA 4PKUA 1QIAA 5I3MA 1BSWA 1K7QA 4XM7A 1AYKA 2OW0A 3DPEA 1ZVXA 2W0DA 2K2GA 3AYKA 3KEKA 3L0VA 2JT6A 5I2ZA 2CLTA 2AIGP 3DTIA 3AYUA 1R55A 2XS3A 3OHOA 4H82A 2MLSA 3NX7A 3TVCA 4FXQA 5I4OA 1K7GA 1D8MA 2X3CA 1GKDA 1YQYA 4H30A 3HY9A 3HYGA 3WV1A 3WV3A 3F17A 3TSKA 1SLMA 2W12A 2K9CA 4JA1A 1DTHA 5I12A 4AYKA 1IAAA 4H1QA 3LUMA 3BA0A 1BM6A 1HFCA 4IN9A 3ZXHA 4ZR5A 1I1IP 1SATA 3LIKA 1AF0A 1CK7A 3RTSA 4I03A 3KRYA 2YUFA 4XCTA 2DDYA 3ELMA 2O36A 2MLRA 2HU6A 3K7NA 4JIJA 4PKSA 1PWVA 1ATLA 1XFZA 1GKCA 3Q2GA 3LJZA 3LEAA 2JIHA 1KUGA 4G9LA 1SRPA 2OVXA 1ZXVA 4L63A 1OM6A 5D2BA 1G9KA 4WF6A 2W15A 3F1AA 3OHLA 3HBVP 5D3CA 3I7GA 1CAQA 3EDIA 1EB6A 2J83A 5D1SA 3EDHA 3VI1A 2OXUA 4FU4A 1OM7A 2OXWA 3KMEA 2YB9A 1O0TA 4HX3A 2OXZA 2MZHA 1SMPA 3KECA 1WNIA 3P24A 4GWNA 2D1NA 3KMCA 3LMCA 1R1HA 4PKWA 3EHYA 4H76A 3F19A 4CTHA 3ZUKA 2DDFA 1CGLA 1KBCA 3F18A 2Y6DA 1JIWP 1B8YA 3DNGA 3LJGA 4HMAA 1PWQA 3LE9A 4AIGA 1JAPA 2JSDA 5D1UA 4PKVA 2J0TA 3N2VA 1ZTQA 3LKAA 4QKZA 3DWBA 4GR8A 2CKIA 2QPJA 966CA 3Q2HA 1XFYA 1KAPP 1XUCA 3DTEA 5CZMA 3DTKA 3K7LA 3EHXA 4DD8A 1BQOA 1R1IA 3EDZA 4ILWD 2E3XA 5I43A 5B5OA 3DL1A 1USNA 3LQ0A 2DW1A 2E2DA 1C3IA 3ZVSA 4AUOA 1SU3A 4FVLA 2AYKA 2JT5A 1D5JA 5BOTA 3U1RA 3B92A 4G0DA 1KUKA 1JK3A 1D7XA 4I35A 5I0LA 3DSLA 2ERPA 1RMZA 3EDGA 4H49A 3KHIA 2OY2A 1JAQA 3HDBA 3SHIA 1SLNA 2OY4A 2ERQA 1HFSA 1CGFA 1PWUA 1IACA 2FV5A 1G4KA 1RM8A 1R54A 1GE6A 2O3EA 1QIBA 4WKIA 830CA 1IABA 4JPAA 2RJQA 4A3WA 4H3XA 3F16A 1AKLA 4DPEA 1Z3JA 1ZXCA 4H2EA 1BKCE 3L0TA 1ND1A 2X7MA 1I76A 4PKTA 4XM6A 1OMJA 1XURA 1XFUA 1OS9A 1S4BP 1ZP5A 1OO9A 1OM8A 3RTTA 1BKCA 2OZRA 1YOUA 1Y8JA 3B8ZA 1MNCA 1D8FA 2EROA 2WO8A 3O64A 2JNPA 5H8XA 2X3BA 3CKIA 2WO9A 3P1VA 1IADA 3G5CA 2OVZA 5D1TA 2L0RA 2MZIA 1GE5A 4AXQA 1BKCI 3MA2A 1I73A 1EAKA 1HY7A 3GBOA 1O0QA 1XUDA 4JP4A 4L6TA 1IAGA 1Q3AA 1HV5A 2USNA 2MZEA 1GO8P 1YCMA 1EUBA 4PKQA 5CXAA 3EWJA 1BZSA 4WZVA 1XFWA 1XFVA 2OW2A 2DW2A 5B5PA 1Y0VA 1K7IA 3V96B 1HOVA 1MMRA 456CA 1MMQA 2POJA 4J4MA 1BUVM 1GO7P 2OW1A 3LQBA 1H71P 3LJTA 2TCLA 1R1JA 4ON1A 2D1OA 3LIRA 1FBLA 2Y6CA 1KUFA 3N2UA 1UMTA 3TT4A 1G49A 4A7BA 1GXDA 4IUWA 1BIWA 3HBUP 2YIGA 1QJIA 1UEAA 3G42A 4DV8A 1KUHA 4DF9A 2DW0A 3F15A 3UVCA 1C8TA 3KEJA 2X3AA 1A85A 2W14A 4XM8A 1FM1A 1DMTA 4EFSA 1JAOA 2Z2DA 3HY7A 4H84A 1ZS0A 2I47A 1ASTA 4XBHA 2OI0A 3DPFA 2WOAA 1JIZA 4R3VA 1CIZA 4L7AA 5L79A 4IJOA 2W13A 3AIGA 5BOYA 4L19A 1QICA 1KUIA 1OS2A 4GR0A 2XS4A 2KRJA 3HDAP 4PKRA 1PWWA 1IAEA 1CXVA 1ROSA 2RJPA 4WKEA 3I7IA 1UTTA 4GQLA 4JQGA 5CUHA 5JMYA 1G05A 1QJJA 5L7FA 1YP1A 1MMPA 2FV9A 1CQRA 1Y93A 4GF1A 1BUDA 1XFXA 1C7KA 2A8HA 1QUAA 1UTZA 4Q1LA 2OW9A 5LABA 3USNA 1JH1A 2SRTA 1A86A 3LILA 3HB2P 4FXYP 1JJ9A 2V4BA 1BQQM 3B2ZA 5BPAA 5D7WA 3KWVC 3O2XA 1HTDA 4GUYA 3WV2A 1CGEA 1JKYA 4GWMA 3E8RA 1L6JA 2N8RA 4GR3A 3LK8A 1PWPA 1JANA 1UMSA 1MMBA 2PJTA 3LUNA 1G12A 1B3DA 3TS4A 4WK7A 1FLSA 1GE7A 3LGPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J7N A;  3VTG A;  4PKU A;  1QIA A;  5I3M A;  1BSW A;  1K7Q A;  4XM7 A;  1AYK A;  2OW0 A;  3DPE A;  1ZVX A;  2W0D A;  2K2G A;  3AYK A;  3KEK A;  3L0V A;  2JT6 A;  5I2Z A;  2CLT A;  2AIG P;  3AYU A;  1R55 A;  2XS3 A;  3OHO A;  4H82 A;  2MLS A;  3NX7 A;  3TVC A;  4FXQ A;  5I4O A;  1K7G A;  1D8M A;  2X3C A;  1GKD A;  1YQY A;  4H30 A;  3HY9 A;  3HYG A;  3WV1 A;  3WV3 A;  3F17 A;  3TSK A;  1SLM A;  2W12 A;  2K9C A;  4JA1 A;  1DTH A;  5I12 A;  4AYK A;  1IAA A;  4H1Q A;  3LUM A;  3BA0 A;  1BM6 A;  1HFC A;  4IN9 A;  3ZXH A;  4ZR5 A;  1I1I P;  1SAT A;  3LIK A;  1AF0 A;  1CK7 A;  3RTS A;  4I03 A;  3KRY A;  4XCT A;  2DDY A;  3ELM A;  2O36 A;  2MLR A;  2HU6 A;  3K7N A;  4JIJ A;  4PKS A;  1PWV A;  1ATL A;  1XFZ A;  1GKC A;  3Q2G A;  3LJZ A;  3LEA A;  2JIH A;  1KUG A;  4G9L A;  1SRP A;  2OVX A;  1ZXV A;  4L63 A;  1OM6 A;  5D2B A;  1G9K A;  4WF6 A;  2W15 A;  3F1A A;  3OHL A;  3HBV P;  5D3C A;  3I7G A;  1CAQ A;  3EDI A;  1EB6 A;  2J83 A;  5D1S A;  3EDH A;  3VI1 A;  2OXU A;  4FU4 A;  1OM7 A;  2OXW A;  3KME A;  2YB9 A;  1O0T A;  4HX3 A;  2OXZ A;  2MZH A;  1SMP A;  3KEC A;  1WNI A;  3P24 A;  4GWN A;  2D1N A;  3KMC A;  3LMC A;  1R1H A;  4PKW A;  3EHY A;  4H76 A;  3F19 A;  4CTH A;  3ZUK A;  2DDF A;  1CGL A;  1KBC A;  3F18 A;  2Y6D A;  1JIW P;  1B8Y A;  3DNG A;  3LJG A;  4HMA A;  1PWQ A;  3LE9 A;  4AIG A;  1JAP A;  2JSD A;  5D1U A;  4PKV A;  2J0T A;  3N2V A;  1ZTQ A;  3LKA A;  4QKZ A;  3DWB A;  4GR8 A;  2CKI A;  2QPJ A;  966C A;  3Q2H A;  1XFY A;  1KAP P;  1XUC A;  5CZM A;  4DD8 A;  3K7L A;  3EHX A;  1BQO A;  1R1I A;  3EDZ A;  4ILW D;  2E3X A;  5I43 A;  5B5O A;  3DL1 A;  1USN A;  3LQ0 A;  2DW1 A;  2E2D A;  1C3I A;  3ZVS A;  4AUO A;  1SU3 A;  4FVL A;  2AYK A;  2JT5 A;  1D5J A;  5BOT A;  3U1R A;  3B92 A;  4G0D A;  1KUK A;  1JK3 A;  1D7X A;  4I35 A;  5I0L A;  3DSL A;  2ERP A;  1RMZ A;  3EDG A;  4H49 A;  3KHI A;  2OY2 A;  1JAQ A;  3HDB A;  3SHI A;  1SLN A;  2OY4 A;  2ERQ A;  1HFS A;  1CGF A;  1PWU A;  1IAC A;  2FV5 A;  1G4K A;  1RM8 A;  1R54 A;  1GE6 A;  2O3E A;  1QIB A;  4WKI A;  830C A;  1IAB A;  4JPA A;  2RJQ A;  4A3W A;  4H3X A;  3F16 A;  1AKL A;  4DPE A;  1Z3J A;  1ZXC A;  4H2E A;  1BKC E;  3L0T A;  1ND1 A;  2X7M A;  1I76 A;  4PKT A;  4XM6 A;  1OMJ A;  1XUR A;  1XFU A;  1OS9 A;  1S4B P;  1ZP5 A;  1OO9 A;  1OM8 A;  3RTT A;  1BKC A;  2OZR A;  1YOU A;  1Y8J A;  3B8Z A;  1MNC A;  1D8F A;  2ERO A;  2WO8 A;  3O64 A;  2JNP A;  5H8X A;  2X3B A;  3CKI A;  2WO9 A;  3P1V A;  1IAD A;  3G5C A;  2OVZ A;  5D1T A;  2L0R A;  2MZI A;  1GE5 A;  4AXQ A;  1BKC I;  3MA2 A;  1I73 A;  1EAK A;  1HY7 A;  3GBO A;  1O0Q A;  1XUD A;  4JP4 A;  4L6T A;  1IAG A;  1Q3A A;  1HV5 A;  2USN A;  2MZE A;  1GO8 P;  1YCM A;  1EUB A;  4PKQ A;  5CXA A;  3EWJ A;  1BZS A;  4WZV A;  1XFW A;  1XFV A;  2OW2 A;  2DW2 A;  5B5P A;  1Y0V A;  1K7I A;  3V96 B;  1HOV A;  1MMR A;  456C A;  1MMQ A;  2POJ A;  4J4M A;  1BUV M;  1GO7 P;  2OW1 A;  3LQB A;  1H71 P;  3LJT A;  2TCL A;  1R1J A;  4ON1 A;  2D1O A;  3LIR A;  1FBL A;  2Y6C A;  1KUF A;  3N2U A;  1UMT A;  3TT4 A;  1G49 A;  4A7B A;  1GXD A;  4IUW A;  1BIW A;  3HBU P;  2YIG A;  1QJI A;  1UEA A;  3G42 A;  4DV8 A;  1KUH A;  4DF9 A;  2DW0 A;  3F15 A;  3UVC A;  1C8T A;  3KEJ A;  2X3A A;  1A85 A;  2W14 A;  4XM8 A;  1FM1 A;  1DMT A;  4EFS A;  1JAO A;  2Z2D A;  3HY7 A;  4H84 A;  1ZS0 A;  2I47 A;  1AST A;  4XBH A;  2OI0 A;  3DPF A;  2WOA A;  1JIZ A;  4R3V A;  1CIZ A;  5L79 A;  4IJO A;  2W13 A;  3AIG A;  5BOY A;  4L19 A;  1QIC A;  1KUI A;  1OS2 A;  4GR0 A;  2XS4 A;  2KRJ A;  3HDA P;  4PKR A;  1PWW A;  1IAE A;  1CXV A;  1ROS A;  2RJP A;  4WKE A;  3I7I A;  1UTT A;  4GQL A;  4JQG A;  5CUH A;  5JMY A;  1G05 A;  1QJJ A;  5L7F A;  1YP1 A;  1MMP A;  2FV9 A;  1CQR A;  1Y93 A;  4GF1 A;  1BUD A;  1XFX A;  1C7K A;  2A8H A;  1QUA A;  1UTZ A;  4Q1L A;  2OW9 A;  5LAB A;  3USN A;  1JH1 A;  2SRT A;  1A86 A;  3LIL A;  3HB2 P;  4FXY P;  1JJ9 A;  2V4B A;  1BQQ M;  3B2Z A;  5BPA A;  5D7W A;  3KWV C;  3O2X A;  1HTD A;  4GUY A;  3WV2 A;  1CGE A;  1JKY A;  4GWM A;  3E8R A;  1L6J A;  2N8R A;  4GR3 A;  3LK8 A;  1PWP A;  1JAN A;  1UMS A;  1MMB A;  2PJT A;  3LUN A;  1G12 A;  1B3D A;  3TS4 A;  4WK7 A;  1FLS A;  1GE7 A;  3LGP A; 
#chains in the Genus database with same CATH topology
 1J7N A;  3VTG A;  4PKU A;  1QIA A;  5I3M A;  1BSW A;  1K7Q A;  4XM7 A;  1AYK A;  2OW0 A;  3DPE A;  1ZVX A;  2W0D A;  2K2G A;  3AYK A;  3KEK A;  3L0V A;  2JT6 A;  5I2Z A;  2CLT A;  2AIG P;  3DTI A;  3AYU A;  1R55 A;  2XS3 A;  3OHO A;  4H82 A;  2MLS A;  3NX7 A;  3TVC A;  4FXQ A;  5I4O A;  1K7G A;  1D8M A;  2X3C A;  1GKD A;  1YQY A;  4H30 A;  3HY9 A;  3HYG A;  3WV1 A;  3WV3 A;  3F17 A;  3TSK A;  1SLM A;  2W12 A;  2K9C A;  4JA1 A;  1DTH A;  5I12 A;  4AYK A;  1IAA A;  4H1Q A;  3LUM A;  3BA0 A;  1BM6 A;  1HFC A;  4IN9 A;  3ZXH A;  4ZR5 A;  1I1I P;  1SAT A;  3LIK A;  1AF0 A;  1CK7 A;  3RTS A;  4I03 A;  3KRY A;  2YUF A;  4XCT A;  2DDY A;  3ELM A;  2O36 A;  2MLR A;  2HU6 A;  3K7N A;  4JIJ A;  4PKS A;  1PWV A;  1ATL A;  1XFZ A;  1GKC A;  3Q2G A;  3LJZ A;  3LEA A;  2JIH A;  1KUG A;  4G9L A;  1SRP A;  2OVX A;  1ZXV A;  4L63 A;  1OM6 A;  5D2B A;  1G9K A;  4WF6 A;  2W15 A;  3F1A A;  3OHL A;  3HBV P;  5D3C A;  3I7G A;  1CAQ A;  3EDI A;  1EB6 A;  2J83 A;  5D1S A;  3EDH A;  1XM5 A;  3VI1 A;  2OXU A;  4FU4 A;  1OM7 A;  2OXW A;  3KME A;  2YB9 A;  1O0T A;  4HX3 A;  2OXZ A;  2MZH A;  1SMP A;  3KEC A;  1WNI A;  3P24 A;  4GWN A;  2D1N A;  3KMC A;  3LMC A;  1R1H A;  4PKW A;  3EHY A;  4H76 A;  3F19 A;  4CTH A;  3ZUK A;  2DDF A;  1CGL A;  1KBC A;  3F18 A;  2Y6D A;  1JIW P;  1B8Y A;  3DNG A;  3LJG A;  4HMA A;  1PWQ A;  3LE9 A;  4AIG A;  1JAP A;  2JSD A;  5D1U A;  4PKV A;  2J0T A;  3N2V A;  1ZTQ A;  3LKA A;  4QKZ A;  3DWB A;  4GR8 A;  2CKI A;  2QPJ A;  966C A;  3Q2H A;  1XFY A;  1KAP P;  1XUC A;  3DTE A;  5CZM A;  3DTK A;  3K7L A;  3EHX A;  4DD8 A;  1BQO A;  1R1I A;  3EDZ A;  4ILW D;  2E3X A;  5I43 A;  5B5O A;  3DL1 A;  1USN A;  3LQ0 A;  2DW1 A;  2E2D A;  1C3I A;  3ZVS A;  4AUO A;  1SU3 A;  4FVL A;  2AYK A;  2JT5 A;  1D5J A;  1OZ9 A;  5BOT A;  3U1R A;  3B92 A;  4G0D A;  1KUK A;  1JK3 A;  1D7X A;  4I35 A;  5I0L A;  3DSL A;  2ERP A;  1RMZ A;  3EDG A;  4H49 A;  3KHI A;  2OY2 A;  1JAQ A;  3HDB A;  3SHI A;  1SLN A;  2OY4 A;  2ERQ A;  1HFS A;  1CGF A;  1PWU A;  1IAC A;  2FV5 A;  1G4K A;  1RM8 A;  1R54 A;  1GE6 A;  2O3E A;  1QIB A;  4WKI A;  830C A;  1IAB A;  4JPA A;  2RJQ A;  4A3W A;  4H3X A;  3F16 A;  1AKL A;  4DPE A;  1Z3J A;  1ZXC A;  4H2E A;  1BKC E;  3L0T A;  1ND1 A;  2X7M A;  1I76 A;  4PKT A;  4XM6 A;  1OMJ A;  1XUR A;  1XFU A;  1OS9 A;  1S4B P;  1ZP5 A;  1OO9 A;  1OM8 A;  3RTT A;  1BKC A;  2OZR A;  1YOU A;  1Y8J A;  3B8Z A;  1MNC A;  1D8F A;  2ERO A;  2WO8 A;  3O64 A;  2JNP A;  5H8X A;  2X3B A;  3CKI A;  2WO9 A;  3P1V A;  1IAD A;  3G5C A;  2OVZ A;  5D1T A;  2L0R A;  2MZI A;  1GE5 A;  4AXQ A;  1BKC I;  3MA2 A;  1I73 A;  1EAK A;  1HY7 A;  3GBO A;  1O0Q A;  1XUD A;  4JP4 A;  4L6T A;  1IAG A;  1Q3A A;  1XAX A;  1HV5 A;  2USN A;  2MZE A;  1GO8 P;  1YCM A;  1EUB A;  4PKQ A;  5CXA A;  3EWJ A;  1BZS A;  4WZV A;  1XFW A;  1XFV A;  2OW2 A;  2DW2 A;  5B5P A;  1Y0V A;  1K7I A;  3V96 B;  1HOV A;  1MMR A;  456C A;  1MMQ A;  2POJ A;  4J4M A;  1BUV M;  1GO7 P;  2OW1 A;  3LQB A;  1H71 P;  3LJT A;  2TCL A;  1R1J A;  4ON1 A;  2D1O A;  3LIR A;  1FBL A;  2Y6C A;  1KUF A;  3N2U A;  1UMT A;  3TT4 A;  1G49 A;  4A7B A;  1GXD A;  4IUW A;  1BIW A;  3HBU P;  2YIG A;  1QJI A;  1UEA A;  3G42 A;  4DV8 A;  1KUH A;  4DF9 A;  2DW0 A;  3F15 A;  3UVC A;  1C8T A;  3KEJ A;  2X3A A;  1A85 A;  2W14 A;  4XM8 A;  1FM1 A;  1DMT A;  4EFS A;  1JAO A;  2Z2D A;  3HY7 A;  4H84 A;  1ZS0 A;  2I47 A;  1AST A;  4XBH A;  2OI0 A;  3DPF A;  2WOA A;  1JIZ A;  1TVI A;  4R3V A;  1CIZ A;  4L7A A;  5L79 A;  4IJO A;  2W13 A;  3AIG A;  5BOY A;  4L19 A;  1QIC A;  1KUI A;  1OS2 A;  4GR0 A;  2XS4 A;  2KRJ A;  3HDA P;  4PKR A;  1PWW A;  1IAE A;  1CXV A;  1ROS A;  2RJP A;  4WKE A;  3I7I A;  1UTT A;  4GQL A;  4JQG A;  5CUH A;  5JMY A;  1G05 A;  1QJJ A;  5L7F A;  1YP1 A;  1MMP A;  2FV9 A;  1CQR A;  1Y93 A;  4GF1 A;  1BUD A;  1XFX A;  1C7K A;  2A8H A;  1QUA A;  1UTZ A;  4Q1L A;  2OW9 A;  5LAB A;  3USN A;  1JH1 A;  2SRT A;  1A86 A;  3LIL A;  3HB2 P;  4FXY P;  1JJ9 A;  2V4B A;  1BQQ M;  3B2Z A;  5BPA A;  5D7W A;  3KWV C;  3O2X A;  1HTD A;  4GUY A;  3WV2 A;  1CGE A;  1JKY A;  4GWM A;  3E8R A;  1L6J A;  2N8R A;  4GR3 A;  3LK8 A;  1PWP A;  1JAN A;  1UMS A;  1MMB A;  2PJT A;  3LUN A;  1G12 A;  1B3D A;  3TS4 A;  4WK7 A;  1FLS A;  1GE7 A;  3LGP A; 
#chains in the Genus database with same CATH homology
 1J7N A;  3VTG A;  4PKU A;  1QIA A;  5I3M A;  1BSW A;  1K7Q A;  4XM7 A;  1AYK A;  2OW0 A;  3DPE A;  1ZVX A;  2W0D A;  2K2G A;  3AYK A;  3KEK A;  3L0V A;  2JT6 A;  5I2Z A;  2CLT A;  2AIG P;  3DTI A;  3AYU A;  1R55 A;  2XS3 A;  3OHO A;  4H82 A;  2MLS A;  3NX7 A;  3TVC A;  4FXQ A;  5I4O A;  1K7G A;  1D8M A;  2X3C A;  1GKD A;  1YQY A;  4H30 A;  3HY9 A;  3HYG A;  3WV1 A;  3WV3 A;  3F17 A;  3TSK A;  1SLM A;  2W12 A;  2K9C A;  4JA1 A;  1DTH A;  5I12 A;  4AYK A;  1IAA A;  4H1Q A;  3LUM A;  3BA0 A;  1BM6 A;  1HFC A;  4IN9 A;  3ZXH A;  4ZR5 A;  1I1I P;  1SAT A;  3LIK A;  1AF0 A;  1CK7 A;  3RTS A;  4I03 A;  3KRY A;  2YUF A;  4XCT A;  2DDY A;  3ELM A;  2O36 A;  2MLR A;  2HU6 A;  3K7N A;  4JIJ A;  4PKS A;  1PWV A;  1ATL A;  1XFZ A;  1GKC A;  3Q2G A;  3LJZ A;  3LEA A;  2JIH A;  1KUG A;  4G9L A;  1SRP A;  2OVX A;  1ZXV A;  4L63 A;  1OM6 A;  5D2B A;  1G9K A;  4WF6 A;  2W15 A;  3F1A A;  3OHL A;  3HBV P;  5D3C A;  3I7G A;  1CAQ A;  3EDI A;  1EB6 A;  2J83 A;  5D1S A;  3EDH A;  3VI1 A;  2OXU A;  4FU4 A;  1OM7 A;  2OXW A;  3KME A;  2YB9 A;  1O0T A;  4HX3 A;  2OXZ A;  2MZH A;  1SMP A;  3KEC A;  1WNI A;  3P24 A;  4GWN A;  2D1N A;  3KMC A;  3LMC A;  1R1H A;  4PKW A;  3EHY A;  4H76 A;  3F19 A;  4CTH A;  3ZUK A;  2DDF A;  1CGL A;  1KBC A;  3F18 A;  2Y6D A;  1JIW P;  1B8Y A;  3DNG A;  3LJG A;  4HMA A;  1PWQ A;  3LE9 A;  4AIG A;  1JAP A;  2JSD A;  5D1U A;  4PKV A;  2J0T A;  3N2V A;  1ZTQ A;  3LKA A;  4QKZ A;  3DWB A;  4GR8 A;  2CKI A;  2QPJ A;  966C A;  3Q2H A;  1XFY A;  1KAP P;  1XUC A;  3DTE A;  5CZM A;  3DTK A;  3K7L A;  3EHX A;  4DD8 A;  1BQO A;  1R1I A;  3EDZ A;  4ILW D;  2E3X A;  5I43 A;  5B5O A;  3DL1 A;  1USN A;  3LQ0 A;  2DW1 A;  2E2D A;  1C3I A;  3ZVS A;  4AUO A;  1SU3 A;  4FVL A;  2AYK A;  2JT5 A;  1D5J A;  5BOT A;  3U1R A;  3B92 A;  4G0D A;  1KUK A;  1JK3 A;  1D7X A;  4I35 A;  5I0L A;  3DSL A;  2ERP A;  1RMZ A;  3EDG A;  4H49 A;  3KHI A;  2OY2 A;  1JAQ A;  3HDB A;  3SHI A;  1SLN A;  2OY4 A;  2ERQ A;  1HFS A;  1CGF A;  1PWU A;  1IAC A;  2FV5 A;  1G4K A;  1RM8 A;  1R54 A;  1GE6 A;  2O3E A;  1QIB A;  4WKI A;  830C A;  1IAB A;  4JPA A;  2RJQ A;  4A3W A;  4H3X A;  3F16 A;  1AKL A;  4DPE A;  1Z3J A;  1ZXC A;  4H2E A;  1BKC E;  3L0T A;  1ND1 A;  2X7M A;  1I76 A;  4PKT A;  4XM6 A;  1OMJ A;  1XUR A;  1XFU A;  1OS9 A;  1S4B P;  1ZP5 A;  1OO9 A;  1OM8 A;  3RTT A;  1BKC A;  2OZR A;  1YOU A;  1Y8J A;  3B8Z A;  1MNC A;  1D8F A;  2ERO A;  2WO8 A;  3O64 A;  2JNP A;  5H8X A;  2X3B A;  3CKI A;  2WO9 A;  3P1V A;  1IAD A;  3G5C A;  2OVZ A;  5D1T A;  2L0R A;  2MZI A;  1GE5 A;  4AXQ A;  1BKC I;  3MA2 A;  1I73 A;  1EAK A;  1HY7 A;  3GBO A;  1O0Q A;  1XUD A;  4JP4 A;  4L6T A;  1IAG A;  1Q3A A;  1HV5 A;  2USN A;  2MZE A;  1GO8 P;  1YCM A;  1EUB A;  4PKQ A;  5CXA A;  3EWJ A;  1BZS A;  4WZV A;  1XFW A;  1XFV A;  2OW2 A;  2DW2 A;  5B5P A;  1Y0V A;  1K7I A;  3V96 B;  1HOV A;  1MMR A;  456C A;  1MMQ A;  2POJ A;  4J4M A;  1BUV M;  1GO7 P;  2OW1 A;  3LQB A;  1H71 P;  3LJT A;  2TCL A;  1R1J A;  4ON1 A;  2D1O A;  3LIR A;  1FBL A;  2Y6C A;  1KUF A;  3N2U A;  1UMT A;  3TT4 A;  1G49 A;  4A7B A;  1GXD A;  4IUW A;  1BIW A;  3HBU P;  2YIG A;  1QJI A;  1UEA A;  3G42 A;  4DV8 A;  1KUH A;  4DF9 A;  2DW0 A;  3F15 A;  3UVC A;  1C8T A;  3KEJ A;  2X3A A;  1A85 A;  2W14 A;  4XM8 A;  1FM1 A;  1DMT A;  4EFS A;  1JAO A;  2Z2D A;  3HY7 A;  4H84 A;  1ZS0 A;  2I47 A;  1AST A;  4XBH A;  2OI0 A;  3DPF A;  2WOA A;  1JIZ A;  4R3V A;  1CIZ A;  4L7A A;  5L79 A;  4IJO A;  2W13 A;  3AIG A;  5BOY A;  4L19 A;  1QIC A;  1KUI A;  1OS2 A;  4GR0 A;  2XS4 A;  2KRJ A;  3HDA P;  4PKR A;  1PWW A;  1IAE A;  1CXV A;  1ROS A;  2RJP A;  4WKE A;  3I7I A;  1UTT A;  4GQL A;  4JQG A;  5CUH A;  5JMY A;  1G05 A;  1QJJ A;  5L7F A;  1YP1 A;  1MMP A;  2FV9 A;  1CQR A;  1Y93 A;  4GF1 A;  1BUD A;  1XFX A;  1C7K A;  2A8H A;  1QUA A;  1UTZ A;  4Q1L A;  2OW9 A;  5LAB A;  3USN A;  1JH1 A;  2SRT A;  1A86 A;  3LIL A;  3HB2 P;  4FXY P;  1JJ9 A;  2V4B A;  1BQQ M;  3B2Z A;  5BPA A;  5D7W A;  3KWV C;  3O2X A;  1HTD A;  4GUY A;  3WV2 A;  1CGE A;  1JKY A;  4GWM A;  3E8R A;  1L6J A;  2N8R A;  4GR3 A;  3LK8 A;  1PWP A;  1JAN A;  1UMS A;  1MMB A;  2PJT A;  3LUN A;  1G12 A;  1B3D A;  3TS4 A;  4WK7 A;  1FLS A;  1GE7 A;  3LGP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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