2A8HA

Crystal structure of catalytic domain of tace with thiomorpholine sulfonamide hydroxamate inhibitor
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
259
structure length
259
Chain Sequence
b'DPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADAM 17
publication title Acetylenic TACE inhibitors. Part 3: Thiomorpholine sulfonamide hydroxamates.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 84
structure length 259
sequence length 259
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2005-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2a8hA00
1QUAA 1KUIA 3HDBA 1DMTA 1RM8A 3G5CA 1MMBA 4PKUA 1FLSA 1B3DA 3KRYA 3EDZA 3DSLA 1ROSA 3TT4A 3Q2HA 1OS2A 1MNCA 1AF0A 3TSKA 3L0TA 1C7KA 2MZIA 1KUGA 4IJOA 1Q3AA 2AYKA 2WO9A 3SHIA 3B8ZA 3TS4A 2I47A 5CXAA 3USNA 1J7NA 1XFXA 1XFZA 1BKCA 1ZXVA 2RJQA 3LQ0A 2QPJA 5D1SA 3LK8A 5D3CA 2DW1A 1I76A 5B5PA 2YIGA 3KEKA 1Y0VA 1BUVM 5D1UA 3MA2A 1HFSA 1I1IP 4JA1A 4CTHA 2POJA 5JMYA 4IN9A 2HU6A 1MMPA 2WO8A 2K9CA 2DW0A 1IADA 3F18A 3HB2P 1HY7A 4AIGA 2OZRA 2AIGP 4HX3A 4XBHA 2ERQA 3B2ZA 3WV1A 3O64A 2Y6CA 3KHIA 1ASTA 1BQQM 1G05A 2JT6A 1DTHA 1AKLA 5B5OA 3ZVSA 5BPAA 5D7WA 1YQYA 2A8HA 1HV5A 5CZMA 3ZXHA 3E8RA 1IAEA 1SLMA 3LIKA 2X3CA 3KEJA 3WV2A 4PKVA 1Y93A 2CKIA 1Y8JA 1YCMA 4I35A 2OVZA 1MMQA 4DD8A 4H76A 1UEAA 4GWMA 2D1NA 1SATA 4G0DA 1QJJA 1PWPA 1CAQA 1IAAA 4H49A 3LMCA 4FVLA 1D5JA 1YP1A 2JT5A 1SU3A 1OM6A 2L0RA 1IABA 1JH1A 3G42A 3GBOA 1ZXCA 3RTSA 1GE6A 4H3XA 1QIAA 1CGLA 3K7NA 5BOTA 1R1JA 1JANA 1IAGA 1JAOA 3AYKA 3LQBA 1SMPA 1MMRA 3KECA 1K7GA 4A3WA 1Z3JA 1ZP5A 3N2UA 1USNA 4G9LA 4WZVA 2ERPA 2WOAA 1BKCE 1YOUA 4WF6A 3OHLA 4FXQA 3K7LA 2K2GA 2Z2DA 3B92A 2EROA 5I43A 3CKIA 1D8MA 1BIWA 2W15A 3N2VA 4PKQA 3P1VA 1BKCI 2N8RA 3KWVC 4GF1A 1G9KA 3LKAA 2OI0A 2TCLA 1CK7A 1XUCA 3KMEA 4QKZA 3DPEA 1C8TA 1OMJA 3HBVP 3HYGA 4ILWD 4JIJA 4A7BA 2XS3A 4EFSA 4H1QA 1XFYA 3EDGA 5CUHA 966CA 3LILA 1R1HA 4XM6A 4L19A 1A85A 4WKEA 2W14A 5L7FA 4GQLA 1G4KA 1GKCA 1EAKA 2DDFA 1GKDA 2OW0A 3EDIA 5D2BA 3HDAP 3ZUKA 1I73A 5L79A 4JPAA 1UMTA 1BQOA 1JIWP 3DWBA 3LEAA 1BZSA 1C3IA 2W0DA 4Q1LA 3LJGA 3BA0A 4JQGA 3VTGA 1XUDA 456CA 1R55A 1JIZA 1K7IA 2X3BA 4DV8A 1GE7A 1OM8A 1JKYA 4DF9A 1UMSA 5I12A 4IUWA 3LJTA 5I0LA 2MZEA 4AYKA 1WNIA 1HFCA 2JIHA 3AIGA 3LIRA 1OM7A 2PJTA 1GE5A 2FV5A 4R3VA 3RTTA 1OO9A 2YB9A 2USNA 4FXYP 4PKTA 1EUBA 1R1IA 2OXUA 4L63A 1R54A 5H8XA 4GR3A 4FU4A 2MLRA 4XM8A 2O36A 3F1AA 3VI1A 1GXDA 1JAQA 2DDYA 4DPEA 2XS4A 1PWQA 4J4MA 2OXWA 1CXVA 5I3MA 4XM7A 1HOVA 3KMCA 1SLNA 5BOYA 2E2DA 2MLSA 1ZVXA 2CLTA 1GO8P 3EHXA 3F19A 1O0TA 3LE9A 1GO7P 4PKWA 1XFWA 2DW2A 2X7MA 2O3EA 1KUFA 3EWJA 5D1TA 1EB6A 1PWVA 3V96B 2JNPA 1KBCA 1CGFA 1CIZA 2OXZA 1G49A 3LGPA 3L0VA 3F16A 1QIBA 1FM1A 1CQRA 3U1RA 3EDHA 1CGEA 4H30A 3LUMA 1UTTA 1QICA 4H82A 1XFUA 2E3XA 4PKSA 1KUHA 1XFVA 1SRPA 2OW9A 1BSWA 2SRTA 2OVXA 1UTZA 2Y6DA 4HMAA 3TVCA 3I7IA 3I7GA 3P24A 4H84A 2J83A 2OW2A 2OY4A 2OY2A 1G12A 830CA 4GR0A 2RJPA 5I4OA 3LJZA 4WK7A 1QJIA 4WKIA 4GUYA 1KUKA 4H2EA 3DNGA 4I03A 2MZHA 2J0TA 4JP4A 4XCTA 4L6TA 3DL1A 1ZS0A 1ATLA 1PWWA 2W13A 3O2XA 4AUOA 4GR8A 3HBUP 3ELMA 3EHYA 1FBLA 3NX7A 5I2ZA 1OS9A 3AYUA 1JAPA 2D1OA 1A86A 1JK3A 1HTDA 2V4BA 1ND1A 1XURA 2W12A 4ON1A 3WV3A 1BUDA 2JSDA 4PKRA 3DPFA 1H71P 1RMZA 4AXQA 1IACA 1K7QA 3OHOA 3HY7A 1L6JA 3LUNA 3F15A 1B8YA 2KRJA 4GWNA 3UVCA 1O0QA 1JJ9A 1PWUA 1S4BP 1BM6A 2X3AA 1KAPP 2FV9A 1ZTQA 1D8FA 4ZR5A 3Q2GA 1AYKA 3HY9A 5LABA 3F17A 1D7XA 2OW1A
chains in the Genus database with same CATH superfamily
1QUAA 1KUIA 3HDBA 1DMTA 1RM8A 3G5CA 1MMBA 1OZ9A 4PKUA 1FLSA 1B3DA 3KRYA 2YUFA 3EDZA 3DSLA 1ROSA 3TT4A 3Q2HA 1OS2A 1MNCA 1AF0A 3TSKA 3L0TA 1C7KA 2MZIA 1KUGA 4IJOA 1Q3AA 2AYKA 2WO9A 3SHIA 3B8ZA 3TS4A 2I47A 5CXAA 3USNA 1J7NA 1XFXA 1XFZA 1BKCA 1ZXVA 2RJQA 3LQ0A 2QPJA 5D1SA 3LK8A 5D3CA 2DW1A 1I76A 5B5PA 2YIGA 3KEKA 1TVIA 1Y0VA 1BUVM 5D1UA 3MA2A 1HFSA 1I1IP 4JA1A 4CTHA 2POJA 5JMYA 4IN9A 2HU6A 1MMPA 2WO8A 2K9CA 2DW0A 1IADA 3F18A 3HB2P 1HY7A 4AIGA 2OZRA 2AIGP 4HX3A 4XBHA 2ERQA 3B2ZA 3WV1A 3O64A 2Y6CA 3KHIA 1ASTA 1BQQM 1G05A 2JT6A 1DTHA 1AKLA 5B5OA 3ZVSA 5BPAA 5D7WA 1YQYA 2A8HA 1HV5A 5CZMA 3ZXHA 3E8RA 1IAEA 1SLMA 3LIKA 2X3CA 3KEJA 3WV2A 4PKVA 1Y93A 2CKIA 1Y8JA 1YCMA 3DTIA 4I35A 2OVZA 1MMQA 4DD8A 4H76A 1UEAA 4GWMA 2D1NA 1SATA 4G0DA 1QJJA 1PWPA 1CAQA 1IAAA 4H49A 3LMCA 4FVLA 1D5JA 1YP1A 2JT5A 1SU3A 1XM5A 1OM6A 2L0RA 1IABA 1JH1A 3G42A 3GBOA 1ZXCA 3RTSA 1GE6A 4H3XA 1QIAA 1CGLA 3K7NA 5BOTA 1R1JA 1JANA 1IAGA 1JAOA 3AYKA 3LQBA 1SMPA 1MMRA 3KECA 1K7GA 4A3WA 1Z3JA 1ZP5A 3N2UA 1USNA 4G9LA 4WZVA 2ERPA 2WOAA 1BKCE 1YOUA 4WF6A 3OHLA 4FXQA 3K7LA 2K2GA 2Z2DA 3B92A 2EROA 5I43A 3CKIA 1D8MA 1BIWA 2W15A 3N2VA 4PKQA 3P1VA 1BKCI 2N8RA 3KWVC 4GF1A 1G9KA 3LKAA 2OI0A 2TCLA 1CK7A 1XUCA 3KMEA 4QKZA 3DPEA 1C8TA 1OMJA 3HBVP 3HYGA 4ILWD 4JIJA 4A7BA 2XS3A 4EFSA 4H1QA 1XFYA 3EDGA 5CUHA 966CA 3LILA 1R1HA 4XM6A 4L19A 1A85A 4WKEA 2W14A 5L7FA 4GQLA 1G4KA 1GKCA 1EAKA 2DDFA 1GKDA 2OW0A 3EDIA 5D2BA 3HDAP 3ZUKA 1I73A 5L79A 4JPAA 1UMTA 1BQOA 1JIWP 3DWBA 3LEAA 1BZSA 1C3IA 2W0DA 4Q1LA 3LJGA 3BA0A 4JQGA 3VTGA 1XUDA 456CA 1R55A 1JIZA 1K7IA 2X3BA 4DV8A 1GE7A 1OM8A 1JKYA 4DF9A 1UMSA 5I12A 4IUWA 3LJTA 3DTKA 5I0LA 2MZEA 4AYKA 1WNIA 1HFCA 2JIHA 3AIGA 3LIRA 1OM7A 2PJTA 1GE5A 2FV5A 4R3VA 3RTTA 1OO9A 2YB9A 2USNA 4FXYP 4PKTA 1EUBA 1R1IA 2OXUA 4L63A 1R54A 5H8XA 4GR3A 4FU4A 2MLRA 4XM8A 2O36A 3F1AA 3VI1A 1GXDA 1JAQA 2DDYA 4DPEA 2XS4A 1PWQA 4J4MA 2OXWA 1CXVA 5I3MA 4XM7A 1HOVA 3KMCA 1SLNA 5BOYA 2E2DA 2MLSA 1ZVXA 2CLTA 1GO8P 3EHXA 3F19A 4L7AA 1O0TA 3LE9A 1GO7P 4PKWA 1XFWA 2DW2A 2X7MA 2O3EA 1KUFA 3EWJA 5D1TA 1EB6A 1PWVA 3V96B 2JNPA 1KBCA 1CGFA 1CIZA 2OXZA 1G49A 3LGPA 3L0VA 3F16A 1QIBA 1FM1A 1CQRA 3U1RA 3EDHA 1CGEA 4H30A 3LUMA 1UTTA 1QICA 4H82A 1XFUA 2E3XA 4PKSA 1KUHA 1XFVA 1SRPA 2OW9A 1BSWA 2SRTA 2OVXA 1UTZA 2Y6DA 4HMAA 3DTEA 1XAXA 3TVCA 3I7IA 3I7GA 3P24A 4H84A 2J83A 2OW2A 2OY4A 2OY2A 1G12A 830CA 4GR0A 2RJPA 5I4OA 3LJZA 4WK7A 1QJIA 4WKIA 4GUYA 1KUKA 4H2EA 3DNGA 4I03A 2MZHA 2J0TA 4JP4A 4XCTA 4L6TA 3DL1A 1ZS0A 1ATLA 1PWWA 2W13A 3O2XA 4AUOA 4GR8A 3HBUP 3ELMA 3EHYA 1FBLA 3NX7A 5I2ZA 1OS9A 3AYUA 1JAPA 2D1OA 1A86A 1JK3A 1HTDA 2V4BA 1ND1A 1XURA 2W12A 4ON1A 3WV3A 1BUDA 2JSDA 4PKRA 3DPFA 1H71P 1RMZA 4AXQA 1IACA 1K7QA 3OHOA 3HY7A 1L6JA 3LUNA 3F15A 1B8YA 2KRJA 4GWNA 3UVCA 1O0QA 1JJ9A 1PWUA 1S4BP 1BM6A 2X3AA 1KAPP 2FV9A 1ZTQA 1D8FA 4ZR5A 3Q2GA 1AYKA 3HY9A 5LABA 3F17A 1D7XA 2OW1A
chains in the Genus database with same CATH topology
1QUAA 1KUIA 3HDBA 1DMTA 1RM8A 3G5CA 1MMBA 4PKUA 1FLSA 1B3DA 3KRYA 2YUFA 3EDZA 3DSLA 1ROSA 3TT4A 3Q2HA 1OS2A 1MNCA 1AF0A 3TSKA 3L0TA 1C7KA 2MZIA 1KUGA 4IJOA 1Q3AA 2AYKA 2WO9A 3SHIA 3B8ZA 3TS4A 2I47A 5CXAA 3USNA 1J7NA 1XFXA 1XFZA 1BKCA 1ZXVA 2RJQA 3LQ0A 2QPJA 5D1SA 3LK8A 5D3CA 2DW1A 1I76A 5B5PA 2YIGA 3KEKA 1Y0VA 1BUVM 5D1UA 3MA2A 1HFSA 1I1IP 4JA1A 4CTHA 2POJA 5JMYA 4IN9A 2HU6A 1MMPA 2WO8A 2K9CA 2DW0A 1IADA 3F18A 3HB2P 1HY7A 4AIGA 2OZRA 2AIGP 4HX3A 4XBHA 2ERQA 3B2ZA 3WV1A 3O64A 2Y6CA 3KHIA 1ASTA 1BQQM 1G05A 2JT6A 1DTHA 1AKLA 5B5OA 3ZVSA 5BPAA 5D7WA 1YQYA 2A8HA 1HV5A 5CZMA 3ZXHA 3E8RA 1IAEA 1SLMA 3LIKA 2X3CA 3KEJA 3WV2A 4PKVA 1Y93A 2CKIA 1Y8JA 1YCMA 3DTIA 4I35A 2OVZA 1MMQA 4DD8A 4H76A 1UEAA 4GWMA 2D1NA 1SATA 4G0DA 1QJJA 1PWPA 1CAQA 1IAAA 4H49A 3LMCA 4FVLA 1D5JA 1YP1A 2JT5A 1SU3A 1OM6A 2L0RA 1IABA 1JH1A 3G42A 3GBOA 1ZXCA 3RTSA 1GE6A 4H3XA 1QIAA 1CGLA 3K7NA 5BOTA 1R1JA 1JANA 1IAGA 1JAOA 3AYKA 3LQBA 1SMPA 1MMRA 3KECA 1K7GA 4A3WA 1Z3JA 1ZP5A 3N2UA 1USNA 4G9LA 4WZVA 2ERPA 2WOAA 1BKCE 1YOUA 4WF6A 3OHLA 4FXQA 3K7LA 2K2GA 2Z2DA 3B92A 2EROA 5I43A 3CKIA 1D8MA 1BIWA 2W15A 3N2VA 4PKQA 3P1VA 1BKCI 2N8RA 3KWVC 4GF1A 1G9KA 3LKAA 2OI0A 2TCLA 1CK7A 1XUCA 3KMEA 4QKZA 3DPEA 1C8TA 1OMJA 3HBVP 3HYGA 4ILWD 4JIJA 4A7BA 2XS3A 4EFSA 4H1QA 1XFYA 3EDGA 5CUHA 966CA 3LILA 1R1HA 4XM6A 4L19A 1A85A 4WKEA 2W14A 5L7FA 4GQLA 1G4KA 1GKCA 1EAKA 2DDFA 1GKDA 2OW0A 3EDIA 5D2BA 3HDAP 3ZUKA 1I73A 5L79A 4JPAA 1UMTA 1BQOA 1JIWP 3DWBA 3LEAA 1BZSA 1C3IA 2W0DA 4Q1LA 3LJGA 3BA0A 4JQGA 3VTGA 1XUDA 456CA 1R55A 1JIZA 1K7IA 2X3BA 4DV8A 1GE7A 1OM8A 1JKYA 4DF9A 1UMSA 5I12A 4IUWA 3LJTA 3DTKA 5I0LA 2MZEA 4AYKA 1WNIA 1HFCA 2JIHA 3AIGA 3LIRA 1OM7A 2PJTA 1GE5A 2FV5A 4R3VA 3RTTA 1OO9A 2YB9A 2USNA 4FXYP 4PKTA 1EUBA 1R1IA 2OXUA 4L63A 1R54A 5H8XA 4GR3A 4FU4A 2MLRA 4XM8A 2O36A 3F1AA 3VI1A 1GXDA 1JAQA 2DDYA 4DPEA 2XS4A 1PWQA 4J4MA 2OXWA 1CXVA 5I3MA 4XM7A 1HOVA 3KMCA 1SLNA 5BOYA 2E2DA 2MLSA 1ZVXA 2CLTA 1GO8P 3EHXA 3F19A 4L7AA 1O0TA 3LE9A 1GO7P 4PKWA 1XFWA 2DW2A 2X7MA 2O3EA 1KUFA 3EWJA 5D1TA 1EB6A 1PWVA 3V96B 2JNPA 1KBCA 1CGFA 1CIZA 2OXZA 1G49A 3LGPA 3L0VA 3F16A 1QIBA 1FM1A 1CQRA 3U1RA 3EDHA 1CGEA 4H30A 3LUMA 1UTTA 1QICA 4H82A 1XFUA 2E3XA 4PKSA 1KUHA 1XFVA 1SRPA 2OW9A 1BSWA 2SRTA 2OVXA 1UTZA 2Y6DA 4HMAA 3DTEA 3TVCA 3I7IA 3I7GA 3P24A 4H84A 2J83A 2OW2A 2OY4A 2OY2A 1G12A 830CA 4GR0A 2RJPA 5I4OA 3LJZA 4WK7A 1QJIA 4WKIA 4GUYA 1KUKA 4H2EA 3DNGA 4I03A 2MZHA 2J0TA 4JP4A 4XCTA 4L6TA 3DL1A 1ZS0A 1ATLA 1PWWA 2W13A 3O2XA 4AUOA 4GR8A 3HBUP 3ELMA 3EHYA 1FBLA 3NX7A 5I2ZA 1OS9A 3AYUA 1JAPA 2D1OA 1A86A 1JK3A 1HTDA 2V4BA 1ND1A 1XURA 2W12A 4ON1A 3WV3A 1BUDA 2JSDA 4PKRA 3DPFA 1H71P 1RMZA 4AXQA 1IACA 1K7QA 3OHOA 3HY7A 1L6JA 3LUNA 3F15A 1B8YA 2KRJA 4GWNA 3UVCA 1O0QA 1JJ9A 1PWUA 1S4BP 1BM6A 2X3AA 1KAPP 2FV9A 1ZTQA 1D8FA 4ZR5A 3Q2GA 1AYKA 3HY9A 5LABA 3F17A 1D7XA 2OW1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QUA A;  1KUI A;  3HDB A;  1DMT A;  1RM8 A;  3G5C A;  1MMB A;  4PKU A;  1FLS A;  1B3D A;  3KRY A;  3EDZ A;  3DSL A;  1ROS A;  3TT4 A;  3Q2H A;  1OS2 A;  1MNC A;  1AF0 A;  3TSK A;  3L0T A;  1C7K A;  2MZI A;  1KUG A;  4IJO A;  1Q3A A;  2AYK A;  2WO9 A;  3SHI A;  3B8Z A;  3TS4 A;  2I47 A;  5CXA A;  3USN A;  1J7N A;  1XFX A;  1XFZ A;  1BKC A;  1ZXV A;  2RJQ A;  3LQ0 A;  2QPJ A;  5D1S A;  3LK8 A;  5D3C A;  2DW1 A;  1I76 A;  5B5P A;  2YIG A;  3KEK A;  1Y0V A;  1BUV M;  5D1U A;  3MA2 A;  1HFS A;  1I1I P;  4JA1 A;  4CTH A;  2POJ A;  5JMY A;  4IN9 A;  2HU6 A;  1MMP A;  2WO8 A;  2K9C A;  2DW0 A;  1IAD A;  3F18 A;  3HB2 P;  1HY7 A;  4AIG A;  2OZR A;  2AIG P;  4HX3 A;  4XBH A;  2ERQ A;  3B2Z A;  3WV1 A;  3O64 A;  2Y6C A;  3KHI A;  1AST A;  1BQQ M;  1G05 A;  2JT6 A;  1DTH A;  1AKL A;  5B5O A;  3ZVS A;  5BPA A;  5D7W A;  1YQY A;  2A8H A;  1HV5 A;  5CZM A;  3ZXH A;  3E8R A;  1IAE A;  1SLM A;  3LIK A;  2X3C A;  3KEJ A;  3WV2 A;  4PKV A;  1Y93 A;  2CKI A;  1Y8J A;  1YCM A;  4I35 A;  2OVZ A;  1MMQ A;  4DD8 A;  4H76 A;  1UEA A;  4GWM A;  2D1N A;  1SAT A;  4G0D A;  1QJJ A;  1PWP A;  1CAQ A;  1IAA A;  4H49 A;  3LMC A;  4FVL A;  1D5J A;  1YP1 A;  2JT5 A;  1SU3 A;  1OM6 A;  2L0R A;  1IAB A;  1JH1 A;  3G42 A;  3GBO A;  1ZXC A;  3RTS A;  1GE6 A;  4H3X A;  1QIA A;  1CGL A;  3K7N A;  5BOT A;  1R1J A;  1JAN A;  1IAG A;  1JAO A;  3AYK A;  3LQB A;  1SMP A;  1MMR A;  3KEC A;  1K7G A;  4A3W A;  1Z3J A;  1ZP5 A;  3N2U A;  1USN A;  4G9L A;  4WZV A;  2ERP A;  2WOA A;  1BKC E;  1YOU A;  4WF6 A;  3OHL A;  4FXQ A;  3K7L A;  2K2G A;  2Z2D A;  3B92 A;  2ERO A;  5I43 A;  3CKI A;  1D8M A;  1BIW A;  2W15 A;  3N2V A;  4PKQ A;  3P1V A;  1BKC I;  2N8R A;  3KWV C;  4GF1 A;  1G9K A;  3LKA A;  2OI0 A;  2TCL A;  1CK7 A;  1XUC A;  3KME A;  4QKZ A;  3DPE A;  1C8T A;  1OMJ A;  3HBV P;  3HYG A;  4ILW D;  4JIJ A;  4A7B A;  2XS3 A;  4EFS A;  4H1Q A;  1XFY A;  3EDG A;  5CUH A;  966C A;  3LIL A;  1R1H A;  4XM6 A;  4L19 A;  1A85 A;  4WKE A;  2W14 A;  5L7F A;  4GQL A;  1G4K A;  1GKC A;  1EAK A;  2DDF A;  1GKD A;  2OW0 A;  3EDI A;  5D2B A;  3HDA P;  3ZUK A;  1I73 A;  5L79 A;  4JPA A;  1UMT A;  1BQO A;  1JIW P;  3DWB A;  3LEA A;  1BZS A;  1C3I A;  2W0D A;  4Q1L A;  3LJG A;  3BA0 A;  4JQG A;  3VTG A;  1XUD A;  456C A;  1R55 A;  1JIZ A;  1K7I A;  2X3B A;  4DV8 A;  1GE7 A;  1OM8 A;  1JKY A;  4DF9 A;  1UMS A;  5I12 A;  4IUW A;  3LJT A;  5I0L A;  2MZE A;  4AYK A;  1WNI A;  1HFC A;  2JIH A;  3AIG A;  3LIR A;  1OM7 A;  2PJT A;  1GE5 A;  2FV5 A;  4R3V A;  3RTT A;  1OO9 A;  2YB9 A;  2USN A;  4FXY P;  4PKT A;  1EUB A;  1R1I A;  2OXU A;  4L63 A;  1R54 A;  5H8X A;  4GR3 A;  4FU4 A;  2MLR A;  4XM8 A;  2O36 A;  3F1A A;  3VI1 A;  1GXD A;  1JAQ A;  2DDY A;  4DPE A;  2XS4 A;  1PWQ A;  4J4M A;  2OXW A;  1CXV A;  5I3M A;  4XM7 A;  1HOV A;  3KMC A;  1SLN A;  5BOY A;  2E2D A;  2MLS A;  1ZVX A;  2CLT A;  1GO8 P;  3EHX A;  3F19 A;  1O0T A;  3LE9 A;  1GO7 P;  4PKW A;  1XFW A;  2DW2 A;  2X7M A;  2O3E A;  1KUF A;  3EWJ A;  5D1T A;  1EB6 A;  1PWV A;  3V96 B;  2JNP A;  1KBC A;  1CGF A;  1CIZ A;  2OXZ A;  1G49 A;  3LGP A;  3L0V A;  3F16 A;  1QIB A;  1FM1 A;  1CQR A;  3U1R A;  3EDH A;  1CGE A;  4H30 A;  3LUM A;  1UTT A;  1QIC A;  4H82 A;  1XFU A;  2E3X A;  4PKS A;  1KUH A;  1XFV A;  1SRP A;  2OW9 A;  1BSW A;  2SRT A;  2OVX A;  1UTZ A;  2Y6D A;  4HMA A;  3TVC A;  3I7I A;  3I7G A;  3P24 A;  4H84 A;  2J83 A;  2OW2 A;  2OY4 A;  2OY2 A;  1G12 A;  830C A;  4GR0 A;  2RJP A;  5I4O A;  3LJZ A;  4WK7 A;  1QJI A;  4WKI A;  4GUY A;  1KUK A;  4H2E A;  3DNG A;  4I03 A;  2MZH A;  2J0T A;  4JP4 A;  4XCT A;  4L6T A;  3DL1 A;  1ZS0 A;  1ATL A;  1PWW A;  2W13 A;  3O2X A;  4AUO A;  4GR8 A;  3HBU P;  3ELM A;  3EHY A;  1FBL A;  3NX7 A;  5I2Z A;  1OS9 A;  3AYU A;  1JAP A;  2D1O A;  1A86 A;  1JK3 A;  1HTD A;  2V4B A;  1ND1 A;  1XUR A;  2W12 A;  4ON1 A;  3WV3 A;  1BUD A;  2JSD A;  4PKR A;  3DPF A;  1H71 P;  1RMZ A;  4AXQ A;  1IAC A;  1K7Q A;  3OHO A;  3HY7 A;  1L6J A;  3LUN A;  3F15 A;  1B8Y A;  2KRJ A;  4GWN A;  3UVC A;  1O0Q A;  1JJ9 A;  1PWU A;  1S4B P;  1BM6 A;  2X3A A;  1KAP P;  2FV9 A;  1ZTQ A;  1D8F A;  4ZR5 A;  3Q2G A;  1AYK A;  3HY9 A;  5LAB A;  3F17 A;  1D7X A;  2OW1 A; 
#chains in the Genus database with same CATH topology
 1QUA A;  1KUI A;  3HDB A;  1DMT A;  1RM8 A;  3G5C A;  1MMB A;  1OZ9 A;  4PKU A;  1FLS A;  1B3D A;  3KRY A;  2YUF A;  3EDZ A;  3DSL A;  1ROS A;  3TT4 A;  3Q2H A;  1OS2 A;  1MNC A;  1AF0 A;  3TSK A;  3L0T A;  1C7K A;  2MZI A;  1KUG A;  4IJO A;  1Q3A A;  2AYK A;  2WO9 A;  3SHI A;  3B8Z A;  3TS4 A;  2I47 A;  5CXA A;  3USN A;  1J7N A;  1XFX A;  1XFZ A;  1BKC A;  1ZXV A;  2RJQ A;  3LQ0 A;  2QPJ A;  5D1S A;  3LK8 A;  5D3C A;  2DW1 A;  1I76 A;  5B5P A;  2YIG A;  3KEK A;  1TVI A;  1Y0V A;  1BUV M;  5D1U A;  3MA2 A;  1HFS A;  1I1I P;  4JA1 A;  4CTH A;  2POJ A;  5JMY A;  4IN9 A;  2HU6 A;  1MMP A;  2WO8 A;  2K9C A;  2DW0 A;  1IAD A;  3F18 A;  3HB2 P;  1HY7 A;  4AIG A;  2OZR A;  2AIG P;  4HX3 A;  4XBH A;  2ERQ A;  3B2Z A;  3WV1 A;  3O64 A;  2Y6C A;  3KHI A;  1AST A;  1BQQ M;  1G05 A;  2JT6 A;  1DTH A;  1AKL A;  5B5O A;  3ZVS A;  5BPA A;  5D7W A;  1YQY A;  2A8H A;  1HV5 A;  5CZM A;  3ZXH A;  3E8R A;  1IAE A;  1SLM A;  3LIK A;  2X3C A;  3KEJ A;  3WV2 A;  4PKV A;  1Y93 A;  2CKI A;  1Y8J A;  1YCM A;  3DTI A;  4I35 A;  2OVZ A;  1MMQ A;  4DD8 A;  4H76 A;  1UEA A;  4GWM A;  2D1N A;  1SAT A;  4G0D A;  1QJJ A;  1PWP A;  1CAQ A;  1IAA A;  4H49 A;  3LMC A;  4FVL A;  1D5J A;  1YP1 A;  2JT5 A;  1SU3 A;  1XM5 A;  1OM6 A;  2L0R A;  1IAB A;  1JH1 A;  3G42 A;  3GBO A;  1ZXC A;  3RTS A;  1GE6 A;  4H3X A;  1QIA A;  1CGL A;  3K7N A;  5BOT A;  1R1J A;  1JAN A;  1IAG A;  1JAO A;  3AYK A;  3LQB A;  1SMP A;  1MMR A;  3KEC A;  1K7G A;  4A3W A;  1Z3J A;  1ZP5 A;  3N2U A;  1USN A;  4G9L A;  4WZV A;  2ERP A;  2WOA A;  1BKC E;  1YOU A;  4WF6 A;  3OHL A;  4FXQ A;  3K7L A;  2K2G A;  2Z2D A;  3B92 A;  2ERO A;  5I43 A;  3CKI A;  1D8M A;  1BIW A;  2W15 A;  3N2V A;  4PKQ A;  3P1V A;  1BKC I;  2N8R A;  3KWV C;  4GF1 A;  1G9K A;  3LKA A;  2OI0 A;  2TCL A;  1CK7 A;  1XUC A;  3KME A;  4QKZ A;  3DPE A;  1C8T A;  1OMJ A;  3HBV P;  3HYG A;  4ILW D;  4JIJ A;  4A7B A;  2XS3 A;  4EFS A;  4H1Q A;  1XFY A;  3EDG A;  5CUH A;  966C A;  3LIL A;  1R1H A;  4XM6 A;  4L19 A;  1A85 A;  4WKE A;  2W14 A;  5L7F A;  4GQL A;  1G4K A;  1GKC A;  1EAK A;  2DDF A;  1GKD A;  2OW0 A;  3EDI A;  5D2B A;  3HDA P;  3ZUK A;  1I73 A;  5L79 A;  4JPA A;  1UMT A;  1BQO A;  1JIW P;  3DWB A;  3LEA A;  1BZS A;  1C3I A;  2W0D A;  4Q1L A;  3LJG A;  3BA0 A;  4JQG A;  3VTG A;  1XUD A;  456C A;  1R55 A;  1JIZ A;  1K7I A;  2X3B A;  4DV8 A;  1GE7 A;  1OM8 A;  1JKY A;  4DF9 A;  1UMS A;  5I12 A;  4IUW A;  3LJT A;  3DTK A;  5I0L A;  2MZE A;  4AYK A;  1WNI A;  1HFC A;  2JIH A;  3AIG A;  3LIR A;  1OM7 A;  2PJT A;  1GE5 A;  2FV5 A;  4R3V A;  3RTT A;  1OO9 A;  2YB9 A;  2USN A;  4FXY P;  4PKT A;  1EUB A;  1R1I A;  2OXU A;  4L63 A;  1R54 A;  5H8X A;  4GR3 A;  4FU4 A;  2MLR A;  4XM8 A;  2O36 A;  3F1A A;  3VI1 A;  1GXD A;  1JAQ A;  2DDY A;  4DPE A;  2XS4 A;  1PWQ A;  4J4M A;  2OXW A;  1CXV A;  5I3M A;  4XM7 A;  1HOV A;  3KMC A;  1SLN A;  5BOY A;  2E2D A;  2MLS A;  1ZVX A;  2CLT A;  1GO8 P;  3EHX A;  3F19 A;  4L7A A;  1O0T A;  3LE9 A;  1GO7 P;  4PKW A;  1XFW A;  2DW2 A;  2X7M A;  2O3E A;  1KUF A;  3EWJ A;  5D1T A;  1EB6 A;  1PWV A;  3V96 B;  2JNP A;  1KBC A;  1CGF A;  1CIZ A;  2OXZ A;  1G49 A;  3LGP A;  3L0V A;  3F16 A;  1QIB A;  1FM1 A;  1CQR A;  3U1R A;  3EDH A;  1CGE A;  4H30 A;  3LUM A;  1UTT A;  1QIC A;  4H82 A;  1XFU A;  2E3X A;  4PKS A;  1KUH A;  1XFV A;  1SRP A;  2OW9 A;  1BSW A;  2SRT A;  2OVX A;  1UTZ A;  2Y6D A;  4HMA A;  3DTE A;  1XAX A;  3TVC A;  3I7I A;  3I7G A;  3P24 A;  4H84 A;  2J83 A;  2OW2 A;  2OY4 A;  2OY2 A;  1G12 A;  830C A;  4GR0 A;  2RJP A;  5I4O A;  3LJZ A;  4WK7 A;  1QJI A;  4WKI A;  4GUY A;  1KUK A;  4H2E A;  3DNG A;  4I03 A;  2MZH A;  2J0T A;  4JP4 A;  4XCT A;  4L6T A;  3DL1 A;  1ZS0 A;  1ATL A;  1PWW A;  2W13 A;  3O2X A;  4AUO A;  4GR8 A;  3HBU P;  3ELM A;  3EHY A;  1FBL A;  3NX7 A;  5I2Z A;  1OS9 A;  3AYU A;  1JAP A;  2D1O A;  1A86 A;  1JK3 A;  1HTD A;  2V4B A;  1ND1 A;  1XUR A;  2W12 A;  4ON1 A;  3WV3 A;  1BUD A;  2JSD A;  4PKR A;  3DPF A;  1H71 P;  1RMZ A;  4AXQ A;  1IAC A;  1K7Q A;  3OHO A;  3HY7 A;  1L6J A;  3LUN A;  3F15 A;  1B8Y A;  2KRJ A;  4GWN A;  3UVC A;  1O0Q A;  1JJ9 A;  1PWU A;  1S4B P;  1BM6 A;  2X3A A;  1KAP P;  2FV9 A;  1ZTQ A;  1D8F A;  4ZR5 A;  3Q2G A;  1AYK A;  3HY9 A;  5LAB A;  3F17 A;  1D7X A;  2OW1 A; 
#chains in the Genus database with same CATH homology
 1QUA A;  1KUI A;  3HDB A;  1DMT A;  1RM8 A;  3G5C A;  1MMB A;  4PKU A;  1FLS A;  1B3D A;  3KRY A;  2YUF A;  3EDZ A;  3DSL A;  1ROS A;  3TT4 A;  3Q2H A;  1OS2 A;  1MNC A;  1AF0 A;  3TSK A;  3L0T A;  1C7K A;  2MZI A;  1KUG A;  4IJO A;  1Q3A A;  2AYK A;  2WO9 A;  3SHI A;  3B8Z A;  3TS4 A;  2I47 A;  5CXA A;  3USN A;  1J7N A;  1XFX A;  1XFZ A;  1BKC A;  1ZXV A;  2RJQ A;  3LQ0 A;  2QPJ A;  5D1S A;  3LK8 A;  5D3C A;  2DW1 A;  1I76 A;  5B5P A;  2YIG A;  3KEK A;  1Y0V A;  1BUV M;  5D1U A;  3MA2 A;  1HFS A;  1I1I P;  4JA1 A;  4CTH A;  2POJ A;  5JMY A;  4IN9 A;  2HU6 A;  1MMP A;  2WO8 A;  2K9C A;  2DW0 A;  1IAD A;  3F18 A;  3HB2 P;  1HY7 A;  4AIG A;  2OZR A;  2AIG P;  4HX3 A;  4XBH A;  2ERQ A;  3B2Z A;  3WV1 A;  3O64 A;  2Y6C A;  3KHI A;  1AST A;  1BQQ M;  1G05 A;  2JT6 A;  1DTH A;  1AKL A;  5B5O A;  3ZVS A;  5BPA A;  5D7W A;  1YQY A;  2A8H A;  1HV5 A;  5CZM A;  3ZXH A;  3E8R A;  1IAE A;  1SLM A;  3LIK A;  2X3C A;  3KEJ A;  3WV2 A;  4PKV A;  1Y93 A;  2CKI A;  1Y8J A;  1YCM A;  3DTI A;  4I35 A;  2OVZ A;  1MMQ A;  4DD8 A;  4H76 A;  1UEA A;  4GWM A;  2D1N A;  1SAT A;  4G0D A;  1QJJ A;  1PWP A;  1CAQ A;  1IAA A;  4H49 A;  3LMC A;  4FVL A;  1D5J A;  1YP1 A;  2JT5 A;  1SU3 A;  1OM6 A;  2L0R A;  1IAB A;  1JH1 A;  3G42 A;  3GBO A;  1ZXC A;  3RTS A;  1GE6 A;  4H3X A;  1QIA A;  1CGL A;  3K7N A;  5BOT A;  1R1J A;  1JAN A;  1IAG A;  1JAO A;  3AYK A;  3LQB A;  1SMP A;  1MMR A;  3KEC A;  1K7G A;  4A3W A;  1Z3J A;  1ZP5 A;  3N2U A;  1USN A;  4G9L A;  4WZV A;  2ERP A;  2WOA A;  1BKC E;  1YOU A;  4WF6 A;  3OHL A;  4FXQ A;  3K7L A;  2K2G A;  2Z2D A;  3B92 A;  2ERO A;  5I43 A;  3CKI A;  1D8M A;  1BIW A;  2W15 A;  3N2V A;  4PKQ A;  3P1V A;  1BKC I;  2N8R A;  3KWV C;  4GF1 A;  1G9K A;  3LKA A;  2OI0 A;  2TCL A;  1CK7 A;  1XUC A;  3KME A;  4QKZ A;  3DPE A;  1C8T A;  1OMJ A;  3HBV P;  3HYG A;  4ILW D;  4JIJ A;  4A7B A;  2XS3 A;  4EFS A;  4H1Q A;  1XFY A;  3EDG A;  5CUH A;  966C A;  3LIL A;  1R1H A;  4XM6 A;  4L19 A;  1A85 A;  4WKE A;  2W14 A;  5L7F A;  4GQL A;  1G4K A;  1GKC A;  1EAK A;  2DDF A;  1GKD A;  2OW0 A;  3EDI A;  5D2B A;  3HDA P;  3ZUK A;  1I73 A;  5L79 A;  4JPA A;  1UMT A;  1BQO A;  1JIW P;  3DWB A;  3LEA A;  1BZS A;  1C3I A;  2W0D A;  4Q1L A;  3LJG A;  3BA0 A;  4JQG A;  3VTG A;  1XUD A;  456C A;  1R55 A;  1JIZ A;  1K7I A;  2X3B A;  4DV8 A;  1GE7 A;  1OM8 A;  1JKY A;  4DF9 A;  1UMS A;  5I12 A;  4IUW A;  3LJT A;  3DTK A;  5I0L A;  2MZE A;  4AYK A;  1WNI A;  1HFC A;  2JIH A;  3AIG A;  3LIR A;  1OM7 A;  2PJT A;  1GE5 A;  2FV5 A;  4R3V A;  3RTT A;  1OO9 A;  2YB9 A;  2USN A;  4FXY P;  4PKT A;  1EUB A;  1R1I A;  2OXU A;  4L63 A;  1R54 A;  5H8X A;  4GR3 A;  4FU4 A;  2MLR A;  4XM8 A;  2O36 A;  3F1A A;  3VI1 A;  1GXD A;  1JAQ A;  2DDY A;  4DPE A;  2XS4 A;  1PWQ A;  4J4M A;  2OXW A;  1CXV A;  5I3M A;  4XM7 A;  1HOV A;  3KMC A;  1SLN A;  5BOY A;  2E2D A;  2MLS A;  1ZVX A;  2CLT A;  1GO8 P;  3EHX A;  3F19 A;  4L7A A;  1O0T A;  3LE9 A;  1GO7 P;  4PKW A;  1XFW A;  2DW2 A;  2X7M A;  2O3E A;  1KUF A;  3EWJ A;  5D1T A;  1EB6 A;  1PWV A;  3V96 B;  2JNP A;  1KBC A;  1CGF A;  1CIZ A;  2OXZ A;  1G49 A;  3LGP A;  3L0V A;  3F16 A;  1QIB A;  1FM1 A;  1CQR A;  3U1R A;  3EDH A;  1CGE A;  4H30 A;  3LUM A;  1UTT A;  1QIC A;  4H82 A;  1XFU A;  2E3X A;  4PKS A;  1KUH A;  1XFV A;  1SRP A;  2OW9 A;  1BSW A;  2SRT A;  2OVX A;  1UTZ A;  2Y6D A;  4HMA A;  3DTE A;  3TVC A;  3I7I A;  3I7G A;  3P24 A;  4H84 A;  2J83 A;  2OW2 A;  2OY4 A;  2OY2 A;  1G12 A;  830C A;  4GR0 A;  2RJP A;  5I4O A;  3LJZ A;  4WK7 A;  1QJI A;  4WKI A;  4GUY A;  1KUK A;  4H2E A;  3DNG A;  4I03 A;  2MZH A;  2J0T A;  4JP4 A;  4XCT A;  4L6T A;  3DL1 A;  1ZS0 A;  1ATL A;  1PWW A;  2W13 A;  3O2X A;  4AUO A;  4GR8 A;  3HBU P;  3ELM A;  3EHY A;  1FBL A;  3NX7 A;  5I2Z A;  1OS9 A;  3AYU A;  1JAP A;  2D1O A;  1A86 A;  1JK3 A;  1HTD A;  2V4B A;  1ND1 A;  1XUR A;  2W12 A;  4ON1 A;  3WV3 A;  1BUD A;  2JSD A;  4PKR A;  3DPF A;  1H71 P;  1RMZ A;  4AXQ A;  1IAC A;  1K7Q A;  3OHO A;  3HY7 A;  1L6J A;  3LUN A;  3F15 A;  1B8Y A;  2KRJ A;  4GWN A;  3UVC A;  1O0Q A;  1JJ9 A;  1PWU A;  1S4B P;  1BM6 A;  2X3A A;  1KAP P;  2FV9 A;  1ZTQ A;  1D8F A;  4ZR5 A;  3Q2G A;  1AYK A;  3HY9 A;  5LAB A;  3F17 A;  1D7X A;  2OW1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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