2A8HA

Crystal structure of catalytic domain of tace with thiomorpholine sulfonamide hydroxamate inhibitor
Total Genus 84
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
259
structure length
259
Chain Sequence
DPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Acetylenic TACE inhibitors. Part 3: Thiomorpholine sulfonamide hydroxamates.
pubmed doi rcsb
molecule keywords ADAM 17
molecule tags Hydrolase
source organism Homo sapiens
total genus 84
structure length 259
sequence length 259
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2005-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2a8hA00
4ON1A 1BM6A 4HMAA 1KUHA 2O36A 1OMJA 3N2VA 1CAQA 1Y8JA 3LJGA 2AYKA 1JK3A 1UEAA 2RJPA 1FBLA 1XFUA 1R1JA 1SLMA 3U1RA 1CQRA 3HY7A 2JSDA 3EDHA 4H49A 3VTGA 3L0TA 3LJZA 4ILWD 1JAOA 5D1UA 4PKWA 1BKCI 1HY7A 3O64A 3LUMA 1BKCA 3KEJA 2DDYA 1G05A 3F19A 1IADA 1MNCA 1BKCE 1SLNA 3ZXHA 5LABA 3F15A 3LGPA 1G4KA 3O2XA 2Z2DA 4H2EA 1JANA 4H1QA 1USNA 4H3XA 4JA1A 1MMBA 1BZSA 4PKSA 1JIWP 1MMRA 2ERPA 1UMSA 1I73A 3EDZA 1PWPA 1QUAA 5I43A 3F18A 3WV3A 5I0LA 4XM8A 3LMCA 4G9LA 3TVCA 1A86A 1OO9A 1ROSA 2E2DA 1MMQA 1GE6A 3WV2A 2O3EA 1YOUA 4R3VA 3RTSA 1I76A 1GO7P 3ELMA 3DSLA 5I2ZA 1BSWA 1HV5A 5I4OA 3MA2A 1UMTA 1O0QA 3USNA 4PKQA 4EFSA 3EDIA 1SU3A 1QJJA 4JP4A 3HBVP 4FXYP 2K2GA 3GBOA 4HX3A 5BOTA 3Q2HA 2MZEA 2USNA 2X3AA 4PKRA 1R1HA 1FM1A 4PKTA 3EWJA 2D1OA 3LUNA 1WNIA 1C8TA 1KUKA 4DD8A 2AIGP 3I7GA 2OW9A 4WKEA 2POJA 1CGEA 4G0DA 1BUVM 4XBHA 3EHYA 1AYKA 3HDAP 5BOYA 4H82A 5L79A 3EDGA 2V4BA 1S4BP 1YCMA 1QIAA 2ERQA 4QKZA 1D7XA 1AF0A 1HFCA 2X7MA 1BQOA 4DPEA 4JQGA 5D2BA 1A85A 2MZIA 3KHIA 3LE9A 1XUDA 4AIGA 5I12A 3TT4A 2W15A 3LKAA 3KRYA 1IABA 3HY9A 4DV8A 1AKLA 1QJIA 4IUWA 2YIGA 1CGLA 1JAPA 3F17A 1XFVA 2E3XA 1Y0VA 4WKIA 3LJTA 2CKIA 1ZP5A 3EHXA 1KUGA 1ATLA 4GR0A 1ASTA 3WV1A 3ZVSA 2X3BA 2J83A 3P1VA 2FV9A 1JH1A 1PWUA 4GWMA 2FV5A 5D1SA 3ZUKA 5H8XA 3LQ0A 2MLSA 1BQQM 3DPFA 4JPAA 2D1NA 1CK7A 3NX7A 3Q2GA 1JAQA 1SRPA 2OI0A 3LK8A 1YQYA 2KRJA 4FVLA 1CXVA 2SRTA 3LEAA 5L7FA 1I1IP 2N8RA 4WK7A 2JIHA 456CA 3AYKA 2JNPA 1O0TA 2W0DA 3B92A 2OXWA 2JT5A 1D5JA 1G9KA 4I03A 4Q1LA 1XFZA 1XFWA 1B3DA 4ZR5A 2L0RA 1Q3AA 4DF9A 2OW0A 3OHOA 1K7GA 3AYUA 966CA 1DMTA 1XURA 1Y93A 1B8YA 1K7QA 4WZVA 4XM6A 4GWNA 1BIWA 5CUHA 1K7IA 2W12A 2XS3A 4GF1A 1GE5A 3AIGA 4J4MA 2WO9A 1UTTA 2OY4A 1R54A 1JJ9A 4H76A 3DWBA 2W13A 3L0VA 4GR3A 4L6TA 3K7NA 3LIRA 1EAKA 3DNGA 1G49A 1C3IA 1KUFA 1HFSA 1PWWA 3TSKA 3HBUP 2W14A 3E8RA 2X3CA 2A8HA 2OXUA 4CTHA 1JIZA 3RTTA 2XS4A 3KEKA 1OM8A 2OW2A 1KBCA 1RMZA 1ZVXA 1SMPA 1KUIA 1JKYA 4A3WA 3DL1A 3G5CA 2OW1A 1IAAA 1XFYA 2Y6CA 3LIKA 2OVZA 1R55A 3KMEA 3N2UA 2K9CA 3KWVC 5BPAA 1ZXCA 2OVXA 2QPJA 1J7NA 1BUDA 1PWVA 1RM8A 3CKIA 4GUYA 1R1IA 3F16A 1IAGA 4XM7A 2OXZA 4H30A 1H71P 1OS9A 3HB2P 2CLTA 1IACA 1D8FA 4IN9A 2WOAA 1Z3JA 3LILA 2OY2A 2MZHA 5D1TA 2RJQA 1QICA 5B5PA 3DPEA 2YB9A 1SATA 1DTHA 2DW2A 3LQBA 4GQLA 4L19A 2HU6A 2WO8A 3VI1A 4XCTA 2DW1A 1L6JA 4I35A 1HTDA 4H84A 5CZMA 3BA0A 1OS2A 1XFXA 5D7WA 1UTZA 3P24A 4FXQA 3SHIA 4A7BA 2Y6DA 4L63A 1D8MA 1QIBA 3TS4A 5I3MA 2PJTA 830CA 4GR8A 1FLSA 5CXAA 4AUOA 1XUCA 2DDFA 3G42A 2JT6A 4AXQA 5JMYA 1IAEA 1ZXVA 3HYGA 2OZRA 1ZS0A 3F1AA 3HDBA 3B2ZA 1PWQA 1OM7A 3UVCA 1G12A 1OM6A 2MLRA 2J0TA 1MMPA 1GKCA 2EROA 1HOVA 2I47A 4AYKA 3V96B 2TCLA 2DW0A 1C7KA 1YP1A 4FU4A 3K7LA 3KECA 4JIJA 3KMCA 1GE7A 3B8ZA 5D3CA 4PKUA 1KAPP 4PKVA 4IJOA 1GXDA 1CGFA 1GKDA 1ZTQA 1CIZA 1EUBA 5B5OA 3OHLA 4WF6A 3I7IA 1GO8P 1EB6A 1ND1A
chains in the Genus database with same CATH superfamily
4ON1A 1BM6A 4HMAA 1KUHA 2O36A 1OMJA 3N2VA 1CAQA 1Y8JA 3LJGA 2AYKA 1JK3A 1UEAA 2RJPA 1FBLA 1XFUA 1R1JA 1SLMA 3U1RA 1CQRA 3HY7A 2JSDA 3EDHA 4H49A 3VTGA 3L0TA 3LJZA 4ILWD 1JAOA 5D1UA 4PKWA 1BKCI 1HY7A 3O64A 3LUMA 1BKCA 3KEJA 2DDYA 1G05A 3F19A 1IADA 1MNCA 1BKCE 1SLNA 3ZXHA 5LABA 3F15A 3LGPA 1G4KA 3O2XA 2Z2DA 4H2EA 1JANA 4H1QA 1USNA 4H3XA 4JA1A 1MMBA 1BZSA 4PKSA 1JIWP 1MMRA 2ERPA 1UMSA 1I73A 3EDZA 1PWPA 1QUAA 5I43A 3F18A 3WV3A 5I0LA 4XM8A 3LMCA 4G9LA 3TVCA 1A86A 1OO9A 1ROSA 2E2DA 1MMQA 1GE6A 3WV2A 2O3EA 1YOUA 4R3VA 3RTSA 1I76A 1OZ9A 1XM5A 1GO7P 3ELMA 3DSLA 5I2ZA 1BSWA 1HV5A 5I4OA 3MA2A 1UMTA 1O0QA 3USNA 4PKQA 4EFSA 3EDIA 1SU3A 1QJJA 4JP4A 3HBVP 4FXYP 2K2GA 3GBOA 4HX3A 5BOTA 3Q2HA 2MZEA 2USNA 2X3AA 4PKRA 1R1HA 1FM1A 4PKTA 3EWJA 2D1OA 3LUNA 1WNIA 1C8TA 1KUKA 4DD8A 2AIGP 3I7GA 2OW9A 4WKEA 2POJA 1CGEA 4G0DA 1BUVM 4XBHA 3EHYA 1AYKA 3HDAP 5BOYA 4H82A 5L79A 3EDGA 2V4BA 1S4BP 1YCMA 1QIAA 2ERQA 4QKZA 1D7XA 1AF0A 1HFCA 2X7MA 1BQOA 4DPEA 4JQGA 5D2BA 1A85A 2MZIA 3KHIA 3LE9A 1XUDA 4AIGA 5I12A 3TT4A 2W15A 3LKAA 3KRYA 1IABA 3HY9A 4DV8A 1AKLA 1QJIA 4IUWA 2YIGA 1CGLA 1JAPA 3F17A 1XFVA 2E3XA 1Y0VA 4WKIA 3LJTA 2CKIA 1ZP5A 3EHXA 1KUGA 1ATLA 4GR0A 1ASTA 3WV1A 3ZVSA 2X3BA 2J83A 3P1VA 2FV9A 1JH1A 1PWUA 4GWMA 2FV5A 5D1SA 3ZUKA 5H8XA 3DTEA 2MLSA 3LQ0A 1BQQM 3DPFA 4JPAA 2D1NA 1CK7A 3NX7A 3Q2GA 1JAQA 1SRPA 2OI0A 3LK8A 1XAXA 1YQYA 2KRJA 4FVLA 1CXVA 2YUFA 2SRTA 3LEAA 5L7FA 1I1IP 2N8RA 4WK7A 2JIHA 456CA 3AYKA 2JNPA 1O0TA 2W0DA 3B92A 2OXWA 2JT5A 1D5JA 1G9KA 4I03A 4Q1LA 3DTIA 1XFZA 1XFWA 1B3DA 4ZR5A 2L0RA 1Q3AA 4DF9A 2OW0A 3OHOA 1K7GA 3AYUA 966CA 1DMTA 1XURA 1Y93A 1B8YA 1K7QA 4WZVA 4XM6A 4GWNA 1BIWA 5CUHA 1K7IA 2W12A 2XS3A 4GF1A 1GE5A 3AIGA 4J4MA 2WO9A 1UTTA 2OY4A 1R54A 1JJ9A 4H76A 3DWBA 2W13A 3L0VA 4GR3A 1TVIA 4L6TA 3K7NA 3LIRA 1EAKA 3DNGA 1G49A 1C3IA 1KUFA 1HFSA 1PWWA 3TSKA 3HBUP 2W14A 3E8RA 2X3CA 2A8HA 2OXUA 4CTHA 1JIZA 3RTTA 2XS4A 3KEKA 1OM8A 2OW2A 1KBCA 1RMZA 1ZVXA 1SMPA 1KUIA 1JKYA 4A3WA 3DL1A 3G5CA 2OW1A 1IAAA 1XFYA 2Y6CA 3LIKA 2OVZA 1R55A 3KMEA 3N2UA 2K9CA 3KWVC 5BPAA 1ZXCA 2OVXA 2QPJA 1J7NA 1BUDA 1PWVA 1RM8A 3CKIA 4GUYA 1R1IA 3F16A 1IAGA 4XM7A 2OXZA 4H30A 1H71P 1OS9A 3HB2P 2CLTA 1IACA 1D8FA 4IN9A 2WOAA 1Z3JA 3LILA 2OY2A 2MZHA 5D1TA 2RJQA 1QICA 5B5PA 3DPEA 2YB9A 1SATA 1DTHA 2DW2A 3LQBA 4GQLA 4L7AA 4L19A 2HU6A 2WO8A 3VI1A 4XCTA 2DW1A 1L6JA 4I35A 1HTDA 4H84A 5CZMA 3BA0A 1OS2A 1XFXA 5D7WA 1UTZA 3P24A 4FXQA 3SHIA 4A7BA 2Y6DA 4L63A 1D8MA 1QIBA 3TS4A 5I3MA 2PJTA 830CA 4GR8A 1FLSA 5CXAA 4AUOA 1XUCA 2DDFA 3G42A 2JT6A 4AXQA 5JMYA 1IAEA 1ZXVA 3HYGA 2OZRA 1ZS0A 3F1AA 3HDBA 3B2ZA 1PWQA 1OM7A 3DTKA 3UVCA 1G12A 1OM6A 2MLRA 2J0TA 1MMPA 1GKCA 2EROA 1HOVA 2I47A 4AYKA 3V96B 2TCLA 2DW0A 1C7KA 1YP1A 4FU4A 3K7LA 3KECA 4JIJA 3KMCA 1GE7A 3B8ZA 5D3CA 4PKUA 1KAPP 4PKVA 4IJOA 1GXDA 1CGFA 1GKDA 1ZTQA 1CIZA 1EUBA 5B5OA 3OHLA 4WF6A 3I7IA 1GO8P 1EB6A 1ND1A
chains in the Genus database with same CATH topology
4ON1A 1BM6A 4HMAA 1KUHA 2O36A 1OMJA 3N2VA 1CAQA 1Y8JA 3LJGA 2AYKA 1JK3A 1UEAA 2RJPA 1FBLA 1XFUA 1R1JA 1SLMA 3U1RA 1CQRA 3HY7A 2JSDA 3EDHA 4H49A 3VTGA 3L0TA 3LJZA 4ILWD 1JAOA 5D1UA 4PKWA 1BKCI 1HY7A 3O64A 3LUMA 1BKCA 3KEJA 2DDYA 1G05A 3F19A 1IADA 1MNCA 1BKCE 1SLNA 3ZXHA 5LABA 3F15A 3LGPA 1G4KA 3O2XA 2Z2DA 4H2EA 1JANA 4H1QA 1USNA 4H3XA 4JA1A 1MMBA 1BZSA 4PKSA 1JIWP 1MMRA 2ERPA 1UMSA 1I73A 3EDZA 1PWPA 1QUAA 5I43A 3F18A 3WV3A 5I0LA 4XM8A 3LMCA 4G9LA 3TVCA 1A86A 1OO9A 1ROSA 2E2DA 1MMQA 1GE6A 3WV2A 2O3EA 1YOUA 4R3VA 3RTSA 1I76A 1GO7P 3ELMA 3DSLA 5I2ZA 1BSWA 1HV5A 5I4OA 3MA2A 1UMTA 1O0QA 3USNA 4PKQA 4EFSA 3EDIA 1SU3A 1QJJA 4JP4A 3HBVP 4FXYP 2K2GA 3GBOA 4HX3A 5BOTA 3Q2HA 2MZEA 2USNA 2X3AA 4PKRA 1R1HA 1FM1A 4PKTA 3EWJA 2D1OA 3LUNA 1WNIA 1C8TA 1KUKA 4DD8A 2AIGP 3I7GA 2OW9A 4WKEA 2POJA 1CGEA 4G0DA 1BUVM 4XBHA 3EHYA 1AYKA 3HDAP 5BOYA 4H82A 5L79A 3EDGA 2V4BA 1S4BP 1YCMA 1QIAA 2ERQA 4QKZA 1D7XA 1AF0A 1HFCA 2X7MA 1BQOA 4DPEA 4JQGA 5D2BA 1A85A 2MZIA 3KHIA 3LE9A 1XUDA 4AIGA 5I12A 3TT4A 2W15A 3LKAA 3KRYA 1IABA 3HY9A 4DV8A 1AKLA 1QJIA 4IUWA 2YIGA 1CGLA 1JAPA 3F17A 1XFVA 2E3XA 1Y0VA 4WKIA 3LJTA 2CKIA 1ZP5A 3EHXA 1KUGA 1ATLA 4GR0A 1ASTA 3WV1A 3ZVSA 2X3BA 2J83A 3P1VA 2FV9A 1JH1A 1PWUA 4GWMA 2FV5A 5D1SA 3ZUKA 5H8XA 3DTEA 2MLSA 3LQ0A 1BQQM 3DPFA 4JPAA 2D1NA 1CK7A 3NX7A 3Q2GA 1JAQA 1SRPA 2OI0A 3LK8A 1YQYA 2KRJA 4FVLA 1CXVA 2YUFA 2SRTA 3LEAA 5L7FA 1I1IP 2N8RA 4WK7A 2JIHA 456CA 3AYKA 2JNPA 1O0TA 2W0DA 3B92A 2OXWA 2JT5A 1D5JA 1G9KA 4I03A 4Q1LA 3DTIA 1XFZA 1XFWA 1B3DA 4ZR5A 2L0RA 1Q3AA 4DF9A 2OW0A 3OHOA 1K7GA 3AYUA 966CA 1DMTA 1XURA 1Y93A 1B8YA 1K7QA 4WZVA 4XM6A 4GWNA 1BIWA 5CUHA 1K7IA 2W12A 2XS3A 4GF1A 1GE5A 3AIGA 4J4MA 2WO9A 1UTTA 2OY4A 1R54A 1JJ9A 4H76A 3DWBA 2W13A 3L0VA 4GR3A 4L6TA 3K7NA 3LIRA 1EAKA 3DNGA 1G49A 1C3IA 1KUFA 1HFSA 1PWWA 3TSKA 3HBUP 2W14A 3E8RA 2X3CA 2A8HA 2OXUA 4CTHA 1JIZA 3RTTA 2XS4A 3KEKA 1OM8A 2OW2A 1KBCA 1RMZA 1ZVXA 1SMPA 1KUIA 1JKYA 4A3WA 3DL1A 3G5CA 2OW1A 1IAAA 1XFYA 2Y6CA 3LIKA 2OVZA 1R55A 3KMEA 3N2UA 2K9CA 3KWVC 5BPAA 1ZXCA 2OVXA 2QPJA 1J7NA 1BUDA 1PWVA 1RM8A 3CKIA 4GUYA 1R1IA 3F16A 1IAGA 4XM7A 2OXZA 4H30A 1H71P 1OS9A 3HB2P 2CLTA 1IACA 1D8FA 4IN9A 2WOAA 1Z3JA 3LILA 2OY2A 2MZHA 5D1TA 2RJQA 1QICA 5B5PA 3DPEA 2YB9A 1SATA 1DTHA 2DW2A 3LQBA 4GQLA 4L7AA 4L19A 2HU6A 2WO8A 3VI1A 4XCTA 2DW1A 1L6JA 4I35A 1HTDA 4H84A 5CZMA 3BA0A 1OS2A 1XFXA 5D7WA 1UTZA 3P24A 4FXQA 3SHIA 4A7BA 2Y6DA 4L63A 1D8MA 1QIBA 3TS4A 5I3MA 2PJTA 830CA 4GR8A 1FLSA 5CXAA 4AUOA 1XUCA 2DDFA 3G42A 2JT6A 4AXQA 5JMYA 1IAEA 1ZXVA 3HYGA 2OZRA 1ZS0A 3F1AA 3HDBA 3B2ZA 1PWQA 1OM7A 3DTKA 3UVCA 1G12A 1OM6A 2MLRA 2J0TA 1MMPA 1GKCA 2EROA 1HOVA 2I47A 4AYKA 3V96B 2TCLA 2DW0A 1C7KA 1YP1A 4FU4A 3K7LA 3KECA 4JIJA 3KMCA 1GE7A 3B8ZA 5D3CA 4PKUA 1KAPP 4PKVA 4IJOA 1GXDA 1CGFA 1GKDA 1ZTQA 1CIZA 1EUBA 5B5OA 3OHLA 4WF6A 3I7IA 1GO8P 1EB6A 1ND1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ON1 A;  1BM6 A;  4HMA A;  1KUH A;  2O36 A;  1OMJ A;  3N2V A;  1CAQ A;  1Y8J A;  3LJG A;  2AYK A;  1JK3 A;  1UEA A;  2RJP A;  1FBL A;  1XFU A;  1R1J A;  1SLM A;  3U1R A;  1CQR A;  3HY7 A;  2JSD A;  3EDH A;  4H49 A;  3VTG A;  3L0T A;  3LJZ A;  4ILW D;  1JAO A;  5D1U A;  4PKW A;  1BKC I;  1HY7 A;  3O64 A;  3LUM A;  1BKC A;  3KEJ A;  2DDY A;  1G05 A;  3F19 A;  1IAD A;  1MNC A;  1BKC E;  1SLN A;  3ZXH A;  5LAB A;  3F15 A;  3LGP A;  1G4K A;  3O2X A;  2Z2D A;  4H2E A;  1JAN A;  4H1Q A;  1USN A;  4H3X A;  4JA1 A;  1MMB A;  1BZS A;  4PKS A;  1JIW P;  1MMR A;  2ERP A;  1UMS A;  1I73 A;  3EDZ A;  1PWP A;  1QUA A;  5I43 A;  3F18 A;  3WV3 A;  5I0L A;  4XM8 A;  3LMC A;  4G9L A;  3TVC A;  1A86 A;  1OO9 A;  1ROS A;  2E2D A;  1MMQ A;  1GE6 A;  3WV2 A;  2O3E A;  1YOU A;  4R3V A;  3RTS A;  1I76 A;  1GO7 P;  3ELM A;  3DSL A;  5I2Z A;  1BSW A;  1HV5 A;  5I4O A;  3MA2 A;  1UMT A;  1O0Q A;  3USN A;  4PKQ A;  4EFS A;  3EDI A;  1SU3 A;  1QJJ A;  4JP4 A;  3HBV P;  4FXY P;  2K2G A;  3GBO A;  4HX3 A;  5BOT A;  3Q2H A;  2MZE A;  2USN A;  2X3A A;  4PKR A;  1R1H A;  1FM1 A;  4PKT A;  3EWJ A;  2D1O A;  3LUN A;  1WNI A;  1C8T A;  1KUK A;  4DD8 A;  2AIG P;  3I7G A;  2OW9 A;  4WKE A;  2POJ A;  1CGE A;  4G0D A;  1BUV M;  4XBH A;  3EHY A;  1AYK A;  3HDA P;  5BOY A;  4H82 A;  5L79 A;  3EDG A;  2V4B A;  1S4B P;  1YCM A;  1QIA A;  2ERQ A;  4QKZ A;  1D7X A;  1AF0 A;  1HFC A;  2X7M A;  1BQO A;  4DPE A;  4JQG A;  5D2B A;  1A85 A;  2MZI A;  3KHI A;  3LE9 A;  1XUD A;  4AIG A;  5I12 A;  3TT4 A;  2W15 A;  3LKA A;  3KRY A;  1IAB A;  3HY9 A;  4DV8 A;  1AKL A;  1QJI A;  4IUW A;  2YIG A;  1CGL A;  1JAP A;  3F17 A;  1XFV A;  2E3X A;  1Y0V A;  4WKI A;  3LJT A;  2CKI A;  1ZP5 A;  3EHX A;  1KUG A;  1ATL A;  4GR0 A;  1AST A;  3WV1 A;  3ZVS A;  2X3B A;  2J83 A;  3P1V A;  2FV9 A;  1JH1 A;  1PWU A;  4GWM A;  2FV5 A;  5D1S A;  3ZUK A;  5H8X A;  3LQ0 A;  2MLS A;  1BQQ M;  3DPF A;  4JPA A;  2D1N A;  1CK7 A;  3NX7 A;  3Q2G A;  1JAQ A;  1SRP A;  2OI0 A;  3LK8 A;  1YQY A;  2KRJ A;  4FVL A;  1CXV A;  2SRT A;  3LEA A;  5L7F A;  1I1I P;  2N8R A;  4WK7 A;  2JIH A;  456C A;  3AYK A;  2JNP A;  1O0T A;  2W0D A;  3B92 A;  2OXW A;  2JT5 A;  1D5J A;  1G9K A;  4I03 A;  4Q1L A;  1XFZ A;  1XFW A;  1B3D A;  4ZR5 A;  2L0R A;  1Q3A A;  4DF9 A;  2OW0 A;  3OHO A;  1K7G A;  3AYU A;  966C A;  1DMT A;  1XUR A;  1Y93 A;  1B8Y A;  1K7Q A;  4WZV A;  4XM6 A;  4GWN A;  1BIW A;  5CUH A;  1K7I A;  2W12 A;  2XS3 A;  4GF1 A;  1GE5 A;  3AIG A;  4J4M A;  2WO9 A;  1UTT A;  2OY4 A;  1R54 A;  1JJ9 A;  4H76 A;  3DWB A;  2W13 A;  3L0V A;  4GR3 A;  4L6T A;  3K7N A;  3LIR A;  1EAK A;  3DNG A;  1G49 A;  1C3I A;  1KUF A;  1HFS A;  1PWW A;  3TSK A;  3HBU P;  2W14 A;  3E8R A;  2X3C A;  2A8H A;  2OXU A;  4CTH A;  1JIZ A;  3RTT A;  2XS4 A;  3KEK A;  1OM8 A;  2OW2 A;  1KBC A;  1RMZ A;  1ZVX A;  1SMP A;  1KUI A;  1JKY A;  4A3W A;  3DL1 A;  3G5C A;  2OW1 A;  1IAA A;  1XFY A;  2Y6C A;  3LIK A;  2OVZ A;  1R55 A;  3KME A;  3N2U A;  2K9C A;  3KWV C;  5BPA A;  1ZXC A;  2OVX A;  2QPJ A;  1J7N A;  1BUD A;  1PWV A;  1RM8 A;  3CKI A;  4GUY A;  1R1I A;  3F16 A;  1IAG A;  4XM7 A;  2OXZ A;  4H30 A;  1H71 P;  1OS9 A;  3HB2 P;  2CLT A;  1IAC A;  1D8F A;  4IN9 A;  2WOA A;  1Z3J A;  3LIL A;  2OY2 A;  2MZH A;  5D1T A;  2RJQ A;  1QIC A;  5B5P A;  3DPE A;  2YB9 A;  1SAT A;  1DTH A;  2DW2 A;  3LQB A;  4GQL A;  4L19 A;  2HU6 A;  2WO8 A;  3VI1 A;  4XCT A;  2DW1 A;  1L6J A;  4I35 A;  1HTD A;  4H84 A;  5CZM A;  3BA0 A;  1OS2 A;  1XFX A;  5D7W A;  1UTZ A;  3P24 A;  4FXQ A;  3SHI A;  4A7B A;  2Y6D A;  4L63 A;  1D8M A;  1QIB A;  3TS4 A;  5I3M A;  2PJT A;  830C A;  4GR8 A;  1FLS A;  5CXA A;  4AUO A;  1XUC A;  2DDF A;  3G42 A;  2JT6 A;  4AXQ A;  5JMY A;  1IAE A;  1ZXV A;  3HYG A;  2OZR A;  1ZS0 A;  3F1A A;  3HDB A;  3B2Z A;  1PWQ A;  1OM7 A;  3UVC A;  1G12 A;  1OM6 A;  2MLR A;  2J0T A;  1MMP A;  1GKC A;  2ERO A;  1HOV A;  2I47 A;  4AYK A;  3V96 B;  2TCL A;  2DW0 A;  1C7K A;  1YP1 A;  4FU4 A;  3K7L A;  3KEC A;  4JIJ A;  3KMC A;  1GE7 A;  3B8Z A;  5D3C A;  4PKU A;  1KAP P;  4PKV A;  4IJO A;  1GXD A;  1CGF A;  1GKD A;  1ZTQ A;  1CIZ A;  1EUB A;  5B5O A;  3OHL A;  4WF6 A;  3I7I A;  1GO8 P;  1EB6 A;  1ND1 A; 
#chains in the Genus database with same CATH topology
 4ON1 A;  1BM6 A;  4HMA A;  1KUH A;  2O36 A;  1OMJ A;  3N2V A;  1CAQ A;  1Y8J A;  3LJG A;  2AYK A;  1JK3 A;  1UEA A;  2RJP A;  1FBL A;  1XFU A;  1R1J A;  1SLM A;  3U1R A;  1CQR A;  3HY7 A;  2JSD A;  3EDH A;  4H49 A;  3VTG A;  3L0T A;  3LJZ A;  4ILW D;  1JAO A;  5D1U A;  4PKW A;  1BKC I;  1HY7 A;  3O64 A;  3LUM A;  1BKC A;  3KEJ A;  2DDY A;  1G05 A;  3F19 A;  1IAD A;  1MNC A;  1BKC E;  1SLN A;  3ZXH A;  5LAB A;  3F15 A;  3LGP A;  1G4K A;  3O2X A;  2Z2D A;  4H2E A;  1JAN A;  4H1Q A;  1USN A;  4H3X A;  4JA1 A;  1MMB A;  1BZS A;  4PKS A;  1JIW P;  1MMR A;  2ERP A;  1UMS A;  1I73 A;  3EDZ A;  1PWP A;  1QUA A;  5I43 A;  3F18 A;  3WV3 A;  5I0L A;  4XM8 A;  3LMC A;  4G9L A;  3TVC A;  1A86 A;  1OO9 A;  1ROS A;  2E2D A;  1MMQ A;  1GE6 A;  3WV2 A;  2O3E A;  1YOU A;  4R3V A;  3RTS A;  1I76 A;  1OZ9 A;  1XM5 A;  1GO7 P;  3ELM A;  3DSL A;  5I2Z A;  1BSW A;  1HV5 A;  5I4O A;  3MA2 A;  1UMT A;  1O0Q A;  3USN A;  4PKQ A;  4EFS A;  3EDI A;  1SU3 A;  1QJJ A;  4JP4 A;  3HBV P;  4FXY P;  2K2G A;  3GBO A;  4HX3 A;  5BOT A;  3Q2H A;  2MZE A;  2USN A;  2X3A A;  4PKR A;  1R1H A;  1FM1 A;  4PKT A;  3EWJ A;  2D1O A;  3LUN A;  1WNI A;  1C8T A;  1KUK A;  4DD8 A;  2AIG P;  3I7G A;  2OW9 A;  4WKE A;  2POJ A;  1CGE A;  4G0D A;  1BUV M;  4XBH A;  3EHY A;  1AYK A;  3HDA P;  5BOY A;  4H82 A;  5L79 A;  3EDG A;  2V4B A;  1S4B P;  1YCM A;  1QIA A;  2ERQ A;  4QKZ A;  1D7X A;  1AF0 A;  1HFC A;  2X7M A;  1BQO A;  4DPE A;  4JQG A;  5D2B A;  1A85 A;  2MZI A;  3KHI A;  3LE9 A;  1XUD A;  4AIG A;  5I12 A;  3TT4 A;  2W15 A;  3LKA A;  3KRY A;  1IAB A;  3HY9 A;  4DV8 A;  1AKL A;  1QJI A;  4IUW A;  2YIG A;  1CGL A;  1JAP A;  3F17 A;  1XFV A;  2E3X A;  1Y0V A;  4WKI A;  3LJT A;  2CKI A;  1ZP5 A;  3EHX A;  1KUG A;  1ATL A;  4GR0 A;  1AST A;  3WV1 A;  3ZVS A;  2X3B A;  2J83 A;  3P1V A;  2FV9 A;  1JH1 A;  1PWU A;  4GWM A;  2FV5 A;  5D1S A;  3ZUK A;  5H8X A;  3DTE A;  2MLS A;  3LQ0 A;  1BQQ M;  3DPF A;  4JPA A;  2D1N A;  1CK7 A;  3NX7 A;  3Q2G A;  1JAQ A;  1SRP A;  2OI0 A;  3LK8 A;  1XAX A;  1YQY A;  2KRJ A;  4FVL A;  1CXV A;  2YUF A;  2SRT A;  3LEA A;  5L7F A;  1I1I P;  2N8R A;  4WK7 A;  2JIH A;  456C A;  3AYK A;  2JNP A;  1O0T A;  2W0D A;  3B92 A;  2OXW A;  2JT5 A;  1D5J A;  1G9K A;  4I03 A;  4Q1L A;  3DTI A;  1XFZ A;  1XFW A;  1B3D A;  4ZR5 A;  2L0R A;  1Q3A A;  4DF9 A;  2OW0 A;  3OHO A;  1K7G A;  3AYU A;  966C A;  1DMT A;  1XUR A;  1Y93 A;  1B8Y A;  1K7Q A;  4WZV A;  4XM6 A;  4GWN A;  1BIW A;  5CUH A;  1K7I A;  2W12 A;  2XS3 A;  4GF1 A;  1GE5 A;  3AIG A;  4J4M A;  2WO9 A;  1UTT A;  2OY4 A;  1R54 A;  1JJ9 A;  4H76 A;  3DWB A;  2W13 A;  3L0V A;  4GR3 A;  1TVI A;  4L6T A;  3K7N A;  3LIR A;  1EAK A;  3DNG A;  1G49 A;  1C3I A;  1KUF A;  1HFS A;  1PWW A;  3TSK A;  3HBU P;  2W14 A;  3E8R A;  2X3C A;  2A8H A;  2OXU A;  4CTH A;  1JIZ A;  3RTT A;  2XS4 A;  3KEK A;  1OM8 A;  2OW2 A;  1KBC A;  1RMZ A;  1ZVX A;  1SMP A;  1KUI A;  1JKY A;  4A3W A;  3DL1 A;  3G5C A;  2OW1 A;  1IAA A;  1XFY A;  2Y6C A;  3LIK A;  2OVZ A;  1R55 A;  3KME A;  3N2U A;  2K9C A;  3KWV C;  5BPA A;  1ZXC A;  2OVX A;  2QPJ A;  1J7N A;  1BUD A;  1PWV A;  1RM8 A;  3CKI A;  4GUY A;  1R1I A;  3F16 A;  1IAG A;  4XM7 A;  2OXZ A;  4H30 A;  1H71 P;  1OS9 A;  3HB2 P;  2CLT A;  1IAC A;  1D8F A;  4IN9 A;  2WOA A;  1Z3J A;  3LIL A;  2OY2 A;  2MZH A;  5D1T A;  2RJQ A;  1QIC A;  5B5P A;  3DPE A;  2YB9 A;  1SAT A;  1DTH A;  2DW2 A;  3LQB A;  4GQL A;  4L7A A;  4L19 A;  2HU6 A;  2WO8 A;  3VI1 A;  4XCT A;  2DW1 A;  1L6J A;  4I35 A;  1HTD A;  4H84 A;  5CZM A;  3BA0 A;  1OS2 A;  1XFX A;  5D7W A;  1UTZ A;  3P24 A;  4FXQ A;  3SHI A;  4A7B A;  2Y6D A;  4L63 A;  1D8M A;  1QIB A;  3TS4 A;  5I3M A;  2PJT A;  830C A;  4GR8 A;  1FLS A;  5CXA A;  4AUO A;  1XUC A;  2DDF A;  3G42 A;  2JT6 A;  4AXQ A;  5JMY A;  1IAE A;  1ZXV A;  3HYG A;  2OZR A;  1ZS0 A;  3F1A A;  3HDB A;  3B2Z A;  1PWQ A;  1OM7 A;  3DTK A;  3UVC A;  1G12 A;  1OM6 A;  2MLR A;  2J0T A;  1MMP A;  1GKC A;  2ERO A;  1HOV A;  2I47 A;  4AYK A;  3V96 B;  2TCL A;  2DW0 A;  1C7K A;  1YP1 A;  4FU4 A;  3K7L A;  3KEC A;  4JIJ A;  3KMC A;  1GE7 A;  3B8Z A;  5D3C A;  4PKU A;  1KAP P;  4PKV A;  4IJO A;  1GXD A;  1CGF A;  1GKD A;  1ZTQ A;  1CIZ A;  1EUB A;  5B5O A;  3OHL A;  4WF6 A;  3I7I A;  1GO8 P;  1EB6 A;  1ND1 A; 
#chains in the Genus database with same CATH homology
 4ON1 A;  1BM6 A;  4HMA A;  1KUH A;  2O36 A;  1OMJ A;  3N2V A;  1CAQ A;  1Y8J A;  3LJG A;  2AYK A;  1JK3 A;  1UEA A;  2RJP A;  1FBL A;  1XFU A;  1R1J A;  1SLM A;  3U1R A;  1CQR A;  3HY7 A;  2JSD A;  3EDH A;  4H49 A;  3VTG A;  3L0T A;  3LJZ A;  4ILW D;  1JAO A;  5D1U A;  4PKW A;  1BKC I;  1HY7 A;  3O64 A;  3LUM A;  1BKC A;  3KEJ A;  2DDY A;  1G05 A;  3F19 A;  1IAD A;  1MNC A;  1BKC E;  1SLN A;  3ZXH A;  5LAB A;  3F15 A;  3LGP A;  1G4K A;  3O2X A;  2Z2D A;  4H2E A;  1JAN A;  4H1Q A;  1USN A;  4H3X A;  4JA1 A;  1MMB A;  1BZS A;  4PKS A;  1JIW P;  1MMR A;  2ERP A;  1UMS A;  1I73 A;  3EDZ A;  1PWP A;  1QUA A;  5I43 A;  3F18 A;  3WV3 A;  5I0L A;  4XM8 A;  3LMC A;  4G9L A;  3TVC A;  1A86 A;  1OO9 A;  1ROS A;  2E2D A;  1MMQ A;  1GE6 A;  3WV2 A;  2O3E A;  1YOU A;  4R3V A;  3RTS A;  1I76 A;  1GO7 P;  3ELM A;  3DSL A;  5I2Z A;  1BSW A;  1HV5 A;  5I4O A;  3MA2 A;  1UMT A;  1O0Q A;  3USN A;  4PKQ A;  4EFS A;  3EDI A;  1SU3 A;  1QJJ A;  4JP4 A;  3HBV P;  4FXY P;  2K2G A;  3GBO A;  4HX3 A;  5BOT A;  3Q2H A;  2MZE A;  2USN A;  2X3A A;  4PKR A;  1R1H A;  1FM1 A;  4PKT A;  3EWJ A;  2D1O A;  3LUN A;  1WNI A;  1C8T A;  1KUK A;  4DD8 A;  2AIG P;  3I7G A;  2OW9 A;  4WKE A;  2POJ A;  1CGE A;  4G0D A;  1BUV M;  4XBH A;  3EHY A;  1AYK A;  3HDA P;  5BOY A;  4H82 A;  5L79 A;  3EDG A;  2V4B A;  1S4B P;  1YCM A;  1QIA A;  2ERQ A;  4QKZ A;  1D7X A;  1AF0 A;  1HFC A;  2X7M A;  1BQO A;  4DPE A;  4JQG A;  5D2B A;  1A85 A;  2MZI A;  3KHI A;  3LE9 A;  1XUD A;  4AIG A;  5I12 A;  3TT4 A;  2W15 A;  3LKA A;  3KRY A;  1IAB A;  3HY9 A;  4DV8 A;  1AKL A;  1QJI A;  4IUW A;  2YIG A;  1CGL A;  1JAP A;  3F17 A;  1XFV A;  2E3X A;  1Y0V A;  4WKI A;  3LJT A;  2CKI A;  1ZP5 A;  3EHX A;  1KUG A;  1ATL A;  4GR0 A;  1AST A;  3WV1 A;  3ZVS A;  2X3B A;  2J83 A;  3P1V A;  2FV9 A;  1JH1 A;  1PWU A;  4GWM A;  2FV5 A;  5D1S A;  3ZUK A;  5H8X A;  3DTE A;  2MLS A;  3LQ0 A;  1BQQ M;  3DPF A;  4JPA A;  2D1N A;  1CK7 A;  3NX7 A;  3Q2G A;  1JAQ A;  1SRP A;  2OI0 A;  3LK8 A;  1YQY A;  2KRJ A;  4FVL A;  1CXV A;  2YUF A;  2SRT A;  3LEA A;  5L7F A;  1I1I P;  2N8R A;  4WK7 A;  2JIH A;  456C A;  3AYK A;  2JNP A;  1O0T A;  2W0D A;  3B92 A;  2OXW A;  2JT5 A;  1D5J A;  1G9K A;  4I03 A;  4Q1L A;  3DTI A;  1XFZ A;  1XFW A;  1B3D A;  4ZR5 A;  2L0R A;  1Q3A A;  4DF9 A;  2OW0 A;  3OHO A;  1K7G A;  3AYU A;  966C A;  1DMT A;  1XUR A;  1Y93 A;  1B8Y A;  1K7Q A;  4WZV A;  4XM6 A;  4GWN A;  1BIW A;  5CUH A;  1K7I A;  2W12 A;  2XS3 A;  4GF1 A;  1GE5 A;  3AIG A;  4J4M A;  2WO9 A;  1UTT A;  2OY4 A;  1R54 A;  1JJ9 A;  4H76 A;  3DWB A;  2W13 A;  3L0V A;  4GR3 A;  4L6T A;  3K7N A;  3LIR A;  1EAK A;  3DNG A;  1G49 A;  1C3I A;  1KUF A;  1HFS A;  1PWW A;  3TSK A;  3HBU P;  2W14 A;  3E8R A;  2X3C A;  2A8H A;  2OXU A;  4CTH A;  1JIZ A;  3RTT A;  2XS4 A;  3KEK A;  1OM8 A;  2OW2 A;  1KBC A;  1RMZ A;  1ZVX A;  1SMP A;  1KUI A;  1JKY A;  4A3W A;  3DL1 A;  3G5C A;  2OW1 A;  1IAA A;  1XFY A;  2Y6C A;  3LIK A;  2OVZ A;  1R55 A;  3KME A;  3N2U A;  2K9C A;  3KWV C;  5BPA A;  1ZXC A;  2OVX A;  2QPJ A;  1J7N A;  1BUD A;  1PWV A;  1RM8 A;  3CKI A;  4GUY A;  1R1I A;  3F16 A;  1IAG A;  4XM7 A;  2OXZ A;  4H30 A;  1H71 P;  1OS9 A;  3HB2 P;  2CLT A;  1IAC A;  1D8F A;  4IN9 A;  2WOA A;  1Z3J A;  3LIL A;  2OY2 A;  2MZH A;  5D1T A;  2RJQ A;  1QIC A;  5B5P A;  3DPE A;  2YB9 A;  1SAT A;  1DTH A;  2DW2 A;  3LQB A;  4GQL A;  4L7A A;  4L19 A;  2HU6 A;  2WO8 A;  3VI1 A;  4XCT A;  2DW1 A;  1L6J A;  4I35 A;  1HTD A;  4H84 A;  5CZM A;  3BA0 A;  1OS2 A;  1XFX A;  5D7W A;  1UTZ A;  3P24 A;  4FXQ A;  3SHI A;  4A7B A;  2Y6D A;  4L63 A;  1D8M A;  1QIB A;  3TS4 A;  5I3M A;  2PJT A;  830C A;  4GR8 A;  1FLS A;  5CXA A;  4AUO A;  1XUC A;  2DDF A;  3G42 A;  2JT6 A;  4AXQ A;  5JMY A;  1IAE A;  1ZXV A;  3HYG A;  2OZR A;  1ZS0 A;  3F1A A;  3HDB A;  3B2Z A;  1PWQ A;  1OM7 A;  3DTK A;  3UVC A;  1G12 A;  1OM6 A;  2MLR A;  2J0T A;  1MMP A;  1GKC A;  2ERO A;  1HOV A;  2I47 A;  4AYK A;  3V96 B;  2TCL A;  2DW0 A;  1C7K A;  1YP1 A;  4FU4 A;  3K7L A;  3KEC A;  4JIJ A;  3KMC A;  1GE7 A;  3B8Z A;  5D3C A;  4PKU A;  1KAP P;  4PKV A;  4IJO A;  1GXD A;  1CGF A;  1GKD A;  1ZTQ A;  1CIZ A;  1EUB A;  5B5O A;  3OHL A;  4WF6 A;  3I7I A;  1GO8 P;  1EB6 A;  1ND1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...