2Y6CA

The discovery of mmp7 inhibitors exploiting a novel selectivity trigger
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
165
structure length
161
Chain Sequence
GYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYPQNFKLSQDDIKGIQKLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Discovery of Mmp7 Inhibitors Exploiting a Novel Selectivity Trigger.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords MATRILYSIN
total genus 48
structure length 161
sequence length 165
ec nomenclature ec 3.4.24.23: Matrilysin.
pdb deposition date 2011-01-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2y6cA00
3EHYA 1L6JA 1SRPA 3LJTA 3KMEA 3P1VA 1CQRA 1SU3A 3TVCA 4FXQA 3HB2P 1DMTA 2USNA 3AYKA 1BIWA 2QPJA 3HYGA 4R3VA 1BSWA 1H71P 1RM8A 3LUNA 4XBHA 1FLSA 2ERPA 5CXAA 1K7QA 3G42A 3LJZA 1YCMA 3V96B 3LILA 3Q2GA 1R54A 2X7MA 2W12A 5I0LA 1XURA 2DDYA 1I1IP 1ASTA 1PWPA 3WV2A 1EAKA 1Y93A 3HDBA 3EDHA 2DW0A 1BM6A 1ZS0A 2OZRA 4FXYP 1EUBA 3LMCA 1OS9A 3F19A 3LIRA 4L6TA 2OXUA 1ZXCA 3F15A 4FVLA 4J4MA 2K2GA 3DPFA 1B3DA 3CKIA 3LIKA 3EDGA 5BOTA 3UVCA 2J83A 4FU4A 2AYKA 4L63A 1HV5A 1JJ9A 1YQYA 2JT5A 2OW2A 2OVZA 3KEKA 3HBVP 5LABA 2OW1A 1ATLA 1FM1A 1QJJA 4AXQA 2E3XA 1AYKA 3DWBA 4ZR5A 3RTSA 4H84A 5CZMA 2JIHA 2X3BA 1GE7A 3L0TA 1UTZA 1D5JA 1GO8P 1HY7A 1PWVA 3EWJA 3U1RA 5I12A 2EROA 1O0QA 2TCLA 3DPEA 3HBUP 3NX7A 4JA1A 4WF6A 4GR0A 3BA0A 1XFWA 2OVXA 3F17A 3ZVSA 3LKAA 1BZSA 5B5PA 1JKYA 2OW9A 4WZVA 3DNGA 3AYUA 4G9LA 4PKQA 3WV3A 1JIZA 3RTTA 3I7IA 4A7BA 4JP4A 1MMRA 5L79A 4PKSA 2KRJA 4PKVA 4AUOA 2W0DA 2CLTA 1UMTA 3K7LA 2JSDA 4GR8A 2PJTA 3USNA 2E2DA 3N2VA 5B5OA 1MMPA 4H2EA 4PKTA 5I3MA 1C8TA 1Y0VA 2WOAA 2JNPA 3EDZA 5JMYA 3EDIA 1R1HA 1HOVA 1BUVM 1QUAA 4XCTA 3B8ZA 2I47A 1A85A 5D1SA 966CA 1D8MA 2D1NA 2WO8A 1ND1A 3EHXA 1SATA 3WV1A 2RJPA 4CTHA 1I76A 3I7GA 2JT6A 2OY2A 4AYKA 1GKCA 3LUMA 4H76A 1ZP5A 4G0DA 5D1UA 3KWVC 4L19A 3TT4A 3ELMA 4IJOA 1IAEA 4H1QA 2K9CA 3F16A 1G4KA 2O3EA 1HFSA 1ZXVA 4H49A 1ZTQA 1ZVXA 1JANA 4DD8A 1OS2A 1BQOA 1FBLA 2OXZA 3OHLA 2V4BA 2W14A 4IN9A 1DTHA 1CK7A 1MMBA 1KAPP 4GUYA 1AF0A 1AKLA 3HY9A 3SHIA 3TS4A 1RMZA 1IAGA 1BKCI 1EB6A 3HDAP 2DDFA 3O64A 3LE9A 1BKCA 1A86A 1I73A 1YOUA 4QKZA 4PKUA 1IADA 1QJIA 2CKIA 4HMAA 4Q1LA 1SLMA 1CIZA 4JIJA 3KEJA 1R55A 1MNCA 2N8RA 5D1TA 3DSLA 4WKIA 4ILWD 2AIGP 5I43A 3KRYA 1KUGA 2YIGA 1XFZA 4PKRA 4WK7A 2W15A 2WO9A 3VTGA 2OXWA 3LQBA 4H30A 1KUHA 1OO9A 2MZIA 1MMQA 4XM6A 4XM8A 2O36A 1KUFA 1G05A 3LGPA 5BPAA 3HY7A 1Z3JA 2Y6CA 1S4BP 4I35A 1QICA 4WKEA 3B92A 3B2ZA 830CA 2Z2DA 2SRTA 3P24A 3F1AA 3L0VA 1GE6A 2FV9A 1Q3AA 1BKCE 2X3CA 1CXVA 1JAOA 5I2ZA 1CGFA 1IABA 1XFYA 4ON1A 5D2BA 3KHIA 1GE5A 4H3XA 4GF1A 1IAAA 1G9KA 3ZXHA 1O0TA 1R1JA 1SMPA 3Q2HA 3ZUKA 2MLSA 1JH1A 1OM7A 2J0TA 1YP1A 1WNIA 1OM6A 1CGLA 1K7GA 4DF9A 1BQQM 1BUDA 1PWUA 3K7NA 1XUDA 2MZEA 1USNA 5D3CA 1GO7P 5L7FA 1G12A 2OY4A 3F18A 2X3AA 4AIGA 2HU6A 4A3WA 2POJA 2OW0A 1JIWP 2A8HA 3O2XA 3AIGA 2OI0A 1B8YA 4GWMA 1CGEA 1G49A 1OM8A 1OMJA 1K7IA 1IACA 5CUHA 1C3IA 4JPAA 3LQ0A 1UMSA 3KMCA 4H82A 5D7WA 1C7KA 2D1OA 1XFVA 1UEAA 2Y6DA 1UTTA 1XFUA 4GWNA 1XFXA 2MZHA 1CAQA 4HX3A 2DW2A 1QIAA 2YB9A 1D7XA 2DW1A 456CA 4JQGA 1XUCA 1JK3A 4EFSA 1JAQA 1KUIA 2L0RA 3LJGA 3DL1A 1R1IA 2XS4A 1GKDA 2RJQA 3LEAA 5H8XA 4XM7A 1D8FA 2FV5A 1JAPA 3E8RA 1HTDA 1HFCA 3VI1A 4IUWA 1PWQA 5I4OA 4DV8A 3GBOA 1GXDA 1KBCA 4DPEA 1KUKA 1PWWA 3KECA 3MA2A 2XS3A 3OHOA 3N2UA 1Y8JA 4GR3A 1ROSA 3G5CA 2W13A 3LK8A 2ERQA 3TSKA 4GQLA 4PKWA 1SLNA 1QIBA 5BOYA 2MLRA 1J7NA 4I03A
chains in the Genus database with same CATH superfamily
3EHYA 1L6JA 1SRPA 3LJTA 3KMEA 3P1VA 1CQRA 1SU3A 3TVCA 4FXQA 3HB2P 1DMTA 2USNA 3AYKA 1BIWA 2QPJA 3HYGA 4R3VA 1BSWA 1H71P 1RM8A 3LUNA 4XBHA 1FLSA 2ERPA 5CXAA 1K7QA 3G42A 4L7AA 3LJZA 1YCMA 3V96B 3LILA 3Q2GA 1R54A 2X7MA 2W12A 5I0LA 1XURA 2DDYA 3DTIA 1I1IP 1ASTA 1PWPA 3WV2A 1EAKA 1Y93A 3HDBA 3EDHA 2DW0A 1BM6A 1ZS0A 2OZRA 4FXYP 1EUBA 3LMCA 1OS9A 3F19A 3DTEA 3LIRA 4L6TA 2OXUA 1ZXCA 3F15A 4FVLA 4J4MA 2K2GA 3DPFA 1B3DA 3CKIA 3LIKA 3EDGA 5BOTA 3UVCA 2J83A 4FU4A 2AYKA 4L63A 1HV5A 1JJ9A 1YQYA 2JT5A 2OW2A 2OVZA 3KEKA 3HBVP 3DTKA 5LABA 2OW1A 1OZ9A 1ATLA 1FM1A 1QJJA 4AXQA 2E3XA 1AYKA 3DWBA 4ZR5A 3RTSA 4H84A 5CZMA 2JIHA 2X3BA 1GE7A 3L0TA 1UTZA 1D5JA 1GO8P 1HY7A 1PWVA 3EWJA 3U1RA 5I12A 2EROA 1O0QA 2TCLA 3DPEA 3HBUP 3NX7A 4JA1A 4WF6A 4GR0A 3BA0A 1XFWA 2OVXA 3F17A 3ZVSA 3LKAA 1BZSA 5B5PA 1JKYA 2OW9A 4WZVA 3DNGA 3AYUA 4G9LA 4PKQA 3WV3A 1JIZA 3RTTA 3I7IA 4A7BA 4JP4A 1MMRA 5L79A 4PKSA 2KRJA 4PKVA 4AUOA 2W0DA 2CLTA 1UMTA 3K7LA 2JSDA 4GR8A 2PJTA 3USNA 2E2DA 3N2VA 5B5OA 1MMPA 4H2EA 4PKTA 5I3MA 1C8TA 1Y0VA 2WOAA 2JNPA 3EDZA 5JMYA 3EDIA 1R1HA 1HOVA 1BUVM 1QUAA 4XCTA 3B8ZA 2I47A 1A85A 5D1SA 966CA 1D8MA 2D1NA 2WO8A 1ND1A 3EHXA 1SATA 3WV1A 2RJPA 4CTHA 1I76A 3I7GA 2JT6A 2OY2A 4AYKA 1GKCA 3LUMA 4H76A 1ZP5A 4G0DA 5D1UA 3KWVC 4L19A 3TT4A 3ELMA 4IJOA 1IAEA 4H1QA 2K9CA 3F16A 1G4KA 2O3EA 1HFSA 1ZXVA 4H49A 1ZTQA 1ZVXA 1JANA 4DD8A 1OS2A 1BQOA 1FBLA 2OXZA 3OHLA 2V4BA 2W14A 4IN9A 1DTHA 1CK7A 1MMBA 1KAPP 4GUYA 1AF0A 1AKLA 3HY9A 3SHIA 3TS4A 1RMZA 1IAGA 1BKCI 1EB6A 3HDAP 2DDFA 3O64A 3LE9A 1BKCA 1A86A 1I73A 1YOUA 4QKZA 4PKUA 2YUFA 1IADA 1QJIA 1TVIA 2CKIA 4HMAA 4Q1LA 1SLMA 1CIZA 4JIJA 3KEJA 1R55A 1MNCA 2N8RA 5D1TA 3DSLA 4WKIA 4ILWD 2AIGP 5I43A 3KRYA 1KUGA 2YIGA 1XFZA 4PKRA 4WK7A 2W15A 2WO9A 3VTGA 2OXWA 3LQBA 4H30A 1KUHA 1OO9A 2MZIA 1MMQA 4XM6A 4XM8A 2O36A 1KUFA 1G05A 3LGPA 5BPAA 3HY7A 1Z3JA 2Y6CA 1S4BP 4I35A 1QICA 4WKEA 3B92A 3B2ZA 830CA 2Z2DA 2SRTA 3P24A 3F1AA 3L0VA 1GE6A 2FV9A 1Q3AA 1BKCE 2X3CA 1CXVA 1JAOA 5I2ZA 1CGFA 1IABA 1XFYA 4ON1A 5D2BA 3KHIA 1GE5A 4H3XA 4GF1A 1IAAA 1G9KA 3ZXHA 1O0TA 1R1JA 1SMPA 3Q2HA 3ZUKA 2MLSA 1JH1A 1OM7A 2J0TA 1YP1A 1WNIA 1OM6A 1CGLA 1XM5A 1K7GA 4DF9A 1BQQM 1BUDA 1PWUA 3K7NA 1XUDA 2MZEA 1USNA 5D3CA 1GO7P 5L7FA 1G12A 2OY4A 3F18A 2X3AA 4AIGA 2HU6A 4A3WA 2POJA 1XAXA 2OW0A 1JIWP 2A8HA 3O2XA 3AIGA 2OI0A 1B8YA 4GWMA 1CGEA 1G49A 1OM8A 1OMJA 1K7IA 1IACA 5CUHA 1C3IA 4JPAA 3LQ0A 1UMSA 3KMCA 4H82A 5D7WA 1C7KA 2D1OA 1XFVA 1UEAA 2Y6DA 1UTTA 1XFUA 4GWNA 1XFXA 2MZHA 1CAQA 4HX3A 2DW2A 1QIAA 2YB9A 1D7XA 2DW1A 456CA 4JQGA 1XUCA 1JK3A 4EFSA 1JAQA 1KUIA 2L0RA 3LJGA 3DL1A 1R1IA 2XS4A 1GKDA 2RJQA 3LEAA 5H8XA 4XM7A 1D8FA 2FV5A 1JAPA 3E8RA 1HTDA 1HFCA 3VI1A 4IUWA 1PWQA 5I4OA 4DV8A 3GBOA 1GXDA 1KBCA 4DPEA 1KUKA 1PWWA 3KECA 3MA2A 2XS3A 3OHOA 3N2UA 1Y8JA 4GR3A 1ROSA 3G5CA 2W13A 3LK8A 2ERQA 3TSKA 4GQLA 4PKWA 1SLNA 1QIBA 5BOYA 2MLRA 1J7NA 4I03A
chains in the Genus database with same CATH topology
3EHYA 1L6JA 1SRPA 3LJTA 3KMEA 3P1VA 1CQRA 1SU3A 3TVCA 4FXQA 3HB2P 1DMTA 2USNA 3AYKA 1BIWA 2QPJA 3HYGA 4R3VA 1BSWA 1H71P 1RM8A 3LUNA 4XBHA 1FLSA 2ERPA 5CXAA 1K7QA 3G42A 4L7AA 3LJZA 1YCMA 3V96B 3LILA 3Q2GA 1R54A 2X7MA 2W12A 5I0LA 1XURA 2DDYA 3DTIA 1I1IP 1ASTA 1PWPA 3WV2A 1EAKA 1Y93A 3HDBA 3EDHA 2DW0A 1BM6A 1ZS0A 2OZRA 4FXYP 1EUBA 3LMCA 1OS9A 3F19A 3DTEA 3LIRA 4L6TA 2OXUA 1ZXCA 3F15A 4FVLA 4J4MA 2K2GA 3DPFA 1B3DA 3CKIA 3LIKA 3EDGA 5BOTA 3UVCA 2J83A 4FU4A 2AYKA 4L63A 1HV5A 1JJ9A 1YQYA 2JT5A 2OW2A 2OVZA 3KEKA 3HBVP 3DTKA 5LABA 2OW1A 1ATLA 1FM1A 1QJJA 4AXQA 2E3XA 1AYKA 3DWBA 4ZR5A 3RTSA 4H84A 5CZMA 2JIHA 2X3BA 1GE7A 3L0TA 1UTZA 1D5JA 1GO8P 1HY7A 1PWVA 3EWJA 3U1RA 5I12A 2EROA 1O0QA 2TCLA 3DPEA 3HBUP 3NX7A 4JA1A 4WF6A 4GR0A 3BA0A 1XFWA 2OVXA 3F17A 3ZVSA 3LKAA 1BZSA 5B5PA 1JKYA 2OW9A 4WZVA 3DNGA 3AYUA 4G9LA 4PKQA 3WV3A 1JIZA 3RTTA 3I7IA 4A7BA 4JP4A 1MMRA 5L79A 4PKSA 2KRJA 4PKVA 4AUOA 2W0DA 2CLTA 1UMTA 3K7LA 2JSDA 4GR8A 2PJTA 3USNA 2E2DA 3N2VA 5B5OA 1MMPA 4H2EA 4PKTA 5I3MA 1C8TA 1Y0VA 2WOAA 2JNPA 3EDZA 5JMYA 3EDIA 1R1HA 1HOVA 1BUVM 1QUAA 4XCTA 3B8ZA 2I47A 1A85A 5D1SA 966CA 1D8MA 2D1NA 2WO8A 1ND1A 3EHXA 1SATA 3WV1A 2RJPA 4CTHA 1I76A 3I7GA 2JT6A 2OY2A 4AYKA 1GKCA 3LUMA 4H76A 1ZP5A 4G0DA 5D1UA 3KWVC 4L19A 3TT4A 3ELMA 4IJOA 1IAEA 4H1QA 2K9CA 3F16A 1G4KA 2O3EA 1HFSA 1ZXVA 4H49A 1ZTQA 1ZVXA 1JANA 4DD8A 1OS2A 1BQOA 1FBLA 2OXZA 3OHLA 2V4BA 2W14A 4IN9A 1DTHA 1CK7A 1MMBA 1KAPP 4GUYA 1AF0A 1AKLA 3HY9A 3SHIA 3TS4A 1RMZA 1IAGA 1BKCI 1EB6A 3HDAP 2DDFA 3O64A 3LE9A 1BKCA 1A86A 1I73A 1YOUA 4QKZA 4PKUA 2YUFA 1IADA 1QJIA 2CKIA 4HMAA 4Q1LA 1SLMA 1CIZA 4JIJA 3KEJA 1R55A 1MNCA 2N8RA 5D1TA 3DSLA 4WKIA 4ILWD 2AIGP 5I43A 3KRYA 1KUGA 2YIGA 1XFZA 4PKRA 4WK7A 2W15A 2WO9A 3VTGA 2OXWA 3LQBA 4H30A 1KUHA 1OO9A 2MZIA 1MMQA 4XM6A 4XM8A 2O36A 1KUFA 1G05A 3LGPA 5BPAA 3HY7A 1Z3JA 2Y6CA 1S4BP 4I35A 1QICA 4WKEA 3B92A 3B2ZA 830CA 2Z2DA 2SRTA 3P24A 3F1AA 3L0VA 1GE6A 2FV9A 1Q3AA 1BKCE 2X3CA 1CXVA 1JAOA 5I2ZA 1CGFA 1IABA 1XFYA 4ON1A 5D2BA 3KHIA 1GE5A 4H3XA 4GF1A 1IAAA 1G9KA 3ZXHA 1O0TA 1R1JA 1SMPA 3Q2HA 3ZUKA 2MLSA 1JH1A 1OM7A 2J0TA 1YP1A 1WNIA 1OM6A 1CGLA 1K7GA 4DF9A 1BQQM 1BUDA 1PWUA 3K7NA 1XUDA 2MZEA 1USNA 5D3CA 1GO7P 5L7FA 1G12A 2OY4A 3F18A 2X3AA 4AIGA 2HU6A 4A3WA 2POJA 2OW0A 1JIWP 2A8HA 3O2XA 3AIGA 2OI0A 1B8YA 4GWMA 1CGEA 1G49A 1OM8A 1OMJA 1K7IA 1IACA 5CUHA 1C3IA 4JPAA 3LQ0A 1UMSA 3KMCA 4H82A 5D7WA 1C7KA 2D1OA 1XFVA 1UEAA 2Y6DA 1UTTA 1XFUA 4GWNA 1XFXA 2MZHA 1CAQA 4HX3A 2DW2A 1QIAA 2YB9A 1D7XA 2DW1A 456CA 4JQGA 1XUCA 1JK3A 4EFSA 1JAQA 1KUIA 2L0RA 3LJGA 3DL1A 1R1IA 2XS4A 1GKDA 2RJQA 3LEAA 5H8XA 4XM7A 1D8FA 2FV5A 1JAPA 3E8RA 1HTDA 1HFCA 3VI1A 4IUWA 1PWQA 5I4OA 4DV8A 3GBOA 1GXDA 1KBCA 4DPEA 1KUKA 1PWWA 3KECA 3MA2A 2XS3A 3OHOA 3N2UA 1Y8JA 4GR3A 1ROSA 3G5CA 2W13A 3LK8A 2ERQA 3TSKA 4GQLA 4PKWA 1SLNA 1QIBA 5BOYA 2MLRA 1J7NA 4I03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EHY A;  1L6J A;  1SRP A;  3LJT A;  3KME A;  3P1V A;  1CQR A;  1SU3 A;  3TVC A;  4FXQ A;  3HB2 P;  1DMT A;  2USN A;  3AYK A;  1BIW A;  2QPJ A;  3HYG A;  4R3V A;  1BSW A;  1H71 P;  1RM8 A;  3LUN A;  4XBH A;  1FLS A;  2ERP A;  5CXA A;  1K7Q A;  3G42 A;  3LJZ A;  1YCM A;  3V96 B;  3LIL A;  3Q2G A;  1R54 A;  2X7M A;  2W12 A;  5I0L A;  1XUR A;  2DDY A;  1I1I P;  1AST A;  1PWP A;  3WV2 A;  1EAK A;  1Y93 A;  3HDB A;  3EDH A;  2DW0 A;  1BM6 A;  1ZS0 A;  2OZR A;  4FXY P;  1EUB A;  3LMC A;  1OS9 A;  3F19 A;  3LIR A;  4L6T A;  2OXU A;  1ZXC A;  3F15 A;  4FVL A;  4J4M A;  2K2G A;  3DPF A;  1B3D A;  3CKI A;  3LIK A;  3EDG A;  5BOT A;  3UVC A;  2J83 A;  4FU4 A;  2AYK A;  4L63 A;  1HV5 A;  1JJ9 A;  1YQY A;  2JT5 A;  2OW2 A;  2OVZ A;  3KEK A;  3HBV P;  5LAB A;  2OW1 A;  1ATL A;  1FM1 A;  1QJJ A;  4AXQ A;  2E3X A;  1AYK A;  3DWB A;  4ZR5 A;  3RTS A;  4H84 A;  5CZM A;  2JIH A;  2X3B A;  1GE7 A;  3L0T A;  1UTZ A;  1D5J A;  1GO8 P;  1HY7 A;  1PWV A;  3EWJ A;  3U1R A;  5I12 A;  2ERO A;  1O0Q A;  2TCL A;  3DPE A;  3HBU P;  3NX7 A;  4JA1 A;  4WF6 A;  4GR0 A;  3BA0 A;  1XFW A;  2OVX A;  3F17 A;  3ZVS A;  3LKA A;  1BZS A;  5B5P A;  1JKY A;  2OW9 A;  4WZV A;  3DNG A;  3AYU A;  4G9L A;  4PKQ A;  3WV3 A;  1JIZ A;  3RTT A;  3I7I A;  4A7B A;  4JP4 A;  1MMR A;  5L79 A;  4PKS A;  2KRJ A;  4PKV A;  4AUO A;  2W0D A;  2CLT A;  1UMT A;  3K7L A;  2JSD A;  4GR8 A;  2PJT A;  3USN A;  2E2D A;  3N2V A;  5B5O A;  1MMP A;  4H2E A;  4PKT A;  5I3M A;  1C8T A;  1Y0V A;  2WOA A;  2JNP A;  3EDZ A;  5JMY A;  3EDI A;  1R1H A;  1HOV A;  1BUV M;  1QUA A;  4XCT A;  3B8Z A;  2I47 A;  1A85 A;  5D1S A;  966C A;  1D8M A;  2D1N A;  2WO8 A;  1ND1 A;  3EHX A;  1SAT A;  3WV1 A;  2RJP A;  4CTH A;  1I76 A;  3I7G A;  2JT6 A;  2OY2 A;  4AYK A;  1GKC A;  3LUM A;  4H76 A;  1ZP5 A;  4G0D A;  5D1U A;  3KWV C;  4L19 A;  3TT4 A;  3ELM A;  4IJO A;  1IAE A;  4H1Q A;  2K9C A;  3F16 A;  1G4K A;  2O3E A;  1HFS A;  1ZXV A;  4H49 A;  1ZTQ A;  1ZVX A;  1JAN A;  4DD8 A;  1OS2 A;  1BQO A;  1FBL A;  2OXZ A;  3OHL A;  2V4B A;  2W14 A;  4IN9 A;  1DTH A;  1CK7 A;  1MMB A;  1KAP P;  4GUY A;  1AF0 A;  1AKL A;  3HY9 A;  3SHI A;  3TS4 A;  1RMZ A;  1IAG A;  1BKC I;  1EB6 A;  3HDA P;  2DDF A;  3O64 A;  3LE9 A;  1BKC A;  1A86 A;  1I73 A;  1YOU A;  4QKZ A;  4PKU A;  1IAD A;  1QJI A;  2CKI A;  4HMA A;  4Q1L A;  1SLM A;  1CIZ A;  4JIJ A;  3KEJ A;  1R55 A;  1MNC A;  2N8R A;  5D1T A;  3DSL A;  4WKI A;  4ILW D;  2AIG P;  5I43 A;  3KRY A;  1KUG A;  2YIG A;  1XFZ A;  4PKR A;  4WK7 A;  2W15 A;  2WO9 A;  3VTG A;  2OXW A;  3LQB A;  4H30 A;  1KUH A;  1OO9 A;  2MZI A;  1MMQ A;  4XM6 A;  4XM8 A;  2O36 A;  1KUF A;  1G05 A;  3LGP A;  5BPA A;  3HY7 A;  1Z3J A;  2Y6C A;  1S4B P;  4I35 A;  1QIC A;  4WKE A;  3B92 A;  3B2Z A;  830C A;  2Z2D A;  2SRT A;  3P24 A;  3F1A A;  3L0V A;  1GE6 A;  2FV9 A;  1Q3A A;  1BKC E;  2X3C A;  1CXV A;  1JAO A;  5I2Z A;  1CGF A;  1IAB A;  1XFY A;  4ON1 A;  5D2B A;  3KHI A;  1GE5 A;  4H3X A;  4GF1 A;  1IAA A;  1G9K A;  3ZXH A;  1O0T A;  1R1J A;  1SMP A;  3Q2H A;  3ZUK A;  2MLS A;  1JH1 A;  1OM7 A;  2J0T A;  1YP1 A;  1WNI A;  1OM6 A;  1CGL A;  1K7G A;  4DF9 A;  1BQQ M;  1BUD A;  1PWU A;  3K7N A;  1XUD A;  2MZE A;  1USN A;  5D3C A;  1GO7 P;  5L7F A;  1G12 A;  2OY4 A;  3F18 A;  2X3A A;  4AIG A;  2HU6 A;  4A3W A;  2POJ A;  2OW0 A;  1JIW P;  2A8H A;  3O2X A;  3AIG A;  2OI0 A;  1B8Y A;  4GWM A;  1CGE A;  1G49 A;  1OM8 A;  1OMJ A;  1K7I A;  1IAC A;  5CUH A;  1C3I A;  4JPA A;  3LQ0 A;  1UMS A;  3KMC A;  4H82 A;  5D7W A;  1C7K A;  2D1O A;  1XFV A;  1UEA A;  2Y6D A;  1UTT A;  1XFU A;  4GWN A;  1XFX A;  2MZH A;  1CAQ A;  4HX3 A;  2DW2 A;  1QIA A;  2YB9 A;  1D7X A;  2DW1 A;  456C A;  4JQG A;  1XUC A;  1JK3 A;  4EFS A;  1JAQ A;  1KUI A;  2L0R A;  3LJG A;  3DL1 A;  1R1I A;  2XS4 A;  1GKD A;  2RJQ A;  3LEA A;  5H8X A;  4XM7 A;  1D8F A;  2FV5 A;  1JAP A;  3E8R A;  1HTD A;  1HFC A;  3VI1 A;  4IUW A;  1PWQ A;  5I4O A;  4DV8 A;  3GBO A;  1GXD A;  1KBC A;  4DPE A;  1KUK A;  1PWW A;  3KEC A;  3MA2 A;  2XS3 A;  3OHO A;  3N2U A;  1Y8J A;  4GR3 A;  1ROS A;  3G5C A;  2W13 A;  3LK8 A;  2ERQ A;  3TSK A;  4GQL A;  4PKW A;  1SLN A;  1QIB A;  5BOY A;  2MLR A;  1J7N A;  4I03 A; 
#chains in the Genus database with same CATH topology
 3EHY A;  1L6J A;  1SRP A;  3LJT A;  3KME A;  3P1V A;  1CQR A;  1SU3 A;  3TVC A;  4FXQ A;  3HB2 P;  1DMT A;  2USN A;  3AYK A;  1BIW A;  2QPJ A;  3HYG A;  4R3V A;  1BSW A;  1H71 P;  1RM8 A;  3LUN A;  4XBH A;  1FLS A;  2ERP A;  5CXA A;  1K7Q A;  3G42 A;  4L7A A;  3LJZ A;  1YCM A;  3V96 B;  3LIL A;  3Q2G A;  1R54 A;  2X7M A;  2W12 A;  5I0L A;  1XUR A;  2DDY A;  3DTI A;  1I1I P;  1AST A;  1PWP A;  3WV2 A;  1EAK A;  1Y93 A;  3HDB A;  3EDH A;  2DW0 A;  1BM6 A;  1ZS0 A;  2OZR A;  4FXY P;  1EUB A;  3LMC A;  1OS9 A;  3F19 A;  3DTE A;  3LIR A;  4L6T A;  2OXU A;  1ZXC A;  3F15 A;  4FVL A;  4J4M A;  2K2G A;  3DPF A;  1B3D A;  3CKI A;  3LIK A;  3EDG A;  5BOT A;  3UVC A;  2J83 A;  4FU4 A;  2AYK A;  4L63 A;  1HV5 A;  1JJ9 A;  1YQY A;  2JT5 A;  2OW2 A;  2OVZ A;  3KEK A;  3HBV P;  3DTK A;  5LAB A;  2OW1 A;  1OZ9 A;  1ATL A;  1FM1 A;  1QJJ A;  4AXQ A;  2E3X A;  1AYK A;  3DWB A;  4ZR5 A;  3RTS A;  4H84 A;  5CZM A;  2JIH A;  2X3B A;  1GE7 A;  3L0T A;  1UTZ A;  1D5J A;  1GO8 P;  1HY7 A;  1PWV A;  3EWJ A;  3U1R A;  5I12 A;  2ERO A;  1O0Q A;  2TCL A;  3DPE A;  3HBU P;  3NX7 A;  4JA1 A;  4WF6 A;  4GR0 A;  3BA0 A;  1XFW A;  2OVX A;  3F17 A;  3ZVS A;  3LKA A;  1BZS A;  5B5P A;  1JKY A;  2OW9 A;  4WZV A;  3DNG A;  3AYU A;  4G9L A;  4PKQ A;  3WV3 A;  1JIZ A;  3RTT A;  3I7I A;  4A7B A;  4JP4 A;  1MMR A;  5L79 A;  4PKS A;  2KRJ A;  4PKV A;  4AUO A;  2W0D A;  2CLT A;  1UMT A;  3K7L A;  2JSD A;  4GR8 A;  2PJT A;  3USN A;  2E2D A;  3N2V A;  5B5O A;  1MMP A;  4H2E A;  4PKT A;  5I3M A;  1C8T A;  1Y0V A;  2WOA A;  2JNP A;  3EDZ A;  5JMY A;  3EDI A;  1R1H A;  1HOV A;  1BUV M;  1QUA A;  4XCT A;  3B8Z A;  2I47 A;  1A85 A;  5D1S A;  966C A;  1D8M A;  2D1N A;  2WO8 A;  1ND1 A;  3EHX A;  1SAT A;  3WV1 A;  2RJP A;  4CTH A;  1I76 A;  3I7G A;  2JT6 A;  2OY2 A;  4AYK A;  1GKC A;  3LUM A;  4H76 A;  1ZP5 A;  4G0D A;  5D1U A;  3KWV C;  4L19 A;  3TT4 A;  3ELM A;  4IJO A;  1IAE A;  4H1Q A;  2K9C A;  3F16 A;  1G4K A;  2O3E A;  1HFS A;  1ZXV A;  4H49 A;  1ZTQ A;  1ZVX A;  1JAN A;  4DD8 A;  1OS2 A;  1BQO A;  1FBL A;  2OXZ A;  3OHL A;  2V4B A;  2W14 A;  4IN9 A;  1DTH A;  1CK7 A;  1MMB A;  1KAP P;  4GUY A;  1AF0 A;  1AKL A;  3HY9 A;  3SHI A;  3TS4 A;  1RMZ A;  1IAG A;  1BKC I;  1EB6 A;  3HDA P;  2DDF A;  3O64 A;  3LE9 A;  1BKC A;  1A86 A;  1I73 A;  1YOU A;  4QKZ A;  4PKU A;  2YUF A;  1IAD A;  1QJI A;  1TVI A;  2CKI A;  4HMA A;  4Q1L A;  1SLM A;  1CIZ A;  4JIJ A;  3KEJ A;  1R55 A;  1MNC A;  2N8R A;  5D1T A;  3DSL A;  4WKI A;  4ILW D;  2AIG P;  5I43 A;  3KRY A;  1KUG A;  2YIG A;  1XFZ A;  4PKR A;  4WK7 A;  2W15 A;  2WO9 A;  3VTG A;  2OXW A;  3LQB A;  4H30 A;  1KUH A;  1OO9 A;  2MZI A;  1MMQ A;  4XM6 A;  4XM8 A;  2O36 A;  1KUF A;  1G05 A;  3LGP A;  5BPA A;  3HY7 A;  1Z3J A;  2Y6C A;  1S4B P;  4I35 A;  1QIC A;  4WKE A;  3B92 A;  3B2Z A;  830C A;  2Z2D A;  2SRT A;  3P24 A;  3F1A A;  3L0V A;  1GE6 A;  2FV9 A;  1Q3A A;  1BKC E;  2X3C A;  1CXV A;  1JAO A;  5I2Z A;  1CGF A;  1IAB A;  1XFY A;  4ON1 A;  5D2B A;  3KHI A;  1GE5 A;  4H3X A;  4GF1 A;  1IAA A;  1G9K A;  3ZXH A;  1O0T A;  1R1J A;  1SMP A;  3Q2H A;  3ZUK A;  2MLS A;  1JH1 A;  1OM7 A;  2J0T A;  1YP1 A;  1WNI A;  1OM6 A;  1CGL A;  1XM5 A;  1K7G A;  4DF9 A;  1BQQ M;  1BUD A;  1PWU A;  3K7N A;  1XUD A;  2MZE A;  1USN A;  5D3C A;  1GO7 P;  5L7F A;  1G12 A;  2OY4 A;  3F18 A;  2X3A A;  4AIG A;  2HU6 A;  4A3W A;  2POJ A;  1XAX A;  2OW0 A;  1JIW P;  2A8H A;  3O2X A;  3AIG A;  2OI0 A;  1B8Y A;  4GWM A;  1CGE A;  1G49 A;  1OM8 A;  1OMJ A;  1K7I A;  1IAC A;  5CUH A;  1C3I A;  4JPA A;  3LQ0 A;  1UMS A;  3KMC A;  4H82 A;  5D7W A;  1C7K A;  2D1O A;  1XFV A;  1UEA A;  2Y6D A;  1UTT A;  1XFU A;  4GWN A;  1XFX A;  2MZH A;  1CAQ A;  4HX3 A;  2DW2 A;  1QIA A;  2YB9 A;  1D7X A;  2DW1 A;  456C A;  4JQG A;  1XUC A;  1JK3 A;  4EFS A;  1JAQ A;  1KUI A;  2L0R A;  3LJG A;  3DL1 A;  1R1I A;  2XS4 A;  1GKD A;  2RJQ A;  3LEA A;  5H8X A;  4XM7 A;  1D8F A;  2FV5 A;  1JAP A;  3E8R A;  1HTD A;  1HFC A;  3VI1 A;  4IUW A;  1PWQ A;  5I4O A;  4DV8 A;  3GBO A;  1GXD A;  1KBC A;  4DPE A;  1KUK A;  1PWW A;  3KEC A;  3MA2 A;  2XS3 A;  3OHO A;  3N2U A;  1Y8J A;  4GR3 A;  1ROS A;  3G5C A;  2W13 A;  3LK8 A;  2ERQ A;  3TSK A;  4GQL A;  4PKW A;  1SLN A;  1QIB A;  5BOY A;  2MLR A;  1J7N A;  4I03 A; 
#chains in the Genus database with same CATH homology
 3EHY A;  1L6J A;  1SRP A;  3LJT A;  3KME A;  3P1V A;  1CQR A;  1SU3 A;  3TVC A;  4FXQ A;  3HB2 P;  1DMT A;  2USN A;  3AYK A;  1BIW A;  2QPJ A;  3HYG A;  4R3V A;  1BSW A;  1H71 P;  1RM8 A;  3LUN A;  4XBH A;  1FLS A;  2ERP A;  5CXA A;  1K7Q A;  3G42 A;  4L7A A;  3LJZ A;  1YCM A;  3V96 B;  3LIL A;  3Q2G A;  1R54 A;  2X7M A;  2W12 A;  5I0L A;  1XUR A;  2DDY A;  3DTI A;  1I1I P;  1AST A;  1PWP A;  3WV2 A;  1EAK A;  1Y93 A;  3HDB A;  3EDH A;  2DW0 A;  1BM6 A;  1ZS0 A;  2OZR A;  4FXY P;  1EUB A;  3LMC A;  1OS9 A;  3F19 A;  3DTE A;  3LIR A;  4L6T A;  2OXU A;  1ZXC A;  3F15 A;  4FVL A;  4J4M A;  2K2G A;  3DPF A;  1B3D A;  3CKI A;  3LIK A;  3EDG A;  5BOT A;  3UVC A;  2J83 A;  4FU4 A;  2AYK A;  4L63 A;  1HV5 A;  1JJ9 A;  1YQY A;  2JT5 A;  2OW2 A;  2OVZ A;  3KEK A;  3HBV P;  3DTK A;  5LAB A;  2OW1 A;  1ATL A;  1FM1 A;  1QJJ A;  4AXQ A;  2E3X A;  1AYK A;  3DWB A;  4ZR5 A;  3RTS A;  4H84 A;  5CZM A;  2JIH A;  2X3B A;  1GE7 A;  3L0T A;  1UTZ A;  1D5J A;  1GO8 P;  1HY7 A;  1PWV A;  3EWJ A;  3U1R A;  5I12 A;  2ERO A;  1O0Q A;  2TCL A;  3DPE A;  3HBU P;  3NX7 A;  4JA1 A;  4WF6 A;  4GR0 A;  3BA0 A;  1XFW A;  2OVX A;  3F17 A;  3ZVS A;  3LKA A;  1BZS A;  5B5P A;  1JKY A;  2OW9 A;  4WZV A;  3DNG A;  3AYU A;  4G9L A;  4PKQ A;  3WV3 A;  1JIZ A;  3RTT A;  3I7I A;  4A7B A;  4JP4 A;  1MMR A;  5L79 A;  4PKS A;  2KRJ A;  4PKV A;  4AUO A;  2W0D A;  2CLT A;  1UMT A;  3K7L A;  2JSD A;  4GR8 A;  2PJT A;  3USN A;  2E2D A;  3N2V A;  5B5O A;  1MMP A;  4H2E A;  4PKT A;  5I3M A;  1C8T A;  1Y0V A;  2WOA A;  2JNP A;  3EDZ A;  5JMY A;  3EDI A;  1R1H A;  1HOV A;  1BUV M;  1QUA A;  4XCT A;  3B8Z A;  2I47 A;  1A85 A;  5D1S A;  966C A;  1D8M A;  2D1N A;  2WO8 A;  1ND1 A;  3EHX A;  1SAT A;  3WV1 A;  2RJP A;  4CTH A;  1I76 A;  3I7G A;  2JT6 A;  2OY2 A;  4AYK A;  1GKC A;  3LUM A;  4H76 A;  1ZP5 A;  4G0D A;  5D1U A;  3KWV C;  4L19 A;  3TT4 A;  3ELM A;  4IJO A;  1IAE A;  4H1Q A;  2K9C A;  3F16 A;  1G4K A;  2O3E A;  1HFS A;  1ZXV A;  4H49 A;  1ZTQ A;  1ZVX A;  1JAN A;  4DD8 A;  1OS2 A;  1BQO A;  1FBL A;  2OXZ A;  3OHL A;  2V4B A;  2W14 A;  4IN9 A;  1DTH A;  1CK7 A;  1MMB A;  1KAP P;  4GUY A;  1AF0 A;  1AKL A;  3HY9 A;  3SHI A;  3TS4 A;  1RMZ A;  1IAG A;  1BKC I;  1EB6 A;  3HDA P;  2DDF A;  3O64 A;  3LE9 A;  1BKC A;  1A86 A;  1I73 A;  1YOU A;  4QKZ A;  4PKU A;  2YUF A;  1IAD A;  1QJI A;  2CKI A;  4HMA A;  4Q1L A;  1SLM A;  1CIZ A;  4JIJ A;  3KEJ A;  1R55 A;  1MNC A;  2N8R A;  5D1T A;  3DSL A;  4WKI A;  4ILW D;  2AIG P;  5I43 A;  3KRY A;  1KUG A;  2YIG A;  1XFZ A;  4PKR A;  4WK7 A;  2W15 A;  2WO9 A;  3VTG A;  2OXW A;  3LQB A;  4H30 A;  1KUH A;  1OO9 A;  2MZI A;  1MMQ A;  4XM6 A;  4XM8 A;  2O36 A;  1KUF A;  1G05 A;  3LGP A;  5BPA A;  3HY7 A;  1Z3J A;  2Y6C A;  1S4B P;  4I35 A;  1QIC A;  4WKE A;  3B92 A;  3B2Z A;  830C A;  2Z2D A;  2SRT A;  3P24 A;  3F1A A;  3L0V A;  1GE6 A;  2FV9 A;  1Q3A A;  1BKC E;  2X3C A;  1CXV A;  1JAO A;  5I2Z A;  1CGF A;  1IAB A;  1XFY A;  4ON1 A;  5D2B A;  3KHI A;  1GE5 A;  4H3X A;  4GF1 A;  1IAA A;  1G9K A;  3ZXH A;  1O0T A;  1R1J A;  1SMP A;  3Q2H A;  3ZUK A;  2MLS A;  1JH1 A;  1OM7 A;  2J0T A;  1YP1 A;  1WNI A;  1OM6 A;  1CGL A;  1K7G A;  4DF9 A;  1BQQ M;  1BUD A;  1PWU A;  3K7N A;  1XUD A;  2MZE A;  1USN A;  5D3C A;  1GO7 P;  5L7F A;  1G12 A;  2OY4 A;  3F18 A;  2X3A A;  4AIG A;  2HU6 A;  4A3W A;  2POJ A;  2OW0 A;  1JIW P;  2A8H A;  3O2X A;  3AIG A;  2OI0 A;  1B8Y A;  4GWM A;  1CGE A;  1G49 A;  1OM8 A;  1OMJ A;  1K7I A;  1IAC A;  5CUH A;  1C3I A;  4JPA A;  3LQ0 A;  1UMS A;  3KMC A;  4H82 A;  5D7W A;  1C7K A;  2D1O A;  1XFV A;  1UEA A;  2Y6D A;  1UTT A;  1XFU A;  4GWN A;  1XFX A;  2MZH A;  1CAQ A;  4HX3 A;  2DW2 A;  1QIA A;  2YB9 A;  1D7X A;  2DW1 A;  456C A;  4JQG A;  1XUC A;  1JK3 A;  4EFS A;  1JAQ A;  1KUI A;  2L0R A;  3LJG A;  3DL1 A;  1R1I A;  2XS4 A;  1GKD A;  2RJQ A;  3LEA A;  5H8X A;  4XM7 A;  1D8F A;  2FV5 A;  1JAP A;  3E8R A;  1HTD A;  1HFC A;  3VI1 A;  4IUW A;  1PWQ A;  5I4O A;  4DV8 A;  3GBO A;  1GXD A;  1KBC A;  4DPE A;  1KUK A;  1PWW A;  3KEC A;  3MA2 A;  2XS3 A;  3OHO A;  3N2U A;  1Y8J A;  4GR3 A;  1ROS A;  3G5C A;  2W13 A;  3LK8 A;  2ERQ A;  3TSK A;  4GQL A;  4PKW A;  1SLN A;  1QIB A;  5BOY A;  2MLR A;  1J7N A;  4I03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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