4GR0A

Crystal structure of the catalytic domain of human mmp12 in complex with selective phosphinic inhibitor rxp470b
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies.
pubmed doi rcsb
molecule keywords Macrophage metalloelastase
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 45
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4gr0A00
4GR3A 4I35A 2XS4A 1ATLA 3EWJA 1L6JA 4HX3A 1OO9A 2E2DA 3UVCA 2ERPA 966CA 5I2ZA 2JSDA 3I7GA 4GR0A 1MMQA 1KUKA 3NX7A 4PKVA 3LILA 1BKCA 1BZSA 1Y8JA 1IAGA 1HFSA 2XS3A 4AIGA 4ON1A 2DW2A 3TT4A 1MMPA 2X3BA 2I47A 3AIGA 2K2GA 1BUVM 3N2UA 1G9KA 1GE7A 3U1RA 456CA 3KMCA 1KBCA 3WV1A 3DSLA 1KUFA 3EDIA 4H84A 1SATA 1SRPA 2OXWA 4HMAA 4JP4A 3RTTA 1BUDA 1OS2A 2OW2A 1JAQA 4J4MA 5CUHA 1HFCA 5D2BA 2OZRA 1O0TA 4H2EA 1JH1A 3LKAA 3EDHA 5L79A 1BM6A 4AUOA 1D8MA 2YIGA 1AYKA 1EUBA 1CIZA 2WO8A 4XBHA 3LJGA 5CZMA 4PKSA 5CXAA 1KUHA 3LIKA 1D5JA 2SRTA 3K7LA 4G0DA 2DDYA 1FLSA 4H30A 4AYKA 3VTGA 4XM6A 2POJA 2N8RA 3LUNA 4PKRA 2MZIA 4XM8A 2JT5A 2OXUA 1QJJA 2OW9A 3HY7A 1OS9A 3N2VA 2TCLA 1GXDA 1BKCE 1ND1A 5BPAA 1QUAA 4JIJA 3DWBA 2OW0A 2PJTA 1R54A 4GQLA 4H49A 3OHOA 3TSKA 2Y6CA 2JIHA 3WV3A 3HDAP 5B5OA 3K7NA 2USNA 2MLSA 3L0TA 3KEKA 3USNA 1UTTA 1ZXCA 3BA0A 5D1UA 4A7BA 3LQ0A 1G05A 4G9LA 4I03A 4FXQA 1Q3AA 1YCMA 2MZEA 4FVLA 1SMPA 2A8HA 1UMSA 1AKLA 1XFWA 4DPEA 4H76A 1J7NA 1D7XA 2DW1A 3DPEA 1ZTQA 4WF6A 1GKDA 1GO8P 1EAKA 1XFUA 2D1OA 1R1IA 1C7KA 5L7FA 3ZUKA 1KUIA 2E3XA 2O3EA 3E8RA 5I43A 1HOVA 1R1JA 1ZS0A 1FM1A 5B5PA 2WOAA 3G42A 4L63A 2YB9A 3O2XA 1K7GA 2AIGP 3L0VA 2OW1A 2OVZA 1ASTA 2W0DA 2O36A 3DNGA 5LABA 4GF1A 4PKTA 3HYGA 1JK3A 2DDFA 1IABA 830CA 2QPJA 2WO9A 4A3WA 4GWNA 4PKWA 1D8FA 1SLNA 3P1VA 4FU4A 1PWVA 2OXZA 1UMTA 1HV5A 1Z3JA 4WKIA 1CAQA 4DD8A 3ELMA 2OVXA 4JA1A 5I12A 1DTHA 2L0RA 1CXVA 4L19A 1IAEA 1PWPA 1K7IA 3LEAA 3HDBA 5JMYA 1PWQA 1XFYA 4QKZA 4IUWA 1CGEA 1JIWP 1Y93A 2CKIA 2FV5A 2MZHA 3OHLA 4JQGA 3LJZA 3MA2A 1GE5A 1I76A 3KRYA 3KECA 3V96B 1CK7A 1I73A 1CGFA 4WZVA 4XCTA 2J0TA 1PWWA 2K9CA 5BOYA 1GE6A 1BSWA 4AXQA 4DV8A 4H1QA 3GBOA 3EDGA 1BQOA 3EDZA 3VI1A 2OY4A 2ERQA 2DW0A 1JAPA 1JANA 3LQBA 1B8YA 1XFVA 4ZR5A 3F16A 1A86A 3KHIA 1JJ9A 3F15A 2HU6A 3EHYA 1OM6A 2Z2DA 1JIZA 1CQRA 1R55A 1QIAA 1KUGA 1UTZA 1KAPP 4R3VA 5D3CA 1USNA 1K7QA 2CLTA 1MMRA 3CKIA 1DMTA 1IACA 5H8XA 3LE9A 5BOTA 1OM8A 1O0QA 4GUYA 3LJTA 1ROSA 1H71P 1G49A 1JKYA 3F17A 3SHIA 4L6TA 4EFSA 1ZP5A 4ILWD 3AYUA 2J83A 3Q2GA 5D7WA 1G12A 4XM7A 1Y0VA 1BQQM 1B3DA 5D1SA 1HY7A 4WK7A 2FV9A 3AYKA 3P24A 2OY2A 1I1IP 1XUCA 3WV2A 3B92A 1BKCI 5I0LA 2EROA 2JNPA 3KEJA 1ZVXA 5D1TA 4DF9A 3F18A 3EHXA 3B2ZA 3HBUP 1XURA 4IN9A 1SLMA 1OMJA 2X3AA 4H82A 2W14A 3LGPA 1AF0A 4GR8A 1FBLA 1XFZA 2Y6DA 3G5CA 3DL1A 4FXYP 3KWVC 1G4KA 3HB2P 3ZVSA 1YOUA 3HBVP 3I7IA 1IAAA 3O64A 1R1HA 2X3CA 3LK8A 1A85A 2X7MA 1XUDA 2KRJA 1RM8A 4PKUA 4PKQA 1SU3A 4WKEA 1WNIA 1S4BP 3F19A 3Q2HA 1BIWA 1HTDA 1YQYA 3HY9A 3TVCA 1QICA 3TS4A 1UEAA 3LUMA 2OI0A 1QJIA 3LIRA 2W12A 2V4BA 1C3IA 1RMZA 1CGLA 4GWMA 5I4OA 2W15A 1XFXA 1PWUA 3KMEA 1YP1A 2D1NA 2RJQA 4Q1LA 2AYKA 1EB6A 2MLRA 4JPAA 3B8ZA 3RTSA 5I3MA 1JAOA 2JT6A 4H3XA 2W13A 1C8TA 1ZXVA 1OM7A 3F1AA 1GO7P 4CTHA 1QIBA 1IADA 4IJOA 1GKCA 2RJPA 1MMBA 1MNCA 3ZXHA 3LMCA 3DPFA
chains in the Genus database with same CATH superfamily
4GR3A 4I35A 2XS4A 1ATLA 3EWJA 1L6JA 4HX3A 1OO9A 2E2DA 3UVCA 2ERPA 966CA 5I2ZA 2JSDA 3I7GA 4GR0A 1MMQA 1KUKA 3NX7A 4PKVA 3LILA 1BKCA 1BZSA 1Y8JA 1IAGA 1HFSA 2XS3A 4AIGA 4ON1A 2DW2A 3TT4A 1MMPA 2X3BA 2I47A 3AIGA 2K2GA 1BUVM 1XAXA 3N2UA 1G9KA 1GE7A 3U1RA 456CA 3KMCA 1KBCA 3WV1A 3DSLA 1KUFA 3EDIA 4H84A 1SATA 1SRPA 2OXWA 4HMAA 4JP4A 3RTTA 1BUDA 1OS2A 2OW2A 1JAQA 4J4MA 5CUHA 1HFCA 5D2BA 2OZRA 1O0TA 4H2EA 1JH1A 3LKAA 3EDHA 5L79A 1BM6A 4AUOA 1D8MA 2YIGA 1AYKA 1EUBA 1CIZA 2WO8A 4XBHA 3LJGA 5CZMA 4PKSA 5CXAA 1KUHA 3LIKA 1D5JA 2SRTA 3K7LA 4G0DA 2DDYA 1FLSA 4H30A 4AYKA 3VTGA 4XM6A 2POJA 2N8RA 3LUNA 4PKRA 2MZIA 4XM8A 2JT5A 2OXUA 1QJJA 2OW9A 3HY7A 1OS9A 3N2VA 2TCLA 1GXDA 1BKCE 1ND1A 5BPAA 1QUAA 4JIJA 3DWBA 2OW0A 2PJTA 1R54A 4GQLA 4H49A 3OHOA 3TSKA 2Y6CA 2JIHA 3WV3A 3HDAP 5B5OA 3K7NA 2USNA 2MLSA 3L0TA 3KEKA 3USNA 1UTTA 1ZXCA 3BA0A 5D1UA 4A7BA 3LQ0A 1G05A 4G9LA 4I03A 4FXQA 1Q3AA 1YCMA 2MZEA 4FVLA 1SMPA 2A8HA 1UMSA 1AKLA 1XFWA 4DPEA 2YUFA 4H76A 1J7NA 1D7XA 2DW1A 3DPEA 1ZTQA 4WF6A 1GKDA 1GO8P 1EAKA 1XFUA 2D1OA 1R1IA 1C7KA 5L7FA 3ZUKA 1KUIA 2E3XA 2O3EA 3E8RA 5I43A 1HOVA 1R1JA 1ZS0A 1FM1A 5B5PA 2WOAA 3G42A 4L63A 2YB9A 3O2XA 1K7GA 2AIGP 3L0VA 2OW1A 2OVZA 1ASTA 2W0DA 2O36A 3DNGA 5LABA 4GF1A 4PKTA 3HYGA 3DTEA 1JK3A 2DDFA 1IABA 830CA 2QPJA 2WO9A 4A3WA 4GWNA 4PKWA 1D8FA 1SLNA 3P1VA 4FU4A 1PWVA 2OXZA 1UMTA 1HV5A 1Z3JA 4WKIA 1CAQA 4DD8A 3ELMA 2OVXA 4JA1A 5I12A 1DTHA 2L0RA 1CXVA 4L19A 1IAEA 1PWPA 1K7IA 3LEAA 3HDBA 5JMYA 1PWQA 1XFYA 4QKZA 4IUWA 1CGEA 1JIWP 1Y93A 2CKIA 2FV5A 2MZHA 3OHLA 4JQGA 3LJZA 3MA2A 1GE5A 1I76A 3KRYA 3KECA 3V96B 1CK7A 1I73A 1CGFA 4WZVA 4XCTA 2J0TA 1PWWA 2K9CA 5BOYA 1GE6A 1BSWA 4AXQA 4DV8A 4H1QA 3GBOA 3EDGA 1BQOA 3EDZA 3VI1A 2OY4A 2ERQA 2DW0A 1JAPA 1JANA 3LQBA 1B8YA 1XFVA 4ZR5A 3F16A 1A86A 3KHIA 1JJ9A 3F15A 2HU6A 3EHYA 1OM6A 2Z2DA 1JIZA 1OZ9A 1CQRA 1R55A 1QIAA 1KUGA 1UTZA 1KAPP 4R3VA 5D3CA 1USNA 1K7QA 2CLTA 1MMRA 3CKIA 1DMTA 1IACA 5H8XA 3LE9A 5BOTA 1OM8A 1O0QA 4GUYA 3LJTA 1ROSA 1H71P 1G49A 1JKYA 3F17A 3SHIA 4L6TA 4EFSA 1TVIA 1ZP5A 4L7AA 4ILWD 3AYUA 2J83A 3Q2GA 5D7WA 1G12A 4XM7A 1Y0VA 1BQQM 1B3DA 5D1SA 1HY7A 4WK7A 2FV9A 3AYKA 3P24A 2OY2A 1I1IP 1XUCA 3WV2A 3B92A 1BKCI 5I0LA 2EROA 2JNPA 3KEJA 1ZVXA 5D1TA 4DF9A 3F18A 3EHXA 3B2ZA 3HBUP 1XURA 4IN9A 1SLMA 1OMJA 2X3AA 4H82A 2W14A 3LGPA 1AF0A 4GR8A 1FBLA 1XFZA 3DTIA 2Y6DA 3G5CA 1XM5A 3DL1A 4FXYP 3KWVC 1G4KA 3HB2P 3ZVSA 1YOUA 3HBVP 3I7IA 1IAAA 3O64A 1R1HA 2X3CA 3LK8A 1A85A 2X7MA 1XUDA 2KRJA 1RM8A 4PKUA 4PKQA 1SU3A 4WKEA 1WNIA 1S4BP 3F19A 3Q2HA 1BIWA 1HTDA 1YQYA 3HY9A 3TVCA 1QICA 3TS4A 1UEAA 3LUMA 2OI0A 3DTKA 1QJIA 3LIRA 2W12A 2V4BA 1C3IA 1RMZA 1CGLA 4GWMA 5I4OA 2W15A 1XFXA 1PWUA 3KMEA 1YP1A 2D1NA 2RJQA 4Q1LA 2AYKA 1EB6A 2MLRA 4JPAA 3B8ZA 3RTSA 5I3MA 1JAOA 2JT6A 4H3XA 2W13A 1C8TA 1ZXVA 1OM7A 3F1AA 1GO7P 4CTHA 1QIBA 1IADA 4IJOA 1GKCA 2RJPA 1MMBA 1MNCA 3ZXHA 3LMCA 3DPFA
chains in the Genus database with same CATH topology
4GR3A 4I35A 2XS4A 1ATLA 3EWJA 1L6JA 4HX3A 1OO9A 2E2DA 3UVCA 2ERPA 966CA 5I2ZA 2JSDA 3I7GA 4GR0A 1MMQA 1KUKA 3NX7A 4PKVA 3LILA 1BKCA 1BZSA 1Y8JA 1IAGA 1HFSA 2XS3A 4AIGA 4ON1A 2DW2A 3TT4A 1MMPA 2X3BA 2I47A 3AIGA 2K2GA 1BUVM 3N2UA 1G9KA 1GE7A 3U1RA 456CA 3KMCA 1KBCA 3WV1A 3DSLA 1KUFA 3EDIA 4H84A 1SATA 1SRPA 2OXWA 4HMAA 4JP4A 3RTTA 1BUDA 1OS2A 2OW2A 1JAQA 4J4MA 5CUHA 1HFCA 5D2BA 2OZRA 1O0TA 4H2EA 1JH1A 3LKAA 3EDHA 5L79A 1BM6A 4AUOA 1D8MA 2YIGA 1AYKA 1EUBA 1CIZA 2WO8A 4XBHA 3LJGA 5CZMA 4PKSA 5CXAA 1KUHA 3LIKA 1D5JA 2SRTA 3K7LA 4G0DA 2DDYA 1FLSA 4H30A 4AYKA 3VTGA 4XM6A 2POJA 2N8RA 3LUNA 4PKRA 2MZIA 4XM8A 2JT5A 2OXUA 1QJJA 2OW9A 3HY7A 1OS9A 3N2VA 2TCLA 1GXDA 1BKCE 1ND1A 5BPAA 1QUAA 4JIJA 3DWBA 2OW0A 2PJTA 1R54A 4GQLA 4H49A 3OHOA 3TSKA 2Y6CA 2JIHA 3WV3A 3HDAP 5B5OA 3K7NA 2USNA 2MLSA 3L0TA 3KEKA 3USNA 1UTTA 1ZXCA 3BA0A 5D1UA 4A7BA 3LQ0A 1G05A 4G9LA 4I03A 4FXQA 1Q3AA 1YCMA 2MZEA 4FVLA 1SMPA 2A8HA 1UMSA 1AKLA 1XFWA 4DPEA 2YUFA 4H76A 1J7NA 1D7XA 2DW1A 3DPEA 1ZTQA 4WF6A 1GKDA 1GO8P 1EAKA 1XFUA 2D1OA 1R1IA 1C7KA 5L7FA 3ZUKA 1KUIA 2E3XA 2O3EA 3E8RA 5I43A 1HOVA 1R1JA 1ZS0A 1FM1A 5B5PA 2WOAA 3G42A 4L63A 2YB9A 3O2XA 1K7GA 2AIGP 3L0VA 2OW1A 2OVZA 1ASTA 2W0DA 2O36A 3DNGA 5LABA 4GF1A 4PKTA 3HYGA 3DTEA 1JK3A 2DDFA 1IABA 830CA 2QPJA 2WO9A 4A3WA 4GWNA 4PKWA 1D8FA 1SLNA 3P1VA 4FU4A 1PWVA 2OXZA 1UMTA 1HV5A 1Z3JA 4WKIA 1CAQA 4DD8A 3ELMA 2OVXA 4JA1A 5I12A 1DTHA 2L0RA 1CXVA 4L19A 1IAEA 1PWPA 1K7IA 3LEAA 3HDBA 5JMYA 1PWQA 1XFYA 4QKZA 4IUWA 1CGEA 1JIWP 1Y93A 2CKIA 2FV5A 2MZHA 3OHLA 4JQGA 3LJZA 3MA2A 1GE5A 1I76A 3KRYA 3KECA 3V96B 1CK7A 1I73A 1CGFA 4WZVA 4XCTA 2J0TA 1PWWA 2K9CA 5BOYA 1GE6A 1BSWA 4AXQA 4DV8A 4H1QA 3GBOA 3EDGA 1BQOA 3EDZA 3VI1A 2OY4A 2ERQA 2DW0A 1JAPA 1JANA 3LQBA 1B8YA 1XFVA 4ZR5A 3F16A 1A86A 3KHIA 1JJ9A 3F15A 2HU6A 3EHYA 1OM6A 2Z2DA 1JIZA 1CQRA 1R55A 1QIAA 1KUGA 1UTZA 1KAPP 4R3VA 5D3CA 1USNA 1K7QA 2CLTA 1MMRA 3CKIA 1DMTA 1IACA 5H8XA 3LE9A 5BOTA 1OM8A 1O0QA 4GUYA 3LJTA 1ROSA 1H71P 1G49A 1JKYA 3F17A 3SHIA 4L6TA 4EFSA 1ZP5A 4L7AA 4ILWD 3AYUA 2J83A 3Q2GA 5D7WA 1G12A 4XM7A 1Y0VA 1BQQM 1B3DA 5D1SA 1HY7A 4WK7A 2FV9A 3AYKA 3P24A 2OY2A 1I1IP 1XUCA 3WV2A 3B92A 1BKCI 5I0LA 2EROA 2JNPA 3KEJA 1ZVXA 5D1TA 4DF9A 3F18A 3EHXA 3B2ZA 3HBUP 1XURA 4IN9A 1SLMA 1OMJA 2X3AA 4H82A 2W14A 3LGPA 1AF0A 4GR8A 1FBLA 1XFZA 3DTIA 2Y6DA 3G5CA 3DL1A 4FXYP 3KWVC 1G4KA 3HB2P 3ZVSA 1YOUA 3HBVP 3I7IA 1IAAA 3O64A 1R1HA 2X3CA 3LK8A 1A85A 2X7MA 1XUDA 2KRJA 1RM8A 4PKUA 4PKQA 1SU3A 4WKEA 1WNIA 1S4BP 3F19A 3Q2HA 1BIWA 1HTDA 1YQYA 3HY9A 3TVCA 1QICA 3TS4A 1UEAA 3LUMA 2OI0A 3DTKA 1QJIA 3LIRA 2W12A 2V4BA 1C3IA 1RMZA 1CGLA 4GWMA 5I4OA 2W15A 1XFXA 1PWUA 3KMEA 1YP1A 2D1NA 2RJQA 4Q1LA 2AYKA 1EB6A 2MLRA 4JPAA 3B8ZA 3RTSA 5I3MA 1JAOA 2JT6A 4H3XA 2W13A 1C8TA 1ZXVA 1OM7A 3F1AA 1GO7P 4CTHA 1QIBA 1IADA 4IJOA 1GKCA 2RJPA 1MMBA 1MNCA 3ZXHA 3LMCA 3DPFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GR3 A;  4I35 A;  2XS4 A;  1ATL A;  3EWJ A;  1L6J A;  4HX3 A;  1OO9 A;  2E2D A;  3UVC A;  2ERP A;  966C A;  5I2Z A;  2JSD A;  3I7G A;  4GR0 A;  1MMQ A;  1KUK A;  3NX7 A;  4PKV A;  3LIL A;  1BKC A;  1BZS A;  1Y8J A;  1IAG A;  1HFS A;  2XS3 A;  4AIG A;  4ON1 A;  2DW2 A;  3TT4 A;  1MMP A;  2X3B A;  2I47 A;  3AIG A;  2K2G A;  1BUV M;  3N2U A;  1G9K A;  1GE7 A;  3U1R A;  456C A;  3KMC A;  1KBC A;  3WV1 A;  3DSL A;  1KUF A;  3EDI A;  4H84 A;  1SAT A;  1SRP A;  2OXW A;  4HMA A;  4JP4 A;  3RTT A;  1BUD A;  1OS2 A;  2OW2 A;  1JAQ A;  4J4M A;  5CUH A;  1HFC A;  5D2B A;  2OZR A;  1O0T A;  4H2E A;  1JH1 A;  3LKA A;  3EDH A;  5L79 A;  1BM6 A;  4AUO A;  1D8M A;  2YIG A;  1AYK A;  1EUB A;  1CIZ A;  2WO8 A;  4XBH A;  3LJG A;  5CZM A;  4PKS A;  5CXA A;  1KUH A;  3LIK A;  1D5J A;  2SRT A;  3K7L A;  4G0D A;  2DDY A;  1FLS A;  4H30 A;  4AYK A;  3VTG A;  4XM6 A;  2POJ A;  2N8R A;  3LUN A;  4PKR A;  2MZI A;  4XM8 A;  2JT5 A;  2OXU A;  1QJJ A;  2OW9 A;  3HY7 A;  1OS9 A;  3N2V A;  2TCL A;  1GXD A;  1BKC E;  1ND1 A;  5BPA A;  1QUA A;  4JIJ A;  3DWB A;  2OW0 A;  2PJT A;  1R54 A;  4GQL A;  4H49 A;  3OHO A;  3TSK A;  2Y6C A;  2JIH A;  3WV3 A;  3HDA P;  5B5O A;  3K7N A;  2USN A;  2MLS A;  3L0T A;  3KEK A;  3USN A;  1UTT A;  1ZXC A;  3BA0 A;  5D1U A;  4A7B A;  3LQ0 A;  1G05 A;  4G9L A;  4I03 A;  4FXQ A;  1Q3A A;  1YCM A;  2MZE A;  4FVL A;  1SMP A;  2A8H A;  1UMS A;  1AKL A;  1XFW A;  4DPE A;  4H76 A;  1J7N A;  1D7X A;  2DW1 A;  3DPE A;  1ZTQ A;  4WF6 A;  1GKD A;  1GO8 P;  1EAK A;  1XFU A;  2D1O A;  1R1I A;  1C7K A;  5L7F A;  3ZUK A;  1KUI A;  2E3X A;  2O3E A;  3E8R A;  5I43 A;  1HOV A;  1R1J A;  1ZS0 A;  1FM1 A;  5B5P A;  2WOA A;  3G42 A;  4L63 A;  2YB9 A;  3O2X A;  1K7G A;  2AIG P;  3L0V A;  2OW1 A;  2OVZ A;  1AST A;  2W0D A;  2O36 A;  3DNG A;  5LAB A;  4GF1 A;  4PKT A;  3HYG A;  1JK3 A;  2DDF A;  1IAB A;  830C A;  2QPJ A;  2WO9 A;  4A3W A;  4GWN A;  4PKW A;  1D8F A;  1SLN A;  3P1V A;  4FU4 A;  1PWV A;  2OXZ A;  1UMT A;  1HV5 A;  1Z3J A;  4WKI A;  1CAQ A;  4DD8 A;  3ELM A;  2OVX A;  4JA1 A;  5I12 A;  1DTH A;  2L0R A;  1CXV A;  4L19 A;  1IAE A;  1PWP A;  1K7I A;  3LEA A;  3HDB A;  5JMY A;  1PWQ A;  1XFY A;  4QKZ A;  4IUW A;  1CGE A;  1JIW P;  1Y93 A;  2CKI A;  2FV5 A;  2MZH A;  3OHL A;  4JQG A;  3LJZ A;  3MA2 A;  1GE5 A;  1I76 A;  3KRY A;  3KEC A;  3V96 B;  1CK7 A;  1I73 A;  1CGF A;  4WZV A;  4XCT A;  2J0T A;  1PWW A;  2K9C A;  5BOY A;  1GE6 A;  1BSW A;  4AXQ A;  4DV8 A;  4H1Q A;  3GBO A;  3EDG A;  1BQO A;  3EDZ A;  3VI1 A;  2OY4 A;  2ERQ A;  2DW0 A;  1JAP A;  1JAN A;  3LQB A;  1B8Y A;  1XFV A;  4ZR5 A;  3F16 A;  1A86 A;  3KHI A;  1JJ9 A;  3F15 A;  2HU6 A;  3EHY A;  1OM6 A;  2Z2D A;  1JIZ A;  1CQR A;  1R55 A;  1QIA A;  1KUG A;  1UTZ A;  1KAP P;  4R3V A;  5D3C A;  1USN A;  1K7Q A;  2CLT A;  1MMR A;  3CKI A;  1DMT A;  1IAC A;  5H8X A;  3LE9 A;  5BOT A;  1OM8 A;  1O0Q A;  4GUY A;  3LJT A;  1ROS A;  1H71 P;  1G49 A;  1JKY A;  3F17 A;  3SHI A;  4L6T A;  4EFS A;  1ZP5 A;  4ILW D;  3AYU A;  2J83 A;  3Q2G A;  5D7W A;  1G12 A;  4XM7 A;  1Y0V A;  1BQQ M;  1B3D A;  5D1S A;  1HY7 A;  4WK7 A;  2FV9 A;  3AYK A;  3P24 A;  2OY2 A;  1I1I P;  1XUC A;  3WV2 A;  3B92 A;  1BKC I;  5I0L A;  2ERO A;  2JNP A;  3KEJ A;  1ZVX A;  5D1T A;  4DF9 A;  3F18 A;  3EHX A;  3B2Z A;  3HBU P;  1XUR A;  4IN9 A;  1SLM A;  1OMJ A;  2X3A A;  4H82 A;  2W14 A;  3LGP A;  1AF0 A;  4GR8 A;  1FBL A;  1XFZ A;  2Y6D A;  3G5C A;  3DL1 A;  4FXY P;  3KWV C;  1G4K A;  3HB2 P;  3ZVS A;  1YOU A;  3HBV P;  3I7I A;  1IAA A;  3O64 A;  1R1H A;  2X3C A;  3LK8 A;  1A85 A;  2X7M A;  1XUD A;  2KRJ A;  1RM8 A;  4PKU A;  4PKQ A;  1SU3 A;  4WKE A;  1WNI A;  1S4B P;  3F19 A;  3Q2H A;  1BIW A;  1HTD A;  1YQY A;  3HY9 A;  3TVC A;  1QIC A;  3TS4 A;  1UEA A;  3LUM A;  2OI0 A;  1QJI A;  3LIR A;  2W12 A;  2V4B A;  1C3I A;  1RMZ A;  1CGL A;  4GWM A;  5I4O A;  2W15 A;  1XFX A;  1PWU A;  3KME A;  1YP1 A;  2D1N A;  2RJQ A;  4Q1L A;  2AYK A;  1EB6 A;  2MLR A;  4JPA A;  3B8Z A;  3RTS A;  5I3M A;  1JAO A;  2JT6 A;  4H3X A;  2W13 A;  1C8T A;  1ZXV A;  1OM7 A;  3F1A A;  1GO7 P;  4CTH A;  1QIB A;  1IAD A;  4IJO A;  1GKC A;  2RJP A;  1MMB A;  1MNC A;  3ZXH A;  3LMC A;  3DPF A; 
#chains in the Genus database with same CATH topology
 4GR3 A;  4I35 A;  2XS4 A;  1ATL A;  3EWJ A;  1L6J A;  4HX3 A;  1OO9 A;  2E2D A;  3UVC A;  2ERP A;  966C A;  5I2Z A;  2JSD A;  3I7G A;  4GR0 A;  1MMQ A;  1KUK A;  3NX7 A;  4PKV A;  3LIL A;  1BKC A;  1BZS A;  1Y8J A;  1IAG A;  1HFS A;  2XS3 A;  4AIG A;  4ON1 A;  2DW2 A;  3TT4 A;  1MMP A;  2X3B A;  2I47 A;  3AIG A;  2K2G A;  1BUV M;  1XAX A;  3N2U A;  1G9K A;  1GE7 A;  3U1R A;  456C A;  3KMC A;  1KBC A;  3WV1 A;  3DSL A;  1KUF A;  3EDI A;  4H84 A;  1SAT A;  1SRP A;  2OXW A;  4HMA A;  4JP4 A;  3RTT A;  1BUD A;  1OS2 A;  2OW2 A;  1JAQ A;  4J4M A;  5CUH A;  1HFC A;  5D2B A;  2OZR A;  1O0T A;  4H2E A;  1JH1 A;  3LKA A;  3EDH A;  5L79 A;  1BM6 A;  4AUO A;  1D8M A;  2YIG A;  1AYK A;  1EUB A;  1CIZ A;  2WO8 A;  4XBH A;  3LJG A;  5CZM A;  4PKS A;  5CXA A;  1KUH A;  3LIK A;  1D5J A;  2SRT A;  3K7L A;  4G0D A;  2DDY A;  1FLS A;  4H30 A;  4AYK A;  3VTG A;  4XM6 A;  2POJ A;  2N8R A;  3LUN A;  4PKR A;  2MZI A;  4XM8 A;  2JT5 A;  2OXU A;  1QJJ A;  2OW9 A;  3HY7 A;  1OS9 A;  3N2V A;  2TCL A;  1GXD A;  1BKC E;  1ND1 A;  5BPA A;  1QUA A;  4JIJ A;  3DWB A;  2OW0 A;  2PJT A;  1R54 A;  4GQL A;  4H49 A;  3OHO A;  3TSK A;  2Y6C A;  2JIH A;  3WV3 A;  3HDA P;  5B5O A;  3K7N A;  2USN A;  2MLS A;  3L0T A;  3KEK A;  3USN A;  1UTT A;  1ZXC A;  3BA0 A;  5D1U A;  4A7B A;  3LQ0 A;  1G05 A;  4G9L A;  4I03 A;  4FXQ A;  1Q3A A;  1YCM A;  2MZE A;  4FVL A;  1SMP A;  2A8H A;  1UMS A;  1AKL A;  1XFW A;  4DPE A;  2YUF A;  4H76 A;  1J7N A;  1D7X A;  2DW1 A;  3DPE A;  1ZTQ A;  4WF6 A;  1GKD A;  1GO8 P;  1EAK A;  1XFU A;  2D1O A;  1R1I A;  1C7K A;  5L7F A;  3ZUK A;  1KUI A;  2E3X A;  2O3E A;  3E8R A;  5I43 A;  1HOV A;  1R1J A;  1ZS0 A;  1FM1 A;  5B5P A;  2WOA A;  3G42 A;  4L63 A;  2YB9 A;  3O2X A;  1K7G A;  2AIG P;  3L0V A;  2OW1 A;  2OVZ A;  1AST A;  2W0D A;  2O36 A;  3DNG A;  5LAB A;  4GF1 A;  4PKT A;  3HYG A;  3DTE A;  1JK3 A;  2DDF A;  1IAB A;  830C A;  2QPJ A;  2WO9 A;  4A3W A;  4GWN A;  4PKW A;  1D8F A;  1SLN A;  3P1V A;  4FU4 A;  1PWV A;  2OXZ A;  1UMT A;  1HV5 A;  1Z3J A;  4WKI A;  1CAQ A;  4DD8 A;  3ELM A;  2OVX A;  4JA1 A;  5I12 A;  1DTH A;  2L0R A;  1CXV A;  4L19 A;  1IAE A;  1PWP A;  1K7I A;  3LEA A;  3HDB A;  5JMY A;  1PWQ A;  1XFY A;  4QKZ A;  4IUW A;  1CGE A;  1JIW P;  1Y93 A;  2CKI A;  2FV5 A;  2MZH A;  3OHL A;  4JQG A;  3LJZ A;  3MA2 A;  1GE5 A;  1I76 A;  3KRY A;  3KEC A;  3V96 B;  1CK7 A;  1I73 A;  1CGF A;  4WZV A;  4XCT A;  2J0T A;  1PWW A;  2K9C A;  5BOY A;  1GE6 A;  1BSW A;  4AXQ A;  4DV8 A;  4H1Q A;  3GBO A;  3EDG A;  1BQO A;  3EDZ A;  3VI1 A;  2OY4 A;  2ERQ A;  2DW0 A;  1JAP A;  1JAN A;  3LQB A;  1B8Y A;  1XFV A;  4ZR5 A;  3F16 A;  1A86 A;  3KHI A;  1JJ9 A;  3F15 A;  2HU6 A;  3EHY A;  1OM6 A;  2Z2D A;  1JIZ A;  1OZ9 A;  1CQR A;  1R55 A;  1QIA A;  1KUG A;  1UTZ A;  1KAP P;  4R3V A;  5D3C A;  1USN A;  1K7Q A;  2CLT A;  1MMR A;  3CKI A;  1DMT A;  1IAC A;  5H8X A;  3LE9 A;  5BOT A;  1OM8 A;  1O0Q A;  4GUY A;  3LJT A;  1ROS A;  1H71 P;  1G49 A;  1JKY A;  3F17 A;  3SHI A;  4L6T A;  4EFS A;  1TVI A;  1ZP5 A;  4L7A A;  4ILW D;  3AYU A;  2J83 A;  3Q2G A;  5D7W A;  1G12 A;  4XM7 A;  1Y0V A;  1BQQ M;  1B3D A;  5D1S A;  1HY7 A;  4WK7 A;  2FV9 A;  3AYK A;  3P24 A;  2OY2 A;  1I1I P;  1XUC A;  3WV2 A;  3B92 A;  1BKC I;  5I0L A;  2ERO A;  2JNP A;  3KEJ A;  1ZVX A;  5D1T A;  4DF9 A;  3F18 A;  3EHX A;  3B2Z A;  3HBU P;  1XUR A;  4IN9 A;  1SLM A;  1OMJ A;  2X3A A;  4H82 A;  2W14 A;  3LGP A;  1AF0 A;  4GR8 A;  1FBL A;  1XFZ A;  3DTI A;  2Y6D A;  3G5C A;  1XM5 A;  3DL1 A;  4FXY P;  3KWV C;  1G4K A;  3HB2 P;  3ZVS A;  1YOU A;  3HBV P;  3I7I A;  1IAA A;  3O64 A;  1R1H A;  2X3C A;  3LK8 A;  1A85 A;  2X7M A;  1XUD A;  2KRJ A;  1RM8 A;  4PKU A;  4PKQ A;  1SU3 A;  4WKE A;  1WNI A;  1S4B P;  3F19 A;  3Q2H A;  1BIW A;  1HTD A;  1YQY A;  3HY9 A;  3TVC A;  1QIC A;  3TS4 A;  1UEA A;  3LUM A;  2OI0 A;  3DTK A;  1QJI A;  3LIR A;  2W12 A;  2V4B A;  1C3I A;  1RMZ A;  1CGL A;  4GWM A;  5I4O A;  2W15 A;  1XFX A;  1PWU A;  3KME A;  1YP1 A;  2D1N A;  2RJQ A;  4Q1L A;  2AYK A;  1EB6 A;  2MLR A;  4JPA A;  3B8Z A;  3RTS A;  5I3M A;  1JAO A;  2JT6 A;  4H3X A;  2W13 A;  1C8T A;  1ZXV A;  1OM7 A;  3F1A A;  1GO7 P;  4CTH A;  1QIB A;  1IAD A;  4IJO A;  1GKC A;  2RJP A;  1MMB A;  1MNC A;  3ZXH A;  3LMC A;  3DPF A; 
#chains in the Genus database with same CATH homology
 4GR3 A;  4I35 A;  2XS4 A;  1ATL A;  3EWJ A;  1L6J A;  4HX3 A;  1OO9 A;  2E2D A;  3UVC A;  2ERP A;  966C A;  5I2Z A;  2JSD A;  3I7G A;  4GR0 A;  1MMQ A;  1KUK A;  3NX7 A;  4PKV A;  3LIL A;  1BKC A;  1BZS A;  1Y8J A;  1IAG A;  1HFS A;  2XS3 A;  4AIG A;  4ON1 A;  2DW2 A;  3TT4 A;  1MMP A;  2X3B A;  2I47 A;  3AIG A;  2K2G A;  1BUV M;  3N2U A;  1G9K A;  1GE7 A;  3U1R A;  456C A;  3KMC A;  1KBC A;  3WV1 A;  3DSL A;  1KUF A;  3EDI A;  4H84 A;  1SAT A;  1SRP A;  2OXW A;  4HMA A;  4JP4 A;  3RTT A;  1BUD A;  1OS2 A;  2OW2 A;  1JAQ A;  4J4M A;  5CUH A;  1HFC A;  5D2B A;  2OZR A;  1O0T A;  4H2E A;  1JH1 A;  3LKA A;  3EDH A;  5L79 A;  1BM6 A;  4AUO A;  1D8M A;  2YIG A;  1AYK A;  1EUB A;  1CIZ A;  2WO8 A;  4XBH A;  3LJG A;  5CZM A;  4PKS A;  5CXA A;  1KUH A;  3LIK A;  1D5J A;  2SRT A;  3K7L A;  4G0D A;  2DDY A;  1FLS A;  4H30 A;  4AYK A;  3VTG A;  4XM6 A;  2POJ A;  2N8R A;  3LUN A;  4PKR A;  2MZI A;  4XM8 A;  2JT5 A;  2OXU A;  1QJJ A;  2OW9 A;  3HY7 A;  1OS9 A;  3N2V A;  2TCL A;  1GXD A;  1BKC E;  1ND1 A;  5BPA A;  1QUA A;  4JIJ A;  3DWB A;  2OW0 A;  2PJT A;  1R54 A;  4GQL A;  4H49 A;  3OHO A;  3TSK A;  2Y6C A;  2JIH A;  3WV3 A;  3HDA P;  5B5O A;  3K7N A;  2USN A;  2MLS A;  3L0T A;  3KEK A;  3USN A;  1UTT A;  1ZXC A;  3BA0 A;  5D1U A;  4A7B A;  3LQ0 A;  1G05 A;  4G9L A;  4I03 A;  4FXQ A;  1Q3A A;  1YCM A;  2MZE A;  4FVL A;  1SMP A;  2A8H A;  1UMS A;  1AKL A;  1XFW A;  4DPE A;  2YUF A;  4H76 A;  1J7N A;  1D7X A;  2DW1 A;  3DPE A;  1ZTQ A;  4WF6 A;  1GKD A;  1GO8 P;  1EAK A;  1XFU A;  2D1O A;  1R1I A;  1C7K A;  5L7F A;  3ZUK A;  1KUI A;  2E3X A;  2O3E A;  3E8R A;  5I43 A;  1HOV A;  1R1J A;  1ZS0 A;  1FM1 A;  5B5P A;  2WOA A;  3G42 A;  4L63 A;  2YB9 A;  3O2X A;  1K7G A;  2AIG P;  3L0V A;  2OW1 A;  2OVZ A;  1AST A;  2W0D A;  2O36 A;  3DNG A;  5LAB A;  4GF1 A;  4PKT A;  3HYG A;  3DTE A;  1JK3 A;  2DDF A;  1IAB A;  830C A;  2QPJ A;  2WO9 A;  4A3W A;  4GWN A;  4PKW A;  1D8F A;  1SLN A;  3P1V A;  4FU4 A;  1PWV A;  2OXZ A;  1UMT A;  1HV5 A;  1Z3J A;  4WKI A;  1CAQ A;  4DD8 A;  3ELM A;  2OVX A;  4JA1 A;  5I12 A;  1DTH A;  2L0R A;  1CXV A;  4L19 A;  1IAE A;  1PWP A;  1K7I A;  3LEA A;  3HDB A;  5JMY A;  1PWQ A;  1XFY A;  4QKZ A;  4IUW A;  1CGE A;  1JIW P;  1Y93 A;  2CKI A;  2FV5 A;  2MZH A;  3OHL A;  4JQG A;  3LJZ A;  3MA2 A;  1GE5 A;  1I76 A;  3KRY A;  3KEC A;  3V96 B;  1CK7 A;  1I73 A;  1CGF A;  4WZV A;  4XCT A;  2J0T A;  1PWW A;  2K9C A;  5BOY A;  1GE6 A;  1BSW A;  4AXQ A;  4DV8 A;  4H1Q A;  3GBO A;  3EDG A;  1BQO A;  3EDZ A;  3VI1 A;  2OY4 A;  2ERQ A;  2DW0 A;  1JAP A;  1JAN A;  3LQB A;  1B8Y A;  1XFV A;  4ZR5 A;  3F16 A;  1A86 A;  3KHI A;  1JJ9 A;  3F15 A;  2HU6 A;  3EHY A;  1OM6 A;  2Z2D A;  1JIZ A;  1CQR A;  1R55 A;  1QIA A;  1KUG A;  1UTZ A;  1KAP P;  4R3V A;  5D3C A;  1USN A;  1K7Q A;  2CLT A;  1MMR A;  3CKI A;  1DMT A;  1IAC A;  5H8X A;  3LE9 A;  5BOT A;  1OM8 A;  1O0Q A;  4GUY A;  3LJT A;  1ROS A;  1H71 P;  1G49 A;  1JKY A;  3F17 A;  3SHI A;  4L6T A;  4EFS A;  1ZP5 A;  4L7A A;  4ILW D;  3AYU A;  2J83 A;  3Q2G A;  5D7W A;  1G12 A;  4XM7 A;  1Y0V A;  1BQQ M;  1B3D A;  5D1S A;  1HY7 A;  4WK7 A;  2FV9 A;  3AYK A;  3P24 A;  2OY2 A;  1I1I P;  1XUC A;  3WV2 A;  3B92 A;  1BKC I;  5I0L A;  2ERO A;  2JNP A;  3KEJ A;  1ZVX A;  5D1T A;  4DF9 A;  3F18 A;  3EHX A;  3B2Z A;  3HBU P;  1XUR A;  4IN9 A;  1SLM A;  1OMJ A;  2X3A A;  4H82 A;  2W14 A;  3LGP A;  1AF0 A;  4GR8 A;  1FBL A;  1XFZ A;  3DTI A;  2Y6D A;  3G5C A;  3DL1 A;  4FXY P;  3KWV C;  1G4K A;  3HB2 P;  3ZVS A;  1YOU A;  3HBV P;  3I7I A;  1IAA A;  3O64 A;  1R1H A;  2X3C A;  3LK8 A;  1A85 A;  2X7M A;  1XUD A;  2KRJ A;  1RM8 A;  4PKU A;  4PKQ A;  1SU3 A;  4WKE A;  1WNI A;  1S4B P;  3F19 A;  3Q2H A;  1BIW A;  1HTD A;  1YQY A;  3HY9 A;  3TVC A;  1QIC A;  3TS4 A;  1UEA A;  3LUM A;  2OI0 A;  3DTK A;  1QJI A;  3LIR A;  2W12 A;  2V4B A;  1C3I A;  1RMZ A;  1CGL A;  4GWM A;  5I4O A;  2W15 A;  1XFX A;  1PWU A;  3KME A;  1YP1 A;  2D1N A;  2RJQ A;  4Q1L A;  2AYK A;  1EB6 A;  2MLR A;  4JPA A;  3B8Z A;  3RTS A;  5I3M A;  1JAO A;  2JT6 A;  4H3X A;  2W13 A;  1C8T A;  1ZXV A;  1OM7 A;  3F1A A;  1GO7 P;  4CTH A;  1QIB A;  1IAD A;  4IJO A;  1GKC A;  2RJP A;  1MMB A;  1MNC A;  3ZXH A;  3LMC A;  3DPF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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