3L0TA

Crystal structure of catalytic domain of tace with hydantoin inhibitor
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
257
structure length
254
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery and SAR of hydantoin TACE inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Disintegrin and metalloproteinase domain-containing protein
total genus 81
structure length 254
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3l0tA00
1G12A 1BZSA 3EWJA 1BUVM 2W15A 1KUHA 2O3EA 830CA 1Y8JA 3O2XA 1G9KA 4DV8A 1HV5A 3F1AA 3LIRA 3LJTA 1GKDA 2E2DA 1ZTQA 1DTHA 1OMJA 1ASTA 3HY7A 2HU6A 1PWUA 4WK7A 1H71P 4EFSA 2W14A 3TSKA 3TT4A 2TCLA 1IABA 3Q2HA 1KUFA 3LUNA 3WV3A 2W0DA 4DD8A 4DF9A 1IACA 4GR8A 3K7NA 1ZS0A 3KEKA 1RMZA 1XFZA 1BSWA 3V96B 3DWBA 1EUBA 1C7KA 1G05A 1OS2A 1IAGA 1QIAA 3ZVSA 2OXWA 1USNA 5BOTA 1DMTA 1QICA 3LUMA 5LABA 1BQOA 4XBHA 1A85A 2CKIA 2OXUA 3B8ZA 5B5OA 5I43A 3UVCA 3Q2GA 1BKCE 1ATLA 1B3DA 3N2UA 2Y6CA 4IJOA 1C8TA 1KUGA 3EDIA 4AUOA 1CGFA 3ZUKA 1K7QA 3LQ0A 1JIWP 3LKAA 1G4KA 1RM8A 4H76A 5CXAA 1CIZA 1Y0VA 4JP4A 1OS9A 1MMRA 1YOUA 4H84A 1BKCA 3HY9A 2KRJA 1SLNA 2RJPA 1JAOA 2ERPA 3CKIA 1MMPA 1Q3AA 4XM7A 2MZEA 2OW9A 2WOAA 3MA2A 3HBUP 5CZMA 2MZHA 4R3VA 1JIZA 3BA0A 4FVLA 1SU3A 1OM7A 2SRTA 3KWVC 2OY2A 1CGLA 2DDYA 1ZVXA 1CGEA 1K7IA 4G9LA 2QPJA 3DPFA 4WZVA 3RTTA 1BUDA 1SLMA 1BQQM 1YP1A 3VTGA 1JK3A 1R55A 966CA 1CXVA 3TVCA 4JPAA 1I73A 2OXZA 3DL1A 2OVXA 1HY7A 2D1NA 2OZRA 3HDBA 5D7WA 3G5CA 3OHOA 4AYKA 1KAPP 4WKIA 3I7IA 1GE7A 1R1IA 1UEAA 4GWMA 2XS4A 3HBVP 2DW1A 2L0RA 1KUIA 2OY4A 456CA 5CUHA 1B8YA 3KHIA 1QUAA 3HYGA 2USNA 4PKQA 2JT6A 4WF6A 1UMTA 1R1HA 3G42A 1GO7P 1GE5A 1JANA 2I47A 1FBLA 3NX7A 4L6TA 4H1QA 1BIWA 2V4BA 4XCTA 5JMYA 4H30A 3ELMA 2K2GA 3F15A 3I7GA 1A86A 1XFYA 1ZXCA 2POJA 3F19A 2K9CA 3DSLA 2JSDA 2X3BA 3WV1A 2OW1A 1CQRA 2N8RA 3KMEA 1ZP5A 1MNCA 2X3CA 3KECA 1C3IA 1IAAA 4ON1A 2JT5A 3DPEA 1MMQA 1ZXVA 2O36A 3AYUA 3LILA 3KRYA 3LJGA 1L6JA 4JA1A 1SRPA 2W12A 2JNPA 2JIHA 1GO8P 2J83A 2FV9A 3LJZA 1GXDA 1HFSA 4QKZA 3RTSA 4FU4A 1KBCA 1QIBA 1UMSA 5I12A 1JKYA 1G49A 3L0VA 4I03A 1YQYA 3LQBA 2DW0A 1PWVA 1XURA 2EROA 1XUCA 1Y93A 1Z3JA 4HMAA 1XFXA 4PKWA 1QJIA 2XS3A 3F17A 2ERQA 4FXYP 3K7LA 1JAQA 1GKCA 2E3XA 3LMCA 4AXQA 3OHLA 1D7XA 1SATA 1EB6A 3B92A 4GUYA 2MLSA 2CLTA 3P24A 5D1SA 4CTHA 5L79A 1BM6A 4GWNA 4L19A 5I4OA 4JQGA 1HFCA 5D1TA 5BPAA 1CAQA 1CK7A 4PKSA 5D3CA 4ILWD 1OM8A 1ROSA 1AKLA 1D8FA 4L63A 5B5PA 4J4MA 2X7MA 3F16A 1IADA 2YB9A 3VI1A 1FM1A 2Z2DA 2A8HA 3HDAP 3AYKA 5I3MA 4ZR5A 1AYKA 3LEAA 4WKEA 4H82A 2DDFA 2YIGA 3EDHA 3F18A 1O0TA 4H49A 1XFUA 4PKVA 5L7FA 2OVZA 3EHYA 4IN9A 1D8MA 2FV5A 1QJJA 2PJTA 1ND1A 1D5JA 3DNGA 1OM6A 4FXQA 4HX3A 5I2ZA 3LIKA 4XM8A 4A3WA 5H8XA 2WO9A 2DW2A 1UTZA 1I76A 1WNIA 4AIGA 3KMCA 2OW0A 4XM6A 1R54A 2WO8A 2Y6DA 4G0DA 1S4BP 1PWQA 3LE9A 4GF1A 3LK8A 2W13A 1UTTA 4JIJA 5D2BA 3LGPA 3B2ZA 1FLSA 3AIGA 3N2VA 4GQLA 4IUWA 5BOYA 1BKCI 1R1JA 4Q1LA 4GR0A 1K7GA 1HOVA 4PKTA 1KUKA 3GBOA 1OO9A 1IAEA 1JAPA 2RJQA 4H2EA 3P1VA 3HB2P 4DPEA 1MMBA 4PKRA 3TS4A 1O0QA 1XFWA 3EDZA 2OW2A 3EHXA 1AF0A 1YCMA 4I35A 3O64A 3KEJA 2OI0A 1I1IP 3SHIA 3E8RA 1GE6A 4A7BA 5D1UA 3ZXHA 1EAKA 1XFVA 1JJ9A 1J7NA 4PKUA 1XUDA 4GR3A 3U1RA 2MLRA 1JH1A 5I0LA 1SMPA 2AIGP 2MZIA 1HTDA 2AYKA 3USNA 3L0TA 3WV2A 1PWWA 2D1OA 4H3XA 2X3AA 3EDGA 1PWPA 2J0TA
chains in the Genus database with same CATH superfamily
1G12A 1BZSA 3EWJA 1BUVM 2W15A 1KUHA 2O3EA 830CA 1Y8JA 3O2XA 1G9KA 4DV8A 1HV5A 3F1AA 3LIRA 3LJTA 1GKDA 2E2DA 1ZTQA 1DTHA 1OMJA 1ASTA 3DTIA 3HY7A 2HU6A 1PWUA 4WK7A 1H71P 4EFSA 2W14A 3TSKA 3TT4A 2TCLA 1IABA 3Q2HA 1KUFA 3LUNA 3WV3A 2W0DA 4DD8A 4DF9A 1IACA 4GR8A 3K7NA 1ZS0A 3KEKA 1RMZA 1XFZA 1BSWA 3V96B 3DWBA 1EUBA 1C7KA 1G05A 1OS2A 1IAGA 1QIAA 3ZVSA 2OXWA 1USNA 5BOTA 1DMTA 1QICA 3LUMA 5LABA 1BQOA 4XBHA 1A85A 2CKIA 2OXUA 3B8ZA 5B5OA 5I43A 3UVCA 3Q2GA 1BKCE 1ATLA 1B3DA 3N2UA 2Y6CA 4IJOA 1C8TA 1KUGA 3EDIA 4AUOA 1CGFA 2YUFA 3ZUKA 1K7QA 3LQ0A 1JIWP 3LKAA 1G4KA 1RM8A 4H76A 5CXAA 1CIZA 1Y0VA 4JP4A 1OS9A 1MMRA 1YOUA 4H84A 1BKCA 3HY9A 2KRJA 1SLNA 2RJPA 1JAOA 2ERPA 3CKIA 1MMPA 1Q3AA 4XM7A 2MZEA 2OW9A 2WOAA 3MA2A 3HBUP 5CZMA 2MZHA 4R3VA 1JIZA 3BA0A 4FVLA 1SU3A 1OM7A 2SRTA 3KWVC 2OY2A 1CGLA 2DDYA 1ZVXA 1CGEA 1K7IA 4G9LA 2QPJA 3DPFA 4WZVA 3RTTA 1BUDA 1SLMA 1BQQM 1YP1A 3VTGA 1JK3A 1R55A 966CA 1CXVA 3TVCA 4JPAA 1I73A 2OXZA 3DL1A 2OVXA 1HY7A 2D1NA 2OZRA 3HDBA 5D7WA 3G5CA 3OHOA 4AYKA 1KAPP 4WKIA 3I7IA 1GE7A 1R1IA 1UEAA 4GWMA 2XS4A 3HBVP 2DW1A 2L0RA 1KUIA 2OY4A 456CA 5CUHA 1B8YA 3KHIA 1QUAA 3HYGA 2USNA 4PKQA 2JT6A 4WF6A 1UMTA 1R1HA 3G42A 1GO7P 1GE5A 1JANA 2I47A 1FBLA 3NX7A 4L6TA 4H1QA 1BIWA 2V4BA 4XCTA 5JMYA 4H30A 3ELMA 2K2GA 3F15A 3I7GA 1A86A 1XFYA 1ZXCA 2POJA 1XAXA 3F19A 2K9CA 3DSLA 2JSDA 2X3BA 3WV1A 2OW1A 1CQRA 2N8RA 3KMEA 1ZP5A 1MNCA 2X3CA 1XM5A 3KECA 1C3IA 1IAAA 4ON1A 2JT5A 3DPEA 1MMQA 1ZXVA 2O36A 3AYUA 3LILA 3KRYA 3LJGA 1L6JA 4JA1A 1SRPA 2W12A 2JNPA 2JIHA 1GO8P 2J83A 2FV9A 3LJZA 1GXDA 1HFSA 4QKZA 3RTSA 4FU4A 1KBCA 1QIBA 1UMSA 5I12A 1JKYA 1G49A 3L0VA 4I03A 1YQYA 3LQBA 2DW0A 1PWVA 1XURA 2EROA 1XUCA 1Y93A 1Z3JA 4HMAA 1XFXA 4PKWA 1QJIA 2XS3A 3F17A 2ERQA 4FXYP 3K7LA 1JAQA 1GKCA 2E3XA 3LMCA 4AXQA 3OHLA 1D7XA 1SATA 1EB6A 3B92A 4GUYA 2MLSA 2CLTA 3P24A 5D1SA 4CTHA 5L79A 1BM6A 4GWNA 4L19A 5I4OA 4JQGA 1HFCA 5D1TA 4L7AA 5BPAA 1CAQA 1CK7A 4PKSA 5D3CA 4ILWD 1OM8A 1ROSA 1AKLA 1D8FA 4L63A 5B5PA 4J4MA 2X7MA 3F16A 1IADA 2YB9A 3VI1A 1FM1A 2Z2DA 2A8HA 3HDAP 3AYKA 5I3MA 4ZR5A 1AYKA 3LEAA 4WKEA 4H82A 3DTEA 2DDFA 3DTKA 2YIGA 3EDHA 3F18A 1O0TA 4H49A 1XFUA 4PKVA 5L7FA 2OVZA 3EHYA 4IN9A 1D8MA 2FV5A 1QJJA 2PJTA 1ND1A 1D5JA 3DNGA 1OM6A 4FXQA 4HX3A 5I2ZA 3LIKA 4XM8A 4A3WA 5H8XA 2WO9A 2DW2A 1UTZA 1I76A 1WNIA 4AIGA 3KMCA 2OW0A 4XM6A 1R54A 2WO8A 2Y6DA 4G0DA 1S4BP 1PWQA 3LE9A 4GF1A 3LK8A 2W13A 1UTTA 4JIJA 5D2BA 3LGPA 3B2ZA 1FLSA 3AIGA 3N2VA 4GQLA 1OZ9A 4IUWA 5BOYA 1BKCI 1R1JA 4Q1LA 4GR0A 1K7GA 1HOVA 4PKTA 1KUKA 3GBOA 1OO9A 1IAEA 1JAPA 2RJQA 4H2EA 3P1VA 3HB2P 4DPEA 1MMBA 4PKRA 3TS4A 1O0QA 1XFWA 3EDZA 2OW2A 3EHXA 1AF0A 1YCMA 4I35A 3O64A 3KEJA 2OI0A 1I1IP 3SHIA 3E8RA 1GE6A 4A7BA 5D1UA 3ZXHA 1EAKA 1XFVA 1JJ9A 1J7NA 4PKUA 1XUDA 4GR3A 3U1RA 2MLRA 1TVIA 1JH1A 5I0LA 1SMPA 2AIGP 2MZIA 1HTDA 2AYKA 3USNA 3L0TA 3WV2A 1PWWA 2D1OA 4H3XA 2X3AA 3EDGA 1PWPA 2J0TA
chains in the Genus database with same CATH topology
1G12A 1BZSA 3EWJA 1BUVM 2W15A 1KUHA 2O3EA 830CA 1Y8JA 3O2XA 1G9KA 4DV8A 1HV5A 3F1AA 3LIRA 3LJTA 1GKDA 2E2DA 1ZTQA 1DTHA 1OMJA 1ASTA 3DTIA 3HY7A 2HU6A 1PWUA 4WK7A 1H71P 4EFSA 2W14A 3TSKA 3TT4A 2TCLA 1IABA 3Q2HA 1KUFA 3LUNA 3WV3A 2W0DA 4DD8A 4DF9A 1IACA 4GR8A 3K7NA 1ZS0A 3KEKA 1RMZA 1XFZA 1BSWA 3V96B 3DWBA 1EUBA 1C7KA 1G05A 1OS2A 1IAGA 1QIAA 3ZVSA 2OXWA 1USNA 5BOTA 1DMTA 1QICA 3LUMA 5LABA 1BQOA 4XBHA 1A85A 2CKIA 2OXUA 3B8ZA 5B5OA 5I43A 3UVCA 3Q2GA 1BKCE 1ATLA 1B3DA 3N2UA 2Y6CA 4IJOA 1C8TA 1KUGA 3EDIA 4AUOA 1CGFA 2YUFA 3ZUKA 1K7QA 3LQ0A 1JIWP 3LKAA 1G4KA 1RM8A 4H76A 5CXAA 1CIZA 1Y0VA 4JP4A 1OS9A 1MMRA 1YOUA 4H84A 1BKCA 3HY9A 2KRJA 1SLNA 2RJPA 1JAOA 2ERPA 3CKIA 1MMPA 1Q3AA 4XM7A 2MZEA 2OW9A 2WOAA 3MA2A 3HBUP 5CZMA 2MZHA 4R3VA 1JIZA 3BA0A 4FVLA 1SU3A 1OM7A 2SRTA 3KWVC 2OY2A 1CGLA 2DDYA 1ZVXA 1CGEA 1K7IA 4G9LA 2QPJA 3DPFA 4WZVA 3RTTA 1BUDA 1SLMA 1BQQM 1YP1A 3VTGA 1JK3A 1R55A 966CA 1CXVA 3TVCA 4JPAA 1I73A 2OXZA 3DL1A 2OVXA 1HY7A 2D1NA 2OZRA 3HDBA 5D7WA 3G5CA 3OHOA 4AYKA 1KAPP 4WKIA 3I7IA 1GE7A 1R1IA 1UEAA 4GWMA 2XS4A 3HBVP 2DW1A 2L0RA 1KUIA 2OY4A 456CA 5CUHA 1B8YA 3KHIA 1QUAA 3HYGA 2USNA 4PKQA 2JT6A 4WF6A 1UMTA 1R1HA 3G42A 1GO7P 1GE5A 1JANA 2I47A 1FBLA 3NX7A 4L6TA 4H1QA 1BIWA 2V4BA 4XCTA 5JMYA 4H30A 3ELMA 2K2GA 3F15A 3I7GA 1A86A 1XFYA 1ZXCA 2POJA 3F19A 2K9CA 3DSLA 2JSDA 2X3BA 3WV1A 2OW1A 1CQRA 2N8RA 3KMEA 1ZP5A 1MNCA 2X3CA 3KECA 1C3IA 1IAAA 4ON1A 2JT5A 3DPEA 1MMQA 1ZXVA 2O36A 3AYUA 3LILA 3KRYA 3LJGA 1L6JA 4JA1A 1SRPA 2W12A 2JNPA 2JIHA 1GO8P 2J83A 2FV9A 3LJZA 1GXDA 1HFSA 4QKZA 3RTSA 4FU4A 1KBCA 1QIBA 1UMSA 5I12A 1JKYA 1G49A 3L0VA 4I03A 1YQYA 3LQBA 2DW0A 1PWVA 1XURA 2EROA 1XUCA 1Y93A 1Z3JA 4HMAA 1XFXA 4PKWA 1QJIA 2XS3A 3F17A 2ERQA 4FXYP 3K7LA 1JAQA 1GKCA 2E3XA 3LMCA 4AXQA 3OHLA 1D7XA 1SATA 1EB6A 3B92A 4GUYA 2MLSA 2CLTA 3P24A 5D1SA 4CTHA 5L79A 1BM6A 4GWNA 4L19A 5I4OA 4JQGA 1HFCA 5D1TA 4L7AA 5BPAA 1CAQA 1CK7A 4PKSA 5D3CA 4ILWD 1OM8A 1ROSA 1AKLA 1D8FA 4L63A 5B5PA 4J4MA 2X7MA 3F16A 1IADA 2YB9A 3VI1A 1FM1A 2Z2DA 2A8HA 3HDAP 3AYKA 5I3MA 4ZR5A 1AYKA 3LEAA 4WKEA 4H82A 3DTEA 2DDFA 3DTKA 2YIGA 3EDHA 3F18A 1O0TA 4H49A 1XFUA 4PKVA 5L7FA 2OVZA 3EHYA 4IN9A 1D8MA 2FV5A 1QJJA 2PJTA 1ND1A 1D5JA 3DNGA 1OM6A 4FXQA 4HX3A 5I2ZA 3LIKA 4XM8A 4A3WA 5H8XA 2WO9A 2DW2A 1UTZA 1I76A 1WNIA 4AIGA 3KMCA 2OW0A 4XM6A 1R54A 2WO8A 2Y6DA 4G0DA 1S4BP 1PWQA 3LE9A 4GF1A 3LK8A 2W13A 1UTTA 4JIJA 5D2BA 3LGPA 3B2ZA 1FLSA 3AIGA 3N2VA 4GQLA 4IUWA 5BOYA 1BKCI 1R1JA 4Q1LA 4GR0A 1K7GA 1HOVA 4PKTA 1KUKA 3GBOA 1OO9A 1IAEA 1JAPA 2RJQA 4H2EA 3P1VA 3HB2P 4DPEA 1MMBA 4PKRA 3TS4A 1O0QA 1XFWA 3EDZA 2OW2A 3EHXA 1AF0A 1YCMA 4I35A 3O64A 3KEJA 2OI0A 1I1IP 3SHIA 3E8RA 1GE6A 4A7BA 5D1UA 3ZXHA 1EAKA 1XFVA 1JJ9A 1J7NA 4PKUA 1XUDA 4GR3A 3U1RA 2MLRA 1JH1A 5I0LA 1SMPA 2AIGP 2MZIA 1HTDA 2AYKA 3USNA 3L0TA 3WV2A 1PWWA 2D1OA 4H3XA 2X3AA 3EDGA 1PWPA 2J0TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1G12 A;  1BZS A;  3EWJ A;  1BUV M;  2W15 A;  1KUH A;  2O3E A;  830C A;  1Y8J A;  3O2X A;  1G9K A;  4DV8 A;  1HV5 A;  3F1A A;  3LIR A;  3LJT A;  1GKD A;  2E2D A;  1ZTQ A;  1DTH A;  1OMJ A;  1AST A;  3HY7 A;  2HU6 A;  1PWU A;  4WK7 A;  1H71 P;  4EFS A;  2W14 A;  3TSK A;  3TT4 A;  2TCL A;  1IAB A;  3Q2H A;  1KUF A;  3LUN A;  3WV3 A;  2W0D A;  4DD8 A;  4DF9 A;  1IAC A;  4GR8 A;  3K7N A;  1ZS0 A;  3KEK A;  1RMZ A;  1XFZ A;  1BSW A;  3V96 B;  3DWB A;  1EUB A;  1C7K A;  1G05 A;  1OS2 A;  1IAG A;  1QIA A;  3ZVS A;  2OXW A;  1USN A;  5BOT A;  1DMT A;  1QIC A;  3LUM A;  5LAB A;  1BQO A;  4XBH A;  1A85 A;  2CKI A;  2OXU A;  3B8Z A;  5B5O A;  5I43 A;  3UVC A;  3Q2G A;  1BKC E;  1ATL A;  1B3D A;  3N2U A;  2Y6C A;  4IJO A;  1C8T A;  1KUG A;  3EDI A;  4AUO A;  1CGF A;  3ZUK A;  1K7Q A;  3LQ0 A;  1JIW P;  3LKA A;  1G4K A;  1RM8 A;  4H76 A;  5CXA A;  1CIZ A;  1Y0V A;  4JP4 A;  1OS9 A;  1MMR A;  1YOU A;  4H84 A;  1BKC A;  3HY9 A;  2KRJ A;  1SLN A;  2RJP A;  1JAO A;  2ERP A;  3CKI A;  1MMP A;  1Q3A A;  4XM7 A;  2MZE A;  2OW9 A;  2WOA A;  3MA2 A;  3HBU P;  5CZM A;  2MZH A;  4R3V A;  1JIZ A;  3BA0 A;  4FVL A;  1SU3 A;  1OM7 A;  2SRT A;  3KWV C;  2OY2 A;  1CGL A;  2DDY A;  1ZVX A;  1CGE A;  1K7I A;  4G9L A;  2QPJ A;  3DPF A;  4WZV A;  3RTT A;  1BUD A;  1SLM A;  1BQQ M;  1YP1 A;  3VTG A;  1JK3 A;  1R55 A;  966C A;  1CXV A;  3TVC A;  4JPA A;  1I73 A;  2OXZ A;  3DL1 A;  2OVX A;  1HY7 A;  2D1N A;  2OZR A;  3HDB A;  5D7W A;  3G5C A;  3OHO A;  4AYK A;  1KAP P;  4WKI A;  3I7I A;  1GE7 A;  1R1I A;  1UEA A;  4GWM A;  2XS4 A;  3HBV P;  2DW1 A;  2L0R A;  1KUI A;  2OY4 A;  456C A;  5CUH A;  1B8Y A;  3KHI A;  1QUA A;  3HYG A;  2USN A;  4PKQ A;  2JT6 A;  4WF6 A;  1UMT A;  1R1H A;  3G42 A;  1GO7 P;  1GE5 A;  1JAN A;  2I47 A;  1FBL A;  3NX7 A;  4L6T A;  4H1Q A;  1BIW A;  2V4B A;  4XCT A;  5JMY A;  4H30 A;  3ELM A;  2K2G A;  3F15 A;  3I7G A;  1A86 A;  1XFY A;  1ZXC A;  2POJ A;  3F19 A;  2K9C A;  3DSL A;  2JSD A;  2X3B A;  3WV1 A;  2OW1 A;  1CQR A;  2N8R A;  3KME A;  1ZP5 A;  1MNC A;  2X3C A;  3KEC A;  1C3I A;  1IAA A;  4ON1 A;  2JT5 A;  3DPE A;  1MMQ A;  1ZXV A;  2O36 A;  3AYU A;  3LIL A;  3KRY A;  3LJG A;  1L6J A;  4JA1 A;  1SRP A;  2W12 A;  2JNP A;  2JIH A;  1GO8 P;  2J83 A;  2FV9 A;  3LJZ A;  1GXD A;  1HFS A;  4QKZ A;  3RTS A;  4FU4 A;  1KBC A;  1QIB A;  1UMS A;  5I12 A;  1JKY A;  1G49 A;  3L0V A;  4I03 A;  1YQY A;  3LQB A;  2DW0 A;  1PWV A;  1XUR A;  2ERO A;  1XUC A;  1Y93 A;  1Z3J A;  4HMA A;  1XFX A;  4PKW A;  1QJI A;  2XS3 A;  3F17 A;  2ERQ A;  4FXY P;  3K7L A;  1JAQ A;  1GKC A;  2E3X A;  3LMC A;  4AXQ A;  3OHL A;  1D7X A;  1SAT A;  1EB6 A;  3B92 A;  4GUY A;  2MLS A;  2CLT A;  3P24 A;  5D1S A;  4CTH A;  5L79 A;  1BM6 A;  4GWN A;  4L19 A;  5I4O A;  4JQG A;  1HFC A;  5D1T A;  5BPA A;  1CAQ A;  1CK7 A;  4PKS A;  5D3C A;  4ILW D;  1OM8 A;  1ROS A;  1AKL A;  1D8F A;  4L63 A;  5B5P A;  4J4M A;  2X7M A;  3F16 A;  1IAD A;  2YB9 A;  3VI1 A;  1FM1 A;  2Z2D A;  2A8H A;  3HDA P;  3AYK A;  5I3M A;  4ZR5 A;  1AYK A;  3LEA A;  4WKE A;  4H82 A;  2DDF A;  2YIG A;  3EDH A;  3F18 A;  1O0T A;  4H49 A;  1XFU A;  4PKV A;  5L7F A;  2OVZ A;  3EHY A;  4IN9 A;  1D8M A;  2FV5 A;  1QJJ A;  2PJT A;  1ND1 A;  1D5J A;  3DNG A;  1OM6 A;  4FXQ A;  4HX3 A;  5I2Z A;  3LIK A;  4XM8 A;  4A3W A;  5H8X A;  2WO9 A;  2DW2 A;  1UTZ A;  1I76 A;  1WNI A;  4AIG A;  3KMC A;  2OW0 A;  4XM6 A;  1R54 A;  2WO8 A;  2Y6D A;  4G0D A;  1S4B P;  1PWQ A;  3LE9 A;  4GF1 A;  3LK8 A;  2W13 A;  1UTT A;  4JIJ A;  5D2B A;  3LGP A;  3B2Z A;  1FLS A;  3AIG A;  3N2V A;  4GQL A;  4IUW A;  5BOY A;  1BKC I;  1R1J A;  4Q1L A;  4GR0 A;  1K7G A;  1HOV A;  4PKT A;  1KUK A;  3GBO A;  1OO9 A;  1IAE A;  1JAP A;  2RJQ A;  4H2E A;  3P1V A;  3HB2 P;  4DPE A;  1MMB A;  4PKR A;  3TS4 A;  1O0Q A;  1XFW A;  3EDZ A;  2OW2 A;  3EHX A;  1AF0 A;  1YCM A;  4I35 A;  3O64 A;  3KEJ A;  2OI0 A;  1I1I P;  3SHI A;  3E8R A;  1GE6 A;  4A7B A;  5D1U A;  3ZXH A;  1EAK A;  1XFV A;  1JJ9 A;  1J7N A;  4PKU A;  1XUD A;  4GR3 A;  3U1R A;  2MLR A;  1JH1 A;  5I0L A;  1SMP A;  2AIG P;  2MZI A;  1HTD A;  2AYK A;  3USN A;  3L0T A;  3WV2 A;  1PWW A;  2D1O A;  4H3X A;  2X3A A;  3EDG A;  1PWP A;  2J0T A; 
#chains in the Genus database with same CATH topology
 1G12 A;  1BZS A;  3EWJ A;  1BUV M;  2W15 A;  1KUH A;  2O3E A;  830C A;  1Y8J A;  3O2X A;  1G9K A;  4DV8 A;  1HV5 A;  3F1A A;  3LIR A;  3LJT A;  1GKD A;  2E2D A;  1ZTQ A;  1DTH A;  1OMJ A;  1AST A;  3DTI A;  3HY7 A;  2HU6 A;  1PWU A;  4WK7 A;  1H71 P;  4EFS A;  2W14 A;  3TSK A;  3TT4 A;  2TCL A;  1IAB A;  3Q2H A;  1KUF A;  3LUN A;  3WV3 A;  2W0D A;  4DD8 A;  4DF9 A;  1IAC A;  4GR8 A;  3K7N A;  1ZS0 A;  3KEK A;  1RMZ A;  1XFZ A;  1BSW A;  3V96 B;  3DWB A;  1EUB A;  1C7K A;  1G05 A;  1OS2 A;  1IAG A;  1QIA A;  3ZVS A;  2OXW A;  1USN A;  5BOT A;  1DMT A;  1QIC A;  3LUM A;  5LAB A;  1BQO A;  4XBH A;  1A85 A;  2CKI A;  2OXU A;  3B8Z A;  5B5O A;  5I43 A;  3UVC A;  3Q2G A;  1BKC E;  1ATL A;  1B3D A;  3N2U A;  2Y6C A;  4IJO A;  1C8T A;  1KUG A;  3EDI A;  4AUO A;  1CGF A;  2YUF A;  3ZUK A;  1K7Q A;  3LQ0 A;  1JIW P;  3LKA A;  1G4K A;  1RM8 A;  4H76 A;  5CXA A;  1CIZ A;  1Y0V A;  4JP4 A;  1OS9 A;  1MMR A;  1YOU A;  4H84 A;  1BKC A;  3HY9 A;  2KRJ A;  1SLN A;  2RJP A;  1JAO A;  2ERP A;  3CKI A;  1MMP A;  1Q3A A;  4XM7 A;  2MZE A;  2OW9 A;  2WOA A;  3MA2 A;  3HBU P;  5CZM A;  2MZH A;  4R3V A;  1JIZ A;  3BA0 A;  4FVL A;  1SU3 A;  1OM7 A;  2SRT A;  3KWV C;  2OY2 A;  1CGL A;  2DDY A;  1ZVX A;  1CGE A;  1K7I A;  4G9L A;  2QPJ A;  3DPF A;  4WZV A;  3RTT A;  1BUD A;  1SLM A;  1BQQ M;  1YP1 A;  3VTG A;  1JK3 A;  1R55 A;  966C A;  1CXV A;  3TVC A;  4JPA A;  1I73 A;  2OXZ A;  3DL1 A;  2OVX A;  1HY7 A;  2D1N A;  2OZR A;  3HDB A;  5D7W A;  3G5C A;  3OHO A;  4AYK A;  1KAP P;  4WKI A;  3I7I A;  1GE7 A;  1R1I A;  1UEA A;  4GWM A;  2XS4 A;  3HBV P;  2DW1 A;  2L0R A;  1KUI A;  2OY4 A;  456C A;  5CUH A;  1B8Y A;  3KHI A;  1QUA A;  3HYG A;  2USN A;  4PKQ A;  2JT6 A;  4WF6 A;  1UMT A;  1R1H A;  3G42 A;  1GO7 P;  1GE5 A;  1JAN A;  2I47 A;  1FBL A;  3NX7 A;  4L6T A;  4H1Q A;  1BIW A;  2V4B A;  4XCT A;  5JMY A;  4H30 A;  3ELM A;  2K2G A;  3F15 A;  3I7G A;  1A86 A;  1XFY A;  1ZXC A;  2POJ A;  1XAX A;  3F19 A;  2K9C A;  3DSL A;  2JSD A;  2X3B A;  3WV1 A;  2OW1 A;  1CQR A;  2N8R A;  3KME A;  1ZP5 A;  1MNC A;  2X3C A;  1XM5 A;  3KEC A;  1C3I A;  1IAA A;  4ON1 A;  2JT5 A;  3DPE A;  1MMQ A;  1ZXV A;  2O36 A;  3AYU A;  3LIL A;  3KRY A;  3LJG A;  1L6J A;  4JA1 A;  1SRP A;  2W12 A;  2JNP A;  2JIH A;  1GO8 P;  2J83 A;  2FV9 A;  3LJZ A;  1GXD A;  1HFS A;  4QKZ A;  3RTS A;  4FU4 A;  1KBC A;  1QIB A;  1UMS A;  5I12 A;  1JKY A;  1G49 A;  3L0V A;  4I03 A;  1YQY A;  3LQB A;  2DW0 A;  1PWV A;  1XUR A;  2ERO A;  1XUC A;  1Y93 A;  1Z3J A;  4HMA A;  1XFX A;  4PKW A;  1QJI A;  2XS3 A;  3F17 A;  2ERQ A;  4FXY P;  3K7L A;  1JAQ A;  1GKC A;  2E3X A;  3LMC A;  4AXQ A;  3OHL A;  1D7X A;  1SAT A;  1EB6 A;  3B92 A;  4GUY A;  2MLS A;  2CLT A;  3P24 A;  5D1S A;  4CTH A;  5L79 A;  1BM6 A;  4GWN A;  4L19 A;  5I4O A;  4JQG A;  1HFC A;  5D1T A;  4L7A A;  5BPA A;  1CAQ A;  1CK7 A;  4PKS A;  5D3C A;  4ILW D;  1OM8 A;  1ROS A;  1AKL A;  1D8F A;  4L63 A;  5B5P A;  4J4M A;  2X7M A;  3F16 A;  1IAD A;  2YB9 A;  3VI1 A;  1FM1 A;  2Z2D A;  2A8H A;  3HDA P;  3AYK A;  5I3M A;  4ZR5 A;  1AYK A;  3LEA A;  4WKE A;  4H82 A;  3DTE A;  2DDF A;  3DTK A;  2YIG A;  3EDH A;  3F18 A;  1O0T A;  4H49 A;  1XFU A;  4PKV A;  5L7F A;  2OVZ A;  3EHY A;  4IN9 A;  1D8M A;  2FV5 A;  1QJJ A;  2PJT A;  1ND1 A;  1D5J A;  3DNG A;  1OM6 A;  4FXQ A;  4HX3 A;  5I2Z A;  3LIK A;  4XM8 A;  4A3W A;  5H8X A;  2WO9 A;  2DW2 A;  1UTZ A;  1I76 A;  1WNI A;  4AIG A;  3KMC A;  2OW0 A;  4XM6 A;  1R54 A;  2WO8 A;  2Y6D A;  4G0D A;  1S4B P;  1PWQ A;  3LE9 A;  4GF1 A;  3LK8 A;  2W13 A;  1UTT A;  4JIJ A;  5D2B A;  3LGP A;  3B2Z A;  1FLS A;  3AIG A;  3N2V A;  4GQL A;  1OZ9 A;  4IUW A;  5BOY A;  1BKC I;  1R1J A;  4Q1L A;  4GR0 A;  1K7G A;  1HOV A;  4PKT A;  1KUK A;  3GBO A;  1OO9 A;  1IAE A;  1JAP A;  2RJQ A;  4H2E A;  3P1V A;  3HB2 P;  4DPE A;  1MMB A;  4PKR A;  3TS4 A;  1O0Q A;  1XFW A;  3EDZ A;  2OW2 A;  3EHX A;  1AF0 A;  1YCM A;  4I35 A;  3O64 A;  3KEJ A;  2OI0 A;  1I1I P;  3SHI A;  3E8R A;  1GE6 A;  4A7B A;  5D1U A;  3ZXH A;  1EAK A;  1XFV A;  1JJ9 A;  1J7N A;  4PKU A;  1XUD A;  4GR3 A;  3U1R A;  2MLR A;  1TVI A;  1JH1 A;  5I0L A;  1SMP A;  2AIG P;  2MZI A;  1HTD A;  2AYK A;  3USN A;  3L0T A;  3WV2 A;  1PWW A;  2D1O A;  4H3X A;  2X3A A;  3EDG A;  1PWP A;  2J0T A; 
#chains in the Genus database with same CATH homology
 1G12 A;  1BZS A;  3EWJ A;  1BUV M;  2W15 A;  1KUH A;  2O3E A;  830C A;  1Y8J A;  3O2X A;  1G9K A;  4DV8 A;  1HV5 A;  3F1A A;  3LIR A;  3LJT A;  1GKD A;  2E2D A;  1ZTQ A;  1DTH A;  1OMJ A;  1AST A;  3DTI A;  3HY7 A;  2HU6 A;  1PWU A;  4WK7 A;  1H71 P;  4EFS A;  2W14 A;  3TSK A;  3TT4 A;  2TCL A;  1IAB A;  3Q2H A;  1KUF A;  3LUN A;  3WV3 A;  2W0D A;  4DD8 A;  4DF9 A;  1IAC A;  4GR8 A;  3K7N A;  1ZS0 A;  3KEK A;  1RMZ A;  1XFZ A;  1BSW A;  3V96 B;  3DWB A;  1EUB A;  1C7K A;  1G05 A;  1OS2 A;  1IAG A;  1QIA A;  3ZVS A;  2OXW A;  1USN A;  5BOT A;  1DMT A;  1QIC A;  3LUM A;  5LAB A;  1BQO A;  4XBH A;  1A85 A;  2CKI A;  2OXU A;  3B8Z A;  5B5O A;  5I43 A;  3UVC A;  3Q2G A;  1BKC E;  1ATL A;  1B3D A;  3N2U A;  2Y6C A;  4IJO A;  1C8T A;  1KUG A;  3EDI A;  4AUO A;  1CGF A;  2YUF A;  3ZUK A;  1K7Q A;  3LQ0 A;  1JIW P;  3LKA A;  1G4K A;  1RM8 A;  4H76 A;  5CXA A;  1CIZ A;  1Y0V A;  4JP4 A;  1OS9 A;  1MMR A;  1YOU A;  4H84 A;  1BKC A;  3HY9 A;  2KRJ A;  1SLN A;  2RJP A;  1JAO A;  2ERP A;  3CKI A;  1MMP A;  1Q3A A;  4XM7 A;  2MZE A;  2OW9 A;  2WOA A;  3MA2 A;  3HBU P;  5CZM A;  2MZH A;  4R3V A;  1JIZ A;  3BA0 A;  4FVL A;  1SU3 A;  1OM7 A;  2SRT A;  3KWV C;  2OY2 A;  1CGL A;  2DDY A;  1ZVX A;  1CGE A;  1K7I A;  4G9L A;  2QPJ A;  3DPF A;  4WZV A;  3RTT A;  1BUD A;  1SLM A;  1BQQ M;  1YP1 A;  3VTG A;  1JK3 A;  1R55 A;  966C A;  1CXV A;  3TVC A;  4JPA A;  1I73 A;  2OXZ A;  3DL1 A;  2OVX A;  1HY7 A;  2D1N A;  2OZR A;  3HDB A;  5D7W A;  3G5C A;  3OHO A;  4AYK A;  1KAP P;  4WKI A;  3I7I A;  1GE7 A;  1R1I A;  1UEA A;  4GWM A;  2XS4 A;  3HBV P;  2DW1 A;  2L0R A;  1KUI A;  2OY4 A;  456C A;  5CUH A;  1B8Y A;  3KHI A;  1QUA A;  3HYG A;  2USN A;  4PKQ A;  2JT6 A;  4WF6 A;  1UMT A;  1R1H A;  3G42 A;  1GO7 P;  1GE5 A;  1JAN A;  2I47 A;  1FBL A;  3NX7 A;  4L6T A;  4H1Q A;  1BIW A;  2V4B A;  4XCT A;  5JMY A;  4H30 A;  3ELM A;  2K2G A;  3F15 A;  3I7G A;  1A86 A;  1XFY A;  1ZXC A;  2POJ A;  3F19 A;  2K9C A;  3DSL A;  2JSD A;  2X3B A;  3WV1 A;  2OW1 A;  1CQR A;  2N8R A;  3KME A;  1ZP5 A;  1MNC A;  2X3C A;  3KEC A;  1C3I A;  1IAA A;  4ON1 A;  2JT5 A;  3DPE A;  1MMQ A;  1ZXV A;  2O36 A;  3AYU A;  3LIL A;  3KRY A;  3LJG A;  1L6J A;  4JA1 A;  1SRP A;  2W12 A;  2JNP A;  2JIH A;  1GO8 P;  2J83 A;  2FV9 A;  3LJZ A;  1GXD A;  1HFS A;  4QKZ A;  3RTS A;  4FU4 A;  1KBC A;  1QIB A;  1UMS A;  5I12 A;  1JKY A;  1G49 A;  3L0V A;  4I03 A;  1YQY A;  3LQB A;  2DW0 A;  1PWV A;  1XUR A;  2ERO A;  1XUC A;  1Y93 A;  1Z3J A;  4HMA A;  1XFX A;  4PKW A;  1QJI A;  2XS3 A;  3F17 A;  2ERQ A;  4FXY P;  3K7L A;  1JAQ A;  1GKC A;  2E3X A;  3LMC A;  4AXQ A;  3OHL A;  1D7X A;  1SAT A;  1EB6 A;  3B92 A;  4GUY A;  2MLS A;  2CLT A;  3P24 A;  5D1S A;  4CTH A;  5L79 A;  1BM6 A;  4GWN A;  4L19 A;  5I4O A;  4JQG A;  1HFC A;  5D1T A;  4L7A A;  5BPA A;  1CAQ A;  1CK7 A;  4PKS A;  5D3C A;  4ILW D;  1OM8 A;  1ROS A;  1AKL A;  1D8F A;  4L63 A;  5B5P A;  4J4M A;  2X7M A;  3F16 A;  1IAD A;  2YB9 A;  3VI1 A;  1FM1 A;  2Z2D A;  2A8H A;  3HDA P;  3AYK A;  5I3M A;  4ZR5 A;  1AYK A;  3LEA A;  4WKE A;  4H82 A;  3DTE A;  2DDF A;  3DTK A;  2YIG A;  3EDH A;  3F18 A;  1O0T A;  4H49 A;  1XFU A;  4PKV A;  5L7F A;  2OVZ A;  3EHY A;  4IN9 A;  1D8M A;  2FV5 A;  1QJJ A;  2PJT A;  1ND1 A;  1D5J A;  3DNG A;  1OM6 A;  4FXQ A;  4HX3 A;  5I2Z A;  3LIK A;  4XM8 A;  4A3W A;  5H8X A;  2WO9 A;  2DW2 A;  1UTZ A;  1I76 A;  1WNI A;  4AIG A;  3KMC A;  2OW0 A;  4XM6 A;  1R54 A;  2WO8 A;  2Y6D A;  4G0D A;  1S4B P;  1PWQ A;  3LE9 A;  4GF1 A;  3LK8 A;  2W13 A;  1UTT A;  4JIJ A;  5D2B A;  3LGP A;  3B2Z A;  1FLS A;  3AIG A;  3N2V A;  4GQL A;  4IUW A;  5BOY A;  1BKC I;  1R1J A;  4Q1L A;  4GR0 A;  1K7G A;  1HOV A;  4PKT A;  1KUK A;  3GBO A;  1OO9 A;  1IAE A;  1JAP A;  2RJQ A;  4H2E A;  3P1V A;  3HB2 P;  4DPE A;  1MMB A;  4PKR A;  3TS4 A;  1O0Q A;  1XFW A;  3EDZ A;  2OW2 A;  3EHX A;  1AF0 A;  1YCM A;  4I35 A;  3O64 A;  3KEJ A;  2OI0 A;  1I1I P;  3SHI A;  3E8R A;  1GE6 A;  4A7B A;  5D1U A;  3ZXH A;  1EAK A;  1XFV A;  1JJ9 A;  1J7N A;  4PKU A;  1XUD A;  4GR3 A;  3U1R A;  2MLR A;  1JH1 A;  5I0L A;  1SMP A;  2AIG P;  2MZI A;  1HTD A;  2AYK A;  3USN A;  3L0T A;  3WV2 A;  1PWW A;  2D1O A;  4H3X A;  2X3A A;  3EDG A;  1PWP A;  2J0T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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