3L0TA

Crystal structure of catalytic domain of tace with hydantoin inhibitor
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
257
structure length
254
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Disintegrin and metalloproteinase domain-containing protein
publication title Discovery and SAR of hydantoin TACE inhibitors.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 81
structure length 254
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3l0tA00
1GE5A 1A86A 4ZR5A 5H8XA 1HV5A 3NX7A 2O36A 2Y6DA 1PWQA 3LK8A 3ZVSA 3Q2HA 1XFXA 2D1OA 3G42A 1OMJA 1MMBA 830CA 2OW0A 3EWJA 3VTGA 3LQ0A 4PKQA 3DSLA 4JIJA 1EAKA 2Z2DA 3HY7A 4R3VA 1Y8JA 3E8RA 1SATA 5L79A 5I0LA 1CXVA 3F16A 2X3CA 3DNGA 3KWVC 1AKLA 4I03A 1J7NA 2DW1A 1MMQA 2Y6CA 1SLMA 1K7GA 1XUDA 1SRPA 4XM6A 1BZSA 1FBLA 1EUBA 1QIAA 4AYKA 1D8FA 2DDYA 4HX3A 1R1JA 3UVCA 4AXQA 1S4BP 1CGFA 5I2ZA 1JIZA 3ELMA 1IAEA 2DDFA 1PWUA 3LJGA 4H3XA 1IAGA 2YIGA 1C7KA 456CA 1I76A 4EFSA 4GR0A 1JAOA 5JMYA 1IABA 4DV8A 3HDBA 2WO9A 4PKUA 4DD8A 2MZEA 3F1AA 3RTSA 1XFYA 2X7MA 3AIGA 3B92A 3O2XA 4XBHA 2E2DA 5D1TA 5I12A 1QUAA 2A8HA 1BUDA 3KMEA 1JK3A 1HY7A 3GBOA 1UMTA 3N2VA 1IAAA 2W15A 3F19A 5B5OA 4WKEA 1KBCA 5BOTA 3SHIA 1IADA 3HY9A 3HBUP 2OXZA 4HMAA 1CGLA 2WO8A 4FVLA 1PWWA 1YOUA 2AIGP 4XCTA 1H71P 3TT4A 2W0DA 2OW9A 5D1SA 4XM8A 3EHYA 2QPJA 1ZS0A 1Z3JA 3WV1A 1R54A 5D1UA 4PKWA 3K7NA 1R55A 3BA0A 3O64A 1SU3A 2HU6A 3P1VA 3U1RA 3OHOA 3WV3A 1BQQM 3DPEA 4WK7A 3DL1A 5CZMA 1G05A 1AF0A 4G0DA 4H76A 1D5JA 4XM7A 4FXQA 1B3DA 966CA 3LJTA 1HFSA 1K7IA 4G9LA 1Y0VA 4PKSA 3RTTA 1C8TA 4IJOA 1YCMA 4GR3A 2MLSA 1B8YA 4A3WA 2MZHA 2WOAA 3P24A 2ERQA 3HB2P 4QKZA 4DPEA 1JH1A 1DTHA 4GWNA 1USNA 4WF6A 3EHXA 2MLRA 3LIRA 1KAPP 5B5PA 2AYKA 2I47A 2K9CA 1ZVXA 4WKIA 1CIZA 4IN9A 2K2GA 5I3MA 1ASTA 1ATLA 1UMSA 1JAPA 3AYKA 1OS9A 1GE7A 3N2UA 1XFUA 2OW1A 2W14A 4GF1A 4FXYP 1R1IA 2E3XA 4Q1LA 4FU4A 1KUKA 3ZUKA 1CQRA 5I4OA 5D2BA 2W12A 3LKAA 1ROSA 1R1HA 3I7GA 1Q3AA 3EDHA 4PKRA 2DW2A 3WV2A 2CLTA 3VI1A 4GUYA 3B2ZA 1KUHA 2POJA 1SLNA 2PJTA 1K7QA 1GO8P 2JT5A 1GE6A 3KHIA 3LEAA 1HTDA 1OO9A 3TS4A 3EDGA 5L7FA 1OM8A 3AYUA 3F18A 1ZXVA 5BOYA 1YQYA 3L0TA 1HFCA 1UEAA 1FM1A 3LE9A 3CKIA 5D7WA 2TCLA 2XS4A 2OXWA 1HOVA 1CAQA 2OVZA 4H84A 4L19A 1OM6A 1FLSA 2OXUA 1DMTA 3LQBA 1A85A 1QJJA 3DWBA 1JANA 5LABA 1CK7A 4H1QA 4IUWA 2ERPA 1ZXCA 2N8RA 2J0TA 1G49A 4H30A 1I73A 1ZTQA 1CGEA 2X3AA 3KEKA 2O3EA 2FV5A 1IACA 3F17A 1JAQA 2OI0A 4JQGA 4JP4A 3OHLA 3B8ZA 3MA2A 2RJPA 3EDZA 1OS2A 1BQOA 3V96B 1G9KA 3K7LA 1PWPA 4ILWD 4JA1A 4AIGA 1XFZA 1L6JA 2YB9A 3L0VA 4H82A 1BKCA 2OW2A 1MMPA 4GWMA 4PKTA 2OZRA 2KRJA 1KUIA 4H2EA 3LGPA 4PKVA 1JKYA 3LJZA 1GXDA 3LIKA 1BIWA 1XFVA 1O0TA 3HBVP 1UTZA 2SRTA 3EDIA 1BSWA 1GKDA 1XFWA 1ND1A 4CTHA 4AUOA 3I7IA 4GQLA 1QIBA 4L6TA 2XS3A 2W13A 4H49A 1WNIA 3LUMA 1PWVA 2DW0A 2EROA 2V4BA 5CXAA 1ZP5A 4WZVA 3TVCA 4JPAA 1KUGA 1D8MA 5CUHA 1G4KA 2FV9A 2X3BA 4J4MA 1UTTA 1C3IA 3LILA 1MMRA 3Q2GA 3KEJA 4L63A 1JJ9A 1JIWP 2D1NA 1XUCA 2J83A 1RM8A 2RJQA 1GO7P 1BUVM 3KECA 1D7XA 1BKCI 1SMPA 3F15A 3ZXHA 1OM7A 1AYKA 2CKIA 1Y93A 3G5CA 2JSDA 1QICA 2JNPA 1KUFA 5BPAA 2MZIA 2JT6A 4A7BA 4DF9A 1BKCE 2USNA 1RMZA 3HDAP 1GKCA 3USNA 2JIHA 4ON1A 3LMCA 1I1IP 4GR8A 3HYGA 1YP1A 2OY2A 1G12A 2OY4A 3LUNA 1QJIA 2L0RA 4I35A 5D3CA 3DPFA 1EB6A 3KMCA 5I43A 1XURA 1O0QA 3KRYA 1BM6A 2OVXA 1MNCA 3TSKA
chains in the Genus database with same CATH superfamily
1GE5A 1A86A 4ZR5A 5H8XA 1HV5A 3NX7A 2O36A 2Y6DA 1PWQA 3LK8A 1XAXA 3ZVSA 3Q2HA 1XFXA 2D1OA 3G42A 1OMJA 1MMBA 830CA 2OW0A 3EWJA 3VTGA 3LQ0A 4PKQA 3DSLA 4JIJA 1EAKA 2Z2DA 3HY7A 4R3VA 1Y8JA 3E8RA 1SATA 5L79A 5I0LA 1CXVA 3F16A 2X3CA 3DNGA 3KWVC 1AKLA 4I03A 1J7NA 2DW1A 1MMQA 2Y6CA 1SLMA 1K7GA 1XUDA 1SRPA 4XM6A 1BZSA 1FBLA 1EUBA 1QIAA 4AYKA 1D8FA 2DDYA 4HX3A 1R1JA 3UVCA 4AXQA 1S4BP 1CGFA 5I2ZA 1JIZA 3ELMA 1IAEA 2DDFA 1PWUA 3LJGA 4H3XA 1IAGA 2YIGA 1C7KA 456CA 1XM5A 1I76A 4EFSA 4GR0A 1JAOA 3DTEA 5JMYA 1IABA 4DV8A 3HDBA 2WO9A 4PKUA 4DD8A 2MZEA 3F1AA 3RTSA 1XFYA 2X7MA 3AIGA 3B92A 3O2XA 4XBHA 2E2DA 5D1TA 5I12A 1QUAA 2A8HA 1BUDA 3KMEA 1JK3A 1HY7A 3GBOA 1UMTA 3N2VA 1IAAA 2W15A 3F19A 5B5OA 4WKEA 1KBCA 5BOTA 3SHIA 1IADA 3HY9A 3HBUP 2OXZA 4HMAA 1CGLA 2WO8A 4FVLA 1PWWA 1YOUA 2AIGP 4XCTA 1H71P 3TT4A 2W0DA 2OW9A 5D1SA 4XM8A 3EHYA 2QPJA 1ZS0A 1Z3JA 3WV1A 1R54A 5D1UA 4PKWA 3K7NA 1R55A 3BA0A 3O64A 1SU3A 2HU6A 3P1VA 3U1RA 3OHOA 3WV3A 1BQQM 3DPEA 4WK7A 3DL1A 5CZMA 1G05A 1AF0A 4G0DA 4H76A 1D5JA 4XM7A 4FXQA 1B3DA 966CA 3LJTA 1HFSA 1K7IA 4G9LA 1Y0VA 4PKSA 3RTTA 1C8TA 4IJOA 1YCMA 4GR3A 2MLSA 1B8YA 4A3WA 2YUFA 2MZHA 2WOAA 3P24A 2ERQA 3HB2P 4QKZA 4DPEA 1JH1A 1DTHA 4GWNA 1USNA 4WF6A 3EHXA 2MLRA 3LIRA 1KAPP 5B5PA 2AYKA 2I47A 2K9CA 1ZVXA 4WKIA 1CIZA 4IN9A 2K2GA 5I3MA 1ASTA 1ATLA 1UMSA 1JAPA 3AYKA 1OS9A 1GE7A 3N2UA 1XFUA 2OW1A 2W14A 4GF1A 4FXYP 1R1IA 2E3XA 4Q1LA 4FU4A 1KUKA 3ZUKA 1CQRA 5I4OA 5D2BA 2W12A 3LKAA 1ROSA 1R1HA 3I7GA 1Q3AA 3EDHA 4PKRA 2DW2A 3WV2A 2CLTA 3VI1A 4GUYA 3B2ZA 1KUHA 2POJA 1SLNA 2PJTA 1K7QA 1GO8P 2JT5A 1GE6A 3KHIA 3LEAA 1HTDA 1OO9A 3TS4A 3EDGA 5L7FA 1OM8A 3AYUA 3F18A 1ZXVA 5BOYA 1YQYA 3L0TA 1HFCA 1UEAA 1FM1A 3LE9A 3CKIA 5D7WA 2TCLA 2XS4A 2OXWA 1HOVA 1CAQA 2OVZA 4H84A 4L19A 1OM6A 1FLSA 2OXUA 1DMTA 3LQBA 1A85A 1QJJA 3DWBA 1JANA 5LABA 1CK7A 4H1QA 4IUWA 2ERPA 1ZXCA 2N8RA 2J0TA 1G49A 4H30A 1I73A 1ZTQA 1CGEA 2X3AA 3KEKA 2O3EA 2FV5A 1IACA 3F17A 1JAQA 2OI0A 4JQGA 4JP4A 3OHLA 3B8ZA 3MA2A 2RJPA 3EDZA 1OS2A 1BQOA 3DTKA 3V96B 1G9KA 3K7LA 1PWPA 1TVIA 4ILWD 4JA1A 4AIGA 4L7AA 1XFZA 1L6JA 2YB9A 3L0VA 4H82A 1BKCA 2OW2A 1MMPA 3DTIA 4GWMA 4PKTA 2OZRA 2KRJA 1KUIA 4H2EA 3LGPA 4PKVA 1JKYA 3LJZA 1GXDA 3LIKA 1BIWA 1XFVA 1O0TA 3HBVP 1UTZA 2SRTA 3EDIA 1BSWA 1GKDA 1XFWA 1ND1A 4CTHA 4AUOA 3I7IA 4GQLA 1QIBA 4L6TA 2XS3A 2W13A 4H49A 1WNIA 3LUMA 1PWVA 2DW0A 2EROA 2V4BA 5CXAA 1ZP5A 4WZVA 3TVCA 4JPAA 1KUGA 1D8MA 5CUHA 1G4KA 2FV9A 2X3BA 4J4MA 1UTTA 1C3IA 3LILA 1MMRA 3Q2GA 3KEJA 4L63A 1JJ9A 1JIWP 2D1NA 1XUCA 2J83A 1RM8A 2RJQA 1GO7P 1BUVM 3KECA 1D7XA 1BKCI 1SMPA 3F15A 3ZXHA 1OM7A 1AYKA 2CKIA 1Y93A 3G5CA 2JSDA 1QICA 2JNPA 1KUFA 5BPAA 2MZIA 2JT6A 4A7BA 4DF9A 1BKCE 2USNA 1RMZA 3HDAP 1GKCA 3USNA 2JIHA 4ON1A 3LMCA 1I1IP 4GR8A 3HYGA 1YP1A 1OZ9A 2OY2A 1G12A 2OY4A 3LUNA 1QJIA 2L0RA 4I35A 5D3CA 3DPFA 1EB6A 3KMCA 5I43A 1XURA 1O0QA 3KRYA 1BM6A 2OVXA 1MNCA 3TSKA
chains in the Genus database with same CATH topology
1GE5A 1A86A 4ZR5A 5H8XA 1HV5A 3NX7A 2O36A 2Y6DA 1PWQA 3LK8A 3ZVSA 3Q2HA 1XFXA 2D1OA 3G42A 1OMJA 1MMBA 830CA 2OW0A 3EWJA 3VTGA 3LQ0A 4PKQA 3DSLA 4JIJA 1EAKA 2Z2DA 3HY7A 4R3VA 1Y8JA 3E8RA 1SATA 5L79A 5I0LA 1CXVA 3F16A 2X3CA 3DNGA 3KWVC 1AKLA 4I03A 1J7NA 2DW1A 1MMQA 2Y6CA 1SLMA 1K7GA 1XUDA 1SRPA 4XM6A 1BZSA 1FBLA 1EUBA 1QIAA 4AYKA 1D8FA 2DDYA 4HX3A 1R1JA 3UVCA 4AXQA 1S4BP 1CGFA 5I2ZA 1JIZA 3ELMA 1IAEA 2DDFA 1PWUA 3LJGA 4H3XA 1IAGA 2YIGA 1C7KA 456CA 1I76A 4EFSA 4GR0A 1JAOA 3DTEA 5JMYA 1IABA 4DV8A 3HDBA 2WO9A 4PKUA 4DD8A 2MZEA 3F1AA 3RTSA 1XFYA 2X7MA 3AIGA 3B92A 3O2XA 4XBHA 2E2DA 5D1TA 5I12A 1QUAA 2A8HA 1BUDA 3KMEA 1JK3A 1HY7A 3GBOA 1UMTA 3N2VA 1IAAA 2W15A 3F19A 5B5OA 4WKEA 1KBCA 5BOTA 3SHIA 1IADA 3HY9A 3HBUP 2OXZA 4HMAA 1CGLA 2WO8A 4FVLA 1PWWA 1YOUA 2AIGP 4XCTA 1H71P 3TT4A 2W0DA 2OW9A 5D1SA 4XM8A 3EHYA 2QPJA 1ZS0A 1Z3JA 3WV1A 1R54A 5D1UA 4PKWA 3K7NA 1R55A 3BA0A 3O64A 1SU3A 2HU6A 3P1VA 3U1RA 3OHOA 3WV3A 1BQQM 3DPEA 4WK7A 3DL1A 5CZMA 1G05A 1AF0A 4G0DA 4H76A 1D5JA 4XM7A 4FXQA 1B3DA 966CA 3LJTA 1HFSA 1K7IA 4G9LA 1Y0VA 4PKSA 3RTTA 1C8TA 4IJOA 1YCMA 4GR3A 2MLSA 1B8YA 4A3WA 2YUFA 2MZHA 2WOAA 3P24A 2ERQA 3HB2P 4QKZA 4DPEA 1JH1A 1DTHA 4GWNA 1USNA 4WF6A 3EHXA 2MLRA 3LIRA 1KAPP 5B5PA 2AYKA 2I47A 2K9CA 1ZVXA 4WKIA 1CIZA 4IN9A 2K2GA 5I3MA 1ASTA 1ATLA 1UMSA 1JAPA 3AYKA 1OS9A 1GE7A 3N2UA 1XFUA 2OW1A 2W14A 4GF1A 4FXYP 1R1IA 2E3XA 4Q1LA 4FU4A 1KUKA 3ZUKA 1CQRA 5I4OA 5D2BA 2W12A 3LKAA 1ROSA 1R1HA 3I7GA 1Q3AA 3EDHA 4PKRA 2DW2A 3WV2A 2CLTA 3VI1A 4GUYA 3B2ZA 1KUHA 2POJA 1SLNA 2PJTA 1K7QA 1GO8P 2JT5A 1GE6A 3KHIA 3LEAA 1HTDA 1OO9A 3TS4A 3EDGA 5L7FA 1OM8A 3AYUA 3F18A 1ZXVA 5BOYA 1YQYA 3L0TA 1HFCA 1UEAA 1FM1A 3LE9A 3CKIA 5D7WA 2TCLA 2XS4A 2OXWA 1HOVA 1CAQA 2OVZA 4H84A 4L19A 1OM6A 1FLSA 2OXUA 1DMTA 3LQBA 1A85A 1QJJA 3DWBA 1JANA 5LABA 1CK7A 4H1QA 4IUWA 2ERPA 1ZXCA 2N8RA 2J0TA 1G49A 4H30A 1I73A 1ZTQA 1CGEA 2X3AA 3KEKA 2O3EA 2FV5A 1IACA 3F17A 1JAQA 2OI0A 4JQGA 4JP4A 3OHLA 3B8ZA 3MA2A 2RJPA 3EDZA 1OS2A 1BQOA 3DTKA 3V96B 1G9KA 3K7LA 1PWPA 4ILWD 4JA1A 4AIGA 4L7AA 1XFZA 1L6JA 2YB9A 3L0VA 4H82A 1BKCA 2OW2A 1MMPA 3DTIA 4GWMA 4PKTA 2OZRA 2KRJA 1KUIA 4H2EA 3LGPA 4PKVA 1JKYA 3LJZA 1GXDA 3LIKA 1BIWA 1XFVA 1O0TA 3HBVP 1UTZA 2SRTA 3EDIA 1BSWA 1GKDA 1XFWA 1ND1A 4CTHA 4AUOA 3I7IA 4GQLA 1QIBA 4L6TA 2XS3A 2W13A 4H49A 1WNIA 3LUMA 1PWVA 2DW0A 2EROA 2V4BA 5CXAA 1ZP5A 4WZVA 3TVCA 4JPAA 1KUGA 1D8MA 5CUHA 1G4KA 2FV9A 2X3BA 4J4MA 1UTTA 1C3IA 3LILA 1MMRA 3Q2GA 3KEJA 4L63A 1JJ9A 1JIWP 2D1NA 1XUCA 2J83A 1RM8A 2RJQA 1GO7P 1BUVM 3KECA 1D7XA 1BKCI 1SMPA 3F15A 3ZXHA 1OM7A 1AYKA 2CKIA 1Y93A 3G5CA 2JSDA 1QICA 2JNPA 1KUFA 5BPAA 2MZIA 2JT6A 4A7BA 4DF9A 1BKCE 2USNA 1RMZA 3HDAP 1GKCA 3USNA 2JIHA 4ON1A 3LMCA 1I1IP 4GR8A 3HYGA 1YP1A 2OY2A 1G12A 2OY4A 3LUNA 1QJIA 2L0RA 4I35A 5D3CA 3DPFA 1EB6A 3KMCA 5I43A 1XURA 1O0QA 3KRYA 1BM6A 2OVXA 1MNCA 3TSKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GE5 A;  1A86 A;  4ZR5 A;  5H8X A;  1HV5 A;  3NX7 A;  2O36 A;  2Y6D A;  1PWQ A;  3LK8 A;  3ZVS A;  3Q2H A;  1XFX A;  2D1O A;  3G42 A;  1OMJ A;  1MMB A;  830C A;  2OW0 A;  3EWJ A;  3VTG A;  3LQ0 A;  4PKQ A;  3DSL A;  4JIJ A;  1EAK A;  2Z2D A;  3HY7 A;  4R3V A;  1Y8J A;  3E8R A;  1SAT A;  5L79 A;  5I0L A;  1CXV A;  3F16 A;  2X3C A;  3DNG A;  3KWV C;  1AKL A;  4I03 A;  1J7N A;  2DW1 A;  1MMQ A;  2Y6C A;  1SLM A;  1K7G A;  1XUD A;  1SRP A;  4XM6 A;  1BZS A;  1FBL A;  1EUB A;  1QIA A;  4AYK A;  1D8F A;  2DDY A;  4HX3 A;  1R1J A;  3UVC A;  4AXQ A;  1S4B P;  1CGF A;  5I2Z A;  1JIZ A;  3ELM A;  1IAE A;  2DDF A;  1PWU A;  3LJG A;  4H3X A;  1IAG A;  2YIG A;  1C7K A;  456C A;  1I76 A;  4EFS A;  4GR0 A;  1JAO A;  5JMY A;  1IAB A;  4DV8 A;  3HDB A;  2WO9 A;  4PKU A;  4DD8 A;  2MZE A;  3F1A A;  3RTS A;  1XFY A;  2X7M A;  3AIG A;  3B92 A;  3O2X A;  4XBH A;  2E2D A;  5D1T A;  5I12 A;  1QUA A;  2A8H A;  1BUD A;  3KME A;  1JK3 A;  1HY7 A;  3GBO A;  1UMT A;  3N2V A;  1IAA A;  2W15 A;  3F19 A;  5B5O A;  4WKE A;  1KBC A;  5BOT A;  3SHI A;  1IAD A;  3HY9 A;  3HBU P;  2OXZ A;  4HMA A;  1CGL A;  2WO8 A;  4FVL A;  1PWW A;  1YOU A;  2AIG P;  4XCT A;  1H71 P;  3TT4 A;  2W0D A;  2OW9 A;  5D1S A;  4XM8 A;  3EHY A;  2QPJ A;  1ZS0 A;  1Z3J A;  3WV1 A;  1R54 A;  5D1U A;  4PKW A;  3K7N A;  1R55 A;  3BA0 A;  3O64 A;  1SU3 A;  2HU6 A;  3P1V A;  3U1R A;  3OHO A;  3WV3 A;  1BQQ M;  3DPE A;  4WK7 A;  3DL1 A;  5CZM A;  1G05 A;  1AF0 A;  4G0D A;  4H76 A;  1D5J A;  4XM7 A;  4FXQ A;  1B3D A;  966C A;  3LJT A;  1HFS A;  1K7I A;  4G9L A;  1Y0V A;  4PKS A;  3RTT A;  1C8T A;  4IJO A;  1YCM A;  4GR3 A;  2MLS A;  1B8Y A;  4A3W A;  2MZH A;  2WOA A;  3P24 A;  2ERQ A;  3HB2 P;  4QKZ A;  4DPE A;  1JH1 A;  1DTH A;  4GWN A;  1USN A;  4WF6 A;  3EHX A;  2MLR A;  3LIR A;  1KAP P;  5B5P A;  2AYK A;  2I47 A;  2K9C A;  1ZVX A;  4WKI A;  1CIZ A;  4IN9 A;  2K2G A;  5I3M A;  1AST A;  1ATL A;  1UMS A;  1JAP A;  3AYK A;  1OS9 A;  1GE7 A;  3N2U A;  1XFU A;  2OW1 A;  2W14 A;  4GF1 A;  4FXY P;  1R1I A;  2E3X A;  4Q1L A;  4FU4 A;  1KUK A;  3ZUK A;  1CQR A;  5I4O A;  5D2B A;  2W12 A;  3LKA A;  1ROS A;  1R1H A;  3I7G A;  1Q3A A;  3EDH A;  4PKR A;  2DW2 A;  3WV2 A;  2CLT A;  3VI1 A;  4GUY A;  3B2Z A;  1KUH A;  2POJ A;  1SLN A;  2PJT A;  1K7Q A;  1GO8 P;  2JT5 A;  1GE6 A;  3KHI A;  3LEA A;  1HTD A;  1OO9 A;  3TS4 A;  3EDG A;  5L7F A;  1OM8 A;  3AYU A;  3F18 A;  1ZXV A;  5BOY A;  1YQY A;  3L0T A;  1HFC A;  1UEA A;  1FM1 A;  3LE9 A;  3CKI A;  5D7W A;  2TCL A;  2XS4 A;  2OXW A;  1HOV A;  1CAQ A;  2OVZ A;  4H84 A;  4L19 A;  1OM6 A;  1FLS A;  2OXU A;  1DMT A;  3LQB A;  1A85 A;  1QJJ A;  3DWB A;  1JAN A;  5LAB A;  1CK7 A;  4H1Q A;  4IUW A;  2ERP A;  1ZXC A;  2N8R A;  2J0T A;  1G49 A;  4H30 A;  1I73 A;  1ZTQ A;  1CGE A;  2X3A A;  3KEK A;  2O3E A;  2FV5 A;  1IAC A;  3F17 A;  1JAQ A;  2OI0 A;  4JQG A;  4JP4 A;  3OHL A;  3B8Z A;  3MA2 A;  2RJP A;  3EDZ A;  1OS2 A;  1BQO A;  3V96 B;  1G9K A;  3K7L A;  1PWP A;  4ILW D;  4JA1 A;  4AIG A;  1XFZ A;  1L6J A;  2YB9 A;  3L0V A;  4H82 A;  1BKC A;  2OW2 A;  1MMP A;  4GWM A;  4PKT A;  2OZR A;  2KRJ A;  1KUI A;  4H2E A;  3LGP A;  4PKV A;  1JKY A;  3LJZ A;  1GXD A;  3LIK A;  1BIW A;  1XFV A;  1O0T A;  3HBV P;  1UTZ A;  2SRT A;  3EDI A;  1BSW A;  1GKD A;  1XFW A;  1ND1 A;  4CTH A;  4AUO A;  3I7I A;  4GQL A;  1QIB A;  4L6T A;  2XS3 A;  2W13 A;  4H49 A;  1WNI A;  3LUM A;  1PWV A;  2DW0 A;  2ERO A;  2V4B A;  5CXA A;  1ZP5 A;  4WZV A;  3TVC A;  4JPA A;  1KUG A;  1D8M A;  5CUH A;  1G4K A;  2FV9 A;  2X3B A;  4J4M A;  1UTT A;  1C3I A;  3LIL A;  1MMR A;  3Q2G A;  3KEJ A;  4L63 A;  1JJ9 A;  1JIW P;  2D1N A;  1XUC A;  2J83 A;  1RM8 A;  2RJQ A;  1GO7 P;  1BUV M;  3KEC A;  1D7X A;  1BKC I;  1SMP A;  3F15 A;  3ZXH A;  1OM7 A;  1AYK A;  2CKI A;  1Y93 A;  3G5C A;  2JSD A;  1QIC A;  2JNP A;  1KUF A;  5BPA A;  2MZI A;  2JT6 A;  4A7B A;  4DF9 A;  1BKC E;  2USN A;  1RMZ A;  3HDA P;  1GKC A;  3USN A;  2JIH A;  4ON1 A;  3LMC A;  1I1I P;  4GR8 A;  3HYG A;  1YP1 A;  2OY2 A;  1G12 A;  2OY4 A;  3LUN A;  1QJI A;  2L0R A;  4I35 A;  5D3C A;  3DPF A;  1EB6 A;  3KMC A;  5I43 A;  1XUR A;  1O0Q A;  3KRY A;  1BM6 A;  2OVX A;  1MNC A;  3TSK A; 
#chains in the Genus database with same CATH topology
 1GE5 A;  1A86 A;  4ZR5 A;  5H8X A;  1HV5 A;  3NX7 A;  2O36 A;  2Y6D A;  1PWQ A;  3LK8 A;  1XAX A;  3ZVS A;  3Q2H A;  1XFX A;  2D1O A;  3G42 A;  1OMJ A;  1MMB A;  830C A;  2OW0 A;  3EWJ A;  3VTG A;  3LQ0 A;  4PKQ A;  3DSL A;  4JIJ A;  1EAK A;  2Z2D A;  3HY7 A;  4R3V A;  1Y8J A;  3E8R A;  1SAT A;  5L79 A;  5I0L A;  1CXV A;  3F16 A;  2X3C A;  3DNG A;  3KWV C;  1AKL A;  4I03 A;  1J7N A;  2DW1 A;  1MMQ A;  2Y6C A;  1SLM A;  1K7G A;  1XUD A;  1SRP A;  4XM6 A;  1BZS A;  1FBL A;  1EUB A;  1QIA A;  4AYK A;  1D8F A;  2DDY A;  4HX3 A;  1R1J A;  3UVC A;  4AXQ A;  1S4B P;  1CGF A;  5I2Z A;  1JIZ A;  3ELM A;  1IAE A;  2DDF A;  1PWU A;  3LJG A;  4H3X A;  1IAG A;  2YIG A;  1C7K A;  456C A;  1XM5 A;  1I76 A;  4EFS A;  4GR0 A;  1JAO A;  3DTE A;  5JMY A;  1IAB A;  4DV8 A;  3HDB A;  2WO9 A;  4PKU A;  4DD8 A;  2MZE A;  3F1A A;  3RTS A;  1XFY A;  2X7M A;  3AIG A;  3B92 A;  3O2X A;  4XBH A;  2E2D A;  5D1T A;  5I12 A;  1QUA A;  2A8H A;  1BUD A;  3KME A;  1JK3 A;  1HY7 A;  3GBO A;  1UMT A;  3N2V A;  1IAA A;  2W15 A;  3F19 A;  5B5O A;  4WKE A;  1KBC A;  5BOT A;  3SHI A;  1IAD A;  3HY9 A;  3HBU P;  2OXZ A;  4HMA A;  1CGL A;  2WO8 A;  4FVL A;  1PWW A;  1YOU A;  2AIG P;  4XCT A;  1H71 P;  3TT4 A;  2W0D A;  2OW9 A;  5D1S A;  4XM8 A;  3EHY A;  2QPJ A;  1ZS0 A;  1Z3J A;  3WV1 A;  1R54 A;  5D1U A;  4PKW A;  3K7N A;  1R55 A;  3BA0 A;  3O64 A;  1SU3 A;  2HU6 A;  3P1V A;  3U1R A;  3OHO A;  3WV3 A;  1BQQ M;  3DPE A;  4WK7 A;  3DL1 A;  5CZM A;  1G05 A;  1AF0 A;  4G0D A;  4H76 A;  1D5J A;  4XM7 A;  4FXQ A;  1B3D A;  966C A;  3LJT A;  1HFS A;  1K7I A;  4G9L A;  1Y0V A;  4PKS A;  3RTT A;  1C8T A;  4IJO A;  1YCM A;  4GR3 A;  2MLS A;  1B8Y A;  4A3W A;  2YUF A;  2MZH A;  2WOA A;  3P24 A;  2ERQ A;  3HB2 P;  4QKZ A;  4DPE A;  1JH1 A;  1DTH A;  4GWN A;  1USN A;  4WF6 A;  3EHX A;  2MLR A;  3LIR A;  1KAP P;  5B5P A;  2AYK A;  2I47 A;  2K9C A;  1ZVX A;  4WKI A;  1CIZ A;  4IN9 A;  2K2G A;  5I3M A;  1AST A;  1ATL A;  1UMS A;  1JAP A;  3AYK A;  1OS9 A;  1GE7 A;  3N2U A;  1XFU A;  2OW1 A;  2W14 A;  4GF1 A;  4FXY P;  1R1I A;  2E3X A;  4Q1L A;  4FU4 A;  1KUK A;  3ZUK A;  1CQR A;  5I4O A;  5D2B A;  2W12 A;  3LKA A;  1ROS A;  1R1H A;  3I7G A;  1Q3A A;  3EDH A;  4PKR A;  2DW2 A;  3WV2 A;  2CLT A;  3VI1 A;  4GUY A;  3B2Z A;  1KUH A;  2POJ A;  1SLN A;  2PJT A;  1K7Q A;  1GO8 P;  2JT5 A;  1GE6 A;  3KHI A;  3LEA A;  1HTD A;  1OO9 A;  3TS4 A;  3EDG A;  5L7F A;  1OM8 A;  3AYU A;  3F18 A;  1ZXV A;  5BOY A;  1YQY A;  3L0T A;  1HFC A;  1UEA A;  1FM1 A;  3LE9 A;  3CKI A;  5D7W A;  2TCL A;  2XS4 A;  2OXW A;  1HOV A;  1CAQ A;  2OVZ A;  4H84 A;  4L19 A;  1OM6 A;  1FLS A;  2OXU A;  1DMT A;  3LQB A;  1A85 A;  1QJJ A;  3DWB A;  1JAN A;  5LAB A;  1CK7 A;  4H1Q A;  4IUW A;  2ERP A;  1ZXC A;  2N8R A;  2J0T A;  1G49 A;  4H30 A;  1I73 A;  1ZTQ A;  1CGE A;  2X3A A;  3KEK A;  2O3E A;  2FV5 A;  1IAC A;  3F17 A;  1JAQ A;  2OI0 A;  4JQG A;  4JP4 A;  3OHL A;  3B8Z A;  3MA2 A;  2RJP A;  3EDZ A;  1OS2 A;  1BQO A;  3DTK A;  3V96 B;  1G9K A;  3K7L A;  1PWP A;  1TVI A;  4ILW D;  4JA1 A;  4AIG A;  4L7A A;  1XFZ A;  1L6J A;  2YB9 A;  3L0V A;  4H82 A;  1BKC A;  2OW2 A;  1MMP A;  3DTI A;  4GWM A;  4PKT A;  2OZR A;  2KRJ A;  1KUI A;  4H2E A;  3LGP A;  4PKV A;  1JKY A;  3LJZ A;  1GXD A;  3LIK A;  1BIW A;  1XFV A;  1O0T A;  3HBV P;  1UTZ A;  2SRT A;  3EDI A;  1BSW A;  1GKD A;  1XFW A;  1ND1 A;  4CTH A;  4AUO A;  3I7I A;  4GQL A;  1QIB A;  4L6T A;  2XS3 A;  2W13 A;  4H49 A;  1WNI A;  3LUM A;  1PWV A;  2DW0 A;  2ERO A;  2V4B A;  5CXA A;  1ZP5 A;  4WZV A;  3TVC A;  4JPA A;  1KUG A;  1D8M A;  5CUH A;  1G4K A;  2FV9 A;  2X3B A;  4J4M A;  1UTT A;  1C3I A;  3LIL A;  1MMR A;  3Q2G A;  3KEJ A;  4L63 A;  1JJ9 A;  1JIW P;  2D1N A;  1XUC A;  2J83 A;  1RM8 A;  2RJQ A;  1GO7 P;  1BUV M;  3KEC A;  1D7X A;  1BKC I;  1SMP A;  3F15 A;  3ZXH A;  1OM7 A;  1AYK A;  2CKI A;  1Y93 A;  3G5C A;  2JSD A;  1QIC A;  2JNP A;  1KUF A;  5BPA A;  2MZI A;  2JT6 A;  4A7B A;  4DF9 A;  1BKC E;  2USN A;  1RMZ A;  3HDA P;  1GKC A;  3USN A;  2JIH A;  4ON1 A;  3LMC A;  1I1I P;  4GR8 A;  3HYG A;  1YP1 A;  1OZ9 A;  2OY2 A;  1G12 A;  2OY4 A;  3LUN A;  1QJI A;  2L0R A;  4I35 A;  5D3C A;  3DPF A;  1EB6 A;  3KMC A;  5I43 A;  1XUR A;  1O0Q A;  3KRY A;  1BM6 A;  2OVX A;  1MNC A;  3TSK A; 
#chains in the Genus database with same CATH homology
 1GE5 A;  1A86 A;  4ZR5 A;  5H8X A;  1HV5 A;  3NX7 A;  2O36 A;  2Y6D A;  1PWQ A;  3LK8 A;  3ZVS A;  3Q2H A;  1XFX A;  2D1O A;  3G42 A;  1OMJ A;  1MMB A;  830C A;  2OW0 A;  3EWJ A;  3VTG A;  3LQ0 A;  4PKQ A;  3DSL A;  4JIJ A;  1EAK A;  2Z2D A;  3HY7 A;  4R3V A;  1Y8J A;  3E8R A;  1SAT A;  5L79 A;  5I0L A;  1CXV A;  3F16 A;  2X3C A;  3DNG A;  3KWV C;  1AKL A;  4I03 A;  1J7N A;  2DW1 A;  1MMQ A;  2Y6C A;  1SLM A;  1K7G A;  1XUD A;  1SRP A;  4XM6 A;  1BZS A;  1FBL A;  1EUB A;  1QIA A;  4AYK A;  1D8F A;  2DDY A;  4HX3 A;  1R1J A;  3UVC A;  4AXQ A;  1S4B P;  1CGF A;  5I2Z A;  1JIZ A;  3ELM A;  1IAE A;  2DDF A;  1PWU A;  3LJG A;  4H3X A;  1IAG A;  2YIG A;  1C7K A;  456C A;  1I76 A;  4EFS A;  4GR0 A;  1JAO A;  3DTE A;  5JMY A;  1IAB A;  4DV8 A;  3HDB A;  2WO9 A;  4PKU A;  4DD8 A;  2MZE A;  3F1A A;  3RTS A;  1XFY A;  2X7M A;  3AIG A;  3B92 A;  3O2X A;  4XBH A;  2E2D A;  5D1T A;  5I12 A;  1QUA A;  2A8H A;  1BUD A;  3KME A;  1JK3 A;  1HY7 A;  3GBO A;  1UMT A;  3N2V A;  1IAA A;  2W15 A;  3F19 A;  5B5O A;  4WKE A;  1KBC A;  5BOT A;  3SHI A;  1IAD A;  3HY9 A;  3HBU P;  2OXZ A;  4HMA A;  1CGL A;  2WO8 A;  4FVL A;  1PWW A;  1YOU A;  2AIG P;  4XCT A;  1H71 P;  3TT4 A;  2W0D A;  2OW9 A;  5D1S A;  4XM8 A;  3EHY A;  2QPJ A;  1ZS0 A;  1Z3J A;  3WV1 A;  1R54 A;  5D1U A;  4PKW A;  3K7N A;  1R55 A;  3BA0 A;  3O64 A;  1SU3 A;  2HU6 A;  3P1V A;  3U1R A;  3OHO A;  3WV3 A;  1BQQ M;  3DPE A;  4WK7 A;  3DL1 A;  5CZM A;  1G05 A;  1AF0 A;  4G0D A;  4H76 A;  1D5J A;  4XM7 A;  4FXQ A;  1B3D A;  966C A;  3LJT A;  1HFS A;  1K7I A;  4G9L A;  1Y0V A;  4PKS A;  3RTT A;  1C8T A;  4IJO A;  1YCM A;  4GR3 A;  2MLS A;  1B8Y A;  4A3W A;  2YUF A;  2MZH A;  2WOA A;  3P24 A;  2ERQ A;  3HB2 P;  4QKZ A;  4DPE A;  1JH1 A;  1DTH A;  4GWN A;  1USN A;  4WF6 A;  3EHX A;  2MLR A;  3LIR A;  1KAP P;  5B5P A;  2AYK A;  2I47 A;  2K9C A;  1ZVX A;  4WKI A;  1CIZ A;  4IN9 A;  2K2G A;  5I3M A;  1AST A;  1ATL A;  1UMS A;  1JAP A;  3AYK A;  1OS9 A;  1GE7 A;  3N2U A;  1XFU A;  2OW1 A;  2W14 A;  4GF1 A;  4FXY P;  1R1I A;  2E3X A;  4Q1L A;  4FU4 A;  1KUK A;  3ZUK A;  1CQR A;  5I4O A;  5D2B A;  2W12 A;  3LKA A;  1ROS A;  1R1H A;  3I7G A;  1Q3A A;  3EDH A;  4PKR A;  2DW2 A;  3WV2 A;  2CLT A;  3VI1 A;  4GUY A;  3B2Z A;  1KUH A;  2POJ A;  1SLN A;  2PJT A;  1K7Q A;  1GO8 P;  2JT5 A;  1GE6 A;  3KHI A;  3LEA A;  1HTD A;  1OO9 A;  3TS4 A;  3EDG A;  5L7F A;  1OM8 A;  3AYU A;  3F18 A;  1ZXV A;  5BOY A;  1YQY A;  3L0T A;  1HFC A;  1UEA A;  1FM1 A;  3LE9 A;  3CKI A;  5D7W A;  2TCL A;  2XS4 A;  2OXW A;  1HOV A;  1CAQ A;  2OVZ A;  4H84 A;  4L19 A;  1OM6 A;  1FLS A;  2OXU A;  1DMT A;  3LQB A;  1A85 A;  1QJJ A;  3DWB A;  1JAN A;  5LAB A;  1CK7 A;  4H1Q A;  4IUW A;  2ERP A;  1ZXC A;  2N8R A;  2J0T A;  1G49 A;  4H30 A;  1I73 A;  1ZTQ A;  1CGE A;  2X3A A;  3KEK A;  2O3E A;  2FV5 A;  1IAC A;  3F17 A;  1JAQ A;  2OI0 A;  4JQG A;  4JP4 A;  3OHL A;  3B8Z A;  3MA2 A;  2RJP A;  3EDZ A;  1OS2 A;  1BQO A;  3DTK A;  3V96 B;  1G9K A;  3K7L A;  1PWP A;  4ILW D;  4JA1 A;  4AIG A;  4L7A A;  1XFZ A;  1L6J A;  2YB9 A;  3L0V A;  4H82 A;  1BKC A;  2OW2 A;  1MMP A;  3DTI A;  4GWM A;  4PKT A;  2OZR A;  2KRJ A;  1KUI A;  4H2E A;  3LGP A;  4PKV A;  1JKY A;  3LJZ A;  1GXD A;  3LIK A;  1BIW A;  1XFV A;  1O0T A;  3HBV P;  1UTZ A;  2SRT A;  3EDI A;  1BSW A;  1GKD A;  1XFW A;  1ND1 A;  4CTH A;  4AUO A;  3I7I A;  4GQL A;  1QIB A;  4L6T A;  2XS3 A;  2W13 A;  4H49 A;  1WNI A;  3LUM A;  1PWV A;  2DW0 A;  2ERO A;  2V4B A;  5CXA A;  1ZP5 A;  4WZV A;  3TVC A;  4JPA A;  1KUG A;  1D8M A;  5CUH A;  1G4K A;  2FV9 A;  2X3B A;  4J4M A;  1UTT A;  1C3I A;  3LIL A;  1MMR A;  3Q2G A;  3KEJ A;  4L63 A;  1JJ9 A;  1JIW P;  2D1N A;  1XUC A;  2J83 A;  1RM8 A;  2RJQ A;  1GO7 P;  1BUV M;  3KEC A;  1D7X A;  1BKC I;  1SMP A;  3F15 A;  3ZXH A;  1OM7 A;  1AYK A;  2CKI A;  1Y93 A;  3G5C A;  2JSD A;  1QIC A;  2JNP A;  1KUF A;  5BPA A;  2MZI A;  2JT6 A;  4A7B A;  4DF9 A;  1BKC E;  2USN A;  1RMZ A;  3HDA P;  1GKC A;  3USN A;  2JIH A;  4ON1 A;  3LMC A;  1I1I P;  4GR8 A;  3HYG A;  1YP1 A;  2OY2 A;  1G12 A;  2OY4 A;  3LUN A;  1QJI A;  2L0R A;  4I35 A;  5D3C A;  3DPF A;  1EB6 A;  3KMC A;  5I43 A;  1XUR A;  1O0Q A;  3KRY A;  1BM6 A;  2OVX A;  1MNC A;  3TSK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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