1CIZA

X-ray structure of human stromelysin catalytic domain complexes with non-peptide inhibitors: implication for inhibitor selectivity
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
168
structure length
168
Chain Sequence
FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.
pubmed rcsb
molecule tags Metalloproteinase
source organism Homo sapiens
molecule keywords PROTEIN (STROMELYSIN-1)
total genus 47
structure length 168
sequence length 168
ec nomenclature ec 3.4.24.17: Stromelysin 1.
pdb deposition date 1999-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1cizA00
1JK3A 4ON1A 3E8RA 1R1IA 2TCLA 3WV1A 1IAGA 2Z2DA 3EDZA 3N2UA 3ZXHA 4XM8A 1B8YA 4L6TA 5I4OA 2HU6A 4L63A 4H49A 1Q3AA 4Q1LA 3WV3A 3SHIA 3K7LA 1BQOA 1DTHA 1QICA 2AIGP 3DPFA 5H8XA 2MLRA 1ND1A 3G5CA 3DSLA 1QJJA 2WO9A 2E3XA 1QIAA 4JPAA 4WKIA 5D2BA 1GO7P 3P1VA 1Y8JA 4H2EA 1HFCA 1IAAA 1O0QA 1SU3A 3LUMA 1SRPA 4H82A 4JIJA 4AIGA 3CKIA 2RJPA 1ZXVA 1D7XA 2OW9A 2X7MA 1I73A 1MMPA 1CXVA 4L19A 2DW0A 4PKSA 2Y6DA 1GKDA 4XCTA 3RTSA 2J83A 1JAQA 4PKQA 3HY7A 4H76A 1HFSA 2DW2A 1IABA 3KWVC 4DF9A 3KMCA 3LK8A 4I35A 3LUNA 1JAOA 3U1RA 3TVCA 3GBOA 3OHOA 830CA 4GR0A 1UMSA 3I7GA 2W14A 2DDFA 3NX7A 1CAQA 4J4MA 1C8TA 3TSKA 1PWQA 4JQGA 4PKTA 1PWPA 4HX3A 1O0TA 1QJIA 4XBHA 5D7WA 3LQ0A 5BOTA 1UTTA 4H3XA 2XS3A 3F18A 1BUDA 1YOUA 3V96B 2ERQA 3WV2A 3VTGA 2W13A 1I1IP 2OVXA 2L0RA 1L6JA 2MZHA 4A7BA 3LJZA 1XFZA 1SLNA 2OW0A 3Q2GA 4WK7A 4WF6A 4H1QA 5JMYA 3F16A 4R3VA 3LJTA 2OI0A 3P24A 3EDHA 1USNA 4PKVA 2MLSA 1R55A 2V4BA 2E2DA 2FV5A 2XS4A 3HBUP 1HOVA 1RM8A 2AYKA 4AXQA 2YIGA 3TS4A 1MMQA 2K9CA 1FBLA 1K7GA 1IADA 1G12A 2RJQA 4ILWD 1J7NA 1KUHA 4WZVA 1SATA 1GE6A 1JIWP 2OY4A 2WOAA 3B8ZA 4I03A 2DW1A 3LMCA 1HTDA 3O2XA 1YCMA 1Y93A 1KBCA 1G4KA 1GXDA 4JA1A 1MNCA 3KECA 3DL1A 2JT5A 1H71P 3HB2P 1XFXA 1R1JA 1G05A 1CGEA 3LIRA 3DNGA 2CLTA 2W12A 2CKIA 3I7IA 1C7KA 4FVLA 1BQQM 3KEKA 1PWVA 2W0DA 2QPJA 1OM8A 5L7FA 1XURA 1BKCI 1DMTA 456CA 2OW1A 3O64A 1D5JA 5D3CA 1OS9A 2ERPA 1HV5A 3LILA 3F1AA 2OW2A 1UMTA 1BIWA 4ZR5A 1AKLA 4EFSA 5I43A 1CIZA 1IACA 3HBVP 1XFWA 1AF0A 1KAPP 4FU4A 4G9LA 1OO9A 1JKYA 3KHIA 3TT4A 4FXYP 1BKCA 2PJTA 3B2ZA 2X3BA 1JANA 1S4BP 1PWUA 1C3IA 1KUGA 2D1NA 1WNIA 1QUAA 2POJA 3HYGA 3OHLA 4IN9A 2X3CA 1K7IA 1CGLA 5B5OA 1R1HA 2W15A 2JT6A 1MMRA 3HDBA 4AYKA 3HDAP 1ZS0A 1BSWA 5I12A 3MA2A 2YB9A 5I2ZA 5D1UA 1ASTA 1G49A 4GWNA 3F17A 1ATLA 1XFYA 5LABA 2OXWA 2N8RA 1SMPA 4WKEA 3BA0A 2K2GA 1OMJA 4DD8A 1OM6A 2WO8A 4A3WA 2JIHA 2DDYA 3ZUKA 1D8MA 1ROSA 2JSDA 2X3AA 3AYUA 1MMBA 4QKZA 3EHXA 5B5PA 1FM1A 1FLSA 5I0LA 2A8HA 1XFUA 4CTHA 3Q2HA 1BUVM 4GUYA 4PKRA 1GE5A 1A85A 3ELMA 3EHYA 1XFVA 1XUCA 4GF1A 4GR8A 1Z3JA 1BKCE 1EAKA 2MZIA 3DWBA 2EROA 3LGPA 2Y6CA 1ZXCA 1ZVXA 4PKWA 2USNA 1UTZA 1PWWA 3LKAA 1A86A 4IUWA 1JIZA 1ZTQA 1HY7A 1XUDA 1G9KA 1AYKA 5I3MA 2SRTA 3LE9A 1YP1A 1JJ9A 3UVCA 5D1TA 3ZVSA 3L0VA 3LJGA 1QIBA 5BPAA 4JP4A 3DPEA 1KUIA 4XM6A 1I76A 3AIGA 3G42A 3K7NA 5L79A 4H84A 966CA 4HMAA 4FXQA 5CZMA 2O36A 1GE7A 1JH1A 1GKCA 2J0TA 5D1SA 3F19A 1CGFA 3B92A 3VI1A 1EB6A 4IJOA 1KUFA 1K7QA 1JAPA 1GO8P 2D1OA 1CK7A 1BZSA 1D8FA 1ZP5A 3EWJA 3AYKA 5BOYA 1R54A 4GR3A 2I47A 3F15A 5CXAA 1Y0VA 4PKUA 1KUKA 3KRYA 2OXZA 2OZRA 1CQRA 4AUOA 3EDIA 3RTTA 3KMEA 2OVZA 1BM6A 4XM7A 1B3DA 2MZEA 1EUBA 1OS2A 4H30A 1OM7A 3N2VA 5CUHA 1IAEA 3L0TA 2FV9A 1SLMA 2OY2A 3HY9A 1UEAA 2JNPA 4GWMA 4DV8A 3LIKA 4DPEA 3USNA 3LEAA 4G0DA 3LQBA 2OXUA 2KRJA 1YQYA 3KEJA 4GQLA 3EDGA 1RMZA 2O3EA
chains in the Genus database with same CATH superfamily
1JK3A 4ON1A 3E8RA 1R1IA 2TCLA 3WV1A 1IAGA 2Z2DA 3EDZA 3N2UA 3ZXHA 4XM8A 1B8YA 4L6TA 5I4OA 2HU6A 4L63A 4H49A 1Q3AA 4Q1LA 1XAXA 3WV3A 3SHIA 3K7LA 1BQOA 1DTHA 1QICA 2AIGP 3DPFA 5H8XA 2MLRA 1ND1A 3G5CA 3DSLA 1QJJA 2WO9A 2E3XA 1QIAA 4JPAA 4WKIA 5D2BA 1GO7P 3P1VA 1Y8JA 4H2EA 1HFCA 1IAAA 1O0QA 1SU3A 3LUMA 1SRPA 4H82A 4JIJA 4AIGA 3CKIA 2RJPA 1ZXVA 1D7XA 2OW9A 2X7MA 1I73A 1MMPA 1CXVA 4L19A 2DW0A 4PKSA 2Y6DA 1GKDA 4XCTA 3RTSA 2J83A 1JAQA 4PKQA 3HY7A 4H76A 1HFSA 2DW2A 1IABA 3KWVC 4DF9A 3KMCA 3LK8A 4I35A 3LUNA 1JAOA 3U1RA 3TVCA 3GBOA 3OHOA 830CA 4GR0A 1UMSA 3I7GA 2W14A 2DDFA 3NX7A 1CAQA 4J4MA 1C8TA 3TSKA 1PWQA 4JQGA 4PKTA 1PWPA 4HX3A 1O0TA 1QJIA 4XBHA 5D7WA 3LQ0A 5BOTA 1UTTA 4H3XA 2XS3A 3F18A 1BUDA 1YOUA 3V96B 2ERQA 3WV2A 3VTGA 2W13A 1I1IP 2OVXA 2L0RA 1L6JA 2MZHA 4A7BA 3LJZA 1XFZA 1SLNA 2OW0A 3Q2GA 4WK7A 4WF6A 4H1QA 5JMYA 3F16A 4R3VA 3LJTA 2OI0A 3P24A 3EDHA 1USNA 4PKVA 2MLSA 1R55A 2V4BA 2E2DA 2FV5A 2XS4A 3HBUP 1HOVA 1RM8A 2AYKA 4AXQA 2YIGA 3TS4A 1MMQA 2K9CA 1FBLA 1K7GA 1IADA 1G12A 2RJQA 4ILWD 1J7NA 1KUHA 4WZVA 1OZ9A 1SATA 1GE6A 1JIWP 2OY4A 2WOAA 3B8ZA 3DTIA 4I03A 2DW1A 3LMCA 1HTDA 3O2XA 1YCMA 1Y93A 1KBCA 1G4KA 1GXDA 4JA1A 1MNCA 3KECA 3DL1A 2JT5A 1H71P 3HB2P 1XFXA 1R1JA 1G05A 1CGEA 3LIRA 3DNGA 2CLTA 2W12A 2CKIA 3I7IA 1C7KA 4FVLA 1BQQM 3KEKA 1PWVA 2W0DA 2YUFA 2QPJA 1OM8A 5L7FA 1XURA 1BKCI 1DMTA 3DTEA 456CA 2OW1A 3O64A 1D5JA 5D3CA 1OS9A 2ERPA 1HV5A 3LILA 3F1AA 2OW2A 1UMTA 1BIWA 4ZR5A 1AKLA 4EFSA 5I43A 1CIZA 1IACA 3HBVP 1XFWA 1AF0A 1KAPP 4FU4A 4G9LA 1OO9A 1JKYA 3KHIA 3TT4A 4FXYP 1BKCA 2PJTA 3B2ZA 2X3BA 1JANA 1S4BP 1PWUA 1C3IA 1KUGA 2D1NA 1WNIA 1QUAA 2POJA 3HYGA 3OHLA 4IN9A 2X3CA 1K7IA 1CGLA 4L7AA 5B5OA 3DTKA 1R1HA 2W15A 2JT6A 1MMRA 3HDBA 4AYKA 3HDAP 1ZS0A 1XM5A 1BSWA 5I12A 3MA2A 2YB9A 5I2ZA 5D1UA 1ASTA 1G49A 4GWNA 3F17A 1ATLA 1XFYA 5LABA 2OXWA 2N8RA 1SMPA 4WKEA 3BA0A 2K2GA 1OMJA 4DD8A 1OM6A 2WO8A 4A3WA 2JIHA 2DDYA 3ZUKA 1D8MA 1ROSA 2JSDA 2X3AA 3AYUA 1MMBA 4QKZA 3EHXA 5B5PA 1FM1A 1FLSA 5I0LA 2A8HA 1XFUA 4CTHA 3Q2HA 1BUVM 4GUYA 4PKRA 1GE5A 1A85A 3ELMA 3EHYA 1XFVA 1XUCA 4GF1A 4GR8A 1Z3JA 1BKCE 1EAKA 2MZIA 3DWBA 2EROA 3LGPA 2Y6CA 1ZXCA 1ZVXA 4PKWA 2USNA 1UTZA 1PWWA 1TVIA 3LKAA 1A86A 4IUWA 1JIZA 1ZTQA 1HY7A 1XUDA 1G9KA 1AYKA 5I3MA 2SRTA 3LE9A 1YP1A 1JJ9A 3UVCA 5D1TA 3ZVSA 3L0VA 3LJGA 1QIBA 5BPAA 4JP4A 3DPEA 1KUIA 4XM6A 1I76A 3AIGA 3G42A 3K7NA 5L79A 4H84A 966CA 4HMAA 4FXQA 5CZMA 2O36A 1GE7A 1JH1A 1GKCA 2J0TA 5D1SA 3F19A 1CGFA 3B92A 3VI1A 1EB6A 4IJOA 1KUFA 1K7QA 1JAPA 1GO8P 2D1OA 1CK7A 1BZSA 1D8FA 1ZP5A 3EWJA 3AYKA 5BOYA 1R54A 4GR3A 2I47A 3F15A 5CXAA 1Y0VA 4PKUA 1KUKA 3KRYA 2OXZA 2OZRA 1CQRA 4AUOA 3EDIA 3RTTA 3KMEA 2OVZA 1BM6A 4XM7A 1B3DA 2MZEA 1EUBA 1OS2A 4H30A 1OM7A 3N2VA 5CUHA 1IAEA 3L0TA 2FV9A 1SLMA 2OY2A 3HY9A 1UEAA 2JNPA 4GWMA 4DV8A 3LIKA 4DPEA 3USNA 3LEAA 4G0DA 3LQBA 2OXUA 2KRJA 1YQYA 3KEJA 4GQLA 3EDGA 1RMZA 2O3EA
chains in the Genus database with same CATH topology
1JK3A 4ON1A 3E8RA 1R1IA 2TCLA 3WV1A 1IAGA 2Z2DA 3EDZA 3N2UA 3ZXHA 4XM8A 1B8YA 4L6TA 5I4OA 2HU6A 4L63A 4H49A 1Q3AA 4Q1LA 3WV3A 3SHIA 3K7LA 1BQOA 1DTHA 1QICA 2AIGP 3DPFA 5H8XA 2MLRA 1ND1A 3G5CA 3DSLA 1QJJA 2WO9A 2E3XA 1QIAA 4JPAA 4WKIA 5D2BA 1GO7P 3P1VA 1Y8JA 4H2EA 1HFCA 1IAAA 1O0QA 1SU3A 3LUMA 1SRPA 4H82A 4JIJA 4AIGA 3CKIA 2RJPA 1ZXVA 1D7XA 2OW9A 2X7MA 1I73A 1MMPA 1CXVA 4L19A 2DW0A 4PKSA 2Y6DA 1GKDA 4XCTA 3RTSA 2J83A 1JAQA 4PKQA 3HY7A 4H76A 1HFSA 2DW2A 1IABA 3KWVC 4DF9A 3KMCA 3LK8A 4I35A 3LUNA 1JAOA 3U1RA 3TVCA 3GBOA 3OHOA 830CA 4GR0A 1UMSA 3I7GA 2W14A 2DDFA 3NX7A 1CAQA 4J4MA 1C8TA 3TSKA 1PWQA 4JQGA 4PKTA 1PWPA 4HX3A 1O0TA 1QJIA 4XBHA 5D7WA 3LQ0A 5BOTA 1UTTA 4H3XA 2XS3A 3F18A 1BUDA 1YOUA 3V96B 2ERQA 3WV2A 3VTGA 2W13A 1I1IP 2OVXA 2L0RA 1L6JA 2MZHA 4A7BA 3LJZA 1XFZA 1SLNA 2OW0A 3Q2GA 4WK7A 4WF6A 4H1QA 5JMYA 3F16A 4R3VA 3LJTA 2OI0A 3P24A 3EDHA 1USNA 4PKVA 2MLSA 1R55A 2V4BA 2E2DA 2FV5A 2XS4A 3HBUP 1HOVA 1RM8A 2AYKA 4AXQA 2YIGA 3TS4A 1MMQA 2K9CA 1FBLA 1K7GA 1IADA 1G12A 2RJQA 4ILWD 1J7NA 1KUHA 4WZVA 1SATA 1GE6A 1JIWP 2OY4A 2WOAA 3B8ZA 3DTIA 4I03A 2DW1A 3LMCA 1HTDA 3O2XA 1YCMA 1Y93A 1KBCA 1G4KA 1GXDA 4JA1A 1MNCA 3KECA 3DL1A 2JT5A 1H71P 3HB2P 1XFXA 1R1JA 1G05A 1CGEA 3LIRA 3DNGA 2CLTA 2W12A 2CKIA 3I7IA 1C7KA 4FVLA 1BQQM 3KEKA 1PWVA 2W0DA 2YUFA 2QPJA 1OM8A 5L7FA 1XURA 1BKCI 1DMTA 3DTEA 456CA 2OW1A 3O64A 1D5JA 5D3CA 1OS9A 2ERPA 1HV5A 3LILA 3F1AA 2OW2A 1UMTA 1BIWA 4ZR5A 1AKLA 4EFSA 5I43A 1CIZA 1IACA 3HBVP 1XFWA 1AF0A 1KAPP 4FU4A 4G9LA 1OO9A 1JKYA 3KHIA 3TT4A 4FXYP 1BKCA 2PJTA 3B2ZA 2X3BA 1JANA 1S4BP 1PWUA 1C3IA 1KUGA 2D1NA 1WNIA 1QUAA 2POJA 3HYGA 3OHLA 4IN9A 2X3CA 1K7IA 1CGLA 4L7AA 5B5OA 3DTKA 1R1HA 2W15A 2JT6A 1MMRA 3HDBA 4AYKA 3HDAP 1ZS0A 1BSWA 5I12A 3MA2A 2YB9A 5I2ZA 5D1UA 1ASTA 1G49A 4GWNA 3F17A 1ATLA 1XFYA 5LABA 2OXWA 2N8RA 1SMPA 4WKEA 3BA0A 2K2GA 1OMJA 4DD8A 1OM6A 2WO8A 4A3WA 2JIHA 2DDYA 3ZUKA 1D8MA 1ROSA 2JSDA 2X3AA 3AYUA 1MMBA 4QKZA 3EHXA 5B5PA 1FM1A 1FLSA 5I0LA 2A8HA 1XFUA 4CTHA 3Q2HA 1BUVM 4GUYA 4PKRA 1GE5A 1A85A 3ELMA 3EHYA 1XFVA 1XUCA 4GF1A 4GR8A 1Z3JA 1BKCE 1EAKA 2MZIA 3DWBA 2EROA 3LGPA 2Y6CA 1ZXCA 1ZVXA 4PKWA 2USNA 1UTZA 1PWWA 3LKAA 1A86A 4IUWA 1JIZA 1ZTQA 1HY7A 1XUDA 1G9KA 1AYKA 5I3MA 2SRTA 3LE9A 1YP1A 1JJ9A 3UVCA 5D1TA 3ZVSA 3L0VA 3LJGA 1QIBA 5BPAA 4JP4A 3DPEA 1KUIA 4XM6A 1I76A 3AIGA 3G42A 3K7NA 5L79A 4H84A 966CA 4HMAA 4FXQA 5CZMA 2O36A 1GE7A 1JH1A 1GKCA 2J0TA 5D1SA 3F19A 1CGFA 3B92A 3VI1A 1EB6A 4IJOA 1KUFA 1K7QA 1JAPA 1GO8P 2D1OA 1CK7A 1BZSA 1D8FA 1ZP5A 3EWJA 3AYKA 5BOYA 1R54A 4GR3A 2I47A 3F15A 5CXAA 1Y0VA 4PKUA 1KUKA 3KRYA 2OXZA 2OZRA 1CQRA 4AUOA 3EDIA 3RTTA 3KMEA 2OVZA 1BM6A 4XM7A 1B3DA 2MZEA 1EUBA 1OS2A 4H30A 1OM7A 3N2VA 5CUHA 1IAEA 3L0TA 2FV9A 1SLMA 2OY2A 3HY9A 1UEAA 2JNPA 4GWMA 4DV8A 3LIKA 4DPEA 3USNA 3LEAA 4G0DA 3LQBA 2OXUA 2KRJA 1YQYA 3KEJA 4GQLA 3EDGA 1RMZA 2O3EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JK3 A;  4ON1 A;  3E8R A;  1R1I A;  2TCL A;  3WV1 A;  1IAG A;  2Z2D A;  3EDZ A;  3N2U A;  3ZXH A;  4XM8 A;  1B8Y A;  4L6T A;  5I4O A;  2HU6 A;  4L63 A;  4H49 A;  1Q3A A;  4Q1L A;  3WV3 A;  3SHI A;  3K7L A;  1BQO A;  1DTH A;  1QIC A;  2AIG P;  3DPF A;  5H8X A;  2MLR A;  1ND1 A;  3G5C A;  3DSL A;  1QJJ A;  2WO9 A;  2E3X A;  1QIA A;  4JPA A;  4WKI A;  5D2B A;  1GO7 P;  3P1V A;  1Y8J A;  4H2E A;  1HFC A;  1IAA A;  1O0Q A;  1SU3 A;  3LUM A;  1SRP A;  4H82 A;  4JIJ A;  4AIG A;  3CKI A;  2RJP A;  1ZXV A;  1D7X A;  2OW9 A;  2X7M A;  1I73 A;  1MMP A;  1CXV A;  4L19 A;  2DW0 A;  4PKS A;  2Y6D A;  1GKD A;  4XCT A;  3RTS A;  2J83 A;  1JAQ A;  4PKQ A;  3HY7 A;  4H76 A;  1HFS A;  2DW2 A;  1IAB A;  3KWV C;  4DF9 A;  3KMC A;  3LK8 A;  4I35 A;  3LUN A;  1JAO A;  3U1R A;  3TVC A;  3GBO A;  3OHO A;  830C A;  4GR0 A;  1UMS A;  3I7G A;  2W14 A;  2DDF A;  3NX7 A;  1CAQ A;  4J4M A;  1C8T A;  3TSK A;  1PWQ A;  4JQG A;  4PKT A;  1PWP A;  4HX3 A;  1O0T A;  1QJI A;  4XBH A;  5D7W A;  3LQ0 A;  5BOT A;  1UTT A;  4H3X A;  2XS3 A;  3F18 A;  1BUD A;  1YOU A;  3V96 B;  2ERQ A;  3WV2 A;  3VTG A;  2W13 A;  1I1I P;  2OVX A;  2L0R A;  1L6J A;  2MZH A;  4A7B A;  3LJZ A;  1XFZ A;  1SLN A;  2OW0 A;  3Q2G A;  4WK7 A;  4WF6 A;  4H1Q A;  5JMY A;  3F16 A;  4R3V A;  3LJT A;  2OI0 A;  3P24 A;  3EDH A;  1USN A;  4PKV A;  2MLS A;  1R55 A;  2V4B A;  2E2D A;  2FV5 A;  2XS4 A;  3HBU P;  1HOV A;  1RM8 A;  2AYK A;  4AXQ A;  2YIG A;  3TS4 A;  1MMQ A;  2K9C A;  1FBL A;  1K7G A;  1IAD A;  1G12 A;  2RJQ A;  4ILW D;  1J7N A;  1KUH A;  4WZV A;  1SAT A;  1GE6 A;  1JIW P;  2OY4 A;  2WOA A;  3B8Z A;  4I03 A;  2DW1 A;  3LMC A;  1HTD A;  3O2X A;  1YCM A;  1Y93 A;  1KBC A;  1G4K A;  1GXD A;  4JA1 A;  1MNC A;  3KEC A;  3DL1 A;  2JT5 A;  1H71 P;  3HB2 P;  1XFX A;  1R1J A;  1G05 A;  1CGE A;  3LIR A;  3DNG A;  2CLT A;  2W12 A;  2CKI A;  3I7I A;  1C7K A;  4FVL A;  1BQQ M;  3KEK A;  1PWV A;  2W0D A;  2QPJ A;  1OM8 A;  5L7F A;  1XUR A;  1BKC I;  1DMT A;  456C A;  2OW1 A;  3O64 A;  1D5J A;  5D3C A;  1OS9 A;  2ERP A;  1HV5 A;  3LIL A;  3F1A A;  2OW2 A;  1UMT A;  1BIW A;  4ZR5 A;  1AKL A;  4EFS A;  5I43 A;  1CIZ A;  1IAC A;  3HBV P;  1XFW A;  1AF0 A;  1KAP P;  4FU4 A;  4G9L A;  1OO9 A;  1JKY A;  3KHI A;  3TT4 A;  4FXY P;  1BKC A;  2PJT A;  3B2Z A;  2X3B A;  1JAN A;  1S4B P;  1PWU A;  1C3I A;  1KUG A;  2D1N A;  1WNI A;  1QUA A;  2POJ A;  3HYG A;  3OHL A;  4IN9 A;  2X3C A;  1K7I A;  1CGL A;  5B5O A;  1R1H A;  2W15 A;  2JT6 A;  1MMR A;  3HDB A;  4AYK A;  3HDA P;  1ZS0 A;  1BSW A;  5I12 A;  3MA2 A;  2YB9 A;  5I2Z A;  5D1U A;  1AST A;  1G49 A;  4GWN A;  3F17 A;  1ATL A;  1XFY A;  5LAB A;  2OXW A;  2N8R A;  1SMP A;  4WKE A;  3BA0 A;  2K2G A;  1OMJ A;  4DD8 A;  1OM6 A;  2WO8 A;  4A3W A;  2JIH A;  2DDY A;  3ZUK A;  1D8M A;  1ROS A;  2JSD A;  2X3A A;  3AYU A;  1MMB A;  4QKZ A;  3EHX A;  5B5P A;  1FM1 A;  1FLS A;  5I0L A;  2A8H A;  1XFU A;  4CTH A;  3Q2H A;  1BUV M;  4GUY A;  4PKR A;  1GE5 A;  1A85 A;  3ELM A;  3EHY A;  1XFV A;  1XUC A;  4GF1 A;  4GR8 A;  1Z3J A;  1BKC E;  1EAK A;  2MZI A;  3DWB A;  2ERO A;  3LGP A;  2Y6C A;  1ZXC A;  1ZVX A;  4PKW A;  2USN A;  1UTZ A;  1PWW A;  3LKA A;  1A86 A;  4IUW A;  1JIZ A;  1ZTQ A;  1HY7 A;  1XUD A;  1G9K A;  1AYK A;  5I3M A;  2SRT A;  3LE9 A;  1YP1 A;  1JJ9 A;  3UVC A;  5D1T A;  3ZVS A;  3L0V A;  3LJG A;  1QIB A;  5BPA A;  4JP4 A;  3DPE A;  1KUI A;  4XM6 A;  1I76 A;  3AIG A;  3G42 A;  3K7N A;  5L79 A;  4H84 A;  966C A;  4HMA A;  4FXQ A;  5CZM A;  2O36 A;  1GE7 A;  1JH1 A;  1GKC A;  2J0T A;  5D1S A;  3F19 A;  1CGF A;  3B92 A;  3VI1 A;  1EB6 A;  4IJO A;  1KUF A;  1K7Q A;  1JAP A;  1GO8 P;  2D1O A;  1CK7 A;  1BZS A;  1D8F A;  1ZP5 A;  3EWJ A;  3AYK A;  5BOY A;  1R54 A;  4GR3 A;  2I47 A;  3F15 A;  5CXA A;  1Y0V A;  4PKU A;  1KUK A;  3KRY A;  2OXZ A;  2OZR A;  1CQR A;  4AUO A;  3EDI A;  3RTT A;  3KME A;  2OVZ A;  1BM6 A;  4XM7 A;  1B3D A;  2MZE A;  1EUB A;  1OS2 A;  4H30 A;  1OM7 A;  3N2V A;  5CUH A;  1IAE A;  3L0T A;  2FV9 A;  1SLM A;  2OY2 A;  3HY9 A;  1UEA A;  2JNP A;  4GWM A;  4DV8 A;  3LIK A;  4DPE A;  3USN A;  3LEA A;  4G0D A;  3LQB A;  2OXU A;  2KRJ A;  1YQY A;  3KEJ A;  4GQL A;  3EDG A;  1RMZ A;  2O3E A; 
#chains in the Genus database with same CATH topology
 1JK3 A;  4ON1 A;  3E8R A;  1R1I A;  2TCL A;  3WV1 A;  1IAG A;  2Z2D A;  3EDZ A;  3N2U A;  3ZXH A;  4XM8 A;  1B8Y A;  4L6T A;  5I4O A;  2HU6 A;  4L63 A;  4H49 A;  1Q3A A;  4Q1L A;  1XAX A;  3WV3 A;  3SHI A;  3K7L A;  1BQO A;  1DTH A;  1QIC A;  2AIG P;  3DPF A;  5H8X A;  2MLR A;  1ND1 A;  3G5C A;  3DSL A;  1QJJ A;  2WO9 A;  2E3X A;  1QIA A;  4JPA A;  4WKI A;  5D2B A;  1GO7 P;  3P1V A;  1Y8J A;  4H2E A;  1HFC A;  1IAA A;  1O0Q A;  1SU3 A;  3LUM A;  1SRP A;  4H82 A;  4JIJ A;  4AIG A;  3CKI A;  2RJP A;  1ZXV A;  1D7X A;  2OW9 A;  2X7M A;  1I73 A;  1MMP A;  1CXV A;  4L19 A;  2DW0 A;  4PKS A;  2Y6D A;  1GKD A;  4XCT A;  3RTS A;  2J83 A;  1JAQ A;  4PKQ A;  3HY7 A;  4H76 A;  1HFS A;  2DW2 A;  1IAB A;  3KWV C;  4DF9 A;  3KMC A;  3LK8 A;  4I35 A;  3LUN A;  1JAO A;  3U1R A;  3TVC A;  3GBO A;  3OHO A;  830C A;  4GR0 A;  1UMS A;  3I7G A;  2W14 A;  2DDF A;  3NX7 A;  1CAQ A;  4J4M A;  1C8T A;  3TSK A;  1PWQ A;  4JQG A;  4PKT A;  1PWP A;  4HX3 A;  1O0T A;  1QJI A;  4XBH A;  5D7W A;  3LQ0 A;  5BOT A;  1UTT A;  4H3X A;  2XS3 A;  3F18 A;  1BUD A;  1YOU A;  3V96 B;  2ERQ A;  3WV2 A;  3VTG A;  2W13 A;  1I1I P;  2OVX A;  2L0R A;  1L6J A;  2MZH A;  4A7B A;  3LJZ A;  1XFZ A;  1SLN A;  2OW0 A;  3Q2G A;  4WK7 A;  4WF6 A;  4H1Q A;  5JMY A;  3F16 A;  4R3V A;  3LJT A;  2OI0 A;  3P24 A;  3EDH A;  1USN A;  4PKV A;  2MLS A;  1R55 A;  2V4B A;  2E2D A;  2FV5 A;  2XS4 A;  3HBU P;  1HOV A;  1RM8 A;  2AYK A;  4AXQ A;  2YIG A;  3TS4 A;  1MMQ A;  2K9C A;  1FBL A;  1K7G A;  1IAD A;  1G12 A;  2RJQ A;  4ILW D;  1J7N A;  1KUH A;  4WZV A;  1OZ9 A;  1SAT A;  1GE6 A;  1JIW P;  2OY4 A;  2WOA A;  3B8Z A;  3DTI A;  4I03 A;  2DW1 A;  3LMC A;  1HTD A;  3O2X A;  1YCM A;  1Y93 A;  1KBC A;  1G4K A;  1GXD A;  4JA1 A;  1MNC A;  3KEC A;  3DL1 A;  2JT5 A;  1H71 P;  3HB2 P;  1XFX A;  1R1J A;  1G05 A;  1CGE A;  3LIR A;  3DNG A;  2CLT A;  2W12 A;  2CKI A;  3I7I A;  1C7K A;  4FVL A;  1BQQ M;  3KEK A;  1PWV A;  2W0D A;  2YUF A;  2QPJ A;  1OM8 A;  5L7F A;  1XUR A;  1BKC I;  1DMT A;  3DTE A;  456C A;  2OW1 A;  3O64 A;  1D5J A;  5D3C A;  1OS9 A;  2ERP A;  1HV5 A;  3LIL A;  3F1A A;  2OW2 A;  1UMT A;  1BIW A;  4ZR5 A;  1AKL A;  4EFS A;  5I43 A;  1CIZ A;  1IAC A;  3HBV P;  1XFW A;  1AF0 A;  1KAP P;  4FU4 A;  4G9L A;  1OO9 A;  1JKY A;  3KHI A;  3TT4 A;  4FXY P;  1BKC A;  2PJT A;  3B2Z A;  2X3B A;  1JAN A;  1S4B P;  1PWU A;  1C3I A;  1KUG A;  2D1N A;  1WNI A;  1QUA A;  2POJ A;  3HYG A;  3OHL A;  4IN9 A;  2X3C A;  1K7I A;  1CGL A;  4L7A A;  5B5O A;  3DTK A;  1R1H A;  2W15 A;  2JT6 A;  1MMR A;  3HDB A;  4AYK A;  3HDA P;  1ZS0 A;  1XM5 A;  1BSW A;  5I12 A;  3MA2 A;  2YB9 A;  5I2Z A;  5D1U A;  1AST A;  1G49 A;  4GWN A;  3F17 A;  1ATL A;  1XFY A;  5LAB A;  2OXW A;  2N8R A;  1SMP A;  4WKE A;  3BA0 A;  2K2G A;  1OMJ A;  4DD8 A;  1OM6 A;  2WO8 A;  4A3W A;  2JIH A;  2DDY A;  3ZUK A;  1D8M A;  1ROS A;  2JSD A;  2X3A A;  3AYU A;  1MMB A;  4QKZ A;  3EHX A;  5B5P A;  1FM1 A;  1FLS A;  5I0L A;  2A8H A;  1XFU A;  4CTH A;  3Q2H A;  1BUV M;  4GUY A;  4PKR A;  1GE5 A;  1A85 A;  3ELM A;  3EHY A;  1XFV A;  1XUC A;  4GF1 A;  4GR8 A;  1Z3J A;  1BKC E;  1EAK A;  2MZI A;  3DWB A;  2ERO A;  3LGP A;  2Y6C A;  1ZXC A;  1ZVX A;  4PKW A;  2USN A;  1UTZ A;  1PWW A;  1TVI A;  3LKA A;  1A86 A;  4IUW A;  1JIZ A;  1ZTQ A;  1HY7 A;  1XUD A;  1G9K A;  1AYK A;  5I3M A;  2SRT A;  3LE9 A;  1YP1 A;  1JJ9 A;  3UVC A;  5D1T A;  3ZVS A;  3L0V A;  3LJG A;  1QIB A;  5BPA A;  4JP4 A;  3DPE A;  1KUI A;  4XM6 A;  1I76 A;  3AIG A;  3G42 A;  3K7N A;  5L79 A;  4H84 A;  966C A;  4HMA A;  4FXQ A;  5CZM A;  2O36 A;  1GE7 A;  1JH1 A;  1GKC A;  2J0T A;  5D1S A;  3F19 A;  1CGF A;  3B92 A;  3VI1 A;  1EB6 A;  4IJO A;  1KUF A;  1K7Q A;  1JAP A;  1GO8 P;  2D1O A;  1CK7 A;  1BZS A;  1D8F A;  1ZP5 A;  3EWJ A;  3AYK A;  5BOY A;  1R54 A;  4GR3 A;  2I47 A;  3F15 A;  5CXA A;  1Y0V A;  4PKU A;  1KUK A;  3KRY A;  2OXZ A;  2OZR A;  1CQR A;  4AUO A;  3EDI A;  3RTT A;  3KME A;  2OVZ A;  1BM6 A;  4XM7 A;  1B3D A;  2MZE A;  1EUB A;  1OS2 A;  4H30 A;  1OM7 A;  3N2V A;  5CUH A;  1IAE A;  3L0T A;  2FV9 A;  1SLM A;  2OY2 A;  3HY9 A;  1UEA A;  2JNP A;  4GWM A;  4DV8 A;  3LIK A;  4DPE A;  3USN A;  3LEA A;  4G0D A;  3LQB A;  2OXU A;  2KRJ A;  1YQY A;  3KEJ A;  4GQL A;  3EDG A;  1RMZ A;  2O3E A; 
#chains in the Genus database with same CATH homology
 1JK3 A;  4ON1 A;  3E8R A;  1R1I A;  2TCL A;  3WV1 A;  1IAG A;  2Z2D A;  3EDZ A;  3N2U A;  3ZXH A;  4XM8 A;  1B8Y A;  4L6T A;  5I4O A;  2HU6 A;  4L63 A;  4H49 A;  1Q3A A;  4Q1L A;  3WV3 A;  3SHI A;  3K7L A;  1BQO A;  1DTH A;  1QIC A;  2AIG P;  3DPF A;  5H8X A;  2MLR A;  1ND1 A;  3G5C A;  3DSL A;  1QJJ A;  2WO9 A;  2E3X A;  1QIA A;  4JPA A;  4WKI A;  5D2B A;  1GO7 P;  3P1V A;  1Y8J A;  4H2E A;  1HFC A;  1IAA A;  1O0Q A;  1SU3 A;  3LUM A;  1SRP A;  4H82 A;  4JIJ A;  4AIG A;  3CKI A;  2RJP A;  1ZXV A;  1D7X A;  2OW9 A;  2X7M A;  1I73 A;  1MMP A;  1CXV A;  4L19 A;  2DW0 A;  4PKS A;  2Y6D A;  1GKD A;  4XCT A;  3RTS A;  2J83 A;  1JAQ A;  4PKQ A;  3HY7 A;  4H76 A;  1HFS A;  2DW2 A;  1IAB A;  3KWV C;  4DF9 A;  3KMC A;  3LK8 A;  4I35 A;  3LUN A;  1JAO A;  3U1R A;  3TVC A;  3GBO A;  3OHO A;  830C A;  4GR0 A;  1UMS A;  3I7G A;  2W14 A;  2DDF A;  3NX7 A;  1CAQ A;  4J4M A;  1C8T A;  3TSK A;  1PWQ A;  4JQG A;  4PKT A;  1PWP A;  4HX3 A;  1O0T A;  1QJI A;  4XBH A;  5D7W A;  3LQ0 A;  5BOT A;  1UTT A;  4H3X A;  2XS3 A;  3F18 A;  1BUD A;  1YOU A;  3V96 B;  2ERQ A;  3WV2 A;  3VTG A;  2W13 A;  1I1I P;  2OVX A;  2L0R A;  1L6J A;  2MZH A;  4A7B A;  3LJZ A;  1XFZ A;  1SLN A;  2OW0 A;  3Q2G A;  4WK7 A;  4WF6 A;  4H1Q A;  5JMY A;  3F16 A;  4R3V A;  3LJT A;  2OI0 A;  3P24 A;  3EDH A;  1USN A;  4PKV A;  2MLS A;  1R55 A;  2V4B A;  2E2D A;  2FV5 A;  2XS4 A;  3HBU P;  1HOV A;  1RM8 A;  2AYK A;  4AXQ A;  2YIG A;  3TS4 A;  1MMQ A;  2K9C A;  1FBL A;  1K7G A;  1IAD A;  1G12 A;  2RJQ A;  4ILW D;  1J7N A;  1KUH A;  4WZV A;  1SAT A;  1GE6 A;  1JIW P;  2OY4 A;  2WOA A;  3B8Z A;  3DTI A;  4I03 A;  2DW1 A;  3LMC A;  1HTD A;  3O2X A;  1YCM A;  1Y93 A;  1KBC A;  1G4K A;  1GXD A;  4JA1 A;  1MNC A;  3KEC A;  3DL1 A;  2JT5 A;  1H71 P;  3HB2 P;  1XFX A;  1R1J A;  1G05 A;  1CGE A;  3LIR A;  3DNG A;  2CLT A;  2W12 A;  2CKI A;  3I7I A;  1C7K A;  4FVL A;  1BQQ M;  3KEK A;  1PWV A;  2W0D A;  2YUF A;  2QPJ A;  1OM8 A;  5L7F A;  1XUR A;  1BKC I;  1DMT A;  3DTE A;  456C A;  2OW1 A;  3O64 A;  1D5J A;  5D3C A;  1OS9 A;  2ERP A;  1HV5 A;  3LIL A;  3F1A A;  2OW2 A;  1UMT A;  1BIW A;  4ZR5 A;  1AKL A;  4EFS A;  5I43 A;  1CIZ A;  1IAC A;  3HBV P;  1XFW A;  1AF0 A;  1KAP P;  4FU4 A;  4G9L A;  1OO9 A;  1JKY A;  3KHI A;  3TT4 A;  4FXY P;  1BKC A;  2PJT A;  3B2Z A;  2X3B A;  1JAN A;  1S4B P;  1PWU A;  1C3I A;  1KUG A;  2D1N A;  1WNI A;  1QUA A;  2POJ A;  3HYG A;  3OHL A;  4IN9 A;  2X3C A;  1K7I A;  1CGL A;  4L7A A;  5B5O A;  3DTK A;  1R1H A;  2W15 A;  2JT6 A;  1MMR A;  3HDB A;  4AYK A;  3HDA P;  1ZS0 A;  1BSW A;  5I12 A;  3MA2 A;  2YB9 A;  5I2Z A;  5D1U A;  1AST A;  1G49 A;  4GWN A;  3F17 A;  1ATL A;  1XFY A;  5LAB A;  2OXW A;  2N8R A;  1SMP A;  4WKE A;  3BA0 A;  2K2G A;  1OMJ A;  4DD8 A;  1OM6 A;  2WO8 A;  4A3W A;  2JIH A;  2DDY A;  3ZUK A;  1D8M A;  1ROS A;  2JSD A;  2X3A A;  3AYU A;  1MMB A;  4QKZ A;  3EHX A;  5B5P A;  1FM1 A;  1FLS A;  5I0L A;  2A8H A;  1XFU A;  4CTH A;  3Q2H A;  1BUV M;  4GUY A;  4PKR A;  1GE5 A;  1A85 A;  3ELM A;  3EHY A;  1XFV A;  1XUC A;  4GF1 A;  4GR8 A;  1Z3J A;  1BKC E;  1EAK A;  2MZI A;  3DWB A;  2ERO A;  3LGP A;  2Y6C A;  1ZXC A;  1ZVX A;  4PKW A;  2USN A;  1UTZ A;  1PWW A;  3LKA A;  1A86 A;  4IUW A;  1JIZ A;  1ZTQ A;  1HY7 A;  1XUD A;  1G9K A;  1AYK A;  5I3M A;  2SRT A;  3LE9 A;  1YP1 A;  1JJ9 A;  3UVC A;  5D1T A;  3ZVS A;  3L0V A;  3LJG A;  1QIB A;  5BPA A;  4JP4 A;  3DPE A;  1KUI A;  4XM6 A;  1I76 A;  3AIG A;  3G42 A;  3K7N A;  5L79 A;  4H84 A;  966C A;  4HMA A;  4FXQ A;  5CZM A;  2O36 A;  1GE7 A;  1JH1 A;  1GKC A;  2J0T A;  5D1S A;  3F19 A;  1CGF A;  3B92 A;  3VI1 A;  1EB6 A;  4IJO A;  1KUF A;  1K7Q A;  1JAP A;  1GO8 P;  2D1O A;  1CK7 A;  1BZS A;  1D8F A;  1ZP5 A;  3EWJ A;  3AYK A;  5BOY A;  1R54 A;  4GR3 A;  2I47 A;  3F15 A;  5CXA A;  1Y0V A;  4PKU A;  1KUK A;  3KRY A;  2OXZ A;  2OZR A;  1CQR A;  4AUO A;  3EDI A;  3RTT A;  3KME A;  2OVZ A;  1BM6 A;  4XM7 A;  1B3D A;  2MZE A;  1EUB A;  1OS2 A;  4H30 A;  1OM7 A;  3N2V A;  5CUH A;  1IAE A;  3L0T A;  2FV9 A;  1SLM A;  2OY2 A;  3HY9 A;  1UEA A;  2JNP A;  4GWM A;  4DV8 A;  3LIK A;  4DPE A;  3USN A;  3LEA A;  4G0D A;  3LQB A;  2OXU A;  2KRJ A;  1YQY A;  3KEJ A;  4GQL A;  3EDG A;  1RMZ A;  2O3E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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