1CIZA

X-ray structure of human stromelysin catalytic domain complexes with non-peptide inhibitors: implication for inhibitor selectivity
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
168
structure length
168
Chain Sequence
FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.
pubmed rcsb
molecule tags Metalloproteinase
source organism Homo sapiens
molecule keywords PROTEIN (STROMELYSIN-1)
total genus 47
structure length 168
sequence length 168
ec nomenclature ec 3.4.24.17: Stromelysin 1.
pdb deposition date 1999-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1cizA00
3LGPA 3LUMA 2DW0A 1JKYA 2L0RA 3LQ0A 4XM6A 1PWPA 1CIZA 4DD8A 1QIAA 2O36A 4CTHA 1ZXVA 4Q1LA 3DL1A 3ZXHA 1OM6A 2X3AA 1FM1A 1XUCA 4H30A 2X3CA 1ZP5A 3LE9A 2DDFA 3HB2P 1KAPP 1AKLA 1IAAA 3L0VA 1BIWA 2JT6A 1UEAA 1IAGA 1G05A 2OXUA 1GE5A 4PKRA 4J4MA 4G9LA 5LABA 1EUBA 4FXYP 830CA 1HV5A 1CGLA 4PKSA 2YB9A 3LQBA 2AYKA 4ILWD 4DF9A 1O0QA 4FVLA 1PWVA 1XUDA 1YOUA 4IUWA 4QKZA 4ZR5A 1ZXCA 3LEAA 1GKCA 3DNGA 2MLSA 1XFVA 1GO8P 2MLRA 2QPJA 4DPEA 2E3XA 3WV2A 2O3EA 3WV1A 1FBLA 2DW2A 1KUFA 2FV5A 2V4BA 4H3XA 1JH1A 1I73A 1ZVXA 5D7WA 1MNCA 1HFCA 1YQYA 5D1UA 4JPAA 1ROSA 3KRYA 5BOTA 4WKIA 3O64A 1G9KA 3VTGA 1XFUA 3DWBA 3V96B 3KEJA 3CKIA 1HY7A 1R1HA 1PWWA 2XS4A 4PKUA 1G49A 1A86A 3KMEA 3HDBA 1ASTA 1EB6A 4PKWA 5L79A 3VI1A 1CGEA 5I0LA 2YIGA 4AUOA 1SLMA 1RMZA 2TCLA 4GR8A 1S4BP 2OW2A 3EDIA 2J0TA 3KWVC 5I2ZA 4G0DA 2OXWA 3B8ZA 1H71P 1YCMA 1IAEA 4AYKA 1JAPA 3ELMA 1ATLA 4I35A 4A7BA 1KUKA 3WV3A 2MZEA 5H8XA 1BM6A 2RJQA 1XFZA 3B2ZA 4JQGA 1PWQA 3AYKA 1HTDA 5CXAA 1AF0A 1KUGA 2X7MA 1GE7A 3MA2A 4H84A 1Y0VA 2FV9A 1D8FA 1D5JA 1XFXA 2K9CA 4GWNA 3TS4A 3LJGA 3LMCA 2CLTA 3DPEA 1K7IA 966CA 3E8RA 1FLSA 2OW0A 2EROA 1DTHA 1YP1A 1BZSA 3F16A 3I7GA 3RTSA 3AYUA 3EHXA 2N8RA 3HY9A 1BUVM 3EDHA 1I76A 1SMPA 4A3WA 3U1RA 3KHIA 1QIBA 3LJZA 2A8HA 1OMJA 4XM7A 3DSLA 2Y6CA 4IJOA 3HBUP 3GBOA 3BA0A 1Q3AA 4HX3A 3F18A 1JIWP 1CQRA 1UTTA 4ON1A 5I4OA 1KBCA 3LUNA 1D7XA 4FXQA 1MMQA 2MZIA 3G5CA 1OS2A 2ERPA 2OY4A 4L63A 2OY2A 1MMPA 2I47A 1Z3JA 5JMYA 2X3BA 3SHIA 4AXQA 3LK8A 3OHLA 1WNIA 4AIGA 5I43A 3ZVSA 2OVXA 1IADA 4GF1A 2JIHA 3TT4A 4L19A 2OZRA 4JP4A 3I7IA 1ZTQA 1C7KA 4IN9A 2JT5A 1J7NA 1A85A 5D1TA 1MMRA 4PKVA 2DW1A 4WZVA 3LJTA 1ZS0A 3EWJA 1B8YA 3P1VA 2POJA 1JIZA 1C8TA 1KUIA 1SLNA 5D3CA 4L6TA 2AIGP 1CGFA 2DDYA 1QJJA 4HMAA 2W13A 3UVCA 1SU3A 3LIRA 4GR3A 1RM8A 2K2GA 1UTZA 1KUHA 1QICA 4JA1A 4H49A 3NX7A 1O0TA 1JK3A 3EDZA 3LKAA 1G4KA 2PJTA 2XS3A 1EAKA 2ERQA 3B92A 4GUYA 1K7QA 1JAQA 1XURA 3Q2GA 2WOAA 5D1SA 3RTTA 3HBVP 3N2VA 1HFSA 1SATA 1XFWA 1DMTA 2Z2DA 1IACA 1JAOA 1XFYA 1R1JA 3EDGA 4XBHA 3F15A 1QJIA 2W0DA 4DV8A 4WK7A 2JNPA 4GR0A 1GE6A 3F1AA 3DPFA 4GQLA 2JSDA 1BSWA 1BKCA 4H76A 3K7NA 4JIJA 3TSKA 2KRJA 1K7GA 2OXZA 1OM7A 3TVCA 3F17A 1BUDA 1AYKA 5B5PA 2W14A 4XCTA 5B5OA 1I1IP 3USNA 1BQQM 2OI0A 4I03A 5CZMA 3G42A 2E2DA 1R54A 1D8MA 1Y93A 5CUHA 1SRPA 5BOYA 3HDAP 5L7FA 4XM8A 1CAQA 4H82A 3LILA 1C3IA 2USNA 2D1OA 1OS9A 2D1NA 3HYGA 2OW1A 4PKQA 456CA 1L6JA 3OHOA 1OM8A 3P24A 1JANA 3KEKA 3O2XA 5D2BA 1USNA 3Q2HA 1BQOA 1IABA 1GXDA 4PKTA 2CKIA 2Y6DA 2OVZA 1BKCI 3HY7A 1UMSA 1QUAA 1ND1A 3AIGA 3EHYA 4H1QA 1R55A 4WKEA 1PWUA 1R1IA 1JJ9A 1HOVA 5I12A 1BKCE 1Y8JA 1B3DA 4GWMA 3KMCA 2OW9A 2SRTA 2MZHA 3K7LA 1GO7P 3LIKA 2HU6A 1CK7A 5I3MA 2RJPA 5BPAA 3KECA 3ZUKA 4WF6A 1OO9A 4FU4A 2W12A 4H2EA 1CXVA 2W15A 1MMBA 3L0TA 4R3VA 2J83A 2WO8A 2WO9A 1G12A 4EFSA 3N2UA 1UMTA 1GKDA 3F19A
chains in the Genus database with same CATH superfamily
3LGPA 3LUMA 2DW0A 1JKYA 2L0RA 3LQ0A 4XM6A 1PWPA 1CIZA 4DD8A 1QIAA 2O36A 4CTHA 1ZXVA 4Q1LA 3DL1A 3ZXHA 1OM6A 2X3AA 1FM1A 1XUCA 4H30A 2X3CA 1ZP5A 3LE9A 2DDFA 3HB2P 1KAPP 1AKLA 1IAAA 3L0VA 1BIWA 2JT6A 1UEAA 1IAGA 1G05A 2OXUA 1GE5A 4PKRA 4J4MA 4G9LA 5LABA 1EUBA 4FXYP 830CA 1HV5A 1CGLA 4PKSA 2YB9A 3LQBA 2AYKA 4ILWD 4DF9A 1O0QA 4FVLA 1PWVA 1XUDA 1YOUA 4IUWA 4QKZA 4ZR5A 1ZXCA 3LEAA 1GKCA 3DNGA 2MLSA 1XFVA 1GO8P 2MLRA 2QPJA 4DPEA 2E3XA 3WV2A 2O3EA 3WV1A 1FBLA 2DW2A 1KUFA 2FV5A 2V4BA 4H3XA 1JH1A 1I73A 1ZVXA 5D7WA 1MNCA 1HFCA 1YQYA 5D1UA 4JPAA 1ROSA 3KRYA 5BOTA 4WKIA 3O64A 1G9KA 3VTGA 1XFUA 3DWBA 3V96B 3KEJA 3CKIA 1HY7A 1R1HA 1PWWA 2XS4A 4PKUA 1G49A 1A86A 3KMEA 3HDBA 1ASTA 1EB6A 4PKWA 5L79A 3VI1A 1CGEA 5I0LA 2YIGA 4AUOA 1SLMA 1RMZA 2TCLA 4GR8A 1S4BP 2OW2A 3EDIA 2J0TA 3KWVC 5I2ZA 4G0DA 2OXWA 3B8ZA 1H71P 1YCMA 1IAEA 4AYKA 1JAPA 3ELMA 1ATLA 4I35A 4A7BA 1KUKA 3WV3A 2MZEA 5H8XA 1BM6A 2RJQA 1XFZA 3B2ZA 4JQGA 1PWQA 3AYKA 1HTDA 5CXAA 1AF0A 1KUGA 2X7MA 1GE7A 3MA2A 4H84A 1Y0VA 2FV9A 1D8FA 1D5JA 1XFXA 2K9CA 4GWNA 3TS4A 3DTKA 3LJGA 3LMCA 2CLTA 3DPEA 1K7IA 966CA 3E8RA 1FLSA 2OW0A 2EROA 1DTHA 1YP1A 1BZSA 2YUFA 3F16A 3I7GA 3RTSA 3AYUA 3EHXA 2N8RA 1XM5A 3HY9A 1BUVM 3EDHA 1I76A 1SMPA 4A3WA 3U1RA 3KHIA 1QIBA 3LJZA 2A8HA 1OMJA 4XM7A 3DSLA 2Y6CA 4IJOA 3HBUP 3GBOA 3BA0A 1Q3AA 4HX3A 3F18A 1JIWP 1XAXA 1CQRA 1UTTA 4ON1A 5I4OA 1KBCA 3LUNA 1D7XA 4FXQA 1MMQA 2MZIA 3G5CA 1OS2A 2ERPA 2OY4A 4L63A 2OY2A 1MMPA 2I47A 1Z3JA 5JMYA 2X3BA 3SHIA 4AXQA 3LK8A 3OHLA 1WNIA 4AIGA 5I43A 3ZVSA 2OVXA 1IADA 4GF1A 2JIHA 3TT4A 4L19A 2OZRA 4JP4A 3I7IA 1ZTQA 1C7KA 4IN9A 2JT5A 1J7NA 1A85A 5D1TA 1MMRA 4PKVA 2DW1A 4WZVA 3LJTA 1ZS0A 3EWJA 1B8YA 3P1VA 2POJA 1JIZA 1C8TA 3DTEA 1KUIA 1SLNA 5D3CA 4L6TA 2AIGP 1CGFA 2DDYA 1QJJA 4HMAA 2W13A 3UVCA 1SU3A 3LIRA 4GR3A 1RM8A 2K2GA 1UTZA 1KUHA 1TVIA 1QICA 4JA1A 4H49A 3NX7A 1O0TA 1JK3A 3EDZA 3LKAA 1G4KA 2PJTA 2XS3A 1EAKA 2ERQA 3B92A 4GUYA 1K7QA 1JAQA 1XURA 3Q2GA 2WOAA 5D1SA 3RTTA 3HBVP 3N2VA 1HFSA 1SATA 1XFWA 1DMTA 2Z2DA 1IACA 1JAOA 1XFYA 1R1JA 3EDGA 4XBHA 3F15A 1QJIA 2W0DA 4DV8A 4WK7A 2JNPA 4GR0A 1GE6A 3F1AA 3DPFA 4GQLA 2JSDA 1BSWA 1BKCA 4H76A 3K7NA 4JIJA 3TSKA 2KRJA 1K7GA 2OXZA 1OM7A 3TVCA 3F17A 1BUDA 1AYKA 5B5PA 2W14A 4XCTA 5B5OA 1I1IP 3USNA 1BQQM 2OI0A 4I03A 5CZMA 3G42A 2E2DA 1R54A 1D8MA 1Y93A 5CUHA 1SRPA 5BOYA 3HDAP 5L7FA 4XM8A 1CAQA 4H82A 3LILA 1C3IA 2USNA 2D1OA 1OS9A 2D1NA 3HYGA 2OW1A 4PKQA 456CA 1L6JA 3OHOA 1OM8A 3P24A 1JANA 3KEKA 3O2XA 5D2BA 1USNA 3Q2HA 1BQOA 1IABA 1GXDA 4PKTA 2CKIA 2Y6DA 2OVZA 1BKCI 3HY7A 1UMSA 4L7AA 1QUAA 1ND1A 3AIGA 3EHYA 4H1QA 1R55A 4WKEA 1PWUA 1R1IA 1JJ9A 1HOVA 5I12A 1BKCE 1Y8JA 1B3DA 4GWMA 3KMCA 2OW9A 2SRTA 2MZHA 3K7LA 1GO7P 3LIKA 2HU6A 1CK7A 5I3MA 1OZ9A 2RJPA 5BPAA 3KECA 3ZUKA 4WF6A 3DTIA 1OO9A 4FU4A 2W12A 4H2EA 1CXVA 2W15A 1MMBA 3L0TA 4R3VA 2J83A 2WO8A 2WO9A 1G12A 4EFSA 3N2UA 1UMTA 1GKDA 3F19A
chains in the Genus database with same CATH topology
3LGPA 3LUMA 2DW0A 1JKYA 2L0RA 3LQ0A 4XM6A 1PWPA 1CIZA 4DD8A 1QIAA 2O36A 4CTHA 1ZXVA 4Q1LA 3DL1A 3ZXHA 1OM6A 2X3AA 1FM1A 1XUCA 4H30A 2X3CA 1ZP5A 3LE9A 2DDFA 3HB2P 1KAPP 1AKLA 1IAAA 3L0VA 1BIWA 2JT6A 1UEAA 1IAGA 1G05A 2OXUA 1GE5A 4PKRA 4J4MA 4G9LA 5LABA 1EUBA 4FXYP 830CA 1HV5A 1CGLA 4PKSA 2YB9A 3LQBA 2AYKA 4ILWD 4DF9A 1O0QA 4FVLA 1PWVA 1XUDA 1YOUA 4IUWA 4QKZA 4ZR5A 1ZXCA 3LEAA 1GKCA 3DNGA 2MLSA 1XFVA 1GO8P 2MLRA 2QPJA 4DPEA 2E3XA 3WV2A 2O3EA 3WV1A 1FBLA 2DW2A 1KUFA 2FV5A 2V4BA 4H3XA 1JH1A 1I73A 1ZVXA 5D7WA 1MNCA 1HFCA 1YQYA 5D1UA 4JPAA 1ROSA 3KRYA 5BOTA 4WKIA 3O64A 1G9KA 3VTGA 1XFUA 3DWBA 3V96B 3KEJA 3CKIA 1HY7A 1R1HA 1PWWA 2XS4A 4PKUA 1G49A 1A86A 3KMEA 3HDBA 1ASTA 1EB6A 4PKWA 5L79A 3VI1A 1CGEA 5I0LA 2YIGA 4AUOA 1SLMA 1RMZA 2TCLA 4GR8A 1S4BP 2OW2A 3EDIA 2J0TA 3KWVC 5I2ZA 4G0DA 2OXWA 3B8ZA 1H71P 1YCMA 1IAEA 4AYKA 1JAPA 3ELMA 1ATLA 4I35A 4A7BA 1KUKA 3WV3A 2MZEA 5H8XA 1BM6A 2RJQA 1XFZA 3B2ZA 4JQGA 1PWQA 3AYKA 1HTDA 5CXAA 1AF0A 1KUGA 2X7MA 1GE7A 3MA2A 4H84A 1Y0VA 2FV9A 1D8FA 1D5JA 1XFXA 2K9CA 4GWNA 3TS4A 3DTKA 3LJGA 3LMCA 2CLTA 3DPEA 1K7IA 966CA 3E8RA 1FLSA 2OW0A 2EROA 1DTHA 1YP1A 1BZSA 2YUFA 3F16A 3I7GA 3RTSA 3AYUA 3EHXA 2N8RA 3HY9A 1BUVM 3EDHA 1I76A 1SMPA 4A3WA 3U1RA 3KHIA 1QIBA 3LJZA 2A8HA 1OMJA 4XM7A 3DSLA 2Y6CA 4IJOA 3HBUP 3GBOA 3BA0A 1Q3AA 4HX3A 3F18A 1JIWP 1CQRA 1UTTA 4ON1A 5I4OA 1KBCA 3LUNA 1D7XA 4FXQA 1MMQA 2MZIA 3G5CA 1OS2A 2ERPA 2OY4A 4L63A 2OY2A 1MMPA 2I47A 1Z3JA 5JMYA 2X3BA 3SHIA 4AXQA 3LK8A 3OHLA 1WNIA 4AIGA 5I43A 3ZVSA 2OVXA 1IADA 4GF1A 2JIHA 3TT4A 4L19A 2OZRA 4JP4A 3I7IA 1ZTQA 1C7KA 4IN9A 2JT5A 1J7NA 1A85A 5D1TA 1MMRA 4PKVA 2DW1A 4WZVA 3LJTA 1ZS0A 3EWJA 1B8YA 3P1VA 2POJA 1JIZA 1C8TA 3DTEA 1KUIA 1SLNA 5D3CA 4L6TA 2AIGP 1CGFA 2DDYA 1QJJA 4HMAA 2W13A 3UVCA 1SU3A 3LIRA 4GR3A 1RM8A 2K2GA 1UTZA 1KUHA 1QICA 4JA1A 4H49A 3NX7A 1O0TA 1JK3A 3EDZA 3LKAA 1G4KA 2PJTA 2XS3A 1EAKA 2ERQA 3B92A 4GUYA 1K7QA 1JAQA 1XURA 3Q2GA 2WOAA 5D1SA 3RTTA 3HBVP 3N2VA 1HFSA 1SATA 1XFWA 1DMTA 2Z2DA 1IACA 1JAOA 1XFYA 1R1JA 3EDGA 4XBHA 3F15A 1QJIA 2W0DA 4DV8A 4WK7A 2JNPA 4GR0A 1GE6A 3F1AA 3DPFA 4GQLA 2JSDA 1BSWA 1BKCA 4H76A 3K7NA 4JIJA 3TSKA 2KRJA 1K7GA 2OXZA 1OM7A 3TVCA 3F17A 1BUDA 1AYKA 5B5PA 2W14A 4XCTA 5B5OA 1I1IP 3USNA 1BQQM 2OI0A 4I03A 5CZMA 3G42A 2E2DA 1R54A 1D8MA 1Y93A 5CUHA 1SRPA 5BOYA 3HDAP 5L7FA 4XM8A 1CAQA 4H82A 3LILA 1C3IA 2USNA 2D1OA 1OS9A 2D1NA 3HYGA 2OW1A 4PKQA 456CA 1L6JA 3OHOA 1OM8A 3P24A 1JANA 3KEKA 3O2XA 5D2BA 1USNA 3Q2HA 1BQOA 1IABA 1GXDA 4PKTA 2CKIA 2Y6DA 2OVZA 1BKCI 3HY7A 1UMSA 4L7AA 1QUAA 1ND1A 3AIGA 3EHYA 4H1QA 1R55A 4WKEA 1PWUA 1R1IA 1JJ9A 1HOVA 5I12A 1BKCE 1Y8JA 1B3DA 4GWMA 3KMCA 2OW9A 2SRTA 2MZHA 3K7LA 1GO7P 3LIKA 2HU6A 1CK7A 5I3MA 2RJPA 5BPAA 3KECA 3ZUKA 4WF6A 3DTIA 1OO9A 4FU4A 2W12A 4H2EA 1CXVA 2W15A 1MMBA 3L0TA 4R3VA 2J83A 2WO8A 2WO9A 1G12A 4EFSA 3N2UA 1UMTA 1GKDA 3F19A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LGP A;  3LUM A;  2DW0 A;  1JKY A;  2L0R A;  3LQ0 A;  4XM6 A;  1PWP A;  1CIZ A;  4DD8 A;  1QIA A;  2O36 A;  4CTH A;  1ZXV A;  4Q1L A;  3DL1 A;  3ZXH A;  1OM6 A;  2X3A A;  1FM1 A;  1XUC A;  4H30 A;  2X3C A;  1ZP5 A;  3LE9 A;  2DDF A;  3HB2 P;  1KAP P;  1AKL A;  1IAA A;  3L0V A;  1BIW A;  2JT6 A;  1UEA A;  1IAG A;  1G05 A;  2OXU A;  1GE5 A;  4PKR A;  4J4M A;  4G9L A;  5LAB A;  1EUB A;  4FXY P;  830C A;  1HV5 A;  1CGL A;  4PKS A;  2YB9 A;  3LQB A;  2AYK A;  4ILW D;  4DF9 A;  1O0Q A;  4FVL A;  1PWV A;  1XUD A;  1YOU A;  4IUW A;  4QKZ A;  4ZR5 A;  1ZXC A;  3LEA A;  1GKC A;  3DNG A;  2MLS A;  1XFV A;  1GO8 P;  2MLR A;  2QPJ A;  4DPE A;  2E3X A;  3WV2 A;  2O3E A;  3WV1 A;  1FBL A;  2DW2 A;  1KUF A;  2FV5 A;  2V4B A;  4H3X A;  1JH1 A;  1I73 A;  1ZVX A;  5D7W A;  1MNC A;  1HFC A;  1YQY A;  5D1U A;  4JPA A;  1ROS A;  3KRY A;  5BOT A;  4WKI A;  3O64 A;  1G9K A;  3VTG A;  1XFU A;  3DWB A;  3V96 B;  3KEJ A;  3CKI A;  1HY7 A;  1R1H A;  1PWW A;  2XS4 A;  4PKU A;  1G49 A;  1A86 A;  3KME A;  3HDB A;  1AST A;  1EB6 A;  4PKW A;  5L79 A;  3VI1 A;  1CGE A;  5I0L A;  2YIG A;  4AUO A;  1SLM A;  1RMZ A;  2TCL A;  4GR8 A;  1S4B P;  2OW2 A;  3EDI A;  2J0T A;  3KWV C;  5I2Z A;  4G0D A;  2OXW A;  3B8Z A;  1H71 P;  1YCM A;  1IAE A;  4AYK A;  1JAP A;  3ELM A;  1ATL A;  4I35 A;  4A7B A;  1KUK A;  3WV3 A;  2MZE A;  5H8X A;  1BM6 A;  2RJQ A;  1XFZ A;  3B2Z A;  4JQG A;  1PWQ A;  3AYK A;  1HTD A;  5CXA A;  1AF0 A;  1KUG A;  2X7M A;  1GE7 A;  3MA2 A;  4H84 A;  1Y0V A;  2FV9 A;  1D8F A;  1D5J A;  1XFX A;  2K9C A;  4GWN A;  3TS4 A;  3LJG A;  3LMC A;  2CLT A;  3DPE A;  1K7I A;  966C A;  3E8R A;  1FLS A;  2OW0 A;  2ERO A;  1DTH A;  1YP1 A;  1BZS A;  3F16 A;  3I7G A;  3RTS A;  3AYU A;  3EHX A;  2N8R A;  3HY9 A;  1BUV M;  3EDH A;  1I76 A;  1SMP A;  4A3W A;  3U1R A;  3KHI A;  1QIB A;  3LJZ A;  2A8H A;  1OMJ A;  4XM7 A;  3DSL A;  2Y6C A;  4IJO A;  3HBU P;  3GBO A;  3BA0 A;  1Q3A A;  4HX3 A;  3F18 A;  1JIW P;  1CQR A;  1UTT A;  4ON1 A;  5I4O A;  1KBC A;  3LUN A;  1D7X A;  4FXQ A;  1MMQ A;  2MZI A;  3G5C A;  1OS2 A;  2ERP A;  2OY4 A;  4L63 A;  2OY2 A;  1MMP A;  2I47 A;  1Z3J A;  5JMY A;  2X3B A;  3SHI A;  4AXQ A;  3LK8 A;  3OHL A;  1WNI A;  4AIG A;  5I43 A;  3ZVS A;  2OVX A;  1IAD A;  4GF1 A;  2JIH A;  3TT4 A;  4L19 A;  2OZR A;  4JP4 A;  3I7I A;  1ZTQ A;  1C7K A;  4IN9 A;  2JT5 A;  1J7N A;  1A85 A;  5D1T A;  1MMR A;  4PKV A;  2DW1 A;  4WZV A;  3LJT A;  1ZS0 A;  3EWJ A;  1B8Y A;  3P1V A;  2POJ A;  1JIZ A;  1C8T A;  1KUI A;  1SLN A;  5D3C A;  4L6T A;  2AIG P;  1CGF A;  2DDY A;  1QJJ A;  4HMA A;  2W13 A;  3UVC A;  1SU3 A;  3LIR A;  4GR3 A;  1RM8 A;  2K2G A;  1UTZ A;  1KUH A;  1QIC A;  4JA1 A;  4H49 A;  3NX7 A;  1O0T A;  1JK3 A;  3EDZ A;  3LKA A;  1G4K A;  2PJT A;  2XS3 A;  1EAK A;  2ERQ A;  3B92 A;  4GUY A;  1K7Q A;  1JAQ A;  1XUR A;  3Q2G A;  2WOA A;  5D1S A;  3RTT A;  3HBV P;  3N2V A;  1HFS A;  1SAT A;  1XFW A;  1DMT A;  2Z2D A;  1IAC A;  1JAO A;  1XFY A;  1R1J A;  3EDG A;  4XBH A;  3F15 A;  1QJI A;  2W0D A;  4DV8 A;  4WK7 A;  2JNP A;  4GR0 A;  1GE6 A;  3F1A A;  3DPF A;  4GQL A;  2JSD A;  1BSW A;  1BKC A;  4H76 A;  3K7N A;  4JIJ A;  3TSK A;  2KRJ A;  1K7G A;  2OXZ A;  1OM7 A;  3TVC A;  3F17 A;  1BUD A;  1AYK A;  5B5P A;  2W14 A;  4XCT A;  5B5O A;  1I1I P;  3USN A;  1BQQ M;  2OI0 A;  4I03 A;  5CZM A;  3G42 A;  2E2D A;  1R54 A;  1D8M A;  1Y93 A;  5CUH A;  1SRP A;  5BOY A;  3HDA P;  5L7F A;  4XM8 A;  1CAQ A;  4H82 A;  3LIL A;  1C3I A;  2USN A;  2D1O A;  1OS9 A;  2D1N A;  3HYG A;  2OW1 A;  4PKQ A;  456C A;  1L6J A;  3OHO A;  1OM8 A;  3P24 A;  1JAN A;  3KEK A;  3O2X A;  5D2B A;  1USN A;  3Q2H A;  1BQO A;  1IAB A;  1GXD A;  4PKT A;  2CKI A;  2Y6D A;  2OVZ A;  1BKC I;  3HY7 A;  1UMS A;  1QUA A;  1ND1 A;  3AIG A;  3EHY A;  4H1Q A;  1R55 A;  4WKE A;  1PWU A;  1R1I A;  1JJ9 A;  1HOV A;  5I12 A;  1BKC E;  1Y8J A;  1B3D A;  4GWM A;  3KMC A;  2OW9 A;  2SRT A;  2MZH A;  3K7L A;  1GO7 P;  3LIK A;  2HU6 A;  1CK7 A;  5I3M A;  2RJP A;  5BPA A;  3KEC A;  3ZUK A;  4WF6 A;  1OO9 A;  4FU4 A;  2W12 A;  4H2E A;  1CXV A;  2W15 A;  1MMB A;  3L0T A;  4R3V A;  2J83 A;  2WO8 A;  2WO9 A;  1G12 A;  4EFS A;  3N2U A;  1UMT A;  1GKD A;  3F19 A; 
#chains in the Genus database with same CATH topology
 3LGP A;  3LUM A;  2DW0 A;  1JKY A;  2L0R A;  3LQ0 A;  4XM6 A;  1PWP A;  1CIZ A;  4DD8 A;  1QIA A;  2O36 A;  4CTH A;  1ZXV A;  4Q1L A;  3DL1 A;  3ZXH A;  1OM6 A;  2X3A A;  1FM1 A;  1XUC A;  4H30 A;  2X3C A;  1ZP5 A;  3LE9 A;  2DDF A;  3HB2 P;  1KAP P;  1AKL A;  1IAA A;  3L0V A;  1BIW A;  2JT6 A;  1UEA A;  1IAG A;  1G05 A;  2OXU A;  1GE5 A;  4PKR A;  4J4M A;  4G9L A;  5LAB A;  1EUB A;  4FXY P;  830C A;  1HV5 A;  1CGL A;  4PKS A;  2YB9 A;  3LQB A;  2AYK A;  4ILW D;  4DF9 A;  1O0Q A;  4FVL A;  1PWV A;  1XUD A;  1YOU A;  4IUW A;  4QKZ A;  4ZR5 A;  1ZXC A;  3LEA A;  1GKC A;  3DNG A;  2MLS A;  1XFV A;  1GO8 P;  2MLR A;  2QPJ A;  4DPE A;  2E3X A;  3WV2 A;  2O3E A;  3WV1 A;  1FBL A;  2DW2 A;  1KUF A;  2FV5 A;  2V4B A;  4H3X A;  1JH1 A;  1I73 A;  1ZVX A;  5D7W A;  1MNC A;  1HFC A;  1YQY A;  5D1U A;  4JPA A;  1ROS A;  3KRY A;  5BOT A;  4WKI A;  3O64 A;  1G9K A;  3VTG A;  1XFU A;  3DWB A;  3V96 B;  3KEJ A;  3CKI A;  1HY7 A;  1R1H A;  1PWW A;  2XS4 A;  4PKU A;  1G49 A;  1A86 A;  3KME A;  3HDB A;  1AST A;  1EB6 A;  4PKW A;  5L79 A;  3VI1 A;  1CGE A;  5I0L A;  2YIG A;  4AUO A;  1SLM A;  1RMZ A;  2TCL A;  4GR8 A;  1S4B P;  2OW2 A;  3EDI A;  2J0T A;  3KWV C;  5I2Z A;  4G0D A;  2OXW A;  3B8Z A;  1H71 P;  1YCM A;  1IAE A;  4AYK A;  1JAP A;  3ELM A;  1ATL A;  4I35 A;  4A7B A;  1KUK A;  3WV3 A;  2MZE A;  5H8X A;  1BM6 A;  2RJQ A;  1XFZ A;  3B2Z A;  4JQG A;  1PWQ A;  3AYK A;  1HTD A;  5CXA A;  1AF0 A;  1KUG A;  2X7M A;  1GE7 A;  3MA2 A;  4H84 A;  1Y0V A;  2FV9 A;  1D8F A;  1D5J A;  1XFX A;  2K9C A;  4GWN A;  3TS4 A;  3DTK A;  3LJG A;  3LMC A;  2CLT A;  3DPE A;  1K7I A;  966C A;  3E8R A;  1FLS A;  2OW0 A;  2ERO A;  1DTH A;  1YP1 A;  1BZS A;  2YUF A;  3F16 A;  3I7G A;  3RTS A;  3AYU A;  3EHX A;  2N8R A;  1XM5 A;  3HY9 A;  1BUV M;  3EDH A;  1I76 A;  1SMP A;  4A3W A;  3U1R A;  3KHI A;  1QIB A;  3LJZ A;  2A8H A;  1OMJ A;  4XM7 A;  3DSL A;  2Y6C A;  4IJO A;  3HBU P;  3GBO A;  3BA0 A;  1Q3A A;  4HX3 A;  3F18 A;  1JIW P;  1XAX A;  1CQR A;  1UTT A;  4ON1 A;  5I4O A;  1KBC A;  3LUN A;  1D7X A;  4FXQ A;  1MMQ A;  2MZI A;  3G5C A;  1OS2 A;  2ERP A;  2OY4 A;  4L63 A;  2OY2 A;  1MMP A;  2I47 A;  1Z3J A;  5JMY A;  2X3B A;  3SHI A;  4AXQ A;  3LK8 A;  3OHL A;  1WNI A;  4AIG A;  5I43 A;  3ZVS A;  2OVX A;  1IAD A;  4GF1 A;  2JIH A;  3TT4 A;  4L19 A;  2OZR A;  4JP4 A;  3I7I A;  1ZTQ A;  1C7K A;  4IN9 A;  2JT5 A;  1J7N A;  1A85 A;  5D1T A;  1MMR A;  4PKV A;  2DW1 A;  4WZV A;  3LJT A;  1ZS0 A;  3EWJ A;  1B8Y A;  3P1V A;  2POJ A;  1JIZ A;  1C8T A;  3DTE A;  1KUI A;  1SLN A;  5D3C A;  4L6T A;  2AIG P;  1CGF A;  2DDY A;  1QJJ A;  4HMA A;  2W13 A;  3UVC A;  1SU3 A;  3LIR A;  4GR3 A;  1RM8 A;  2K2G A;  1UTZ A;  1KUH A;  1TVI A;  1QIC A;  4JA1 A;  4H49 A;  3NX7 A;  1O0T A;  1JK3 A;  3EDZ A;  3LKA A;  1G4K A;  2PJT A;  2XS3 A;  1EAK A;  2ERQ A;  3B92 A;  4GUY A;  1K7Q A;  1JAQ A;  1XUR A;  3Q2G A;  2WOA A;  5D1S A;  3RTT A;  3HBV P;  3N2V A;  1HFS A;  1SAT A;  1XFW A;  1DMT A;  2Z2D A;  1IAC A;  1JAO A;  1XFY A;  1R1J A;  3EDG A;  4XBH A;  3F15 A;  1QJI A;  2W0D A;  4DV8 A;  4WK7 A;  2JNP A;  4GR0 A;  1GE6 A;  3F1A A;  3DPF A;  4GQL A;  2JSD A;  1BSW A;  1BKC A;  4H76 A;  3K7N A;  4JIJ A;  3TSK A;  2KRJ A;  1K7G A;  2OXZ A;  1OM7 A;  3TVC A;  3F17 A;  1BUD A;  1AYK A;  5B5P A;  2W14 A;  4XCT A;  5B5O A;  1I1I P;  3USN A;  1BQQ M;  2OI0 A;  4I03 A;  5CZM A;  3G42 A;  2E2D A;  1R54 A;  1D8M A;  1Y93 A;  5CUH A;  1SRP A;  5BOY A;  3HDA P;  5L7F A;  4XM8 A;  1CAQ A;  4H82 A;  3LIL A;  1C3I A;  2USN A;  2D1O A;  1OS9 A;  2D1N A;  3HYG A;  2OW1 A;  4PKQ A;  456C A;  1L6J A;  3OHO A;  1OM8 A;  3P24 A;  1JAN A;  3KEK A;  3O2X A;  5D2B A;  1USN A;  3Q2H A;  1BQO A;  1IAB A;  1GXD A;  4PKT A;  2CKI A;  2Y6D A;  2OVZ A;  1BKC I;  3HY7 A;  1UMS A;  4L7A A;  1QUA A;  1ND1 A;  3AIG A;  3EHY A;  4H1Q A;  1R55 A;  4WKE A;  1PWU A;  1R1I A;  1JJ9 A;  1HOV A;  5I12 A;  1BKC E;  1Y8J A;  1B3D A;  4GWM A;  3KMC A;  2OW9 A;  2SRT A;  2MZH A;  3K7L A;  1GO7 P;  3LIK A;  2HU6 A;  1CK7 A;  5I3M A;  1OZ9 A;  2RJP A;  5BPA A;  3KEC A;  3ZUK A;  4WF6 A;  3DTI A;  1OO9 A;  4FU4 A;  2W12 A;  4H2E A;  1CXV A;  2W15 A;  1MMB A;  3L0T A;  4R3V A;  2J83 A;  2WO8 A;  2WO9 A;  1G12 A;  4EFS A;  3N2U A;  1UMT A;  1GKD A;  3F19 A; 
#chains in the Genus database with same CATH homology
 3LGP A;  3LUM A;  2DW0 A;  1JKY A;  2L0R A;  3LQ0 A;  4XM6 A;  1PWP A;  1CIZ A;  4DD8 A;  1QIA A;  2O36 A;  4CTH A;  1ZXV A;  4Q1L A;  3DL1 A;  3ZXH A;  1OM6 A;  2X3A A;  1FM1 A;  1XUC A;  4H30 A;  2X3C A;  1ZP5 A;  3LE9 A;  2DDF A;  3HB2 P;  1KAP P;  1AKL A;  1IAA A;  3L0V A;  1BIW A;  2JT6 A;  1UEA A;  1IAG A;  1G05 A;  2OXU A;  1GE5 A;  4PKR A;  4J4M A;  4G9L A;  5LAB A;  1EUB A;  4FXY P;  830C A;  1HV5 A;  1CGL A;  4PKS A;  2YB9 A;  3LQB A;  2AYK A;  4ILW D;  4DF9 A;  1O0Q A;  4FVL A;  1PWV A;  1XUD A;  1YOU A;  4IUW A;  4QKZ A;  4ZR5 A;  1ZXC A;  3LEA A;  1GKC A;  3DNG A;  2MLS A;  1XFV A;  1GO8 P;  2MLR A;  2QPJ A;  4DPE A;  2E3X A;  3WV2 A;  2O3E A;  3WV1 A;  1FBL A;  2DW2 A;  1KUF A;  2FV5 A;  2V4B A;  4H3X A;  1JH1 A;  1I73 A;  1ZVX A;  5D7W A;  1MNC A;  1HFC A;  1YQY A;  5D1U A;  4JPA A;  1ROS A;  3KRY A;  5BOT A;  4WKI A;  3O64 A;  1G9K A;  3VTG A;  1XFU A;  3DWB A;  3V96 B;  3KEJ A;  3CKI A;  1HY7 A;  1R1H A;  1PWW A;  2XS4 A;  4PKU A;  1G49 A;  1A86 A;  3KME A;  3HDB A;  1AST A;  1EB6 A;  4PKW A;  5L79 A;  3VI1 A;  1CGE A;  5I0L A;  2YIG A;  4AUO A;  1SLM A;  1RMZ A;  2TCL A;  4GR8 A;  1S4B P;  2OW2 A;  3EDI A;  2J0T A;  3KWV C;  5I2Z A;  4G0D A;  2OXW A;  3B8Z A;  1H71 P;  1YCM A;  1IAE A;  4AYK A;  1JAP A;  3ELM A;  1ATL A;  4I35 A;  4A7B A;  1KUK A;  3WV3 A;  2MZE A;  5H8X A;  1BM6 A;  2RJQ A;  1XFZ A;  3B2Z A;  4JQG A;  1PWQ A;  3AYK A;  1HTD A;  5CXA A;  1AF0 A;  1KUG A;  2X7M A;  1GE7 A;  3MA2 A;  4H84 A;  1Y0V A;  2FV9 A;  1D8F A;  1D5J A;  1XFX A;  2K9C A;  4GWN A;  3TS4 A;  3DTK A;  3LJG A;  3LMC A;  2CLT A;  3DPE A;  1K7I A;  966C A;  3E8R A;  1FLS A;  2OW0 A;  2ERO A;  1DTH A;  1YP1 A;  1BZS A;  2YUF A;  3F16 A;  3I7G A;  3RTS A;  3AYU A;  3EHX A;  2N8R A;  3HY9 A;  1BUV M;  3EDH A;  1I76 A;  1SMP A;  4A3W A;  3U1R A;  3KHI A;  1QIB A;  3LJZ A;  2A8H A;  1OMJ A;  4XM7 A;  3DSL A;  2Y6C A;  4IJO A;  3HBU P;  3GBO A;  3BA0 A;  1Q3A A;  4HX3 A;  3F18 A;  1JIW P;  1CQR A;  1UTT A;  4ON1 A;  5I4O A;  1KBC A;  3LUN A;  1D7X A;  4FXQ A;  1MMQ A;  2MZI A;  3G5C A;  1OS2 A;  2ERP A;  2OY4 A;  4L63 A;  2OY2 A;  1MMP A;  2I47 A;  1Z3J A;  5JMY A;  2X3B A;  3SHI A;  4AXQ A;  3LK8 A;  3OHL A;  1WNI A;  4AIG A;  5I43 A;  3ZVS A;  2OVX A;  1IAD A;  4GF1 A;  2JIH A;  3TT4 A;  4L19 A;  2OZR A;  4JP4 A;  3I7I A;  1ZTQ A;  1C7K A;  4IN9 A;  2JT5 A;  1J7N A;  1A85 A;  5D1T A;  1MMR A;  4PKV A;  2DW1 A;  4WZV A;  3LJT A;  1ZS0 A;  3EWJ A;  1B8Y A;  3P1V A;  2POJ A;  1JIZ A;  1C8T A;  3DTE A;  1KUI A;  1SLN A;  5D3C A;  4L6T A;  2AIG P;  1CGF A;  2DDY A;  1QJJ A;  4HMA A;  2W13 A;  3UVC A;  1SU3 A;  3LIR A;  4GR3 A;  1RM8 A;  2K2G A;  1UTZ A;  1KUH A;  1QIC A;  4JA1 A;  4H49 A;  3NX7 A;  1O0T A;  1JK3 A;  3EDZ A;  3LKA A;  1G4K A;  2PJT A;  2XS3 A;  1EAK A;  2ERQ A;  3B92 A;  4GUY A;  1K7Q A;  1JAQ A;  1XUR A;  3Q2G A;  2WOA A;  5D1S A;  3RTT A;  3HBV P;  3N2V A;  1HFS A;  1SAT A;  1XFW A;  1DMT A;  2Z2D A;  1IAC A;  1JAO A;  1XFY A;  1R1J A;  3EDG A;  4XBH A;  3F15 A;  1QJI A;  2W0D A;  4DV8 A;  4WK7 A;  2JNP A;  4GR0 A;  1GE6 A;  3F1A A;  3DPF A;  4GQL A;  2JSD A;  1BSW A;  1BKC A;  4H76 A;  3K7N A;  4JIJ A;  3TSK A;  2KRJ A;  1K7G A;  2OXZ A;  1OM7 A;  3TVC A;  3F17 A;  1BUD A;  1AYK A;  5B5P A;  2W14 A;  4XCT A;  5B5O A;  1I1I P;  3USN A;  1BQQ M;  2OI0 A;  4I03 A;  5CZM A;  3G42 A;  2E2D A;  1R54 A;  1D8M A;  1Y93 A;  5CUH A;  1SRP A;  5BOY A;  3HDA P;  5L7F A;  4XM8 A;  1CAQ A;  4H82 A;  3LIL A;  1C3I A;  2USN A;  2D1O A;  1OS9 A;  2D1N A;  3HYG A;  2OW1 A;  4PKQ A;  456C A;  1L6J A;  3OHO A;  1OM8 A;  3P24 A;  1JAN A;  3KEK A;  3O2X A;  5D2B A;  1USN A;  3Q2H A;  1BQO A;  1IAB A;  1GXD A;  4PKT A;  2CKI A;  2Y6D A;  2OVZ A;  1BKC I;  3HY7 A;  1UMS A;  4L7A A;  1QUA A;  1ND1 A;  3AIG A;  3EHY A;  4H1Q A;  1R55 A;  4WKE A;  1PWU A;  1R1I A;  1JJ9 A;  1HOV A;  5I12 A;  1BKC E;  1Y8J A;  1B3D A;  4GWM A;  3KMC A;  2OW9 A;  2SRT A;  2MZH A;  3K7L A;  1GO7 P;  3LIK A;  2HU6 A;  1CK7 A;  5I3M A;  2RJP A;  5BPA A;  3KEC A;  3ZUK A;  4WF6 A;  3DTI A;  1OO9 A;  4FU4 A;  2W12 A;  4H2E A;  1CXV A;  2W15 A;  1MMB A;  3L0T A;  4R3V A;  2J83 A;  2WO8 A;  2WO9 A;  1G12 A;  4EFS A;  3N2U A;  1UMT A;  1GKD A;  3F19 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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