1IAEA

Crystal structures, spectroscopic features, and catalytic properties of cobalt(ii), copper(ii), nickel(ii), and mercury(ii) derivatives of the zinc endopeptidase astacin. a correlation of structure and proteolytic activity
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
200
structure length
200
Chain Sequence
AAILGDEYLWSGGVIPYTFAGVSGADQSAILSGMQELEEKTCIRFVPRTTESDYVEIFTSGSGCWSYVGRISGAQQVSLQANGCVYHGTIIHELMHAIGFYHEHTRMDRDNYVTINYQNVDPSMTSNFDIDTYSRYVGEDYQYYSIMHYGKYSFSIQWGVLETIVPLQNGIDLTDPYDKAHMLQTDANQINNLYTNECSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Zinc endopeptidase
source organism Astacus astacus
publication title Crystal structures, spectroscopic features, and catalytic properties of cobalt(II), copper(II), nickel(II), and mercury(II) derivatives of the zinc endopeptidase astacin. A correlation of structure and proteolytic activity.
pubmed rcsb
molecule keywords ASTACIN
total genus 67
structure length 200
sequence length 200
ec nomenclature ec 3.4.24.21: Astacin.
pdb deposition date 1994-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01400 Astacin Astacin (Peptidase family M12A)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1iaeA00
2OY2A 2K2GA 2JIHA 1OS9A 5D3CA 1A86A 2KRJA 5CZMA 1AYKA 1CQRA 5D7WA 2OVZA 1ASTA 5CXAA 1XUCA 1XURA 2L0RA 4ZR5A 3BA0A 1QICA 3VI1A 1CXVA 1IAAA 1SLMA 1ZVXA 4AYKA 3V96B 2X3BA 3LKAA 5B5PA 1XFUA 1GKCA 1HOVA 1IADA 2MZHA 4A7BA 1OMJA 5D1SA 1ATLA 3K7LA 3L0VA 3I7IA 3TSKA 1R1HA 1ZXVA 2OY4A 1A85A 4H30A 2DW2A 1FLSA 3LEAA 4WK7A 3EDGA 3NX7A 4WKIA 1JIWP 1JAQA 3Q2GA 3ZUKA 4HX3A 5CUHA 3WV2A 4JPAA 3TT4A 4DD8A 1AF0A 3P1VA 1BUVM 3B8ZA 4PKUA 1GKDA 4GQLA 5LABA 3I7GA 1IAEA 3OHLA 5B5OA 5L7FA 2AIGP 3LQBA 1G12A 1HV5A 3KEJA 4AIGA 1XFVA 1GE6A 1Y93A 2MLRA 1OM7A 3HY7A 5L79A 3B92A 2OI0A 3KHIA 2HU6A 4FU4A 3LK8A 4JIJA 1L6JA 1SATA 4PKVA 3ZVSA 3Q2HA 4HMAA 1DTHA 1PWVA 1KUHA 1UMSA 4QKZA 1QJJA 1RMZA 1GE5A 2I47A 2JT5A 3TVCA 2DW1A 2Y6DA 1O0TA 5I43A 1KUGA 2PJTA 1G9KA 3AIGA 3LUMA 4I35A 1EAKA 4H2EA 1MMPA 1R55A 1QIAA 5BPAA 1CGLA 4GWNA 4IUWA 1WNIA 1OO9A 4R3VA 1MMRA 3TS4A 3DPEA 1D8FA 3DL1A 5I4OA 830CA 3LIKA 966CA 2W0DA 4H82A 5I0LA 2Y6CA 1BZSA 3EDHA 1O0QA 2AYKA 4PKWA 2OXZA 2X3AA 1BQOA 4XM6A 4WKEA 1SMPA 4FXQA 4WF6A 1H71P 3EHYA 1JIZA 4PKRA 3O64A 4GUYA 3DNGA 1HFCA 1PWQA 2X7MA 4JA1A 3KWVC 3F15A 3MA2A 1BKCI 1UTTA 3KEKA 1EB6A 3O2XA 3N2UA 1XFYA 1C7KA 3DPFA 1Y8JA 1D8MA 2QPJA 456CA 1Q3AA 5D2BA 1KBCA 4AUOA 1JKYA 5I2ZA 3USNA 3RTTA 3OHOA 3LQ0A 3E8RA 1G4KA 1AKLA 1YP1A 2K9CA 3EDZA 1XFWA 1BKCE 2D1NA 1GO8P 2W15A 1Y0VA 2OW9A 3LMCA 4ILWD 2WO9A 3P24A 5I3MA 4FVLA 2OVXA 1OM6A 4Q1LA 1OS2A 1HTDA 4WZVA 2DW0A 2FV9A 1I73A 1FM1A 1ROSA 1JANA 1B8YA 2E2DA 4H3XA 2TCLA 2J0TA 1YOUA 1CGEA 3L0TA 2OW2A 1KUIA 4DF9A 2A8HA 4L19A 3LILA 1R1JA 1Z3JA 3VTGA 4H49A 1G49A 4CTHA 1IABA 1KUKA 2FV5A 3LE9A 1QUAA 2YIGA 3LGPA 5I12A 2E3XA 1PWWA 1XUDA 3HDAP 1B3DA 3HBVP 4GWMA 1GO7P 5BOTA 4XM7A 4XBHA 1SRPA 2XS3A 4PKSA 4FXYP 3HBUP 1I76A 4G0DA 5JMYA 2N8RA 4IN9A 1KAPP 3LJGA 1BIWA 2JSDA 1BQQM 3U1RA 4A3WA 1JAPA 1CIZA 3HB2P 1C3IA 2DDFA 1JH1A 1ZS0A 2CLTA 2WOAA 5D1TA 3WV3A 3F1AA 5H8XA 2SRTA 1ZXCA 3CKIA 3RTSA 1PWUA 1J7NA 3GBOA 4XCTA 2OXUA 1K7IA 3EHXA 2W14A 3N2VA 3B2ZA 4GF1A 2RJQA 2DDYA 1CK7A 4JQGA 4IJOA 1DMTA 1JK3A 1MMBA 1PWPA 1D7XA 1KUFA 2V4BA 2WO8A 1QIBA 2W13A 4DPEA 1BM6A 3G5CA 1IACA 1JAOA 2JNPA 4JP4A 3F18A 1CAQA 3LJTA 2Z2DA 5D1UA 3ZXHA 2XS4A 1BSWA 1SU3A 4PKQA 1ND1A 1SLNA 1R1IA 4AXQA 3ELMA 4DV8A 1MMQA 4G9LA 3WV1A 1EUBA 3F16A 4H76A 2POJA 2CKIA 1IAGA 4PKTA 1ZTQA 1RM8A 3SHIA 3LIRA 1YQYA 2USNA 3UVCA 2X3CA 1FBLA 3HYGA 4ON1A 2MZEA 1R54A 1CGFA 3LUNA 1S4BP 3F19A 2EROA 1GXDA 4GR3A 1K7QA 1JJ9A 1XFZA 2ERPA 3LJZA 3AYUA 1BKCA 2MZIA 1XFXA 4EFSA 2MLSA 1OM8A 1GE7A 4L6TA 4GR0A 2ERQA 1G05A 2J83A 4H1QA 1ZP5A 3K7NA 3DSLA 4GR8A 1UMTA 3KMEA 1QJIA 3KECA 4I03A 1BUDA 3KRYA 1UEAA 2O36A 4XM8A 1K7GA 2YB9A 3G42A 3AYKA 2O3EA 1USNA 2OZRA 1UTZA 2JT6A 2OW0A 1HY7A 3HDBA 3KMCA 1MNCA 1YCMA 1C8TA 2RJPA 2OXWA 4J4MA 4H84A 5BOYA 3EDIA 3DWBA 3HY9A 3F17A 2W12A 2OW1A 1D5JA 4L63A 3EWJA 1I1IP 1HFSA 2D1OA
chains in the Genus database with same CATH superfamily
2OY2A 2K2GA 2JIHA 1OS9A 5D3CA 1A86A 2KRJA 5CZMA 1AYKA 1CQRA 5D7WA 2OVZA 1ASTA 5CXAA 1XUCA 1XURA 2L0RA 4ZR5A 3BA0A 1QICA 3VI1A 1CXVA 1IAAA 1SLMA 1ZVXA 4AYKA 3V96B 2X3BA 3LKAA 5B5PA 1XFUA 1GKCA 1HOVA 1IADA 2MZHA 4A7BA 1OMJA 5D1SA 1ATLA 3K7LA 3L0VA 3I7IA 3TSKA 1R1HA 1ZXVA 2OY4A 1A85A 4H30A 2DW2A 1FLSA 3LEAA 4WK7A 3EDGA 3NX7A 4WKIA 1JIWP 1JAQA 3Q2GA 3ZUKA 4HX3A 5CUHA 3WV2A 4JPAA 3TT4A 4DD8A 1AF0A 3P1VA 1BUVM 3B8ZA 3DTEA 4PKUA 1GKDA 4GQLA 5LABA 3I7GA 1IAEA 3OHLA 5B5OA 5L7FA 2AIGP 3LQBA 1G12A 1HV5A 3DTIA 3KEJA 4AIGA 1XFVA 1GE6A 1Y93A 2MLRA 1OM7A 3HY7A 5L79A 3B92A 2OI0A 3KHIA 2HU6A 4FU4A 3LK8A 4JIJA 1L6JA 1SATA 4PKVA 3ZVSA 3Q2HA 4HMAA 1DTHA 1PWVA 1KUHA 1UMSA 4QKZA 1QJJA 1RMZA 1GE5A 2I47A 2JT5A 1OZ9A 3TVCA 2DW1A 2Y6DA 1O0TA 5I43A 1KUGA 2PJTA 1G9KA 3AIGA 3LUMA 4I35A 1EAKA 4H2EA 1MMPA 1R55A 1QIAA 5BPAA 1CGLA 4GWNA 4IUWA 1WNIA 1TVIA 1OO9A 4R3VA 1MMRA 3TS4A 3DPEA 1D8FA 3DL1A 5I4OA 830CA 3LIKA 966CA 2W0DA 4H82A 5I0LA 2Y6CA 1BZSA 3EDHA 1O0QA 2AYKA 4PKWA 2OXZA 2X3AA 1BQOA 4XM6A 4WKEA 1SMPA 4FXQA 4WF6A 1H71P 3EHYA 1JIZA 4PKRA 3O64A 4GUYA 3DNGA 1XM5A 1HFCA 1PWQA 2X7MA 4JA1A 3KWVC 3F15A 3MA2A 1BKCI 1UTTA 3KEKA 1EB6A 3O2XA 3N2UA 1XFYA 1C7KA 3DPFA 1Y8JA 1D8MA 2QPJA 456CA 1Q3AA 5D2BA 1KBCA 4AUOA 1JKYA 5I2ZA 3USNA 3RTTA 3OHOA 3LQ0A 3E8RA 1G4KA 1AKLA 1YP1A 2K9CA 3EDZA 1XFWA 1BKCE 2D1NA 1GO8P 2W15A 1Y0VA 2OW9A 3LMCA 2YUFA 4ILWD 2WO9A 3P24A 5I3MA 4FVLA 2OVXA 1OM6A 4Q1LA 1OS2A 1HTDA 4WZVA 2DW0A 2FV9A 1I73A 1FM1A 1ROSA 1JANA 1B8YA 2E2DA 4H3XA 2TCLA 2J0TA 1YOUA 1CGEA 3L0TA 2OW2A 1KUIA 4DF9A 2A8HA 4L19A 3LILA 1R1JA 1Z3JA 3VTGA 4H49A 1G49A 4CTHA 1IABA 1KUKA 2FV5A 3LE9A 1QUAA 2YIGA 3LGPA 5I12A 2E3XA 1PWWA 1XUDA 3HDAP 1B3DA 3HBVP 4GWMA 1GO7P 5BOTA 4XM7A 4XBHA 1SRPA 2XS3A 4PKSA 4FXYP 3HBUP 1I76A 4G0DA 5JMYA 2N8RA 4IN9A 1KAPP 3LJGA 1BIWA 2JSDA 1BQQM 3U1RA 4A3WA 1JAPA 1CIZA 3HB2P 1C3IA 2DDFA 1JH1A 1ZS0A 2CLTA 2WOAA 5D1TA 3WV3A 3F1AA 5H8XA 2SRTA 1ZXCA 3CKIA 3RTSA 1PWUA 1J7NA 3GBOA 4XCTA 2OXUA 1K7IA 3EHXA 2W14A 3N2VA 3B2ZA 4GF1A 2RJQA 2DDYA 1CK7A 4JQGA 4IJOA 1DMTA 1JK3A 1MMBA 1PWPA 1D7XA 1KUFA 2V4BA 2WO8A 1QIBA 2W13A 4DPEA 1BM6A 3G5CA 1IACA 4L7AA 1JAOA 2JNPA 4JP4A 3F18A 1CAQA 3LJTA 2Z2DA 5D1UA 3ZXHA 2XS4A 1BSWA 1SU3A 4PKQA 1ND1A 1SLNA 1R1IA 4AXQA 3ELMA 4DV8A 1MMQA 4G9LA 3WV1A 1EUBA 3F16A 4H76A 2POJA 2CKIA 1IAGA 4PKTA 1ZTQA 1RM8A 3SHIA 3LIRA 1YQYA 2USNA 3UVCA 2X3CA 1FBLA 3HYGA 4ON1A 2MZEA 1R54A 1CGFA 3LUNA 1S4BP 3F19A 2EROA 1GXDA 4GR3A 1K7QA 1JJ9A 1XFZA 2ERPA 3LJZA 3AYUA 1BKCA 2MZIA 1XFXA 4EFSA 2MLSA 1OM8A 1GE7A 4L6TA 4GR0A 2ERQA 1G05A 2J83A 4H1QA 1XAXA 1ZP5A 3K7NA 3DSLA 4GR8A 1UMTA 3KMEA 1QJIA 3KECA 4I03A 1BUDA 3KRYA 1UEAA 3DTKA 2O36A 4XM8A 1K7GA 2YB9A 3G42A 3AYKA 2O3EA 1USNA 2OZRA 1UTZA 2JT6A 2OW0A 1HY7A 3HDBA 3KMCA 1MNCA 1YCMA 1C8TA 2RJPA 2OXWA 4J4MA 4H84A 5BOYA 3EDIA 3DWBA 3HY9A 3F17A 2W12A 2OW1A 1D5JA 4L63A 3EWJA 1I1IP 1HFSA 2D1OA
chains in the Genus database with same CATH topology
2OY2A 2K2GA 2JIHA 1OS9A 5D3CA 1A86A 2KRJA 5CZMA 1AYKA 1CQRA 5D7WA 2OVZA 1ASTA 5CXAA 1XUCA 1XURA 2L0RA 4ZR5A 3BA0A 1QICA 3VI1A 1CXVA 1IAAA 1SLMA 1ZVXA 4AYKA 3V96B 2X3BA 3LKAA 5B5PA 1XFUA 1GKCA 1HOVA 1IADA 2MZHA 4A7BA 1OMJA 5D1SA 1ATLA 3K7LA 3L0VA 3I7IA 3TSKA 1R1HA 1ZXVA 2OY4A 1A85A 4H30A 2DW2A 1FLSA 3LEAA 4WK7A 3EDGA 3NX7A 4WKIA 1JIWP 1JAQA 3Q2GA 3ZUKA 4HX3A 5CUHA 3WV2A 4JPAA 3TT4A 4DD8A 1AF0A 3P1VA 1BUVM 3B8ZA 3DTEA 4PKUA 1GKDA 4GQLA 5LABA 3I7GA 1IAEA 3OHLA 5B5OA 5L7FA 2AIGP 3LQBA 1G12A 1HV5A 3DTIA 3KEJA 4AIGA 1XFVA 1GE6A 1Y93A 2MLRA 1OM7A 3HY7A 5L79A 3B92A 2OI0A 3KHIA 2HU6A 4FU4A 3LK8A 4JIJA 1L6JA 1SATA 4PKVA 3ZVSA 3Q2HA 4HMAA 1DTHA 1PWVA 1KUHA 1UMSA 4QKZA 1QJJA 1RMZA 1GE5A 2I47A 2JT5A 3TVCA 2DW1A 2Y6DA 1O0TA 5I43A 1KUGA 2PJTA 1G9KA 3AIGA 3LUMA 4I35A 1EAKA 4H2EA 1MMPA 1R55A 1QIAA 5BPAA 1CGLA 4GWNA 4IUWA 1WNIA 1OO9A 4R3VA 1MMRA 3TS4A 3DPEA 1D8FA 3DL1A 5I4OA 830CA 3LIKA 966CA 2W0DA 4H82A 5I0LA 2Y6CA 1BZSA 3EDHA 1O0QA 2AYKA 4PKWA 2OXZA 2X3AA 1BQOA 4XM6A 4WKEA 1SMPA 4FXQA 4WF6A 1H71P 3EHYA 1JIZA 4PKRA 3O64A 4GUYA 3DNGA 1HFCA 1PWQA 2X7MA 4JA1A 3KWVC 3F15A 3MA2A 1BKCI 1UTTA 3KEKA 1EB6A 3O2XA 3N2UA 1XFYA 1C7KA 3DPFA 1Y8JA 1D8MA 2QPJA 456CA 1Q3AA 5D2BA 1KBCA 4AUOA 1JKYA 5I2ZA 3USNA 3RTTA 3OHOA 3LQ0A 3E8RA 1G4KA 1AKLA 1YP1A 2K9CA 3EDZA 1XFWA 1BKCE 2D1NA 1GO8P 2W15A 1Y0VA 2OW9A 3LMCA 2YUFA 4ILWD 2WO9A 3P24A 5I3MA 4FVLA 2OVXA 1OM6A 4Q1LA 1OS2A 1HTDA 4WZVA 2DW0A 2FV9A 1I73A 1FM1A 1ROSA 1JANA 1B8YA 2E2DA 4H3XA 2TCLA 2J0TA 1YOUA 1CGEA 3L0TA 2OW2A 1KUIA 4DF9A 2A8HA 4L19A 3LILA 1R1JA 1Z3JA 3VTGA 4H49A 1G49A 4CTHA 1IABA 1KUKA 2FV5A 3LE9A 1QUAA 2YIGA 3LGPA 5I12A 2E3XA 1PWWA 1XUDA 3HDAP 1B3DA 3HBVP 4GWMA 1GO7P 5BOTA 4XM7A 4XBHA 1SRPA 2XS3A 4PKSA 4FXYP 3HBUP 1I76A 4G0DA 5JMYA 2N8RA 4IN9A 1KAPP 3LJGA 1BIWA 2JSDA 1BQQM 3U1RA 4A3WA 1JAPA 1CIZA 3HB2P 1C3IA 2DDFA 1JH1A 1ZS0A 2CLTA 2WOAA 5D1TA 3WV3A 3F1AA 5H8XA 2SRTA 1ZXCA 3CKIA 3RTSA 1PWUA 1J7NA 3GBOA 4XCTA 2OXUA 1K7IA 3EHXA 2W14A 3N2VA 3B2ZA 4GF1A 2RJQA 2DDYA 1CK7A 4JQGA 4IJOA 1DMTA 1JK3A 1MMBA 1PWPA 1D7XA 1KUFA 2V4BA 2WO8A 1QIBA 2W13A 4DPEA 1BM6A 3G5CA 1IACA 4L7AA 1JAOA 2JNPA 4JP4A 3F18A 1CAQA 3LJTA 2Z2DA 5D1UA 3ZXHA 2XS4A 1BSWA 1SU3A 4PKQA 1ND1A 1SLNA 1R1IA 4AXQA 3ELMA 4DV8A 1MMQA 4G9LA 3WV1A 1EUBA 3F16A 4H76A 2POJA 2CKIA 1IAGA 4PKTA 1ZTQA 1RM8A 3SHIA 3LIRA 1YQYA 2USNA 3UVCA 2X3CA 1FBLA 3HYGA 4ON1A 2MZEA 1R54A 1CGFA 3LUNA 1S4BP 3F19A 2EROA 1GXDA 4GR3A 1K7QA 1JJ9A 1XFZA 2ERPA 3LJZA 3AYUA 1BKCA 2MZIA 1XFXA 4EFSA 2MLSA 1OM8A 1GE7A 4L6TA 4GR0A 2ERQA 1G05A 2J83A 4H1QA 1ZP5A 3K7NA 3DSLA 4GR8A 1UMTA 3KMEA 1QJIA 3KECA 4I03A 1BUDA 3KRYA 1UEAA 3DTKA 2O36A 4XM8A 1K7GA 2YB9A 3G42A 3AYKA 2O3EA 1USNA 2OZRA 1UTZA 2JT6A 2OW0A 1HY7A 3HDBA 3KMCA 1MNCA 1YCMA 1C8TA 2RJPA 2OXWA 4J4MA 4H84A 5BOYA 3EDIA 3DWBA 3HY9A 3F17A 2W12A 2OW1A 1D5JA 4L63A 3EWJA 1I1IP 1HFSA 2D1OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OY2 A;  2K2G A;  2JIH A;  1OS9 A;  5D3C A;  1A86 A;  2KRJ A;  5CZM A;  1AYK A;  1CQR A;  5D7W A;  2OVZ A;  1AST A;  5CXA A;  1XUC A;  1XUR A;  2L0R A;  4ZR5 A;  3BA0 A;  1QIC A;  3VI1 A;  1CXV A;  1IAA A;  1SLM A;  1ZVX A;  4AYK A;  3V96 B;  2X3B A;  3LKA A;  5B5P A;  1XFU A;  1GKC A;  1HOV A;  1IAD A;  2MZH A;  4A7B A;  1OMJ A;  5D1S A;  1ATL A;  3K7L A;  3L0V A;  3I7I A;  3TSK A;  1R1H A;  1ZXV A;  2OY4 A;  1A85 A;  4H30 A;  2DW2 A;  1FLS A;  3LEA A;  4WK7 A;  3EDG A;  3NX7 A;  4WKI A;  1JIW P;  1JAQ A;  3Q2G A;  3ZUK A;  4HX3 A;  5CUH A;  3WV2 A;  4JPA A;  3TT4 A;  4DD8 A;  1AF0 A;  3P1V A;  1BUV M;  3B8Z A;  4PKU A;  1GKD A;  4GQL A;  5LAB A;  3I7G A;  1IAE A;  3OHL A;  5B5O A;  5L7F A;  2AIG P;  3LQB A;  1G12 A;  1HV5 A;  3KEJ A;  4AIG A;  1XFV A;  1GE6 A;  1Y93 A;  2MLR A;  1OM7 A;  3HY7 A;  5L79 A;  3B92 A;  2OI0 A;  3KHI A;  2HU6 A;  4FU4 A;  3LK8 A;  4JIJ A;  1L6J A;  1SAT A;  4PKV A;  3ZVS A;  3Q2H A;  4HMA A;  1DTH A;  1PWV A;  1KUH A;  1UMS A;  4QKZ A;  1QJJ A;  1RMZ A;  1GE5 A;  2I47 A;  2JT5 A;  3TVC A;  2DW1 A;  2Y6D A;  1O0T A;  5I43 A;  1KUG A;  2PJT A;  1G9K A;  3AIG A;  3LUM A;  4I35 A;  1EAK A;  4H2E A;  1MMP A;  1R55 A;  1QIA A;  5BPA A;  1CGL A;  4GWN A;  4IUW A;  1WNI A;  1OO9 A;  4R3V A;  1MMR A;  3TS4 A;  3DPE A;  1D8F A;  3DL1 A;  5I4O A;  830C A;  3LIK A;  966C A;  2W0D A;  4H82 A;  5I0L A;  2Y6C A;  1BZS A;  3EDH A;  1O0Q A;  2AYK A;  4PKW A;  2OXZ A;  2X3A A;  1BQO A;  4XM6 A;  4WKE A;  1SMP A;  4FXQ A;  4WF6 A;  1H71 P;  3EHY A;  1JIZ A;  4PKR A;  3O64 A;  4GUY A;  3DNG A;  1HFC A;  1PWQ A;  2X7M A;  4JA1 A;  3KWV C;  3F15 A;  3MA2 A;  1BKC I;  1UTT A;  3KEK A;  1EB6 A;  3O2X A;  3N2U A;  1XFY A;  1C7K A;  3DPF A;  1Y8J A;  1D8M A;  2QPJ A;  456C A;  1Q3A A;  5D2B A;  1KBC A;  4AUO A;  1JKY A;  5I2Z A;  3USN A;  3RTT A;  3OHO A;  3LQ0 A;  3E8R A;  1G4K A;  1AKL A;  1YP1 A;  2K9C A;  3EDZ A;  1XFW A;  1BKC E;  2D1N A;  1GO8 P;  2W15 A;  1Y0V A;  2OW9 A;  3LMC A;  4ILW D;  2WO9 A;  3P24 A;  5I3M A;  4FVL A;  2OVX A;  1OM6 A;  4Q1L A;  1OS2 A;  1HTD A;  4WZV A;  2DW0 A;  2FV9 A;  1I73 A;  1FM1 A;  1ROS A;  1JAN A;  1B8Y A;  2E2D A;  4H3X A;  2TCL A;  2J0T A;  1YOU A;  1CGE A;  3L0T A;  2OW2 A;  1KUI A;  4DF9 A;  2A8H A;  4L19 A;  3LIL A;  1R1J A;  1Z3J A;  3VTG A;  4H49 A;  1G49 A;  4CTH A;  1IAB A;  1KUK A;  2FV5 A;  3LE9 A;  1QUA A;  2YIG A;  3LGP A;  5I12 A;  2E3X A;  1PWW A;  1XUD A;  3HDA P;  1B3D A;  3HBV P;  4GWM A;  1GO7 P;  5BOT A;  4XM7 A;  4XBH A;  1SRP A;  2XS3 A;  4PKS A;  4FXY P;  3HBU P;  1I76 A;  4G0D A;  5JMY A;  2N8R A;  4IN9 A;  1KAP P;  3LJG A;  1BIW A;  2JSD A;  1BQQ M;  3U1R A;  4A3W A;  1JAP A;  1CIZ A;  3HB2 P;  1C3I A;  2DDF A;  1JH1 A;  1ZS0 A;  2CLT A;  2WOA A;  5D1T A;  3WV3 A;  3F1A A;  5H8X A;  2SRT A;  1ZXC A;  3CKI A;  3RTS A;  1PWU A;  1J7N A;  3GBO A;  4XCT A;  2OXU A;  1K7I A;  3EHX A;  2W14 A;  3N2V A;  3B2Z A;  4GF1 A;  2RJQ A;  2DDY A;  1CK7 A;  4JQG A;  4IJO A;  1DMT A;  1JK3 A;  1MMB A;  1PWP A;  1D7X A;  1KUF A;  2V4B A;  2WO8 A;  1QIB A;  2W13 A;  4DPE A;  1BM6 A;  3G5C A;  1IAC A;  1JAO A;  2JNP A;  4JP4 A;  3F18 A;  1CAQ A;  3LJT A;  2Z2D A;  5D1U A;  3ZXH A;  2XS4 A;  1BSW A;  1SU3 A;  4PKQ A;  1ND1 A;  1SLN A;  1R1I A;  4AXQ A;  3ELM A;  4DV8 A;  1MMQ A;  4G9L A;  3WV1 A;  1EUB A;  3F16 A;  4H76 A;  2POJ A;  2CKI A;  1IAG A;  4PKT A;  1ZTQ A;  1RM8 A;  3SHI A;  3LIR A;  1YQY A;  2USN A;  3UVC A;  2X3C A;  1FBL A;  3HYG A;  4ON1 A;  2MZE A;  1R54 A;  1CGF A;  3LUN A;  1S4B P;  3F19 A;  2ERO A;  1GXD A;  4GR3 A;  1K7Q A;  1JJ9 A;  1XFZ A;  2ERP A;  3LJZ A;  3AYU A;  1BKC A;  2MZI A;  1XFX A;  4EFS A;  2MLS A;  1OM8 A;  1GE7 A;  4L6T A;  4GR0 A;  2ERQ A;  1G05 A;  2J83 A;  4H1Q A;  1ZP5 A;  3K7N A;  3DSL A;  4GR8 A;  1UMT A;  3KME A;  1QJI A;  3KEC A;  4I03 A;  1BUD A;  3KRY A;  1UEA A;  2O36 A;  4XM8 A;  1K7G A;  2YB9 A;  3G42 A;  3AYK A;  2O3E A;  1USN A;  2OZR A;  1UTZ A;  2JT6 A;  2OW0 A;  1HY7 A;  3HDB A;  3KMC A;  1MNC A;  1YCM A;  1C8T A;  2RJP A;  2OXW A;  4J4M A;  4H84 A;  5BOY A;  3EDI A;  3DWB A;  3HY9 A;  3F17 A;  2W12 A;  2OW1 A;  1D5J A;  4L63 A;  3EWJ A;  1I1I P;  1HFS A;  2D1O A; 
#chains in the Genus database with same CATH topology
 2OY2 A;  2K2G A;  2JIH A;  1OS9 A;  5D3C A;  1A86 A;  2KRJ A;  5CZM A;  1AYK A;  1CQR A;  5D7W A;  2OVZ A;  1AST A;  5CXA A;  1XUC A;  1XUR A;  2L0R A;  4ZR5 A;  3BA0 A;  1QIC A;  3VI1 A;  1CXV A;  1IAA A;  1SLM A;  1ZVX A;  4AYK A;  3V96 B;  2X3B A;  3LKA A;  5B5P A;  1XFU A;  1GKC A;  1HOV A;  1IAD A;  2MZH A;  4A7B A;  1OMJ A;  5D1S A;  1ATL A;  3K7L A;  3L0V A;  3I7I A;  3TSK A;  1R1H A;  1ZXV A;  2OY4 A;  1A85 A;  4H30 A;  2DW2 A;  1FLS A;  3LEA A;  4WK7 A;  3EDG A;  3NX7 A;  4WKI A;  1JIW P;  1JAQ A;  3Q2G A;  3ZUK A;  4HX3 A;  5CUH A;  3WV2 A;  4JPA A;  3TT4 A;  4DD8 A;  1AF0 A;  3P1V A;  1BUV M;  3B8Z A;  3DTE A;  4PKU A;  1GKD A;  4GQL A;  5LAB A;  3I7G A;  1IAE A;  3OHL A;  5B5O A;  5L7F A;  2AIG P;  3LQB A;  1G12 A;  1HV5 A;  3DTI A;  3KEJ A;  4AIG A;  1XFV A;  1GE6 A;  1Y93 A;  2MLR A;  1OM7 A;  3HY7 A;  5L79 A;  3B92 A;  2OI0 A;  3KHI A;  2HU6 A;  4FU4 A;  3LK8 A;  4JIJ A;  1L6J A;  1SAT A;  4PKV A;  3ZVS A;  3Q2H A;  4HMA A;  1DTH A;  1PWV A;  1KUH A;  1UMS A;  4QKZ A;  1QJJ A;  1RMZ A;  1GE5 A;  2I47 A;  2JT5 A;  1OZ9 A;  3TVC A;  2DW1 A;  2Y6D A;  1O0T A;  5I43 A;  1KUG A;  2PJT A;  1G9K A;  3AIG A;  3LUM A;  4I35 A;  1EAK A;  4H2E A;  1MMP A;  1R55 A;  1QIA A;  5BPA A;  1CGL A;  4GWN A;  4IUW A;  1WNI A;  1TVI A;  1OO9 A;  4R3V A;  1MMR A;  3TS4 A;  3DPE A;  1D8F A;  3DL1 A;  5I4O A;  830C A;  3LIK A;  966C A;  2W0D A;  4H82 A;  5I0L A;  2Y6C A;  1BZS A;  3EDH A;  1O0Q A;  2AYK A;  4PKW A;  2OXZ A;  2X3A A;  1BQO A;  4XM6 A;  4WKE A;  1SMP A;  4FXQ A;  4WF6 A;  1H71 P;  3EHY A;  1JIZ A;  4PKR A;  3O64 A;  4GUY A;  3DNG A;  1XM5 A;  1HFC A;  1PWQ A;  2X7M A;  4JA1 A;  3KWV C;  3F15 A;  3MA2 A;  1BKC I;  1UTT A;  3KEK A;  1EB6 A;  3O2X A;  3N2U A;  1XFY A;  1C7K A;  3DPF A;  1Y8J A;  1D8M A;  2QPJ A;  456C A;  1Q3A A;  5D2B A;  1KBC A;  4AUO A;  1JKY A;  5I2Z A;  3USN A;  3RTT A;  3OHO A;  3LQ0 A;  3E8R A;  1G4K A;  1AKL A;  1YP1 A;  2K9C A;  3EDZ A;  1XFW A;  1BKC E;  2D1N A;  1GO8 P;  2W15 A;  1Y0V A;  2OW9 A;  3LMC A;  2YUF A;  4ILW D;  2WO9 A;  3P24 A;  5I3M A;  4FVL A;  2OVX A;  1OM6 A;  4Q1L A;  1OS2 A;  1HTD A;  4WZV A;  2DW0 A;  2FV9 A;  1I73 A;  1FM1 A;  1ROS A;  1JAN A;  1B8Y A;  2E2D A;  4H3X A;  2TCL A;  2J0T A;  1YOU A;  1CGE A;  3L0T A;  2OW2 A;  1KUI A;  4DF9 A;  2A8H A;  4L19 A;  3LIL A;  1R1J A;  1Z3J A;  3VTG A;  4H49 A;  1G49 A;  4CTH A;  1IAB A;  1KUK A;  2FV5 A;  3LE9 A;  1QUA A;  2YIG A;  3LGP A;  5I12 A;  2E3X A;  1PWW A;  1XUD A;  3HDA P;  1B3D A;  3HBV P;  4GWM A;  1GO7 P;  5BOT A;  4XM7 A;  4XBH A;  1SRP A;  2XS3 A;  4PKS A;  4FXY P;  3HBU P;  1I76 A;  4G0D A;  5JMY A;  2N8R A;  4IN9 A;  1KAP P;  3LJG A;  1BIW A;  2JSD A;  1BQQ M;  3U1R A;  4A3W A;  1JAP A;  1CIZ A;  3HB2 P;  1C3I A;  2DDF A;  1JH1 A;  1ZS0 A;  2CLT A;  2WOA A;  5D1T A;  3WV3 A;  3F1A A;  5H8X A;  2SRT A;  1ZXC A;  3CKI A;  3RTS A;  1PWU A;  1J7N A;  3GBO A;  4XCT A;  2OXU A;  1K7I A;  3EHX A;  2W14 A;  3N2V A;  3B2Z A;  4GF1 A;  2RJQ A;  2DDY A;  1CK7 A;  4JQG A;  4IJO A;  1DMT A;  1JK3 A;  1MMB A;  1PWP A;  1D7X A;  1KUF A;  2V4B A;  2WO8 A;  1QIB A;  2W13 A;  4DPE A;  1BM6 A;  3G5C A;  1IAC A;  4L7A A;  1JAO A;  2JNP A;  4JP4 A;  3F18 A;  1CAQ A;  3LJT A;  2Z2D A;  5D1U A;  3ZXH A;  2XS4 A;  1BSW A;  1SU3 A;  4PKQ A;  1ND1 A;  1SLN A;  1R1I A;  4AXQ A;  3ELM A;  4DV8 A;  1MMQ A;  4G9L A;  3WV1 A;  1EUB A;  3F16 A;  4H76 A;  2POJ A;  2CKI A;  1IAG A;  4PKT A;  1ZTQ A;  1RM8 A;  3SHI A;  3LIR A;  1YQY A;  2USN A;  3UVC A;  2X3C A;  1FBL A;  3HYG A;  4ON1 A;  2MZE A;  1R54 A;  1CGF A;  3LUN A;  1S4B P;  3F19 A;  2ERO A;  1GXD A;  4GR3 A;  1K7Q A;  1JJ9 A;  1XFZ A;  2ERP A;  3LJZ A;  3AYU A;  1BKC A;  2MZI A;  1XFX A;  4EFS A;  2MLS A;  1OM8 A;  1GE7 A;  4L6T A;  4GR0 A;  2ERQ A;  1G05 A;  2J83 A;  4H1Q A;  1XAX A;  1ZP5 A;  3K7N A;  3DSL A;  4GR8 A;  1UMT A;  3KME A;  1QJI A;  3KEC A;  4I03 A;  1BUD A;  3KRY A;  1UEA A;  3DTK A;  2O36 A;  4XM8 A;  1K7G A;  2YB9 A;  3G42 A;  3AYK A;  2O3E A;  1USN A;  2OZR A;  1UTZ A;  2JT6 A;  2OW0 A;  1HY7 A;  3HDB A;  3KMC A;  1MNC A;  1YCM A;  1C8T A;  2RJP A;  2OXW A;  4J4M A;  4H84 A;  5BOY A;  3EDI A;  3DWB A;  3HY9 A;  3F17 A;  2W12 A;  2OW1 A;  1D5J A;  4L63 A;  3EWJ A;  1I1I P;  1HFS A;  2D1O A; 
#chains in the Genus database with same CATH homology
 2OY2 A;  2K2G A;  2JIH A;  1OS9 A;  5D3C A;  1A86 A;  2KRJ A;  5CZM A;  1AYK A;  1CQR A;  5D7W A;  2OVZ A;  1AST A;  5CXA A;  1XUC A;  1XUR A;  2L0R A;  4ZR5 A;  3BA0 A;  1QIC A;  3VI1 A;  1CXV A;  1IAA A;  1SLM A;  1ZVX A;  4AYK A;  3V96 B;  2X3B A;  3LKA A;  5B5P A;  1XFU A;  1GKC A;  1HOV A;  1IAD A;  2MZH A;  4A7B A;  1OMJ A;  5D1S A;  1ATL A;  3K7L A;  3L0V A;  3I7I A;  3TSK A;  1R1H A;  1ZXV A;  2OY4 A;  1A85 A;  4H30 A;  2DW2 A;  1FLS A;  3LEA A;  4WK7 A;  3EDG A;  3NX7 A;  4WKI A;  1JIW P;  1JAQ A;  3Q2G A;  3ZUK A;  4HX3 A;  5CUH A;  3WV2 A;  4JPA A;  3TT4 A;  4DD8 A;  1AF0 A;  3P1V A;  1BUV M;  3B8Z A;  3DTE A;  4PKU A;  1GKD A;  4GQL A;  5LAB A;  3I7G A;  1IAE A;  3OHL A;  5B5O A;  5L7F A;  2AIG P;  3LQB A;  1G12 A;  1HV5 A;  3DTI A;  3KEJ A;  4AIG A;  1XFV A;  1GE6 A;  1Y93 A;  2MLR A;  1OM7 A;  3HY7 A;  5L79 A;  3B92 A;  2OI0 A;  3KHI A;  2HU6 A;  4FU4 A;  3LK8 A;  4JIJ A;  1L6J A;  1SAT A;  4PKV A;  3ZVS A;  3Q2H A;  4HMA A;  1DTH A;  1PWV A;  1KUH A;  1UMS A;  4QKZ A;  1QJJ A;  1RMZ A;  1GE5 A;  2I47 A;  2JT5 A;  3TVC A;  2DW1 A;  2Y6D A;  1O0T A;  5I43 A;  1KUG A;  2PJT A;  1G9K A;  3AIG A;  3LUM A;  4I35 A;  1EAK A;  4H2E A;  1MMP A;  1R55 A;  1QIA A;  5BPA A;  1CGL A;  4GWN A;  4IUW A;  1WNI A;  1OO9 A;  4R3V A;  1MMR A;  3TS4 A;  3DPE A;  1D8F A;  3DL1 A;  5I4O A;  830C A;  3LIK A;  966C A;  2W0D A;  4H82 A;  5I0L A;  2Y6C A;  1BZS A;  3EDH A;  1O0Q A;  2AYK A;  4PKW A;  2OXZ A;  2X3A A;  1BQO A;  4XM6 A;  4WKE A;  1SMP A;  4FXQ A;  4WF6 A;  1H71 P;  3EHY A;  1JIZ A;  4PKR A;  3O64 A;  4GUY A;  3DNG A;  1HFC A;  1PWQ A;  2X7M A;  4JA1 A;  3KWV C;  3F15 A;  3MA2 A;  1BKC I;  1UTT A;  3KEK A;  1EB6 A;  3O2X A;  3N2U A;  1XFY A;  1C7K A;  3DPF A;  1Y8J A;  1D8M A;  2QPJ A;  456C A;  1Q3A A;  5D2B A;  1KBC A;  4AUO A;  1JKY A;  5I2Z A;  3USN A;  3RTT A;  3OHO A;  3LQ0 A;  3E8R A;  1G4K A;  1AKL A;  1YP1 A;  2K9C A;  3EDZ A;  1XFW A;  1BKC E;  2D1N A;  1GO8 P;  2W15 A;  1Y0V A;  2OW9 A;  3LMC A;  2YUF A;  4ILW D;  2WO9 A;  3P24 A;  5I3M A;  4FVL A;  2OVX A;  1OM6 A;  4Q1L A;  1OS2 A;  1HTD A;  4WZV A;  2DW0 A;  2FV9 A;  1I73 A;  1FM1 A;  1ROS A;  1JAN A;  1B8Y A;  2E2D A;  4H3X A;  2TCL A;  2J0T A;  1YOU A;  1CGE A;  3L0T A;  2OW2 A;  1KUI A;  4DF9 A;  2A8H A;  4L19 A;  3LIL A;  1R1J A;  1Z3J A;  3VTG A;  4H49 A;  1G49 A;  4CTH A;  1IAB A;  1KUK A;  2FV5 A;  3LE9 A;  1QUA A;  2YIG A;  3LGP A;  5I12 A;  2E3X A;  1PWW A;  1XUD A;  3HDA P;  1B3D A;  3HBV P;  4GWM A;  1GO7 P;  5BOT A;  4XM7 A;  4XBH A;  1SRP A;  2XS3 A;  4PKS A;  4FXY P;  3HBU P;  1I76 A;  4G0D A;  5JMY A;  2N8R A;  4IN9 A;  1KAP P;  3LJG A;  1BIW A;  2JSD A;  1BQQ M;  3U1R A;  4A3W A;  1JAP A;  1CIZ A;  3HB2 P;  1C3I A;  2DDF A;  1JH1 A;  1ZS0 A;  2CLT A;  2WOA A;  5D1T A;  3WV3 A;  3F1A A;  5H8X A;  2SRT A;  1ZXC A;  3CKI A;  3RTS A;  1PWU A;  1J7N A;  3GBO A;  4XCT A;  2OXU A;  1K7I A;  3EHX A;  2W14 A;  3N2V A;  3B2Z A;  4GF1 A;  2RJQ A;  2DDY A;  1CK7 A;  4JQG A;  4IJO A;  1DMT A;  1JK3 A;  1MMB A;  1PWP A;  1D7X A;  1KUF A;  2V4B A;  2WO8 A;  1QIB A;  2W13 A;  4DPE A;  1BM6 A;  3G5C A;  1IAC A;  4L7A A;  1JAO A;  2JNP A;  4JP4 A;  3F18 A;  1CAQ A;  3LJT A;  2Z2D A;  5D1U A;  3ZXH A;  2XS4 A;  1BSW A;  1SU3 A;  4PKQ A;  1ND1 A;  1SLN A;  1R1I A;  4AXQ A;  3ELM A;  4DV8 A;  1MMQ A;  4G9L A;  3WV1 A;  1EUB A;  3F16 A;  4H76 A;  2POJ A;  2CKI A;  1IAG A;  4PKT A;  1ZTQ A;  1RM8 A;  3SHI A;  3LIR A;  1YQY A;  2USN A;  3UVC A;  2X3C A;  1FBL A;  3HYG A;  4ON1 A;  2MZE A;  1R54 A;  1CGF A;  3LUN A;  1S4B P;  3F19 A;  2ERO A;  1GXD A;  4GR3 A;  1K7Q A;  1JJ9 A;  1XFZ A;  2ERP A;  3LJZ A;  3AYU A;  1BKC A;  2MZI A;  1XFX A;  4EFS A;  2MLS A;  1OM8 A;  1GE7 A;  4L6T A;  4GR0 A;  2ERQ A;  1G05 A;  2J83 A;  4H1Q A;  1ZP5 A;  3K7N A;  3DSL A;  4GR8 A;  1UMT A;  3KME A;  1QJI A;  3KEC A;  4I03 A;  1BUD A;  3KRY A;  1UEA A;  3DTK A;  2O36 A;  4XM8 A;  1K7G A;  2YB9 A;  3G42 A;  3AYK A;  2O3E A;  1USN A;  2OZR A;  1UTZ A;  2JT6 A;  2OW0 A;  1HY7 A;  3HDB A;  3KMC A;  1MNC A;  1YCM A;  1C8T A;  2RJP A;  2OXW A;  4J4M A;  4H84 A;  5BOY A;  3EDI A;  3DWB A;  3HY9 A;  3F17 A;  2W12 A;  2OW1 A;  1D5J A;  4L63 A;  3EWJ A;  1I1I P;  1HFS A;  2D1O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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