1JAQA

Complex of 1-hydroxylamine-2-isobutylmalonyl-ala-gly-nh2 with the catalytic domain of matrix metallo proteinase-8 (met80 form)
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
158
structure length
158
Chain Sequence
NPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords MATRIX METALLO PROTEINASE-8 (MET80 FORM)
total genus 43
structure length 158
sequence length 158
ec nomenclature ec 3.4.24.34: Neutrophil collagenase.
pdb deposition date 1996-03-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1jaqA00
1EUBA 456CA 5D7WA 1BM6A 2L0RA 3UVCA 2FV5A 3DPFA 3G42A 3B2ZA 1D5JA 1RM8A 2MZEA 4XM8A 3L0TA 2OW1A 3DSLA 4H1QA 4JQGA 3B8ZA 1G9KA 4FVLA 4QKZA 4FXYP 2OW9A 3O2XA 4GF1A 2V4BA 2J83A 4AYKA 1KUIA 2OY4A 2MZHA 1MMRA 5I12A 3F1AA 1SU3A 3LK8A 2XS3A 1BIWA 4PKWA 1R54A 3LQBA 1GKCA 3HBVP 4AUOA 1D8FA 4AXQA 1CQRA 1Q3AA 5CZMA 3K7NA 3GBOA 1QICA 3EDZA 1ZP5A 1GE7A 3LMCA 4WKEA 2FV9A 4H49A 2JNPA 5I4OA 1JKYA 3HDAP 1OM6A 3K7LA 2W14A 2POJA 3LJZA 3MA2A 1CGLA 4I35A 1QUAA 3LE9A 4IN9A 2JIHA 1A85A 1ROSA 2D1NA 1AKLA 5I43A 2XS4A 3EHYA 3KECA 1C3IA 2AYKA 2Z2DA 1IAAA 1R1HA 1OS9A 5LABA 1XFYA 2Y6DA 3B92A 4A3WA 2N8RA 3ELMA 1BZSA 1JJ9A 1HY7A 1SLNA 4H82A 4DD8A 3ZXHA 1G05A 3Q2GA 1PWUA 2JT5A 2OVXA 2X7MA 1USNA 2OXUA 5D2BA 4L19A 3ZUKA 1SMPA 3RTSA 3SHIA 1Y0VA 4DF9A 1OM8A 1FLSA 2O3EA 3U1RA 2TCLA 2WO9A 4DV8A 3LGPA 4ON1A 4GR3A 1ATLA 5L7FA 1XFVA 1FM1A 3LQ0A 3VI1A 3HYGA 2OW2A 4JP4A 3DNGA 4GWMA 1I76A 1UEAA 3HBUP 3BA0A 1DTHA 4WF6A 3E8RA 4JPAA 1XFXA 2X3AA 4A7BA 1ZTQA 2AIGP 3N2VA 2K2GA 5I0LA 2OVZA 1JK3A 1HFCA 2O36A 2OZRA 1CAQA 1G49A 1GO7P 3LIRA 3TSKA 1EAKA 4GQLA 3NX7A 1BKCE 2MLSA 3WV2A 1GXDA 3LUNA 3EWJA 4EFSA 3I7IA 1GE6A 2DDYA 3LEAA 3WV1A 3HY9A 830CA 1HFSA 3N2UA 1KUKA 4GWNA 1D7XA 3F19A 2ERPA 1GKDA 3V96B 1HV5A 3AYUA 3F15A 4PKVA 4J4MA 1QJIA 2KRJA 1O0QA 1QIAA 4GR0A 4ILWD 1R1IA 2A8HA 1KAPP 1BKCA 1IADA 3HDBA 1AYKA 1IAEA 3KRYA 3TS4A 2E2DA 3CKIA 2OXWA 1K7IA 2WO8A 1RMZA 3LKAA 2J0TA 2SRTA 1XURA 3KMCA 2JT6A 2OW0A 1Y93A 1EB6A 1FBLA 2K9CA 1PWPA 1JAPA 4XM7A 1ND1A 3ZVSA 2DW2A 5CUHA 5BOYA 1SATA 4PKQA 3OHLA 4JIJA 1XFUA 2QPJA 1GE5A 4H84A 2W13A 4H2EA 4H30A 1YP1A 3TVCA 5BOTA 1D8MA 2W15A 2MZIA 4WK7A 1C8TA 4Q1LA 4CTHA 3LIKA 1JANA 1CXVA 4R3VA 1BSWA 2HU6A 4XBHA 2ERQA 2JSDA 1CGFA 1O0TA 3F16A 3EDGA 2E3XA 5BPAA 2MLRA 1I1IP 2D1OA 1OO9A 2OI0A 1AF0A 1CK7A 3VTGA 4G9LA 3I7GA 3KEKA 3P24A 1G12A 3LJGA 1IAGA 5D1UA 2WOAA 1K7QA 1UTZA 1BQOA 3L0VA 4XCTA 2CKIA 1YOUA 1JIWP 3WV3A 1K7GA 4H3XA 5H8XA 1GO8P 4WZVA 1R1JA 2Y6CA 1BQQM 1JAOA 1QJJA 4PKTA 5B5PA 1JIZA 4PKUA 3P1VA 5L79A 5D3CA 4GR8A 1IACA 1KUHA 3G5CA 4JA1A 3EHXA 1UMTA 2DW1A 2DW0A 3F17A 3KHIA 1UTTA 1H71P 1YCMA 3DWBA 4PKRA 1KUFA 2YB9A 1MMBA 1ASTA 1J7NA 3HY7A 5CXAA 1HTDA 4IJOA 4PKSA 1CIZA 1BUVM 3RTTA 1MMPA 4L6TA 4IUWA 1ZXVA 3EDHA 1B8YA 2X3BA 1ZVXA 2I47A 1XUDA 1Y8JA 2YIGA 2RJPA 5I2ZA 4GUYA 1SLMA 1CGEA 1OMJA 2RJQA 1HOVA 2OXZA 4HMAA 1KBCA 4FU4A 3AYKA 3HB2P 1OM7A 4XM6A 3DPEA 5D1TA 4DPEA 1XFZA 4AIGA 5B5OA 5JMYA 1BUDA 4H76A 1ZS0A 4HX3A 1DMTA 1PWWA 1S4BP 1PWQA 1SRPA 1JH1A 4WKIA 1MNCA 2X3CA 1ZXCA 3O64A 1XUCA 1IABA 4FXQA 1YQYA 3DL1A 966CA 3LILA 2EROA 3KEJA 1WNIA 5I3MA 3Q2HA 3F18A 1Z3JA 3KWVC 3USNA 1A86A 2W0DA 2OY2A 1JAQA 1BKCI 1OS2A 1KUGA 4ZR5A 1I73A 1MMQA 3EDIA 3AIGA 2USNA 4L63A 1C7KA 1R55A 1XFWA 1QIBA 1G4KA 1B3DA 3OHOA 1PWVA 1UMSA 2W12A 2DDFA 4I03A 3KMEA 4G0DA 3LUMA 3LJTA 2PJTA 5D1SA 2CLTA 1L6JA 3TT4A
chains in the Genus database with same CATH superfamily
1EUBA 456CA 5D7WA 1BM6A 2L0RA 3UVCA 2FV5A 3DPFA 3G42A 3B2ZA 1D5JA 1RM8A 2MZEA 4XM8A 3L0TA 4L7AA 2OW1A 3DSLA 4H1QA 4JQGA 3B8ZA 1G9KA 4FVLA 4QKZA 4FXYP 2OW9A 3O2XA 4GF1A 2V4BA 2J83A 4AYKA 1KUIA 2OY4A 2MZHA 1MMRA 1XAXA 5I12A 3F1AA 1SU3A 3LK8A 2XS3A 1BIWA 4PKWA 1R54A 3LQBA 1GKCA 3HBVP 4AUOA 1D8FA 4AXQA 1CQRA 1Q3AA 5CZMA 3K7NA 3GBOA 1QICA 3EDZA 1ZP5A 1GE7A 3LMCA 4WKEA 2FV9A 4H49A 2JNPA 5I4OA 1JKYA 3HDAP 1OM6A 3K7LA 2W14A 2POJA 3LJZA 3MA2A 1CGLA 4I35A 1QUAA 3LE9A 4IN9A 2JIHA 1A85A 1ROSA 2D1NA 1AKLA 5I43A 2XS4A 3EHYA 3KECA 1C3IA 2AYKA 2Z2DA 1IAAA 1R1HA 1OS9A 5LABA 1XFYA 2Y6DA 3B92A 4A3WA 2N8RA 3ELMA 1BZSA 1JJ9A 1HY7A 1SLNA 4H82A 4DD8A 3ZXHA 1G05A 3Q2GA 1PWUA 2JT5A 2OVXA 2X7MA 1USNA 2OXUA 5D2BA 4L19A 3ZUKA 1SMPA 3RTSA 3SHIA 1Y0VA 4DF9A 1OM8A 1FLSA 2O3EA 3U1RA 2TCLA 1TVIA 2WO9A 4DV8A 3LGPA 4ON1A 4GR3A 1ATLA 5L7FA 1XFVA 1FM1A 3LQ0A 3VI1A 3HYGA 2OW2A 4JP4A 3DNGA 4GWMA 1I76A 1UEAA 3HBUP 3DTIA 3BA0A 1DTHA 4WF6A 3E8RA 4JPAA 1XFXA 2X3AA 4A7BA 1ZTQA 2AIGP 3N2VA 2K2GA 5I0LA 2OVZA 1JK3A 1HFCA 2O36A 2OZRA 1CAQA 1G49A 1GO7P 3LIRA 3TSKA 1EAKA 4GQLA 3NX7A 1BKCE 2MLSA 3WV2A 1GXDA 3LUNA 3EWJA 4EFSA 3I7IA 1GE6A 2DDYA 3LEAA 3WV1A 3HY9A 830CA 1HFSA 3N2UA 1KUKA 4GWNA 1D7XA 3F19A 2ERPA 1GKDA 3V96B 1HV5A 3AYUA 3F15A 4PKVA 4J4MA 1QJIA 2KRJA 1O0QA 1QIAA 4GR0A 4ILWD 1R1IA 2A8HA 1KAPP 1BKCA 1IADA 3HDBA 1AYKA 1IAEA 3KRYA 3TS4A 2E2DA 3CKIA 2OXWA 1K7IA 2WO8A 1RMZA 3LKAA 2J0TA 2SRTA 1XURA 3KMCA 2JT6A 2OW0A 1Y93A 1EB6A 1FBLA 2K9CA 1PWPA 1JAPA 4XM7A 1ND1A 3ZVSA 2DW2A 5CUHA 5BOYA 3DTKA 1SATA 4PKQA 3OHLA 4JIJA 1XFUA 2QPJA 1GE5A 4H84A 2W13A 4H2EA 4H30A 1YP1A 3TVCA 5BOTA 1D8MA 2W15A 2MZIA 4WK7A 1C8TA 4Q1LA 4CTHA 3LIKA 1JANA 1CXVA 4R3VA 1BSWA 2HU6A 4XBHA 2ERQA 2JSDA 1CGFA 1O0TA 1XM5A 3DTEA 3F16A 3EDGA 2E3XA 5BPAA 2MLRA 1I1IP 2D1OA 1OO9A 2OI0A 1AF0A 1CK7A 3VTGA 4G9LA 3I7GA 3KEKA 3P24A 1G12A 3LJGA 1IAGA 5D1UA 2WOAA 1K7QA 1UTZA 1BQOA 3L0VA 4XCTA 2CKIA 1YOUA 1JIWP 3WV3A 1K7GA 4H3XA 5H8XA 1GO8P 4WZVA 1R1JA 2Y6CA 1BQQM 1JAOA 1QJJA 4PKTA 5B5PA 1JIZA 4PKUA 3P1VA 5L79A 5D3CA 4GR8A 1IACA 1KUHA 3G5CA 4JA1A 3EHXA 1UMTA 2DW1A 2DW0A 3F17A 3KHIA 1UTTA 1H71P 1YCMA 3DWBA 4PKRA 1KUFA 2YB9A 1MMBA 1ASTA 1J7NA 3HY7A 5CXAA 1HTDA 4IJOA 4PKSA 1CIZA 1BUVM 3RTTA 1MMPA 4L6TA 4IUWA 1ZXVA 3EDHA 1B8YA 2X3BA 1ZVXA 2I47A 1XUDA 1Y8JA 2YIGA 2RJPA 5I2ZA 4GUYA 1SLMA 1CGEA 1OMJA 2RJQA 1HOVA 2OXZA 4HMAA 1KBCA 4FU4A 3AYKA 3HB2P 1OM7A 4XM6A 3DPEA 5D1TA 4DPEA 1XFZA 4AIGA 5B5OA 5JMYA 1BUDA 4H76A 1ZS0A 4HX3A 1DMTA 1PWWA 1S4BP 1PWQA 1SRPA 2YUFA 1JH1A 4WKIA 1MNCA 2X3CA 1ZXCA 3O64A 1XUCA 1IABA 4FXQA 1YQYA 3DL1A 966CA 3LILA 2EROA 3KEJA 1WNIA 5I3MA 3Q2HA 3F18A 1Z3JA 3KWVC 3USNA 1A86A 2W0DA 2OY2A 1JAQA 1BKCI 1OS2A 1KUGA 4ZR5A 1I73A 1MMQA 3EDIA 3AIGA 2USNA 4L63A 1C7KA 1R55A 1XFWA 1QIBA 1G4KA 1B3DA 3OHOA 1PWVA 1UMSA 2W12A 2DDFA 4I03A 3KMEA 4G0DA 3LUMA 1OZ9A 3LJTA 2PJTA 5D1SA 2CLTA 1L6JA 3TT4A
chains in the Genus database with same CATH topology
1EUBA 456CA 5D7WA 1BM6A 2L0RA 3UVCA 2FV5A 3DPFA 3G42A 3B2ZA 1D5JA 1RM8A 2MZEA 4XM8A 3L0TA 4L7AA 2OW1A 3DSLA 4H1QA 4JQGA 3B8ZA 1G9KA 4FVLA 4QKZA 4FXYP 2OW9A 3O2XA 4GF1A 2V4BA 2J83A 4AYKA 1KUIA 2OY4A 2MZHA 1MMRA 5I12A 3F1AA 1SU3A 3LK8A 2XS3A 1BIWA 4PKWA 1R54A 3LQBA 1GKCA 3HBVP 4AUOA 1D8FA 4AXQA 1CQRA 1Q3AA 5CZMA 3K7NA 3GBOA 1QICA 3EDZA 1ZP5A 1GE7A 3LMCA 4WKEA 2FV9A 4H49A 2JNPA 5I4OA 1JKYA 3HDAP 1OM6A 3K7LA 2W14A 2POJA 3LJZA 3MA2A 1CGLA 4I35A 1QUAA 3LE9A 4IN9A 2JIHA 1A85A 1ROSA 2D1NA 1AKLA 5I43A 2XS4A 3EHYA 3KECA 1C3IA 2AYKA 2Z2DA 1IAAA 1R1HA 1OS9A 5LABA 1XFYA 2Y6DA 3B92A 4A3WA 2N8RA 3ELMA 1BZSA 1JJ9A 1HY7A 1SLNA 4H82A 4DD8A 3ZXHA 1G05A 3Q2GA 1PWUA 2JT5A 2OVXA 2X7MA 1USNA 2OXUA 5D2BA 4L19A 3ZUKA 1SMPA 3RTSA 3SHIA 1Y0VA 4DF9A 1OM8A 1FLSA 2O3EA 3U1RA 2TCLA 2WO9A 4DV8A 3LGPA 4ON1A 4GR3A 1ATLA 5L7FA 1XFVA 1FM1A 3LQ0A 3VI1A 3HYGA 2OW2A 4JP4A 3DNGA 4GWMA 1I76A 1UEAA 3HBUP 3DTIA 3BA0A 1DTHA 4WF6A 3E8RA 4JPAA 1XFXA 2X3AA 4A7BA 1ZTQA 2AIGP 3N2VA 2K2GA 5I0LA 2OVZA 1JK3A 1HFCA 2O36A 2OZRA 1CAQA 1G49A 1GO7P 3LIRA 3TSKA 1EAKA 4GQLA 3NX7A 1BKCE 2MLSA 3WV2A 1GXDA 3LUNA 3EWJA 4EFSA 3I7IA 1GE6A 2DDYA 3LEAA 3WV1A 3HY9A 830CA 1HFSA 3N2UA 1KUKA 4GWNA 1D7XA 3F19A 2ERPA 1GKDA 3V96B 1HV5A 3AYUA 3F15A 4PKVA 4J4MA 1QJIA 2KRJA 1O0QA 1QIAA 4GR0A 4ILWD 1R1IA 2A8HA 1KAPP 1BKCA 1IADA 3HDBA 1AYKA 1IAEA 3KRYA 3TS4A 2E2DA 3CKIA 2OXWA 1K7IA 2WO8A 1RMZA 3LKAA 2J0TA 2SRTA 1XURA 3KMCA 2JT6A 2OW0A 1Y93A 1EB6A 1FBLA 2K9CA 1PWPA 1JAPA 4XM7A 1ND1A 3ZVSA 2DW2A 5CUHA 5BOYA 3DTKA 1SATA 4PKQA 3OHLA 4JIJA 1XFUA 2QPJA 1GE5A 4H84A 2W13A 4H2EA 4H30A 1YP1A 3TVCA 5BOTA 1D8MA 2W15A 2MZIA 4WK7A 1C8TA 4Q1LA 4CTHA 3LIKA 1JANA 1CXVA 4R3VA 1BSWA 2HU6A 4XBHA 2ERQA 2JSDA 1CGFA 1O0TA 3DTEA 3F16A 3EDGA 2E3XA 5BPAA 2MLRA 1I1IP 2D1OA 1OO9A 2OI0A 1AF0A 1CK7A 3VTGA 4G9LA 3I7GA 3KEKA 3P24A 1G12A 3LJGA 1IAGA 5D1UA 2WOAA 1K7QA 1UTZA 1BQOA 3L0VA 4XCTA 2CKIA 1YOUA 1JIWP 3WV3A 1K7GA 4H3XA 5H8XA 1GO8P 4WZVA 1R1JA 2Y6CA 1BQQM 1JAOA 1QJJA 4PKTA 5B5PA 1JIZA 4PKUA 3P1VA 5L79A 5D3CA 4GR8A 1IACA 1KUHA 3G5CA 4JA1A 3EHXA 1UMTA 2DW1A 2DW0A 3F17A 3KHIA 1UTTA 1H71P 1YCMA 3DWBA 4PKRA 1KUFA 2YB9A 1MMBA 1ASTA 1J7NA 3HY7A 5CXAA 1HTDA 4IJOA 4PKSA 1CIZA 1BUVM 3RTTA 1MMPA 4L6TA 4IUWA 1ZXVA 3EDHA 1B8YA 2X3BA 1ZVXA 2I47A 1XUDA 1Y8JA 2YIGA 2RJPA 5I2ZA 4GUYA 1SLMA 1CGEA 1OMJA 2RJQA 1HOVA 2OXZA 4HMAA 1KBCA 4FU4A 3AYKA 3HB2P 1OM7A 4XM6A 3DPEA 5D1TA 4DPEA 1XFZA 4AIGA 5B5OA 5JMYA 1BUDA 4H76A 1ZS0A 4HX3A 1DMTA 1PWWA 1S4BP 1PWQA 1SRPA 2YUFA 1JH1A 4WKIA 1MNCA 2X3CA 1ZXCA 3O64A 1XUCA 1IABA 4FXQA 1YQYA 3DL1A 966CA 3LILA 2EROA 3KEJA 1WNIA 5I3MA 3Q2HA 3F18A 1Z3JA 3KWVC 3USNA 1A86A 2W0DA 2OY2A 1JAQA 1BKCI 1OS2A 1KUGA 4ZR5A 1I73A 1MMQA 3EDIA 3AIGA 2USNA 4L63A 1C7KA 1R55A 1XFWA 1QIBA 1G4KA 1B3DA 3OHOA 1PWVA 1UMSA 2W12A 2DDFA 4I03A 3KMEA 4G0DA 3LUMA 3LJTA 2PJTA 5D1SA 2CLTA 1L6JA 3TT4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EUB A;  456C A;  5D7W A;  1BM6 A;  2L0R A;  3UVC A;  2FV5 A;  3DPF A;  3G42 A;  3B2Z A;  1D5J A;  1RM8 A;  2MZE A;  4XM8 A;  3L0T A;  2OW1 A;  3DSL A;  4H1Q A;  4JQG A;  3B8Z A;  1G9K A;  4FVL A;  4QKZ A;  4FXY P;  2OW9 A;  3O2X A;  4GF1 A;  2V4B A;  2J83 A;  4AYK A;  1KUI A;  2OY4 A;  2MZH A;  1MMR A;  5I12 A;  3F1A A;  1SU3 A;  3LK8 A;  2XS3 A;  1BIW A;  4PKW A;  1R54 A;  3LQB A;  1GKC A;  3HBV P;  4AUO A;  1D8F A;  4AXQ A;  1CQR A;  1Q3A A;  5CZM A;  3K7N A;  3GBO A;  1QIC A;  3EDZ A;  1ZP5 A;  1GE7 A;  3LMC A;  4WKE A;  2FV9 A;  4H49 A;  2JNP A;  5I4O A;  1JKY A;  3HDA P;  1OM6 A;  3K7L A;  2W14 A;  2POJ A;  3LJZ A;  3MA2 A;  1CGL A;  4I35 A;  1QUA A;  3LE9 A;  4IN9 A;  2JIH A;  1A85 A;  1ROS A;  2D1N A;  1AKL A;  5I43 A;  2XS4 A;  3EHY A;  3KEC A;  1C3I A;  2AYK A;  2Z2D A;  1IAA A;  1R1H A;  1OS9 A;  5LAB A;  1XFY A;  2Y6D A;  3B92 A;  4A3W A;  2N8R A;  3ELM A;  1BZS A;  1JJ9 A;  1HY7 A;  1SLN A;  4H82 A;  4DD8 A;  3ZXH A;  1G05 A;  3Q2G A;  1PWU A;  2JT5 A;  2OVX A;  2X7M A;  1USN A;  2OXU A;  5D2B A;  4L19 A;  3ZUK A;  1SMP A;  3RTS A;  3SHI A;  1Y0V A;  4DF9 A;  1OM8 A;  1FLS A;  2O3E A;  3U1R A;  2TCL A;  2WO9 A;  4DV8 A;  3LGP A;  4ON1 A;  4GR3 A;  1ATL A;  5L7F A;  1XFV A;  1FM1 A;  3LQ0 A;  3VI1 A;  3HYG A;  2OW2 A;  4JP4 A;  3DNG A;  4GWM A;  1I76 A;  1UEA A;  3HBU P;  3BA0 A;  1DTH A;  4WF6 A;  3E8R A;  4JPA A;  1XFX A;  2X3A A;  4A7B A;  1ZTQ A;  2AIG P;  3N2V A;  2K2G A;  5I0L A;  2OVZ A;  1JK3 A;  1HFC A;  2O36 A;  2OZR A;  1CAQ A;  1G49 A;  1GO7 P;  3LIR A;  3TSK A;  1EAK A;  4GQL A;  3NX7 A;  1BKC E;  2MLS A;  3WV2 A;  1GXD A;  3LUN A;  3EWJ A;  4EFS A;  3I7I A;  1GE6 A;  2DDY A;  3LEA A;  3WV1 A;  3HY9 A;  830C A;  1HFS A;  3N2U A;  1KUK A;  4GWN A;  1D7X A;  3F19 A;  2ERP A;  1GKD A;  3V96 B;  1HV5 A;  3AYU A;  3F15 A;  4PKV A;  4J4M A;  1QJI A;  2KRJ A;  1O0Q A;  1QIA A;  4GR0 A;  4ILW D;  1R1I A;  2A8H A;  1KAP P;  1BKC A;  1IAD A;  3HDB A;  1AYK A;  1IAE A;  3KRY A;  3TS4 A;  2E2D A;  3CKI A;  2OXW A;  1K7I A;  2WO8 A;  1RMZ A;  3LKA A;  2J0T A;  2SRT A;  1XUR A;  3KMC A;  2JT6 A;  2OW0 A;  1Y93 A;  1EB6 A;  1FBL A;  2K9C A;  1PWP A;  1JAP A;  4XM7 A;  1ND1 A;  3ZVS A;  2DW2 A;  5CUH A;  5BOY A;  1SAT A;  4PKQ A;  3OHL A;  4JIJ A;  1XFU A;  2QPJ A;  1GE5 A;  4H84 A;  2W13 A;  4H2E A;  4H30 A;  1YP1 A;  3TVC A;  5BOT A;  1D8M A;  2W15 A;  2MZI A;  4WK7 A;  1C8T A;  4Q1L A;  4CTH A;  3LIK A;  1JAN A;  1CXV A;  4R3V A;  1BSW A;  2HU6 A;  4XBH A;  2ERQ A;  2JSD A;  1CGF A;  1O0T A;  3F16 A;  3EDG A;  2E3X A;  5BPA A;  2MLR A;  1I1I P;  2D1O A;  1OO9 A;  2OI0 A;  1AF0 A;  1CK7 A;  3VTG A;  4G9L A;  3I7G A;  3KEK A;  3P24 A;  1G12 A;  3LJG A;  1IAG A;  5D1U A;  2WOA A;  1K7Q A;  1UTZ A;  1BQO A;  3L0V A;  4XCT A;  2CKI A;  1YOU A;  1JIW P;  3WV3 A;  1K7G A;  4H3X A;  5H8X A;  1GO8 P;  4WZV A;  1R1J A;  2Y6C A;  1BQQ M;  1JAO A;  1QJJ A;  4PKT A;  5B5P A;  1JIZ A;  4PKU A;  3P1V A;  5L79 A;  5D3C A;  4GR8 A;  1IAC A;  1KUH A;  3G5C A;  4JA1 A;  3EHX A;  1UMT A;  2DW1 A;  2DW0 A;  3F17 A;  3KHI A;  1UTT A;  1H71 P;  1YCM A;  3DWB A;  4PKR A;  1KUF A;  2YB9 A;  1MMB A;  1AST A;  1J7N A;  3HY7 A;  5CXA A;  1HTD A;  4IJO A;  4PKS A;  1CIZ A;  1BUV M;  3RTT A;  1MMP A;  4L6T A;  4IUW A;  1ZXV A;  3EDH A;  1B8Y A;  2X3B A;  1ZVX A;  2I47 A;  1XUD A;  1Y8J A;  2YIG A;  2RJP A;  5I2Z A;  4GUY A;  1SLM A;  1CGE A;  1OMJ A;  2RJQ A;  1HOV A;  2OXZ A;  4HMA A;  1KBC A;  4FU4 A;  3AYK A;  3HB2 P;  1OM7 A;  4XM6 A;  3DPE A;  5D1T A;  4DPE A;  1XFZ A;  4AIG A;  5B5O A;  5JMY A;  1BUD A;  4H76 A;  1ZS0 A;  4HX3 A;  1DMT A;  1PWW A;  1S4B P;  1PWQ A;  1SRP A;  1JH1 A;  4WKI A;  1MNC A;  2X3C A;  1ZXC A;  3O64 A;  1XUC A;  1IAB A;  4FXQ A;  1YQY A;  3DL1 A;  966C A;  3LIL A;  2ERO A;  3KEJ A;  1WNI A;  5I3M A;  3Q2H A;  3F18 A;  1Z3J A;  3KWV C;  3USN A;  1A86 A;  2W0D A;  2OY2 A;  1JAQ A;  1BKC I;  1OS2 A;  1KUG A;  4ZR5 A;  1I73 A;  1MMQ A;  3EDI A;  3AIG A;  2USN A;  4L63 A;  1C7K A;  1R55 A;  1XFW A;  1QIB A;  1G4K A;  1B3D A;  3OHO A;  1PWV A;  1UMS A;  2W12 A;  2DDF A;  4I03 A;  3KME A;  4G0D A;  3LUM A;  3LJT A;  2PJT A;  5D1S A;  2CLT A;  1L6J A;  3TT4 A; 
#chains in the Genus database with same CATH topology
 1EUB A;  456C A;  5D7W A;  1BM6 A;  2L0R A;  3UVC A;  2FV5 A;  3DPF A;  3G42 A;  3B2Z A;  1D5J A;  1RM8 A;  2MZE A;  4XM8 A;  3L0T A;  4L7A A;  2OW1 A;  3DSL A;  4H1Q A;  4JQG A;  3B8Z A;  1G9K A;  4FVL A;  4QKZ A;  4FXY P;  2OW9 A;  3O2X A;  4GF1 A;  2V4B A;  2J83 A;  4AYK A;  1KUI A;  2OY4 A;  2MZH A;  1MMR A;  1XAX A;  5I12 A;  3F1A A;  1SU3 A;  3LK8 A;  2XS3 A;  1BIW A;  4PKW A;  1R54 A;  3LQB A;  1GKC A;  3HBV P;  4AUO A;  1D8F A;  4AXQ A;  1CQR A;  1Q3A A;  5CZM A;  3K7N A;  3GBO A;  1QIC A;  3EDZ A;  1ZP5 A;  1GE7 A;  3LMC A;  4WKE A;  2FV9 A;  4H49 A;  2JNP A;  5I4O A;  1JKY A;  3HDA P;  1OM6 A;  3K7L A;  2W14 A;  2POJ A;  3LJZ A;  3MA2 A;  1CGL A;  4I35 A;  1QUA A;  3LE9 A;  4IN9 A;  2JIH A;  1A85 A;  1ROS A;  2D1N A;  1AKL A;  5I43 A;  2XS4 A;  3EHY A;  3KEC A;  1C3I A;  2AYK A;  2Z2D A;  1IAA A;  1R1H A;  1OS9 A;  5LAB A;  1XFY A;  2Y6D A;  3B92 A;  4A3W A;  2N8R A;  3ELM A;  1BZS A;  1JJ9 A;  1HY7 A;  1SLN A;  4H82 A;  4DD8 A;  3ZXH A;  1G05 A;  3Q2G A;  1PWU A;  2JT5 A;  2OVX A;  2X7M A;  1USN A;  2OXU A;  5D2B A;  4L19 A;  3ZUK A;  1SMP A;  3RTS A;  3SHI A;  1Y0V A;  4DF9 A;  1OM8 A;  1FLS A;  2O3E A;  3U1R A;  2TCL A;  1TVI A;  2WO9 A;  4DV8 A;  3LGP A;  4ON1 A;  4GR3 A;  1ATL A;  5L7F A;  1XFV A;  1FM1 A;  3LQ0 A;  3VI1 A;  3HYG A;  2OW2 A;  4JP4 A;  3DNG A;  4GWM A;  1I76 A;  1UEA A;  3HBU P;  3DTI A;  3BA0 A;  1DTH A;  4WF6 A;  3E8R A;  4JPA A;  1XFX A;  2X3A A;  4A7B A;  1ZTQ A;  2AIG P;  3N2V A;  2K2G A;  5I0L A;  2OVZ A;  1JK3 A;  1HFC A;  2O36 A;  2OZR A;  1CAQ A;  1G49 A;  1GO7 P;  3LIR A;  3TSK A;  1EAK A;  4GQL A;  3NX7 A;  1BKC E;  2MLS A;  3WV2 A;  1GXD A;  3LUN A;  3EWJ A;  4EFS A;  3I7I A;  1GE6 A;  2DDY A;  3LEA A;  3WV1 A;  3HY9 A;  830C A;  1HFS A;  3N2U A;  1KUK A;  4GWN A;  1D7X A;  3F19 A;  2ERP A;  1GKD A;  3V96 B;  1HV5 A;  3AYU A;  3F15 A;  4PKV A;  4J4M A;  1QJI A;  2KRJ A;  1O0Q A;  1QIA A;  4GR0 A;  4ILW D;  1R1I A;  2A8H A;  1KAP P;  1BKC A;  1IAD A;  3HDB A;  1AYK A;  1IAE A;  3KRY A;  3TS4 A;  2E2D A;  3CKI A;  2OXW A;  1K7I A;  2WO8 A;  1RMZ A;  3LKA A;  2J0T A;  2SRT A;  1XUR A;  3KMC A;  2JT6 A;  2OW0 A;  1Y93 A;  1EB6 A;  1FBL A;  2K9C A;  1PWP A;  1JAP A;  4XM7 A;  1ND1 A;  3ZVS A;  2DW2 A;  5CUH A;  5BOY A;  3DTK A;  1SAT A;  4PKQ A;  3OHL A;  4JIJ A;  1XFU A;  2QPJ A;  1GE5 A;  4H84 A;  2W13 A;  4H2E A;  4H30 A;  1YP1 A;  3TVC A;  5BOT A;  1D8M A;  2W15 A;  2MZI A;  4WK7 A;  1C8T A;  4Q1L A;  4CTH A;  3LIK A;  1JAN A;  1CXV A;  4R3V A;  1BSW A;  2HU6 A;  4XBH A;  2ERQ A;  2JSD A;  1CGF A;  1O0T A;  1XM5 A;  3DTE A;  3F16 A;  3EDG A;  2E3X A;  5BPA A;  2MLR A;  1I1I P;  2D1O A;  1OO9 A;  2OI0 A;  1AF0 A;  1CK7 A;  3VTG A;  4G9L A;  3I7G A;  3KEK A;  3P24 A;  1G12 A;  3LJG A;  1IAG A;  5D1U A;  2WOA A;  1K7Q A;  1UTZ A;  1BQO A;  3L0V A;  4XCT A;  2CKI A;  1YOU A;  1JIW P;  3WV3 A;  1K7G A;  4H3X A;  5H8X A;  1GO8 P;  4WZV A;  1R1J A;  2Y6C A;  1BQQ M;  1JAO A;  1QJJ A;  4PKT A;  5B5P A;  1JIZ A;  4PKU A;  3P1V A;  5L79 A;  5D3C A;  4GR8 A;  1IAC A;  1KUH A;  3G5C A;  4JA1 A;  3EHX A;  1UMT A;  2DW1 A;  2DW0 A;  3F17 A;  3KHI A;  1UTT A;  1H71 P;  1YCM A;  3DWB A;  4PKR A;  1KUF A;  2YB9 A;  1MMB A;  1AST A;  1J7N A;  3HY7 A;  5CXA A;  1HTD A;  4IJO A;  4PKS A;  1CIZ A;  1BUV M;  3RTT A;  1MMP A;  4L6T A;  4IUW A;  1ZXV A;  3EDH A;  1B8Y A;  2X3B A;  1ZVX A;  2I47 A;  1XUD A;  1Y8J A;  2YIG A;  2RJP A;  5I2Z A;  4GUY A;  1SLM A;  1CGE A;  1OMJ A;  2RJQ A;  1HOV A;  2OXZ A;  4HMA A;  1KBC A;  4FU4 A;  3AYK A;  3HB2 P;  1OM7 A;  4XM6 A;  3DPE A;  5D1T A;  4DPE A;  1XFZ A;  4AIG A;  5B5O A;  5JMY A;  1BUD A;  4H76 A;  1ZS0 A;  4HX3 A;  1DMT A;  1PWW A;  1S4B P;  1PWQ A;  1SRP A;  2YUF A;  1JH1 A;  4WKI A;  1MNC A;  2X3C A;  1ZXC A;  3O64 A;  1XUC A;  1IAB A;  4FXQ A;  1YQY A;  3DL1 A;  966C A;  3LIL A;  2ERO A;  3KEJ A;  1WNI A;  5I3M A;  3Q2H A;  3F18 A;  1Z3J A;  3KWV C;  3USN A;  1A86 A;  2W0D A;  2OY2 A;  1JAQ A;  1BKC I;  1OS2 A;  1KUG A;  4ZR5 A;  1I73 A;  1MMQ A;  3EDI A;  3AIG A;  2USN A;  4L63 A;  1C7K A;  1R55 A;  1XFW A;  1QIB A;  1G4K A;  1B3D A;  3OHO A;  1PWV A;  1UMS A;  2W12 A;  2DDF A;  4I03 A;  3KME A;  4G0D A;  3LUM A;  1OZ9 A;  3LJT A;  2PJT A;  5D1S A;  2CLT A;  1L6J A;  3TT4 A; 
#chains in the Genus database with same CATH homology
 1EUB A;  456C A;  5D7W A;  1BM6 A;  2L0R A;  3UVC A;  2FV5 A;  3DPF A;  3G42 A;  3B2Z A;  1D5J A;  1RM8 A;  2MZE A;  4XM8 A;  3L0T A;  4L7A A;  2OW1 A;  3DSL A;  4H1Q A;  4JQG A;  3B8Z A;  1G9K A;  4FVL A;  4QKZ A;  4FXY P;  2OW9 A;  3O2X A;  4GF1 A;  2V4B A;  2J83 A;  4AYK A;  1KUI A;  2OY4 A;  2MZH A;  1MMR A;  5I12 A;  3F1A A;  1SU3 A;  3LK8 A;  2XS3 A;  1BIW A;  4PKW A;  1R54 A;  3LQB A;  1GKC A;  3HBV P;  4AUO A;  1D8F A;  4AXQ A;  1CQR A;  1Q3A A;  5CZM A;  3K7N A;  3GBO A;  1QIC A;  3EDZ A;  1ZP5 A;  1GE7 A;  3LMC A;  4WKE A;  2FV9 A;  4H49 A;  2JNP A;  5I4O A;  1JKY A;  3HDA P;  1OM6 A;  3K7L A;  2W14 A;  2POJ A;  3LJZ A;  3MA2 A;  1CGL A;  4I35 A;  1QUA A;  3LE9 A;  4IN9 A;  2JIH A;  1A85 A;  1ROS A;  2D1N A;  1AKL A;  5I43 A;  2XS4 A;  3EHY A;  3KEC A;  1C3I A;  2AYK A;  2Z2D A;  1IAA A;  1R1H A;  1OS9 A;  5LAB A;  1XFY A;  2Y6D A;  3B92 A;  4A3W A;  2N8R A;  3ELM A;  1BZS A;  1JJ9 A;  1HY7 A;  1SLN A;  4H82 A;  4DD8 A;  3ZXH A;  1G05 A;  3Q2G A;  1PWU A;  2JT5 A;  2OVX A;  2X7M A;  1USN A;  2OXU A;  5D2B A;  4L19 A;  3ZUK A;  1SMP A;  3RTS A;  3SHI A;  1Y0V A;  4DF9 A;  1OM8 A;  1FLS A;  2O3E A;  3U1R A;  2TCL A;  2WO9 A;  4DV8 A;  3LGP A;  4ON1 A;  4GR3 A;  1ATL A;  5L7F A;  1XFV A;  1FM1 A;  3LQ0 A;  3VI1 A;  3HYG A;  2OW2 A;  4JP4 A;  3DNG A;  4GWM A;  1I76 A;  1UEA A;  3HBU P;  3DTI A;  3BA0 A;  1DTH A;  4WF6 A;  3E8R A;  4JPA A;  1XFX A;  2X3A A;  4A7B A;  1ZTQ A;  2AIG P;  3N2V A;  2K2G A;  5I0L A;  2OVZ A;  1JK3 A;  1HFC A;  2O36 A;  2OZR A;  1CAQ A;  1G49 A;  1GO7 P;  3LIR A;  3TSK A;  1EAK A;  4GQL A;  3NX7 A;  1BKC E;  2MLS A;  3WV2 A;  1GXD A;  3LUN A;  3EWJ A;  4EFS A;  3I7I A;  1GE6 A;  2DDY A;  3LEA A;  3WV1 A;  3HY9 A;  830C A;  1HFS A;  3N2U A;  1KUK A;  4GWN A;  1D7X A;  3F19 A;  2ERP A;  1GKD A;  3V96 B;  1HV5 A;  3AYU A;  3F15 A;  4PKV A;  4J4M A;  1QJI A;  2KRJ A;  1O0Q A;  1QIA A;  4GR0 A;  4ILW D;  1R1I A;  2A8H A;  1KAP P;  1BKC A;  1IAD A;  3HDB A;  1AYK A;  1IAE A;  3KRY A;  3TS4 A;  2E2D A;  3CKI A;  2OXW A;  1K7I A;  2WO8 A;  1RMZ A;  3LKA A;  2J0T A;  2SRT A;  1XUR A;  3KMC A;  2JT6 A;  2OW0 A;  1Y93 A;  1EB6 A;  1FBL A;  2K9C A;  1PWP A;  1JAP A;  4XM7 A;  1ND1 A;  3ZVS A;  2DW2 A;  5CUH A;  5BOY A;  3DTK A;  1SAT A;  4PKQ A;  3OHL A;  4JIJ A;  1XFU A;  2QPJ A;  1GE5 A;  4H84 A;  2W13 A;  4H2E A;  4H30 A;  1YP1 A;  3TVC A;  5BOT A;  1D8M A;  2W15 A;  2MZI A;  4WK7 A;  1C8T A;  4Q1L A;  4CTH A;  3LIK A;  1JAN A;  1CXV A;  4R3V A;  1BSW A;  2HU6 A;  4XBH A;  2ERQ A;  2JSD A;  1CGF A;  1O0T A;  3DTE A;  3F16 A;  3EDG A;  2E3X A;  5BPA A;  2MLR A;  1I1I P;  2D1O A;  1OO9 A;  2OI0 A;  1AF0 A;  1CK7 A;  3VTG A;  4G9L A;  3I7G A;  3KEK A;  3P24 A;  1G12 A;  3LJG A;  1IAG A;  5D1U A;  2WOA A;  1K7Q A;  1UTZ A;  1BQO A;  3L0V A;  4XCT A;  2CKI A;  1YOU A;  1JIW P;  3WV3 A;  1K7G A;  4H3X A;  5H8X A;  1GO8 P;  4WZV A;  1R1J A;  2Y6C A;  1BQQ M;  1JAO A;  1QJJ A;  4PKT A;  5B5P A;  1JIZ A;  4PKU A;  3P1V A;  5L79 A;  5D3C A;  4GR8 A;  1IAC A;  1KUH A;  3G5C A;  4JA1 A;  3EHX A;  1UMT A;  2DW1 A;  2DW0 A;  3F17 A;  3KHI A;  1UTT A;  1H71 P;  1YCM A;  3DWB A;  4PKR A;  1KUF A;  2YB9 A;  1MMB A;  1AST A;  1J7N A;  3HY7 A;  5CXA A;  1HTD A;  4IJO A;  4PKS A;  1CIZ A;  1BUV M;  3RTT A;  1MMP A;  4L6T A;  4IUW A;  1ZXV A;  3EDH A;  1B8Y A;  2X3B A;  1ZVX A;  2I47 A;  1XUD A;  1Y8J A;  2YIG A;  2RJP A;  5I2Z A;  4GUY A;  1SLM A;  1CGE A;  1OMJ A;  2RJQ A;  1HOV A;  2OXZ A;  4HMA A;  1KBC A;  4FU4 A;  3AYK A;  3HB2 P;  1OM7 A;  4XM6 A;  3DPE A;  5D1T A;  4DPE A;  1XFZ A;  4AIG A;  5B5O A;  5JMY A;  1BUD A;  4H76 A;  1ZS0 A;  4HX3 A;  1DMT A;  1PWW A;  1S4B P;  1PWQ A;  1SRP A;  2YUF A;  1JH1 A;  4WKI A;  1MNC A;  2X3C A;  1ZXC A;  3O64 A;  1XUC A;  1IAB A;  4FXQ A;  1YQY A;  3DL1 A;  966C A;  3LIL A;  2ERO A;  3KEJ A;  1WNI A;  5I3M A;  3Q2H A;  3F18 A;  1Z3J A;  3KWV C;  3USN A;  1A86 A;  2W0D A;  2OY2 A;  1JAQ A;  1BKC I;  1OS2 A;  1KUG A;  4ZR5 A;  1I73 A;  1MMQ A;  3EDI A;  3AIG A;  2USN A;  4L63 A;  1C7K A;  1R55 A;  1XFW A;  1QIB A;  1G4K A;  1B3D A;  3OHO A;  1PWV A;  1UMS A;  2W12 A;  2DDF A;  4I03 A;  3KME A;  4G0D A;  3LUM A;  3LJT A;  2PJT A;  5D1S A;  2CLT A;  1L6J A;  3TT4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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