1QUAA

Crystal structure of acutolysin-c, a hemorrhagic toxin from the snake venom of agkistrodon acutus, at 2.2 a resolution
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
197
structure length
197
Chain Sequence
PAPQTSIELFLIVDHSMYAKYNSNSSKITTTLKARVNIMNAIYSSLNLVITLSGIEMWSAADLITVQSSSRNTLKLFASWRETDLLKRTSNDNAQLLTATNFNGNTVGLAYLKTMCNSKYSVGLIQDHSAIPLLMAVTMAHELGHNLGMNHDGAGCSCATCIMAPVLSSGPAKSFSDCSKHDYQSFLTIHKPQCLLN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of acutolysin-C, a haemorrhagic toxin from the venom of Agkistrodon acutus, providing further evidence for the mechanism of the pH-dependent proteolytic reaction of zinc metalloproteinases.
pubmed doi rcsb
molecule tags Toxin
molecule keywords ACUTOLYSIN-C
total genus 68
structure length 197
sequence length 197
ec nomenclature
pdb deposition date 1999-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01421 Reprolysin Reprolysin (M12B) family zinc metalloprotease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1quaA00
3AIGA 1A86A 2CKIA 1RMZA 4XCTA 1QJIA 2OW2A 1GE5A 1O0QA 5D3CA 2WO8A 1BQOA 1CGLA 3EDHA 3LGPA 1XUDA 3DWBA 1YQYA 1SLNA 1Y8JA 4JQGA 3LUMA 1KUHA 3O64A 4GWNA 3KMCA 4H76A 2E3XA 3F18A 3KECA 1EUBA 1ZS0A 1C8TA 1R1HA 2AIGP 4GUYA 4PKVA 4EFSA 3LIRA 4GQLA 2JT5A 2OW9A 3GBOA 3AYKA 2EROA 2DW0A 3ZVSA 3OHOA 1D8MA 4WKIA 1Y0VA 3LQBA 2YB9A 3VTGA 3F19A 1R1IA 3MA2A 1PWWA 2X3CA 3EHYA 1AF0A 1BSWA 2JIHA 1ZVXA 3L0VA 1QUAA 3DNGA 3EDZA 4AUOA 1C7KA 3DSLA 2RJPA 3ZXHA 4WKEA 3HY9A 1QIBA 4IUWA 4H49A 3KEKA 2OXWA 3TVCA 1ATLA 5B5PA 1WNIA 3B92A 1L6JA 2OY2A 2AYKA 1HFCA 1YCMA 3DL1A 1UTTA 2X3BA 2POJA 3Q2HA 3Q2GA 3RTSA 3I7GA 5H8XA 3USNA 966CA 1IADA 3K7NA 1YP1A 4PKRA 2D1NA 5D1SA 1QIAA 2MLRA 4XM8A 1EAKA 3V96B 1GXDA 1BUDA 1JJ9A 2K2GA 5CUHA 1HV5A 1C3IA 1GKCA 1PWPA 2OVZA 1BKCI 1SMPA 4QKZA 1IAEA 1G12A 4XBHA 4I03A 4DV8A 1CIZA 1AYKA 1XFWA 830CA 4AYKA 3LJZA 1RM8A 1OM6A 2JNPA 1JIWP 1IACA 1O0TA 1BQQM 4PKSA 1AKLA 2ERPA 1ZXVA 4G9LA 3E8RA 1OO9A 3B8ZA 2DW1A 5CZMA 1UMSA 1Q3AA 2FV5A 4PKQA 2DDFA 2MZIA 5I12A 3SHIA 1B8YA 2HU6A 1JKYA 1GO7P 3I7IA 1Z3JA 4I35A 1JIZA 1G05A 2FV9A 1R54A 1DMTA 3HDAP 1XURA 3OHLA 4HMAA 1HFSA 2I47A 4L63A 4CTHA 2TCLA 4R3VA 1SLMA 4JP4A 3TS4A 4JPAA 2JSDA 4PKTA 4FXQA 4WZVA 2DW2A 1OS9A 2ERQA 1DTHA 2N8RA 1GE7A 4ZR5A 3AYUA 3UVCA 4ILWD 5LABA 4Q1LA 2Z2DA 1YOUA 3ELMA 1USNA 3CKIA 1HY7A 5BOYA 2D1OA 2USNA 1CAQA 3F15A 1XFXA 3HYGA 1S4BP 5D7WA 1SU3A 1PWVA 1G4KA 2OW1A 1CK7A 2OZRA 1MMRA 5I43A 1SATA 4L6TA 3TT4A 2XS3A 1JH1A 2MLSA 1ZTQA 2W14A 1HOVA 2X7MA 3DPEA 1ZP5A 4GWMA 3LKAA 3HBVP 2W0DA 4WF6A 2PJTA 3LK8A 4GR0A 1H71P 5CXAA 2Y6CA 2K9CA 5BOTA 1GKDA 4AIGA 4L19A 2MZHA 3P24A 2DDYA 4H84A 1GE6A 1UEAA 4IJOA 456CA 2OXZA 4DF9A 1IAGA 5JMYA 1XFVA 3ZUKA 2JT6A 1KBCA 1OS2A 1ASTA 1JAQA 1ZXCA 1IABA 1I76A 2XS4A 3LEAA 4JA1A 4A7BA 3WV3A 2RJQA 3NX7A 1PWUA 1FBLA 1GO8P 1B3DA 3L0TA 1EB6A 4G0DA 4IN9A 1KUGA 3LQ0A 1JAOA 4FVLA 2W13A 4A3WA 1ROSA 3EDIA 1BUVM 1HTDA 5I4OA 2MZEA 2WO9A 1CGFA 1G9KA 3G5CA 1PWQA 1K7IA 1FM1A 4H1QA 5D1TA 1MMQA 1XFUA 4GF1A 3HY7A 3F1AA 1CGEA 1D8FA 1J7NA 1CXVA 4H82A 5D2BA 3WV1A 2SRTA 3O2XA 5I3MA 1OMJA 3KMEA 1XFYA 1K7GA 1MMPA 1JANA 2O3EA 1JK3A 1BZSA 4H2EA 2OI0A 1BKCE 1IAAA 1G49A 1MMBA 1UMTA 2OW0A 3N2VA 1KAPP 3TSKA 1XUCA 3G42A 2J83A 1Y93A 1MNCA 2Y6DA 2X3AA 4GR3A 4XM7A 2W15A 3BA0A 3LE9A 4DPEA 2WOAA 5B5OA 1QICA 3VI1A 1OM7A 1SRPA 2A8HA 4PKUA 2OVXA 1A85A 4HX3A 1KUFA 4J4MA 4GR8A 3KWVC 3LJGA 3EDGA 3K7LA 3B2ZA 2O36A 3P1VA 3KRYA 1KUIA 2OXUA 2L0RA 1UTZA 3EHXA 5L7FA 3LMCA 1D5JA 2E2DA 1BKCA 4XM6A 1KUKA 3HB2P 4FU4A 1BIWA 4AXQA 4WK7A 2OY4A 3F17A 2W12A 3LIKA 2QPJA 1K7QA 3RTTA 5I2ZA 1OM8A 4H30A 3EWJA 1R1JA 3HDBA 3U1RA 4JIJA 1FLSA 3LUNA 5BPAA 2YIGA 3KHIA 3LJTA 1XFZA 1I73A 3N2UA 1BM6A 3LILA 5L79A 4DD8A 3DPFA 1D7XA 4ON1A 2KRJA 2J0TA 3WV2A 4H3XA 1CQRA 3HBUP 1ND1A 2CLTA 3F16A 1JAPA 5I0LA 1QJJA 1I1IP 4FXYP 4PKWA 1R55A 5D1UA 2V4BA 3KEJA
chains in the Genus database with same CATH superfamily
3AIGA 1A86A 2CKIA 1RMZA 4XCTA 1QJIA 2OW2A 1GE5A 1O0QA 5D3CA 2WO8A 1BQOA 1CGLA 3EDHA 3LGPA 1XUDA 3DWBA 1YQYA 1SLNA 1Y8JA 4JQGA 3LUMA 1KUHA 3O64A 4GWNA 3KMCA 4H76A 2E3XA 3F18A 3KECA 1EUBA 1ZS0A 1C8TA 1R1HA 2AIGP 4GUYA 4PKVA 4EFSA 3LIRA 4GQLA 2JT5A 2OW9A 3GBOA 3AYKA 2EROA 2DW0A 3ZVSA 3OHOA 1D8MA 4WKIA 1Y0VA 3LQBA 2YB9A 3VTGA 3F19A 1R1IA 3MA2A 1PWWA 2X3CA 3EHYA 1AF0A 1BSWA 2JIHA 1ZVXA 3L0VA 1QUAA 3DNGA 3EDZA 4AUOA 1C7KA 3DSLA 2RJPA 3ZXHA 4WKEA 3HY9A 1QIBA 4IUWA 4H49A 3KEKA 2OXWA 3TVCA 1ATLA 5B5PA 1WNIA 3B92A 1L6JA 2OY2A 2AYKA 1HFCA 1YCMA 3DL1A 1UTTA 2X3BA 2POJA 3Q2HA 3Q2GA 3RTSA 3I7GA 5H8XA 3USNA 966CA 1IADA 3K7NA 1YP1A 4PKRA 2D1NA 5D1SA 1QIAA 2MLRA 4XM8A 1EAKA 3V96B 3DTEA 1GXDA 1BUDA 1JJ9A 2K2GA 5CUHA 1HV5A 1C3IA 1GKCA 1PWPA 2OVZA 1BKCI 1OZ9A 1SMPA 4QKZA 1IAEA 1G12A 4XBHA 4I03A 4DV8A 1CIZA 1AYKA 4L7AA 1XFWA 830CA 1TVIA 4AYKA 3LJZA 1RM8A 1OM6A 2JNPA 1JIWP 1IACA 1O0TA 1BQQM 4PKSA 1AKLA 2ERPA 1ZXVA 4G9LA 3E8RA 1OO9A 1XM5A 3B8ZA 2DW1A 5CZMA 1UMSA 1Q3AA 2FV5A 4PKQA 2DDFA 2MZIA 5I12A 3SHIA 1B8YA 2HU6A 1JKYA 1GO7P 3I7IA 1Z3JA 4I35A 1JIZA 1G05A 2FV9A 1R54A 1DMTA 3HDAP 1XURA 3OHLA 4HMAA 1HFSA 2I47A 4L63A 4CTHA 2TCLA 4R3VA 1SLMA 4JP4A 3TS4A 4JPAA 2JSDA 4PKTA 4FXQA 4WZVA 2DW2A 1OS9A 2ERQA 1DTHA 2N8RA 1GE7A 4ZR5A 3AYUA 3UVCA 4ILWD 5LABA 4Q1LA 2Z2DA 1YOUA 3ELMA 1USNA 3CKIA 1HY7A 5BOYA 2D1OA 2USNA 1CAQA 3F15A 1XFXA 3HYGA 1S4BP 5D7WA 1SU3A 1PWVA 1G4KA 2OW1A 1CK7A 2OZRA 1MMRA 5I43A 1SATA 4L6TA 3TT4A 2XS3A 1JH1A 2MLSA 3DTIA 1ZTQA 2W14A 1HOVA 2X7MA 3DPEA 1ZP5A 4GWMA 3LKAA 3HBVP 2W0DA 4WF6A 2PJTA 3LK8A 4GR0A 1H71P 5CXAA 2Y6CA 2K9CA 5BOTA 1GKDA 4AIGA 4L19A 2MZHA 3P24A 2DDYA 4H84A 1GE6A 1UEAA 4IJOA 456CA 2OXZA 4DF9A 1IAGA 5JMYA 1XFVA 3ZUKA 2JT6A 1KBCA 1OS2A 1ASTA 1JAQA 1ZXCA 1IABA 1I76A 2XS4A 3LEAA 4JA1A 4A7BA 3WV3A 2RJQA 3NX7A 1PWUA 3DTKA 1FBLA 1GO8P 1B3DA 3L0TA 1EB6A 4G0DA 4IN9A 1KUGA 3LQ0A 1JAOA 4FVLA 2W13A 4A3WA 1ROSA 3EDIA 1BUVM 1HTDA 5I4OA 2MZEA 2WO9A 1CGFA 1G9KA 3G5CA 1PWQA 1K7IA 1FM1A 4H1QA 5D1TA 1MMQA 1XFUA 4GF1A 3HY7A 3F1AA 1CGEA 1D8FA 1J7NA 1CXVA 4H82A 5D2BA 3WV1A 2SRTA 3O2XA 5I3MA 1OMJA 3KMEA 1XFYA 1K7GA 1MMPA 1JANA 2O3EA 1JK3A 1BZSA 4H2EA 2OI0A 1BKCE 1IAAA 1G49A 1MMBA 1UMTA 2OW0A 3N2VA 1KAPP 3TSKA 1XUCA 3G42A 2J83A 1Y93A 1MNCA 2Y6DA 2X3AA 4GR3A 4XM7A 2W15A 3BA0A 3LE9A 4DPEA 2WOAA 5B5OA 1QICA 3VI1A 1OM7A 1SRPA 2A8HA 4PKUA 2OVXA 1A85A 4HX3A 1KUFA 4J4MA 4GR8A 3KWVC 3LJGA 3EDGA 3K7LA 3B2ZA 2O36A 3P1VA 3KRYA 1XAXA 1KUIA 2OXUA 2L0RA 1UTZA 3EHXA 5L7FA 3LMCA 1D5JA 2E2DA 1BKCA 4XM6A 1KUKA 3HB2P 4FU4A 1BIWA 4AXQA 4WK7A 2OY4A 3F17A 2W12A 3LIKA 2QPJA 1K7QA 3RTTA 5I2ZA 1OM8A 4H30A 3EWJA 3HDBA 1R1JA 2YUFA 3U1RA 4JIJA 1FLSA 3LUNA 5BPAA 2YIGA 3KHIA 3LJTA 1XFZA 1I73A 3N2UA 1BM6A 3LILA 5L79A 4DD8A 3DPFA 1D7XA 4ON1A 2KRJA 2J0TA 3WV2A 4H3XA 1CQRA 3HBUP 1ND1A 2CLTA 3F16A 1JAPA 5I0LA 1QJJA 1I1IP 4FXYP 4PKWA 1R55A 5D1UA 2V4BA 3KEJA
chains in the Genus database with same CATH topology
3AIGA 1A86A 2CKIA 1RMZA 4XCTA 1QJIA 2OW2A 1GE5A 1O0QA 5D3CA 2WO8A 1BQOA 1CGLA 3EDHA 3LGPA 1XUDA 3DWBA 1YQYA 1SLNA 1Y8JA 4JQGA 3LUMA 1KUHA 3O64A 4GWNA 3KMCA 4H76A 2E3XA 3F18A 3KECA 1EUBA 1ZS0A 1C8TA 1R1HA 2AIGP 4GUYA 4PKVA 4EFSA 3LIRA 4GQLA 2JT5A 2OW9A 3GBOA 3AYKA 2EROA 2DW0A 3ZVSA 3OHOA 1D8MA 4WKIA 1Y0VA 3LQBA 2YB9A 3VTGA 3F19A 1R1IA 3MA2A 1PWWA 2X3CA 3EHYA 1AF0A 1BSWA 2JIHA 1ZVXA 3L0VA 1QUAA 3DNGA 3EDZA 4AUOA 1C7KA 3DSLA 2RJPA 3ZXHA 4WKEA 3HY9A 1QIBA 4IUWA 4H49A 3KEKA 2OXWA 3TVCA 1ATLA 5B5PA 1WNIA 3B92A 1L6JA 2OY2A 2AYKA 1HFCA 1YCMA 3DL1A 1UTTA 2X3BA 2POJA 3Q2HA 3Q2GA 3RTSA 3I7GA 5H8XA 3USNA 966CA 1IADA 3K7NA 1YP1A 4PKRA 2D1NA 5D1SA 1QIAA 2MLRA 4XM8A 1EAKA 3V96B 3DTEA 1GXDA 1BUDA 1JJ9A 2K2GA 5CUHA 1HV5A 1C3IA 1GKCA 1PWPA 2OVZA 1BKCI 1SMPA 4QKZA 1IAEA 1G12A 4XBHA 4I03A 4DV8A 1CIZA 1AYKA 4L7AA 1XFWA 830CA 4AYKA 3LJZA 1RM8A 1OM6A 2JNPA 1JIWP 1IACA 1O0TA 1BQQM 4PKSA 1AKLA 2ERPA 1ZXVA 4G9LA 3E8RA 1OO9A 3B8ZA 2DW1A 5CZMA 1UMSA 1Q3AA 2FV5A 4PKQA 2DDFA 2MZIA 5I12A 3SHIA 1B8YA 2HU6A 1JKYA 1GO7P 3I7IA 1Z3JA 4I35A 1JIZA 1G05A 2FV9A 1R54A 1DMTA 3HDAP 1XURA 3OHLA 4HMAA 1HFSA 2I47A 4L63A 4CTHA 2TCLA 4R3VA 1SLMA 4JP4A 3TS4A 4JPAA 2JSDA 4PKTA 4FXQA 4WZVA 2DW2A 1OS9A 2ERQA 1DTHA 2N8RA 1GE7A 4ZR5A 3AYUA 3UVCA 4ILWD 5LABA 4Q1LA 2Z2DA 1YOUA 3ELMA 1USNA 3CKIA 1HY7A 5BOYA 2D1OA 2USNA 1CAQA 3F15A 1XFXA 3HYGA 1S4BP 5D7WA 1SU3A 1PWVA 1G4KA 2OW1A 1CK7A 2OZRA 1MMRA 5I43A 1SATA 4L6TA 3TT4A 2XS3A 1JH1A 2MLSA 3DTIA 1ZTQA 2W14A 1HOVA 2X7MA 3DPEA 1ZP5A 4GWMA 3LKAA 3HBVP 2W0DA 4WF6A 2PJTA 3LK8A 4GR0A 1H71P 5CXAA 2Y6CA 2K9CA 5BOTA 1GKDA 4AIGA 4L19A 2MZHA 3P24A 2DDYA 4H84A 1GE6A 1UEAA 4IJOA 456CA 2OXZA 4DF9A 1IAGA 5JMYA 1XFVA 3ZUKA 2JT6A 1KBCA 1OS2A 1ASTA 1JAQA 1ZXCA 1IABA 1I76A 2XS4A 3LEAA 4JA1A 4A7BA 3WV3A 2RJQA 3NX7A 1PWUA 3DTKA 1FBLA 1GO8P 1B3DA 3L0TA 1EB6A 4G0DA 4IN9A 1KUGA 3LQ0A 1JAOA 4FVLA 2W13A 4A3WA 1ROSA 3EDIA 1BUVM 1HTDA 5I4OA 2MZEA 2WO9A 1CGFA 1G9KA 3G5CA 1PWQA 1K7IA 1FM1A 4H1QA 5D1TA 1MMQA 1XFUA 4GF1A 3HY7A 3F1AA 1CGEA 1D8FA 1J7NA 1CXVA 4H82A 5D2BA 3WV1A 2SRTA 3O2XA 5I3MA 1OMJA 3KMEA 1XFYA 1K7GA 1MMPA 1JANA 2O3EA 1JK3A 1BZSA 4H2EA 2OI0A 1BKCE 1IAAA 1G49A 1MMBA 1UMTA 2OW0A 3N2VA 1KAPP 3TSKA 1XUCA 3G42A 2J83A 1Y93A 1MNCA 2Y6DA 2X3AA 4GR3A 4XM7A 2W15A 3BA0A 3LE9A 4DPEA 2WOAA 5B5OA 1QICA 3VI1A 1OM7A 1SRPA 2A8HA 4PKUA 2OVXA 1A85A 4HX3A 1KUFA 4J4MA 4GR8A 3KWVC 3LJGA 3EDGA 3K7LA 3B2ZA 2O36A 3P1VA 3KRYA 1KUIA 2OXUA 2L0RA 1UTZA 3EHXA 5L7FA 3LMCA 1D5JA 2E2DA 1BKCA 4XM6A 1KUKA 3HB2P 4FU4A 1BIWA 4AXQA 4WK7A 2OY4A 3F17A 2W12A 3LIKA 2QPJA 1K7QA 3RTTA 5I2ZA 1OM8A 4H30A 3EWJA 3HDBA 1R1JA 2YUFA 3U1RA 4JIJA 1FLSA 3LUNA 5BPAA 2YIGA 3KHIA 3LJTA 1XFZA 1I73A 3N2UA 1BM6A 3LILA 5L79A 4DD8A 3DPFA 1D7XA 4ON1A 2KRJA 2J0TA 3WV2A 4H3XA 1CQRA 3HBUP 1ND1A 2CLTA 3F16A 1JAPA 5I0LA 1QJJA 1I1IP 4FXYP 4PKWA 1R55A 5D1UA 2V4BA 3KEJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AIG A;  1A86 A;  2CKI A;  1RMZ A;  4XCT A;  1QJI A;  2OW2 A;  1GE5 A;  1O0Q A;  5D3C A;  2WO8 A;  1BQO A;  1CGL A;  3EDH A;  3LGP A;  1XUD A;  3DWB A;  1YQY A;  1SLN A;  1Y8J A;  4JQG A;  3LUM A;  1KUH A;  3O64 A;  4GWN A;  3KMC A;  4H76 A;  2E3X A;  3F18 A;  3KEC A;  1EUB A;  1ZS0 A;  1C8T A;  1R1H A;  2AIG P;  4GUY A;  4PKV A;  4EFS A;  3LIR A;  4GQL A;  2JT5 A;  2OW9 A;  3GBO A;  3AYK A;  2ERO A;  2DW0 A;  3ZVS A;  3OHO A;  1D8M A;  4WKI A;  1Y0V A;  3LQB A;  2YB9 A;  3VTG A;  3F19 A;  1R1I A;  3MA2 A;  1PWW A;  2X3C A;  3EHY A;  1AF0 A;  1BSW A;  2JIH A;  1ZVX A;  3L0V A;  1QUA A;  3DNG A;  3EDZ A;  4AUO A;  1C7K A;  3DSL A;  2RJP A;  3ZXH A;  4WKE A;  3HY9 A;  1QIB A;  4IUW A;  4H49 A;  3KEK A;  2OXW A;  3TVC A;  1ATL A;  5B5P A;  1WNI A;  3B92 A;  1L6J A;  2OY2 A;  2AYK A;  1HFC A;  1YCM A;  3DL1 A;  1UTT A;  2X3B A;  2POJ A;  3Q2H A;  3Q2G A;  3RTS A;  3I7G A;  5H8X A;  3USN A;  966C A;  1IAD A;  3K7N A;  1YP1 A;  4PKR A;  2D1N A;  5D1S A;  1QIA A;  2MLR A;  4XM8 A;  1EAK A;  3V96 B;  1GXD A;  1BUD A;  1JJ9 A;  2K2G A;  5CUH A;  1HV5 A;  1C3I A;  1GKC A;  1PWP A;  2OVZ A;  1BKC I;  1SMP A;  4QKZ A;  1IAE A;  1G12 A;  4XBH A;  4I03 A;  4DV8 A;  1CIZ A;  1AYK A;  1XFW A;  830C A;  4AYK A;  3LJZ A;  1RM8 A;  1OM6 A;  2JNP A;  1JIW P;  1IAC A;  1O0T A;  1BQQ M;  4PKS A;  1AKL A;  2ERP A;  1ZXV A;  4G9L A;  3E8R A;  1OO9 A;  3B8Z A;  2DW1 A;  5CZM A;  1UMS A;  1Q3A A;  2FV5 A;  4PKQ A;  2DDF A;  2MZI A;  5I12 A;  3SHI A;  1B8Y A;  2HU6 A;  1JKY A;  1GO7 P;  3I7I A;  1Z3J A;  4I35 A;  1JIZ A;  1G05 A;  2FV9 A;  1R54 A;  1DMT A;  3HDA P;  1XUR A;  3OHL A;  4HMA A;  1HFS A;  2I47 A;  4L63 A;  4CTH A;  2TCL A;  4R3V A;  1SLM A;  4JP4 A;  3TS4 A;  4JPA A;  2JSD A;  4PKT A;  4FXQ A;  4WZV A;  2DW2 A;  1OS9 A;  2ERQ A;  1DTH A;  2N8R A;  1GE7 A;  4ZR5 A;  3AYU A;  3UVC A;  4ILW D;  5LAB A;  4Q1L A;  2Z2D A;  1YOU A;  3ELM A;  1USN A;  3CKI A;  1HY7 A;  5BOY A;  2D1O A;  2USN A;  1CAQ A;  3F15 A;  1XFX A;  3HYG A;  1S4B P;  5D7W A;  1SU3 A;  1PWV A;  1G4K A;  2OW1 A;  1CK7 A;  2OZR A;  1MMR A;  5I43 A;  1SAT A;  4L6T A;  3TT4 A;  2XS3 A;  1JH1 A;  2MLS A;  1ZTQ A;  2W14 A;  1HOV A;  2X7M A;  3DPE A;  1ZP5 A;  4GWM A;  3LKA A;  3HBV P;  2W0D A;  4WF6 A;  2PJT A;  3LK8 A;  4GR0 A;  1H71 P;  5CXA A;  2Y6C A;  2K9C A;  5BOT A;  1GKD A;  4AIG A;  4L19 A;  2MZH A;  3P24 A;  2DDY A;  4H84 A;  1GE6 A;  1UEA A;  4IJO A;  456C A;  2OXZ A;  4DF9 A;  1IAG A;  5JMY A;  1XFV A;  3ZUK A;  2JT6 A;  1KBC A;  1OS2 A;  1AST A;  1JAQ A;  1ZXC A;  1IAB A;  1I76 A;  2XS4 A;  3LEA A;  4JA1 A;  4A7B A;  3WV3 A;  2RJQ A;  3NX7 A;  1PWU A;  1FBL A;  1GO8 P;  1B3D A;  3L0T A;  1EB6 A;  4G0D A;  4IN9 A;  1KUG A;  3LQ0 A;  1JAO A;  4FVL A;  2W13 A;  4A3W A;  1ROS A;  3EDI A;  1BUV M;  1HTD A;  5I4O A;  2MZE A;  2WO9 A;  1CGF A;  1G9K A;  3G5C A;  1PWQ A;  1K7I A;  1FM1 A;  4H1Q A;  5D1T A;  1MMQ A;  1XFU A;  4GF1 A;  3HY7 A;  3F1A A;  1CGE A;  1D8F A;  1J7N A;  1CXV A;  4H82 A;  5D2B A;  3WV1 A;  2SRT A;  3O2X A;  5I3M A;  1OMJ A;  3KME A;  1XFY A;  1K7G A;  1MMP A;  1JAN A;  2O3E A;  1JK3 A;  1BZS A;  4H2E A;  2OI0 A;  1BKC E;  1IAA A;  1G49 A;  1MMB A;  1UMT A;  2OW0 A;  3N2V A;  1KAP P;  3TSK A;  1XUC A;  3G42 A;  2J83 A;  1Y93 A;  1MNC A;  2Y6D A;  2X3A A;  4GR3 A;  4XM7 A;  2W15 A;  3BA0 A;  3LE9 A;  4DPE A;  2WOA A;  5B5O A;  1QIC A;  3VI1 A;  1OM7 A;  1SRP A;  2A8H A;  4PKU A;  2OVX A;  1A85 A;  4HX3 A;  1KUF A;  4J4M A;  4GR8 A;  3KWV C;  3LJG A;  3EDG A;  3K7L A;  3B2Z A;  2O36 A;  3P1V A;  3KRY A;  1KUI A;  2OXU A;  2L0R A;  1UTZ A;  3EHX A;  5L7F A;  3LMC A;  1D5J A;  2E2D A;  1BKC A;  4XM6 A;  1KUK A;  3HB2 P;  4FU4 A;  1BIW A;  4AXQ A;  4WK7 A;  2OY4 A;  3F17 A;  2W12 A;  3LIK A;  2QPJ A;  1K7Q A;  3RTT A;  5I2Z A;  1OM8 A;  4H30 A;  3EWJ A;  1R1J A;  3HDB A;  3U1R A;  4JIJ A;  1FLS A;  3LUN A;  5BPA A;  2YIG A;  3KHI A;  3LJT A;  1XFZ A;  1I73 A;  3N2U A;  1BM6 A;  3LIL A;  5L79 A;  4DD8 A;  3DPF A;  1D7X A;  4ON1 A;  2KRJ A;  2J0T A;  3WV2 A;  4H3X A;  1CQR A;  3HBU P;  1ND1 A;  2CLT A;  3F16 A;  1JAP A;  5I0L A;  1QJJ A;  1I1I P;  4FXY P;  4PKW A;  1R55 A;  5D1U A;  2V4B A;  3KEJ A; 
#chains in the Genus database with same CATH topology
 3AIG A;  1A86 A;  2CKI A;  1RMZ A;  4XCT A;  1QJI A;  2OW2 A;  1GE5 A;  1O0Q A;  5D3C A;  2WO8 A;  1BQO A;  1CGL A;  3EDH A;  3LGP A;  1XUD A;  3DWB A;  1YQY A;  1SLN A;  1Y8J A;  4JQG A;  3LUM A;  1KUH A;  3O64 A;  4GWN A;  3KMC A;  4H76 A;  2E3X A;  3F18 A;  3KEC A;  1EUB A;  1ZS0 A;  1C8T A;  1R1H A;  2AIG P;  4GUY A;  4PKV A;  4EFS A;  3LIR A;  4GQL A;  2JT5 A;  2OW9 A;  3GBO A;  3AYK A;  2ERO A;  2DW0 A;  3ZVS A;  3OHO A;  1D8M A;  4WKI A;  1Y0V A;  3LQB A;  2YB9 A;  3VTG A;  3F19 A;  1R1I A;  3MA2 A;  1PWW A;  2X3C A;  3EHY A;  1AF0 A;  1BSW A;  2JIH A;  1ZVX A;  3L0V A;  1QUA A;  3DNG A;  3EDZ A;  4AUO A;  1C7K A;  3DSL A;  2RJP A;  3ZXH A;  4WKE A;  3HY9 A;  1QIB A;  4IUW A;  4H49 A;  3KEK A;  2OXW A;  3TVC A;  1ATL A;  5B5P A;  1WNI A;  3B92 A;  1L6J A;  2OY2 A;  2AYK A;  1HFC A;  1YCM A;  3DL1 A;  1UTT A;  2X3B A;  2POJ A;  3Q2H A;  3Q2G A;  3RTS A;  3I7G A;  5H8X A;  3USN A;  966C A;  1IAD A;  3K7N A;  1YP1 A;  4PKR A;  2D1N A;  5D1S A;  1QIA A;  2MLR A;  4XM8 A;  1EAK A;  3V96 B;  3DTE A;  1GXD A;  1BUD A;  1JJ9 A;  2K2G A;  5CUH A;  1HV5 A;  1C3I A;  1GKC A;  1PWP A;  2OVZ A;  1BKC I;  1OZ9 A;  1SMP A;  4QKZ A;  1IAE A;  1G12 A;  4XBH A;  4I03 A;  4DV8 A;  1CIZ A;  1AYK A;  4L7A A;  1XFW A;  830C A;  1TVI A;  4AYK A;  3LJZ A;  1RM8 A;  1OM6 A;  2JNP A;  1JIW P;  1IAC A;  1O0T A;  1BQQ M;  4PKS A;  1AKL A;  2ERP A;  1ZXV A;  4G9L A;  3E8R A;  1OO9 A;  1XM5 A;  3B8Z A;  2DW1 A;  5CZM A;  1UMS A;  1Q3A A;  2FV5 A;  4PKQ A;  2DDF A;  2MZI A;  5I12 A;  3SHI A;  1B8Y A;  2HU6 A;  1JKY A;  1GO7 P;  3I7I A;  1Z3J A;  4I35 A;  1JIZ A;  1G05 A;  2FV9 A;  1R54 A;  1DMT A;  3HDA P;  1XUR A;  3OHL A;  4HMA A;  1HFS A;  2I47 A;  4L63 A;  4CTH A;  2TCL A;  4R3V A;  1SLM A;  4JP4 A;  3TS4 A;  4JPA A;  2JSD A;  4PKT A;  4FXQ A;  4WZV A;  2DW2 A;  1OS9 A;  2ERQ A;  1DTH A;  2N8R A;  1GE7 A;  4ZR5 A;  3AYU A;  3UVC A;  4ILW D;  5LAB A;  4Q1L A;  2Z2D A;  1YOU A;  3ELM A;  1USN A;  3CKI A;  1HY7 A;  5BOY A;  2D1O A;  2USN A;  1CAQ A;  3F15 A;  1XFX A;  3HYG A;  1S4B P;  5D7W A;  1SU3 A;  1PWV A;  1G4K A;  2OW1 A;  1CK7 A;  2OZR A;  1MMR A;  5I43 A;  1SAT A;  4L6T A;  3TT4 A;  2XS3 A;  1JH1 A;  2MLS A;  3DTI A;  1ZTQ A;  2W14 A;  1HOV A;  2X7M A;  3DPE A;  1ZP5 A;  4GWM A;  3LKA A;  3HBV P;  2W0D A;  4WF6 A;  2PJT A;  3LK8 A;  4GR0 A;  1H71 P;  5CXA A;  2Y6C A;  2K9C A;  5BOT A;  1GKD A;  4AIG A;  4L19 A;  2MZH A;  3P24 A;  2DDY A;  4H84 A;  1GE6 A;  1UEA A;  4IJO A;  456C A;  2OXZ A;  4DF9 A;  1IAG A;  5JMY A;  1XFV A;  3ZUK A;  2JT6 A;  1KBC A;  1OS2 A;  1AST A;  1JAQ A;  1ZXC A;  1IAB A;  1I76 A;  2XS4 A;  3LEA A;  4JA1 A;  4A7B A;  3WV3 A;  2RJQ A;  3NX7 A;  1PWU A;  3DTK A;  1FBL A;  1GO8 P;  1B3D A;  3L0T A;  1EB6 A;  4G0D A;  4IN9 A;  1KUG A;  3LQ0 A;  1JAO A;  4FVL A;  2W13 A;  4A3W A;  1ROS A;  3EDI A;  1BUV M;  1HTD A;  5I4O A;  2MZE A;  2WO9 A;  1CGF A;  1G9K A;  3G5C A;  1PWQ A;  1K7I A;  1FM1 A;  4H1Q A;  5D1T A;  1MMQ A;  1XFU A;  4GF1 A;  3HY7 A;  3F1A A;  1CGE A;  1D8F A;  1J7N A;  1CXV A;  4H82 A;  5D2B A;  3WV1 A;  2SRT A;  3O2X A;  5I3M A;  1OMJ A;  3KME A;  1XFY A;  1K7G A;  1MMP A;  1JAN A;  2O3E A;  1JK3 A;  1BZS A;  4H2E A;  2OI0 A;  1BKC E;  1IAA A;  1G49 A;  1MMB A;  1UMT A;  2OW0 A;  3N2V A;  1KAP P;  3TSK A;  1XUC A;  3G42 A;  2J83 A;  1Y93 A;  1MNC A;  2Y6D A;  2X3A A;  4GR3 A;  4XM7 A;  2W15 A;  3BA0 A;  3LE9 A;  4DPE A;  2WOA A;  5B5O A;  1QIC A;  3VI1 A;  1OM7 A;  1SRP A;  2A8H A;  4PKU A;  2OVX A;  1A85 A;  4HX3 A;  1KUF A;  4J4M A;  4GR8 A;  3KWV C;  3LJG A;  3EDG A;  3K7L A;  3B2Z A;  2O36 A;  3P1V A;  3KRY A;  1XAX A;  1KUI A;  2OXU A;  2L0R A;  1UTZ A;  3EHX A;  5L7F A;  3LMC A;  1D5J A;  2E2D A;  1BKC A;  4XM6 A;  1KUK A;  3HB2 P;  4FU4 A;  1BIW A;  4AXQ A;  4WK7 A;  2OY4 A;  3F17 A;  2W12 A;  3LIK A;  2QPJ A;  1K7Q A;  3RTT A;  5I2Z A;  1OM8 A;  4H30 A;  3EWJ A;  3HDB A;  1R1J A;  2YUF A;  3U1R A;  4JIJ A;  1FLS A;  3LUN A;  5BPA A;  2YIG A;  3KHI A;  3LJT A;  1XFZ A;  1I73 A;  3N2U A;  1BM6 A;  3LIL A;  5L79 A;  4DD8 A;  3DPF A;  1D7X A;  4ON1 A;  2KRJ A;  2J0T A;  3WV2 A;  4H3X A;  1CQR A;  3HBU P;  1ND1 A;  2CLT A;  3F16 A;  1JAP A;  5I0L A;  1QJJ A;  1I1I P;  4FXY P;  4PKW A;  1R55 A;  5D1U A;  2V4B A;  3KEJ A; 
#chains in the Genus database with same CATH homology
 3AIG A;  1A86 A;  2CKI A;  1RMZ A;  4XCT A;  1QJI A;  2OW2 A;  1GE5 A;  1O0Q A;  5D3C A;  2WO8 A;  1BQO A;  1CGL A;  3EDH A;  3LGP A;  1XUD A;  3DWB A;  1YQY A;  1SLN A;  1Y8J A;  4JQG A;  3LUM A;  1KUH A;  3O64 A;  4GWN A;  3KMC A;  4H76 A;  2E3X A;  3F18 A;  3KEC A;  1EUB A;  1ZS0 A;  1C8T A;  1R1H A;  2AIG P;  4GUY A;  4PKV A;  4EFS A;  3LIR A;  4GQL A;  2JT5 A;  2OW9 A;  3GBO A;  3AYK A;  2ERO A;  2DW0 A;  3ZVS A;  3OHO A;  1D8M A;  4WKI A;  1Y0V A;  3LQB A;  2YB9 A;  3VTG A;  3F19 A;  1R1I A;  3MA2 A;  1PWW A;  2X3C A;  3EHY A;  1AF0 A;  1BSW A;  2JIH A;  1ZVX A;  3L0V A;  1QUA A;  3DNG A;  3EDZ A;  4AUO A;  1C7K A;  3DSL A;  2RJP A;  3ZXH A;  4WKE A;  3HY9 A;  1QIB A;  4IUW A;  4H49 A;  3KEK A;  2OXW A;  3TVC A;  1ATL A;  5B5P A;  1WNI A;  3B92 A;  1L6J A;  2OY2 A;  2AYK A;  1HFC A;  1YCM A;  3DL1 A;  1UTT A;  2X3B A;  2POJ A;  3Q2H A;  3Q2G A;  3RTS A;  3I7G A;  5H8X A;  3USN A;  966C A;  1IAD A;  3K7N A;  1YP1 A;  4PKR A;  2D1N A;  5D1S A;  1QIA A;  2MLR A;  4XM8 A;  1EAK A;  3V96 B;  3DTE A;  1GXD A;  1BUD A;  1JJ9 A;  2K2G A;  5CUH A;  1HV5 A;  1C3I A;  1GKC A;  1PWP A;  2OVZ A;  1BKC I;  1SMP A;  4QKZ A;  1IAE A;  1G12 A;  4XBH A;  4I03 A;  4DV8 A;  1CIZ A;  1AYK A;  4L7A A;  1XFW A;  830C A;  4AYK A;  3LJZ A;  1RM8 A;  1OM6 A;  2JNP A;  1JIW P;  1IAC A;  1O0T A;  1BQQ M;  4PKS A;  1AKL A;  2ERP A;  1ZXV A;  4G9L A;  3E8R A;  1OO9 A;  3B8Z A;  2DW1 A;  5CZM A;  1UMS A;  1Q3A A;  2FV5 A;  4PKQ A;  2DDF A;  2MZI A;  5I12 A;  3SHI A;  1B8Y A;  2HU6 A;  1JKY A;  1GO7 P;  3I7I A;  1Z3J A;  4I35 A;  1JIZ A;  1G05 A;  2FV9 A;  1R54 A;  1DMT A;  3HDA P;  1XUR A;  3OHL A;  4HMA A;  1HFS A;  2I47 A;  4L63 A;  4CTH A;  2TCL A;  4R3V A;  1SLM A;  4JP4 A;  3TS4 A;  4JPA A;  2JSD A;  4PKT A;  4FXQ A;  4WZV A;  2DW2 A;  1OS9 A;  2ERQ A;  1DTH A;  2N8R A;  1GE7 A;  4ZR5 A;  3AYU A;  3UVC A;  4ILW D;  5LAB A;  4Q1L A;  2Z2D A;  1YOU A;  3ELM A;  1USN A;  3CKI A;  1HY7 A;  5BOY A;  2D1O A;  2USN A;  1CAQ A;  3F15 A;  1XFX A;  3HYG A;  1S4B P;  5D7W A;  1SU3 A;  1PWV A;  1G4K A;  2OW1 A;  1CK7 A;  2OZR A;  1MMR A;  5I43 A;  1SAT A;  4L6T A;  3TT4 A;  2XS3 A;  1JH1 A;  2MLS A;  3DTI A;  1ZTQ A;  2W14 A;  1HOV A;  2X7M A;  3DPE A;  1ZP5 A;  4GWM A;  3LKA A;  3HBV P;  2W0D A;  4WF6 A;  2PJT A;  3LK8 A;  4GR0 A;  1H71 P;  5CXA A;  2Y6C A;  2K9C A;  5BOT A;  1GKD A;  4AIG A;  4L19 A;  2MZH A;  3P24 A;  2DDY A;  4H84 A;  1GE6 A;  1UEA A;  4IJO A;  456C A;  2OXZ A;  4DF9 A;  1IAG A;  5JMY A;  1XFV A;  3ZUK A;  2JT6 A;  1KBC A;  1OS2 A;  1AST A;  1JAQ A;  1ZXC A;  1IAB A;  1I76 A;  2XS4 A;  3LEA A;  4JA1 A;  4A7B A;  3WV3 A;  2RJQ A;  3NX7 A;  1PWU A;  3DTK A;  1FBL A;  1GO8 P;  1B3D A;  3L0T A;  1EB6 A;  4G0D A;  4IN9 A;  1KUG A;  3LQ0 A;  1JAO A;  4FVL A;  2W13 A;  4A3W A;  1ROS A;  3EDI A;  1BUV M;  1HTD A;  5I4O A;  2MZE A;  2WO9 A;  1CGF A;  1G9K A;  3G5C A;  1PWQ A;  1K7I A;  1FM1 A;  4H1Q A;  5D1T A;  1MMQ A;  1XFU A;  4GF1 A;  3HY7 A;  3F1A A;  1CGE A;  1D8F A;  1J7N A;  1CXV A;  4H82 A;  5D2B A;  3WV1 A;  2SRT A;  3O2X A;  5I3M A;  1OMJ A;  3KME A;  1XFY A;  1K7G A;  1MMP A;  1JAN A;  2O3E A;  1JK3 A;  1BZS A;  4H2E A;  2OI0 A;  1BKC E;  1IAA A;  1G49 A;  1MMB A;  1UMT A;  2OW0 A;  3N2V A;  1KAP P;  3TSK A;  1XUC A;  3G42 A;  2J83 A;  1Y93 A;  1MNC A;  2Y6D A;  2X3A A;  4GR3 A;  4XM7 A;  2W15 A;  3BA0 A;  3LE9 A;  4DPE A;  2WOA A;  5B5O A;  1QIC A;  3VI1 A;  1OM7 A;  1SRP A;  2A8H A;  4PKU A;  2OVX A;  1A85 A;  4HX3 A;  1KUF A;  4J4M A;  4GR8 A;  3KWV C;  3LJG A;  3EDG A;  3K7L A;  3B2Z A;  2O36 A;  3P1V A;  3KRY A;  1KUI A;  2OXU A;  2L0R A;  1UTZ A;  3EHX A;  5L7F A;  3LMC A;  1D5J A;  2E2D A;  1BKC A;  4XM6 A;  1KUK A;  3HB2 P;  4FU4 A;  1BIW A;  4AXQ A;  4WK7 A;  2OY4 A;  3F17 A;  2W12 A;  3LIK A;  2QPJ A;  1K7Q A;  3RTT A;  5I2Z A;  1OM8 A;  4H30 A;  3EWJ A;  3HDB A;  1R1J A;  2YUF A;  3U1R A;  4JIJ A;  1FLS A;  3LUN A;  5BPA A;  2YIG A;  3KHI A;  3LJT A;  1XFZ A;  1I73 A;  3N2U A;  1BM6 A;  3LIL A;  5L79 A;  4DD8 A;  3DPF A;  1D7X A;  4ON1 A;  2KRJ A;  2J0T A;  3WV2 A;  4H3X A;  1CQR A;  3HBU P;  1ND1 A;  2CLT A;  3F16 A;  1JAP A;  5I0L A;  1QJJ A;  1I1I P;  4FXY P;  4PKW A;  1R55 A;  5D1U A;  2V4B A;  3KEJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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