1ZXCA

Crystal structure of catalytic domain of tnf-alpha converting enzyme (tace) with inhibitor
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
259
structure length
259
Chain Sequence
DPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Acetylenic TACE inhibitors. Part 2: SAR of six-membered cyclic sulfonamide hydroxamates.
pubmed doi rcsb
molecule keywords ADAM 17
total genus 87
structure length 259
sequence length 259
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2005-06-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1zxcA00
4G9LA 1QJJA 1OM8A 3OHLA 1PWQA 1JK3A 3LJTA 4PKSA 3NX7A 2OZRA 1SATA 3G5CA 1I76A 3V96B 4L19A 1GKCA 1XFZA 2W14A 3HB2P 1XFVA 1Y0VA 2K9CA 5I0LA 1BUVM 1D8FA 1CGLA 1PWVA 5D1TA 2W12A 3RTTA 1ZXVA 1XUDA 4PKVA 1DTHA 1HY7A 1CGFA 2L0RA 2WOAA 2MZHA 5L7FA 4GUYA 3USNA 3TVCA 1ZXCA 3ZUKA 1BZSA 2A8HA 4H49A 1YP1A 2WO8A 4H82A 3O2XA 4PKQA 3LMCA 1PWUA 1O0QA 5BOTA 1FBLA 2YB9A 4GR3A 2X7MA 1GE5A 3EHYA 1WNIA 2POJA 2OVZA 4DF9A 1R55A 1UMSA 1OS2A 1FM1A 1MMQA 2DDFA 2OW0A 3VI1A 1QJIA 2N8RA 2OXWA 2ERQA 1UTTA 3AIGA 3AYKA 1RM8A 2FV5A 1Q3AA 4JA1A 1R1IA 2X3AA 3EHXA 5JMYA 3LQBA 2W0DA 3LEAA 2K2GA 2QPJA 3F15A 1MMRA 1K7QA 1XFYA 4GWMA 3UVCA 1C8TA 1HV5A 1IACA 3F17A 1G4KA 2DDYA 2Y6DA 4DD8A 1JIWP 2USNA 4FVLA 1GE6A 1HOVA 1QIAA 1GXDA 1BKCE 1UMTA 2YIGA 1AF0A 3HYGA 2XS3A 1QUAA 1GKDA 4Q1LA 1BSWA 3F19A 4JP4A 4XCTA 1CGEA 4H30A 1YQYA 5D7WA 1SU3A 1XFWA 3OHOA 1Y93A 1KUIA 1JKYA 1ZVXA 3DL1A 1MMPA 2D1NA 3O64A 2HU6A 3WV1A 1YCMA 2MZEA 3DSLA 3F16A 3DPEA 3L0TA 1R54A 1XFUA 1OO9A 5H8XA 3LE9A 1CK7A 4HX3A 2I47A 1L6JA 1R1HA 3WV3A 3Q2GA 1HFSA 4GWNA 3HY9A 1PWPA 4ILWD 1IAAA 1AYKA 3HY7A 3U1RA 5BPAA 4XM8A 1CXVA 1EAKA 3DPFA 4J4MA 2JNPA 3LGPA 5I4OA 2Z2DA 1USNA 1B3DA 5I2ZA 1SLMA 2AYKA 1UTZA 3RTSA 1I73A 1J7NA 4GR8A 4H76A 1OS9A 3LKAA 4GQLA 4AYKA 2OW1A 1A86A 1MMBA 1G05A 3CKIA 2J83A 1KBCA 1BQQM 1CAQA 1JANA 4PKRA 3LUNA 1C7KA 5CUHA 3KMCA 3TSKA 1Y8JA 5B5PA 5LABA 1OM7A 3LILA 1KUFA 1BKCA 1CQRA 1QIBA 5BOYA 3B8ZA 3N2VA 3KEJA 1I1IP 2SRTA 3F18A 4JIJA 1BKCI 3BA0A 4R3VA 2PJTA 4WK7A 1ASTA 4IN9A 1G12A 5D1SA 3G42A 2CLTA 3VTGA 3KRYA 1SMPA 4G0DA 2W15A 4WF6A 2DW1A 1OM6A 4PKTA 3DWBA 3KHIA 1ZS0A 1DMTA 5D2BA 2MLSA 2XS4A 3P1VA 4PKUA 3WV2A 1BUDA 1Z3JA 3MA2A 1XUCA 1R1JA 3N2UA 2AIGP 3KMEA 2DW2A 4JPAA 966CA 3HDBA 5L79A 2OY4A 2WO9A 3KWVC 5D1UA 4HMAA 1XFXA 2FV9A 3TS4A 1JJ9A 1JH1A 2J0TA 1BQOA 3KECA 1ND1A 4DV8A 2ERPA 2OXZA 3Q2HA 3HBUP 1GE7A 4ON1A 1XURA 1JIZA 3P24A 4WKEA 1IAEA 1G49A 2JT5A 1GO8P 1H71P 1JAOA 1BM6A 2TCLA 1YOUA 1AKLA 1GO7P 4IJOA 1D8MA 1MNCA 4AXQA 3GBOA 1FLSA 1SLNA 4JQGA 3ZXHA 4XM6A 1O0TA 2EROA 3SHIA 4XBHA 1IABA 2X3CA 1RMZA 1K7GA 2O36A 5I43A 2X3BA 1S4BP 2OY2A 4GR0A 2E3XA 1OMJA 1D7XA 5CXAA 2JIHA 5B5OA 4FXYP 4DPEA 456CA 1BIWA 3EDGA 1C3IA 3LQ0A 2MLRA 3F1AA 4I03A 2CKIA 4H3XA 1B8YA 4ZR5A 1KAPP 4L63A 4FXQA 1KUHA 2OI0A 4WKIA 4A7BA 3LUMA 4FU4A 4XM7A 1JAQA 5D3CA 4I35A 4L6TA 2MZIA 1EB6A 2W13A 1A85A 2OW2A 2Y6CA 1HTDA 3LJZA 3L0VA 3EWJA 2D1OA 2KRJA 4CTHA 1ZTQA 2V4BA 1G9KA 3DNGA 2RJPA 3HBVP 4A3WA 3KEKA 3B2ZA 4IUWA 4H2EA 3LIRA 3I7IA 4QKZA 1CIZA 1KUKA 3LK8A 4H84A 1IADA 1KUGA 5I3MA 1K7IA 2RJQA 1SRPA 3K7LA 4EFSA 3TT4A 1IAGA 1EUBA 3LIKA 2DW0A 1D5JA 4AIGA 3K7NA 4WZVA 3E8RA 2OW9A 3EDHA 2E2DA 830CA 2OXUA 1QICA 3I7GA 1ZP5A 1ROSA 5CZMA 4PKWA 4GF1A 2O3EA 3B92A 2JSDA 3EDZA 3ZVSA 4AUOA 1PWWA 1HFCA 3HDAP 3LJGA 3ELMA 2OVXA 1ATLA 3AYUA 1UEAA 5I12A 2JT6A 3EDIA 4H1QA 1JAPA
chains in the Genus database with same CATH superfamily
4G9LA 1QJJA 1OM8A 3OHLA 1PWQA 1JK3A 3LJTA 4PKSA 3NX7A 2OZRA 1SATA 3G5CA 1I76A 3V96B 4L19A 1GKCA 1XFZA 2W14A 3HB2P 1XFVA 1Y0VA 2K9CA 5I0LA 1BUVM 1D8FA 1CGLA 1PWVA 5D1TA 1XM5A 2W12A 3RTTA 1ZXVA 1XUDA 4PKVA 1DTHA 1HY7A 1CGFA 2L0RA 2WOAA 2MZHA 5L7FA 4GUYA 3USNA 3TVCA 1ZXCA 3ZUKA 1BZSA 2A8HA 4H49A 1YP1A 2WO8A 4H82A 3O2XA 4L7AA 4PKQA 3LMCA 1PWUA 1O0QA 5BOTA 1FBLA 2YB9A 4GR3A 2X7MA 1GE5A 3EHYA 1WNIA 2POJA 2OVZA 4DF9A 1R55A 1UMSA 1OS2A 1FM1A 1MMQA 2DDFA 2OW0A 3VI1A 1QJIA 2N8RA 2OXWA 2ERQA 1UTTA 3AIGA 3AYKA 1RM8A 2FV5A 1Q3AA 4JA1A 1R1IA 2X3AA 3EHXA 5JMYA 3LQBA 2W0DA 3LEAA 2K2GA 2QPJA 3F15A 1MMRA 1K7QA 1XFYA 4GWMA 3UVCA 1C8TA 1HV5A 1IACA 3F17A 1G4KA 2DDYA 2Y6DA 4DD8A 1JIWP 2USNA 4FVLA 1GE6A 1HOVA 1QIAA 1GXDA 1BKCE 1UMTA 2YIGA 1AF0A 3HYGA 2XS3A 1QUAA 1GKDA 4Q1LA 1BSWA 3F19A 4JP4A 4XCTA 1CGEA 4H30A 1YQYA 5D7WA 1SU3A 1XFWA 3OHOA 1Y93A 1KUIA 1JKYA 1ZVXA 3DL1A 1MMPA 2D1NA 3O64A 2HU6A 3WV1A 1YCMA 2MZEA 3DSLA 3F16A 3DPEA 3L0TA 1R54A 1XFUA 1OO9A 5H8XA 3LE9A 1CK7A 4HX3A 2I47A 1L6JA 1R1HA 3WV3A 3Q2GA 1HFSA 4GWNA 3HY9A 1PWPA 4ILWD 1IAAA 1AYKA 3HY7A 3U1RA 5BPAA 4XM8A 1CXVA 1EAKA 3DPFA 4J4MA 2JNPA 3LGPA 5I4OA 2Z2DA 1USNA 1B3DA 5I2ZA 1SLMA 2AYKA 1UTZA 3RTSA 1I73A 1J7NA 4GR8A 4H76A 1OS9A 3LKAA 4GQLA 4AYKA 2OW1A 1A86A 1MMBA 1G05A 3CKIA 2J83A 1KBCA 1BQQM 1CAQA 1JANA 4PKRA 3LUNA 1C7KA 5CUHA 3KMCA 3TSKA 1Y8JA 5B5PA 5LABA 1OM7A 3LILA 1KUFA 1BKCA 1CQRA 1QIBA 5BOYA 3B8ZA 3N2VA 3KEJA 1I1IP 2SRTA 3F18A 4JIJA 1BKCI 3BA0A 4R3VA 2PJTA 4WK7A 1ASTA 4IN9A 1G12A 5D1SA 3G42A 2CLTA 3VTGA 3DTIA 3KRYA 1SMPA 4G0DA 2W15A 4WF6A 2DW1A 1OM6A 4PKTA 3DWBA 3KHIA 1ZS0A 1DMTA 5D2BA 2MLSA 2XS4A 3P1VA 4PKUA 3WV2A 1BUDA 1Z3JA 3MA2A 1XUCA 1R1JA 3N2UA 2AIGP 3KMEA 2DW2A 4JPAA 966CA 3HDBA 5L79A 2OY4A 2WO9A 3KWVC 5D1UA 3DTKA 4HMAA 1XFXA 2FV9A 3TS4A 1JJ9A 1JH1A 2J0TA 1BQOA 3KECA 1ND1A 4DV8A 2ERPA 2OXZA 1TVIA 3Q2HA 3HBUP 1GE7A 4ON1A 1XURA 1JIZA 3P24A 4WKEA 1IAEA 1G49A 2JT5A 1GO8P 1H71P 1JAOA 1BM6A 2TCLA 1YOUA 1AKLA 1GO7P 4IJOA 1D8MA 1MNCA 4AXQA 3GBOA 1FLSA 1SLNA 4JQGA 3ZXHA 4XM6A 1O0TA 2EROA 3SHIA 4XBHA 1IABA 2X3CA 1RMZA 1K7GA 2O36A 5I43A 2X3BA 1S4BP 2OY2A 4GR0A 2E3XA 1OMJA 1D7XA 5CXAA 2JIHA 5B5OA 4FXYP 4DPEA 456CA 1BIWA 3EDGA 1C3IA 3LQ0A 2MLRA 3F1AA 4I03A 2YUFA 2CKIA 4H3XA 1B8YA 1OZ9A 4ZR5A 1KAPP 4L63A 4FXQA 1KUHA 2OI0A 4WKIA 4A7BA 3LUMA 4FU4A 4XM7A 1JAQA 5D3CA 4I35A 4L6TA 2MZIA 1EB6A 2W13A 1A85A 2OW2A 2Y6CA 1HTDA 3LJZA 3L0VA 3EWJA 2D1OA 2KRJA 4CTHA 1ZTQA 2V4BA 1G9KA 3DNGA 2RJPA 3HBVP 4A3WA 3KEKA 3B2ZA 4IUWA 4H2EA 3LIRA 3I7IA 4QKZA 1CIZA 1KUKA 3LK8A 4H84A 1IADA 1KUGA 5I3MA 1K7IA 2RJQA 1SRPA 3K7LA 4EFSA 3TT4A 1IAGA 1EUBA 3LIKA 2DW0A 1D5JA 4AIGA 3K7NA 4WZVA 3E8RA 2OW9A 3EDHA 2E2DA 1XAXA 830CA 2OXUA 1QICA 3I7GA 1ZP5A 1ROSA 5CZMA 4PKWA 4GF1A 3DTEA 2O3EA 3B92A 2JSDA 3EDZA 3ZVSA 4AUOA 1PWWA 1HFCA 3HDAP 3LJGA 3ELMA 2OVXA 1ATLA 3AYUA 1UEAA 5I12A 2JT6A 3EDIA 4H1QA 1JAPA
chains in the Genus database with same CATH topology
4G9LA 1QJJA 1OM8A 3OHLA 1PWQA 1JK3A 3LJTA 4PKSA 3NX7A 2OZRA 1SATA 3G5CA 1I76A 3V96B 4L19A 1GKCA 1XFZA 2W14A 3HB2P 1XFVA 1Y0VA 2K9CA 5I0LA 1BUVM 1D8FA 1CGLA 1PWVA 5D1TA 2W12A 3RTTA 1ZXVA 1XUDA 4PKVA 1DTHA 1HY7A 1CGFA 2L0RA 2WOAA 2MZHA 5L7FA 4GUYA 3USNA 3TVCA 1ZXCA 3ZUKA 1BZSA 2A8HA 4H49A 1YP1A 2WO8A 4H82A 3O2XA 4L7AA 4PKQA 3LMCA 1PWUA 1O0QA 5BOTA 1FBLA 2YB9A 4GR3A 2X7MA 1GE5A 3EHYA 1WNIA 2POJA 2OVZA 4DF9A 1R55A 1UMSA 1OS2A 1FM1A 1MMQA 2DDFA 2OW0A 3VI1A 1QJIA 2N8RA 2OXWA 2ERQA 1UTTA 3AIGA 3AYKA 1RM8A 2FV5A 1Q3AA 4JA1A 1R1IA 2X3AA 3EHXA 5JMYA 3LQBA 2W0DA 3LEAA 2K2GA 2QPJA 3F15A 1MMRA 1K7QA 1XFYA 4GWMA 3UVCA 1C8TA 1HV5A 1IACA 3F17A 1G4KA 2DDYA 2Y6DA 4DD8A 1JIWP 2USNA 4FVLA 1GE6A 1HOVA 1QIAA 1GXDA 1BKCE 1UMTA 2YIGA 1AF0A 3HYGA 2XS3A 1QUAA 1GKDA 4Q1LA 1BSWA 3F19A 4JP4A 4XCTA 1CGEA 4H30A 1YQYA 5D7WA 1SU3A 1XFWA 3OHOA 1Y93A 1KUIA 1JKYA 1ZVXA 3DL1A 1MMPA 2D1NA 3O64A 2HU6A 3WV1A 1YCMA 2MZEA 3DSLA 3F16A 3DPEA 3L0TA 1R54A 1XFUA 1OO9A 5H8XA 3LE9A 1CK7A 4HX3A 2I47A 1L6JA 1R1HA 3WV3A 3Q2GA 1HFSA 4GWNA 3HY9A 1PWPA 4ILWD 1IAAA 1AYKA 3HY7A 3U1RA 5BPAA 4XM8A 1CXVA 1EAKA 3DPFA 4J4MA 2JNPA 3LGPA 5I4OA 2Z2DA 1USNA 1B3DA 5I2ZA 1SLMA 2AYKA 1UTZA 3RTSA 1I73A 1J7NA 4GR8A 4H76A 1OS9A 3LKAA 4GQLA 4AYKA 2OW1A 1A86A 1MMBA 1G05A 3CKIA 2J83A 1KBCA 1BQQM 1CAQA 1JANA 4PKRA 3LUNA 1C7KA 5CUHA 3KMCA 3TSKA 1Y8JA 5B5PA 5LABA 1OM7A 3LILA 1KUFA 1BKCA 1CQRA 1QIBA 5BOYA 3B8ZA 3N2VA 3KEJA 1I1IP 2SRTA 3F18A 4JIJA 1BKCI 3BA0A 4R3VA 2PJTA 4WK7A 1ASTA 4IN9A 1G12A 5D1SA 3G42A 2CLTA 3VTGA 3DTIA 3KRYA 1SMPA 4G0DA 2W15A 4WF6A 2DW1A 1OM6A 4PKTA 3DWBA 3KHIA 1ZS0A 1DMTA 5D2BA 2MLSA 2XS4A 3P1VA 4PKUA 3WV2A 1BUDA 1Z3JA 3MA2A 1XUCA 1R1JA 3N2UA 2AIGP 3KMEA 2DW2A 4JPAA 966CA 3HDBA 5L79A 2OY4A 2WO9A 3KWVC 5D1UA 3DTKA 4HMAA 1XFXA 2FV9A 3TS4A 1JJ9A 1JH1A 2J0TA 1BQOA 3KECA 1ND1A 4DV8A 2ERPA 2OXZA 3Q2HA 3HBUP 1GE7A 4ON1A 1XURA 1JIZA 3P24A 4WKEA 1IAEA 1G49A 2JT5A 1GO8P 1H71P 1JAOA 1BM6A 2TCLA 1YOUA 1AKLA 1GO7P 4IJOA 1D8MA 1MNCA 4AXQA 3GBOA 1FLSA 1SLNA 4JQGA 3ZXHA 4XM6A 1O0TA 2EROA 3SHIA 4XBHA 1IABA 2X3CA 1RMZA 1K7GA 2O36A 5I43A 2X3BA 1S4BP 2OY2A 4GR0A 2E3XA 1OMJA 1D7XA 5CXAA 2JIHA 5B5OA 4FXYP 4DPEA 456CA 1BIWA 3EDGA 1C3IA 3LQ0A 2MLRA 3F1AA 4I03A 2YUFA 2CKIA 4H3XA 1B8YA 4ZR5A 1KAPP 4L63A 4FXQA 1KUHA 2OI0A 4WKIA 4A7BA 3LUMA 4FU4A 4XM7A 1JAQA 5D3CA 4I35A 4L6TA 2MZIA 1EB6A 2W13A 1A85A 2OW2A 2Y6CA 1HTDA 3LJZA 3L0VA 3EWJA 2D1OA 2KRJA 4CTHA 1ZTQA 2V4BA 1G9KA 3DNGA 2RJPA 3HBVP 4A3WA 3KEKA 3B2ZA 4IUWA 4H2EA 3LIRA 3I7IA 4QKZA 1CIZA 1KUKA 3LK8A 4H84A 1IADA 1KUGA 5I3MA 1K7IA 2RJQA 1SRPA 3K7LA 4EFSA 3TT4A 1IAGA 1EUBA 3LIKA 2DW0A 1D5JA 4AIGA 3K7NA 4WZVA 3E8RA 2OW9A 3EDHA 2E2DA 830CA 2OXUA 1QICA 3I7GA 1ZP5A 1ROSA 5CZMA 4PKWA 4GF1A 3DTEA 2O3EA 3B92A 2JSDA 3EDZA 3ZVSA 4AUOA 1PWWA 1HFCA 3HDAP 3LJGA 3ELMA 2OVXA 1ATLA 3AYUA 1UEAA 5I12A 2JT6A 3EDIA 4H1QA 1JAPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G9L A;  1QJJ A;  1OM8 A;  3OHL A;  1PWQ A;  1JK3 A;  3LJT A;  4PKS A;  3NX7 A;  2OZR A;  1SAT A;  3G5C A;  1I76 A;  3V96 B;  4L19 A;  1GKC A;  1XFZ A;  2W14 A;  3HB2 P;  1XFV A;  1Y0V A;  2K9C A;  5I0L A;  1BUV M;  1D8F A;  1CGL A;  1PWV A;  5D1T A;  2W12 A;  3RTT A;  1ZXV A;  1XUD A;  4PKV A;  1DTH A;  1HY7 A;  1CGF A;  2L0R A;  2WOA A;  2MZH A;  5L7F A;  4GUY A;  3USN A;  3TVC A;  1ZXC A;  3ZUK A;  1BZS A;  2A8H A;  4H49 A;  1YP1 A;  2WO8 A;  4H82 A;  3O2X A;  4PKQ A;  3LMC A;  1PWU A;  1O0Q A;  5BOT A;  1FBL A;  2YB9 A;  4GR3 A;  2X7M A;  1GE5 A;  3EHY A;  1WNI A;  2POJ A;  2OVZ A;  4DF9 A;  1R55 A;  1UMS A;  1OS2 A;  1FM1 A;  1MMQ A;  2DDF A;  2OW0 A;  3VI1 A;  1QJI A;  2N8R A;  2OXW A;  2ERQ A;  1UTT A;  3AIG A;  3AYK A;  1RM8 A;  2FV5 A;  1Q3A A;  4JA1 A;  1R1I A;  2X3A A;  3EHX A;  5JMY A;  3LQB A;  2W0D A;  3LEA A;  2K2G A;  2QPJ A;  3F15 A;  1MMR A;  1K7Q A;  1XFY A;  4GWM A;  3UVC A;  1C8T A;  1HV5 A;  1IAC A;  3F17 A;  1G4K A;  2DDY A;  2Y6D A;  4DD8 A;  1JIW P;  2USN A;  4FVL A;  1GE6 A;  1HOV A;  1QIA A;  1GXD A;  1BKC E;  1UMT A;  2YIG A;  1AF0 A;  3HYG A;  2XS3 A;  1QUA A;  1GKD A;  4Q1L A;  1BSW A;  3F19 A;  4JP4 A;  4XCT A;  1CGE A;  4H30 A;  1YQY A;  5D7W A;  1SU3 A;  1XFW A;  3OHO A;  1Y93 A;  1KUI A;  1JKY A;  1ZVX A;  3DL1 A;  1MMP A;  2D1N A;  3O64 A;  2HU6 A;  3WV1 A;  1YCM A;  2MZE A;  3DSL A;  3F16 A;  3DPE A;  3L0T A;  1R54 A;  1XFU A;  1OO9 A;  5H8X A;  3LE9 A;  1CK7 A;  4HX3 A;  2I47 A;  1L6J A;  1R1H A;  3WV3 A;  3Q2G A;  1HFS A;  4GWN A;  3HY9 A;  1PWP A;  4ILW D;  1IAA A;  1AYK A;  3HY7 A;  3U1R A;  5BPA A;  4XM8 A;  1CXV A;  1EAK A;  3DPF A;  4J4M A;  2JNP A;  3LGP A;  5I4O A;  2Z2D A;  1USN A;  1B3D A;  5I2Z A;  1SLM A;  2AYK A;  1UTZ A;  3RTS A;  1I73 A;  1J7N A;  4GR8 A;  4H76 A;  1OS9 A;  3LKA A;  4GQL A;  4AYK A;  2OW1 A;  1A86 A;  1MMB A;  1G05 A;  3CKI A;  2J83 A;  1KBC A;  1BQQ M;  1CAQ A;  1JAN A;  4PKR A;  3LUN A;  1C7K A;  5CUH A;  3KMC A;  3TSK A;  1Y8J A;  5B5P A;  5LAB A;  1OM7 A;  3LIL A;  1KUF A;  1BKC A;  1CQR A;  1QIB A;  5BOY A;  3B8Z A;  3N2V A;  3KEJ A;  1I1I P;  2SRT A;  3F18 A;  4JIJ A;  1BKC I;  3BA0 A;  4R3V A;  2PJT A;  4WK7 A;  1AST A;  4IN9 A;  1G12 A;  5D1S A;  3G42 A;  2CLT A;  3VTG A;  3KRY A;  1SMP A;  4G0D A;  2W15 A;  4WF6 A;  2DW1 A;  1OM6 A;  4PKT A;  3DWB A;  3KHI A;  1ZS0 A;  1DMT A;  5D2B A;  2MLS A;  2XS4 A;  3P1V A;  4PKU A;  3WV2 A;  1BUD A;  1Z3J A;  3MA2 A;  1XUC A;  1R1J A;  3N2U A;  2AIG P;  3KME A;  2DW2 A;  4JPA A;  966C A;  3HDB A;  5L79 A;  2OY4 A;  2WO9 A;  3KWV C;  5D1U A;  4HMA A;  1XFX A;  2FV9 A;  3TS4 A;  1JJ9 A;  1JH1 A;  2J0T A;  1BQO A;  3KEC A;  1ND1 A;  4DV8 A;  2ERP A;  2OXZ A;  3Q2H A;  3HBU P;  1GE7 A;  4ON1 A;  1XUR A;  1JIZ A;  3P24 A;  4WKE A;  1IAE A;  1G49 A;  2JT5 A;  1GO8 P;  1H71 P;  1JAO A;  1BM6 A;  2TCL A;  1YOU A;  1AKL A;  1GO7 P;  4IJO A;  1D8M A;  1MNC A;  4AXQ A;  3GBO A;  1FLS A;  1SLN A;  4JQG A;  3ZXH A;  4XM6 A;  1O0T A;  2ERO A;  3SHI A;  4XBH A;  1IAB A;  2X3C A;  1RMZ A;  1K7G A;  2O36 A;  5I43 A;  2X3B A;  1S4B P;  2OY2 A;  4GR0 A;  2E3X A;  1OMJ A;  1D7X A;  5CXA A;  2JIH A;  5B5O A;  4FXY P;  4DPE A;  456C A;  1BIW A;  3EDG A;  1C3I A;  3LQ0 A;  2MLR A;  3F1A A;  4I03 A;  2CKI A;  4H3X A;  1B8Y A;  4ZR5 A;  1KAP P;  4L63 A;  4FXQ A;  1KUH A;  2OI0 A;  4WKI A;  4A7B A;  3LUM A;  4FU4 A;  4XM7 A;  1JAQ A;  5D3C A;  4I35 A;  4L6T A;  2MZI A;  1EB6 A;  2W13 A;  1A85 A;  2OW2 A;  2Y6C A;  1HTD A;  3LJZ A;  3L0V A;  3EWJ A;  2D1O A;  2KRJ A;  4CTH A;  1ZTQ A;  2V4B A;  1G9K A;  3DNG A;  2RJP A;  3HBV P;  4A3W A;  3KEK A;  3B2Z A;  4IUW A;  4H2E A;  3LIR A;  3I7I A;  4QKZ A;  1CIZ A;  1KUK A;  3LK8 A;  4H84 A;  1IAD A;  1KUG A;  5I3M A;  1K7I A;  2RJQ A;  1SRP A;  3K7L A;  4EFS A;  3TT4 A;  1IAG A;  1EUB A;  3LIK A;  2DW0 A;  1D5J A;  4AIG A;  3K7N A;  4WZV A;  3E8R A;  2OW9 A;  3EDH A;  2E2D A;  830C A;  2OXU A;  1QIC A;  3I7G A;  1ZP5 A;  1ROS A;  5CZM A;  4PKW A;  4GF1 A;  2O3E A;  3B92 A;  2JSD A;  3EDZ A;  3ZVS A;  4AUO A;  1PWW A;  1HFC A;  3HDA P;  3LJG A;  3ELM A;  2OVX A;  1ATL A;  3AYU A;  1UEA A;  5I12 A;  2JT6 A;  3EDI A;  4H1Q A;  1JAP A; 
#chains in the Genus database with same CATH topology
 4G9L A;  1QJJ A;  1OM8 A;  3OHL A;  1PWQ A;  1JK3 A;  3LJT A;  4PKS A;  3NX7 A;  2OZR A;  1SAT A;  3G5C A;  1I76 A;  3V96 B;  4L19 A;  1GKC A;  1XFZ A;  2W14 A;  3HB2 P;  1XFV A;  1Y0V A;  2K9C A;  5I0L A;  1BUV M;  1D8F A;  1CGL A;  1PWV A;  5D1T A;  1XM5 A;  2W12 A;  3RTT A;  1ZXV A;  1XUD A;  4PKV A;  1DTH A;  1HY7 A;  1CGF A;  2L0R A;  2WOA A;  2MZH A;  5L7F A;  4GUY A;  3USN A;  3TVC A;  1ZXC A;  3ZUK A;  1BZS A;  2A8H A;  4H49 A;  1YP1 A;  2WO8 A;  4H82 A;  3O2X A;  4L7A A;  4PKQ A;  3LMC A;  1PWU A;  1O0Q A;  5BOT A;  1FBL A;  2YB9 A;  4GR3 A;  2X7M A;  1GE5 A;  3EHY A;  1WNI A;  2POJ A;  2OVZ A;  4DF9 A;  1R55 A;  1UMS A;  1OS2 A;  1FM1 A;  1MMQ A;  2DDF A;  2OW0 A;  3VI1 A;  1QJI A;  2N8R A;  2OXW A;  2ERQ A;  1UTT A;  3AIG A;  3AYK A;  1RM8 A;  2FV5 A;  1Q3A A;  4JA1 A;  1R1I A;  2X3A A;  3EHX A;  5JMY A;  3LQB A;  2W0D A;  3LEA A;  2K2G A;  2QPJ A;  3F15 A;  1MMR A;  1K7Q A;  1XFY A;  4GWM A;  3UVC A;  1C8T A;  1HV5 A;  1IAC A;  3F17 A;  1G4K A;  2DDY A;  2Y6D A;  4DD8 A;  1JIW P;  2USN A;  4FVL A;  1GE6 A;  1HOV A;  1QIA A;  1GXD A;  1BKC E;  1UMT A;  2YIG A;  1AF0 A;  3HYG A;  2XS3 A;  1QUA A;  1GKD A;  4Q1L A;  1BSW A;  3F19 A;  4JP4 A;  4XCT A;  1CGE A;  4H30 A;  1YQY A;  5D7W A;  1SU3 A;  1XFW A;  3OHO A;  1Y93 A;  1KUI A;  1JKY A;  1ZVX A;  3DL1 A;  1MMP A;  2D1N A;  3O64 A;  2HU6 A;  3WV1 A;  1YCM A;  2MZE A;  3DSL A;  3F16 A;  3DPE A;  3L0T A;  1R54 A;  1XFU A;  1OO9 A;  5H8X A;  3LE9 A;  1CK7 A;  4HX3 A;  2I47 A;  1L6J A;  1R1H A;  3WV3 A;  3Q2G A;  1HFS A;  4GWN A;  3HY9 A;  1PWP A;  4ILW D;  1IAA A;  1AYK A;  3HY7 A;  3U1R A;  5BPA A;  4XM8 A;  1CXV A;  1EAK A;  3DPF A;  4J4M A;  2JNP A;  3LGP A;  5I4O A;  2Z2D A;  1USN A;  1B3D A;  5I2Z A;  1SLM A;  2AYK A;  1UTZ A;  3RTS A;  1I73 A;  1J7N A;  4GR8 A;  4H76 A;  1OS9 A;  3LKA A;  4GQL A;  4AYK A;  2OW1 A;  1A86 A;  1MMB A;  1G05 A;  3CKI A;  2J83 A;  1KBC A;  1BQQ M;  1CAQ A;  1JAN A;  4PKR A;  3LUN A;  1C7K A;  5CUH A;  3KMC A;  3TSK A;  1Y8J A;  5B5P A;  5LAB A;  1OM7 A;  3LIL A;  1KUF A;  1BKC A;  1CQR A;  1QIB A;  5BOY A;  3B8Z A;  3N2V A;  3KEJ A;  1I1I P;  2SRT A;  3F18 A;  4JIJ A;  1BKC I;  3BA0 A;  4R3V A;  2PJT A;  4WK7 A;  1AST A;  4IN9 A;  1G12 A;  5D1S A;  3G42 A;  2CLT A;  3VTG A;  3DTI A;  3KRY A;  1SMP A;  4G0D A;  2W15 A;  4WF6 A;  2DW1 A;  1OM6 A;  4PKT A;  3DWB A;  3KHI A;  1ZS0 A;  1DMT A;  5D2B A;  2MLS A;  2XS4 A;  3P1V A;  4PKU A;  3WV2 A;  1BUD A;  1Z3J A;  3MA2 A;  1XUC A;  1R1J A;  3N2U A;  2AIG P;  3KME A;  2DW2 A;  4JPA A;  966C A;  3HDB A;  5L79 A;  2OY4 A;  2WO9 A;  3KWV C;  5D1U A;  3DTK A;  4HMA A;  1XFX A;  2FV9 A;  3TS4 A;  1JJ9 A;  1JH1 A;  2J0T A;  1BQO A;  3KEC A;  1ND1 A;  4DV8 A;  2ERP A;  2OXZ A;  1TVI A;  3Q2H A;  3HBU P;  1GE7 A;  4ON1 A;  1XUR A;  1JIZ A;  3P24 A;  4WKE A;  1IAE A;  1G49 A;  2JT5 A;  1GO8 P;  1H71 P;  1JAO A;  1BM6 A;  2TCL A;  1YOU A;  1AKL A;  1GO7 P;  4IJO A;  1D8M A;  1MNC A;  4AXQ A;  3GBO A;  1FLS A;  1SLN A;  4JQG A;  3ZXH A;  4XM6 A;  1O0T A;  2ERO A;  3SHI A;  4XBH A;  1IAB A;  2X3C A;  1RMZ A;  1K7G A;  2O36 A;  5I43 A;  2X3B A;  1S4B P;  2OY2 A;  4GR0 A;  2E3X A;  1OMJ A;  1D7X A;  5CXA A;  2JIH A;  5B5O A;  4FXY P;  4DPE A;  456C A;  1BIW A;  3EDG A;  1C3I A;  3LQ0 A;  2MLR A;  3F1A A;  4I03 A;  2YUF A;  2CKI A;  4H3X A;  1B8Y A;  1OZ9 A;  4ZR5 A;  1KAP P;  4L63 A;  4FXQ A;  1KUH A;  2OI0 A;  4WKI A;  4A7B A;  3LUM A;  4FU4 A;  4XM7 A;  1JAQ A;  5D3C A;  4I35 A;  4L6T A;  2MZI A;  1EB6 A;  2W13 A;  1A85 A;  2OW2 A;  2Y6C A;  1HTD A;  3LJZ A;  3L0V A;  3EWJ A;  2D1O A;  2KRJ A;  4CTH A;  1ZTQ A;  2V4B A;  1G9K A;  3DNG A;  2RJP A;  3HBV P;  4A3W A;  3KEK A;  3B2Z A;  4IUW A;  4H2E A;  3LIR A;  3I7I A;  4QKZ A;  1CIZ A;  1KUK A;  3LK8 A;  4H84 A;  1IAD A;  1KUG A;  5I3M A;  1K7I A;  2RJQ A;  1SRP A;  3K7L A;  4EFS A;  3TT4 A;  1IAG A;  1EUB A;  3LIK A;  2DW0 A;  1D5J A;  4AIG A;  3K7N A;  4WZV A;  3E8R A;  2OW9 A;  3EDH A;  2E2D A;  1XAX A;  830C A;  2OXU A;  1QIC A;  3I7G A;  1ZP5 A;  1ROS A;  5CZM A;  4PKW A;  4GF1 A;  3DTE A;  2O3E A;  3B92 A;  2JSD A;  3EDZ A;  3ZVS A;  4AUO A;  1PWW A;  1HFC A;  3HDA P;  3LJG A;  3ELM A;  2OVX A;  1ATL A;  3AYU A;  1UEA A;  5I12 A;  2JT6 A;  3EDI A;  4H1Q A;  1JAP A; 
#chains in the Genus database with same CATH homology
 4G9L A;  1QJJ A;  1OM8 A;  3OHL A;  1PWQ A;  1JK3 A;  3LJT A;  4PKS A;  3NX7 A;  2OZR A;  1SAT A;  3G5C A;  1I76 A;  3V96 B;  4L19 A;  1GKC A;  1XFZ A;  2W14 A;  3HB2 P;  1XFV A;  1Y0V A;  2K9C A;  5I0L A;  1BUV M;  1D8F A;  1CGL A;  1PWV A;  5D1T A;  2W12 A;  3RTT A;  1ZXV A;  1XUD A;  4PKV A;  1DTH A;  1HY7 A;  1CGF A;  2L0R A;  2WOA A;  2MZH A;  5L7F A;  4GUY A;  3USN A;  3TVC A;  1ZXC A;  3ZUK A;  1BZS A;  2A8H A;  4H49 A;  1YP1 A;  2WO8 A;  4H82 A;  3O2X A;  4L7A A;  4PKQ A;  3LMC A;  1PWU A;  1O0Q A;  5BOT A;  1FBL A;  2YB9 A;  4GR3 A;  2X7M A;  1GE5 A;  3EHY A;  1WNI A;  2POJ A;  2OVZ A;  4DF9 A;  1R55 A;  1UMS A;  1OS2 A;  1FM1 A;  1MMQ A;  2DDF A;  2OW0 A;  3VI1 A;  1QJI A;  2N8R A;  2OXW A;  2ERQ A;  1UTT A;  3AIG A;  3AYK A;  1RM8 A;  2FV5 A;  1Q3A A;  4JA1 A;  1R1I A;  2X3A A;  3EHX A;  5JMY A;  3LQB A;  2W0D A;  3LEA A;  2K2G A;  2QPJ A;  3F15 A;  1MMR A;  1K7Q A;  1XFY A;  4GWM A;  3UVC A;  1C8T A;  1HV5 A;  1IAC A;  3F17 A;  1G4K A;  2DDY A;  2Y6D A;  4DD8 A;  1JIW P;  2USN A;  4FVL A;  1GE6 A;  1HOV A;  1QIA A;  1GXD A;  1BKC E;  1UMT A;  2YIG A;  1AF0 A;  3HYG A;  2XS3 A;  1QUA A;  1GKD A;  4Q1L A;  1BSW A;  3F19 A;  4JP4 A;  4XCT A;  1CGE A;  4H30 A;  1YQY A;  5D7W A;  1SU3 A;  1XFW A;  3OHO A;  1Y93 A;  1KUI A;  1JKY A;  1ZVX A;  3DL1 A;  1MMP A;  2D1N A;  3O64 A;  2HU6 A;  3WV1 A;  1YCM A;  2MZE A;  3DSL A;  3F16 A;  3DPE A;  3L0T A;  1R54 A;  1XFU A;  1OO9 A;  5H8X A;  3LE9 A;  1CK7 A;  4HX3 A;  2I47 A;  1L6J A;  1R1H A;  3WV3 A;  3Q2G A;  1HFS A;  4GWN A;  3HY9 A;  1PWP A;  4ILW D;  1IAA A;  1AYK A;  3HY7 A;  3U1R A;  5BPA A;  4XM8 A;  1CXV A;  1EAK A;  3DPF A;  4J4M A;  2JNP A;  3LGP A;  5I4O A;  2Z2D A;  1USN A;  1B3D A;  5I2Z A;  1SLM A;  2AYK A;  1UTZ A;  3RTS A;  1I73 A;  1J7N A;  4GR8 A;  4H76 A;  1OS9 A;  3LKA A;  4GQL A;  4AYK A;  2OW1 A;  1A86 A;  1MMB A;  1G05 A;  3CKI A;  2J83 A;  1KBC A;  1BQQ M;  1CAQ A;  1JAN A;  4PKR A;  3LUN A;  1C7K A;  5CUH A;  3KMC A;  3TSK A;  1Y8J A;  5B5P A;  5LAB A;  1OM7 A;  3LIL A;  1KUF A;  1BKC A;  1CQR A;  1QIB A;  5BOY A;  3B8Z A;  3N2V A;  3KEJ A;  1I1I P;  2SRT A;  3F18 A;  4JIJ A;  1BKC I;  3BA0 A;  4R3V A;  2PJT A;  4WK7 A;  1AST A;  4IN9 A;  1G12 A;  5D1S A;  3G42 A;  2CLT A;  3VTG A;  3DTI A;  3KRY A;  1SMP A;  4G0D A;  2W15 A;  4WF6 A;  2DW1 A;  1OM6 A;  4PKT A;  3DWB A;  3KHI A;  1ZS0 A;  1DMT A;  5D2B A;  2MLS A;  2XS4 A;  3P1V A;  4PKU A;  3WV2 A;  1BUD A;  1Z3J A;  3MA2 A;  1XUC A;  1R1J A;  3N2U A;  2AIG P;  3KME A;  2DW2 A;  4JPA A;  966C A;  3HDB A;  5L79 A;  2OY4 A;  2WO9 A;  3KWV C;  5D1U A;  3DTK A;  4HMA A;  1XFX A;  2FV9 A;  3TS4 A;  1JJ9 A;  1JH1 A;  2J0T A;  1BQO A;  3KEC A;  1ND1 A;  4DV8 A;  2ERP A;  2OXZ A;  3Q2H A;  3HBU P;  1GE7 A;  4ON1 A;  1XUR A;  1JIZ A;  3P24 A;  4WKE A;  1IAE A;  1G49 A;  2JT5 A;  1GO8 P;  1H71 P;  1JAO A;  1BM6 A;  2TCL A;  1YOU A;  1AKL A;  1GO7 P;  4IJO A;  1D8M A;  1MNC A;  4AXQ A;  3GBO A;  1FLS A;  1SLN A;  4JQG A;  3ZXH A;  4XM6 A;  1O0T A;  2ERO A;  3SHI A;  4XBH A;  1IAB A;  2X3C A;  1RMZ A;  1K7G A;  2O36 A;  5I43 A;  2X3B A;  1S4B P;  2OY2 A;  4GR0 A;  2E3X A;  1OMJ A;  1D7X A;  5CXA A;  2JIH A;  5B5O A;  4FXY P;  4DPE A;  456C A;  1BIW A;  3EDG A;  1C3I A;  3LQ0 A;  2MLR A;  3F1A A;  4I03 A;  2YUF A;  2CKI A;  4H3X A;  1B8Y A;  4ZR5 A;  1KAP P;  4L63 A;  4FXQ A;  1KUH A;  2OI0 A;  4WKI A;  4A7B A;  3LUM A;  4FU4 A;  4XM7 A;  1JAQ A;  5D3C A;  4I35 A;  4L6T A;  2MZI A;  1EB6 A;  2W13 A;  1A85 A;  2OW2 A;  2Y6C A;  1HTD A;  3LJZ A;  3L0V A;  3EWJ A;  2D1O A;  2KRJ A;  4CTH A;  1ZTQ A;  2V4B A;  1G9K A;  3DNG A;  2RJP A;  3HBV P;  4A3W A;  3KEK A;  3B2Z A;  4IUW A;  4H2E A;  3LIR A;  3I7I A;  4QKZ A;  1CIZ A;  1KUK A;  3LK8 A;  4H84 A;  1IAD A;  1KUG A;  5I3M A;  1K7I A;  2RJQ A;  1SRP A;  3K7L A;  4EFS A;  3TT4 A;  1IAG A;  1EUB A;  3LIK A;  2DW0 A;  1D5J A;  4AIG A;  3K7N A;  4WZV A;  3E8R A;  2OW9 A;  3EDH A;  2E2D A;  830C A;  2OXU A;  1QIC A;  3I7G A;  1ZP5 A;  1ROS A;  5CZM A;  4PKW A;  4GF1 A;  3DTE A;  2O3E A;  3B92 A;  2JSD A;  3EDZ A;  3ZVS A;  4AUO A;  1PWW A;  1HFC A;  3HDA P;  3LJG A;  3ELM A;  2OVX A;  1ATL A;  3AYU A;  1UEA A;  5I12 A;  2JT6 A;  3EDI A;  4H1Q A;  1JAP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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