1ZXCA

Crystal structure of catalytic domain of tnf-alpha converting enzyme (tace) with inhibitor
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
259
structure length
259
Chain Sequence
DPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERSN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Acetylenic TACE inhibitors. Part 2: SAR of six-membered cyclic sulfonamide hydroxamates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ADAM 17
total genus 87
structure length 259
sequence length 259
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2005-06-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1zxcA00
5BOYA 3DSLA 3HB2P 1XFUA 2OXZA 1QJJA 1PWUA 1KBCA 3SHIA 4ZR5A 1ZP5A 1YP1A 1YQYA 1IABA 3OHOA 1G05A 1EUBA 1H71P 1YCMA 3O2XA 1IACA 4FVLA 1XUCA 5CZMA 1R1HA 4IN9A 1MMBA 2V4BA 2MZIA 2JT5A 3LQ0A 1BM6A 2A8HA 1OM6A 2PJTA 3LUNA 1PWQA 2O3EA 3TSKA 2MZHA 4L19A 4AIGA 1ZTQA 3LQBA 3ZUKA 3B8ZA 4GR8A 4ON1A 3DNGA 2K2GA 1AF0A 3B92A 1BQQM 1UTZA 3K7NA 4PKSA 2Y6DA 3DWBA 2ERPA 2L0RA 1Z3JA 3GBOA 1D7XA 3KEKA 3V96B 2RJQA 2RJPA 4H30A 3KEJA 1GKDA 2OW1A 3EDGA 1BUDA 2POJA 1EAKA 4I35A 3KMCA 1BKCE 3P1VA 4HMAA 1QJIA 4XM6A 2FV9A 4R3VA 1GE7A 4L6TA 4WKIA 1D5JA 1XUDA 2E2DA 2OXWA 2W0DA 2J0TA 3LUMA 1PWVA 1JJ9A 1XURA 2DDFA 1ASTA 1IAAA 1WNIA 1JAQA 4JQGA 1JIZA 3ZVSA 1CGEA 3HYGA 5D1TA 1OM8A 1UMSA 4H76A 1JKYA 1RM8A 2AIGP 2KRJA 3LMCA 2XS3A 1UMTA 2TCLA 3AYKA 4XCTA 1XFVA 4FXQA 1CIZA 3WV2A 2QPJA 4GQLA 4H3XA 3AYUA 3HBVP 5L79A 5D1UA 4AYKA 3KWVC 1B8YA 3O64A 1OMJA 1R54A 1SATA 3KMEA 3OHLA 1I76A 1J7NA 1XFYA 1HFSA 2CKIA 3F18A 3USNA 3MA2A 3LILA 5L7FA 3F19A 1AKLA 3KRYA 2OY4A 2WOAA 1R55A 4H2EA 4G9LA 3RTTA 2E3XA 1B3DA 4JIJA 1GE6A 1KUHA 1JIWP 1QICA 2OVXA 3F1AA 1CXVA 3F15A 1CQRA 1ROSA 1ATLA 2OVZA 3HY9A 3LEAA 1D8MA 4GWMA 1HV5A 2SRTA 2YIGA 4IJOA 3TT4A 1BKCA 1UTTA 4GF1A 3WV1A 5I3MA 1L6JA 3I7GA 4A7BA 3Q2HA 1BIWA 2OW9A 3I7IA 4L63A 2JSDA 1IAGA 3VTGA 1CGLA 1SMPA 3LJZA 1K7GA 3P24A 4H82A 5D2BA 5H8XA 1BSWA 2MZEA 4PKWA 1CGFA 1SLNA 4CTHA 1CK7A 1HFCA 1KUKA 2OW0A 4GUYA 1C3IA 1JAOA 4FXYP 2I47A 3TS4A 2D1OA 5LABA 3WV3A 1FM1A 1KUGA 1ZXCA 2JT6A 2OW2A 4PKVA 3F16A 1JH1A 4H84A 4AXQA 2DW2A 1I73A 4JPAA 4XBHA 3HY7A 2USNA 3LK8A 1OS2A 456CA 4G0DA 1HOVA 1Y8JA 2X3BA 4XM7A 2DW1A 1G12A 1A86A 5I4OA 2X7MA 1D8FA 1HY7A 1QUAA 1EB6A 1BKCI 3EDIA 3G5CA 830CA 1PWPA 5BPAA 5I12A 1MMPA 4DV8A 1IAEA 2HU6A 1JANA 1XFWA 1Y0VA 3TVCA 4QKZA 1ZVXA 4A3WA 4I03A 3CKIA 1UEAA 966CA 2WO9A 2DW0A 1FBLA 1OS9A 1JK3A 1Y93A 1HTDA 2XS4A 3DL1A 4HX3A 3L0VA 1BZSA 4GR0A 3LJTA 2OXUA 3L0TA 1SRPA 5JMYA 2ERQA 4GWNA 2K9CA 1DTHA 1R1JA 3DPFA 2FV5A 1A85A 2X3CA 3ZXHA 3N2UA 1MMRA 3N2VA 3UVCA 1G49A 4ILWD 5D7WA 3NX7A 3HDBA 1C8TA 1O0QA 3KECA 4PKQA 1G9KA 1QIAA 1GKCA 3EDZA 3LGPA 2EROA 3LKAA 5D1SA 2MLSA 4JA1A 1OO9A 4WK7A 3G42A 1SU3A 2W14A 2Y6CA 3LE9A 4FU4A 5CXAA 2AYKA 1IADA 3E8RA 4DF9A 4Q1LA 4J4MA 2Z2DA 1AYKA 1O0TA 3LJGA 4WF6A 3EWJA 5I2ZA 2W12A 2O36A 2W15A 2JIHA 2OY2A 3KHIA 3ELMA 1MMQA 4PKUA 2OI0A 1MNCA 1GXDA 2MLRA 1BUVM 1KAPP 1GO7P 1GO8P 3HBUP 1CAQA 3EHYA 1DMTA 2CLTA 2YB9A 1JAPA 3B2ZA 1K7QA 4DPEA 2WO8A 5B5PA 3AIGA 1RMZA 2X3AA 4GR3A 4IUWA 4DD8A 1C7KA 3BA0A 1YOUA 1BQOA 5CUHA 1USNA 4XM8A 1GE5A 2D1NA 1XFXA 1ZXVA 1I1IP 4H49A 1QIBA 1R1IA 1OM7A 5D3CA 3LIKA 4H1QA 4PKRA 3U1RA 1XFZA 4AUOA 4JP4A 4WKEA 2J83A 1ND1A 3DPEA 3K7LA 2OZRA 3VI1A 1KUFA 3EDHA 2N8RA 1ZS0A 3Q2GA 1Q3AA 3RTSA 3HDAP 1PWWA 3LIRA 1FLSA 5B5OA 3EHXA 4WZVA 3F17A 4EFSA 1S4BP 4PKTA 2W13A 1SLMA 2DDYA 5I43A 1G4KA 5BOTA 5I0LA 1KUIA 2JNPA 1K7IA
chains in the Genus database with same CATH superfamily
5BOYA 3DSLA 3HB2P 1XFUA 2OXZA 1QJJA 1PWUA 1KBCA 3SHIA 4ZR5A 1ZP5A 1YP1A 1YQYA 1IABA 3OHOA 1G05A 1EUBA 1H71P 1YCMA 3O2XA 1IACA 3DTIA 4FVLA 1XUCA 5CZMA 1R1HA 4IN9A 1MMBA 2V4BA 2MZIA 2JT5A 3LQ0A 1BM6A 2A8HA 1OM6A 2PJTA 3LUNA 1PWQA 2O3EA 3TSKA 2MZHA 4L19A 4AIGA 1ZTQA 3LQBA 3ZUKA 3B8ZA 4GR8A 4ON1A 3DNGA 2K2GA 1AF0A 3B92A 1BQQM 1UTZA 3K7NA 4PKSA 2Y6DA 3DWBA 2ERPA 2L0RA 1Z3JA 3GBOA 1D7XA 3KEKA 3V96B 2RJQA 2RJPA 4H30A 3KEJA 1GKDA 2OW1A 3EDGA 1BUDA 2POJA 1EAKA 4I35A 3KMCA 1BKCE 3P1VA 4HMAA 1QJIA 4XM6A 2FV9A 4R3VA 1GE7A 4L6TA 4WKIA 1D5JA 1XUDA 2E2DA 2OXWA 2W0DA 2J0TA 3LUMA 1PWVA 1JJ9A 1XURA 2DDFA 3DTEA 1ASTA 1IAAA 1WNIA 1JAQA 4JQGA 1JIZA 3ZVSA 1CGEA 3HYGA 5D1TA 1OM8A 1UMSA 4H76A 1JKYA 1RM8A 2AIGP 2KRJA 3LMCA 2XS3A 1UMTA 1OZ9A 2TCLA 3AYKA 4XCTA 1XFVA 4FXQA 1CIZA 3WV2A 2QPJA 4GQLA 4H3XA 3AYUA 3HBVP 5L79A 5D1UA 4AYKA 3KWVC 1B8YA 3O64A 1OMJA 1R54A 1SATA 3KMEA 3OHLA 1I76A 1J7NA 1XFYA 1HFSA 2CKIA 3F18A 3USNA 3MA2A 3LILA 5L7FA 3F19A 1AKLA 3KRYA 2OY4A 2WOAA 1R55A 4H2EA 4G9LA 3RTTA 2E3XA 1B3DA 4JIJA 1GE6A 1KUHA 1JIWP 1QICA 2OVXA 3F1AA 1CXVA 3F15A 1CQRA 1ROSA 1ATLA 2OVZA 3HY9A 4L7AA 3LEAA 1D8MA 4GWMA 1HV5A 2SRTA 2YIGA 4IJOA 3TT4A 1BKCA 1UTTA 4GF1A 3WV1A 5I3MA 1L6JA 3I7GA 4A7BA 3Q2HA 1BIWA 2OW9A 3I7IA 4L63A 2JSDA 1IAGA 3VTGA 1CGLA 1SMPA 3LJZA 1K7GA 3P24A 4H82A 5D2BA 5H8XA 1BSWA 2MZEA 4PKWA 1CGFA 1SLNA 1XAXA 4CTHA 1CK7A 1HFCA 1KUKA 2OW0A 4GUYA 1C3IA 1JAOA 4FXYP 2I47A 3TS4A 2D1OA 5LABA 3WV3A 1FM1A 1KUGA 1ZXCA 2JT6A 2OW2A 4PKVA 3F16A 1JH1A 4H84A 4AXQA 2DW2A 1I73A 4JPAA 4XBHA 3HY7A 2USNA 3LK8A 1OS2A 456CA 4G0DA 1HOVA 1Y8JA 2X3BA 4XM7A 2DW1A 1G12A 1A86A 5I4OA 2X7MA 1D8FA 1HY7A 1QUAA 1EB6A 1BKCI 3EDIA 3G5CA 830CA 1PWPA 5BPAA 5I12A 1MMPA 4DV8A 1IAEA 2HU6A 1JANA 1XFWA 1Y0VA 3TVCA 4QKZA 1ZVXA 4A3WA 4I03A 3CKIA 1UEAA 966CA 2WO9A 2DW0A 1FBLA 1OS9A 1JK3A 1Y93A 1HTDA 2XS4A 3DL1A 4HX3A 3L0VA 1BZSA 4GR0A 3LJTA 2OXUA 3L0TA 1SRPA 5JMYA 2ERQA 4GWNA 2K9CA 1DTHA 1R1JA 3DPFA 2FV5A 1A85A 2X3CA 3ZXHA 3N2UA 1MMRA 3N2VA 3UVCA 1G49A 4ILWD 5D7WA 3NX7A 3HDBA 1C8TA 1O0QA 3KECA 4PKQA 1G9KA 1QIAA 1GKCA 3EDZA 3LGPA 2EROA 3LKAA 5D1SA 2MLSA 4JA1A 1OO9A 4WK7A 3G42A 1SU3A 2W14A 2Y6CA 3LE9A 4FU4A 5CXAA 2AYKA 1IADA 1XM5A 3E8RA 4DF9A 4Q1LA 4J4MA 2Z2DA 1AYKA 1O0TA 3LJGA 4WF6A 3EWJA 5I2ZA 2W12A 2O36A 2W15A 2JIHA 2OY2A 3KHIA 3ELMA 1MMQA 4PKUA 2OI0A 1MNCA 1GXDA 2MLRA 1BUVM 1KAPP 1GO7P 1GO8P 3HBUP 1CAQA 3EHYA 1DMTA 2CLTA 2YB9A 1JAPA 3B2ZA 1K7QA 4DPEA 2WO8A 5B5PA 3AIGA 1RMZA 2X3AA 4GR3A 4IUWA 4DD8A 1C7KA 3BA0A 1YOUA 1BQOA 1TVIA 5CUHA 1USNA 4XM8A 1GE5A 2D1NA 1XFXA 1ZXVA 1I1IP 4H49A 1QIBA 1R1IA 1OM7A 5D3CA 3LIKA 4H1QA 3DTKA 4PKRA 3U1RA 1XFZA 4AUOA 4JP4A 4WKEA 2J83A 1ND1A 3DPEA 3K7LA 2OZRA 3VI1A 1KUFA 3EDHA 2N8RA 1ZS0A 3Q2GA 1Q3AA 3RTSA 3HDAP 1PWWA 3LIRA 1FLSA 5B5OA 3EHXA 4WZVA 3F17A 4EFSA 2YUFA 1S4BP 4PKTA 2W13A 1SLMA 2DDYA 5I43A 1G4KA 5BOTA 5I0LA 1KUIA 2JNPA 1K7IA
chains in the Genus database with same CATH topology
5BOYA 3DSLA 3HB2P 1XFUA 2OXZA 1QJJA 1PWUA 1KBCA 3SHIA 4ZR5A 1ZP5A 1YP1A 1YQYA 1IABA 3OHOA 1G05A 1EUBA 1H71P 1YCMA 3O2XA 1IACA 3DTIA 4FVLA 1XUCA 5CZMA 1R1HA 4IN9A 1MMBA 2V4BA 2MZIA 2JT5A 3LQ0A 1BM6A 2A8HA 1OM6A 2PJTA 3LUNA 1PWQA 2O3EA 3TSKA 2MZHA 4L19A 4AIGA 1ZTQA 3LQBA 3ZUKA 3B8ZA 4GR8A 4ON1A 3DNGA 2K2GA 1AF0A 3B92A 1BQQM 1UTZA 3K7NA 4PKSA 2Y6DA 3DWBA 2ERPA 2L0RA 1Z3JA 3GBOA 1D7XA 3KEKA 3V96B 2RJQA 2RJPA 4H30A 3KEJA 1GKDA 2OW1A 3EDGA 1BUDA 2POJA 1EAKA 4I35A 3KMCA 1BKCE 3P1VA 4HMAA 1QJIA 4XM6A 2FV9A 4R3VA 1GE7A 4L6TA 4WKIA 1D5JA 1XUDA 2E2DA 2OXWA 2W0DA 2J0TA 3LUMA 1PWVA 1JJ9A 1XURA 2DDFA 3DTEA 1ASTA 1IAAA 1WNIA 1JAQA 4JQGA 1JIZA 3ZVSA 1CGEA 3HYGA 5D1TA 1OM8A 1UMSA 4H76A 1JKYA 1RM8A 2AIGP 2KRJA 3LMCA 2XS3A 1UMTA 2TCLA 3AYKA 4XCTA 1XFVA 4FXQA 1CIZA 3WV2A 2QPJA 4GQLA 4H3XA 3AYUA 3HBVP 5L79A 5D1UA 4AYKA 3KWVC 1B8YA 3O64A 1OMJA 1R54A 1SATA 3KMEA 3OHLA 1I76A 1J7NA 1XFYA 1HFSA 2CKIA 3F18A 3USNA 3MA2A 3LILA 5L7FA 3F19A 1AKLA 3KRYA 2OY4A 2WOAA 1R55A 4H2EA 4G9LA 3RTTA 2E3XA 1B3DA 4JIJA 1GE6A 1KUHA 1JIWP 1QICA 2OVXA 3F1AA 1CXVA 3F15A 1CQRA 1ROSA 1ATLA 2OVZA 3HY9A 4L7AA 3LEAA 1D8MA 4GWMA 1HV5A 2SRTA 2YIGA 4IJOA 3TT4A 1BKCA 1UTTA 4GF1A 3WV1A 5I3MA 1L6JA 3I7GA 4A7BA 3Q2HA 1BIWA 2OW9A 3I7IA 4L63A 2JSDA 1IAGA 3VTGA 1CGLA 1SMPA 3LJZA 1K7GA 3P24A 4H82A 5D2BA 5H8XA 1BSWA 2MZEA 4PKWA 1CGFA 1SLNA 4CTHA 1CK7A 1HFCA 1KUKA 2OW0A 4GUYA 1C3IA 1JAOA 4FXYP 2I47A 3TS4A 2D1OA 5LABA 3WV3A 1FM1A 1KUGA 1ZXCA 2JT6A 2OW2A 4PKVA 3F16A 1JH1A 4H84A 4AXQA 2DW2A 1I73A 4JPAA 4XBHA 3HY7A 2USNA 3LK8A 1OS2A 456CA 4G0DA 1HOVA 1Y8JA 2X3BA 4XM7A 2DW1A 1G12A 1A86A 5I4OA 2X7MA 1D8FA 1HY7A 1QUAA 1EB6A 1BKCI 3EDIA 3G5CA 830CA 1PWPA 5BPAA 5I12A 1MMPA 4DV8A 1IAEA 2HU6A 1JANA 1XFWA 1Y0VA 3TVCA 4QKZA 1ZVXA 4A3WA 4I03A 3CKIA 1UEAA 966CA 2WO9A 2DW0A 1FBLA 1OS9A 1JK3A 1Y93A 1HTDA 2XS4A 3DL1A 4HX3A 3L0VA 1BZSA 4GR0A 3LJTA 2OXUA 3L0TA 1SRPA 5JMYA 2ERQA 4GWNA 2K9CA 1DTHA 1R1JA 3DPFA 2FV5A 1A85A 2X3CA 3ZXHA 3N2UA 1MMRA 3N2VA 3UVCA 1G49A 4ILWD 5D7WA 3NX7A 3HDBA 1C8TA 1O0QA 3KECA 4PKQA 1G9KA 1QIAA 1GKCA 3EDZA 3LGPA 2EROA 3LKAA 5D1SA 2MLSA 4JA1A 1OO9A 4WK7A 3G42A 1SU3A 2W14A 2Y6CA 3LE9A 4FU4A 5CXAA 2AYKA 1IADA 3E8RA 4DF9A 4Q1LA 4J4MA 2Z2DA 1AYKA 1O0TA 3LJGA 4WF6A 3EWJA 5I2ZA 2W12A 2O36A 2W15A 2JIHA 2OY2A 3KHIA 3ELMA 1MMQA 4PKUA 2OI0A 1MNCA 1GXDA 2MLRA 1BUVM 1KAPP 1GO7P 1GO8P 3HBUP 1CAQA 3EHYA 1DMTA 2CLTA 2YB9A 1JAPA 3B2ZA 1K7QA 4DPEA 2WO8A 5B5PA 3AIGA 1RMZA 2X3AA 4GR3A 4IUWA 4DD8A 1C7KA 3BA0A 1YOUA 1BQOA 5CUHA 1USNA 4XM8A 1GE5A 2D1NA 1XFXA 1ZXVA 1I1IP 4H49A 1QIBA 1R1IA 1OM7A 5D3CA 3LIKA 4H1QA 3DTKA 4PKRA 3U1RA 1XFZA 4AUOA 4JP4A 4WKEA 2J83A 1ND1A 3DPEA 3K7LA 2OZRA 3VI1A 1KUFA 3EDHA 2N8RA 1ZS0A 3Q2GA 1Q3AA 3RTSA 3HDAP 1PWWA 3LIRA 1FLSA 5B5OA 3EHXA 4WZVA 3F17A 4EFSA 2YUFA 1S4BP 4PKTA 2W13A 1SLMA 2DDYA 5I43A 1G4KA 5BOTA 5I0LA 1KUIA 2JNPA 1K7IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BOY A;  3DSL A;  3HB2 P;  1XFU A;  2OXZ A;  1QJJ A;  1PWU A;  1KBC A;  3SHI A;  4ZR5 A;  1ZP5 A;  1YP1 A;  1YQY A;  1IAB A;  3OHO A;  1G05 A;  1EUB A;  1H71 P;  1YCM A;  3O2X A;  1IAC A;  4FVL A;  1XUC A;  5CZM A;  1R1H A;  4IN9 A;  1MMB A;  2V4B A;  2MZI A;  2JT5 A;  3LQ0 A;  1BM6 A;  2A8H A;  1OM6 A;  2PJT A;  3LUN A;  1PWQ A;  2O3E A;  3TSK A;  2MZH A;  4L19 A;  4AIG A;  1ZTQ A;  3LQB A;  3ZUK A;  3B8Z A;  4GR8 A;  4ON1 A;  3DNG A;  2K2G A;  1AF0 A;  3B92 A;  1BQQ M;  1UTZ A;  3K7N A;  4PKS A;  2Y6D A;  3DWB A;  2ERP A;  2L0R A;  1Z3J A;  3GBO A;  1D7X A;  3KEK A;  3V96 B;  2RJQ A;  2RJP A;  4H30 A;  3KEJ A;  1GKD A;  2OW1 A;  3EDG A;  1BUD A;  2POJ A;  1EAK A;  4I35 A;  3KMC A;  1BKC E;  3P1V A;  4HMA A;  1QJI A;  4XM6 A;  2FV9 A;  4R3V A;  1GE7 A;  4L6T A;  4WKI A;  1D5J A;  1XUD A;  2E2D A;  2OXW A;  2W0D A;  2J0T A;  3LUM A;  1PWV A;  1JJ9 A;  1XUR A;  2DDF A;  1AST A;  1IAA A;  1WNI A;  1JAQ A;  4JQG A;  1JIZ A;  3ZVS A;  1CGE A;  3HYG A;  5D1T A;  1OM8 A;  1UMS A;  4H76 A;  1JKY A;  1RM8 A;  2AIG P;  2KRJ A;  3LMC A;  2XS3 A;  1UMT A;  2TCL A;  3AYK A;  4XCT A;  1XFV A;  4FXQ A;  1CIZ A;  3WV2 A;  2QPJ A;  4GQL A;  4H3X A;  3AYU A;  3HBV P;  5L79 A;  5D1U A;  4AYK A;  3KWV C;  1B8Y A;  3O64 A;  1OMJ A;  1R54 A;  1SAT A;  3KME A;  3OHL A;  1I76 A;  1J7N A;  1XFY A;  1HFS A;  2CKI A;  3F18 A;  3USN A;  3MA2 A;  3LIL A;  5L7F A;  3F19 A;  1AKL A;  3KRY A;  2OY4 A;  2WOA A;  1R55 A;  4H2E A;  4G9L A;  3RTT A;  2E3X A;  1B3D A;  4JIJ A;  1GE6 A;  1KUH A;  1JIW P;  1QIC A;  2OVX A;  3F1A A;  1CXV A;  3F15 A;  1CQR A;  1ROS A;  1ATL A;  2OVZ A;  3HY9 A;  3LEA A;  1D8M A;  4GWM A;  1HV5 A;  2SRT A;  2YIG A;  4IJO A;  3TT4 A;  1BKC A;  1UTT A;  4GF1 A;  3WV1 A;  5I3M A;  1L6J A;  3I7G A;  4A7B A;  3Q2H A;  1BIW A;  2OW9 A;  3I7I A;  4L63 A;  2JSD A;  1IAG A;  3VTG A;  1CGL A;  1SMP A;  3LJZ A;  1K7G A;  3P24 A;  4H82 A;  5D2B A;  5H8X A;  1BSW A;  2MZE A;  4PKW A;  1CGF A;  1SLN A;  4CTH A;  1CK7 A;  1HFC A;  1KUK A;  2OW0 A;  4GUY A;  1C3I A;  1JAO A;  4FXY P;  2I47 A;  3TS4 A;  2D1O A;  5LAB A;  3WV3 A;  1FM1 A;  1KUG A;  1ZXC A;  2JT6 A;  2OW2 A;  4PKV A;  3F16 A;  1JH1 A;  4H84 A;  4AXQ A;  2DW2 A;  1I73 A;  4JPA A;  4XBH A;  3HY7 A;  2USN A;  3LK8 A;  1OS2 A;  456C A;  4G0D A;  1HOV A;  1Y8J A;  2X3B A;  4XM7 A;  2DW1 A;  1G12 A;  1A86 A;  5I4O A;  2X7M A;  1D8F A;  1HY7 A;  1QUA A;  1EB6 A;  1BKC I;  3EDI A;  3G5C A;  830C A;  1PWP A;  5BPA A;  5I12 A;  1MMP A;  4DV8 A;  1IAE A;  2HU6 A;  1JAN A;  1XFW A;  1Y0V A;  3TVC A;  4QKZ A;  1ZVX A;  4A3W A;  4I03 A;  3CKI A;  1UEA A;  966C A;  2WO9 A;  2DW0 A;  1FBL A;  1OS9 A;  1JK3 A;  1Y93 A;  1HTD A;  2XS4 A;  3DL1 A;  4HX3 A;  3L0V A;  1BZS A;  4GR0 A;  3LJT A;  2OXU A;  3L0T A;  1SRP A;  5JMY A;  2ERQ A;  4GWN A;  2K9C A;  1DTH A;  1R1J A;  3DPF A;  2FV5 A;  1A85 A;  2X3C A;  3ZXH A;  3N2U A;  1MMR A;  3N2V A;  3UVC A;  1G49 A;  4ILW D;  5D7W A;  3NX7 A;  3HDB A;  1C8T A;  1O0Q A;  3KEC A;  4PKQ A;  1G9K A;  1QIA A;  1GKC A;  3EDZ A;  3LGP A;  2ERO A;  3LKA A;  5D1S A;  2MLS A;  4JA1 A;  1OO9 A;  4WK7 A;  3G42 A;  1SU3 A;  2W14 A;  2Y6C A;  3LE9 A;  4FU4 A;  5CXA A;  2AYK A;  1IAD A;  3E8R A;  4DF9 A;  4Q1L A;  4J4M A;  2Z2D A;  1AYK A;  1O0T A;  3LJG A;  4WF6 A;  3EWJ A;  5I2Z A;  2W12 A;  2O36 A;  2W15 A;  2JIH A;  2OY2 A;  3KHI A;  3ELM A;  1MMQ A;  4PKU A;  2OI0 A;  1MNC A;  1GXD A;  2MLR A;  1BUV M;  1KAP P;  1GO7 P;  1GO8 P;  3HBU P;  1CAQ A;  3EHY A;  1DMT A;  2CLT A;  2YB9 A;  1JAP A;  3B2Z A;  1K7Q A;  4DPE A;  2WO8 A;  5B5P A;  3AIG A;  1RMZ A;  2X3A A;  4GR3 A;  4IUW A;  4DD8 A;  1C7K A;  3BA0 A;  1YOU A;  1BQO A;  5CUH A;  1USN A;  4XM8 A;  1GE5 A;  2D1N A;  1XFX A;  1ZXV A;  1I1I P;  4H49 A;  1QIB A;  1R1I A;  1OM7 A;  5D3C A;  3LIK A;  4H1Q A;  4PKR A;  3U1R A;  1XFZ A;  4AUO A;  4JP4 A;  4WKE A;  2J83 A;  1ND1 A;  3DPE A;  3K7L A;  2OZR A;  3VI1 A;  1KUF A;  3EDH A;  2N8R A;  1ZS0 A;  3Q2G A;  1Q3A A;  3RTS A;  3HDA P;  1PWW A;  3LIR A;  1FLS A;  5B5O A;  3EHX A;  4WZV A;  3F17 A;  4EFS A;  1S4B P;  4PKT A;  2W13 A;  1SLM A;  2DDY A;  5I43 A;  1G4K A;  5BOT A;  5I0L A;  1KUI A;  2JNP A;  1K7I A; 
#chains in the Genus database with same CATH topology
 5BOY A;  3DSL A;  3HB2 P;  1XFU A;  2OXZ A;  1QJJ A;  1PWU A;  1KBC A;  3SHI A;  4ZR5 A;  1ZP5 A;  1YP1 A;  1YQY A;  1IAB A;  3OHO A;  1G05 A;  1EUB A;  1H71 P;  1YCM A;  3O2X A;  1IAC A;  3DTI A;  4FVL A;  1XUC A;  5CZM A;  1R1H A;  4IN9 A;  1MMB A;  2V4B A;  2MZI A;  2JT5 A;  3LQ0 A;  1BM6 A;  2A8H A;  1OM6 A;  2PJT A;  3LUN A;  1PWQ A;  2O3E A;  3TSK A;  2MZH A;  4L19 A;  4AIG A;  1ZTQ A;  3LQB A;  3ZUK A;  3B8Z A;  4GR8 A;  4ON1 A;  3DNG A;  2K2G A;  1AF0 A;  3B92 A;  1BQQ M;  1UTZ A;  3K7N A;  4PKS A;  2Y6D A;  3DWB A;  2ERP A;  2L0R A;  1Z3J A;  3GBO A;  1D7X A;  3KEK A;  3V96 B;  2RJQ A;  2RJP A;  4H30 A;  3KEJ A;  1GKD A;  2OW1 A;  3EDG A;  1BUD A;  2POJ A;  1EAK A;  4I35 A;  3KMC A;  1BKC E;  3P1V A;  4HMA A;  1QJI A;  4XM6 A;  2FV9 A;  4R3V A;  1GE7 A;  4L6T A;  4WKI A;  1D5J A;  1XUD A;  2E2D A;  2OXW A;  2W0D A;  2J0T A;  3LUM A;  1PWV A;  1JJ9 A;  1XUR A;  2DDF A;  3DTE A;  1AST A;  1IAA A;  1WNI A;  1JAQ A;  4JQG A;  1JIZ A;  3ZVS A;  1CGE A;  3HYG A;  5D1T A;  1OM8 A;  1UMS A;  4H76 A;  1JKY A;  1RM8 A;  2AIG P;  2KRJ A;  3LMC A;  2XS3 A;  1UMT A;  1OZ9 A;  2TCL A;  3AYK A;  4XCT A;  1XFV A;  4FXQ A;  1CIZ A;  3WV2 A;  2QPJ A;  4GQL A;  4H3X A;  3AYU A;  3HBV P;  5L79 A;  5D1U A;  4AYK A;  3KWV C;  1B8Y A;  3O64 A;  1OMJ A;  1R54 A;  1SAT A;  3KME A;  3OHL A;  1I76 A;  1J7N A;  1XFY A;  1HFS A;  2CKI A;  3F18 A;  3USN A;  3MA2 A;  3LIL A;  5L7F A;  3F19 A;  1AKL A;  3KRY A;  2OY4 A;  2WOA A;  1R55 A;  4H2E A;  4G9L A;  3RTT A;  2E3X A;  1B3D A;  4JIJ A;  1GE6 A;  1KUH A;  1JIW P;  1QIC A;  2OVX A;  3F1A A;  1CXV A;  3F15 A;  1CQR A;  1ROS A;  1ATL A;  2OVZ A;  3HY9 A;  4L7A A;  3LEA A;  1D8M A;  4GWM A;  1HV5 A;  2SRT A;  2YIG A;  4IJO A;  3TT4 A;  1BKC A;  1UTT A;  4GF1 A;  3WV1 A;  5I3M A;  1L6J A;  3I7G A;  4A7B A;  3Q2H A;  1BIW A;  2OW9 A;  3I7I A;  4L63 A;  2JSD A;  1IAG A;  3VTG A;  1CGL A;  1SMP A;  3LJZ A;  1K7G A;  3P24 A;  4H82 A;  5D2B A;  5H8X A;  1BSW A;  2MZE A;  4PKW A;  1CGF A;  1SLN A;  1XAX A;  4CTH A;  1CK7 A;  1HFC A;  1KUK A;  2OW0 A;  4GUY A;  1C3I A;  1JAO A;  4FXY P;  2I47 A;  3TS4 A;  2D1O A;  5LAB A;  3WV3 A;  1FM1 A;  1KUG A;  1ZXC A;  2JT6 A;  2OW2 A;  4PKV A;  3F16 A;  1JH1 A;  4H84 A;  4AXQ A;  2DW2 A;  1I73 A;  4JPA A;  4XBH A;  3HY7 A;  2USN A;  3LK8 A;  1OS2 A;  456C A;  4G0D A;  1HOV A;  1Y8J A;  2X3B A;  4XM7 A;  2DW1 A;  1G12 A;  1A86 A;  5I4O A;  2X7M A;  1D8F A;  1HY7 A;  1QUA A;  1EB6 A;  1BKC I;  3EDI A;  3G5C A;  830C A;  1PWP A;  5BPA A;  5I12 A;  1MMP A;  4DV8 A;  1IAE A;  2HU6 A;  1JAN A;  1XFW A;  1Y0V A;  3TVC A;  4QKZ A;  1ZVX A;  4A3W A;  4I03 A;  3CKI A;  1UEA A;  966C A;  2WO9 A;  2DW0 A;  1FBL A;  1OS9 A;  1JK3 A;  1Y93 A;  1HTD A;  2XS4 A;  3DL1 A;  4HX3 A;  3L0V A;  1BZS A;  4GR0 A;  3LJT A;  2OXU A;  3L0T A;  1SRP A;  5JMY A;  2ERQ A;  4GWN A;  2K9C A;  1DTH A;  1R1J A;  3DPF A;  2FV5 A;  1A85 A;  2X3C A;  3ZXH A;  3N2U A;  1MMR A;  3N2V A;  3UVC A;  1G49 A;  4ILW D;  5D7W A;  3NX7 A;  3HDB A;  1C8T A;  1O0Q A;  3KEC A;  4PKQ A;  1G9K A;  1QIA A;  1GKC A;  3EDZ A;  3LGP A;  2ERO A;  3LKA A;  5D1S A;  2MLS A;  4JA1 A;  1OO9 A;  4WK7 A;  3G42 A;  1SU3 A;  2W14 A;  2Y6C A;  3LE9 A;  4FU4 A;  5CXA A;  2AYK A;  1IAD A;  1XM5 A;  3E8R A;  4DF9 A;  4Q1L A;  4J4M A;  2Z2D A;  1AYK A;  1O0T A;  3LJG A;  4WF6 A;  3EWJ A;  5I2Z A;  2W12 A;  2O36 A;  2W15 A;  2JIH A;  2OY2 A;  3KHI A;  3ELM A;  1MMQ A;  4PKU A;  2OI0 A;  1MNC A;  1GXD A;  2MLR A;  1BUV M;  1KAP P;  1GO7 P;  1GO8 P;  3HBU P;  1CAQ A;  3EHY A;  1DMT A;  2CLT A;  2YB9 A;  1JAP A;  3B2Z A;  1K7Q A;  4DPE A;  2WO8 A;  5B5P A;  3AIG A;  1RMZ A;  2X3A A;  4GR3 A;  4IUW A;  4DD8 A;  1C7K A;  3BA0 A;  1YOU A;  1BQO A;  1TVI A;  5CUH A;  1USN A;  4XM8 A;  1GE5 A;  2D1N A;  1XFX A;  1ZXV A;  1I1I P;  4H49 A;  1QIB A;  1R1I A;  1OM7 A;  5D3C A;  3LIK A;  4H1Q A;  3DTK A;  4PKR A;  3U1R A;  1XFZ A;  4AUO A;  4JP4 A;  4WKE A;  2J83 A;  1ND1 A;  3DPE A;  3K7L A;  2OZR A;  3VI1 A;  1KUF A;  3EDH A;  2N8R A;  1ZS0 A;  3Q2G A;  1Q3A A;  3RTS A;  3HDA P;  1PWW A;  3LIR A;  1FLS A;  5B5O A;  3EHX A;  4WZV A;  3F17 A;  4EFS A;  2YUF A;  1S4B P;  4PKT A;  2W13 A;  1SLM A;  2DDY A;  5I43 A;  1G4K A;  5BOT A;  5I0L A;  1KUI A;  2JNP A;  1K7I A; 
#chains in the Genus database with same CATH homology
 5BOY A;  3DSL A;  3HB2 P;  1XFU A;  2OXZ A;  1QJJ A;  1PWU A;  1KBC A;  3SHI A;  4ZR5 A;  1ZP5 A;  1YP1 A;  1YQY A;  1IAB A;  3OHO A;  1G05 A;  1EUB A;  1H71 P;  1YCM A;  3O2X A;  1IAC A;  3DTI A;  4FVL A;  1XUC A;  5CZM A;  1R1H A;  4IN9 A;  1MMB A;  2V4B A;  2MZI A;  2JT5 A;  3LQ0 A;  1BM6 A;  2A8H A;  1OM6 A;  2PJT A;  3LUN A;  1PWQ A;  2O3E A;  3TSK A;  2MZH A;  4L19 A;  4AIG A;  1ZTQ A;  3LQB A;  3ZUK A;  3B8Z A;  4GR8 A;  4ON1 A;  3DNG A;  2K2G A;  1AF0 A;  3B92 A;  1BQQ M;  1UTZ A;  3K7N A;  4PKS A;  2Y6D A;  3DWB A;  2ERP A;  2L0R A;  1Z3J A;  3GBO A;  1D7X A;  3KEK A;  3V96 B;  2RJQ A;  2RJP A;  4H30 A;  3KEJ A;  1GKD A;  2OW1 A;  3EDG A;  1BUD A;  2POJ A;  1EAK A;  4I35 A;  3KMC A;  1BKC E;  3P1V A;  4HMA A;  1QJI A;  4XM6 A;  2FV9 A;  4R3V A;  1GE7 A;  4L6T A;  4WKI A;  1D5J A;  1XUD A;  2E2D A;  2OXW A;  2W0D A;  2J0T A;  3LUM A;  1PWV A;  1JJ9 A;  1XUR A;  2DDF A;  3DTE A;  1AST A;  1IAA A;  1WNI A;  1JAQ A;  4JQG A;  1JIZ A;  3ZVS A;  1CGE A;  3HYG A;  5D1T A;  1OM8 A;  1UMS A;  4H76 A;  1JKY A;  1RM8 A;  2AIG P;  2KRJ A;  3LMC A;  2XS3 A;  1UMT A;  2TCL A;  3AYK A;  4XCT A;  1XFV A;  4FXQ A;  1CIZ A;  3WV2 A;  2QPJ A;  4GQL A;  4H3X A;  3AYU A;  3HBV P;  5L79 A;  5D1U A;  4AYK A;  3KWV C;  1B8Y A;  3O64 A;  1OMJ A;  1R54 A;  1SAT A;  3KME A;  3OHL A;  1I76 A;  1J7N A;  1XFY A;  1HFS A;  2CKI A;  3F18 A;  3USN A;  3MA2 A;  3LIL A;  5L7F A;  3F19 A;  1AKL A;  3KRY A;  2OY4 A;  2WOA A;  1R55 A;  4H2E A;  4G9L A;  3RTT A;  2E3X A;  1B3D A;  4JIJ A;  1GE6 A;  1KUH A;  1JIW P;  1QIC A;  2OVX A;  3F1A A;  1CXV A;  3F15 A;  1CQR A;  1ROS A;  1ATL A;  2OVZ A;  3HY9 A;  4L7A A;  3LEA A;  1D8M A;  4GWM A;  1HV5 A;  2SRT A;  2YIG A;  4IJO A;  3TT4 A;  1BKC A;  1UTT A;  4GF1 A;  3WV1 A;  5I3M A;  1L6J A;  3I7G A;  4A7B A;  3Q2H A;  1BIW A;  2OW9 A;  3I7I A;  4L63 A;  2JSD A;  1IAG A;  3VTG A;  1CGL A;  1SMP A;  3LJZ A;  1K7G A;  3P24 A;  4H82 A;  5D2B A;  5H8X A;  1BSW A;  2MZE A;  4PKW A;  1CGF A;  1SLN A;  4CTH A;  1CK7 A;  1HFC A;  1KUK A;  2OW0 A;  4GUY A;  1C3I A;  1JAO A;  4FXY P;  2I47 A;  3TS4 A;  2D1O A;  5LAB A;  3WV3 A;  1FM1 A;  1KUG A;  1ZXC A;  2JT6 A;  2OW2 A;  4PKV A;  3F16 A;  1JH1 A;  4H84 A;  4AXQ A;  2DW2 A;  1I73 A;  4JPA A;  4XBH A;  3HY7 A;  2USN A;  3LK8 A;  1OS2 A;  456C A;  4G0D A;  1HOV A;  1Y8J A;  2X3B A;  4XM7 A;  2DW1 A;  1G12 A;  1A86 A;  5I4O A;  2X7M A;  1D8F A;  1HY7 A;  1QUA A;  1EB6 A;  1BKC I;  3EDI A;  3G5C A;  830C A;  1PWP A;  5BPA A;  5I12 A;  1MMP A;  4DV8 A;  1IAE A;  2HU6 A;  1JAN A;  1XFW A;  1Y0V A;  3TVC A;  4QKZ A;  1ZVX A;  4A3W A;  4I03 A;  3CKI A;  1UEA A;  966C A;  2WO9 A;  2DW0 A;  1FBL A;  1OS9 A;  1JK3 A;  1Y93 A;  1HTD A;  2XS4 A;  3DL1 A;  4HX3 A;  3L0V A;  1BZS A;  4GR0 A;  3LJT A;  2OXU A;  3L0T A;  1SRP A;  5JMY A;  2ERQ A;  4GWN A;  2K9C A;  1DTH A;  1R1J A;  3DPF A;  2FV5 A;  1A85 A;  2X3C A;  3ZXH A;  3N2U A;  1MMR A;  3N2V A;  3UVC A;  1G49 A;  4ILW D;  5D7W A;  3NX7 A;  3HDB A;  1C8T A;  1O0Q A;  3KEC A;  4PKQ A;  1G9K A;  1QIA A;  1GKC A;  3EDZ A;  3LGP A;  2ERO A;  3LKA A;  5D1S A;  2MLS A;  4JA1 A;  1OO9 A;  4WK7 A;  3G42 A;  1SU3 A;  2W14 A;  2Y6C A;  3LE9 A;  4FU4 A;  5CXA A;  2AYK A;  1IAD A;  3E8R A;  4DF9 A;  4Q1L A;  4J4M A;  2Z2D A;  1AYK A;  1O0T A;  3LJG A;  4WF6 A;  3EWJ A;  5I2Z A;  2W12 A;  2O36 A;  2W15 A;  2JIH A;  2OY2 A;  3KHI A;  3ELM A;  1MMQ A;  4PKU A;  2OI0 A;  1MNC A;  1GXD A;  2MLR A;  1BUV M;  1KAP P;  1GO7 P;  1GO8 P;  3HBU P;  1CAQ A;  3EHY A;  1DMT A;  2CLT A;  2YB9 A;  1JAP A;  3B2Z A;  1K7Q A;  4DPE A;  2WO8 A;  5B5P A;  3AIG A;  1RMZ A;  2X3A A;  4GR3 A;  4IUW A;  4DD8 A;  1C7K A;  3BA0 A;  1YOU A;  1BQO A;  5CUH A;  1USN A;  4XM8 A;  1GE5 A;  2D1N A;  1XFX A;  1ZXV A;  1I1I P;  4H49 A;  1QIB A;  1R1I A;  1OM7 A;  5D3C A;  3LIK A;  4H1Q A;  3DTK A;  4PKR A;  3U1R A;  1XFZ A;  4AUO A;  4JP4 A;  4WKE A;  2J83 A;  1ND1 A;  3DPE A;  3K7L A;  2OZR A;  3VI1 A;  1KUF A;  3EDH A;  2N8R A;  1ZS0 A;  3Q2G A;  1Q3A A;  3RTS A;  3HDA P;  1PWW A;  3LIR A;  1FLS A;  5B5O A;  3EHX A;  4WZV A;  3F17 A;  4EFS A;  2YUF A;  1S4B P;  4PKT A;  2W13 A;  1SLM A;  2DDY A;  5I43 A;  1G4K A;  5BOT A;  5I0L A;  1KUI A;  2JNP A;  1K7I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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