1BIWA

Design and synthesis of conformationally-constrained mmp inhibitors
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
169
structure length
169
Chain Sequence
FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and synthesis of conformationally-constrained MMP inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN (STROMELYSIN-1 COMPLEX)
total genus 46
structure length 169
sequence length 169
chains with identical sequence B
ec nomenclature ec 3.4.24.17: Stromelysin 1.
pdb deposition date 1998-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1biwA00
3LJGA 1AYKA 830CA 1EUBA 1YQYA 5I2ZA 5JMYA 3Q2HA 4H2EA 3KEJA 1G49A 1ATLA 1JANA 1XURA 1Y93A 3DL1A 1GE5A 3P24A 3O2XA 4XM7A 4JA1A 2OVXA 2Y6DA 1OS9A 1SLNA 3K7NA 1UMSA 2OY4A 2DW2A 2YIGA 1PWWA 1ROSA 1S4BP 1JAOA 3LK8A 1XFXA 2FV5A 4JP4A 1Y0VA 1QIAA 2JT5A 5L79A 4EFSA 1KUHA 1KBCA 2W15A 3ELMA 4WK7A 3U1RA 1YOUA 2K2GA 2DDFA 4H84A 2YB9A 1DTHA 1JAQA 2CKIA 2ERPA 3TVCA 3HDBA 1XUDA 2OW9A 1HV5A 3Q2GA 5BOTA 3EDGA 2X7MA 2XS4A 2TCLA 4GWMA 4AIGA 3OHOA 4Q1LA 4GR8A 2J83A 1D7XA 2JT6A 4A7BA 1XFVA 2XS3A 1XFYA 4H49A 3UVCA 1BKCE 1GXDA 1AKLA 1OMJA 4PKRA 3USNA 1ZXVA 3KEKA 3G42A 1BM6A 1FM1A 2D1OA 2PJTA 2MZIA 3LQ0A 1USNA 5CXAA 1HOVA 1G12A 1SMPA 1YCMA 3EHYA 4WF6A 2RJPA 1QJJA 4XM6A 2D1NA 2AYKA 4DD8A 2OXZA 1CK7A 1OO9A 3LUMA 1KUIA 1O0QA 4WZVA 1UTTA 3TS4A 1R55A 1B3DA 4WKEA 3HBUP 1CQRA 3N2VA 4XM8A 4G0DA 5I3MA 2FV9A 1MMPA 4AYKA 2CLTA 1GE6A 4H3XA 4DPEA 1QUAA 1XUCA 4AUOA 4GF1A 3EHXA 4L6TA 3RTSA 1YP1A 3LEAA 5CUHA 2Y6CA 3DPEA 4GQLA 1OS2A 1UMTA 5D1UA 1CGEA 3MA2A 1XFWA 4PKTA 1O0TA 4PKSA 3B2ZA 3L0TA 1H71P 3DPFA 4H76A 2K9CA 1PWUA 1GKCA 1RMZA 2OXUA 2W13A 4ILWD 3VTGA 3LMCA 4WKIA 2N8RA 1BUVM 1IAGA 1R1IA 2WO9A 3ZVSA 5I4OA 1J7NA 3AIGA 3KRYA 1B8YA 1IAEA 3E8RA 5B5PA 1JIWP 1QIBA 1JJ9A 1MMBA 1I1IP 1C3IA 1SRPA 1JKYA 1PWQA 5LABA 1WNIA 4J4MA 1OM6A 3EWJA 1IADA 4XCTA 2WO8A 3B8ZA 3HB2P 1BQOA 1JK3A 1DMTA 4PKUA 3I7IA 3LUNA 2V4BA 1K7GA 1ND1A 2OI0A 4IJOA 2EROA 3TT4A 4A3WA 2OW0A 1KUKA 5L7FA 4L19A 3TSKA 3AYKA 3DNGA 3LIKA 3VI1A 4H82A 1CXVA 2MLSA 3LKAA 3HDAP 1D8FA 3K7LA 1ZVXA 3F18A 966CA 1HY7A 3AYUA 3EDZA 1D5JA 5D3CA 3EDHA 3HY9A 4PKQA 1CAQA 4PKVA 1R1JA 2SRTA 3F15A 4H30A 5D1TA 1MMQA 1ZP5A 1BUDA 2DW0A 2HU6A 2OZRA 5I43A 1XFUA 2ERQA 1K7QA 3ZUKA 3F17A 1ZXCA 1ZS0A 4FXQA 3WV2A 3EDIA 4GWNA 4QKZA 1CGLA 4I35A 2W12A 1ZTQA 1L6JA 2W14A 3L0VA 4JQGA 3LIRA 4DF9A 1BQQM 1G05A 1PWPA 1C7KA 1EAKA 2DW1A 1CGFA 2MZEA 1I73A 1BSWA 2USNA 4I03A 1G9KA 3LE9A 1SLMA 1AF0A 3GBOA 1KAPP 4FU4A 2L0RA 4AXQA 3P1VA 3KMCA 3G5CA 4GR3A 1Q3AA 1Y8JA 1JAPA 1IAAA 2WOAA 3DWBA 3KHIA 2W0DA 1EB6A 1BKCI 1HFSA 1KUFA 1CIZA 4HMAA 5D1SA 3DSLA 1G4KA 1R1HA 3WV3A 456CA 4GR0A 1A86A 3OHLA 5H8XA 1QJIA 1RM8A 2OY2A 5D7WA 1GE7A 2JSDA 2MZHA 1IACA 1ASTA 2E3XA 5BPAA 3NX7A 2J0TA 4ON1A 4DV8A 2JIHA 4IUWA 2OW1A 1FBLA 2O3EA 2OVZA 3N2UA 3LJTA 3RTTA 1I76A 1XFZA 3HYGA 2MLRA 3SHIA 1JIZA 3WV1A 3BA0A 3LQBA 2X3BA 1C8TA 2O36A 1A85A 3B92A 1QICA 1BKCA 1R54A 2X3AA 2RJQA 4H1QA 3LGPA 1PWVA 1KUGA 1OM8A 1GO7P 1SATA 2DDYA 3V96B 3F19A 1BZSA 1MMRA 5D2BA 4L63A 1GKDA 5I12A 3HBVP 3KECA 1MNCA 2POJA 3KWVC 1BIWA 3CKIA 3F1AA 2AIGP 4HX3A 1UEAA 4JPAA 1JH1A 3I7GA 3F16A 2Z2DA 4R3VA 1SU3A 4CTHA 1HFCA 3KMEA 2X3CA 2OW2A 4IN9A 4PKWA 3O64A 5I0LA 4GUYA 4XBHA 3ZXHA 4FVLA 3LILA 1D8MA 4G9LA 1GO8P 3HY7A 3LJZA 1HTDA 5BOYA 1K7IA 2I47A 5CZMA 2OXWA 2QPJA 4FXYP 1IABA 1OM7A 4JIJA 2E2DA 5B5OA 2KRJA 2A8HA 2JNPA 1FLSA 1UTZA 1Z3JA 4ZR5A
chains in the Genus database with same CATH superfamily
3LJGA 1AYKA 830CA 1EUBA 1YQYA 5I2ZA 5JMYA 3Q2HA 4H2EA 3KEJA 1G49A 1ATLA 1JANA 1XURA 1Y93A 3DL1A 1GE5A 3P24A 3O2XA 4XM7A 4JA1A 2OVXA 2Y6DA 1OS9A 1SLNA 3K7NA 1UMSA 2OY4A 2DW2A 2YIGA 1PWWA 1ROSA 1S4BP 1JAOA 3LK8A 1XFXA 2FV5A 4JP4A 1Y0VA 1QIAA 2JT5A 2YUFA 4EFSA 5L79A 1KUHA 1KBCA 2W15A 3ELMA 4L7AA 4WK7A 3U1RA 1YOUA 2K2GA 2DDFA 4H84A 2YB9A 1DTHA 1JAQA 2CKIA 2ERPA 3TVCA 3HDBA 1XUDA 2OW9A 1HV5A 3Q2GA 5BOTA 3EDGA 2X7MA 2XS4A 2TCLA 4GWMA 4AIGA 3OHOA 4Q1LA 4GR8A 2J83A 1D7XA 2JT6A 4A7BA 1XFVA 2XS3A 1XFYA 4H49A 3UVCA 1BKCE 1GXDA 1AKLA 1OMJA 4PKRA 3USNA 1ZXVA 1XAXA 3KEKA 3G42A 1BM6A 1FM1A 2D1OA 2PJTA 2MZIA 3LQ0A 1USNA 5CXAA 1HOVA 1G12A 1SMPA 1YCMA 3EHYA 4WF6A 2RJPA 1QJJA 4XM6A 2D1NA 2AYKA 4DD8A 2OXZA 1CK7A 1OO9A 3LUMA 1KUIA 1O0QA 4WZVA 1UTTA 3TS4A 1R55A 1B3DA 4WKEA 3HBUP 1CQRA 3N2VA 4XM8A 4G0DA 5I3MA 2FV9A 1MMPA 4AYKA 2CLTA 1GE6A 4H3XA 4DPEA 1QUAA 1XUCA 4AUOA 4GF1A 3EHXA 4L6TA 3RTSA 1YP1A 3LEAA 5CUHA 2Y6CA 3DPEA 4GQLA 1OS2A 1UMTA 5D1UA 1CGEA 3MA2A 1XFWA 4PKTA 1O0TA 4PKSA 3B2ZA 3L0TA 1H71P 3DPFA 4H76A 2K9CA 1PWUA 1GKCA 1RMZA 2OXUA 2W13A 4ILWD 3VTGA 3LMCA 4WKIA 2N8RA 1BUVM 1IAGA 1R1IA 2WO9A 3ZVSA 5I4OA 1J7NA 3AIGA 3KRYA 1B8YA 1IAEA 3E8RA 5B5PA 1JIWP 1QIBA 1JJ9A 1MMBA 1I1IP 1C3IA 1SRPA 1JKYA 1PWQA 5LABA 1WNIA 4J4MA 1OM6A 3EWJA 1IADA 4XCTA 2WO8A 3B8ZA 3HB2P 1BQOA 1JK3A 1DMTA 4PKUA 1OZ9A 3I7IA 3LUNA 2V4BA 1K7GA 1ND1A 2OI0A 4IJOA 2EROA 3TT4A 4A3WA 2OW0A 1KUKA 5L7FA 4L19A 3TSKA 3AYKA 3DNGA 3LIKA 3VI1A 4H82A 1CXVA 2MLSA 3LKAA 3HDAP 1D8FA 3K7LA 1ZVXA 3F18A 966CA 1HY7A 3AYUA 3EDZA 1D5JA 5D3CA 3EDHA 3HY9A 4PKQA 1CAQA 4PKVA 3DTIA 1R1JA 2SRTA 3F15A 4H30A 5D1TA 1MMQA 1ZP5A 1BUDA 2DW0A 2HU6A 2OZRA 5I43A 1XFUA 2ERQA 1K7QA 3ZUKA 3F17A 1ZXCA 1ZS0A 4FXQA 3WV2A 3EDIA 4GWNA 4QKZA 1CGLA 4I35A 2W12A 1ZTQA 1L6JA 2W14A 3L0VA 4JQGA 3LIRA 4DF9A 1BQQM 1G05A 1PWPA 1C7KA 1EAKA 2DW1A 1CGFA 2MZEA 1I73A 1BSWA 2USNA 4I03A 1G9KA 3LE9A 1SLMA 1AF0A 3GBOA 1KAPP 4FU4A 2L0RA 4AXQA 3P1VA 3KMCA 3G5CA 4GR3A 1Q3AA 1Y8JA 1JAPA 1IAAA 2WOAA 3DWBA 3KHIA 2W0DA 1EB6A 1BKCI 1HFSA 1KUFA 1CIZA 4HMAA 5D1SA 3DSLA 1G4KA 1R1HA 3WV3A 456CA 4GR0A 1A86A 3OHLA 5H8XA 1QJIA 1RM8A 2OY2A 5D7WA 1GE7A 2JSDA 2MZHA 1IACA 1ASTA 2E3XA 5BPAA 3NX7A 2J0TA 4ON1A 4DV8A 2JIHA 4IUWA 2OW1A 1FBLA 2O3EA 2OVZA 3N2UA 3DTEA 3LJTA 3RTTA 1XM5A 1I76A 1XFZA 3HYGA 2MLRA 3SHIA 1JIZA 3WV1A 3BA0A 3LQBA 2X3BA 1C8TA 3DTKA 2O36A 1A85A 3B92A 1TVIA 1QICA 1BKCA 1R54A 2X3AA 2RJQA 4H1QA 3LGPA 1PWVA 1KUGA 1OM8A 1GO7P 1SATA 2DDYA 3V96B 3F19A 1BZSA 1MMRA 5D2BA 4L63A 1GKDA 5I12A 3HBVP 3KECA 1MNCA 2POJA 3KWVC 1BIWA 3CKIA 3F1AA 2AIGP 4HX3A 1UEAA 4JPAA 1JH1A 3I7GA 3F16A 2Z2DA 4R3VA 1SU3A 4CTHA 1HFCA 3KMEA 2X3CA 2OW2A 4IN9A 4PKWA 3O64A 5I0LA 4GUYA 4XBHA 3ZXHA 4FVLA 1D8MA 3LILA 4G9LA 1GO8P 3HY7A 3LJZA 1HTDA 5BOYA 1K7IA 2I47A 5CZMA 2OXWA 2QPJA 4FXYP 1IABA 1OM7A 4JIJA 2E2DA 5B5OA 2KRJA 2A8HA 2JNPA 1FLSA 1UTZA 1Z3JA 4ZR5A
chains in the Genus database with same CATH topology
3LJGA 1AYKA 830CA 1EUBA 1YQYA 5I2ZA 5JMYA 3Q2HA 4H2EA 3KEJA 1G49A 1ATLA 1JANA 1XURA 1Y93A 3DL1A 1GE5A 3P24A 3O2XA 4XM7A 4JA1A 2OVXA 2Y6DA 1OS9A 1SLNA 3K7NA 1UMSA 2OY4A 2DW2A 2YIGA 1PWWA 1ROSA 1S4BP 1JAOA 3LK8A 1XFXA 2FV5A 4JP4A 1Y0VA 1QIAA 2JT5A 2YUFA 4EFSA 5L79A 1KUHA 1KBCA 2W15A 3ELMA 4L7AA 4WK7A 3U1RA 1YOUA 2K2GA 2DDFA 4H84A 2YB9A 1DTHA 1JAQA 2CKIA 2ERPA 3TVCA 3HDBA 1XUDA 2OW9A 1HV5A 3Q2GA 5BOTA 3EDGA 2X7MA 2XS4A 2TCLA 4GWMA 4AIGA 3OHOA 4Q1LA 4GR8A 2J83A 1D7XA 2JT6A 4A7BA 1XFVA 2XS3A 1XFYA 4H49A 3UVCA 1BKCE 1GXDA 1AKLA 1OMJA 4PKRA 3USNA 1ZXVA 3KEKA 3G42A 1BM6A 1FM1A 2D1OA 2PJTA 2MZIA 3LQ0A 1USNA 5CXAA 1HOVA 1G12A 1SMPA 1YCMA 3EHYA 4WF6A 2RJPA 1QJJA 4XM6A 2D1NA 2AYKA 4DD8A 2OXZA 1CK7A 1OO9A 3LUMA 1KUIA 1O0QA 4WZVA 1UTTA 3TS4A 1R55A 1B3DA 4WKEA 3HBUP 1CQRA 3N2VA 4XM8A 4G0DA 5I3MA 2FV9A 1MMPA 4AYKA 2CLTA 1GE6A 4H3XA 4DPEA 1QUAA 1XUCA 4AUOA 4GF1A 3EHXA 4L6TA 3RTSA 1YP1A 3LEAA 5CUHA 2Y6CA 3DPEA 4GQLA 1OS2A 1UMTA 5D1UA 1CGEA 3MA2A 1XFWA 4PKTA 1O0TA 4PKSA 3B2ZA 3L0TA 1H71P 3DPFA 4H76A 2K9CA 1PWUA 1GKCA 1RMZA 2OXUA 2W13A 4ILWD 3VTGA 3LMCA 4WKIA 2N8RA 1BUVM 1IAGA 1R1IA 2WO9A 3ZVSA 5I4OA 1J7NA 3AIGA 3KRYA 1B8YA 1IAEA 3E8RA 5B5PA 1JIWP 1QIBA 1JJ9A 1MMBA 1I1IP 1C3IA 1SRPA 1JKYA 1PWQA 5LABA 1WNIA 4J4MA 1OM6A 3EWJA 1IADA 4XCTA 2WO8A 3B8ZA 3HB2P 1BQOA 1JK3A 1DMTA 4PKUA 3I7IA 3LUNA 2V4BA 1K7GA 1ND1A 2OI0A 4IJOA 2EROA 3TT4A 4A3WA 2OW0A 1KUKA 5L7FA 4L19A 3TSKA 3AYKA 3DNGA 3LIKA 3VI1A 4H82A 1CXVA 2MLSA 3LKAA 3HDAP 1D8FA 3K7LA 1ZVXA 3F18A 966CA 1HY7A 3AYUA 3EDZA 1D5JA 5D3CA 3EDHA 3HY9A 4PKQA 1CAQA 4PKVA 3DTIA 1R1JA 2SRTA 3F15A 4H30A 5D1TA 1MMQA 1ZP5A 1BUDA 2DW0A 2HU6A 2OZRA 5I43A 1XFUA 2ERQA 1K7QA 3ZUKA 3F17A 1ZXCA 1ZS0A 4FXQA 3WV2A 3EDIA 4GWNA 4QKZA 1CGLA 4I35A 2W12A 1ZTQA 1L6JA 2W14A 3L0VA 4JQGA 3LIRA 4DF9A 1BQQM 1G05A 1PWPA 1C7KA 1EAKA 2DW1A 1CGFA 2MZEA 1I73A 1BSWA 2USNA 4I03A 1G9KA 3LE9A 1SLMA 1AF0A 3GBOA 1KAPP 4FU4A 2L0RA 4AXQA 3P1VA 3KMCA 3G5CA 4GR3A 1Q3AA 1Y8JA 1JAPA 1IAAA 2WOAA 3DWBA 3KHIA 2W0DA 1EB6A 1BKCI 1HFSA 1KUFA 1CIZA 4HMAA 5D1SA 3DSLA 1G4KA 1R1HA 3WV3A 456CA 4GR0A 1A86A 3OHLA 5H8XA 1QJIA 1RM8A 2OY2A 5D7WA 1GE7A 2JSDA 2MZHA 1IACA 1ASTA 2E3XA 5BPAA 3NX7A 2J0TA 4ON1A 4DV8A 2JIHA 4IUWA 2OW1A 1FBLA 2O3EA 2OVZA 3N2UA 3DTEA 3LJTA 3RTTA 1I76A 1XFZA 3HYGA 2MLRA 3SHIA 1JIZA 3WV1A 3BA0A 3LQBA 2X3BA 1C8TA 3DTKA 2O36A 1A85A 3B92A 1QICA 1BKCA 1R54A 2X3AA 2RJQA 4H1QA 3LGPA 1PWVA 1KUGA 1OM8A 1GO7P 1SATA 2DDYA 3V96B 3F19A 1BZSA 1MMRA 5D2BA 4L63A 1GKDA 5I12A 3HBVP 3KECA 1MNCA 2POJA 3KWVC 1BIWA 3CKIA 3F1AA 2AIGP 4HX3A 1UEAA 4JPAA 1JH1A 3I7GA 3F16A 2Z2DA 4R3VA 1SU3A 4CTHA 1HFCA 3KMEA 2X3CA 2OW2A 4IN9A 4PKWA 3O64A 5I0LA 4GUYA 4XBHA 3ZXHA 4FVLA 3LILA 1D8MA 4G9LA 1GO8P 3HY7A 3LJZA 1HTDA 5BOYA 1K7IA 2I47A 5CZMA 2OXWA 2QPJA 4FXYP 1IABA 1OM7A 4JIJA 2E2DA 5B5OA 2KRJA 2A8HA 2JNPA 1FLSA 1UTZA 1Z3JA 4ZR5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LJG A;  1AYK A;  830C A;  1EUB A;  1YQY A;  5I2Z A;  5JMY A;  3Q2H A;  4H2E A;  3KEJ A;  1G49 A;  1ATL A;  1JAN A;  1XUR A;  1Y93 A;  3DL1 A;  1GE5 A;  3P24 A;  3O2X A;  4XM7 A;  4JA1 A;  2OVX A;  2Y6D A;  1OS9 A;  1SLN A;  3K7N A;  1UMS A;  2OY4 A;  2DW2 A;  2YIG A;  1PWW A;  1ROS A;  1S4B P;  1JAO A;  3LK8 A;  1XFX A;  2FV5 A;  4JP4 A;  1Y0V A;  1QIA A;  2JT5 A;  5L79 A;  4EFS A;  1KUH A;  1KBC A;  2W15 A;  3ELM A;  4WK7 A;  3U1R A;  1YOU A;  2K2G A;  2DDF A;  4H84 A;  2YB9 A;  1DTH A;  1JAQ A;  2CKI A;  2ERP A;  3TVC A;  3HDB A;  1XUD A;  2OW9 A;  1HV5 A;  3Q2G A;  5BOT A;  3EDG A;  2X7M A;  2XS4 A;  2TCL A;  4GWM A;  4AIG A;  3OHO A;  4Q1L A;  4GR8 A;  2J83 A;  1D7X A;  2JT6 A;  4A7B A;  1XFV A;  2XS3 A;  1XFY A;  4H49 A;  3UVC A;  1BKC E;  1GXD A;  1AKL A;  1OMJ A;  4PKR A;  3USN A;  1ZXV A;  3KEK A;  3G42 A;  1BM6 A;  1FM1 A;  2D1O A;  2PJT A;  2MZI A;  3LQ0 A;  1USN A;  5CXA A;  1HOV A;  1G12 A;  1SMP A;  1YCM A;  3EHY A;  4WF6 A;  2RJP A;  1QJJ A;  4XM6 A;  2D1N A;  2AYK A;  4DD8 A;  2OXZ A;  1CK7 A;  1OO9 A;  3LUM A;  1KUI A;  1O0Q A;  4WZV A;  1UTT A;  3TS4 A;  1R55 A;  1B3D A;  4WKE A;  3HBU P;  1CQR A;  3N2V A;  4XM8 A;  4G0D A;  5I3M A;  2FV9 A;  1MMP A;  4AYK A;  2CLT A;  1GE6 A;  4H3X A;  4DPE A;  1QUA A;  1XUC A;  4AUO A;  4GF1 A;  3EHX A;  4L6T A;  3RTS A;  1YP1 A;  3LEA A;  5CUH A;  2Y6C A;  3DPE A;  4GQL A;  1OS2 A;  1UMT A;  5D1U A;  1CGE A;  3MA2 A;  1XFW A;  4PKT A;  1O0T A;  4PKS A;  3B2Z A;  3L0T A;  1H71 P;  3DPF A;  4H76 A;  2K9C A;  1PWU A;  1GKC A;  1RMZ A;  2OXU A;  2W13 A;  4ILW D;  3VTG A;  3LMC A;  4WKI A;  2N8R A;  1BUV M;  1IAG A;  1R1I A;  2WO9 A;  3ZVS A;  5I4O A;  1J7N A;  3AIG A;  3KRY A;  1B8Y A;  1IAE A;  3E8R A;  5B5P A;  1JIW P;  1QIB A;  1JJ9 A;  1MMB A;  1I1I P;  1C3I A;  1SRP A;  1JKY A;  1PWQ A;  5LAB A;  1WNI A;  4J4M A;  1OM6 A;  3EWJ A;  1IAD A;  4XCT A;  2WO8 A;  3B8Z A;  3HB2 P;  1BQO A;  1JK3 A;  1DMT A;  4PKU A;  3I7I A;  3LUN A;  2V4B A;  1K7G A;  1ND1 A;  2OI0 A;  4IJO A;  2ERO A;  3TT4 A;  4A3W A;  2OW0 A;  1KUK A;  5L7F A;  4L19 A;  3TSK A;  3AYK A;  3DNG A;  3LIK A;  3VI1 A;  4H82 A;  1CXV A;  2MLS A;  3LKA A;  3HDA P;  1D8F A;  3K7L A;  1ZVX A;  3F18 A;  966C A;  1HY7 A;  3AYU A;  3EDZ A;  1D5J A;  5D3C A;  3EDH A;  3HY9 A;  4PKQ A;  1CAQ A;  4PKV A;  1R1J A;  2SRT A;  3F15 A;  4H30 A;  5D1T A;  1MMQ A;  1ZP5 A;  1BUD A;  2DW0 A;  2HU6 A;  2OZR A;  5I43 A;  1XFU A;  2ERQ A;  1K7Q A;  3ZUK A;  3F17 A;  1ZXC A;  1ZS0 A;  4FXQ A;  3WV2 A;  3EDI A;  4GWN A;  4QKZ A;  1CGL A;  4I35 A;  2W12 A;  1ZTQ A;  1L6J A;  2W14 A;  3L0V A;  4JQG A;  3LIR A;  4DF9 A;  1BQQ M;  1G05 A;  1PWP A;  1C7K A;  1EAK A;  2DW1 A;  1CGF A;  2MZE A;  1I73 A;  1BSW A;  2USN A;  4I03 A;  1G9K A;  3LE9 A;  1SLM A;  1AF0 A;  3GBO A;  1KAP P;  4FU4 A;  2L0R A;  4AXQ A;  3P1V A;  3KMC A;  3G5C A;  4GR3 A;  1Q3A A;  1Y8J A;  1JAP A;  1IAA A;  2WOA A;  3DWB A;  3KHI A;  2W0D A;  1EB6 A;  1BKC I;  1HFS A;  1KUF A;  1CIZ A;  4HMA A;  5D1S A;  3DSL A;  1G4K A;  1R1H A;  3WV3 A;  456C A;  4GR0 A;  1A86 A;  3OHL A;  5H8X A;  1QJI A;  1RM8 A;  2OY2 A;  5D7W A;  1GE7 A;  2JSD A;  2MZH A;  1IAC A;  1AST A;  2E3X A;  5BPA A;  3NX7 A;  2J0T A;  4ON1 A;  4DV8 A;  2JIH A;  4IUW A;  2OW1 A;  1FBL A;  2O3E A;  2OVZ A;  3N2U A;  3LJT A;  3RTT A;  1I76 A;  1XFZ A;  3HYG A;  2MLR A;  3SHI A;  1JIZ A;  3WV1 A;  3BA0 A;  3LQB A;  2X3B A;  1C8T A;  2O36 A;  1A85 A;  3B92 A;  1QIC A;  1BKC A;  1R54 A;  2X3A A;  2RJQ A;  4H1Q A;  3LGP A;  1PWV A;  1KUG A;  1OM8 A;  1GO7 P;  1SAT A;  2DDY A;  3V96 B;  3F19 A;  1BZS A;  1MMR A;  5D2B A;  4L63 A;  1GKD A;  5I12 A;  3HBV P;  3KEC A;  1MNC A;  2POJ A;  3KWV C;  1BIW A;  3CKI A;  3F1A A;  2AIG P;  4HX3 A;  1UEA A;  4JPA A;  1JH1 A;  3I7G A;  3F16 A;  2Z2D A;  4R3V A;  1SU3 A;  4CTH A;  1HFC A;  3KME A;  2X3C A;  2OW2 A;  4IN9 A;  4PKW A;  3O64 A;  5I0L A;  4GUY A;  4XBH A;  3ZXH A;  4FVL A;  3LIL A;  1D8M A;  4G9L A;  1GO8 P;  3HY7 A;  3LJZ A;  1HTD A;  5BOY A;  1K7I A;  2I47 A;  5CZM A;  2OXW A;  2QPJ A;  4FXY P;  1IAB A;  1OM7 A;  4JIJ A;  2E2D A;  5B5O A;  2KRJ A;  2A8H A;  2JNP A;  1FLS A;  1UTZ A;  1Z3J A;  4ZR5 A; 
#chains in the Genus database with same CATH topology
 3LJG A;  1AYK A;  830C A;  1EUB A;  1YQY A;  5I2Z A;  5JMY A;  3Q2H A;  4H2E A;  3KEJ A;  1G49 A;  1ATL A;  1JAN A;  1XUR A;  1Y93 A;  3DL1 A;  1GE5 A;  3P24 A;  3O2X A;  4XM7 A;  4JA1 A;  2OVX A;  2Y6D A;  1OS9 A;  1SLN A;  3K7N A;  1UMS A;  2OY4 A;  2DW2 A;  2YIG A;  1PWW A;  1ROS A;  1S4B P;  1JAO A;  3LK8 A;  1XFX A;  2FV5 A;  4JP4 A;  1Y0V A;  1QIA A;  2JT5 A;  2YUF A;  4EFS A;  5L79 A;  1KUH A;  1KBC A;  2W15 A;  3ELM A;  4L7A A;  4WK7 A;  3U1R A;  1YOU A;  2K2G A;  2DDF A;  4H84 A;  2YB9 A;  1DTH A;  1JAQ A;  2CKI A;  2ERP A;  3TVC A;  3HDB A;  1XUD A;  2OW9 A;  1HV5 A;  3Q2G A;  5BOT A;  3EDG A;  2X7M A;  2XS4 A;  2TCL A;  4GWM A;  4AIG A;  3OHO A;  4Q1L A;  4GR8 A;  2J83 A;  1D7X A;  2JT6 A;  4A7B A;  1XFV A;  2XS3 A;  1XFY A;  4H49 A;  3UVC A;  1BKC E;  1GXD A;  1AKL A;  1OMJ A;  4PKR A;  3USN A;  1ZXV A;  1XAX A;  3KEK A;  3G42 A;  1BM6 A;  1FM1 A;  2D1O A;  2PJT A;  2MZI A;  3LQ0 A;  1USN A;  5CXA A;  1HOV A;  1G12 A;  1SMP A;  1YCM A;  3EHY A;  4WF6 A;  2RJP A;  1QJJ A;  4XM6 A;  2D1N A;  2AYK A;  4DD8 A;  2OXZ A;  1CK7 A;  1OO9 A;  3LUM A;  1KUI A;  1O0Q A;  4WZV A;  1UTT A;  3TS4 A;  1R55 A;  1B3D A;  4WKE A;  3HBU P;  1CQR A;  3N2V A;  4XM8 A;  4G0D A;  5I3M A;  2FV9 A;  1MMP A;  4AYK A;  2CLT A;  1GE6 A;  4H3X A;  4DPE A;  1QUA A;  1XUC A;  4AUO A;  4GF1 A;  3EHX A;  4L6T A;  3RTS A;  1YP1 A;  3LEA A;  5CUH A;  2Y6C A;  3DPE A;  4GQL A;  1OS2 A;  1UMT A;  5D1U A;  1CGE A;  3MA2 A;  1XFW A;  4PKT A;  1O0T A;  4PKS A;  3B2Z A;  3L0T A;  1H71 P;  3DPF A;  4H76 A;  2K9C A;  1PWU A;  1GKC A;  1RMZ A;  2OXU A;  2W13 A;  4ILW D;  3VTG A;  3LMC A;  4WKI A;  2N8R A;  1BUV M;  1IAG A;  1R1I A;  2WO9 A;  3ZVS A;  5I4O A;  1J7N A;  3AIG A;  3KRY A;  1B8Y A;  1IAE A;  3E8R A;  5B5P A;  1JIW P;  1QIB A;  1JJ9 A;  1MMB A;  1I1I P;  1C3I A;  1SRP A;  1JKY A;  1PWQ A;  5LAB A;  1WNI A;  4J4M A;  1OM6 A;  3EWJ A;  1IAD A;  4XCT A;  2WO8 A;  3B8Z A;  3HB2 P;  1BQO A;  1JK3 A;  1DMT A;  4PKU A;  1OZ9 A;  3I7I A;  3LUN A;  2V4B A;  1K7G A;  1ND1 A;  2OI0 A;  4IJO A;  2ERO A;  3TT4 A;  4A3W A;  2OW0 A;  1KUK A;  5L7F A;  4L19 A;  3TSK A;  3AYK A;  3DNG A;  3LIK A;  3VI1 A;  4H82 A;  1CXV A;  2MLS A;  3LKA A;  3HDA P;  1D8F A;  3K7L A;  1ZVX A;  3F18 A;  966C A;  1HY7 A;  3AYU A;  3EDZ A;  1D5J A;  5D3C A;  3EDH A;  3HY9 A;  4PKQ A;  1CAQ A;  4PKV A;  3DTI A;  1R1J A;  2SRT A;  3F15 A;  4H30 A;  5D1T A;  1MMQ A;  1ZP5 A;  1BUD A;  2DW0 A;  2HU6 A;  2OZR A;  5I43 A;  1XFU A;  2ERQ A;  1K7Q A;  3ZUK A;  3F17 A;  1ZXC A;  1ZS0 A;  4FXQ A;  3WV2 A;  3EDI A;  4GWN A;  4QKZ A;  1CGL A;  4I35 A;  2W12 A;  1ZTQ A;  1L6J A;  2W14 A;  3L0V A;  4JQG A;  3LIR A;  4DF9 A;  1BQQ M;  1G05 A;  1PWP A;  1C7K A;  1EAK A;  2DW1 A;  1CGF A;  2MZE A;  1I73 A;  1BSW A;  2USN A;  4I03 A;  1G9K A;  3LE9 A;  1SLM A;  1AF0 A;  3GBO A;  1KAP P;  4FU4 A;  2L0R A;  4AXQ A;  3P1V A;  3KMC A;  3G5C A;  4GR3 A;  1Q3A A;  1Y8J A;  1JAP A;  1IAA A;  2WOA A;  3DWB A;  3KHI A;  2W0D A;  1EB6 A;  1BKC I;  1HFS A;  1KUF A;  1CIZ A;  4HMA A;  5D1S A;  3DSL A;  1G4K A;  1R1H A;  3WV3 A;  456C A;  4GR0 A;  1A86 A;  3OHL A;  5H8X A;  1QJI A;  1RM8 A;  2OY2 A;  5D7W A;  1GE7 A;  2JSD A;  2MZH A;  1IAC A;  1AST A;  2E3X A;  5BPA A;  3NX7 A;  2J0T A;  4ON1 A;  4DV8 A;  2JIH A;  4IUW A;  2OW1 A;  1FBL A;  2O3E A;  2OVZ A;  3N2U A;  3DTE A;  3LJT A;  3RTT A;  1XM5 A;  1I76 A;  1XFZ A;  3HYG A;  2MLR A;  3SHI A;  1JIZ A;  3WV1 A;  3BA0 A;  3LQB A;  2X3B A;  1C8T A;  3DTK A;  2O36 A;  1A85 A;  3B92 A;  1TVI A;  1QIC A;  1BKC A;  1R54 A;  2X3A A;  2RJQ A;  4H1Q A;  3LGP A;  1PWV A;  1KUG A;  1OM8 A;  1GO7 P;  1SAT A;  2DDY A;  3V96 B;  3F19 A;  1BZS A;  1MMR A;  5D2B A;  4L63 A;  1GKD A;  5I12 A;  3HBV P;  3KEC A;  1MNC A;  2POJ A;  3KWV C;  1BIW A;  3CKI A;  3F1A A;  2AIG P;  4HX3 A;  1UEA A;  4JPA A;  1JH1 A;  3I7G A;  3F16 A;  2Z2D A;  4R3V A;  1SU3 A;  4CTH A;  1HFC A;  3KME A;  2X3C A;  2OW2 A;  4IN9 A;  4PKW A;  3O64 A;  5I0L A;  4GUY A;  4XBH A;  3ZXH A;  4FVL A;  1D8M A;  3LIL A;  4G9L A;  1GO8 P;  3HY7 A;  3LJZ A;  1HTD A;  5BOY A;  1K7I A;  2I47 A;  5CZM A;  2OXW A;  2QPJ A;  4FXY P;  1IAB A;  1OM7 A;  4JIJ A;  2E2D A;  5B5O A;  2KRJ A;  2A8H A;  2JNP A;  1FLS A;  1UTZ A;  1Z3J A;  4ZR5 A; 
#chains in the Genus database with same CATH homology
 3LJG A;  1AYK A;  830C A;  1EUB A;  1YQY A;  5I2Z A;  5JMY A;  3Q2H A;  4H2E A;  3KEJ A;  1G49 A;  1ATL A;  1JAN A;  1XUR A;  1Y93 A;  3DL1 A;  1GE5 A;  3P24 A;  3O2X A;  4XM7 A;  4JA1 A;  2OVX A;  2Y6D A;  1OS9 A;  1SLN A;  3K7N A;  1UMS A;  2OY4 A;  2DW2 A;  2YIG A;  1PWW A;  1ROS A;  1S4B P;  1JAO A;  3LK8 A;  1XFX A;  2FV5 A;  4JP4 A;  1Y0V A;  1QIA A;  2JT5 A;  2YUF A;  4EFS A;  5L79 A;  1KUH A;  1KBC A;  2W15 A;  3ELM A;  4L7A A;  4WK7 A;  3U1R A;  1YOU A;  2K2G A;  2DDF A;  4H84 A;  2YB9 A;  1DTH A;  1JAQ A;  2CKI A;  2ERP A;  3TVC A;  3HDB A;  1XUD A;  2OW9 A;  1HV5 A;  3Q2G A;  5BOT A;  3EDG A;  2X7M A;  2XS4 A;  2TCL A;  4GWM A;  4AIG A;  3OHO A;  4Q1L A;  4GR8 A;  2J83 A;  1D7X A;  2JT6 A;  4A7B A;  1XFV A;  2XS3 A;  1XFY A;  4H49 A;  3UVC A;  1BKC E;  1GXD A;  1AKL A;  1OMJ A;  4PKR A;  3USN A;  1ZXV A;  3KEK A;  3G42 A;  1BM6 A;  1FM1 A;  2D1O A;  2PJT A;  2MZI A;  3LQ0 A;  1USN A;  5CXA A;  1HOV A;  1G12 A;  1SMP A;  1YCM A;  3EHY A;  4WF6 A;  2RJP A;  1QJJ A;  4XM6 A;  2D1N A;  2AYK A;  4DD8 A;  2OXZ A;  1CK7 A;  1OO9 A;  3LUM A;  1KUI A;  1O0Q A;  4WZV A;  1UTT A;  3TS4 A;  1R55 A;  1B3D A;  4WKE A;  3HBU P;  1CQR A;  3N2V A;  4XM8 A;  4G0D A;  5I3M A;  2FV9 A;  1MMP A;  4AYK A;  2CLT A;  1GE6 A;  4H3X A;  4DPE A;  1QUA A;  1XUC A;  4AUO A;  4GF1 A;  3EHX A;  4L6T A;  3RTS A;  1YP1 A;  3LEA A;  5CUH A;  2Y6C A;  3DPE A;  4GQL A;  1OS2 A;  1UMT A;  5D1U A;  1CGE A;  3MA2 A;  1XFW A;  4PKT A;  1O0T A;  4PKS A;  3B2Z A;  3L0T A;  1H71 P;  3DPF A;  4H76 A;  2K9C A;  1PWU A;  1GKC A;  1RMZ A;  2OXU A;  2W13 A;  4ILW D;  3VTG A;  3LMC A;  4WKI A;  2N8R A;  1BUV M;  1IAG A;  1R1I A;  2WO9 A;  3ZVS A;  5I4O A;  1J7N A;  3AIG A;  3KRY A;  1B8Y A;  1IAE A;  3E8R A;  5B5P A;  1JIW P;  1QIB A;  1JJ9 A;  1MMB A;  1I1I P;  1C3I A;  1SRP A;  1JKY A;  1PWQ A;  5LAB A;  1WNI A;  4J4M A;  1OM6 A;  3EWJ A;  1IAD A;  4XCT A;  2WO8 A;  3B8Z A;  3HB2 P;  1BQO A;  1JK3 A;  1DMT A;  4PKU A;  3I7I A;  3LUN A;  2V4B A;  1K7G A;  1ND1 A;  2OI0 A;  4IJO A;  2ERO A;  3TT4 A;  4A3W A;  2OW0 A;  1KUK A;  5L7F A;  4L19 A;  3TSK A;  3AYK A;  3DNG A;  3LIK A;  3VI1 A;  4H82 A;  1CXV A;  2MLS A;  3LKA A;  3HDA P;  1D8F A;  3K7L A;  1ZVX A;  3F18 A;  966C A;  1HY7 A;  3AYU A;  3EDZ A;  1D5J A;  5D3C A;  3EDH A;  3HY9 A;  4PKQ A;  1CAQ A;  4PKV A;  3DTI A;  1R1J A;  2SRT A;  3F15 A;  4H30 A;  5D1T A;  1MMQ A;  1ZP5 A;  1BUD A;  2DW0 A;  2HU6 A;  2OZR A;  5I43 A;  1XFU A;  2ERQ A;  1K7Q A;  3ZUK A;  3F17 A;  1ZXC A;  1ZS0 A;  4FXQ A;  3WV2 A;  3EDI A;  4GWN A;  4QKZ A;  1CGL A;  4I35 A;  2W12 A;  1ZTQ A;  1L6J A;  2W14 A;  3L0V A;  4JQG A;  3LIR A;  4DF9 A;  1BQQ M;  1G05 A;  1PWP A;  1C7K A;  1EAK A;  2DW1 A;  1CGF A;  2MZE A;  1I73 A;  1BSW A;  2USN A;  4I03 A;  1G9K A;  3LE9 A;  1SLM A;  1AF0 A;  3GBO A;  1KAP P;  4FU4 A;  2L0R A;  4AXQ A;  3P1V A;  3KMC A;  3G5C A;  4GR3 A;  1Q3A A;  1Y8J A;  1JAP A;  1IAA A;  2WOA A;  3DWB A;  3KHI A;  2W0D A;  1EB6 A;  1BKC I;  1HFS A;  1KUF A;  1CIZ A;  4HMA A;  5D1S A;  3DSL A;  1G4K A;  1R1H A;  3WV3 A;  456C A;  4GR0 A;  1A86 A;  3OHL A;  5H8X A;  1QJI A;  1RM8 A;  2OY2 A;  5D7W A;  1GE7 A;  2JSD A;  2MZH A;  1IAC A;  1AST A;  2E3X A;  5BPA A;  3NX7 A;  2J0T A;  4ON1 A;  4DV8 A;  2JIH A;  4IUW A;  2OW1 A;  1FBL A;  2O3E A;  2OVZ A;  3N2U A;  3DTE A;  3LJT A;  3RTT A;  1I76 A;  1XFZ A;  3HYG A;  2MLR A;  3SHI A;  1JIZ A;  3WV1 A;  3BA0 A;  3LQB A;  2X3B A;  1C8T A;  3DTK A;  2O36 A;  1A85 A;  3B92 A;  1QIC A;  1BKC A;  1R54 A;  2X3A A;  2RJQ A;  4H1Q A;  3LGP A;  1PWV A;  1KUG A;  1OM8 A;  1GO7 P;  1SAT A;  2DDY A;  3V96 B;  3F19 A;  1BZS A;  1MMR A;  5D2B A;  4L63 A;  1GKD A;  5I12 A;  3HBV P;  3KEC A;  1MNC A;  2POJ A;  3KWV C;  1BIW A;  3CKI A;  3F1A A;  2AIG P;  4HX3 A;  1UEA A;  4JPA A;  1JH1 A;  3I7G A;  3F16 A;  2Z2D A;  4R3V A;  1SU3 A;  4CTH A;  1HFC A;  3KME A;  2X3C A;  2OW2 A;  4IN9 A;  4PKW A;  3O64 A;  5I0L A;  4GUY A;  4XBH A;  3ZXH A;  4FVL A;  3LIL A;  1D8M A;  4G9L A;  1GO8 P;  3HY7 A;  3LJZ A;  1HTD A;  5BOY A;  1K7I A;  2I47 A;  5CZM A;  2OXW A;  2QPJ A;  4FXY P;  1IAB A;  1OM7 A;  4JIJ A;  2E2D A;  5B5O A;  2KRJ A;  2A8H A;  2JNP A;  1FLS A;  1UTZ A;  1Z3J A;  4ZR5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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