1BKCA

Catalytic domain of tnf-alpha converting enzyme (tace)
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
255
structure length
255
Chain Sequence
DPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.
pubmed doi rcsb
molecule tags Zn-endopeptidase
source organism Homo sapiens
molecule keywords TUMOR NECROSIS FACTOR-ALPHA-CONVERTING ENZYME
total genus 84
structure length 255
sequence length 255
chains with identical sequence C
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 1998-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1bkcA00
4DV8A 3B2ZA 1HY7A 3B92A 1WNIA 1IAGA 1XFXA 3V96B 5D2BA 3LIKA 4ON1A 3CKIA 4L19A 1MMRA 1IAAA 1UMTA 1KUHA 1JH1A 3EWJA 3WV2A 5CZMA 3EDHA 1QJJA 1RM8A 3F18A 1CAQA 3BA0A 1UMSA 1D5JA 2DW0A 1I1IP 1R1IA 2DDYA 3HY7A 3AYKA 2OXZA 2E3XA 2KRJA 1J7NA 3ZUKA 5BOTA 4H76A 3GBOA 1UTTA 2OVZA 1B8YA 3L0VA 2AYKA 2L0RA 2OXUA 1R1HA 1DTHA 1PWUA 1OM6A 4CTHA 3F1AA 5I0LA 1SLNA 2W14A 3EHXA 1YCMA 3KWVC 4L6TA 1ROSA 4FXQA 1Z3JA 2FV9A 2YIGA 1C8TA 4XM7A 1KUGA 3LE9A 1C3IA 3LJGA 1UEAA 4PKVA 2ERQA 1BQOA 1KUIA 3KHIA 1JAPA 1BKCA 2X3CA 2A8HA 1JK3A 2MZEA 1Y0VA 1IACA 4PKUA 4PKQA 1K7IA 4J4MA 3EHYA 3USNA 3ELMA 3RTSA 1ZXVA 3HY9A 2CLTA 1BKCI 5CUHA 2AIGP 5BOYA 1BIWA 1O0TA 2W15A 1CK7A 3I7GA 1CQRA 3P24A 4PKTA 2X7MA 1PWWA 1QICA 3O64A 1HTDA 1MMPA 2E2DA 2WOAA 2OI0A 5BPAA 1QJIA 1KBCA 4H1QA 5JMYA 4EFSA 3KEKA 1AF0A 4AUOA 1K7GA 2XS3A 4GR3A 1JIWP 2J83A 4HMAA 3DL1A 1Y8JA 3OHOA 5H8XA 3UVCA 2W13A 3TVCA 3EDZA 5L7FA 1Y93A 4IJOA 3LJZA 3K7LA 2JT5A 3ZXHA 3K7NA 1FBLA 4IN9A 5I2ZA 1R54A 3KMCA 1JJ9A 3VI1A 4G0DA 1AYKA 4JP4A 1IAEA 1XFYA 1XUCA 5I3MA 1YP1A 3HBVP 4PKRA 1YOUA 4DD8A 1CGEA 3N2VA 1O0QA 4XM8A 3G5CA 2EROA 2Y6CA 2TCLA 4JA1A 3Q2GA 3G42A 1SMPA 4ZR5A 5I4OA 2I47A 3LKAA 1XFUA 2RJPA 4ILWD 4GWMA 1SU3A 2MLRA 4XCTA 1C7KA 2OW1A 2JNPA 2PJTA 4PKWA 5D1TA 1IADA 4AYKA 1Q3AA 1L6JA 4I03A 4WK7A 2D1OA 4WF6A 1R55A 1R1JA 3F19A 1GE7A 2XS4A 3P1VA 1ZVXA 3KEJA 1OM8A 1PWVA 4HX3A 1BKCE 1D8MA 3RTTA 3Q2HA 2Z2DA 1XUDA 3ZVSA 4H49A 3LILA 3LIRA 1GKCA 1K7QA 1KAPP 1XURA 4GUYA 5LABA 1OS9A 3O2XA 1ASTA 2D1NA 4WKIA 1DMTA 5I12A 2USNA 5B5PA 4AXQA 4GF1A 3DPFA 3HDAP 2K9CA 3LMCA 3LGPA 1OS2A 2DW1A 3WV1A 1IABA 1HFSA 1EUBA 2OW2A 3HYGA 1A86A 3EDIA 4GQLA 3LUNA 3LUMA 4H84A 1XFWA 2WO8A 2QPJA 1ATLA 1BM6A 1CGLA 2YB9A 1MNCA 4FU4A 4PKSA 1GE5A 3TSKA 4DF9A 1QIAA 1G4KA 3EDGA 3HDBA 2N8RA 3WV3A 5B5OA 2ERPA 1A85A 1GKDA 3MA2A 4A7BA 3LQ0A 3DSLA 4JQGA 3DWBA 2MLSA 2WO9A 2OY4A 1BZSA 1XFVA 2RJQA 1GXDA 3VTGA 3DNGA 1G05A 4I35A 3U1RA 2V4BA 3HBUP 5D1UA 1XFZA 3AYUA 3F17A 4H2EA 4R3VA 1BUVM 1H71P 2J0TA 4XM6A 1QUAA 1S4BP 1OM7A 1SRPA 1I76A 3LJTA 1FLSA 1AKLA 1ZS0A 4WZVA 1D8FA 3F15A 2MZHA 1B3DA 4DPEA 1CXVA 4Q1LA 966CA 3LQBA 3F16A 1SATA 2POJA 3DPEA 2DW2A 3KMEA 1QIBA 2W0DA 830CA 2OW0A 1JANA 4H82A 4L63A 1G12A 3SHIA 456CA 3I7IA 2OXWA 3HB2P 4AIGA 1BUDA 2OZRA 1BSWA 2X3AA 2DDFA 2W12A 1BQQM 4IUWA 1HOVA 1JKYA 1KUFA 3TT4A 1KUKA 4A3WA 1USNA 4FVLA 1ZP5A 3N2UA 3B8ZA 1HV5A 5D3CA 1JAOA 3OHLA 4H3XA 4GWNA 1MMQA 4FXYP 4QKZA 1PWPA 1EAKA 2HU6A 2JT6A 1EB6A 1MMBA 2FV5A 2Y6DA 1ZXCA 4GR0A 1SLMA 5CXAA 2SRTA 3E8RA 1GE6A 1OO9A 1PWQA 3L0TA 4H30A 1YQYA 5D7WA 3LEAA 1HFCA 1D7XA 4JPAA 4JIJA 3AIGA 1CGFA 1ZTQA 4G9LA 2O3EA 2CKIA 3TS4A 1JAQA 1GO7P 2X3BA 2OY2A 2O36A 5I43A 1CIZA 1RMZA 2K2GA 5D1SA 3KECA 1JIZA 2OW9A 5L79A 3KRYA 3NX7A 1GO8P 1G9KA 2JSDA 2JIHA 2OVXA 4GR8A 1ND1A 1UTZA 2MZIA 4WKEA 4XBHA 1FM1A 3LK8A 1G49A 1I73A 1OMJA
chains in the Genus database with same CATH superfamily
4DV8A 3B2ZA 1HY7A 3B92A 1WNIA 1IAGA 1XFXA 3V96B 5D2BA 3LIKA 4ON1A 3CKIA 4L19A 1MMRA 1IAAA 1UMTA 1KUHA 1JH1A 3EWJA 3WV2A 5CZMA 3EDHA 1QJJA 1RM8A 3F18A 1CAQA 3BA0A 1UMSA 1D5JA 2DW0A 1I1IP 1R1IA 2DDYA 3HY7A 3AYKA 2OXZA 2E3XA 2KRJA 1J7NA 3ZUKA 5BOTA 4H76A 3GBOA 1UTTA 2OVZA 1B8YA 3L0VA 2AYKA 2L0RA 2OXUA 1R1HA 1TVIA 1DTHA 1PWUA 1OM6A 4CTHA 3F1AA 5I0LA 1SLNA 2W14A 3EHXA 1YCMA 3KWVC 4L6TA 1ROSA 4FXQA 1Z3JA 2FV9A 2YIGA 1C8TA 4XM7A 1KUGA 3LE9A 1C3IA 3LJGA 1UEAA 4PKVA 2ERQA 1BQOA 1KUIA 3KHIA 1JAPA 1BKCA 2X3CA 2A8HA 1JK3A 2MZEA 1Y0VA 1IACA 4PKUA 4PKQA 1K7IA 4J4MA 3EHYA 3USNA 3ELMA 3RTSA 1ZXVA 3HY9A 2CLTA 1BKCI 5CUHA 2AIGP 5BOYA 1BIWA 1O0TA 2W15A 1CK7A 3I7GA 1CQRA 3P24A 4PKTA 2X7MA 3DTKA 1PWWA 1QICA 3O64A 1HTDA 1MMPA 2E2DA 2WOAA 2OI0A 5BPAA 1QJIA 1KBCA 4H1QA 5JMYA 4EFSA 3KEKA 1AF0A 4AUOA 1K7GA 2XS3A 4GR3A 1JIWP 2J83A 4HMAA 3DL1A 1Y8JA 3OHOA 5H8XA 3UVCA 2W13A 3TVCA 3EDZA 5L7FA 1Y93A 4IJOA 3LJZA 3K7LA 2JT5A 3ZXHA 3K7NA 1FBLA 4IN9A 5I2ZA 1R54A 3KMCA 1JJ9A 3VI1A 4G0DA 1AYKA 4JP4A 1IAEA 1XFYA 1XUCA 5I3MA 1YP1A 3HBVP 4PKRA 1XM5A 1YOUA 4DD8A 1CGEA 3N2VA 1O0QA 4XM8A 3G5CA 2EROA 2Y6CA 2TCLA 4JA1A 3Q2GA 3G42A 1SMPA 4ZR5A 5I4OA 2I47A 3LKAA 1XFUA 2RJPA 4ILWD 4GWMA 1SU3A 2MLRA 4XCTA 1C7KA 2OW1A 2JNPA 2PJTA 4PKWA 5D1TA 1IADA 4L7AA 4AYKA 1Q3AA 1L6JA 4I03A 4WK7A 2D1OA 4WF6A 1R55A 1R1JA 3F19A 1GE7A 2XS4A 3P1VA 1ZVXA 3KEJA 1OM8A 1PWVA 4HX3A 1BKCE 1D8MA 3RTTA 3Q2HA 2Z2DA 1XUDA 3ZVSA 4H49A 3LILA 3LIRA 1GKCA 1K7QA 1KAPP 1XURA 4GUYA 5LABA 1OS9A 3O2XA 1ASTA 2D1NA 4WKIA 1DMTA 5I12A 2USNA 5B5PA 4AXQA 4GF1A 3DPFA 3HDAP 2K9CA 3LMCA 3LGPA 1OS2A 2DW1A 3WV1A 1IABA 1HFSA 1EUBA 2OW2A 3HYGA 1A86A 3EDIA 4GQLA 3LUNA 1OZ9A 3LUMA 4H84A 1XFWA 2WO8A 2QPJA 1ATLA 1BM6A 1CGLA 2YB9A 1MNCA 4FU4A 4PKSA 1GE5A 3TSKA 4DF9A 1QIAA 1G4KA 3EDGA 3HDBA 2N8RA 3WV3A 5B5OA 2ERPA 1A85A 1GKDA 3MA2A 4A7BA 3LQ0A 3DSLA 4JQGA 3DWBA 2MLSA 2WO9A 3DTIA 2OY4A 1BZSA 1XFVA 2RJQA 1GXDA 3VTGA 3DNGA 1G05A 4I35A 3U1RA 2V4BA 3DTEA 3HBUP 5D1UA 1XFZA 3AYUA 3F17A 4H2EA 4R3VA 1BUVM 1H71P 2J0TA 4XM6A 1QUAA 1S4BP 1OM7A 1SRPA 1I76A 3LJTA 1FLSA 1AKLA 1ZS0A 4WZVA 1D8FA 3F15A 2MZHA 1B3DA 4DPEA 1CXVA 4Q1LA 966CA 3LQBA 3F16A 1SATA 2POJA 3DPEA 2DW2A 3KMEA 1QIBA 2W0DA 830CA 2OW0A 1JANA 4H82A 4L63A 1G12A 1XAXA 3SHIA 456CA 3I7IA 2OXWA 3HB2P 4AIGA 1BUDA 2OZRA 1BSWA 2X3AA 2DDFA 2W12A 1BQQM 4IUWA 1HOVA 1JKYA 1KUFA 3TT4A 1KUKA 4A3WA 1USNA 4FVLA 1ZP5A 3N2UA 3B8ZA 1HV5A 5D3CA 1JAOA 3OHLA 4H3XA 4GWNA 1MMQA 4FXYP 4QKZA 1PWPA 1EAKA 2HU6A 2JT6A 1EB6A 1MMBA 2FV5A 2Y6DA 1ZXCA 4GR0A 1SLMA 5CXAA 2SRTA 3E8RA 1GE6A 1OO9A 1PWQA 3L0TA 4H30A 1YQYA 5D7WA 3LEAA 1HFCA 1D7XA 4JPAA 4JIJA 3AIGA 1CGFA 1ZTQA 4G9LA 2O3EA 2CKIA 3TS4A 1JAQA 1GO7P 2X3BA 2YUFA 2OY2A 2O36A 5I43A 1CIZA 1RMZA 2K2GA 5D1SA 3KECA 1JIZA 2OW9A 5L79A 3KRYA 3NX7A 1GO8P 1G9KA 2JSDA 2JIHA 2OVXA 4GR8A 1ND1A 1UTZA 2MZIA 4WKEA 4XBHA 1FM1A 3LK8A 1G49A 1I73A 1OMJA
chains in the Genus database with same CATH topology
4DV8A 3B2ZA 1HY7A 3B92A 1WNIA 1IAGA 1XFXA 3V96B 5D2BA 3LIKA 4ON1A 3CKIA 4L19A 1MMRA 1IAAA 1UMTA 1KUHA 1JH1A 3EWJA 3WV2A 5CZMA 3EDHA 1QJJA 1RM8A 3F18A 1CAQA 3BA0A 1UMSA 1D5JA 2DW0A 1I1IP 1R1IA 2DDYA 3HY7A 3AYKA 2OXZA 2E3XA 2KRJA 1J7NA 3ZUKA 5BOTA 4H76A 3GBOA 1UTTA 2OVZA 1B8YA 3L0VA 2AYKA 2L0RA 2OXUA 1R1HA 1DTHA 1PWUA 1OM6A 4CTHA 3F1AA 5I0LA 1SLNA 2W14A 3EHXA 1YCMA 3KWVC 4L6TA 1ROSA 4FXQA 1Z3JA 2FV9A 2YIGA 1C8TA 4XM7A 1KUGA 3LE9A 1C3IA 3LJGA 1UEAA 4PKVA 2ERQA 1BQOA 1KUIA 3KHIA 1JAPA 1BKCA 2X3CA 2A8HA 1JK3A 2MZEA 1Y0VA 1IACA 4PKUA 4PKQA 1K7IA 4J4MA 3EHYA 3USNA 3ELMA 3RTSA 1ZXVA 3HY9A 2CLTA 1BKCI 5CUHA 2AIGP 5BOYA 1BIWA 1O0TA 2W15A 1CK7A 3I7GA 1CQRA 3P24A 4PKTA 2X7MA 3DTKA 1PWWA 1QICA 3O64A 1HTDA 1MMPA 2E2DA 2WOAA 2OI0A 5BPAA 1QJIA 1KBCA 4H1QA 5JMYA 4EFSA 3KEKA 1AF0A 4AUOA 1K7GA 2XS3A 4GR3A 1JIWP 2J83A 4HMAA 3DL1A 1Y8JA 3OHOA 5H8XA 3UVCA 2W13A 3TVCA 3EDZA 5L7FA 1Y93A 4IJOA 3LJZA 3K7LA 2JT5A 3ZXHA 3K7NA 1FBLA 4IN9A 5I2ZA 1R54A 3KMCA 1JJ9A 3VI1A 4G0DA 1AYKA 4JP4A 1IAEA 1XFYA 1XUCA 5I3MA 1YP1A 3HBVP 4PKRA 1YOUA 4DD8A 1CGEA 3N2VA 1O0QA 4XM8A 3G5CA 2EROA 2Y6CA 2TCLA 4JA1A 3Q2GA 3G42A 1SMPA 4ZR5A 5I4OA 2I47A 3LKAA 1XFUA 2RJPA 4ILWD 4GWMA 1SU3A 2MLRA 4XCTA 1C7KA 2OW1A 2JNPA 2PJTA 4PKWA 5D1TA 1IADA 4L7AA 4AYKA 1Q3AA 1L6JA 4I03A 4WK7A 2D1OA 4WF6A 1R55A 1R1JA 3F19A 1GE7A 2XS4A 3P1VA 1ZVXA 3KEJA 1OM8A 1PWVA 4HX3A 1BKCE 1D8MA 3RTTA 3Q2HA 2Z2DA 1XUDA 3ZVSA 4H49A 3LILA 3LIRA 1GKCA 1K7QA 1KAPP 1XURA 4GUYA 5LABA 1OS9A 3O2XA 1ASTA 2D1NA 4WKIA 1DMTA 5I12A 2USNA 5B5PA 4AXQA 4GF1A 3DPFA 3HDAP 2K9CA 3LMCA 3LGPA 1OS2A 2DW1A 3WV1A 1IABA 1HFSA 1EUBA 2OW2A 3HYGA 1A86A 3EDIA 4GQLA 3LUNA 3LUMA 4H84A 1XFWA 2WO8A 2QPJA 1ATLA 1BM6A 1CGLA 2YB9A 1MNCA 4FU4A 4PKSA 1GE5A 3TSKA 4DF9A 1QIAA 1G4KA 3EDGA 3HDBA 2N8RA 3WV3A 5B5OA 2ERPA 1A85A 1GKDA 3MA2A 4A7BA 3LQ0A 3DSLA 4JQGA 3DWBA 2MLSA 2WO9A 3DTIA 2OY4A 1BZSA 1XFVA 2RJQA 1GXDA 3VTGA 3DNGA 1G05A 4I35A 3U1RA 2V4BA 3DTEA 3HBUP 5D1UA 1XFZA 3AYUA 3F17A 4H2EA 4R3VA 1BUVM 1H71P 2J0TA 4XM6A 1QUAA 1S4BP 1OM7A 1SRPA 1I76A 3LJTA 1FLSA 1AKLA 1ZS0A 4WZVA 1D8FA 3F15A 2MZHA 1B3DA 4DPEA 1CXVA 4Q1LA 966CA 3LQBA 3F16A 1SATA 2POJA 3DPEA 2DW2A 3KMEA 1QIBA 2W0DA 830CA 2OW0A 1JANA 4H82A 4L63A 1G12A 3SHIA 456CA 3I7IA 2OXWA 3HB2P 4AIGA 1BUDA 2OZRA 1BSWA 2X3AA 2DDFA 2W12A 1BQQM 4IUWA 1HOVA 1JKYA 1KUFA 3TT4A 1KUKA 4A3WA 1USNA 4FVLA 1ZP5A 3N2UA 3B8ZA 1HV5A 5D3CA 1JAOA 3OHLA 4H3XA 4GWNA 1MMQA 4FXYP 4QKZA 1PWPA 1EAKA 2HU6A 2JT6A 1EB6A 1MMBA 2FV5A 2Y6DA 1ZXCA 4GR0A 1SLMA 5CXAA 2SRTA 3E8RA 1GE6A 1OO9A 1PWQA 3L0TA 4H30A 1YQYA 5D7WA 3LEAA 1HFCA 1D7XA 4JPAA 4JIJA 3AIGA 1CGFA 1ZTQA 4G9LA 2O3EA 2CKIA 3TS4A 1JAQA 1GO7P 2X3BA 2YUFA 2OY2A 2O36A 5I43A 1CIZA 1RMZA 2K2GA 5D1SA 3KECA 1JIZA 2OW9A 5L79A 3KRYA 3NX7A 1GO8P 1G9KA 2JSDA 2JIHA 2OVXA 4GR8A 1ND1A 1UTZA 2MZIA 4WKEA 4XBHA 1FM1A 3LK8A 1G49A 1I73A 1OMJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DV8 A;  3B2Z A;  1HY7 A;  3B92 A;  1WNI A;  1IAG A;  1XFX A;  3V96 B;  5D2B A;  3LIK A;  4ON1 A;  3CKI A;  4L19 A;  1MMR A;  1IAA A;  1UMT A;  1KUH A;  1JH1 A;  3EWJ A;  3WV2 A;  5CZM A;  3EDH A;  1QJJ A;  1RM8 A;  3F18 A;  1CAQ A;  3BA0 A;  1UMS A;  1D5J A;  2DW0 A;  1I1I P;  1R1I A;  2DDY A;  3HY7 A;  3AYK A;  2OXZ A;  2E3X A;  2KRJ A;  1J7N A;  3ZUK A;  5BOT A;  4H76 A;  3GBO A;  1UTT A;  2OVZ A;  1B8Y A;  3L0V A;  2AYK A;  2L0R A;  2OXU A;  1R1H A;  1DTH A;  1PWU A;  1OM6 A;  4CTH A;  3F1A A;  5I0L A;  1SLN A;  2W14 A;  3EHX A;  1YCM A;  3KWV C;  4L6T A;  1ROS A;  4FXQ A;  1Z3J A;  2FV9 A;  2YIG A;  1C8T A;  4XM7 A;  1KUG A;  3LE9 A;  1C3I A;  3LJG A;  1UEA A;  4PKV A;  2ERQ A;  1BQO A;  1KUI A;  3KHI A;  1JAP A;  1BKC A;  2X3C A;  2A8H A;  1JK3 A;  2MZE A;  1Y0V A;  1IAC A;  4PKU A;  4PKQ A;  1K7I A;  4J4M A;  3EHY A;  3USN A;  3ELM A;  3RTS A;  1ZXV A;  3HY9 A;  2CLT A;  1BKC I;  5CUH A;  2AIG P;  5BOY A;  1BIW A;  1O0T A;  2W15 A;  1CK7 A;  3I7G A;  1CQR A;  3P24 A;  4PKT A;  2X7M A;  1PWW A;  1QIC A;  3O64 A;  1HTD A;  1MMP A;  2E2D A;  2WOA A;  2OI0 A;  5BPA A;  1QJI A;  1KBC A;  4H1Q A;  5JMY A;  4EFS A;  3KEK A;  1AF0 A;  4AUO A;  1K7G A;  2XS3 A;  4GR3 A;  1JIW P;  2J83 A;  4HMA A;  3DL1 A;  1Y8J A;  3OHO A;  5H8X A;  3UVC A;  2W13 A;  3TVC A;  3EDZ A;  5L7F A;  1Y93 A;  4IJO A;  3LJZ A;  3K7L A;  2JT5 A;  3ZXH A;  3K7N A;  1FBL A;  4IN9 A;  5I2Z A;  1R54 A;  3KMC A;  1JJ9 A;  3VI1 A;  4G0D A;  1AYK A;  4JP4 A;  1IAE A;  1XFY A;  1XUC A;  5I3M A;  1YP1 A;  3HBV P;  4PKR A;  1YOU A;  4DD8 A;  1CGE A;  3N2V A;  1O0Q A;  4XM8 A;  3G5C A;  2ERO A;  2Y6C A;  2TCL A;  4JA1 A;  3Q2G A;  3G42 A;  1SMP A;  4ZR5 A;  5I4O A;  2I47 A;  3LKA A;  1XFU A;  2RJP A;  4ILW D;  4GWM A;  1SU3 A;  2MLR A;  4XCT A;  1C7K A;  2OW1 A;  2JNP A;  2PJT A;  4PKW A;  5D1T A;  1IAD A;  4AYK A;  1Q3A A;  1L6J A;  4I03 A;  4WK7 A;  2D1O A;  4WF6 A;  1R55 A;  1R1J A;  3F19 A;  1GE7 A;  2XS4 A;  3P1V A;  1ZVX A;  3KEJ A;  1OM8 A;  1PWV A;  4HX3 A;  1BKC E;  1D8M A;  3RTT A;  3Q2H A;  2Z2D A;  1XUD A;  3ZVS A;  4H49 A;  3LIL A;  3LIR A;  1GKC A;  1K7Q A;  1KAP P;  1XUR A;  4GUY A;  5LAB A;  1OS9 A;  3O2X A;  1AST A;  2D1N A;  4WKI A;  1DMT A;  5I12 A;  2USN A;  5B5P A;  4AXQ A;  4GF1 A;  3DPF A;  3HDA P;  2K9C A;  3LMC A;  3LGP A;  1OS2 A;  2DW1 A;  3WV1 A;  1IAB A;  1HFS A;  1EUB A;  2OW2 A;  3HYG A;  1A86 A;  3EDI A;  4GQL A;  3LUN A;  3LUM A;  4H84 A;  1XFW A;  2WO8 A;  2QPJ A;  1ATL A;  1BM6 A;  1CGL A;  2YB9 A;  1MNC A;  4FU4 A;  4PKS A;  1GE5 A;  3TSK A;  4DF9 A;  1QIA A;  1G4K A;  3EDG A;  3HDB A;  2N8R A;  3WV3 A;  5B5O A;  2ERP A;  1A85 A;  1GKD A;  3MA2 A;  4A7B A;  3LQ0 A;  3DSL A;  4JQG A;  3DWB A;  2MLS A;  2WO9 A;  2OY4 A;  1BZS A;  1XFV A;  2RJQ A;  1GXD A;  3VTG A;  3DNG A;  1G05 A;  4I35 A;  3U1R A;  2V4B A;  3HBU P;  5D1U A;  1XFZ A;  3AYU A;  3F17 A;  4H2E A;  4R3V A;  1BUV M;  1H71 P;  2J0T A;  4XM6 A;  1QUA A;  1S4B P;  1OM7 A;  1SRP A;  1I76 A;  3LJT A;  1FLS A;  1AKL A;  1ZS0 A;  4WZV A;  1D8F A;  3F15 A;  2MZH A;  1B3D A;  4DPE A;  1CXV A;  4Q1L A;  966C A;  3LQB A;  3F16 A;  1SAT A;  2POJ A;  3DPE A;  2DW2 A;  3KME A;  1QIB A;  2W0D A;  830C A;  2OW0 A;  1JAN A;  4H82 A;  4L63 A;  1G12 A;  3SHI A;  456C A;  3I7I A;  2OXW A;  3HB2 P;  4AIG A;  1BUD A;  2OZR A;  1BSW A;  2X3A A;  2DDF A;  2W12 A;  1BQQ M;  4IUW A;  1HOV A;  1JKY A;  1KUF A;  3TT4 A;  1KUK A;  4A3W A;  1USN A;  4FVL A;  1ZP5 A;  3N2U A;  3B8Z A;  1HV5 A;  5D3C A;  1JAO A;  3OHL A;  4H3X A;  4GWN A;  1MMQ A;  4FXY P;  4QKZ A;  1PWP A;  1EAK A;  2HU6 A;  2JT6 A;  1EB6 A;  1MMB A;  2FV5 A;  2Y6D A;  1ZXC A;  4GR0 A;  1SLM A;  5CXA A;  2SRT A;  3E8R A;  1GE6 A;  1OO9 A;  1PWQ A;  3L0T A;  4H30 A;  1YQY A;  5D7W A;  3LEA A;  1HFC A;  1D7X A;  4JPA A;  4JIJ A;  3AIG A;  1CGF A;  1ZTQ A;  4G9L A;  2O3E A;  2CKI A;  3TS4 A;  1JAQ A;  1GO7 P;  2X3B A;  2OY2 A;  2O36 A;  5I43 A;  1CIZ A;  1RMZ A;  2K2G A;  5D1S A;  3KEC A;  1JIZ A;  2OW9 A;  5L79 A;  3KRY A;  3NX7 A;  1GO8 P;  1G9K A;  2JSD A;  2JIH A;  2OVX A;  4GR8 A;  1ND1 A;  1UTZ A;  2MZI A;  4WKE A;  4XBH A;  1FM1 A;  3LK8 A;  1G49 A;  1I73 A;  1OMJ A; 
#chains in the Genus database with same CATH topology
 4DV8 A;  3B2Z A;  1HY7 A;  3B92 A;  1WNI A;  1IAG A;  1XFX A;  3V96 B;  5D2B A;  3LIK A;  4ON1 A;  3CKI A;  4L19 A;  1MMR A;  1IAA A;  1UMT A;  1KUH A;  1JH1 A;  3EWJ A;  3WV2 A;  5CZM A;  3EDH A;  1QJJ A;  1RM8 A;  3F18 A;  1CAQ A;  3BA0 A;  1UMS A;  1D5J A;  2DW0 A;  1I1I P;  1R1I A;  2DDY A;  3HY7 A;  3AYK A;  2OXZ A;  2E3X A;  2KRJ A;  1J7N A;  3ZUK A;  5BOT A;  4H76 A;  3GBO A;  1UTT A;  2OVZ A;  1B8Y A;  3L0V A;  2AYK A;  2L0R A;  2OXU A;  1R1H A;  1TVI A;  1DTH A;  1PWU A;  1OM6 A;  4CTH A;  3F1A A;  5I0L A;  1SLN A;  2W14 A;  3EHX A;  1YCM A;  3KWV C;  4L6T A;  1ROS A;  4FXQ A;  1Z3J A;  2FV9 A;  2YIG A;  1C8T A;  4XM7 A;  1KUG A;  3LE9 A;  1C3I A;  3LJG A;  1UEA A;  4PKV A;  2ERQ A;  1BQO A;  1KUI A;  3KHI A;  1JAP A;  1BKC A;  2X3C A;  2A8H A;  1JK3 A;  2MZE A;  1Y0V A;  1IAC A;  4PKU A;  4PKQ A;  1K7I A;  4J4M A;  3EHY A;  3USN A;  3ELM A;  3RTS A;  1ZXV A;  3HY9 A;  2CLT A;  1BKC I;  5CUH A;  2AIG P;  5BOY A;  1BIW A;  1O0T A;  2W15 A;  1CK7 A;  3I7G A;  1CQR A;  3P24 A;  4PKT A;  2X7M A;  3DTK A;  1PWW A;  1QIC A;  3O64 A;  1HTD A;  1MMP A;  2E2D A;  2WOA A;  2OI0 A;  5BPA A;  1QJI A;  1KBC A;  4H1Q A;  5JMY A;  4EFS A;  3KEK A;  1AF0 A;  4AUO A;  1K7G A;  2XS3 A;  4GR3 A;  1JIW P;  2J83 A;  4HMA A;  3DL1 A;  1Y8J A;  3OHO A;  5H8X A;  3UVC A;  2W13 A;  3TVC A;  3EDZ A;  5L7F A;  1Y93 A;  4IJO A;  3LJZ A;  3K7L A;  2JT5 A;  3ZXH A;  3K7N A;  1FBL A;  4IN9 A;  5I2Z A;  1R54 A;  3KMC A;  1JJ9 A;  3VI1 A;  4G0D A;  1AYK A;  4JP4 A;  1IAE A;  1XFY A;  1XUC A;  5I3M A;  1YP1 A;  3HBV P;  4PKR A;  1XM5 A;  1YOU A;  4DD8 A;  1CGE A;  3N2V A;  1O0Q A;  4XM8 A;  3G5C A;  2ERO A;  2Y6C A;  2TCL A;  4JA1 A;  3Q2G A;  3G42 A;  1SMP A;  4ZR5 A;  5I4O A;  2I47 A;  3LKA A;  1XFU A;  2RJP A;  4ILW D;  4GWM A;  1SU3 A;  2MLR A;  4XCT A;  1C7K A;  2OW1 A;  2JNP A;  2PJT A;  4PKW A;  5D1T A;  1IAD A;  4L7A A;  4AYK A;  1Q3A A;  1L6J A;  4I03 A;  4WK7 A;  2D1O A;  4WF6 A;  1R55 A;  1R1J A;  3F19 A;  1GE7 A;  2XS4 A;  3P1V A;  1ZVX A;  3KEJ A;  1OM8 A;  1PWV A;  4HX3 A;  1BKC E;  1D8M A;  3RTT A;  3Q2H A;  2Z2D A;  1XUD A;  3ZVS A;  4H49 A;  3LIL A;  3LIR A;  1GKC A;  1K7Q A;  1KAP P;  1XUR A;  4GUY A;  5LAB A;  1OS9 A;  3O2X A;  1AST A;  2D1N A;  4WKI A;  1DMT A;  5I12 A;  2USN A;  5B5P A;  4AXQ A;  4GF1 A;  3DPF A;  3HDA P;  2K9C A;  3LMC A;  3LGP A;  1OS2 A;  2DW1 A;  3WV1 A;  1IAB A;  1HFS A;  1EUB A;  2OW2 A;  3HYG A;  1A86 A;  3EDI A;  4GQL A;  3LUN A;  1OZ9 A;  3LUM A;  4H84 A;  1XFW A;  2WO8 A;  2QPJ A;  1ATL A;  1BM6 A;  1CGL A;  2YB9 A;  1MNC A;  4FU4 A;  4PKS A;  1GE5 A;  3TSK A;  4DF9 A;  1QIA A;  1G4K A;  3EDG A;  3HDB A;  2N8R A;  3WV3 A;  5B5O A;  2ERP A;  1A85 A;  1GKD A;  3MA2 A;  4A7B A;  3LQ0 A;  3DSL A;  4JQG A;  3DWB A;  2MLS A;  2WO9 A;  3DTI A;  2OY4 A;  1BZS A;  1XFV A;  2RJQ A;  1GXD A;  3VTG A;  3DNG A;  1G05 A;  4I35 A;  3U1R A;  2V4B A;  3DTE A;  3HBU P;  5D1U A;  1XFZ A;  3AYU A;  3F17 A;  4H2E A;  4R3V A;  1BUV M;  1H71 P;  2J0T A;  4XM6 A;  1QUA A;  1S4B P;  1OM7 A;  1SRP A;  1I76 A;  3LJT A;  1FLS A;  1AKL A;  1ZS0 A;  4WZV A;  1D8F A;  3F15 A;  2MZH A;  1B3D A;  4DPE A;  1CXV A;  4Q1L A;  966C A;  3LQB A;  3F16 A;  1SAT A;  2POJ A;  3DPE A;  2DW2 A;  3KME A;  1QIB A;  2W0D A;  830C A;  2OW0 A;  1JAN A;  4H82 A;  4L63 A;  1G12 A;  1XAX A;  3SHI A;  456C A;  3I7I A;  2OXW A;  3HB2 P;  4AIG A;  1BUD A;  2OZR A;  1BSW A;  2X3A A;  2DDF A;  2W12 A;  1BQQ M;  4IUW A;  1HOV A;  1JKY A;  1KUF A;  3TT4 A;  1KUK A;  4A3W A;  1USN A;  4FVL A;  1ZP5 A;  3N2U A;  3B8Z A;  1HV5 A;  5D3C A;  1JAO A;  3OHL A;  4H3X A;  4GWN A;  1MMQ A;  4FXY P;  4QKZ A;  1PWP A;  1EAK A;  2HU6 A;  2JT6 A;  1EB6 A;  1MMB A;  2FV5 A;  2Y6D A;  1ZXC A;  4GR0 A;  1SLM A;  5CXA A;  2SRT A;  3E8R A;  1GE6 A;  1OO9 A;  1PWQ A;  3L0T A;  4H30 A;  1YQY A;  5D7W A;  3LEA A;  1HFC A;  1D7X A;  4JPA A;  4JIJ A;  3AIG A;  1CGF A;  1ZTQ A;  4G9L A;  2O3E A;  2CKI A;  3TS4 A;  1JAQ A;  1GO7 P;  2X3B A;  2YUF A;  2OY2 A;  2O36 A;  5I43 A;  1CIZ A;  1RMZ A;  2K2G A;  5D1S A;  3KEC A;  1JIZ A;  2OW9 A;  5L79 A;  3KRY A;  3NX7 A;  1GO8 P;  1G9K A;  2JSD A;  2JIH A;  2OVX A;  4GR8 A;  1ND1 A;  1UTZ A;  2MZI A;  4WKE A;  4XBH A;  1FM1 A;  3LK8 A;  1G49 A;  1I73 A;  1OMJ A; 
#chains in the Genus database with same CATH homology
 4DV8 A;  3B2Z A;  1HY7 A;  3B92 A;  1WNI A;  1IAG A;  1XFX A;  3V96 B;  5D2B A;  3LIK A;  4ON1 A;  3CKI A;  4L19 A;  1MMR A;  1IAA A;  1UMT A;  1KUH A;  1JH1 A;  3EWJ A;  3WV2 A;  5CZM A;  3EDH A;  1QJJ A;  1RM8 A;  3F18 A;  1CAQ A;  3BA0 A;  1UMS A;  1D5J A;  2DW0 A;  1I1I P;  1R1I A;  2DDY A;  3HY7 A;  3AYK A;  2OXZ A;  2E3X A;  2KRJ A;  1J7N A;  3ZUK A;  5BOT A;  4H76 A;  3GBO A;  1UTT A;  2OVZ A;  1B8Y A;  3L0V A;  2AYK A;  2L0R A;  2OXU A;  1R1H A;  1DTH A;  1PWU A;  1OM6 A;  4CTH A;  3F1A A;  5I0L A;  1SLN A;  2W14 A;  3EHX A;  1YCM A;  3KWV C;  4L6T A;  1ROS A;  4FXQ A;  1Z3J A;  2FV9 A;  2YIG A;  1C8T A;  4XM7 A;  1KUG A;  3LE9 A;  1C3I A;  3LJG A;  1UEA A;  4PKV A;  2ERQ A;  1BQO A;  1KUI A;  3KHI A;  1JAP A;  1BKC A;  2X3C A;  2A8H A;  1JK3 A;  2MZE A;  1Y0V A;  1IAC A;  4PKU A;  4PKQ A;  1K7I A;  4J4M A;  3EHY A;  3USN A;  3ELM A;  3RTS A;  1ZXV A;  3HY9 A;  2CLT A;  1BKC I;  5CUH A;  2AIG P;  5BOY A;  1BIW A;  1O0T A;  2W15 A;  1CK7 A;  3I7G A;  1CQR A;  3P24 A;  4PKT A;  2X7M A;  3DTK A;  1PWW A;  1QIC A;  3O64 A;  1HTD A;  1MMP A;  2E2D A;  2WOA A;  2OI0 A;  5BPA A;  1QJI A;  1KBC A;  4H1Q A;  5JMY A;  4EFS A;  3KEK A;  1AF0 A;  4AUO A;  1K7G A;  2XS3 A;  4GR3 A;  1JIW P;  2J83 A;  4HMA A;  3DL1 A;  1Y8J A;  3OHO A;  5H8X A;  3UVC A;  2W13 A;  3TVC A;  3EDZ A;  5L7F A;  1Y93 A;  4IJO A;  3LJZ A;  3K7L A;  2JT5 A;  3ZXH A;  3K7N A;  1FBL A;  4IN9 A;  5I2Z A;  1R54 A;  3KMC A;  1JJ9 A;  3VI1 A;  4G0D A;  1AYK A;  4JP4 A;  1IAE A;  1XFY A;  1XUC A;  5I3M A;  1YP1 A;  3HBV P;  4PKR A;  1YOU A;  4DD8 A;  1CGE A;  3N2V A;  1O0Q A;  4XM8 A;  3G5C A;  2ERO A;  2Y6C A;  2TCL A;  4JA1 A;  3Q2G A;  3G42 A;  1SMP A;  4ZR5 A;  5I4O A;  2I47 A;  3LKA A;  1XFU A;  2RJP A;  4ILW D;  4GWM A;  1SU3 A;  2MLR A;  4XCT A;  1C7K A;  2OW1 A;  2JNP A;  2PJT A;  4PKW A;  5D1T A;  1IAD A;  4L7A A;  4AYK A;  1Q3A A;  1L6J A;  4I03 A;  4WK7 A;  2D1O A;  4WF6 A;  1R55 A;  1R1J A;  3F19 A;  1GE7 A;  2XS4 A;  3P1V A;  1ZVX A;  3KEJ A;  1OM8 A;  1PWV A;  4HX3 A;  1BKC E;  1D8M A;  3RTT A;  3Q2H A;  2Z2D A;  1XUD A;  3ZVS A;  4H49 A;  3LIL A;  3LIR A;  1GKC A;  1K7Q A;  1KAP P;  1XUR A;  4GUY A;  5LAB A;  1OS9 A;  3O2X A;  1AST A;  2D1N A;  4WKI A;  1DMT A;  5I12 A;  2USN A;  5B5P A;  4AXQ A;  4GF1 A;  3DPF A;  3HDA P;  2K9C A;  3LMC A;  3LGP A;  1OS2 A;  2DW1 A;  3WV1 A;  1IAB A;  1HFS A;  1EUB A;  2OW2 A;  3HYG A;  1A86 A;  3EDI A;  4GQL A;  3LUN A;  3LUM A;  4H84 A;  1XFW A;  2WO8 A;  2QPJ A;  1ATL A;  1BM6 A;  1CGL A;  2YB9 A;  1MNC A;  4FU4 A;  4PKS A;  1GE5 A;  3TSK A;  4DF9 A;  1QIA A;  1G4K A;  3EDG A;  3HDB A;  2N8R A;  3WV3 A;  5B5O A;  2ERP A;  1A85 A;  1GKD A;  3MA2 A;  4A7B A;  3LQ0 A;  3DSL A;  4JQG A;  3DWB A;  2MLS A;  2WO9 A;  3DTI A;  2OY4 A;  1BZS A;  1XFV A;  2RJQ A;  1GXD A;  3VTG A;  3DNG A;  1G05 A;  4I35 A;  3U1R A;  2V4B A;  3DTE A;  3HBU P;  5D1U A;  1XFZ A;  3AYU A;  3F17 A;  4H2E A;  4R3V A;  1BUV M;  1H71 P;  2J0T A;  4XM6 A;  1QUA A;  1S4B P;  1OM7 A;  1SRP A;  1I76 A;  3LJT A;  1FLS A;  1AKL A;  1ZS0 A;  4WZV A;  1D8F A;  3F15 A;  2MZH A;  1B3D A;  4DPE A;  1CXV A;  4Q1L A;  966C A;  3LQB A;  3F16 A;  1SAT A;  2POJ A;  3DPE A;  2DW2 A;  3KME A;  1QIB A;  2W0D A;  830C A;  2OW0 A;  1JAN A;  4H82 A;  4L63 A;  1G12 A;  3SHI A;  456C A;  3I7I A;  2OXW A;  3HB2 P;  4AIG A;  1BUD A;  2OZR A;  1BSW A;  2X3A A;  2DDF A;  2W12 A;  1BQQ M;  4IUW A;  1HOV A;  1JKY A;  1KUF A;  3TT4 A;  1KUK A;  4A3W A;  1USN A;  4FVL A;  1ZP5 A;  3N2U A;  3B8Z A;  1HV5 A;  5D3C A;  1JAO A;  3OHL A;  4H3X A;  4GWN A;  1MMQ A;  4FXY P;  4QKZ A;  1PWP A;  1EAK A;  2HU6 A;  2JT6 A;  1EB6 A;  1MMB A;  2FV5 A;  2Y6D A;  1ZXC A;  4GR0 A;  1SLM A;  5CXA A;  2SRT A;  3E8R A;  1GE6 A;  1OO9 A;  1PWQ A;  3L0T A;  4H30 A;  1YQY A;  5D7W A;  3LEA A;  1HFC A;  1D7X A;  4JPA A;  4JIJ A;  3AIG A;  1CGF A;  1ZTQ A;  4G9L A;  2O3E A;  2CKI A;  3TS4 A;  1JAQ A;  1GO7 P;  2X3B A;  2YUF A;  2OY2 A;  2O36 A;  5I43 A;  1CIZ A;  1RMZ A;  2K2G A;  5D1S A;  3KEC A;  1JIZ A;  2OW9 A;  5L79 A;  3KRY A;  3NX7 A;  1GO8 P;  1G9K A;  2JSD A;  2JIH A;  2OVX A;  4GR8 A;  1ND1 A;  1UTZ A;  2MZI A;  4WKE A;  4XBH A;  1FM1 A;  3LK8 A;  1G49 A;  1I73 A;  1OMJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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