1D7XA

Crystal structure of mmp3 complexed with a modified proline scaffold based inhibitor.
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
169
structure length
169
Chain Sequence
FRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design, synthesis, and biological evaluation of matrix metalloproteinase inhibitors derived from a modified proline scaffold.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords STROMELYSIN-1 PRECURSOR
total genus 46
structure length 169
sequence length 169
chains with identical sequence B
ec nomenclature ec 3.4.24.17: Stromelysin 1.
pdb deposition date 1999-10-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1d7xA00
4EFSA 4XM6A 1CGLA 4A7BA 2JSDA 1HY7A 1UEAA 1AKLA 4GUYA 2HU6A 5H8XA 1XFUA 1XFYA 4FXQA 2RJQA 1SLNA 4H76A 3LJZA 3TVCA 3I7IA 4H82A 2D1OA 1FBLA 1D8FA 5I43A 4I35A 2A8HA 1CQRA 2O36A 2K9CA 5JMYA 1EUBA 2OXUA 3N2UA 2L0RA 2RJPA 1C7KA 2XS4A 1J7NA 5L79A 2X7MA 3TSKA 1GO7P 5B5PA 1EB6A 2D1NA 2DW1A 2JT5A 1MMPA 2MLRA 2DDYA 3UVCA 3ZXHA 1RM8A 4H49A 2X3AA 2OVXA 3KECA 1JJ9A 3Q2GA 2XS3A 2MLSA 4PKUA 4GWMA 4WKIA 3LGPA 1BQOA 1CXVA 1SU3A 2X3CA 1B8YA 1ATLA 1H71P 1BKCI 3EHYA 3ZUKA 3G42A 1KBCA 1BSWA 1OM6A 5I12A 2J0TA 4QKZA 4JPAA 4IUWA 2OW2A 1AF0A 4AIGA 4AXQA 1PWUA 2DW0A 3EWJA 1I1IP 1AYKA 3EDGA 4XM8A 1DMTA 4GWNA 1CK7A 2W14A 1OS2A 1YQYA 1ND1A 2W0DA 3EDHA 1GXDA 4H30A 3B92A 1CGFA 1CAQA 4XBHA 2OI0A 5LABA 1IAGA 3DNGA 4G0DA 3V96B 1D8MA 3HBUP 1L6JA 2YB9A 5I0LA 3RTSA 3L0TA 2Y6CA 5D1SA 3KEKA 4DF9A 1Q3AA 1RMZA 4AYKA 4PKRA 1KUHA 3DL1A 2FV9A 4H3XA 1SLMA 2OW0A 3EDIA 1IACA 3OHOA 4DV8A 3VTGA 2DDFA 4WF6A 5I3MA 3L0VA 4L63A 2EROA 3P24A 3F17A 4PKWA 1MNCA 4H2EA 1PWWA 3GBOA 3HY9A 3VI1A 1MMQA 1BIWA 1I73A 4GR0A 3DWBA 1XUCA 1OM8A 5BOTA 5D2BA 456CA 2JNPA 2FV5A 4Q1LA 3NX7A 1GE6A 1JAQA 3LK8A 4XM7A 1Z3JA 3LJTA 3G5CA 1YOUA 3HDAP 1O0QA 3B8ZA 1JAOA 3KRYA 1JH1A 3DPEA 5D1UA 2PJTA 1GE5A 1ZVXA 3KMEA 2ERPA 2W12A 4A3WA 1IAAA 1S4BP 3LUMA 4L6TA 3LUNA 5I2ZA 1C8TA 3K7NA 4GR8A 2YIGA 4PKQA 1ZXCA 2OXWA 3U1RA 2WO9A 3Q2HA 5L7FA 1QIAA 1OM7A 3AYUA 3HYGA 3KHIA 2AIGP 1OMJA 1CIZA 1K7IA 1OS9A 1UMTA 1WNIA 830CA 3AYKA 4DD8A 2OW9A 3KEJA 3OHLA 4JA1A 2KRJA 3RTTA 3WV2A 1O0TA 3LIRA 2E2DA 1XFZA 3E8RA 1JANA 1PWVA 2Y6DA 3EHXA 2QPJA 4IN9A 3HB2P 1XFWA 3EDZA 1BUVM 2POJA 4JP4A 1SRPA 1G05A 1KAPP 1GO8P 3AIGA 3K7LA 1I76A 1IAEA 2CLTA 3WV3A 5CXAA 2I47A 4I03A 3KWVC 1KUKA 3I7GA 4L19A 1Y0VA 966CA 1JAPA 3KMCA 3WV1A 2OY2A 1QICA 4J4MA 1XUDA 3LKAA 1KUFA 1G4KA 3LQBA 4AUOA 3P1VA 1D5JA 3F19A 3LIKA 4FU4A 1ZP5A 3HBVP 1R1HA 4XCTA 1HOVA 1K7QA 1HFSA 1PWQA 1JK3A 4IJOA 2OVZA 3F16A 4GQLA 1IABA 1MMBA 3B2ZA 2J83A 4PKTA 4PKVA 2DW2A 2OXZA 2MZHA 1CGEA 2V4BA 3F15A 4H1QA 2N8RA 3HY7A 3USNA 1IADA 3F18A 1QUAA 1Y8JA 2MZEA 1XFXA 3LQ0A 2W15A 1HFCA 4HMAA 3O64A 1UMSA 2OW1A 2ERQA 1SATA 4ZR5A 1BZSA 2SRTA 4WKEA 1GKCA 5B5OA 1BM6A 1PWPA 1QJJA 2MZIA 5CZMA 1KUIA 1D7XA 2JT6A 1R55A 4DPEA 1USNA 5BPAA 1JKYA 1EAKA 1ASTA 2OY4A 2Z2DA 1R1IA 1ZXVA 1YP1A 2K2GA 2X3BA 2AYKA 2USNA 1BKCA 1A86A 1QJIA 4G9LA 1A85A 1XFVA 3MA2A 5BOYA 5D3CA 4GR3A 1UTTA 4JIJA 2E3XA 1MMRA 1G49A 2WOAA 4FXYP 3F1AA 1DTHA 1ZS0A 3ZVSA 4ON1A 4CTHA 2O3EA 1BUDA 3TT4A 3LMCA 1FM1A 2WO8A 3CKIA 2CKIA 3DSLA 1OO9A 5I4OA 4ILWD 1ZTQA 3LE9A 4H84A 1QIBA 3ELMA 1GE7A 1G12A 3LILA 5CUHA 3SHIA 2JIHA 1R1JA 4WK7A 4WZVA 2OZRA 1YCMA 1SMPA 4JQGA 3HDBA 1KUGA 3LEAA 4FVLA 3TS4A 1GKDA 1BQQM 3O2XA 5D7WA 4GF1A 1JIZA 2TCLA 2W13A 1R54A 1G9KA 3BA0A 1BKCE 5D1TA 1HTDA 1FLSA 1JIWP 1ROSA 1XURA 4R3VA 1C3IA 3N2VA 3DPFA 3LJGA 4HX3A 1K7GA 1UTZA 1B3DA 1Y93A 1HV5A 4PKSA
chains in the Genus database with same CATH superfamily
4EFSA 4XM6A 1CGLA 4A7BA 2JSDA 1HY7A 1UEAA 1AKLA 4GUYA 2HU6A 5H8XA 1XFUA 1XFYA 4FXQA 2RJQA 1SLNA 4H76A 3LJZA 3TVCA 3I7IA 4H82A 2D1OA 1FBLA 1D8FA 5I43A 4I35A 2A8HA 1CQRA 2O36A 2K9CA 5JMYA 1XAXA 1EUBA 3DTKA 2OXUA 3N2UA 2L0RA 2RJPA 1C7KA 2XS4A 1J7NA 5L79A 2X7MA 3TSKA 1GO7P 5B5PA 1EB6A 2D1NA 2DW1A 2JT5A 1MMPA 2MLRA 2DDYA 3UVCA 3ZXHA 1RM8A 4H49A 2X3AA 2OVXA 3KECA 1JJ9A 3Q2GA 2XS3A 2MLSA 4PKUA 4GWMA 4WKIA 3LGPA 1BQOA 1CXVA 1SU3A 2X3CA 1B8YA 1ATLA 1H71P 1BKCI 3EHYA 3ZUKA 3G42A 1KBCA 1BSWA 1OM6A 5I12A 2J0TA 4QKZA 4JPAA 4IUWA 2OW2A 1AF0A 4AIGA 4AXQA 1PWUA 2DW0A 3EWJA 1I1IP 1AYKA 3EDGA 4XM8A 1DMTA 4GWNA 1CK7A 2W14A 1OS2A 1YQYA 1ND1A 2W0DA 3EDHA 1GXDA 4H30A 3B92A 1CGFA 1CAQA 4XBHA 2OI0A 5LABA 1IAGA 3DNGA 4G0DA 3V96B 1D8MA 3HBUP 1L6JA 2YB9A 5I0LA 3RTSA 3L0TA 2Y6CA 5D1SA 3KEKA 4DF9A 1Q3AA 1RMZA 4AYKA 4PKRA 1KUHA 3DL1A 2FV9A 4H3XA 1SLMA 2OW0A 3EDIA 1IACA 3OHOA 4DV8A 3VTGA 2DDFA 4WF6A 5I3MA 3L0VA 4L63A 2EROA 3P24A 3F17A 4PKWA 1MNCA 4H2EA 1PWWA 3GBOA 3HY9A 3VI1A 1MMQA 1BIWA 1I73A 4GR0A 3DWBA 1XUCA 1OM8A 5BOTA 5D2BA 3DTEA 456CA 2JNPA 2FV5A 4Q1LA 3NX7A 1GE6A 1JAQA 3LK8A 4XM7A 1Z3JA 3LJTA 3G5CA 1YOUA 3HDAP 1O0QA 3B8ZA 1JAOA 3KRYA 1JH1A 3DPEA 5D1UA 2PJTA 1GE5A 1ZVXA 3KMEA 2ERPA 2W12A 4A3WA 1IAAA 1S4BP 3LUMA 4L6TA 3LUNA 5I2ZA 1C8TA 3K7NA 4GR8A 2YIGA 4PKQA 1ZXCA 2OXWA 3U1RA 2WO9A 3Q2HA 5L7FA 1QIAA 1OM7A 3AYUA 3HYGA 3KHIA 2AIGP 1OMJA 1CIZA 1K7IA 1OS9A 1UMTA 1WNIA 830CA 3AYKA 4DD8A 2OW9A 3KEJA 3OHLA 4JA1A 2KRJA 3RTTA 3WV2A 1O0TA 3LIRA 2E2DA 1XFZA 3E8RA 1JANA 1PWVA 2Y6DA 3EHXA 2QPJA 4IN9A 3HB2P 1XFWA 3EDZA 1BUVM 2POJA 4JP4A 1SRPA 1G05A 1KAPP 1GO8P 3AIGA 3K7LA 1I76A 1IAEA 2CLTA 3WV3A 5CXAA 2I47A 4I03A 3KWVC 1KUKA 3I7GA 4L19A 1XM5A 1Y0VA 966CA 1JAPA 3KMCA 3WV1A 2OY2A 1QICA 4J4MA 1XUDA 3LKAA 1KUFA 1G4KA 3LQBA 4AUOA 3P1VA 1D5JA 3F19A 3LIKA 4FU4A 1ZP5A 3HBVP 1R1HA 4XCTA 1HOVA 1K7QA 4L7AA 1HFSA 1PWQA 1JK3A 4IJOA 2OVZA 3F16A 4GQLA 1IABA 1MMBA 3B2ZA 2J83A 4PKTA 4PKVA 2DW2A 2OXZA 1OZ9A 2MZHA 1CGEA 2V4BA 3F15A 4H1QA 2N8RA 3HY7A 3USNA 1IADA 3F18A 1QUAA 1Y8JA 2MZEA 1XFXA 3LQ0A 2W15A 1HFCA 4HMAA 3O64A 1UMSA 2OW1A 2ERQA 1SATA 4ZR5A 1BZSA 2SRTA 4WKEA 1GKCA 5B5OA 1BM6A 1PWPA 1QJJA 2MZIA 5CZMA 1KUIA 1D7XA 2JT6A 1R55A 4DPEA 1USNA 5BPAA 1JKYA 1EAKA 1ASTA 3DTIA 2OY4A 2Z2DA 1R1IA 1ZXVA 1YP1A 2K2GA 2X3BA 2AYKA 2USNA 1BKCA 1A86A 1QJIA 4G9LA 2YUFA 1A85A 1XFVA 3MA2A 5BOYA 5D3CA 4GR3A 1UTTA 4JIJA 2E3XA 1MMRA 1G49A 2WOAA 4FXYP 3F1AA 1DTHA 1ZS0A 3ZVSA 4ON1A 4CTHA 2O3EA 1BUDA 3TT4A 3LMCA 1FM1A 2WO8A 3CKIA 1TVIA 2CKIA 3DSLA 1OO9A 5I4OA 4ILWD 1ZTQA 3LE9A 4H84A 1QIBA 3ELMA 1GE7A 1G12A 3LILA 5CUHA 3SHIA 2JIHA 1R1JA 4WK7A 4WZVA 2OZRA 1YCMA 1SMPA 4JQGA 3HDBA 1KUGA 3LEAA 4FVLA 3TS4A 1GKDA 1BQQM 3O2XA 5D7WA 4GF1A 1JIZA 2TCLA 2W13A 1R54A 1G9KA 3BA0A 1BKCE 5D1TA 1HTDA 1FLSA 1JIWP 1ROSA 1XURA 4R3VA 1C3IA 3N2VA 3DPFA 3LJGA 4HX3A 1K7GA 1UTZA 1B3DA 1Y93A 1HV5A 4PKSA
chains in the Genus database with same CATH topology
4EFSA 4XM6A 1CGLA 4A7BA 2JSDA 1HY7A 1UEAA 1AKLA 4GUYA 2HU6A 5H8XA 1XFUA 1XFYA 4FXQA 2RJQA 1SLNA 4H76A 3LJZA 3TVCA 3I7IA 4H82A 2D1OA 1FBLA 1D8FA 5I43A 4I35A 2A8HA 1CQRA 2O36A 2K9CA 5JMYA 1EUBA 3DTKA 2OXUA 3N2UA 2L0RA 2RJPA 1C7KA 2XS4A 1J7NA 5L79A 2X7MA 3TSKA 1GO7P 5B5PA 1EB6A 2D1NA 2DW1A 2JT5A 1MMPA 2MLRA 2DDYA 3UVCA 3ZXHA 1RM8A 4H49A 2X3AA 2OVXA 3KECA 1JJ9A 3Q2GA 2XS3A 2MLSA 4PKUA 4GWMA 4WKIA 3LGPA 1BQOA 1CXVA 1SU3A 2X3CA 1B8YA 1ATLA 1H71P 1BKCI 3EHYA 3ZUKA 3G42A 1KBCA 1BSWA 1OM6A 5I12A 2J0TA 4QKZA 4JPAA 4IUWA 2OW2A 1AF0A 4AIGA 4AXQA 1PWUA 2DW0A 3EWJA 1I1IP 1AYKA 3EDGA 4XM8A 1DMTA 4GWNA 1CK7A 2W14A 1OS2A 1YQYA 1ND1A 2W0DA 3EDHA 1GXDA 4H30A 3B92A 1CGFA 1CAQA 4XBHA 2OI0A 5LABA 1IAGA 3DNGA 4G0DA 3V96B 1D8MA 3HBUP 1L6JA 2YB9A 5I0LA 3RTSA 3L0TA 2Y6CA 5D1SA 3KEKA 4DF9A 1Q3AA 1RMZA 4AYKA 4PKRA 1KUHA 3DL1A 2FV9A 4H3XA 1SLMA 2OW0A 3EDIA 1IACA 3OHOA 4DV8A 3VTGA 2DDFA 4WF6A 5I3MA 3L0VA 4L63A 2EROA 3P24A 3F17A 4PKWA 1MNCA 4H2EA 1PWWA 3GBOA 3HY9A 3VI1A 1MMQA 1BIWA 1I73A 4GR0A 3DWBA 1XUCA 1OM8A 5BOTA 5D2BA 3DTEA 456CA 2JNPA 2FV5A 4Q1LA 3NX7A 1GE6A 1JAQA 3LK8A 4XM7A 1Z3JA 3LJTA 3G5CA 1YOUA 3HDAP 1O0QA 3B8ZA 1JAOA 3KRYA 1JH1A 3DPEA 5D1UA 2PJTA 1GE5A 1ZVXA 3KMEA 2ERPA 2W12A 4A3WA 1IAAA 1S4BP 3LUMA 4L6TA 3LUNA 5I2ZA 1C8TA 3K7NA 4GR8A 2YIGA 4PKQA 1ZXCA 2OXWA 3U1RA 2WO9A 3Q2HA 5L7FA 1QIAA 1OM7A 3AYUA 3HYGA 3KHIA 2AIGP 1OMJA 1CIZA 1K7IA 1OS9A 1UMTA 1WNIA 830CA 3AYKA 4DD8A 2OW9A 3KEJA 3OHLA 4JA1A 2KRJA 3RTTA 3WV2A 1O0TA 3LIRA 2E2DA 1XFZA 3E8RA 1JANA 1PWVA 2Y6DA 3EHXA 2QPJA 4IN9A 3HB2P 1XFWA 3EDZA 1BUVM 2POJA 4JP4A 1SRPA 1G05A 1KAPP 1GO8P 3AIGA 3K7LA 1I76A 1IAEA 2CLTA 3WV3A 5CXAA 2I47A 4I03A 3KWVC 1KUKA 3I7GA 4L19A 1Y0VA 966CA 1JAPA 3KMCA 3WV1A 2OY2A 1QICA 4J4MA 1XUDA 3LKAA 1KUFA 1G4KA 3LQBA 4AUOA 3P1VA 1D5JA 3F19A 3LIKA 4FU4A 1ZP5A 3HBVP 1R1HA 4XCTA 1HOVA 1K7QA 4L7AA 1HFSA 1PWQA 1JK3A 4IJOA 2OVZA 3F16A 4GQLA 1IABA 1MMBA 3B2ZA 2J83A 4PKTA 4PKVA 2DW2A 2OXZA 2MZHA 1CGEA 2V4BA 3F15A 4H1QA 2N8RA 3HY7A 3USNA 1IADA 3F18A 1QUAA 1Y8JA 2MZEA 1XFXA 3LQ0A 2W15A 1HFCA 4HMAA 3O64A 1UMSA 2OW1A 2ERQA 1SATA 4ZR5A 1BZSA 2SRTA 4WKEA 1GKCA 5B5OA 1BM6A 1PWPA 1QJJA 2MZIA 5CZMA 1KUIA 1D7XA 2JT6A 1R55A 4DPEA 1USNA 5BPAA 1JKYA 1EAKA 1ASTA 3DTIA 2OY4A 2Z2DA 1R1IA 1ZXVA 1YP1A 2K2GA 2X3BA 2AYKA 2USNA 1BKCA 1A86A 1QJIA 4G9LA 2YUFA 1A85A 1XFVA 3MA2A 5BOYA 5D3CA 4GR3A 1UTTA 4JIJA 2E3XA 1MMRA 1G49A 2WOAA 4FXYP 3F1AA 1DTHA 1ZS0A 3ZVSA 4ON1A 4CTHA 2O3EA 1BUDA 3TT4A 3LMCA 1FM1A 2WO8A 3CKIA 2CKIA 3DSLA 1OO9A 5I4OA 4ILWD 1ZTQA 3LE9A 4H84A 1QIBA 3ELMA 1GE7A 1G12A 3LILA 5CUHA 3SHIA 2JIHA 1R1JA 4WK7A 4WZVA 2OZRA 1YCMA 1SMPA 4JQGA 3HDBA 1KUGA 3LEAA 4FVLA 3TS4A 1GKDA 1BQQM 3O2XA 5D7WA 4GF1A 1JIZA 2TCLA 2W13A 1R54A 1G9KA 3BA0A 1BKCE 5D1TA 1HTDA 1FLSA 1JIWP 1ROSA 1XURA 4R3VA 1C3IA 3N2VA 3DPFA 3LJGA 4HX3A 1K7GA 1UTZA 1B3DA 1Y93A 1HV5A 4PKSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EFS A;  4XM6 A;  1CGL A;  4A7B A;  2JSD A;  1HY7 A;  1UEA A;  1AKL A;  4GUY A;  2HU6 A;  5H8X A;  1XFU A;  1XFY A;  4FXQ A;  2RJQ A;  1SLN A;  4H76 A;  3LJZ A;  3TVC A;  3I7I A;  4H82 A;  2D1O A;  1FBL A;  1D8F A;  5I43 A;  4I35 A;  2A8H A;  1CQR A;  2O36 A;  2K9C A;  5JMY A;  1EUB A;  2OXU A;  3N2U A;  2L0R A;  2RJP A;  1C7K A;  2XS4 A;  1J7N A;  5L79 A;  2X7M A;  3TSK A;  1GO7 P;  5B5P A;  1EB6 A;  2D1N A;  2DW1 A;  2JT5 A;  1MMP A;  2MLR A;  2DDY A;  3UVC A;  3ZXH A;  1RM8 A;  4H49 A;  2X3A A;  2OVX A;  3KEC A;  1JJ9 A;  3Q2G A;  2XS3 A;  2MLS A;  4PKU A;  4GWM A;  4WKI A;  3LGP A;  1BQO A;  1CXV A;  1SU3 A;  2X3C A;  1B8Y A;  1ATL A;  1H71 P;  1BKC I;  3EHY A;  3ZUK A;  3G42 A;  1KBC A;  1BSW A;  1OM6 A;  5I12 A;  2J0T A;  4QKZ A;  4JPA A;  4IUW A;  2OW2 A;  1AF0 A;  4AIG A;  4AXQ A;  1PWU A;  2DW0 A;  3EWJ A;  1I1I P;  1AYK A;  3EDG A;  4XM8 A;  1DMT A;  4GWN A;  1CK7 A;  2W14 A;  1OS2 A;  1YQY A;  1ND1 A;  2W0D A;  3EDH A;  1GXD A;  4H30 A;  3B92 A;  1CGF A;  1CAQ A;  4XBH A;  2OI0 A;  5LAB A;  1IAG A;  3DNG A;  4G0D A;  3V96 B;  1D8M A;  3HBU P;  1L6J A;  2YB9 A;  5I0L A;  3RTS A;  3L0T A;  2Y6C A;  5D1S A;  3KEK A;  4DF9 A;  1Q3A A;  1RMZ A;  4AYK A;  4PKR A;  1KUH A;  3DL1 A;  2FV9 A;  4H3X A;  1SLM A;  2OW0 A;  3EDI A;  1IAC A;  3OHO A;  4DV8 A;  3VTG A;  2DDF A;  4WF6 A;  5I3M A;  3L0V A;  4L63 A;  2ERO A;  3P24 A;  3F17 A;  4PKW A;  1MNC A;  4H2E A;  1PWW A;  3GBO A;  3HY9 A;  3VI1 A;  1MMQ A;  1BIW A;  1I73 A;  4GR0 A;  3DWB A;  1XUC A;  1OM8 A;  5BOT A;  5D2B A;  456C A;  2JNP A;  2FV5 A;  4Q1L A;  3NX7 A;  1GE6 A;  1JAQ A;  3LK8 A;  4XM7 A;  1Z3J A;  3LJT A;  3G5C A;  1YOU A;  3HDA P;  1O0Q A;  3B8Z A;  1JAO A;  3KRY A;  1JH1 A;  3DPE A;  5D1U A;  2PJT A;  1GE5 A;  1ZVX A;  3KME A;  2ERP A;  2W12 A;  4A3W A;  1IAA A;  1S4B P;  3LUM A;  4L6T A;  3LUN A;  5I2Z A;  1C8T A;  3K7N A;  4GR8 A;  2YIG A;  4PKQ A;  1ZXC A;  2OXW A;  3U1R A;  2WO9 A;  3Q2H A;  5L7F A;  1QIA A;  1OM7 A;  3AYU A;  3HYG A;  3KHI A;  2AIG P;  1OMJ A;  1CIZ A;  1K7I A;  1OS9 A;  1UMT A;  1WNI A;  830C A;  3AYK A;  4DD8 A;  2OW9 A;  3KEJ A;  3OHL A;  4JA1 A;  2KRJ A;  3RTT A;  3WV2 A;  1O0T A;  3LIR A;  2E2D A;  1XFZ A;  3E8R A;  1JAN A;  1PWV A;  2Y6D A;  3EHX A;  2QPJ A;  4IN9 A;  3HB2 P;  1XFW A;  3EDZ A;  1BUV M;  2POJ A;  4JP4 A;  1SRP A;  1G05 A;  1KAP P;  1GO8 P;  3AIG A;  3K7L A;  1I76 A;  1IAE A;  2CLT A;  3WV3 A;  5CXA A;  2I47 A;  4I03 A;  3KWV C;  1KUK A;  3I7G A;  4L19 A;  1Y0V A;  966C A;  1JAP A;  3KMC A;  3WV1 A;  2OY2 A;  1QIC A;  4J4M A;  1XUD A;  3LKA A;  1KUF A;  1G4K A;  3LQB A;  4AUO A;  3P1V A;  1D5J A;  3F19 A;  3LIK A;  4FU4 A;  1ZP5 A;  3HBV P;  1R1H A;  4XCT A;  1HOV A;  1K7Q A;  1HFS A;  1PWQ A;  1JK3 A;  4IJO A;  2OVZ A;  3F16 A;  4GQL A;  1IAB A;  1MMB A;  3B2Z A;  2J83 A;  4PKT A;  4PKV A;  2DW2 A;  2OXZ A;  2MZH A;  1CGE A;  2V4B A;  3F15 A;  4H1Q A;  2N8R A;  3HY7 A;  3USN A;  1IAD A;  3F18 A;  1QUA A;  1Y8J A;  2MZE A;  1XFX A;  3LQ0 A;  2W15 A;  1HFC A;  4HMA A;  3O64 A;  1UMS A;  2OW1 A;  2ERQ A;  1SAT A;  4ZR5 A;  1BZS A;  2SRT A;  4WKE A;  1GKC A;  5B5O A;  1BM6 A;  1PWP A;  1QJJ A;  2MZI A;  5CZM A;  1KUI A;  1D7X A;  2JT6 A;  1R55 A;  4DPE A;  1USN A;  5BPA A;  1JKY A;  1EAK A;  1AST A;  2OY4 A;  2Z2D A;  1R1I A;  1ZXV A;  1YP1 A;  2K2G A;  2X3B A;  2AYK A;  2USN A;  1BKC A;  1A86 A;  1QJI A;  4G9L A;  1A85 A;  1XFV A;  3MA2 A;  5BOY A;  5D3C A;  4GR3 A;  1UTT A;  4JIJ A;  2E3X A;  1MMR A;  1G49 A;  2WOA A;  4FXY P;  3F1A A;  1DTH A;  1ZS0 A;  3ZVS A;  4ON1 A;  4CTH A;  2O3E A;  1BUD A;  3TT4 A;  3LMC A;  1FM1 A;  2WO8 A;  3CKI A;  2CKI A;  3DSL A;  1OO9 A;  5I4O A;  4ILW D;  1ZTQ A;  3LE9 A;  4H84 A;  1QIB A;  3ELM A;  1GE7 A;  1G12 A;  3LIL A;  5CUH A;  3SHI A;  2JIH A;  1R1J A;  4WK7 A;  4WZV A;  2OZR A;  1YCM A;  1SMP A;  4JQG A;  3HDB A;  1KUG A;  3LEA A;  4FVL A;  3TS4 A;  1GKD A;  1BQQ M;  3O2X A;  5D7W A;  4GF1 A;  1JIZ A;  2TCL A;  2W13 A;  1R54 A;  1G9K A;  3BA0 A;  1BKC E;  5D1T A;  1HTD A;  1FLS A;  1JIW P;  1ROS A;  1XUR A;  4R3V A;  1C3I A;  3N2V A;  3DPF A;  3LJG A;  4HX3 A;  1K7G A;  1UTZ A;  1B3D A;  1Y93 A;  1HV5 A;  4PKS A; 
#chains in the Genus database with same CATH topology
 4EFS A;  4XM6 A;  1CGL A;  4A7B A;  2JSD A;  1HY7 A;  1UEA A;  1AKL A;  4GUY A;  2HU6 A;  5H8X A;  1XFU A;  1XFY A;  4FXQ A;  2RJQ A;  1SLN A;  4H76 A;  3LJZ A;  3TVC A;  3I7I A;  4H82 A;  2D1O A;  1FBL A;  1D8F A;  5I43 A;  4I35 A;  2A8H A;  1CQR A;  2O36 A;  2K9C A;  5JMY A;  1XAX A;  1EUB A;  3DTK A;  2OXU A;  3N2U A;  2L0R A;  2RJP A;  1C7K A;  2XS4 A;  1J7N A;  5L79 A;  2X7M A;  3TSK A;  1GO7 P;  5B5P A;  1EB6 A;  2D1N A;  2DW1 A;  2JT5 A;  1MMP A;  2MLR A;  2DDY A;  3UVC A;  3ZXH A;  1RM8 A;  4H49 A;  2X3A A;  2OVX A;  3KEC A;  1JJ9 A;  3Q2G A;  2XS3 A;  2MLS A;  4PKU A;  4GWM A;  4WKI A;  3LGP A;  1BQO A;  1CXV A;  1SU3 A;  2X3C A;  1B8Y A;  1ATL A;  1H71 P;  1BKC I;  3EHY A;  3ZUK A;  3G42 A;  1KBC A;  1BSW A;  1OM6 A;  5I12 A;  2J0T A;  4QKZ A;  4JPA A;  4IUW A;  2OW2 A;  1AF0 A;  4AIG A;  4AXQ A;  1PWU A;  2DW0 A;  3EWJ A;  1I1I P;  1AYK A;  3EDG A;  4XM8 A;  1DMT A;  4GWN A;  1CK7 A;  2W14 A;  1OS2 A;  1YQY A;  1ND1 A;  2W0D A;  3EDH A;  1GXD A;  4H30 A;  3B92 A;  1CGF A;  1CAQ A;  4XBH A;  2OI0 A;  5LAB A;  1IAG A;  3DNG A;  4G0D A;  3V96 B;  1D8M A;  3HBU P;  1L6J A;  2YB9 A;  5I0L A;  3RTS A;  3L0T A;  2Y6C A;  5D1S A;  3KEK A;  4DF9 A;  1Q3A A;  1RMZ A;  4AYK A;  4PKR A;  1KUH A;  3DL1 A;  2FV9 A;  4H3X A;  1SLM A;  2OW0 A;  3EDI A;  1IAC A;  3OHO A;  4DV8 A;  3VTG A;  2DDF A;  4WF6 A;  5I3M A;  3L0V A;  4L63 A;  2ERO A;  3P24 A;  3F17 A;  4PKW A;  1MNC A;  4H2E A;  1PWW A;  3GBO A;  3HY9 A;  3VI1 A;  1MMQ A;  1BIW A;  1I73 A;  4GR0 A;  3DWB A;  1XUC A;  1OM8 A;  5BOT A;  5D2B A;  3DTE A;  456C A;  2JNP A;  2FV5 A;  4Q1L A;  3NX7 A;  1GE6 A;  1JAQ A;  3LK8 A;  4XM7 A;  1Z3J A;  3LJT A;  3G5C A;  1YOU A;  3HDA P;  1O0Q A;  3B8Z A;  1JAO A;  3KRY A;  1JH1 A;  3DPE A;  5D1U A;  2PJT A;  1GE5 A;  1ZVX A;  3KME A;  2ERP A;  2W12 A;  4A3W A;  1IAA A;  1S4B P;  3LUM A;  4L6T A;  3LUN A;  5I2Z A;  1C8T A;  3K7N A;  4GR8 A;  2YIG A;  4PKQ A;  1ZXC A;  2OXW A;  3U1R A;  2WO9 A;  3Q2H A;  5L7F A;  1QIA A;  1OM7 A;  3AYU A;  3HYG A;  3KHI A;  2AIG P;  1OMJ A;  1CIZ A;  1K7I A;  1OS9 A;  1UMT A;  1WNI A;  830C A;  3AYK A;  4DD8 A;  2OW9 A;  3KEJ A;  3OHL A;  4JA1 A;  2KRJ A;  3RTT A;  3WV2 A;  1O0T A;  3LIR A;  2E2D A;  1XFZ A;  3E8R A;  1JAN A;  1PWV A;  2Y6D A;  3EHX A;  2QPJ A;  4IN9 A;  3HB2 P;  1XFW A;  3EDZ A;  1BUV M;  2POJ A;  4JP4 A;  1SRP A;  1G05 A;  1KAP P;  1GO8 P;  3AIG A;  3K7L A;  1I76 A;  1IAE A;  2CLT A;  3WV3 A;  5CXA A;  2I47 A;  4I03 A;  3KWV C;  1KUK A;  3I7G A;  4L19 A;  1XM5 A;  1Y0V A;  966C A;  1JAP A;  3KMC A;  3WV1 A;  2OY2 A;  1QIC A;  4J4M A;  1XUD A;  3LKA A;  1KUF A;  1G4K A;  3LQB A;  4AUO A;  3P1V A;  1D5J A;  3F19 A;  3LIK A;  4FU4 A;  1ZP5 A;  3HBV P;  1R1H A;  4XCT A;  1HOV A;  1K7Q A;  4L7A A;  1HFS A;  1PWQ A;  1JK3 A;  4IJO A;  2OVZ A;  3F16 A;  4GQL A;  1IAB A;  1MMB A;  3B2Z A;  2J83 A;  4PKT A;  4PKV A;  2DW2 A;  2OXZ A;  1OZ9 A;  2MZH A;  1CGE A;  2V4B A;  3F15 A;  4H1Q A;  2N8R A;  3HY7 A;  3USN A;  1IAD A;  3F18 A;  1QUA A;  1Y8J A;  2MZE A;  1XFX A;  3LQ0 A;  2W15 A;  1HFC A;  4HMA A;  3O64 A;  1UMS A;  2OW1 A;  2ERQ A;  1SAT A;  4ZR5 A;  1BZS A;  2SRT A;  4WKE A;  1GKC A;  5B5O A;  1BM6 A;  1PWP A;  1QJJ A;  2MZI A;  5CZM A;  1KUI A;  1D7X A;  2JT6 A;  1R55 A;  4DPE A;  1USN A;  5BPA A;  1JKY A;  1EAK A;  1AST A;  3DTI A;  2OY4 A;  2Z2D A;  1R1I A;  1ZXV A;  1YP1 A;  2K2G A;  2X3B A;  2AYK A;  2USN A;  1BKC A;  1A86 A;  1QJI A;  4G9L A;  2YUF A;  1A85 A;  1XFV A;  3MA2 A;  5BOY A;  5D3C A;  4GR3 A;  1UTT A;  4JIJ A;  2E3X A;  1MMR A;  1G49 A;  2WOA A;  4FXY P;  3F1A A;  1DTH A;  1ZS0 A;  3ZVS A;  4ON1 A;  4CTH A;  2O3E A;  1BUD A;  3TT4 A;  3LMC A;  1FM1 A;  2WO8 A;  3CKI A;  1TVI A;  2CKI A;  3DSL A;  1OO9 A;  5I4O A;  4ILW D;  1ZTQ A;  3LE9 A;  4H84 A;  1QIB A;  3ELM A;  1GE7 A;  1G12 A;  3LIL A;  5CUH A;  3SHI A;  2JIH A;  1R1J A;  4WK7 A;  4WZV A;  2OZR A;  1YCM A;  1SMP A;  4JQG A;  3HDB A;  1KUG A;  3LEA A;  4FVL A;  3TS4 A;  1GKD A;  1BQQ M;  3O2X A;  5D7W A;  4GF1 A;  1JIZ A;  2TCL A;  2W13 A;  1R54 A;  1G9K A;  3BA0 A;  1BKC E;  5D1T A;  1HTD A;  1FLS A;  1JIW P;  1ROS A;  1XUR A;  4R3V A;  1C3I A;  3N2V A;  3DPF A;  3LJG A;  4HX3 A;  1K7G A;  1UTZ A;  1B3D A;  1Y93 A;  1HV5 A;  4PKS A; 
#chains in the Genus database with same CATH homology
 4EFS A;  4XM6 A;  1CGL A;  4A7B A;  2JSD A;  1HY7 A;  1UEA A;  1AKL A;  4GUY A;  2HU6 A;  5H8X A;  1XFU A;  1XFY A;  4FXQ A;  2RJQ A;  1SLN A;  4H76 A;  3LJZ A;  3TVC A;  3I7I A;  4H82 A;  2D1O A;  1FBL A;  1D8F A;  5I43 A;  4I35 A;  2A8H A;  1CQR A;  2O36 A;  2K9C A;  5JMY A;  1EUB A;  3DTK A;  2OXU A;  3N2U A;  2L0R A;  2RJP A;  1C7K A;  2XS4 A;  1J7N A;  5L79 A;  2X7M A;  3TSK A;  1GO7 P;  5B5P A;  1EB6 A;  2D1N A;  2DW1 A;  2JT5 A;  1MMP A;  2MLR A;  2DDY A;  3UVC A;  3ZXH A;  1RM8 A;  4H49 A;  2X3A A;  2OVX A;  3KEC A;  1JJ9 A;  3Q2G A;  2XS3 A;  2MLS A;  4PKU A;  4GWM A;  4WKI A;  3LGP A;  1BQO A;  1CXV A;  1SU3 A;  2X3C A;  1B8Y A;  1ATL A;  1H71 P;  1BKC I;  3EHY A;  3ZUK A;  3G42 A;  1KBC A;  1BSW A;  1OM6 A;  5I12 A;  2J0T A;  4QKZ A;  4JPA A;  4IUW A;  2OW2 A;  1AF0 A;  4AIG A;  4AXQ A;  1PWU A;  2DW0 A;  3EWJ A;  1I1I P;  1AYK A;  3EDG A;  4XM8 A;  1DMT A;  4GWN A;  1CK7 A;  2W14 A;  1OS2 A;  1YQY A;  1ND1 A;  2W0D A;  3EDH A;  1GXD A;  4H30 A;  3B92 A;  1CGF A;  1CAQ A;  4XBH A;  2OI0 A;  5LAB A;  1IAG A;  3DNG A;  4G0D A;  3V96 B;  1D8M A;  3HBU P;  1L6J A;  2YB9 A;  5I0L A;  3RTS A;  3L0T A;  2Y6C A;  5D1S A;  3KEK A;  4DF9 A;  1Q3A A;  1RMZ A;  4AYK A;  4PKR A;  1KUH A;  3DL1 A;  2FV9 A;  4H3X A;  1SLM A;  2OW0 A;  3EDI A;  1IAC A;  3OHO A;  4DV8 A;  3VTG A;  2DDF A;  4WF6 A;  5I3M A;  3L0V A;  4L63 A;  2ERO A;  3P24 A;  3F17 A;  4PKW A;  1MNC A;  4H2E A;  1PWW A;  3GBO A;  3HY9 A;  3VI1 A;  1MMQ A;  1BIW A;  1I73 A;  4GR0 A;  3DWB A;  1XUC A;  1OM8 A;  5BOT A;  5D2B A;  3DTE A;  456C A;  2JNP A;  2FV5 A;  4Q1L A;  3NX7 A;  1GE6 A;  1JAQ A;  3LK8 A;  4XM7 A;  1Z3J A;  3LJT A;  3G5C A;  1YOU A;  3HDA P;  1O0Q A;  3B8Z A;  1JAO A;  3KRY A;  1JH1 A;  3DPE A;  5D1U A;  2PJT A;  1GE5 A;  1ZVX A;  3KME A;  2ERP A;  2W12 A;  4A3W A;  1IAA A;  1S4B P;  3LUM A;  4L6T A;  3LUN A;  5I2Z A;  1C8T A;  3K7N A;  4GR8 A;  2YIG A;  4PKQ A;  1ZXC A;  2OXW A;  3U1R A;  2WO9 A;  3Q2H A;  5L7F A;  1QIA A;  1OM7 A;  3AYU A;  3HYG A;  3KHI A;  2AIG P;  1OMJ A;  1CIZ A;  1K7I A;  1OS9 A;  1UMT A;  1WNI A;  830C A;  3AYK A;  4DD8 A;  2OW9 A;  3KEJ A;  3OHL A;  4JA1 A;  2KRJ A;  3RTT A;  3WV2 A;  1O0T A;  3LIR A;  2E2D A;  1XFZ A;  3E8R A;  1JAN A;  1PWV A;  2Y6D A;  3EHX A;  2QPJ A;  4IN9 A;  3HB2 P;  1XFW A;  3EDZ A;  1BUV M;  2POJ A;  4JP4 A;  1SRP A;  1G05 A;  1KAP P;  1GO8 P;  3AIG A;  3K7L A;  1I76 A;  1IAE A;  2CLT A;  3WV3 A;  5CXA A;  2I47 A;  4I03 A;  3KWV C;  1KUK A;  3I7G A;  4L19 A;  1Y0V A;  966C A;  1JAP A;  3KMC A;  3WV1 A;  2OY2 A;  1QIC A;  4J4M A;  1XUD A;  3LKA A;  1KUF A;  1G4K A;  3LQB A;  4AUO A;  3P1V A;  1D5J A;  3F19 A;  3LIK A;  4FU4 A;  1ZP5 A;  3HBV P;  1R1H A;  4XCT A;  1HOV A;  1K7Q A;  4L7A A;  1HFS A;  1PWQ A;  1JK3 A;  4IJO A;  2OVZ A;  3F16 A;  4GQL A;  1IAB A;  1MMB A;  3B2Z A;  2J83 A;  4PKT A;  4PKV A;  2DW2 A;  2OXZ A;  2MZH A;  1CGE A;  2V4B A;  3F15 A;  4H1Q A;  2N8R A;  3HY7 A;  3USN A;  1IAD A;  3F18 A;  1QUA A;  1Y8J A;  2MZE A;  1XFX A;  3LQ0 A;  2W15 A;  1HFC A;  4HMA A;  3O64 A;  1UMS A;  2OW1 A;  2ERQ A;  1SAT A;  4ZR5 A;  1BZS A;  2SRT A;  4WKE A;  1GKC A;  5B5O A;  1BM6 A;  1PWP A;  1QJJ A;  2MZI A;  5CZM A;  1KUI A;  1D7X A;  2JT6 A;  1R55 A;  4DPE A;  1USN A;  5BPA A;  1JKY A;  1EAK A;  1AST A;  3DTI A;  2OY4 A;  2Z2D A;  1R1I A;  1ZXV A;  1YP1 A;  2K2G A;  2X3B A;  2AYK A;  2USN A;  1BKC A;  1A86 A;  1QJI A;  4G9L A;  2YUF A;  1A85 A;  1XFV A;  3MA2 A;  5BOY A;  5D3C A;  4GR3 A;  1UTT A;  4JIJ A;  2E3X A;  1MMR A;  1G49 A;  2WOA A;  4FXY P;  3F1A A;  1DTH A;  1ZS0 A;  3ZVS A;  4ON1 A;  4CTH A;  2O3E A;  1BUD A;  3TT4 A;  3LMC A;  1FM1 A;  2WO8 A;  3CKI A;  2CKI A;  3DSL A;  1OO9 A;  5I4O A;  4ILW D;  1ZTQ A;  3LE9 A;  4H84 A;  1QIB A;  3ELM A;  1GE7 A;  1G12 A;  3LIL A;  5CUH A;  3SHI A;  2JIH A;  1R1J A;  4WK7 A;  4WZV A;  2OZR A;  1YCM A;  1SMP A;  4JQG A;  3HDB A;  1KUG A;  3LEA A;  4FVL A;  3TS4 A;  1GKD A;  1BQQ M;  3O2X A;  5D7W A;  4GF1 A;  1JIZ A;  2TCL A;  2W13 A;  1R54 A;  1G9K A;  3BA0 A;  1BKC E;  5D1T A;  1HTD A;  1FLS A;  1JIW P;  1ROS A;  1XUR A;  4R3V A;  1C3I A;  3N2V A;  3DPF A;  3LJG A;  4HX3 A;  1K7G A;  1UTZ A;  1B3D A;  1Y93 A;  1HV5 A;  4PKS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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