1IACA

Refined 1.8 angstroms x-ray crystal structure of astacin, a zinc-endopeptidase from the crayfish astacus astacus l. structure determination, refinement, molecular structure and comparison with thermolysin
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
200
structure length
200
Chain Sequence
AAILGDEYLWSGGVIPYTFAGVSGADQSAILSGMQELEEKTCIRFVPRTTESDYVEIFTSGSGCWSYVGRISGAQQVSLQANGCVYHGTIIHELMHAIGFYHEHTRMDRDNYVTINYQNVDPSMTSNFDIDTYSRYVGEDYQYYSIMHYGKYSFSIQWGVLETIVPLQNGIDLTDPYDKAHMLQTDANQINNLYTNECSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Refined 1.8 A X-ray crystal structure of astacin, a zinc-endopeptidase from the crayfish Astacus astacus L. Structure determination, refinement, molecular structure and comparison with thermolysin.
pubmed doi rcsb
molecule tags Zinc endopeptidase
source organism Astacus astacus
molecule keywords ASTACIN
total genus 66
structure length 200
sequence length 200
ec nomenclature ec 3.4.24.21: Astacin.
pdb deposition date 1994-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01400 Astacin Astacin (Peptidase family M12A)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1iacA00
4CTHA 2TCLA 2K2GA 1KUGA 4XCTA 3LUNA 2L0RA 1I1IP 5L7FA 3LUMA 4H82A 2CLTA 5D1TA 3DPFA 1AF0A 1CXVA 1B3DA 3HBVP 966CA 1A85A 3GBOA 3VI1A 1GO8P 3HY7A 4QKZA 1XFYA 2V4BA 1R1IA 1XFUA 1XUDA 2MLSA 5D1SA 4GR3A 2DW2A 1I73A 830CA 1Y8JA 1IABA 456CA 3LJTA 3EDHA 2W12A 2CKIA 5B5OA 1SATA 2OXWA 3TSKA 3ZUKA 3P1VA 1HFCA 3HDBA 4FXYP 1QIAA 1FM1A 4PKWA 2OXUA 1BKCE 2DW1A 5BOYA 4J4MA 3L0VA 1IAGA 1JKYA 2QPJA 1YP1A 1C3IA 1CGEA 1OMJA 4R3VA 1XFZA 2KRJA 1YOUA 1PWQA 1SU3A 3KRYA 1OM7A 2OVZA 2D1NA 1L6JA 1S4BP 3K7LA 1K7IA 2OW9A 2OXZA 4GF1A 5CZMA 1GKCA 1ND1A 1BM6A 3LQ0A 1PWVA 1Y0VA 1ZP5A 1KBCA 1USNA 2ERQA 4DV8A 3HY9A 1XUCA 2J0TA 1IAEA 3KWVC 2USNA 2EROA 4GR0A 3NX7A 1R1JA 3LIKA 3KECA 4IJOA 3G5CA 3DNGA 2WO8A 1G05A 3K7NA 1UEAA 4A3WA 1UMTA 1SLMA 1BUDA 4AXQA 3AIGA 1JIWP 1IACA 1XFXA 1QJIA 1EAKA 2J83A 4FVLA 1RMZA 1I76A 1ZVXA 2RJPA 1ROSA 3EDGA 3F18A 3RTTA 1JJ9A 2O36A 3KEJA 1D8MA 1MNCA 4XM6A 1GKDA 1R1HA 2I47A 3LGPA 2HU6A 4FXQA 3O64A 5D1UA 1FLSA 4DPEA 4H49A 4PKVA 1OM6A 1JAQA 2OW2A 2DDYA 3OHOA 4JP4A 1SRPA 3KEKA 3F17A 2OW0A 1JAPA 2JT6A 2PJTA 3EWJA 4WK7A 1ZXCA 3LKAA 1Y93A 4G0DA 4ZR5A 5JMYA 3F19A 4H76A 1EB6A 4GR8A 1WNIA 2SRTA 4H2EA 2JSDA 1BUVM 1BQOA 4GQLA 1HV5A 3DL1A 3EHYA 2DW0A 3LIRA 2FV9A 5BOTA 1C8TA 1ATLA 3CKIA 1GE6A 2WO9A 3F15A 4ON1A 2RJQA 4XM8A 1CK7A 3ZXHA 1KUKA 2X3BA 4IUWA 1UTZA 1QICA 2AIGP 1XFWA 3TVCA 1QJJA 1D8FA 4AIGA 3AYUA 2XS3A 1XURA 3Q2HA 4HMAA 1G4KA 1MMPA 3HYGA 1HTDA 3B8ZA 5B5PA 3HBUP 2A8HA 3Q2GA 1DTHA 4JPAA 2W15A 4H84A 1ZTQA 3WV1A 5CUHA 1Z3JA 3N2VA 1MMRA 5H8XA 3U1RA 1PWWA 3MA2A 3BA0A 4PKUA 3V96B 1JK3A 5D7WA 4WKIA 3KMCA 1R55A 1JIZA 4IN9A 1BKCA 1O0QA 3P24A 3VTGA 2MLRA 3EDIA 2OVXA 2W0DA 1IAAA 2Z2DA 3LJZA 3LEAA 1ASTA 3OHLA 1K7GA 1YQYA 2OW1A 1SLNA 3B92A 1FBLA 2WOAA 4ILWD 3WV3A 4JA1A 5I4OA 1AYKA 4EFSA 5I2ZA 2DDFA 3WV2A 1JH1A 1PWUA 2OY4A 2YB9A 2FV5A 5BPAA 1EUBA 1GE5A 3HB2P 3LMCA 3LE9A 1H71P 1ZXVA 1K7QA 1BKCI 3TS4A 3USNA 1MMBA 4WKEA 1IADA 3B2ZA 3F16A 2E3XA 1BQQM 2YIGA 1OS2A 1OM8A 1SMPA 4PKQA 2OZRA 1UMSA 4L6TA 1KUFA 3LILA 3LQBA 4H1QA 2W13A 3I7GA 2Y6DA 5D2BA 4PKRA 2JT5A 2MZEA 4AUOA 4GWNA 5CXAA 2D1OA 3E8RA 5I43A 3N2UA 5D3CA 3L0TA 1OO9A 2OY2A 1KAPP 1CQRA 3O2XA 3F1AA 1DMTA 1ZS0A 3EHXA 2JNPA 1JAOA 2E2DA 4GWMA 4HX3A 1BIWA 1QUAA 4L63A 4FU4A 2W14A 2X3CA 3KMEA 1C7KA 1BZSA 1GO7P 1Q3AA 4I03A 3DWBA 3HDAP 2ERPA 4H3XA 3KHIA 3RTSA 2K9CA 1D7XA 1GE7A 1J7NA 5I3MA 3LJGA 4H30A 3TT4A 3I7IA 4L19A 4GUYA 1R54A 3ELMA 2X3AA 1HOVA 1KUIA 1CGFA 3ZVSA 2AYKA 2POJA 1YCMA 1GXDA 2X7MA 4WZVA 4DD8A 1MMQA 4JIJA 3LK8A 2N8RA 4Q1LA 1G12A 4JQGA 1OS9A 4A7BA 2JIHA 1QIBA 1D5JA 2MZHA 3EDZA 2XS4A 2Y6CA 3UVCA 5I0LA 5LABA 1KUHA 4I35A 1BSWA 3DPEA 2MZIA 3AYKA 1HY7A 2O3EA 4AYKA 3DSLA 1G9KA 2OI0A 1G49A 1HFSA 1CAQA 1CIZA 1CGLA 4PKTA 4DF9A 5L79A 1JANA 1XFVA 1B8YA 4XBHA 1PWPA 4XM7A 4PKSA 4G9LA 1RM8A 1A86A 4WF6A 1AKLA 1O0TA 3G42A 5I12A 3SHIA 1UTTA
chains in the Genus database with same CATH superfamily
4CTHA 2TCLA 2K2GA 1KUGA 4XCTA 3LUNA 2L0RA 1I1IP 5L7FA 3LUMA 4H82A 2CLTA 5D1TA 3DPFA 1AF0A 1CXVA 1B3DA 3HBVP 966CA 1A85A 3GBOA 3VI1A 1GO8P 3HY7A 4QKZA 1XFYA 2V4BA 1R1IA 1XFUA 1XUDA 2MLSA 5D1SA 4GR3A 2DW2A 1I73A 830CA 1Y8JA 1IABA 456CA 3LJTA 3EDHA 2W12A 2CKIA 5B5OA 1SATA 2OXWA 3TSKA 3ZUKA 3P1VA 1HFCA 3HDBA 4FXYP 1QIAA 1FM1A 4PKWA 2OXUA 1BKCE 2DW1A 5BOYA 4J4MA 3L0VA 1IAGA 1JKYA 2QPJA 1YP1A 1C3IA 1CGEA 1OMJA 4R3VA 1XFZA 2KRJA 1YOUA 1PWQA 1SU3A 3KRYA 1XM5A 1OM7A 2OVZA 2D1NA 1L6JA 1S4BP 3K7LA 1K7IA 2OW9A 2OXZA 4GF1A 5CZMA 1GKCA 1ND1A 1BM6A 2YUFA 3LQ0A 1PWVA 1Y0VA 1ZP5A 1KBCA 1USNA 2ERQA 4DV8A 3HY9A 1XUCA 2J0TA 1IAEA 3KWVC 2USNA 2EROA 4GR0A 3NX7A 1R1JA 3LIKA 3KECA 4IJOA 3G5CA 3DNGA 2WO8A 1G05A 3K7NA 1UEAA 1XAXA 4A3WA 1UMTA 1SLMA 1BUDA 4AXQA 3AIGA 1JIWP 1IACA 1XFXA 1QJIA 1EAKA 2J83A 4FVLA 1RMZA 1I76A 1ZVXA 2RJPA 1ROSA 3EDGA 3F18A 3RTTA 1JJ9A 2O36A 3KEJA 1D8MA 1MNCA 4XM6A 1GKDA 1R1HA 2I47A 3LGPA 2HU6A 4FXQA 3O64A 5D1UA 1FLSA 4DPEA 4H49A 4PKVA 1OM6A 1JAQA 2OW2A 2DDYA 3OHOA 4JP4A 1SRPA 3KEKA 3F17A 2OW0A 1JAPA 2JT6A 2PJTA 3EWJA 4WK7A 1ZXCA 3LKAA 1Y93A 4G0DA 4ZR5A 5JMYA 3F19A 4H76A 1EB6A 4GR8A 1WNIA 2SRTA 4H2EA 2JSDA 1BUVM 1BQOA 4GQLA 1HV5A 3DL1A 3EHYA 2DW0A 1OZ9A 3LIRA 2FV9A 5BOTA 1C8TA 1ATLA 3CKIA 1GE6A 2WO9A 3F15A 4ON1A 2RJQA 4XM8A 1CK7A 3ZXHA 1KUKA 2X3BA 4IUWA 1UTZA 1QICA 2AIGP 1XFWA 3TVCA 1QJJA 1D8FA 4AIGA 3AYUA 2XS3A 1XURA 3Q2HA 4HMAA 1G4KA 1MMPA 3HYGA 1HTDA 3B8ZA 5B5PA 3HBUP 2A8HA 3Q2GA 1DTHA 4JPAA 2W15A 4H84A 1ZTQA 3WV1A 5CUHA 1Z3JA 3N2VA 1MMRA 5H8XA 3U1RA 1PWWA 3MA2A 3BA0A 4PKUA 3V96B 1JK3A 5D7WA 4WKIA 3KMCA 1R55A 1JIZA 4IN9A 1BKCA 1O0QA 3P24A 3VTGA 2MLRA 3EDIA 2OVXA 2W0DA 1IAAA 2Z2DA 3LJZA 3LEAA 1ASTA 3OHLA 1K7GA 1YQYA 2OW1A 1SLNA 3B92A 1FBLA 2WOAA 4ILWD 3WV3A 4JA1A 5I4OA 1AYKA 4EFSA 5I2ZA 1TVIA 2DDFA 3WV2A 1JH1A 1PWUA 2OY4A 2YB9A 3DTEA 2FV5A 5BPAA 1EUBA 1GE5A 3HB2P 3LMCA 3LE9A 1H71P 1ZXVA 1K7QA 1BKCI 3TS4A 4L7AA 3USNA 1MMBA 4WKEA 1IADA 3B2ZA 3F16A 2E3XA 1BQQM 2YIGA 1OS2A 1OM8A 1SMPA 4PKQA 2OZRA 1UMSA 4L6TA 1KUFA 3LILA 3LQBA 4H1QA 2W13A 3I7GA 2Y6DA 5D2BA 4PKRA 2JT5A 2MZEA 4AUOA 4GWNA 5CXAA 2D1OA 3E8RA 5I43A 3N2UA 5D3CA 3L0TA 1OO9A 2OY2A 1KAPP 1CQRA 3O2XA 3F1AA 1DMTA 1ZS0A 3EHXA 2JNPA 1JAOA 2E2DA 3DTKA 4GWMA 4HX3A 1BIWA 1QUAA 4L63A 4FU4A 2W14A 2X3CA 3KMEA 1C7KA 1BZSA 1GO7P 1Q3AA 4I03A 3DWBA 3HDAP 2ERPA 4H3XA 3KHIA 3RTSA 2K9CA 1D7XA 1GE7A 1J7NA 5I3MA 3LJGA 3DTIA 4H30A 3TT4A 3I7IA 4L19A 4GUYA 1R54A 3ELMA 2X3AA 1HOVA 1KUIA 1CGFA 3ZVSA 2AYKA 2POJA 1YCMA 1GXDA 2X7MA 4WZVA 4DD8A 1MMQA 4JIJA 3LK8A 2N8RA 4Q1LA 1G12A 4JQGA 1OS9A 4A7BA 2JIHA 1QIBA 1D5JA 2MZHA 3EDZA 2XS4A 2Y6CA 3UVCA 5I0LA 5LABA 1KUHA 4I35A 1BSWA 3DPEA 2MZIA 3AYKA 1HY7A 2O3EA 4AYKA 3DSLA 1G9KA 2OI0A 1G49A 1HFSA 1CAQA 1CIZA 1CGLA 4PKTA 4DF9A 5L79A 1JANA 1XFVA 1B8YA 4XBHA 1PWPA 4XM7A 4PKSA 4G9LA 1RM8A 1A86A 4WF6A 1AKLA 1O0TA 3G42A 5I12A 3SHIA 1UTTA
chains in the Genus database with same CATH topology
4CTHA 2TCLA 2K2GA 1KUGA 4XCTA 3LUNA 2L0RA 1I1IP 5L7FA 3LUMA 4H82A 2CLTA 5D1TA 3DPFA 1AF0A 1CXVA 1B3DA 3HBVP 966CA 1A85A 3GBOA 3VI1A 1GO8P 3HY7A 4QKZA 1XFYA 2V4BA 1R1IA 1XFUA 1XUDA 2MLSA 5D1SA 4GR3A 2DW2A 1I73A 830CA 1Y8JA 1IABA 456CA 3LJTA 3EDHA 2W12A 2CKIA 5B5OA 1SATA 2OXWA 3TSKA 3ZUKA 3P1VA 1HFCA 3HDBA 4FXYP 1QIAA 1FM1A 4PKWA 2OXUA 1BKCE 2DW1A 5BOYA 4J4MA 3L0VA 1IAGA 1JKYA 2QPJA 1YP1A 1C3IA 1CGEA 1OMJA 4R3VA 1XFZA 2KRJA 1YOUA 1PWQA 1SU3A 3KRYA 1OM7A 2OVZA 2D1NA 1L6JA 1S4BP 3K7LA 1K7IA 2OW9A 2OXZA 4GF1A 5CZMA 1GKCA 1ND1A 1BM6A 2YUFA 3LQ0A 1PWVA 1Y0VA 1ZP5A 1KBCA 1USNA 2ERQA 4DV8A 3HY9A 1XUCA 2J0TA 1IAEA 3KWVC 2USNA 2EROA 4GR0A 3NX7A 1R1JA 3LIKA 3KECA 4IJOA 3G5CA 3DNGA 2WO8A 1G05A 3K7NA 1UEAA 4A3WA 1UMTA 1SLMA 1BUDA 4AXQA 3AIGA 1JIWP 1IACA 1XFXA 1QJIA 1EAKA 2J83A 4FVLA 1RMZA 1I76A 1ZVXA 2RJPA 1ROSA 3EDGA 3F18A 3RTTA 1JJ9A 2O36A 3KEJA 1D8MA 1MNCA 4XM6A 1GKDA 1R1HA 2I47A 3LGPA 2HU6A 4FXQA 3O64A 5D1UA 1FLSA 4DPEA 4H49A 4PKVA 1OM6A 1JAQA 2OW2A 2DDYA 3OHOA 4JP4A 1SRPA 3KEKA 3F17A 2OW0A 1JAPA 2JT6A 2PJTA 3EWJA 4WK7A 1ZXCA 3LKAA 1Y93A 4G0DA 4ZR5A 5JMYA 3F19A 4H76A 1EB6A 4GR8A 1WNIA 2SRTA 4H2EA 2JSDA 1BUVM 1BQOA 4GQLA 1HV5A 3DL1A 3EHYA 2DW0A 3LIRA 2FV9A 5BOTA 1C8TA 1ATLA 3CKIA 1GE6A 2WO9A 3F15A 4ON1A 2RJQA 4XM8A 1CK7A 3ZXHA 1KUKA 2X3BA 4IUWA 1UTZA 1QICA 2AIGP 1XFWA 3TVCA 1QJJA 1D8FA 4AIGA 3AYUA 2XS3A 1XURA 3Q2HA 4HMAA 1G4KA 1MMPA 3HYGA 1HTDA 3B8ZA 5B5PA 3HBUP 2A8HA 3Q2GA 1DTHA 4JPAA 2W15A 4H84A 1ZTQA 3WV1A 5CUHA 1Z3JA 3N2VA 1MMRA 5H8XA 3U1RA 1PWWA 3MA2A 3BA0A 4PKUA 3V96B 1JK3A 5D7WA 4WKIA 3KMCA 1R55A 1JIZA 4IN9A 1BKCA 1O0QA 3P24A 3VTGA 2MLRA 3EDIA 2OVXA 2W0DA 1IAAA 2Z2DA 3LJZA 3LEAA 1ASTA 3OHLA 1K7GA 1YQYA 2OW1A 1SLNA 3B92A 1FBLA 2WOAA 4ILWD 3WV3A 4JA1A 5I4OA 1AYKA 4EFSA 5I2ZA 2DDFA 3WV2A 1JH1A 1PWUA 2OY4A 2YB9A 3DTEA 2FV5A 5BPAA 1EUBA 1GE5A 3HB2P 3LMCA 3LE9A 1H71P 1ZXVA 1K7QA 1BKCI 3TS4A 4L7AA 3USNA 1MMBA 4WKEA 1IADA 3B2ZA 3F16A 2E3XA 1BQQM 2YIGA 1OS2A 1OM8A 1SMPA 4PKQA 2OZRA 1UMSA 4L6TA 1KUFA 3LILA 3LQBA 4H1QA 2W13A 3I7GA 2Y6DA 5D2BA 4PKRA 2JT5A 2MZEA 4AUOA 4GWNA 5CXAA 2D1OA 3E8RA 5I43A 3N2UA 5D3CA 3L0TA 1OO9A 2OY2A 1KAPP 1CQRA 3O2XA 3F1AA 1DMTA 1ZS0A 3EHXA 2JNPA 1JAOA 2E2DA 3DTKA 4GWMA 4HX3A 1BIWA 1QUAA 4L63A 4FU4A 2W14A 2X3CA 3KMEA 1C7KA 1BZSA 1GO7P 1Q3AA 4I03A 3DWBA 3HDAP 2ERPA 4H3XA 3KHIA 3RTSA 2K9CA 1D7XA 1GE7A 1J7NA 5I3MA 3LJGA 3DTIA 4H30A 3TT4A 3I7IA 4L19A 4GUYA 1R54A 3ELMA 2X3AA 1HOVA 1KUIA 1CGFA 3ZVSA 2AYKA 2POJA 1YCMA 1GXDA 2X7MA 4WZVA 4DD8A 1MMQA 4JIJA 3LK8A 2N8RA 4Q1LA 1G12A 4JQGA 1OS9A 4A7BA 2JIHA 1QIBA 1D5JA 2MZHA 3EDZA 2XS4A 2Y6CA 3UVCA 5I0LA 5LABA 1KUHA 4I35A 1BSWA 3DPEA 2MZIA 3AYKA 1HY7A 2O3EA 4AYKA 3DSLA 1G9KA 2OI0A 1G49A 1HFSA 1CAQA 1CIZA 1CGLA 4PKTA 4DF9A 5L79A 1JANA 1XFVA 1B8YA 4XBHA 1PWPA 4XM7A 4PKSA 4G9LA 1RM8A 1A86A 4WF6A 1AKLA 1O0TA 3G42A 5I12A 3SHIA 1UTTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CTH A;  2TCL A;  2K2G A;  1KUG A;  4XCT A;  3LUN A;  2L0R A;  1I1I P;  5L7F A;  3LUM A;  4H82 A;  2CLT A;  5D1T A;  3DPF A;  1AF0 A;  1CXV A;  1B3D A;  3HBV P;  966C A;  1A85 A;  3GBO A;  3VI1 A;  1GO8 P;  3HY7 A;  4QKZ A;  1XFY A;  2V4B A;  1R1I A;  1XFU A;  1XUD A;  2MLS A;  5D1S A;  4GR3 A;  2DW2 A;  1I73 A;  830C A;  1Y8J A;  1IAB A;  456C A;  3LJT A;  3EDH A;  2W12 A;  2CKI A;  5B5O A;  1SAT A;  2OXW A;  3TSK A;  3ZUK A;  3P1V A;  1HFC A;  3HDB A;  4FXY P;  1QIA A;  1FM1 A;  4PKW A;  2OXU A;  1BKC E;  2DW1 A;  5BOY A;  4J4M A;  3L0V A;  1IAG A;  1JKY A;  2QPJ A;  1YP1 A;  1C3I A;  1CGE A;  1OMJ A;  4R3V A;  1XFZ A;  2KRJ A;  1YOU A;  1PWQ A;  1SU3 A;  3KRY A;  1OM7 A;  2OVZ A;  2D1N A;  1L6J A;  1S4B P;  3K7L A;  1K7I A;  2OW9 A;  2OXZ A;  4GF1 A;  5CZM A;  1GKC A;  1ND1 A;  1BM6 A;  3LQ0 A;  1PWV A;  1Y0V A;  1ZP5 A;  1KBC A;  1USN A;  2ERQ A;  4DV8 A;  3HY9 A;  1XUC A;  2J0T A;  1IAE A;  3KWV C;  2USN A;  2ERO A;  4GR0 A;  3NX7 A;  1R1J A;  3LIK A;  3KEC A;  4IJO A;  3G5C A;  3DNG A;  2WO8 A;  1G05 A;  3K7N A;  1UEA A;  4A3W A;  1UMT A;  1SLM A;  1BUD A;  4AXQ A;  3AIG A;  1JIW P;  1IAC A;  1XFX A;  1QJI A;  1EAK A;  2J83 A;  4FVL A;  1RMZ A;  1I76 A;  1ZVX A;  2RJP A;  1ROS A;  3EDG A;  3F18 A;  3RTT A;  1JJ9 A;  2O36 A;  3KEJ A;  1D8M A;  1MNC A;  4XM6 A;  1GKD A;  1R1H A;  2I47 A;  3LGP A;  2HU6 A;  4FXQ A;  3O64 A;  5D1U A;  1FLS A;  4DPE A;  4H49 A;  4PKV A;  1OM6 A;  1JAQ A;  2OW2 A;  2DDY A;  3OHO A;  4JP4 A;  1SRP A;  3KEK A;  3F17 A;  2OW0 A;  1JAP A;  2JT6 A;  2PJT A;  3EWJ A;  4WK7 A;  1ZXC A;  3LKA A;  1Y93 A;  4G0D A;  4ZR5 A;  5JMY A;  3F19 A;  4H76 A;  1EB6 A;  4GR8 A;  1WNI A;  2SRT A;  4H2E A;  2JSD A;  1BUV M;  1BQO A;  4GQL A;  1HV5 A;  3DL1 A;  3EHY A;  2DW0 A;  3LIR A;  2FV9 A;  5BOT A;  1C8T A;  1ATL A;  3CKI A;  1GE6 A;  2WO9 A;  3F15 A;  4ON1 A;  2RJQ A;  4XM8 A;  1CK7 A;  3ZXH A;  1KUK A;  2X3B A;  4IUW A;  1UTZ A;  1QIC A;  2AIG P;  1XFW A;  3TVC A;  1QJJ A;  1D8F A;  4AIG A;  3AYU A;  2XS3 A;  1XUR A;  3Q2H A;  4HMA A;  1G4K A;  1MMP A;  3HYG A;  1HTD A;  3B8Z A;  5B5P A;  3HBU P;  2A8H A;  3Q2G A;  1DTH A;  4JPA A;  2W15 A;  4H84 A;  1ZTQ A;  3WV1 A;  5CUH A;  1Z3J A;  3N2V A;  1MMR A;  5H8X A;  3U1R A;  1PWW A;  3MA2 A;  3BA0 A;  4PKU A;  3V96 B;  1JK3 A;  5D7W A;  4WKI A;  3KMC A;  1R55 A;  1JIZ A;  4IN9 A;  1BKC A;  1O0Q A;  3P24 A;  3VTG A;  2MLR A;  3EDI A;  2OVX A;  2W0D A;  1IAA A;  2Z2D A;  3LJZ A;  3LEA A;  1AST A;  3OHL A;  1K7G A;  1YQY A;  2OW1 A;  1SLN A;  3B92 A;  1FBL A;  2WOA A;  4ILW D;  3WV3 A;  4JA1 A;  5I4O A;  1AYK A;  4EFS A;  5I2Z A;  2DDF A;  3WV2 A;  1JH1 A;  1PWU A;  2OY4 A;  2YB9 A;  2FV5 A;  5BPA A;  1EUB A;  1GE5 A;  3HB2 P;  3LMC A;  3LE9 A;  1H71 P;  1ZXV A;  1K7Q A;  1BKC I;  3TS4 A;  3USN A;  1MMB A;  4WKE A;  1IAD A;  3B2Z A;  3F16 A;  2E3X A;  1BQQ M;  2YIG A;  1OS2 A;  1OM8 A;  1SMP A;  4PKQ A;  2OZR A;  1UMS A;  4L6T A;  1KUF A;  3LIL A;  3LQB A;  4H1Q A;  2W13 A;  3I7G A;  2Y6D A;  5D2B A;  4PKR A;  2JT5 A;  2MZE A;  4AUO A;  4GWN A;  5CXA A;  2D1O A;  3E8R A;  5I43 A;  3N2U A;  5D3C A;  3L0T A;  1OO9 A;  2OY2 A;  1KAP P;  1CQR A;  3O2X A;  3F1A A;  1DMT A;  1ZS0 A;  3EHX A;  2JNP A;  1JAO A;  2E2D A;  4GWM A;  4HX3 A;  1BIW A;  1QUA A;  4L63 A;  4FU4 A;  2W14 A;  2X3C A;  3KME A;  1C7K A;  1BZS A;  1GO7 P;  1Q3A A;  4I03 A;  3DWB A;  3HDA P;  2ERP A;  4H3X A;  3KHI A;  3RTS A;  2K9C A;  1D7X A;  1GE7 A;  1J7N A;  5I3M A;  3LJG A;  4H30 A;  3TT4 A;  3I7I A;  4L19 A;  4GUY A;  1R54 A;  3ELM A;  2X3A A;  1HOV A;  1KUI A;  1CGF A;  3ZVS A;  2AYK A;  2POJ A;  1YCM A;  1GXD A;  2X7M A;  4WZV A;  4DD8 A;  1MMQ A;  4JIJ A;  3LK8 A;  2N8R A;  4Q1L A;  1G12 A;  4JQG A;  1OS9 A;  4A7B A;  2JIH A;  1QIB A;  1D5J A;  2MZH A;  3EDZ A;  2XS4 A;  2Y6C A;  3UVC A;  5I0L A;  5LAB A;  1KUH A;  4I35 A;  1BSW A;  3DPE A;  2MZI A;  3AYK A;  1HY7 A;  2O3E A;  4AYK A;  3DSL A;  1G9K A;  2OI0 A;  1G49 A;  1HFS A;  1CAQ A;  1CIZ A;  1CGL A;  4PKT A;  4DF9 A;  5L79 A;  1JAN A;  1XFV A;  1B8Y A;  4XBH A;  1PWP A;  4XM7 A;  4PKS A;  4G9L A;  1RM8 A;  1A86 A;  4WF6 A;  1AKL A;  1O0T A;  3G42 A;  5I12 A;  3SHI A;  1UTT A; 
#chains in the Genus database with same CATH topology
 4CTH A;  2TCL A;  2K2G A;  1KUG A;  4XCT A;  3LUN A;  2L0R A;  1I1I P;  5L7F A;  3LUM A;  4H82 A;  2CLT A;  5D1T A;  3DPF A;  1AF0 A;  1CXV A;  1B3D A;  3HBV P;  966C A;  1A85 A;  3GBO A;  3VI1 A;  1GO8 P;  3HY7 A;  4QKZ A;  1XFY A;  2V4B A;  1R1I A;  1XFU A;  1XUD A;  2MLS A;  5D1S A;  4GR3 A;  2DW2 A;  1I73 A;  830C A;  1Y8J A;  1IAB A;  456C A;  3LJT A;  3EDH A;  2W12 A;  2CKI A;  5B5O A;  1SAT A;  2OXW A;  3TSK A;  3ZUK A;  3P1V A;  1HFC A;  3HDB A;  4FXY P;  1QIA A;  1FM1 A;  4PKW A;  2OXU A;  1BKC E;  2DW1 A;  5BOY A;  4J4M A;  3L0V A;  1IAG A;  1JKY A;  2QPJ A;  1YP1 A;  1C3I A;  1CGE A;  1OMJ A;  4R3V A;  1XFZ A;  2KRJ A;  1YOU A;  1PWQ A;  1SU3 A;  3KRY A;  1XM5 A;  1OM7 A;  2OVZ A;  2D1N A;  1L6J A;  1S4B P;  3K7L A;  1K7I A;  2OW9 A;  2OXZ A;  4GF1 A;  5CZM A;  1GKC A;  1ND1 A;  1BM6 A;  2YUF A;  3LQ0 A;  1PWV A;  1Y0V A;  1ZP5 A;  1KBC A;  1USN A;  2ERQ A;  4DV8 A;  3HY9 A;  1XUC A;  2J0T A;  1IAE A;  3KWV C;  2USN A;  2ERO A;  4GR0 A;  3NX7 A;  1R1J A;  3LIK A;  3KEC A;  4IJO A;  3G5C A;  3DNG A;  2WO8 A;  1G05 A;  3K7N A;  1UEA A;  1XAX A;  4A3W A;  1UMT A;  1SLM A;  1BUD A;  4AXQ A;  3AIG A;  1JIW P;  1IAC A;  1XFX A;  1QJI A;  1EAK A;  2J83 A;  4FVL A;  1RMZ A;  1I76 A;  1ZVX A;  2RJP A;  1ROS A;  3EDG A;  3F18 A;  3RTT A;  1JJ9 A;  2O36 A;  3KEJ A;  1D8M A;  1MNC A;  4XM6 A;  1GKD A;  1R1H A;  2I47 A;  3LGP A;  2HU6 A;  4FXQ A;  3O64 A;  5D1U A;  1FLS A;  4DPE A;  4H49 A;  4PKV A;  1OM6 A;  1JAQ A;  2OW2 A;  2DDY A;  3OHO A;  4JP4 A;  1SRP A;  3KEK A;  3F17 A;  2OW0 A;  1JAP A;  2JT6 A;  2PJT A;  3EWJ A;  4WK7 A;  1ZXC A;  3LKA A;  1Y93 A;  4G0D A;  4ZR5 A;  5JMY A;  3F19 A;  4H76 A;  1EB6 A;  4GR8 A;  1WNI A;  2SRT A;  4H2E A;  2JSD A;  1BUV M;  1BQO A;  4GQL A;  1HV5 A;  3DL1 A;  3EHY A;  2DW0 A;  1OZ9 A;  3LIR A;  2FV9 A;  5BOT A;  1C8T A;  1ATL A;  3CKI A;  1GE6 A;  2WO9 A;  3F15 A;  4ON1 A;  2RJQ A;  4XM8 A;  1CK7 A;  3ZXH A;  1KUK A;  2X3B A;  4IUW A;  1UTZ A;  1QIC A;  2AIG P;  1XFW A;  3TVC A;  1QJJ A;  1D8F A;  4AIG A;  3AYU A;  2XS3 A;  1XUR A;  3Q2H A;  4HMA A;  1G4K A;  1MMP A;  3HYG A;  1HTD A;  3B8Z A;  5B5P A;  3HBU P;  2A8H A;  3Q2G A;  1DTH A;  4JPA A;  2W15 A;  4H84 A;  1ZTQ A;  3WV1 A;  5CUH A;  1Z3J A;  3N2V A;  1MMR A;  5H8X A;  3U1R A;  1PWW A;  3MA2 A;  3BA0 A;  4PKU A;  3V96 B;  1JK3 A;  5D7W A;  4WKI A;  3KMC A;  1R55 A;  1JIZ A;  4IN9 A;  1BKC A;  1O0Q A;  3P24 A;  3VTG A;  2MLR A;  3EDI A;  2OVX A;  2W0D A;  1IAA A;  2Z2D A;  3LJZ A;  3LEA A;  1AST A;  3OHL A;  1K7G A;  1YQY A;  2OW1 A;  1SLN A;  3B92 A;  1FBL A;  2WOA A;  4ILW D;  3WV3 A;  4JA1 A;  5I4O A;  1AYK A;  4EFS A;  5I2Z A;  1TVI A;  2DDF A;  3WV2 A;  1JH1 A;  1PWU A;  2OY4 A;  2YB9 A;  3DTE A;  2FV5 A;  5BPA A;  1EUB A;  1GE5 A;  3HB2 P;  3LMC A;  3LE9 A;  1H71 P;  1ZXV A;  1K7Q A;  1BKC I;  3TS4 A;  4L7A A;  3USN A;  1MMB A;  4WKE A;  1IAD A;  3B2Z A;  3F16 A;  2E3X A;  1BQQ M;  2YIG A;  1OS2 A;  1OM8 A;  1SMP A;  4PKQ A;  2OZR A;  1UMS A;  4L6T A;  1KUF A;  3LIL A;  3LQB A;  4H1Q A;  2W13 A;  3I7G A;  2Y6D A;  5D2B A;  4PKR A;  2JT5 A;  2MZE A;  4AUO A;  4GWN A;  5CXA A;  2D1O A;  3E8R A;  5I43 A;  3N2U A;  5D3C A;  3L0T A;  1OO9 A;  2OY2 A;  1KAP P;  1CQR A;  3O2X A;  3F1A A;  1DMT A;  1ZS0 A;  3EHX A;  2JNP A;  1JAO A;  2E2D A;  3DTK A;  4GWM A;  4HX3 A;  1BIW A;  1QUA A;  4L63 A;  4FU4 A;  2W14 A;  2X3C A;  3KME A;  1C7K A;  1BZS A;  1GO7 P;  1Q3A A;  4I03 A;  3DWB A;  3HDA P;  2ERP A;  4H3X A;  3KHI A;  3RTS A;  2K9C A;  1D7X A;  1GE7 A;  1J7N A;  5I3M A;  3LJG A;  3DTI A;  4H30 A;  3TT4 A;  3I7I A;  4L19 A;  4GUY A;  1R54 A;  3ELM A;  2X3A A;  1HOV A;  1KUI A;  1CGF A;  3ZVS A;  2AYK A;  2POJ A;  1YCM A;  1GXD A;  2X7M A;  4WZV A;  4DD8 A;  1MMQ A;  4JIJ A;  3LK8 A;  2N8R A;  4Q1L A;  1G12 A;  4JQG A;  1OS9 A;  4A7B A;  2JIH A;  1QIB A;  1D5J A;  2MZH A;  3EDZ A;  2XS4 A;  2Y6C A;  3UVC A;  5I0L A;  5LAB A;  1KUH A;  4I35 A;  1BSW A;  3DPE A;  2MZI A;  3AYK A;  1HY7 A;  2O3E A;  4AYK A;  3DSL A;  1G9K A;  2OI0 A;  1G49 A;  1HFS A;  1CAQ A;  1CIZ A;  1CGL A;  4PKT A;  4DF9 A;  5L79 A;  1JAN A;  1XFV A;  1B8Y A;  4XBH A;  1PWP A;  4XM7 A;  4PKS A;  4G9L A;  1RM8 A;  1A86 A;  4WF6 A;  1AKL A;  1O0T A;  3G42 A;  5I12 A;  3SHI A;  1UTT A; 
#chains in the Genus database with same CATH homology
 4CTH A;  2TCL A;  2K2G A;  1KUG A;  4XCT A;  3LUN A;  2L0R A;  1I1I P;  5L7F A;  3LUM A;  4H82 A;  2CLT A;  5D1T A;  3DPF A;  1AF0 A;  1CXV A;  1B3D A;  3HBV P;  966C A;  1A85 A;  3GBO A;  3VI1 A;  1GO8 P;  3HY7 A;  4QKZ A;  1XFY A;  2V4B A;  1R1I A;  1XFU A;  1XUD A;  2MLS A;  5D1S A;  4GR3 A;  2DW2 A;  1I73 A;  830C A;  1Y8J A;  1IAB A;  456C A;  3LJT A;  3EDH A;  2W12 A;  2CKI A;  5B5O A;  1SAT A;  2OXW A;  3TSK A;  3ZUK A;  3P1V A;  1HFC A;  3HDB A;  4FXY P;  1QIA A;  1FM1 A;  4PKW A;  2OXU A;  1BKC E;  2DW1 A;  5BOY A;  4J4M A;  3L0V A;  1IAG A;  1JKY A;  2QPJ A;  1YP1 A;  1C3I A;  1CGE A;  1OMJ A;  4R3V A;  1XFZ A;  2KRJ A;  1YOU A;  1PWQ A;  1SU3 A;  3KRY A;  1OM7 A;  2OVZ A;  2D1N A;  1L6J A;  1S4B P;  3K7L A;  1K7I A;  2OW9 A;  2OXZ A;  4GF1 A;  5CZM A;  1GKC A;  1ND1 A;  1BM6 A;  2YUF A;  3LQ0 A;  1PWV A;  1Y0V A;  1ZP5 A;  1KBC A;  1USN A;  2ERQ A;  4DV8 A;  3HY9 A;  1XUC A;  2J0T A;  1IAE A;  3KWV C;  2USN A;  2ERO A;  4GR0 A;  3NX7 A;  1R1J A;  3LIK A;  3KEC A;  4IJO A;  3G5C A;  3DNG A;  2WO8 A;  1G05 A;  3K7N A;  1UEA A;  4A3W A;  1UMT A;  1SLM A;  1BUD A;  4AXQ A;  3AIG A;  1JIW P;  1IAC A;  1XFX A;  1QJI A;  1EAK A;  2J83 A;  4FVL A;  1RMZ A;  1I76 A;  1ZVX A;  2RJP A;  1ROS A;  3EDG A;  3F18 A;  3RTT A;  1JJ9 A;  2O36 A;  3KEJ A;  1D8M A;  1MNC A;  4XM6 A;  1GKD A;  1R1H A;  2I47 A;  3LGP A;  2HU6 A;  4FXQ A;  3O64 A;  5D1U A;  1FLS A;  4DPE A;  4H49 A;  4PKV A;  1OM6 A;  1JAQ A;  2OW2 A;  2DDY A;  3OHO A;  4JP4 A;  1SRP A;  3KEK A;  3F17 A;  2OW0 A;  1JAP A;  2JT6 A;  2PJT A;  3EWJ A;  4WK7 A;  1ZXC A;  3LKA A;  1Y93 A;  4G0D A;  4ZR5 A;  5JMY A;  3F19 A;  4H76 A;  1EB6 A;  4GR8 A;  1WNI A;  2SRT A;  4H2E A;  2JSD A;  1BUV M;  1BQO A;  4GQL A;  1HV5 A;  3DL1 A;  3EHY A;  2DW0 A;  3LIR A;  2FV9 A;  5BOT A;  1C8T A;  1ATL A;  3CKI A;  1GE6 A;  2WO9 A;  3F15 A;  4ON1 A;  2RJQ A;  4XM8 A;  1CK7 A;  3ZXH A;  1KUK A;  2X3B A;  4IUW A;  1UTZ A;  1QIC A;  2AIG P;  1XFW A;  3TVC A;  1QJJ A;  1D8F A;  4AIG A;  3AYU A;  2XS3 A;  1XUR A;  3Q2H A;  4HMA A;  1G4K A;  1MMP A;  3HYG A;  1HTD A;  3B8Z A;  5B5P A;  3HBU P;  2A8H A;  3Q2G A;  1DTH A;  4JPA A;  2W15 A;  4H84 A;  1ZTQ A;  3WV1 A;  5CUH A;  1Z3J A;  3N2V A;  1MMR A;  5H8X A;  3U1R A;  1PWW A;  3MA2 A;  3BA0 A;  4PKU A;  3V96 B;  1JK3 A;  5D7W A;  4WKI A;  3KMC A;  1R55 A;  1JIZ A;  4IN9 A;  1BKC A;  1O0Q A;  3P24 A;  3VTG A;  2MLR A;  3EDI A;  2OVX A;  2W0D A;  1IAA A;  2Z2D A;  3LJZ A;  3LEA A;  1AST A;  3OHL A;  1K7G A;  1YQY A;  2OW1 A;  1SLN A;  3B92 A;  1FBL A;  2WOA A;  4ILW D;  3WV3 A;  4JA1 A;  5I4O A;  1AYK A;  4EFS A;  5I2Z A;  2DDF A;  3WV2 A;  1JH1 A;  1PWU A;  2OY4 A;  2YB9 A;  3DTE A;  2FV5 A;  5BPA A;  1EUB A;  1GE5 A;  3HB2 P;  3LMC A;  3LE9 A;  1H71 P;  1ZXV A;  1K7Q A;  1BKC I;  3TS4 A;  4L7A A;  3USN A;  1MMB A;  4WKE A;  1IAD A;  3B2Z A;  3F16 A;  2E3X A;  1BQQ M;  2YIG A;  1OS2 A;  1OM8 A;  1SMP A;  4PKQ A;  2OZR A;  1UMS A;  4L6T A;  1KUF A;  3LIL A;  3LQB A;  4H1Q A;  2W13 A;  3I7G A;  2Y6D A;  5D2B A;  4PKR A;  2JT5 A;  2MZE A;  4AUO A;  4GWN A;  5CXA A;  2D1O A;  3E8R A;  5I43 A;  3N2U A;  5D3C A;  3L0T A;  1OO9 A;  2OY2 A;  1KAP P;  1CQR A;  3O2X A;  3F1A A;  1DMT A;  1ZS0 A;  3EHX A;  2JNP A;  1JAO A;  2E2D A;  3DTK A;  4GWM A;  4HX3 A;  1BIW A;  1QUA A;  4L63 A;  4FU4 A;  2W14 A;  2X3C A;  3KME A;  1C7K A;  1BZS A;  1GO7 P;  1Q3A A;  4I03 A;  3DWB A;  3HDA P;  2ERP A;  4H3X A;  3KHI A;  3RTS A;  2K9C A;  1D7X A;  1GE7 A;  1J7N A;  5I3M A;  3LJG A;  3DTI A;  4H30 A;  3TT4 A;  3I7I A;  4L19 A;  4GUY A;  1R54 A;  3ELM A;  2X3A A;  1HOV A;  1KUI A;  1CGF A;  3ZVS A;  2AYK A;  2POJ A;  1YCM A;  1GXD A;  2X7M A;  4WZV A;  4DD8 A;  1MMQ A;  4JIJ A;  3LK8 A;  2N8R A;  4Q1L A;  1G12 A;  4JQG A;  1OS9 A;  4A7B A;  2JIH A;  1QIB A;  1D5J A;  2MZH A;  3EDZ A;  2XS4 A;  2Y6C A;  3UVC A;  5I0L A;  5LAB A;  1KUH A;  4I35 A;  1BSW A;  3DPE A;  2MZI A;  3AYK A;  1HY7 A;  2O3E A;  4AYK A;  3DSL A;  1G9K A;  2OI0 A;  1G49 A;  1HFS A;  1CAQ A;  1CIZ A;  1CGL A;  4PKT A;  4DF9 A;  5L79 A;  1JAN A;  1XFV A;  1B8Y A;  4XBH A;  1PWP A;  4XM7 A;  4PKS A;  4G9L A;  1RM8 A;  1A86 A;  4WF6 A;  1AKL A;  1O0T A;  3G42 A;  5I12 A;  3SHI A;  1UTT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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